3I06A

Crystal structure of cruzain covalently bound to a purine nitrile
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
215
structure length
214
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification and optimization of inhibitors of trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma cruzi
molecule keywords Cruzipain
total genus 71
structure length 214
sequence length 215
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2009-06-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3i06A00
3PW3A 1AU2A 1TLOA 3U8EA 4BS5A 2DC9A 1S4VA 4BSQA 1YK7A 1EWMA 1AU3A 1THEA 3HHAA 1POPA 3IOQA 6PADA 1PCIA 3MORA 2DCAA 1EWPA 1DF0A 2F7DA 4QBBA 4PI3A 2AYOA 3K24A 1PPPA 3RVXA 1SP4B 2B1NA 1ME4A 1MEGA 5CVMA 2YJ9A 3MHSA 3BPMA 1GMYA 3P5WA 2YJBA 2PREA 1EWOA 1X9YA 4XR7A 1NLJA 2AUZA 4AXLA 1Y08A 3P5XA 3RVVA 1CPJA 1NL6A 4ZUXU 3LFYA 2AUXA 1CS8A 1NB3A 1ITOA 1GECE 1SNKA 2XU5A 1QMYA 4CZWA 2PNSA 2WBFX 3OVZA 1YK8A 3C9EA 1EF7A 3KSEA 4QRVA 2PADA 4BPVA 3BOWA 3S3QA 3PBHA 3AI8A 1PIPA 3BWKA 3N3GA 3IV2A 3PNRA 1CSBB 1CQDA 4X6IA 3V6CA 2VHSA 1AYUA 2AYNA 4RY2A 2NQDB 2E01A 2ARYA 4YYRA 2FT2A 2IBIA 3IEJA 1MDWA 2HHNA 3IMAA 2E00A 1TU6A 1BGOA 4W5BA 3OF8A 4KLBA 2G7YA 1YALA 5F02A 3TNXA 2IPPB 2CB5A 4QH6A 4CDFB 2E03A 4P6EA 1F2CA 1PPDA 5CVOB 3BPFA 2DC6A 4CDDB 1U9WA 1YVBA 3QT4A 4G54A 4I07A 1ZIVA 1VJVA 3M99A 4MZSA 5A24A 1K3BB 1M6DA 4N79A 2DJGB 1BP4A 1CJLA 2DZZA 3KFQA 1AYVA 3RVWA 2XU1A 2BDLA 2ACTA 4X6HA 1PPOA 4PADA 2YJ8A 3ERVA 2GFOA 3D6SA 1Y4HA 2AVWA 2R9OA 1CTEA 1AU4A 1BY8A 1U9VA 2FO5A 4I04A 4P6GA 4QRGA 1MHWA 5K16A 3IHPA 2YJCA 4MZOA 3KWZA 5J94A 2XU4A 3WXGA 1PADA 3OISA 3WXEA 4W5CA 1PBHA 2FQ9A 2PBHA 1KFXL 3I3TA 3WXFA 4N8WA 2ATOA 1KXRA 1YT7A 5JH3A 5PADA 3V6EA 2NQGA 1KHQA 2FUDA 1F2AA 4XUIA 4WA6A 1GLOA 1Q6KA 4FJCA 2R6NA 4FIPA 1JQPA 3DF0A 3ZUAA 1U9QX 3B79A 4YYWA 1NB5A 3I06A 3LXSA 2E02A 2JQGR 4YVAA 4YYVA 2R9NA 1F29A 2FRAA 4FK5A 3K9MA 3H8CA 3O0UA 2DZYA 3NHEA 7PCKA 2GHUA 3N3KA 2FYEA 3HHIA 4AXMA 4BQVA 3E1ZB 4BS6A 3CH2X 9PAPA 1PPNA 1PXVA 4MSXA 1MS6A 2VHFA 2DC7A 1PE6A 4I05A 3BC3A 1ICFA 1ATKA 1U9XA 3F75A 2DC8A 3HD3A 2HXZA 1CVZA 3H6SA 2P86A 2R9FA 3KWBX 4CDCB 2AIMA 4W4UA 3O1GA 2YJ2A 4X6JA 2AU1A 3F5VA 1AU0A 4YYUA 2DCBA 2FTDA 3OVXA 1MEMA 2HD5A 2HH5A 1U5IA 3S3RA 3GCBA 1VSNA 2JQFR 3USVA 2OULA 1KFUL 2F1GA 2FRQA 3OF9A 5CHTA 1DEUA 3KKUA 1IWDA 2Y6EA 3H8BA 3MHHA 4YV8A 2P0RA 2C0YA 5CHVA 8PCHA 4YYQA 1NPZA 3H89A 3BCNA 3PDFA 5EGWA 3H7DA 4Q8HA 2P7UA 3P5VA 4N4ZA 3CBKA 3QJ3A 2G8EA 2R9MA 2CIOA 1QXPA 5CVNB 2G6DA 1TL9A 3IUTA 1CB5A 1AYWA 1AIMA 1GCBA 3HWNA 1QOLA 2B1MA 3KW9A 4OEMA 2AS8A 3K8UA 4YYSA 3QSDA 3KX1A 4PP2E 1F2BA 2Y5BA 2NQIA 2O6XA 3CH3X 2OP3A 1XKGA 4DMXA 2NQAA 1A6RA 2DCDA 1O0EA 3MTNA 1AECA 1STFE 5JA7A 1NQCA 5FPWA 2XU3A 1EWLA 1KHPA 4PP1A 1QDQA 1FH0A 3P5UA 2DCCA 4HWYA 2DJFB 1ZCMA 2BDZA 2R9CA 2OZ2A 3CBJA 1HUCB 1ME3A 4K7CA 4Q8GA 4CDEB 1MIRA 3N4CA 2G8JA 2H7JA 1CV8A 4DMYA 1BQIA 4OELA 5EF4A 4QRXA
chains in the Genus database with same CATH superfamily
3PW3A 3E9SA 3PSEA 1AU2A 1TLOA 3U8EA 4BS5A 2DC9A 1S4VA 4BSQA 1YK7A 1EWMA 1AU3A 1THEA 3HHAA 1POPA 3IOQA 6PADA 1PCIA 3MORA 2DCAA 1EWPA 1DF0A 2F7DA 4QBBA 4PI3A 2AYOA 2BTWA 3K24A 3PT2A 1PPPA 3RVXA 1SP4B 2B1NA 5JZEA 1ME4A 1MEGA 5CVMA 2YJ9A 3MHSA 3BPMA 1GMYA 3P5WA 4PT5A 2YJBA 2PREA 1EWOA 1X9YA 4XR7A 1NLJA 2AUZA 4AXLA 1Y08A 3P5XA 3RVVA 1CPJA 1NL6A 4ZUXU 3PHUA 3LFYA 2AUXA 4BOUA 1CS8A 4ZTBA 1NB3A 3BY4A 1ITOA 1GECE 1SNKA 2XU5A 2AGAA 4RNAA 4OW0A 3IFUA 1QMYA 4CZWA 2PNSA 2WBFX 3OVZA 3PHXA 1YK8A 3C9EA 1EF7A 3KSEA 4QRVA 2PADA 4BPVA 3BOWA 3S3QA 4HXDB 3PBHA 3AI8A 1PIPA 3BWKA 4MI7A 3N3GA 3IV2A 3PNRA 1CSBB 1CQDA 4X6IA 3V6CA 2VHSA 1AYUA 2AYNA 4RY2A 2NQDB 3BB7A 2E01A 4IP3A 2ARYA 3MP2A 4YYRA 2FT2A 2IBIA 3PHWA 3IEJA 1MDWA 2HHNA 3IMAA 2E00A 1TU6A 1BGOA 4W5BA 3OF8A 4KLBA 2G7YA 1YALA 5F02A 3TNXA 2IPPB 2CB5A 4QH6A 4CDFB 2E03A 4P6EA 1F2CA 1PPDA 5CVOB 4A5UA 3BPFA 2DC6A 4CDDB 1U9WA 1YVBA 3QT4A 3PRPA 4G54A 4I07A 4RF0A 1ZIVA 1VJVA 3M99A 4MZSA 5A24A 4GUAA 1K3BB 1M6DA 4N79A 2DJGB 1BP4A 1CJLA 2HWKA 2DZZA 3KFQA 1AYVA 3RVWA 2FE8A 3TMPA 2XU1A 5KO3A 2BDLA 2ACTA 4X6HA 1PPOA 4PADA 2YJ8A 3ERVA 2GFOA 3D6SA 1Y4HA 2AVWA 2R9OA 1CTEA 1AU4A 1BY8A 1U9VA 1DKIA 4BOQA 2FO5A 4I04A 4P6GA 4QRGA 1MHWA 5K16A 3IHPA 2YJCA 4MZOA 3KWZA 5J94A 2XU4A 3WXGA 1PADA 3OISA 3WXEA 4W5CA 1PBHA 2FQ9A 2PBHA 1KFXL 4MM3B 3I3TA 3WXFA 4N8WA 4RKXA 2ATOA 5E6JA 1KXRA 1YT7A 5JH3A 5PADA 3V6EA 2NQGA 2J7QA 1KHQA 2FUDA 1F2AA 3B21A 4XUIA 4WA6A 1GLOA 1Q6KA 4FJCA 2DOSA 2R6NA 4FIPA 1JQPA 3DF0A 3ZUAA 1U9QX 3B79A 4YYWA 1YZBA 3W30A 1NB5A 3I06A 3LXSA 3BBAA 2E02A 2JQGR 2BU3A 4YVAA 4YYVA 2R9NA 1F29A 2FRAA 4FK5A 3K9MA 3H8CA 3O0UA 2J7QC 3RNVA 2DZYA 3NHEA 7PCKA 2GHUA 3N3KA 2FYEA 3HHIA 4AXMA 4BQVA 3E1ZB 4BS6A 3CH2X 9PAPA 1PPNA 1PXVA 4D8IA 4MSXA 1MS6A 3O65A 2VHFA 2DC7A 4REZA 1PE6A 4I05A 2JRIA 3BC3A 4P16A 1ICFA 1ATKA 1U9XA 3F75A 2DC8A 3HD3A 2HXZA 4OVZB 1CVZA 3H6SA 2P86A 2R9FA 3KWBX 4CDCB 2AIMA 4W4UA 3O1GA 1UKFA 2YJ2A 4X6JA 2AU1A 3F5VA 1AU0A 2Z84A 4YYUA 2DCBA 2UZJA 2FTDA 3OVXA 1MEMA 2HD5A 2HH5A 1U5IA 3S3RA 3GCBA 1VSNA 2JQFR 3USVA 2OULA 1KFUL 2F1GA 2FRQA 3OF9A 4R3DA 5CHTA 1DEUA 3KKUA 1IWDA 2Y6EA 4OVZA 3H8BA 3MHHA 4YV8A 2P0RA 1PVJA 2C0YA 5CHVA 8PCHA 4WURA 4YYQA 1NPZA 3H89A 3PRMA 4D8EA 3BCNA 3PDFA 4RF1A 5EGWA 3H7DA 4Q8HA 3P5VA 5EZQA 4N4ZA 3CBKA 3QJ3A 2G8EA 2R9MA 2CIOA 1QXPA 3MTVA 5CVNB 2G6DA 1TL9A 3IUTA 1CB5A 1AYWA 1AIMA 1GCBA 3HWNA 1QOLA 2B1MA 3KW9A 3MJ5A 4OEMA 2AS8A 3K8UA 4BOZA 4YYSA 3QSDA 4D8BA 3KX1A 4PP2E 3TRKA 4QRXA 1F2BA 2Y5BA 2NQIA 2O6XA 3CH3X 5EZSA 2OP3A 4IUMA 3OQCA 1XKGA 4DMXA 2NQAA 1A6RA 2DCDA 1O0EA 3MTNA 1AECA 1STFE 5JA7A 1NQCA 5FPWA 2XU3A 3W31A 1EWLA 1KHPA 4PP1A 1QDQA 1FH0A 3P5UA 2DCCA 4HWYA 2DJFB 2JTCA 1ZCMA 2BDZA 4XZXA 2R9CA 2OZ2A 3CBJA 1HUCB 1ME3A 4K7CA 4Q8GA 2BTWB 4M0WA 1MIRA 3N4CA 4BOPA 4CDEB 3C0RA 2G8JA 2H7JA 1CV8A 4DMYA 1BQIA 4OELA 5EF4A 4BOSA 3ZNHA 2P7UA
chains in the Genus database with same CATH topology
4NV7A 3PW3A 3LTWA 1AU2A 1TLOA 3U8EA 4BS5A 2DC9A 1S4VA 4BSQA 1YK7A 1EWMA 1AU3A 1THEA 3HHAA 1POPA 3IOQA 6PADA 1PCIA 3MORA 2DCAA 1EWPA 1DF0A 2F7DA 4QBBA 4PI3A 2AYOA 3K24A 1PPPA 3RVXA 1SP4B 2B1NA 1ME4A 1MEGA 5CVMA 2YJ9A 3MHSA 3BPMA 1GMYA 3P5WA 2YJBA 2PREA 1EWOA 1X9YA 4XR7A 1NLJA 2AUZA 4AXLA 1Y08A 3P5XA 3RVVA 1CPJA 1NL6A 4ZUXU 3LFYA 2AUXA 1CS8A 1NB3A 1ITOA 1GECE 1SNKA 2XU5A 1QMYA 4CZWA 2PNSA 2WBFX 3OVZA 1YK8A 3C9EA 1EF7A 3KSEA 4QRVA 2PADA 4BPVA 3BOWA 3S3QA 3PBHA 3AI8A 1PIPA 4BGFA 3BWKA 3N3GA 3IV2A 3PNRA 1CSBB 1CQDA 4X6IA 3V6CA 2VHSA 1AYUA 2AYNA 4RY2A 2NQDB 2E01A 2ARYA 4YYRA 1W6FA 2FT2A 2IBIA 3IEJA 1MDWA 2HHNA 3IMAA 2E00A 1TU6A 1BGOA 4W5BA 3OF8A 4KLBA 2G7YA 1YALA 5F02A 3TNXA 2IPPB 2CB5A 4QH6A 4CDFB 2E03A 4P6EA 1F2CA 1PPDA 5CVOB 3BPFA 2DC6A 4CDDB 1U9WA 1YVBA 3QT4A 4G54A 4I07A 1ZIVA 1VJVA 3M99A 4MZSA 5A24A 1K3BB 1M6DA 4N79A 2DJGB 1BP4A 1CJLA 2DZZA 3KFQA 1AYVA 3RVWA 2XU1A 2BDLA 2ACTA 4X6HA 1PPOA 4PADA 2YJ8A 3ERVA 2GFOA 1E2TA 3D6SA 1Y4HA 2AVWA 2R9OA 1CTEA 2VFBA 1AU4A 1BY8A 1U9VA 2FO5A 4I04A 4P6GA 4QRGA 1MHWA 5K16A 3IHPA 2YJCA 4MZOA 3KWZA 5J94A 2XU4A 3WXGA 1PADA 3OISA 3WXEA 4W5CA 1PBHA 2FQ9A 2PBHA 4C5PA 1KFXL 3I3TA 3WXFA 4N8WA 2ATOA 1KXRA 1YT7A 5JH3A 5PADA 3V6EA 2NQGA 1KHQA 2FUDA 1F2AA 4XUIA 4WA6A 1GLOA 1Q6KA 4FJCA 2R6NA 4FIPA 1JQPA 3DF0A 3ZUAA 1U9QX 3B79A 4YYWA 1NB5A 3I06A 3LXSA 2E02A 2JQGR 4YVAA 4YYVA 2R9NA 1F29A 2FRAA 4FK5A 3K9MA 3H8CA 3O0UA 2DZYA 3NHEA 1W5RA 7PCKA 2GHUA 3N3KA 2FYEA 3HHIA 4AXMA 4BQVA 3E1ZB 4BS6A 3CH2X 9PAPA 1PPNA 1PXVA 4MSXA 1MS6A 2VHFA 2DC7A 1PE6A 4I05A 3BC3A 1ICFA 1ATKA 1U9XA 2VFCA 3F75A 2DC8A 3HD3A 2HXZA 1CVZA 3H6SA 2P86A 2R9FA 3KWBX 4CDCB 2AIMA 4W4UA 3O1GA 2YJ2A 4X6JA 2AU1A 3F5VA 1AU0A 4YYUA 2DCBA 2FTDA 3OVXA 1MEMA 2HD5A 2HH5A 1U5IA 3S3RA 3GCBA 1VSNA 2JQFR 3USVA 2BSZA 2OULA 1KFUL 1GX3A 2F1GA 2FRQA 3OF9A 4B55A 5CHTA 1DEUA 3KKUA 1IWDA 2Y6EA 3H8BA 3MHHA 4YV8A 2P0RA 2C0YA 5CHVA 3D9WA 8PCHA 4YYQA 1NPZA 3H89A 3BCNA 3PDFA 5EGWA 3H7DA 4Q8HA 3P5VA 4N4ZA 3CBKA 3QJ3A 2G8EA 2R9MA 2CIOA 1QXPA 5CVNB 2G6DA 1TL9A 3IUTA 1W4TA 1CB5A 1AYWA 1AIMA 1GCBA 3HWNA 1QOLA 2B1MA 3KW9A 4OEMA 2AS8A 3K8UA 4YYSA 3QSDA 3KX1A 4PP2E 4QRXA 1F2BA 2Y5BA 2NQIA 2O6XA 3CH3X 2OP3A 1XKGA 4DMXA 2NQAA 1A6RA 2DCDA 1O0EA 3MTNA 1AECA 1STFE 5JA7A 1NQCA 4NV8A 4GUZA 5FPWA 2XU3A 1EWLA 1KHPA 4PP1A 1QDQA 1FH0A 3P5UA 2DCCA 4HWYA 2DJFB 1ZCMA 2BDZA 2R9CA 2OZ2A 3CBJA 1HUCB 1ME3A 4K7CA 4Q8GA 4CDEB 1MIRA 3N4CA 2G8JA 2H7JA 1CV8A 4DMYA 1BQIA 4OELA 5EF4A 2P7UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PW3 A;  1AU2 A;  1TLO A;  3U8E A;  4BS5 A;  2DC9 A;  1S4V A;  4BSQ A;  1YK7 A;  1EWM A;  1AU3 A;  1THE A;  3HHA A;  1POP A;  3IOQ A;  6PAD A;  1PCI A;  3MOR A;  2DCA A;  1EWP A;  1DF0 A;  2F7D A;  4QBB A;  4PI3 A;  2AYO A;  3K24 A;  1PPP A;  3RVX A;  1SP4 B;  2B1N A;  1ME4 A;  1MEG A;  5CVM A;  2YJ9 A;  3MHS A;  3BPM A;  1GMY A;  3P5W A;  2YJB A;  2PRE A;  1EWO A;  1X9Y A;  4XR7 A;  1NLJ A;  2AUZ A;  4AXL A;  1Y08 A;  3P5X A;  3RVV A;  1CPJ A;  1NL6 A;  4ZUX U;  3LFY A;  2AUX A;  1CS8 A;  1NB3 A;  1ITO A;  1GEC E;  1SNK A;  2XU5 A;  1QMY A;  4CZW A;  2PNS A;  2WBF X;  3OVZ A;  1YK8 A;  3C9E A;  1EF7 A;  3KSE A;  4QRV A;  2PAD A;  4BPV A;  3BOW A;  3S3Q A;  3PBH A;  3AI8 A;  1PIP A;  3BWK A;  3N3G A;  3IV2 A;  3PNR A;  1CSB B;  1CQD A;  4X6I A;  3V6C A;  2VHS A;  1AYU A;  2AYN A;  4RY2 A;  2NQD B;  2E01 A;  2ARY A;  4YYR A;  2FT2 A;  2IBI A;  3IEJ A;  1MDW A;  2HHN A;  3IMA A;  2E00 A;  1TU6 A;  1BGO A;  4W5B A;  3OF8 A;  4KLB A;  2G7Y A;  1YAL A;  5F02 A;  3TNX A;  2IPP B;  2CB5 A;  4QH6 A;  4CDF B;  2E03 A;  4P6E A;  1F2C A;  1PPD A;  5CVO B;  3BPF A;  2DC6 A;  4CDD B;  1U9W A;  1YVB A;  3QT4 A;  4G54 A;  4I07 A;  1ZIV A;  1VJV A;  3M99 A;  4MZS A;  5A24 A;  1K3B B;  1M6D A;  4N79 A;  2DJG B;  1BP4 A;  1CJL A;  2DZZ A;  3KFQ A;  1AYV A;  3RVW A;  2XU1 A;  2BDL A;  2ACT A;  4X6H A;  1PPO A;  4PAD A;  2YJ8 A;  3ERV A;  2GFO A;  3D6S A;  1Y4H A;  2AVW A;  2R9O A;  1CTE A;  1AU4 A;  1BY8 A;  1U9V A;  2FO5 A;  4I04 A;  4P6G A;  4QRG A;  1MHW A;  5K16 A;  3IHP A;  2YJC A;  4MZO A;  3KWZ A;  5J94 A;  2XU4 A;  3WXG A;  1PAD A;  3OIS A;  3WXE A;  4W5C A;  1PBH A;  2FQ9 A;  2PBH A;  1KFX L;  3I3T A;  3WXF A;  4N8W A;  2ATO A;  1KXR A;  1YT7 A;  5JH3 A;  5PAD A;  3V6E A;  2NQG A;  1KHQ A;  2FUD A;  1F2A A;  4XUI A;  4WA6 A;  1GLO A;  1Q6K A;  4FJC A;  2R6N A;  4FIP A;  1JQP A;  3DF0 A;  3ZUA A;  1U9Q X;  3B79 A;  4YYW A;  1NB5 A;  3I06 A;  3LXS A;  2E02 A;  2JQG R;  4YVA A;  4YYV A;  2R9N A;  1F29 A;  2FRA A;  4FK5 A;  3K9M A;  3H8C A;  3O0U A;  2DZY A;  3NHE A;  7PCK A;  2GHU A;  3N3K A;  2FYE A;  3HHI A;  4AXM A;  4BQV A;  3E1Z B;  4BS6 A;  3CH2 X;  9PAP A;  1PPN A;  1PXV A;  4MSX A;  1MS6 A;  2VHF A;  2DC7 A;  1PE6 A;  4I05 A;  3BC3 A;  1ICF A;  1ATK A;  1U9X A;  3F75 A;  2DC8 A;  3HD3 A;  2HXZ A;  1CVZ A;  3H6S A;  2P86 A;  2R9F A;  3KWB X;  4CDC B;  2AIM A;  4W4U A;  3O1G A;  2YJ2 A;  4X6J A;  2AU1 A;  3F5V A;  1AU0 A;  4YYU A;  2DCB A;  2FTD A;  3OVX A;  1MEM A;  2HD5 A;  2HH5 A;  1U5I A;  3S3R A;  3GCB A;  1VSN A;  2JQF R;  3USV A;  2OUL A;  1KFU L;  2F1G A;  2FRQ A;  3OF9 A;  5CHT A;  1DEU A;  3KKU A;  1IWD A;  2Y6E A;  3H8B A;  3MHH A;  4YV8 A;  2P0R A;  2C0Y A;  5CHV A;  8PCH A;  4YYQ A;  1NPZ A;  3H89 A;  3BCN A;  3PDF A;  5EGW A;  3H7D A;  4Q8H A;  2P7U A;  3P5V A;  4N4Z A;  3CBK A;  3QJ3 A;  2G8E A;  2R9M A;  2CIO A;  1QXP A;  5CVN B;  2G6D A;  1TL9 A;  3IUT A;  1CB5 A;  1AYW A;  1AIM A;  1GCB A;  3HWN A;  1QOL A;  2B1M A;  3KW9 A;  4OEM A;  2AS8 A;  3K8U A;  4YYS A;  3QSD A;  3KX1 A;  4PP2 E;  1F2B A;  2Y5B A;  2NQI A;  2O6X A;  3CH3 X;  2OP3 A;  1XKG A;  4DMX A;  2NQA A;  1A6R A;  2DCD A;  1O0E A;  3MTN A;  1AEC A;  1STF E;  5JA7 A;  1NQC A;  5FPW A;  2XU3 A;  1EWL A;  1KHP A;  4PP1 A;  1QDQ A;  1FH0 A;  3P5U A;  2DCC A;  4HWY A;  2DJF B;  1ZCM A;  2BDZ A;  2R9C A;  2OZ2 A;  3CBJ A;  1HUC B;  1ME3 A;  4K7C A;  4Q8G A;  4CDE B;  1MIR A;  3N4C A;  2G8J A;  2H7J A;  1CV8 A;  4DMY A;  1BQI A;  4OEL A;  5EF4 A;  4QRX A; 
#chains in the Genus database with same CATH topology
 3PW3 A;  3E9S A;  3PSE A;  1AU2 A;  1TLO A;  3U8E A;  4BS5 A;  2DC9 A;  1S4V A;  4BSQ A;  1YK7 A;  1EWM A;  1AU3 A;  1THE A;  3HHA A;  1POP A;  3IOQ A;  6PAD A;  1PCI A;  3MOR A;  2DCA A;  1EWP A;  1DF0 A;  2F7D A;  4QBB A;  4PI3 A;  2AYO A;  2BTW A;  3K24 A;  3PT2 A;  1PPP A;  3RVX A;  1SP4 B;  2B1N A;  5JZE A;  1ME4 A;  1MEG A;  5CVM A;  2YJ9 A;  3MHS A;  3BPM A;  1GMY A;  3P5W A;  4PT5 A;  2YJB A;  2PRE A;  1EWO A;  1X9Y A;  4XR7 A;  1NLJ A;  2AUZ A;  4AXL A;  1Y08 A;  3P5X A;  3RVV A;  1CPJ A;  1NL6 A;  4ZUX U;  3PHU A;  3LFY A;  2AUX A;  4BOU A;  1CS8 A;  4ZTB A;  1NB3 A;  3BY4 A;  1ITO A;  1GEC E;  1SNK A;  2XU5 A;  2AGA A;  4RNA A;  4OW0 A;  3IFU A;  1QMY A;  4CZW A;  2PNS A;  2WBF X;  3OVZ A;  3PHX A;  1YK8 A;  3C9E A;  1EF7 A;  3KSE A;  4QRV A;  2PAD A;  4BPV A;  3BOW A;  3S3Q A;  4HXD B;  3PBH A;  3AI8 A;  1PIP A;  3BWK A;  4MI7 A;  3N3G A;  3IV2 A;  3PNR A;  1CSB B;  1CQD A;  4X6I A;  3V6C A;  2VHS A;  1AYU A;  2AYN A;  4RY2 A;  2NQD B;  3BB7 A;  2E01 A;  4IP3 A;  2ARY A;  3MP2 A;  4YYR A;  2FT2 A;  2IBI A;  3PHW A;  3IEJ A;  1MDW A;  2HHN A;  3IMA A;  2E00 A;  1TU6 A;  1BGO A;  4W5B A;  3OF8 A;  4KLB A;  2G7Y A;  1YAL A;  5F02 A;  3TNX A;  2IPP B;  2CB5 A;  4QH6 A;  4CDF B;  2E03 A;  4P6E A;  1F2C A;  1PPD A;  5CVO B;  4A5U A;  3BPF A;  2DC6 A;  4CDD B;  1U9W A;  1YVB A;  3QT4 A;  3PRP A;  4G54 A;  4I07 A;  4RF0 A;  1ZIV A;  1VJV A;  3M99 A;  4MZS A;  5A24 A;  4GUA A;  1K3B B;  1M6D A;  4N79 A;  2DJG B;  1BP4 A;  1CJL A;  2HWK A;  2DZZ A;  3KFQ A;  1AYV A;  3RVW A;  2FE8 A;  3TMP A;  2XU1 A;  5KO3 A;  2BDL A;  2ACT A;  4X6H A;  1PPO A;  4PAD A;  2YJ8 A;  3ERV A;  2GFO A;  3D6S A;  1Y4H A;  2AVW A;  2R9O A;  1CTE A;  1AU4 A;  1BY8 A;  1U9V A;  1DKI A;  4BOQ A;  2FO5 A;  4I04 A;  4P6G A;  4QRG A;  1MHW A;  5K16 A;  3IHP A;  2YJC A;  4MZO A;  3KWZ A;  5J94 A;  2XU4 A;  3WXG A;  1PAD A;  3OIS A;  3WXE A;  4W5C A;  1PBH A;  2FQ9 A;  2PBH A;  1KFX L;  4MM3 B;  3I3T A;  3WXF A;  4N8W A;  4RKX A;  2ATO A;  5E6J A;  1KXR A;  1YT7 A;  5JH3 A;  5PAD A;  3V6E A;  2NQG A;  2J7Q A;  1KHQ A;  2FUD A;  1F2A A;  3B21 A;  4XUI A;  4WA6 A;  1GLO A;  1Q6K A;  4FJC A;  2DOS A;  2R6N A;  4FIP A;  1JQP A;  3DF0 A;  3ZUA A;  1U9Q X;  3B79 A;  4YYW A;  1YZB A;  3W30 A;  1NB5 A;  3I06 A;  3LXS A;  3BBA A;  2E02 A;  2JQG R;  2BU3 A;  4YVA A;  4YYV A;  2R9N A;  1F29 A;  2FRA A;  4FK5 A;  3K9M A;  3H8C A;  3O0U A;  2J7Q C;  3RNV A;  2DZY A;  3NHE A;  7PCK A;  2GHU A;  3N3K A;  2FYE A;  3HHI A;  4AXM A;  4BQV A;  3E1Z B;  4BS6 A;  3CH2 X;  9PAP A;  1PPN A;  1PXV A;  4D8I A;  4MSX A;  1MS6 A;  3O65 A;  2VHF A;  2DC7 A;  4REZ A;  1PE6 A;  4I05 A;  2JRI A;  3BC3 A;  4P16 A;  1ICF A;  1ATK A;  1U9X A;  3F75 A;  2DC8 A;  3HD3 A;  2HXZ A;  4OVZ B;  1CVZ A;  3H6S A;  2P86 A;  2R9F A;  3KWB X;  4CDC B;  2AIM A;  4W4U A;  3O1G A;  1UKF A;  2YJ2 A;  4X6J A;  2AU1 A;  3F5V A;  1AU0 A;  2Z84 A;  4YYU A;  2DCB A;  2UZJ A;  2FTD A;  3OVX A;  1MEM A;  2HD5 A;  2HH5 A;  1U5I A;  3S3R A;  3GCB A;  1VSN A;  2JQF R;  3USV A;  2OUL A;  1KFU L;  2F1G A;  2FRQ A;  3OF9 A;  4R3D A;  5CHT A;  1DEU A;  3KKU A;  1IWD A;  2Y6E A;  4OVZ A;  3H8B A;  3MHH A;  4YV8 A;  2P0R A;  1PVJ A;  2C0Y A;  5CHV A;  8PCH A;  4WUR A;  4YYQ A;  1NPZ A;  3H89 A;  3PRM A;  4D8E A;  3BCN A;  3PDF A;  4RF1 A;  5EGW A;  3H7D A;  4Q8H A;  3P5V A;  5EZQ A;  4N4Z A;  3CBK A;  3QJ3 A;  2G8E A;  2R9M A;  2CIO A;  1QXP A;  3MTV A;  5CVN B;  2G6D A;  1TL9 A;  3IUT A;  1CB5 A;  1AYW A;  1AIM A;  1GCB A;  3HWN A;  1QOL A;  2B1M A;  3KW9 A;  3MJ5 A;  4OEM A;  2AS8 A;  3K8U A;  4BOZ A;  4YYS A;  3QSD A;  4D8B A;  3KX1 A;  4PP2 E;  3TRK A;  4QRX A;  1F2B A;  2Y5B A;  2NQI A;  2O6X A;  3CH3 X;  5EZS A;  2OP3 A;  4IUM A;  3OQC A;  1XKG A;  4DMX A;  2NQA A;  1A6R A;  2DCD A;  1O0E A;  3MTN A;  1AEC A;  1STF E;  5JA7 A;  1NQC A;  5FPW A;  2XU3 A;  3W31 A;  1EWL A;  1KHP A;  4PP1 A;  1QDQ A;  1FH0 A;  3P5U A;  2DCC A;  4HWY A;  2DJF B;  2JTC A;  1ZCM A;  2BDZ A;  4XZX A;  2R9C A;  2OZ2 A;  3CBJ A;  1HUC B;  1ME3 A;  4K7C A;  4Q8G A;  2BTW B;  4M0W A;  1MIR A;  3N4C A;  4BOP A;  4CDE B;  3C0R A;  2G8J A;  2H7J A;  1CV8 A;  4DMY A;  1BQI A;  4OEL A;  5EF4 A;  4BOS A;  3ZNH A;  2P7U A; 
#chains in the Genus database with same CATH homology
 4NV7 A;  3PW3 A;  3LTW A;  1AU2 A;  1TLO A;  3U8E A;  4BS5 A;  2DC9 A;  1S4V A;  4BSQ A;  1YK7 A;  1EWM A;  1AU3 A;  1THE A;  3HHA A;  1POP A;  3IOQ A;  6PAD A;  1PCI A;  3MOR A;  2DCA A;  1EWP A;  1DF0 A;  2F7D A;  4QBB A;  4PI3 A;  2AYO A;  3K24 A;  1PPP A;  3RVX A;  1SP4 B;  2B1N A;  1ME4 A;  1MEG A;  5CVM A;  2YJ9 A;  3MHS A;  3BPM A;  1GMY A;  3P5W A;  2YJB A;  2PRE A;  1EWO A;  1X9Y A;  4XR7 A;  1NLJ A;  2AUZ A;  4AXL A;  1Y08 A;  3P5X A;  3RVV A;  1CPJ A;  1NL6 A;  4ZUX U;  3LFY A;  2AUX A;  1CS8 A;  1NB3 A;  1ITO A;  1GEC E;  1SNK A;  2XU5 A;  1QMY A;  4CZW A;  2PNS A;  2WBF X;  3OVZ A;  1YK8 A;  3C9E A;  1EF7 A;  3KSE A;  4QRV A;  2PAD A;  4BPV A;  3BOW A;  3S3Q A;  3PBH A;  3AI8 A;  1PIP A;  4BGF A;  3BWK A;  3N3G A;  3IV2 A;  3PNR A;  1CSB B;  1CQD A;  4X6I A;  3V6C A;  2VHS A;  1AYU A;  2AYN A;  4RY2 A;  2NQD B;  2E01 A;  2ARY A;  4YYR A;  1W6F A;  2FT2 A;  2IBI A;  3IEJ A;  1MDW A;  2HHN A;  3IMA A;  2E00 A;  1TU6 A;  1BGO A;  4W5B A;  3OF8 A;  4KLB A;  2G7Y A;  1YAL A;  5F02 A;  3TNX A;  2IPP B;  2CB5 A;  4QH6 A;  4CDF B;  2E03 A;  4P6E A;  1F2C A;  1PPD A;  5CVO B;  3BPF A;  2DC6 A;  4CDD B;  1U9W A;  1YVB A;  3QT4 A;  4G54 A;  4I07 A;  1ZIV A;  1VJV A;  3M99 A;  4MZS A;  5A24 A;  1K3B B;  1M6D A;  4N79 A;  2DJG B;  1BP4 A;  1CJL A;  2DZZ A;  3KFQ A;  1AYV A;  3RVW A;  2XU1 A;  2BDL A;  2ACT A;  4X6H A;  1PPO A;  4PAD A;  2YJ8 A;  3ERV A;  2GFO A;  1E2T A;  3D6S A;  1Y4H A;  2AVW A;  2R9O A;  1CTE A;  2VFB A;  1AU4 A;  1BY8 A;  1U9V A;  2FO5 A;  4I04 A;  4P6G A;  4QRG A;  1MHW A;  5K16 A;  3IHP A;  2YJC A;  4MZO A;  3KWZ A;  5J94 A;  2XU4 A;  3WXG A;  1PAD A;  3OIS A;  3WXE A;  4W5C A;  1PBH A;  2FQ9 A;  2PBH A;  4C5P A;  1KFX L;  3I3T A;  3WXF A;  4N8W A;  2ATO A;  1KXR A;  1YT7 A;  5JH3 A;  5PAD A;  3V6E A;  2NQG A;  1KHQ A;  2FUD A;  1F2A A;  4XUI A;  4WA6 A;  1GLO A;  1Q6K A;  4FJC A;  2R6N A;  4FIP A;  1JQP A;  3DF0 A;  3ZUA A;  1U9Q X;  3B79 A;  4YYW A;  1NB5 A;  3I06 A;  3LXS A;  2E02 A;  2JQG R;  4YVA A;  4YYV A;  2R9N A;  1F29 A;  2FRA A;  4FK5 A;  3K9M A;  3H8C A;  3O0U A;  2DZY A;  3NHE A;  1W5R A;  7PCK A;  2GHU A;  3N3K A;  2FYE A;  3HHI A;  4AXM A;  4BQV A;  3E1Z B;  4BS6 A;  3CH2 X;  9PAP A;  1PPN A;  1PXV A;  4MSX A;  1MS6 A;  2VHF A;  2DC7 A;  1PE6 A;  4I05 A;  3BC3 A;  1ICF A;  1ATK A;  1U9X A;  2VFC A;  3F75 A;  2DC8 A;  3HD3 A;  2HXZ A;  1CVZ A;  3H6S A;  2P86 A;  2R9F A;  3KWB X;  4CDC B;  2AIM A;  4W4U A;  3O1G A;  2YJ2 A;  4X6J A;  2AU1 A;  3F5V A;  1AU0 A;  4YYU A;  2DCB A;  2FTD A;  3OVX A;  1MEM A;  2HD5 A;  2HH5 A;  1U5I A;  3S3R A;  3GCB A;  1VSN A;  2JQF R;  3USV A;  2BSZ A;  2OUL A;  1KFU L;  1GX3 A;  2F1G A;  2FRQ A;  3OF9 A;  4B55 A;  5CHT A;  1DEU A;  3KKU A;  1IWD A;  2Y6E A;  3H8B A;  3MHH A;  4YV8 A;  2P0R A;  2C0Y A;  5CHV A;  3D9W A;  8PCH A;  4YYQ A;  1NPZ A;  3H89 A;  3BCN A;  3PDF A;  5EGW A;  3H7D A;  4Q8H A;  3P5V A;  4N4Z A;  3CBK A;  3QJ3 A;  2G8E A;  2R9M A;  2CIO A;  1QXP A;  5CVN B;  2G6D A;  1TL9 A;  3IUT A;  1W4T A;  1CB5 A;  1AYW A;  1AIM A;  1GCB A;  3HWN A;  1QOL A;  2B1M A;  3KW9 A;  4OEM A;  2AS8 A;  3K8U A;  4YYS A;  3QSD A;  3KX1 A;  4PP2 E;  4QRX A;  1F2B A;  2Y5B A;  2NQI A;  2O6X A;  3CH3 X;  2OP3 A;  1XKG A;  4DMX A;  2NQA A;  1A6R A;  2DCD A;  1O0E A;  3MTN A;  1AEC A;  1STF E;  5JA7 A;  1NQC A;  4NV8 A;  4GUZ A;  5FPW A;  2XU3 A;  1EWL A;  1KHP A;  4PP1 A;  1QDQ A;  1FH0 A;  3P5U A;  2DCC A;  4HWY A;  2DJF B;  1ZCM A;  2BDZ A;  2R9C A;  2OZ2 A;  3CBJ A;  1HUC B;  1ME3 A;  4K7C A;  4Q8G A;  4CDE B;  1MIR A;  3N4C A;  2G8J A;  2H7J A;  1CV8 A;  4DMY A;  1BQI A;  4OEL A;  5EF4 A;  2P7U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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