3KKUA

Cruzain in complex with a non-covalent ligand
Total Genus 70
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
70
sequence length
215
structure length
214
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma cruzi
molecule keywords Cruzipain
total genus 70
structure length 214
sequence length 215
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2009-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3kkuA00
4QH6A 4BPVA 3U8EA 2R9NA 1U9VA 3QJ3A 3K9MA 3KWZA 2P86A 1AYWA 1PPNA 1F2BA 3BPFA 1NPZA 2AUXA 1CPJA 3QT4A 3E1ZB 1CB5A 3K24A 4K7CA 2JQGR 1U5IA 2XU4A 1IWDA 1TLOA 3K8UA 3KKUA 2O6XA 2ARYA 2XU3A 4X6JA 1FH0A 2WBFX 4YV8A 1ZCMA 1KHPA 4PI3A 2HHNA 5CVOB 1KHQA 2VHFA 3N4CA 1THEA 3O0UA 2AU1A 4I07A 2F1GA 4FK5A 2R9OA 4N4ZA 1GLOA 2FTDA 3C9EA 3OF8A 4QRXA 2DC9A 2YJ9A 2FYEA 2NQDB 4QRVA 3OISA 3HHIA 1MS6A 1AIMA 1AU0A 2PREA 3D6SA 3P5XA 4BSQA 1QMYA 4AXLA 2R9CA 1NQCA 3H8CA 4W5CA 3BOWA 3PW3A 1ICFA 2FT2A 1PIPA 1PADA 1TL9A 5K16A 4FIPA 2R9MA 3P5VA 1KFUL 1GCBA 3IMAA 2CIOA 1KFXL 1PPOA 9PAPA 1CVZA 5JA7A 2FO5A 4MZOA 2YJ8A 3V6CA 2XU1A 3LXSA 1BQIA 2DZYA 3QSDA 3PBHA 1JQPA 3IUTA 2OZ2A 4BQVA 4XR7A 1EWLA 2VHSA 3F75A 4YYQA 4CDEB 1BP4A 4QRGA 1PPDA 2FRQA 2G8EA 3LFYA 4YYRA 2YJ2A 3RVWA 2P7UA 1SP4B 2DCAA 3OF9A 1PE6A 4P6GA 4XUIA 2BDLA 3BCNA 7PCKA 1ITOA 3MTNA 2E02A 3P5WA 4X6HA 1EWOA 4CZWA 1U9QX 3HWNA 2OP3A 1AU3A 2HH5A 2Y5BA 4I05A 1QOLA 1XKGA 4YVAA 1QXPA 4MZSA 3IOQA 3CH2X 3H8BA 3BC3A 5CHTA 4DMYA 3AI8A 4YYWA 1PBHA 2HXZA 2C0YA 2AYNA 4YYSA 1KXRA 1GMYA 3RVXA 1YVBA 1YK7A 4YYVA 1MEMA 4G54A 1STFE 1YT7A 1NB5A 3V6EA 1VSNA 3O1GA 4N8WA 3N3KA 4N79A 3MORA 2AIMA 2PBHA 4X6IA 1ME4A 2DCDA 4PP2E 3S3RA 3H6SA 2F7DA 2CB5A 1GECE 2JQFR 2YJCA 1VJVA 4I04A 2FRAA 1EWPA 2PADA 3N3GA 4WA6A 3USVA 1K3BB 4YYUA 1CSBB 4QBBA 3IEJA 2AVWA 4BS6A 5CHVA 1Y4HA 1O0EA 3GCBA 3IV2A 3CBKA 3H7DA 2NQAA 2P0RA 4P6EA 1X9YA 5PADA 1AECA 1F2AA 1CV8A 3KSEA 4CDCB 2DCBA 3IHPA 1Y08A 4AXMA 1ZIVA 2B1MA 1CJLA 4BS5A 2OULA 1TU6A 2DJGB 1PPPA 2XU5A 3M99A 4HWYA 5EF4A 1YK8A 2G7YA 5JH3A 2R6NA 1PXVA 3HHAA 2ATOA 1CS8A 2DC7A 1U9XA 2FUDA 1ATKA 3DF0A 1POPA 3BWKA 3F5VA 5FPWA 1EWMA 2IPPB 1Q6KA 3ZUAA 3CH3X 3MHSA 1F29A 2DZZA 3WXGA 4Q8HA 3ERVA 1CQDA 2AS8A 4Q8GA 1QDQA 2G6DA 3B79A 3HD3A 4W5BA 1NB3A 5A24A 1AYVA 3I3TA 4W4UA 1A6RA 3WXEA 2DC8A 2B1NA 3NHEA 1MIRA 2R9FA 1EF7A 3TNXA 4FJCA 5EGWA 2FQ9A 4ZUXU 4PADA 1AYUA 4MSXA 6PADA 8PCHA 3KWBX 2E01A 3BPMA 4OEMA 4KLBA 5F02A 1DF0A 1F2CA 1YALA 3KFQA 3PNRA 5CVMA 4PP1A 1NLJA 3WXFA 2AUZA 2DJFB 3H89A 3OVXA 2G8JA 1AU2A 1S4VA 1HUCB 2NQGA 5CVNB 1SNKA 1NL6A 4CDDB 1PCIA 3OVZA 1U9WA 4RY2A 3P5UA 3MHHA 1MHWA 2PNSA 2HD5A 2BDZA 3KX1A 4OELA 3CBJA 1M6DA 4DMXA 4CDFB 2E03A 3I06A 1AU4A 2Y6EA 2ACTA 5J94A 2DCCA 2GHUA 3S3QA 1ME3A 2E00A 3RVVA 1DEUA 2H7JA 2YJBA 3KW9A 2AYOA 2DC6A 2IBIA 1BY8A 1BGOA 1MDWA 3PDFA 2GFOA 2NQIA 1MEGA 1CTEA
chains in the Genus database with same CATH superfamily
4QH6A 4BPVA 3U8EA 2R9NA 1U9VA 3QJ3A 3PRMA 3K9MA 3KWZA 2P86A 1AYWA 1PPNA 1F2BA 3BPFA 1NPZA 2AUXA 1CPJA 3QT4A 3E1ZB 1CB5A 3K24A 4K7CA 2JQGR 1U5IA 4D8BA 2XU4A 4OW0A 1IWDA 1TLOA 3K8UA 3MJ5A 3KKUA 4BOQA 2O6XA 2ARYA 2XU3A 4X6JA 1FH0A 2WBFX 4YV8A 2J7QA 1ZCMA 1KHPA 4PI3A 4BOSA 2HHNA 4IUMA 5CVOB 1KHQA 2VHFA 3N4CA 1THEA 5EZQA 3O0UA 2AU1A 3PHWA 4I07A 4IP3A 2F1GA 4FK5A 2R9OA 2UZJA 4P16A 4N4ZA 1GLOA 2FTDA 4A5UA 3C9EA 1YZBA 3OF8A 4QRXA 2DC9A 2YJ9A 2FYEA 2NQDB 4QRVA 3OISA 3HHIA 4HXDB 1MS6A 1PVJA 1AIMA 3D6SA 1AU0A 2PREA 2Z84A 3P5XA 4BSQA 1QMYA 4AXLA 2R9CA 1NQCA 3H8CA 4W5CA 3BOWA 3BBAA 3ZNHA 3PW3A 1ICFA 4RF1A 2FT2A 1PIPA 1PADA 1TL9A 5K16A 4FIPA 2R9MA 3P5VA 1KFUL 3E9SA 1GCBA 3IMAA 2CIOA 3PHXA 1KFXL 1PPOA 3MTVA 9PAPA 1CVZA 5JA7A 2FO5A 4MZOA 2YJ8A 3V6CA 2XU1A 3LXSA 1BQIA 4XZXA 4OVZA 4GUAA 2DZYA 3TRKA 3QSDA 3PBHA 1JQPA 3IUTA 2OZ2A 4BQVA 4XR7A 1EWLA 2VHSA 3F75A 4YYQA 3RNVA 4CDEB 1BP4A 4QRGA 4WURA 3OQCA 1PPDA 2FRQA 2G8EA 3LFYA 4YYRA 2YJ2A 3RVWA 2P7UA 1SP4B 2DCAA 4ZTBA 3OF9A 1PE6A 4P6GA 4XUIA 2BDLA 3BCNA 7PCKA 1ITOA 3MTNA 1DKIA 3PT2A 4MI7A 2E02A 3P5WA 4X6HA 1EWOA 3IFUA 5KO3A 3PHUA 4CZWA 1U9QX 3HWNA 4RKXA 2OP3A 1AU3A 1UKFA 2HH5A 2Y5BA 4I05A 2AGAA 1QOLA 1XKGA 4YVAA 1QXPA 4MZSA 3IOQA 3CH2X 3H8BA 3BC3A 5CHTA 4DMYA 3AI8A 4BOUA 4YYWA 1PBHA 4BOPA 2HXZA 2C0YA 2AYNA 4YYSA 1KXRA 1GMYA 3RVXA 1YVBA 3BY4A 1YK7A 4YYVA 1MEMA 4G54A 1STFE 1YT7A 1NB5A 2BU3A 3V6EA 1VSNA 3O1GA 4N8WA 3N3KA 4N79A 3MORA 2AIMA 2PBHA 4X6IA 1ME4A 2DCDA 4PP2E 3S3RA 3W31A 3H6SA 2F7DA 2DOSA 2CB5A 1GECE 2JQFR 2YJCA 1VJVA 4I04A 2FRAA 1EWPA 2PADA 3N3GA 4WA6A 3USVA 1K3BB 4YYUA 1CSBB 4QBBA 3IEJA 2AVWA 4BS6A 5CHVA 1Y4HA 4RF0A 1O0EA 3GCBA 3IV2A 3CBKA 3H7DA 2NQAA 2HWKA 2P0RA 4PT5A 3W30A 4P6EA 1X9YA 5PADA 3C0RA 1AECA 1F2AA 1CV8A 3KSEA 4CDCB 2DCBA 3IHPA 1Y08A 4AXMA 1ZIVA 3O65A 2B1MA 1CJLA 2FE8A 4BS5A 3B21A 2OULA 1TU6A 2DJGB 1PPPA 2XU5A 3M99A 4D8IA 4HWYA 5EF4A 1YK8A 2G7YA 5JH3A 2R6NA 1PXVA 3HHAA 3PRPA 2ATOA 1CS8A 2DC7A 2FUDA 1U9XA 1ATKA 3DF0A 1POPA 3BWKA 3F5VA 5FPWA 1EWMA 2IPPB 1Q6KA 3ZUAA 3CH3X 3MHSA 4MM3B 3TMPA 1F29A 2DZZA 3WXGA 4Q8HA 3ERVA 1CQDA 2AS8A 4Q8GA 1QDQA 2BTWB 2JTCA 2G6DA 3B79A 3HD3A 4RNAA 1NB3A 4W5BA 5A24A 1AYVA 3I3TA 4W4UA 5EZSA 1A6RA 2BTWA 3MP2A 3WXEA 2DC8A 2B1NA 3NHEA 1MIRA 2R9FA 1EF7A 4R3DA 3TNXA 4FJCA 5EGWA 2FQ9A 4ZUXU 4PADA 1AYUA 4D8EA 4MSXA 6PADA 8PCHA 3KWBX 2E01A 3BPMA 2J7QC 4KLBA 4OEMA 5F02A 1DF0A 1F2CA 1YALA 3KFQA 3PNRA 5CVMA 4PP1A 1NLJA 3WXFA 2AUZA 2DJFB 3H89A 3OVXA 2G8JA 1AU2A 1S4VA 1HUCB 2NQGA 5CVNB 1SNKA 1NL6A 4CDDB 1PCIA 3OVZA 1U9WA 4RY2A 3P5UA 5E6JA 3MHHA 1MHWA 2PNSA 2HD5A 4REZA 2BDZA 3KX1A 4OELA 3CBJA 1M6DA 4DMXA 4CDFB 2E03A 3I06A 1AU4A 2Y6EA 2ACTA 5J94A 2DCCA 2JRIA 4OVZB 2GHUA 3S3QA 3PSEA 1ME3A 3BB7A 2E00A 4M0WA 3RVVA 1DEUA 2H7JA 2YJBA 3KW9A 2AYOA 2DC6A 2IBIA 1BY8A 1BGOA 1MDWA 3PDFA 5JZEA 2GFOA 2NQIA 4BOZA 1MEGA 1CTEA
chains in the Genus database with same CATH topology
4QH6A 4BGFA 4BPVA 3U8EA 2R9NA 1U9VA 3QJ3A 3K9MA 3KWZA 2P86A 1AYWA 1PPNA 1F2BA 3BPFA 1NPZA 2AUXA 1CPJA 4NV7A 3QT4A 3E1ZB 1CB5A 3K24A 4K7CA 2JQGR 1U5IA 2XU4A 1IWDA 1TLOA 3K8UA 3KKUA 2O6XA 2ARYA 2XU3A 4X6JA 1FH0A 2WBFX 4YV8A 1ZCMA 1KHPA 4PI3A 2HHNA 5CVOB 1KHQA 2VHFA 3N4CA 1THEA 3O0UA 2AU1A 4I07A 2F1GA 4FK5A 2R9OA 4N4ZA 1GLOA 2FTDA 3C9EA 3OF8A 4QRXA 2DC9A 2YJ9A 2FYEA 2NQDB 4QRVA 3OISA 3HHIA 1MS6A 1AIMA 1AU0A 2PREA 3D6SA 3P5XA 4BSQA 1QMYA 4AXLA 2R9CA 3LTWA 1NQCA 3H8CA 4W5CA 3BOWA 3PW3A 1ICFA 2FT2A 1PIPA 1PADA 1TL9A 5K16A 4FIPA 2R9MA 3P5VA 1KFUL 1GCBA 3IMAA 3D9WA 2CIOA 1KFXL 1PPOA 9PAPA 1CVZA 5JA7A 2FO5A 4MZOA 2YJ8A 3V6CA 2XU1A 3LXSA 1BQIA 2DZYA 3QSDA 3PBHA 1JQPA 3IUTA 2OZ2A 4BQVA 4XR7A 1EWLA 2VHSA 3F75A 4YYQA 4CDEB 1BP4A 4QRGA 1PPDA 2FRQA 2G8EA 3LFYA 4YYRA 2YJ2A 3RVWA 2P7UA 1SP4B 2DCAA 4C5PA 3OF9A 1PE6A 4P6GA 4XUIA 2BDLA 3BCNA 7PCKA 1ITOA 3MTNA 2E02A 3P5WA 4X6HA 1EWOA 4NV8A 4CZWA 1U9QX 3HWNA 2OP3A 1AU3A 2BSZA 2HH5A 2Y5BA 4I05A 1QOLA 1XKGA 4YVAA 1QXPA 4MZSA 3IOQA 3CH2X 3H8BA 3BC3A 5CHTA 4DMYA 3AI8A 4YYWA 1PBHA 2HXZA 2C0YA 2AYNA 4YYSA 1KXRA 1GMYA 3RVXA 1YVBA 1YK7A 4YYVA 1MEMA 4G54A 1STFE 1YT7A 1NB5A 1W5RA 3V6EA 2VFCA 1VSNA 3O1GA 4N8WA 3N3KA 4N79A 3MORA 2AIMA 2PBHA 4X6IA 1ME4A 2DCDA 4B55A 4PP2E 3S3RA 3H6SA 2F7DA 2CB5A 1GECE 2JQFR 2YJCA 1VJVA 4I04A 2FRAA 1EWPA 2PADA 3N3GA 1GX3A 4WA6A 3USVA 1K3BB 4YYUA 1CSBB 4QBBA 3IEJA 2AVWA 4BS6A 5CHVA 1Y4HA 1O0EA 1W6FA 3GCBA 3IV2A 3CBKA 3H7DA 2NQAA 2P0RA 4P6EA 2VFBA 1X9YA 5PADA 1AECA 1F2AA 1CV8A 3KSEA 4CDCB 2DCBA 3IHPA 1Y08A 4AXMA 1ZIVA 2B1MA 1CJLA 4BS5A 2OULA 1TU6A 2DJGB 1PPPA 2XU5A 3M99A 4HWYA 5EF4A 1YK8A 2G7YA 5JH3A 2R6NA 1PXVA 3HHAA 2ATOA 1CS8A 2DC7A 1U9XA 2FUDA 1ATKA 3DF0A 1POPA 3BWKA 3F5VA 5FPWA 1EWMA 2IPPB 1Q6KA 3ZUAA 3CH3X 3MHSA 1F29A 2DZZA 3WXGA 4Q8HA 3ERVA 1CQDA 2AS8A 4Q8GA 1QDQA 2G6DA 3B79A 3HD3A 4W5BA 1NB3A 5A24A 1AYVA 3I3TA 4W4UA 1A6RA 3WXEA 2DC8A 2B1NA 3NHEA 1MIRA 2R9FA 1EF7A 3TNXA 1W4TA 4FJCA 5EGWA 2FQ9A 4ZUXU 4PADA 1AYUA 4MSXA 6PADA 8PCHA 3KWBX 2E01A 3BPMA 4OEMA 4KLBA 5F02A 1DF0A 1F2CA 1YALA 3KFQA 3PNRA 5CVMA 4PP1A 1NLJA 3WXFA 2AUZA 1E2TA 2DJFB 3H89A 3OVXA 2G8JA 1AU2A 1S4VA 1HUCB 2NQGA 5CVNB 1SNKA 1NL6A 4CDDB 1PCIA 3OVZA 1U9WA 4RY2A 3P5UA 3MHHA 1MHWA 2PNSA 2HD5A 2BDZA 3KX1A 4OELA 3CBJA 1M6DA 4DMXA 4CDFB 2E03A 3I06A 1AU4A 2Y6EA 2ACTA 5J94A 2DCCA 2GHUA 3S3QA 4GUZA 1ME3A 2E00A 3RVVA 1DEUA 2H7JA 2YJBA 3KW9A 2AYOA 2DC6A 2IBIA 1BY8A 1BGOA 1MDWA 3PDFA 2GFOA 2NQIA 1MEGA 1CTEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QH6 A;  4BPV A;  3U8E A;  2R9N A;  1U9V A;  3QJ3 A;  3K9M A;  3KWZ A;  2P86 A;  1AYW A;  1PPN A;  1F2B A;  3BPF A;  1NPZ A;  2AUX A;  1CPJ A;  3QT4 A;  3E1Z B;  1CB5 A;  3K24 A;  4K7C A;  2JQG R;  1U5I A;  2XU4 A;  1IWD A;  1TLO A;  3K8U A;  3KKU A;  2O6X A;  2ARY A;  2XU3 A;  4X6J A;  1FH0 A;  2WBF X;  4YV8 A;  1ZCM A;  1KHP A;  4PI3 A;  2HHN A;  5CVO B;  1KHQ A;  2VHF A;  3N4C A;  1THE A;  3O0U A;  2AU1 A;  4I07 A;  2F1G A;  4FK5 A;  2R9O A;  4N4Z A;  1GLO A;  2FTD A;  3C9E A;  3OF8 A;  4QRX A;  2DC9 A;  2YJ9 A;  2FYE A;  2NQD B;  4QRV A;  3OIS A;  3HHI A;  1MS6 A;  1AIM A;  1AU0 A;  2PRE A;  3D6S A;  3P5X A;  4BSQ A;  1QMY A;  4AXL A;  2R9C A;  1NQC A;  3H8C A;  4W5C A;  3BOW A;  3PW3 A;  1ICF A;  2FT2 A;  1PIP A;  1PAD A;  1TL9 A;  5K16 A;  4FIP A;  2R9M A;  3P5V A;  1KFU L;  1GCB A;  3IMA A;  2CIO A;  1KFX L;  1PPO A;  9PAP A;  1CVZ A;  5JA7 A;  2FO5 A;  4MZO A;  2YJ8 A;  3V6C A;  2XU1 A;  3LXS A;  1BQI A;  2DZY A;  3QSD A;  3PBH A;  1JQP A;  3IUT A;  2OZ2 A;  4BQV A;  4XR7 A;  1EWL A;  2VHS A;  3F75 A;  4YYQ A;  4CDE B;  1BP4 A;  4QRG A;  1PPD A;  2FRQ A;  2G8E A;  3LFY A;  4YYR A;  2YJ2 A;  3RVW A;  2P7U A;  1SP4 B;  2DCA A;  3OF9 A;  1PE6 A;  4P6G A;  4XUI A;  2BDL A;  3BCN A;  7PCK A;  1ITO A;  3MTN A;  2E02 A;  3P5W A;  4X6H A;  1EWO A;  4CZW A;  1U9Q X;  3HWN A;  2OP3 A;  1AU3 A;  2HH5 A;  2Y5B A;  4I05 A;  1QOL A;  1XKG A;  4YVA A;  1QXP A;  4MZS A;  3IOQ A;  3CH2 X;  3H8B A;  3BC3 A;  5CHT A;  4DMY A;  3AI8 A;  4YYW A;  1PBH A;  2HXZ A;  2C0Y A;  2AYN A;  4YYS A;  1KXR A;  1GMY A;  3RVX A;  1YVB A;  1YK7 A;  4YYV A;  1MEM A;  4G54 A;  1STF E;  1YT7 A;  1NB5 A;  3V6E A;  1VSN A;  3O1G A;  4N8W A;  3N3K A;  4N79 A;  3MOR A;  2AIM A;  2PBH A;  4X6I A;  1ME4 A;  2DCD A;  4PP2 E;  3S3R A;  3H6S A;  2F7D A;  2CB5 A;  1GEC E;  2JQF R;  2YJC A;  1VJV A;  4I04 A;  2FRA A;  1EWP A;  2PAD A;  3N3G A;  4WA6 A;  3USV A;  1K3B B;  4YYU A;  1CSB B;  4QBB A;  3IEJ A;  2AVW A;  4BS6 A;  5CHV A;  1Y4H A;  1O0E A;  3GCB A;  3IV2 A;  3CBK A;  3H7D A;  2NQA A;  2P0R A;  4P6E A;  1X9Y A;  5PAD A;  1AEC A;  1F2A A;  1CV8 A;  3KSE A;  4CDC B;  2DCB A;  3IHP A;  1Y08 A;  4AXM A;  1ZIV A;  2B1M A;  1CJL A;  4BS5 A;  2OUL A;  1TU6 A;  2DJG B;  1PPP A;  2XU5 A;  3M99 A;  4HWY A;  5EF4 A;  1YK8 A;  2G7Y A;  5JH3 A;  2R6N A;  1PXV A;  3HHA A;  2ATO A;  1CS8 A;  2DC7 A;  1U9X A;  2FUD A;  1ATK A;  3DF0 A;  1POP A;  3BWK A;  3F5V A;  5FPW A;  1EWM A;  2IPP B;  1Q6K A;  3ZUA A;  3CH3 X;  3MHS A;  1F29 A;  2DZZ A;  3WXG A;  4Q8H A;  3ERV A;  1CQD A;  2AS8 A;  4Q8G A;  1QDQ A;  2G6D A;  3B79 A;  3HD3 A;  4W5B A;  1NB3 A;  5A24 A;  1AYV A;  3I3T A;  4W4U A;  1A6R A;  3WXE A;  2DC8 A;  2B1N A;  3NHE A;  1MIR A;  2R9F A;  1EF7 A;  3TNX A;  4FJC A;  5EGW A;  2FQ9 A;  4ZUX U;  4PAD A;  1AYU A;  4MSX A;  6PAD A;  8PCH A;  3KWB X;  2E01 A;  3BPM A;  4OEM A;  4KLB A;  5F02 A;  1DF0 A;  1F2C A;  1YAL A;  3KFQ A;  3PNR A;  5CVM A;  4PP1 A;  1NLJ A;  3WXF A;  2AUZ A;  2DJF B;  3H89 A;  3OVX A;  2G8J A;  1AU2 A;  1S4V A;  1HUC B;  2NQG A;  5CVN B;  1SNK A;  1NL6 A;  4CDD B;  1PCI A;  3OVZ A;  1U9W A;  4RY2 A;  3P5U A;  3MHH A;  1MHW A;  2PNS A;  2HD5 A;  2BDZ A;  3KX1 A;  4OEL A;  3CBJ A;  1M6D A;  4DMX A;  4CDF B;  2E03 A;  3I06 A;  1AU4 A;  2Y6E A;  2ACT A;  5J94 A;  2DCC A;  2GHU A;  3S3Q A;  1ME3 A;  2E00 A;  3RVV A;  1DEU A;  2H7J A;  2YJB A;  3KW9 A;  2AYO A;  2DC6 A;  2IBI A;  1BY8 A;  1BGO A;  1MDW A;  3PDF A;  2GFO A;  2NQI A;  1MEG A;  1CTE A; 
#chains in the Genus database with same CATH topology
 4QH6 A;  4BPV A;  3U8E A;  2R9N A;  1U9V A;  3QJ3 A;  3PRM A;  3K9M A;  3KWZ A;  2P86 A;  1AYW A;  1PPN A;  1F2B A;  3BPF A;  1NPZ A;  2AUX A;  1CPJ A;  3QT4 A;  3E1Z B;  1CB5 A;  3K24 A;  4K7C A;  2JQG R;  1U5I A;  4D8B A;  2XU4 A;  4OW0 A;  1IWD A;  1TLO A;  3K8U A;  3MJ5 A;  3KKU A;  4BOQ A;  2O6X A;  2ARY A;  2XU3 A;  4X6J A;  1FH0 A;  2WBF X;  4YV8 A;  2J7Q A;  1ZCM A;  1KHP A;  4PI3 A;  4BOS A;  2HHN A;  4IUM A;  5CVO B;  1KHQ A;  2VHF A;  3N4C A;  1THE A;  5EZQ A;  3O0U A;  2AU1 A;  3PHW A;  4I07 A;  4IP3 A;  2F1G A;  4FK5 A;  2R9O A;  2UZJ A;  4P16 A;  4N4Z A;  1GLO A;  2FTD A;  4A5U A;  3C9E A;  1YZB A;  3OF8 A;  4QRX A;  2DC9 A;  2YJ9 A;  2FYE A;  2NQD B;  4QRV A;  3OIS A;  3HHI A;  4HXD B;  1MS6 A;  1PVJ A;  1AIM A;  3D6S A;  1AU0 A;  2PRE A;  2Z84 A;  3P5X A;  4BSQ A;  1QMY A;  4AXL A;  2R9C A;  1NQC A;  3H8C A;  4W5C A;  3BOW A;  3BBA A;  3ZNH A;  3PW3 A;  1ICF A;  4RF1 A;  2FT2 A;  1PIP A;  1PAD A;  1TL9 A;  5K16 A;  4FIP A;  2R9M A;  3P5V A;  1KFU L;  3E9S A;  1GCB A;  3IMA A;  2CIO A;  3PHX A;  1KFX L;  1PPO A;  3MTV A;  9PAP A;  1CVZ A;  5JA7 A;  2FO5 A;  4MZO A;  2YJ8 A;  3V6C A;  2XU1 A;  3LXS A;  1BQI A;  4XZX A;  4OVZ A;  4GUA A;  2DZY A;  3TRK A;  3QSD A;  3PBH A;  1JQP A;  3IUT A;  2OZ2 A;  4BQV A;  4XR7 A;  1EWL A;  2VHS A;  3F75 A;  4YYQ A;  3RNV A;  4CDE B;  1BP4 A;  4QRG A;  4WUR A;  3OQC A;  1PPD A;  2FRQ A;  2G8E A;  3LFY A;  4YYR A;  2YJ2 A;  3RVW A;  2P7U A;  1SP4 B;  2DCA A;  4ZTB A;  3OF9 A;  1PE6 A;  4P6G A;  4XUI A;  2BDL A;  3BCN A;  7PCK A;  1ITO A;  3MTN A;  1DKI A;  3PT2 A;  4MI7 A;  2E02 A;  3P5W A;  4X6H A;  1EWO A;  3IFU A;  5KO3 A;  3PHU A;  4CZW A;  1U9Q X;  3HWN A;  4RKX A;  2OP3 A;  1AU3 A;  1UKF A;  2HH5 A;  2Y5B A;  4I05 A;  2AGA A;  1QOL A;  1XKG A;  4YVA A;  1QXP A;  4MZS A;  3IOQ A;  3CH2 X;  3H8B A;  3BC3 A;  5CHT A;  4DMY A;  3AI8 A;  4BOU A;  4YYW A;  1PBH A;  4BOP A;  2HXZ A;  2C0Y A;  2AYN A;  4YYS A;  1KXR A;  1GMY A;  3RVX A;  1YVB A;  3BY4 A;  1YK7 A;  4YYV A;  1MEM A;  4G54 A;  1STF E;  1YT7 A;  1NB5 A;  2BU3 A;  3V6E A;  1VSN A;  3O1G A;  4N8W A;  3N3K A;  4N79 A;  3MOR A;  2AIM A;  2PBH A;  4X6I A;  1ME4 A;  2DCD A;  4PP2 E;  3S3R A;  3W31 A;  3H6S A;  2F7D A;  2DOS A;  2CB5 A;  1GEC E;  2JQF R;  2YJC A;  1VJV A;  4I04 A;  2FRA A;  1EWP A;  2PAD A;  3N3G A;  4WA6 A;  3USV A;  1K3B B;  4YYU A;  1CSB B;  4QBB A;  3IEJ A;  2AVW A;  4BS6 A;  5CHV A;  1Y4H A;  4RF0 A;  1O0E A;  3GCB A;  3IV2 A;  3CBK A;  3H7D A;  2NQA A;  2HWK A;  2P0R A;  4PT5 A;  3W30 A;  4P6E A;  1X9Y A;  5PAD A;  3C0R A;  1AEC A;  1F2A A;  1CV8 A;  3KSE A;  4CDC B;  2DCB A;  3IHP A;  1Y08 A;  4AXM A;  1ZIV A;  3O65 A;  2B1M A;  1CJL A;  2FE8 A;  4BS5 A;  3B21 A;  2OUL A;  1TU6 A;  2DJG B;  1PPP A;  2XU5 A;  3M99 A;  4D8I A;  4HWY A;  5EF4 A;  1YK8 A;  2G7Y A;  5JH3 A;  2R6N A;  1PXV A;  3HHA A;  3PRP A;  2ATO A;  1CS8 A;  2DC7 A;  2FUD A;  1U9X A;  1ATK A;  3DF0 A;  1POP A;  3BWK A;  3F5V A;  5FPW A;  1EWM A;  2IPP B;  1Q6K A;  3ZUA A;  3CH3 X;  3MHS A;  4MM3 B;  3TMP A;  1F29 A;  2DZZ A;  3WXG A;  4Q8H A;  3ERV A;  1CQD A;  2AS8 A;  4Q8G A;  1QDQ A;  2BTW B;  2JTC A;  2G6D A;  3B79 A;  3HD3 A;  4RNA A;  1NB3 A;  4W5B A;  5A24 A;  1AYV A;  3I3T A;  4W4U A;  5EZS A;  1A6R A;  2BTW A;  3MP2 A;  3WXE A;  2DC8 A;  2B1N A;  3NHE A;  1MIR A;  2R9F A;  1EF7 A;  4R3D A;  3TNX A;  4FJC A;  5EGW A;  2FQ9 A;  4ZUX U;  4PAD A;  1AYU A;  4D8E A;  4MSX A;  6PAD A;  8PCH A;  3KWB X;  2E01 A;  3BPM A;  2J7Q C;  4KLB A;  4OEM A;  5F02 A;  1DF0 A;  1F2C A;  1YAL A;  3KFQ A;  3PNR A;  5CVM A;  4PP1 A;  1NLJ A;  3WXF A;  2AUZ A;  2DJF B;  3H89 A;  3OVX A;  2G8J A;  1AU2 A;  1S4V A;  1HUC B;  2NQG A;  5CVN B;  1SNK A;  1NL6 A;  4CDD B;  1PCI A;  3OVZ A;  1U9W A;  4RY2 A;  3P5U A;  5E6J A;  3MHH A;  1MHW A;  2PNS A;  2HD5 A;  4REZ A;  2BDZ A;  3KX1 A;  4OEL A;  3CBJ A;  1M6D A;  4DMX A;  4CDF B;  2E03 A;  3I06 A;  1AU4 A;  2Y6E A;  2ACT A;  5J94 A;  2DCC A;  2JRI A;  4OVZ B;  2GHU A;  3S3Q A;  3PSE A;  1ME3 A;  3BB7 A;  2E00 A;  4M0W A;  3RVV A;  1DEU A;  2H7J A;  2YJB A;  3KW9 A;  2AYO A;  2DC6 A;  2IBI A;  1BY8 A;  1BGO A;  1MDW A;  3PDF A;  5JZE A;  2GFO A;  2NQI A;  4BOZ A;  1MEG A;  1CTE A; 
#chains in the Genus database with same CATH homology
 4QH6 A;  4BGF A;  4BPV A;  3U8E A;  2R9N A;  1U9V A;  3QJ3 A;  3K9M A;  3KWZ A;  2P86 A;  1AYW A;  1PPN A;  1F2B A;  3BPF A;  1NPZ A;  2AUX A;  1CPJ A;  4NV7 A;  3QT4 A;  3E1Z B;  1CB5 A;  3K24 A;  4K7C A;  2JQG R;  1U5I A;  2XU4 A;  1IWD A;  1TLO A;  3K8U A;  3KKU A;  2O6X A;  2ARY A;  2XU3 A;  4X6J A;  1FH0 A;  2WBF X;  4YV8 A;  1ZCM A;  1KHP A;  4PI3 A;  2HHN A;  5CVO B;  1KHQ A;  2VHF A;  3N4C A;  1THE A;  3O0U A;  2AU1 A;  4I07 A;  2F1G A;  4FK5 A;  2R9O A;  4N4Z A;  1GLO A;  2FTD A;  3C9E A;  3OF8 A;  4QRX A;  2DC9 A;  2YJ9 A;  2FYE A;  2NQD B;  4QRV A;  3OIS A;  3HHI A;  1MS6 A;  1AIM A;  1AU0 A;  2PRE A;  3D6S A;  3P5X A;  4BSQ A;  1QMY A;  4AXL A;  2R9C A;  3LTW A;  1NQC A;  3H8C A;  4W5C A;  3BOW A;  3PW3 A;  1ICF A;  2FT2 A;  1PIP A;  1PAD A;  1TL9 A;  5K16 A;  4FIP A;  2R9M A;  3P5V A;  1KFU L;  1GCB A;  3IMA A;  3D9W A;  2CIO A;  1KFX L;  1PPO A;  9PAP A;  1CVZ A;  5JA7 A;  2FO5 A;  4MZO A;  2YJ8 A;  3V6C A;  2XU1 A;  3LXS A;  1BQI A;  2DZY A;  3QSD A;  3PBH A;  1JQP A;  3IUT A;  2OZ2 A;  4BQV A;  4XR7 A;  1EWL A;  2VHS A;  3F75 A;  4YYQ A;  4CDE B;  1BP4 A;  4QRG A;  1PPD A;  2FRQ A;  2G8E A;  3LFY A;  4YYR A;  2YJ2 A;  3RVW A;  2P7U A;  1SP4 B;  2DCA A;  4C5P A;  3OF9 A;  1PE6 A;  4P6G A;  4XUI A;  2BDL A;  3BCN A;  7PCK A;  1ITO A;  3MTN A;  2E02 A;  3P5W A;  4X6H A;  1EWO A;  4NV8 A;  4CZW A;  1U9Q X;  3HWN A;  2OP3 A;  1AU3 A;  2BSZ A;  2HH5 A;  2Y5B A;  4I05 A;  1QOL A;  1XKG A;  4YVA A;  1QXP A;  4MZS A;  3IOQ A;  3CH2 X;  3H8B A;  3BC3 A;  5CHT A;  4DMY A;  3AI8 A;  4YYW A;  1PBH A;  2HXZ A;  2C0Y A;  2AYN A;  4YYS A;  1KXR A;  1GMY A;  3RVX A;  1YVB A;  1YK7 A;  4YYV A;  1MEM A;  4G54 A;  1STF E;  1YT7 A;  1NB5 A;  1W5R A;  3V6E A;  2VFC A;  1VSN A;  3O1G A;  4N8W A;  3N3K A;  4N79 A;  3MOR A;  2AIM A;  2PBH A;  4X6I A;  1ME4 A;  2DCD A;  4B55 A;  4PP2 E;  3S3R A;  3H6S A;  2F7D A;  2CB5 A;  1GEC E;  2JQF R;  2YJC A;  1VJV A;  4I04 A;  2FRA A;  1EWP A;  2PAD A;  3N3G A;  1GX3 A;  4WA6 A;  3USV A;  1K3B B;  4YYU A;  1CSB B;  4QBB A;  3IEJ A;  2AVW A;  4BS6 A;  5CHV A;  1Y4H A;  1O0E A;  1W6F A;  3GCB A;  3IV2 A;  3CBK A;  3H7D A;  2NQA A;  2P0R A;  4P6E A;  2VFB A;  1X9Y A;  5PAD A;  1AEC A;  1F2A A;  1CV8 A;  3KSE A;  4CDC B;  2DCB A;  3IHP A;  1Y08 A;  4AXM A;  1ZIV A;  2B1M A;  1CJL A;  4BS5 A;  2OUL A;  1TU6 A;  2DJG B;  1PPP A;  2XU5 A;  3M99 A;  4HWY A;  5EF4 A;  1YK8 A;  2G7Y A;  5JH3 A;  2R6N A;  1PXV A;  3HHA A;  2ATO A;  1CS8 A;  2DC7 A;  1U9X A;  2FUD A;  1ATK A;  3DF0 A;  1POP A;  3BWK A;  3F5V A;  5FPW A;  1EWM A;  2IPP B;  1Q6K A;  3ZUA A;  3CH3 X;  3MHS A;  1F29 A;  2DZZ A;  3WXG A;  4Q8H A;  3ERV A;  1CQD A;  2AS8 A;  4Q8G A;  1QDQ A;  2G6D A;  3B79 A;  3HD3 A;  4W5B A;  1NB3 A;  5A24 A;  1AYV A;  3I3T A;  4W4U A;  1A6R A;  3WXE A;  2DC8 A;  2B1N A;  3NHE A;  1MIR A;  2R9F A;  1EF7 A;  3TNX A;  1W4T A;  4FJC A;  5EGW A;  2FQ9 A;  4ZUX U;  4PAD A;  1AYU A;  4MSX A;  6PAD A;  8PCH A;  3KWB X;  2E01 A;  3BPM A;  4OEM A;  4KLB A;  5F02 A;  1DF0 A;  1F2C A;  1YAL A;  3KFQ A;  3PNR A;  5CVM A;  4PP1 A;  1NLJ A;  3WXF A;  2AUZ A;  1E2T A;  2DJF B;  3H89 A;  3OVX A;  2G8J A;  1AU2 A;  1S4V A;  1HUC B;  2NQG A;  5CVN B;  1SNK A;  1NL6 A;  4CDD B;  1PCI A;  3OVZ A;  1U9W A;  4RY2 A;  3P5U A;  3MHH A;  1MHW A;  2PNS A;  2HD5 A;  2BDZ A;  3KX1 A;  4OEL A;  3CBJ A;  1M6D A;  4DMX A;  4CDF B;  2E03 A;  3I06 A;  1AU4 A;  2Y6E A;  2ACT A;  5J94 A;  2DCC A;  2GHU A;  3S3Q A;  4GUZ A;  1ME3 A;  2E00 A;  3RVV A;  1DEU A;  2H7J A;  2YJB A;  3KW9 A;  2AYO A;  2DC6 A;  2IBI A;  1BY8 A;  1BGO A;  1MDW A;  3PDF A;  2GFO A;  2NQI A;  1MEG A;  1CTE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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