3KSEA

Unreduced cathepsin l in complex with stefin a
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDDNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unreduced cathepsin L in complex with stefin A
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Homo sapiens
molecule keywords Cathepsin L1
total genus 67
structure length 219
sequence length 220
chains with identical sequence B, C
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2009-11-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3kseA00
3F5VA 3CBKA 1CS8A 1GLOA 4PP2E 1KHPA 3RVWA 3RVVA 2DJGB 1PPDA 1NLJA 2AYOA 3IHPA 3ZUAA 3MHSA 1HUCB 1ZCMA 1U9VA 3WXFA 4RY2A 2G6DA 1ME4A 4HWYA 1GMYA 3OISA 1BQIA 3DF0A 3P5VA 4N4ZA 2NQAA 2AU1A 3BOWA 4CDCB 5J94A 1STFE 5CHVA 4PADA 2HXZA 4XR7A 5K16A 4YYUA 3B79A 1EF7A 2R9NA 3MTNA 3QSDA 1CQDA 3BPFA 1PADA 1CVZA 1PPPA 4BS6A 4XUIA 2G8EA 2E01A 2DC6A 2R6NA 3BC3A 1YK8A 2DC9A 1X9YA 2AUZA 1PE6A 1U9QX 1GCBA 3P5UA 2P0RA 2GFOA 1SNKA 1Y4HA 3CBJA 2AVWA 9PAPA 2P86A 4G54A 1KXRA 2BDZA 1F2CA 1BP4A 3KKUA 1YK7A 1NL6A 2YJ9A 4FJCA 3I06A 1BY8A 1CTEA 1PIPA 4QRVA 2FYEA 3QT4A 4QH6A 1YVBA 4I07A 3K24A 3K9MA 3ERVA 1NQCA 1TU6A 5CVOB 3D6SA 2PREA 4DMYA 3USVA 3PDFA 4K7CA 5EGWA 1Q6KA 2FO5A 4OELA 1QMYA 2DCAA 3PBHA 1DF0A 1F2AA 1K3BB 2R9CA 1CJLA 3OVXA 4QBBA 1F29A 2HH5A 2DC7A 1AU0A 4CDEB 3K8UA 4DMXA 2XU5A 3PW3A 4YVAA 4ZUXU 4FK5A 1ITOA 3H6SA 2DZZA 1CV8A 1NB3A 3CH3X 3O1GA 1QOLA 2C0YA 2IBIA 2CIOA 1ATKA 4YYRA 1AYVA 1EWLA 1ICFA 3H8CA 2OZ2A 3H7DA 4CDDB 3CH2X 4WA6A 3N4CA 1DEUA 1GECE 4KLBA 2F7DA 2AS8A 3AI8A 1S4VA 1AYWA 1BGOA 3IMAA 2NQGA 3HHIA 1MDWA 1CB5A 2NQDB 3E1ZB 4QRGA 1POPA 4W5BA 2E02A 4X6HA 3H8BA 3KSEA 2VHSA 3V6CA 1QDQA 1CSBB 1U9WA 1NB5A 4PP1A 4PI3A 1FH0A 1CPJA 1MIRA 5CHTA 4BPVA 1PCIA 1MEMA 2NQIA 3BPMA 2PBHA 1EWOA 4YYVA 1NPZA 4OEMA 2Y5BA 2H7JA 3M99A 2YJCA 2HHNA 4P6GA 3HD3A 1ME3A 4YYSA 2IPPB 4CZWA 2R9OA 1M6DA 2XU4A 1PXVA 4YV8A 2YJBA 1AECA 1SP4B 2WBFX 1F2BA 3KX1A 5JH3A 1U5IA 2ATOA 2AIMA 5F02A 2O6XA 1PBHA 1VJVA 3IOQA 3V6EA 1AU4A 1AU3A 2G8JA 2XU3A 4AXLA 3KFQA 2AYNA 5JA7A 2E03A 2ACTA 3HWNA 4AXMA 1PPOA 4MSXA 2DZYA 3I3TA 2R9FA 3WXEA 4BSQA 1THEA 2B1MA 1AYUA 1TLOA 2FQ9A 3WXGA 2JQFR 2B1NA 1Y08A 5PADA 3S3QA 4I05A 5A24A 1KFUL 3P5WA 2F1GA 1AIMA 3OVZA 3KWBX 4I04A 4MZOA 2CB5A 3P5XA 1U9XA 2DJFB 4FIPA 2FUDA 2E00A 3IUTA 2YJ2A 3MHHA 3MORA 3LFYA 3N3KA 4W5CA 2R9MA 4YYQA 1ZIVA 1O0EA 4Q8HA 1QXPA 3GCBA 3IV2A 3H89A 4BS5A 4N8WA 4QRXA 2XU1A 5CVMA 1JQPA 3KW9A 3OF8A 1XKGA 4X6IA 4MZSA 3TNXA 3BCNA 2FRQA 4BQVA 2FRAA 1IWDA 2P7UA 5FPWA 2GHUA 3C9EA 3S3RA 3U8EA 2OULA 2DCCA 2PADA 1A6RA 1MHWA 3LXSA 3N3GA 3OF9A 7PCKA 3HHAA 4P6EA 2AUXA 4CDFB 3NHEA 1PPNA 2OP3A 2Y6EA 2FT2A 3O0UA 2PNSA 4X6JA 3KWZA 4Q8GA 1KFXL 2ARYA 1EWPA 1AU2A 2JQGR 1MS6A 8PCHA 5CVNB 1KHQA 1TL9A 3IEJA 2DCDA 2G7YA 1EWMA 1MEGA 3F75A 2DCBA 2HD5A 3QJ3A 2VHFA 3PNRA 2DC8A 4W4UA 3BWKA 2YJ8A 3RVXA 6PADA 2BDLA 5EF4A 1VSNA 1YALA 2FTDA 1YT7A 4N79A 4YYWA
chains in the Genus database with same CATH superfamily
3F5VA 3CBKA 1CS8A 1DKIA 1GLOA 4IUMA 1KHPA 4PP2E 3RVWA 4XZXA 3RVVA 2DJGB 1PPDA 1NLJA 2AYOA 3IHPA 3ZUAA 3MHSA 1HUCB 1ZCMA 1U9VA 4BOSA 3WXFA 4RY2A 2Z84A 2G6DA 1ME4A 3PT2A 3C0RA 4HWYA 1GMYA 3OISA 1BQIA 3DF0A 3P5VA 4N4ZA 2NQAA 2AU1A 3BOWA 4CDCB 5J94A 1STFE 1UKFA 5CHVA 2BU3A 3PHUA 4PADA 2HXZA 4XR7A 5K16A 4YYUA 3B79A 1EF7A 2R9NA 3MTNA 3QSDA 1CQDA 3BPFA 4D8IA 1PADA 1CVZA 1PPPA 4BS6A 3ZNHA 4XUIA 3MP2A 3W31A 2G8EA 2E01A 2DC6A 2R6NA 3BC3A 1YK8A 2DC9A 1X9YA 2AUZA 1PE6A 1U9QX 1GCBA 4OVZA 3P5UA 2P0RA 2GFOA 1SNKA 2JRIA 1Y4HA 3CBJA 2AVWA 4BOPA 9PAPA 2P86A 4G54A 1KXRA 2BDZA 1F2CA 1BP4A 3KKUA 4R3DA 1YK7A 1NL6A 2YJ9A 4FJCA 3I06A 1BY8A 1CTEA 1PIPA 4QRVA 2FYEA 3QT4A 1YVBA 4QH6A 4I07A 3K24A 3K9MA 3PRPA 4M0WA 3TMPA 3ERVA 1NQCA 1TU6A 4A5UA 3PSEA 5CVOB 3D6SA 2PREA 4DMYA 3USVA 3PDFA 4K7CA 5EGWA 1Q6KA 2FO5A 4OELA 2UZJA 1QMYA 2DCAA 3PBHA 1DF0A 1F2AA 1K3BB 2R9CA 1CJLA 3OVXA 4QBBA 1F29A 2HH5A 2DC7A 1AU0A 5JZEA 4CDEB 3K8UA 4DMXA 2XU5A 3PW3A 4YVAA 4ZUXU 3BY4A 4FK5A 4IP3A 1ITOA 1PVJA 3H6SA 2DZZA 1CV8A 1NB3A 4D8BA 3CH3X 3O1GA 1QOLA 2C0YA 2FE8A 2IBIA 2CIOA 4WURA 1ATKA 4YYRA 1AYVA 1EWLA 1ICFA 3H8CA 2OZ2A 3H7DA 4RF1A 4CDDB 3CH2X 4WA6A 3N4CA 3O65A 1DEUA 1GECE 4KLBA 2F7DA 4RNAA 2AS8A 3AI8A 1S4VA 1AYWA 1BGOA 3IMAA 2NQGA 3RNVA 3HHIA 4PT5A 1MDWA 1CB5A 2NQDB 3E1ZB 4QRGA 1POPA 4W5BA 3OQCA 2E02A 4REZA 4X6HA 2HWKA 3H8BA 3KSEA 2VHSA 3V6CA 1QDQA 1CSBB 1U9WA 5E6JA 1NB5A 4PP1A 4PI3A 1FH0A 1CPJA 1MIRA 5CHTA 4BPVA 1PCIA 1MEMA 2NQIA 3BPMA 2PBHA 1EWOA 4YYVA 1NPZA 4OEMA 3TRKA 2Y5BA 3IFUA 2H7JA 3M99A 2YJCA 2HHNA 4P6GA 3HD3A 4MM3B 1YZBA 1ME3A 4P16A 4YYSA 2IPPB 4CZWA 2R9OA 1M6DA 2XU4A 3PRMA 1PXVA 4YV8A 2YJBA 1AECA 1SP4B 2WBFX 1F2BA 3KX1A 5JH3A 2AGAA 1U5IA 2ATOA 2AIMA 3MJ5A 5F02A 2O6XA 1PBHA 1VJVA 3IOQA 3V6EA 1AU4A 1AU3A 2G8JA 2XU3A 4AXLA 3KFQA 2AYNA 5JA7A 2E03A 2ACTA 3HWNA 4AXMA 1PPOA 4MSXA 2DZYA 3I3TA 2R9FA 3WXEA 4BSQA 1THEA 2B1MA 4HXDB 1AYUA 1TLOA 3PHWA 2FQ9A 3WXGA 2JQFR 2B1NA 1Y08A 3BB7A 5PADA 3S3QA 4I05A 5A24A 3B21A 1KFUL 3BBAA 3P5WA 2F1GA 1AIMA 3OVZA 3KWBX 4I04A 5EZQA 4D8EA 4MZOA 2CB5A 2JTCA 4GUAA 3P5XA 1U9XA 2DJFB 4FIPA 2FUDA 4MI7A 2E00A 3IUTA 2YJ2A 3MHHA 3MORA 3LFYA 3N3KA 4W5CA 2R9MA 4YYQA 1ZIVA 1O0EA 4Q8HA 1QXPA 3GCBA 3IV2A 3H89A 4BS5A 4N8WA 4QRXA 2XU1A 5CVMA 1JQPA 3KW9A 5EZSA 3OF8A 3MTVA 4OVZB 4RKXA 1XKGA 4X6IA 4MZSA 3TNXA 3BCNA 5KO3A 3E9SA 2FRQA 4BQVA 2FRAA 1IWDA 2P7UA 5FPWA 2J7QA 2GHUA 3C9EA 3S3RA 3U8EA 3PHXA 2OULA 4OW0A 2DCCA 2PADA 1A6RA 1MHWA 3LXSA 3N3GA 3OF9A 4BOZA 3HHAA 7PCKA 4P6EA 2AUXA 4CDFB 3NHEA 1PPNA 2OP3A 2Y6EA 4BOUA 2FT2A 3O0UA 2PNSA 4X6JA 3W30A 3KWZA 2BTWB 4Q8GA 1KFXL 2ARYA 1EWPA 1AU2A 2JQGR 1MS6A 8PCHA 5CVNB 1KHQA 1TL9A 4ZTBA 3IEJA 2DCDA 2G7YA 1EWMA 1MEGA 3F75A 2J7QC 2DCBA 2HD5A 3QJ3A 2VHFA 3PNRA 2DC8A 2BTWA 4W4UA 3BWKA 2YJ8A 3RVXA 6PADA 2DOSA 4RF0A 2BDLA 4BOQA 5EF4A 1VSNA 1YALA 2FTDA 1YT7A 4N79A 4YYWA
chains in the Genus database with same CATH topology
3F5VA 3CBKA 1CS8A 1GLOA 4PP2E 1KHPA 3RVWA 3RVVA 2DJGB 1PPDA 1NLJA 2AYOA 3IHPA 3ZUAA 3MHSA 1HUCB 1ZCMA 1W6FA 1U9VA 3WXFA 3LTWA 4RY2A 2G6DA 1ME4A 4HWYA 1GMYA 3OISA 1BQIA 3DF0A 3P5VA 4N4ZA 2NQAA 2VFBA 2AU1A 3BOWA 4CDCB 2BSZA 4BGFA 5J94A 1STFE 5CHVA 4PADA 2HXZA 4XR7A 5K16A 4YYUA 3B79A 1EF7A 2R9NA 3MTNA 3QSDA 1CQDA 3BPFA 1PADA 1CVZA 1PPPA 4BS6A 4XUIA 2G8EA 2E01A 2DC6A 2R6NA 3BC3A 1YK8A 2DC9A 1X9YA 2AUZA 1PE6A 1U9QX 1GCBA 3P5UA 2P0RA 2GFOA 1SNKA 1Y4HA 3CBJA 2AVWA 9PAPA 2P86A 4G54A 1KXRA 2BDZA 1F2CA 1BP4A 3KKUA 1YK7A 1NL6A 2YJ9A 4FJCA 3I06A 1BY8A 1CTEA 1PIPA 4QRVA 2FYEA 3QT4A 1YVBA 4QH6A 4I07A 3K24A 3K9MA 4GUZA 3ERVA 1NQCA 1TU6A 1E2TA 5CVOB 3D6SA 2PREA 4DMYA 3USVA 3PDFA 4K7CA 5EGWA 1Q6KA 2FO5A 4OELA 1QMYA 2DCAA 3PBHA 1DF0A 1F2AA 1K3BB 2R9CA 1CJLA 3OVXA 4QBBA 1F29A 1W4TA 2HH5A 2DC7A 1AU0A 4CDEB 3K8UA 4DMXA 2XU5A 3PW3A 4YVAA 4ZUXU 4FK5A 1ITOA 3H6SA 2DZZA 1CV8A 1NB3A 3CH3X 3O1GA 1QOLA 2C0YA 2IBIA 2CIOA 1ATKA 4YYRA 1AYVA 1EWLA 1ICFA 3H8CA 2OZ2A 3H7DA 4CDDB 3CH2X 4WA6A 3N4CA 1DEUA 1GECE 4KLBA 2F7DA 2AS8A 3AI8A 1S4VA 1AYWA 1BGOA 3IMAA 2NQGA 3HHIA 1MDWA 1CB5A 2NQDB 1GX3A 3E1ZB 4QRGA 1POPA 4W5BA 2E02A 4X6HA 3H8BA 3KSEA 2VHSA 3V6CA 1QDQA 1CSBB 1U9WA 1NB5A 4PP1A 4PI3A 1FH0A 1CPJA 1MIRA 5CHTA 4BPVA 1PCIA 1MEMA 2NQIA 3BPMA 2PBHA 1EWOA 4YYVA 1NPZA 4OEMA 2Y5BA 2H7JA 3M99A 2YJCA 2HHNA 4P6GA 3HD3A 1ME3A 4YYSA 2IPPB 4CZWA 2R9OA 1M6DA 2XU4A 1PXVA 4YV8A 2YJBA 1AECA 1SP4B 2WBFX 1F2BA 3KX1A 5JH3A 1U5IA 2ATOA 2AIMA 5F02A 2O6XA 1PBHA 1VJVA 3IOQA 3V6EA 1AU4A 1AU3A 2G8JA 2XU3A 4AXLA 3KFQA 2AYNA 5JA7A 2E03A 2ACTA 3HWNA 4AXMA 1PPOA 4MSXA 2DZYA 3I3TA 2R9FA 3WXEA 4BSQA 1THEA 2B1MA 1AYUA 1TLOA 2FQ9A 3WXGA 2JQFR 2B1NA 1Y08A 5PADA 3S3QA 4I05A 5A24A 1KFUL 3P5WA 3D9WA 2F1GA 1AIMA 3OVZA 3KWBX 4I04A 4MZOA 2CB5A 3P5XA 1U9XA 2DJFB 4FIPA 2FUDA 2E00A 3IUTA 2YJ2A 3MHHA 3MORA 3LFYA 3N3KA 4W5CA 2R9MA 4YYQA 1ZIVA 1O0EA 4Q8HA 1QXPA 3GCBA 3IV2A 3H89A 4BS5A 4N8WA 4QRXA 2XU1A 5CVMA 1JQPA 3KW9A 3OF8A 1XKGA 4X6IA 4MZSA 3TNXA 3BCNA 2FRQA 4BQVA 2FRAA 2VFCA 1IWDA 4NV8A 2P7UA 5FPWA 2GHUA 3C9EA 3S3RA 4C5PA 3U8EA 4NV7A 2OULA 2DCCA 2PADA 1A6RA 1MHWA 3LXSA 3N3GA 3OF9A 7PCKA 3HHAA 4P6EA 2AUXA 4CDFB 3NHEA 1PPNA 2OP3A 2Y6EA 2FT2A 3O0UA 2PNSA 4X6JA 3KWZA 4Q8GA 1KFXL 2ARYA 1EWPA 1W5RA 1AU2A 2JQGR 1MS6A 8PCHA 5CVNB 1KHQA 1TL9A 3IEJA 2DCDA 2G7YA 1EWMA 1MEGA 3F75A 2DCBA 2HD5A 3QJ3A 2VHFA 3PNRA 2DC8A 4W4UA 3BWKA 2YJ8A 3RVXA 6PADA 2BDLA 5EF4A 1VSNA 1YALA 4B55A 2FTDA 1YT7A 4N79A 4YYWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3F5V A;  3CBK A;  1CS8 A;  1GLO A;  4PP2 E;  1KHP A;  3RVW A;  3RVV A;  2DJG B;  1PPD A;  1NLJ A;  2AYO A;  3IHP A;  3ZUA A;  3MHS A;  1HUC B;  1ZCM A;  1U9V A;  3WXF A;  4RY2 A;  2G6D A;  1ME4 A;  4HWY A;  1GMY A;  3OIS A;  1BQI A;  3DF0 A;  3P5V A;  4N4Z A;  2NQA A;  2AU1 A;  3BOW A;  4CDC B;  5J94 A;  1STF E;  5CHV A;  4PAD A;  2HXZ A;  4XR7 A;  5K16 A;  4YYU A;  3B79 A;  1EF7 A;  2R9N A;  3MTN A;  3QSD A;  1CQD A;  3BPF A;  1PAD A;  1CVZ A;  1PPP A;  4BS6 A;  4XUI A;  2G8E A;  2E01 A;  2DC6 A;  2R6N A;  3BC3 A;  1YK8 A;  2DC9 A;  1X9Y A;  2AUZ A;  1PE6 A;  1U9Q X;  1GCB A;  3P5U A;  2P0R A;  2GFO A;  1SNK A;  1Y4H A;  3CBJ A;  2AVW A;  9PAP A;  2P86 A;  4G54 A;  1KXR A;  2BDZ A;  1F2C A;  1BP4 A;  3KKU A;  1YK7 A;  1NL6 A;  2YJ9 A;  4FJC A;  3I06 A;  1BY8 A;  1CTE A;  1PIP A;  4QRV A;  2FYE A;  3QT4 A;  4QH6 A;  1YVB A;  4I07 A;  3K24 A;  3K9M A;  3ERV A;  1NQC A;  1TU6 A;  5CVO B;  3D6S A;  2PRE A;  4DMY A;  3USV A;  3PDF A;  4K7C A;  5EGW A;  1Q6K A;  2FO5 A;  4OEL A;  1QMY A;  2DCA A;  3PBH A;  1DF0 A;  1F2A A;  1K3B B;  2R9C A;  1CJL A;  3OVX A;  4QBB A;  1F29 A;  2HH5 A;  2DC7 A;  1AU0 A;  4CDE B;  3K8U A;  4DMX A;  2XU5 A;  3PW3 A;  4YVA A;  4ZUX U;  4FK5 A;  1ITO A;  3H6S A;  2DZZ A;  1CV8 A;  1NB3 A;  3CH3 X;  3O1G A;  1QOL A;  2C0Y A;  2IBI A;  2CIO A;  1ATK A;  4YYR A;  1AYV A;  1EWL A;  1ICF A;  3H8C A;  2OZ2 A;  3H7D A;  4CDD B;  3CH2 X;  4WA6 A;  3N4C A;  1DEU A;  1GEC E;  4KLB A;  2F7D A;  2AS8 A;  3AI8 A;  1S4V A;  1AYW A;  1BGO A;  3IMA A;  2NQG A;  3HHI A;  1MDW A;  1CB5 A;  2NQD B;  3E1Z B;  4QRG A;  1POP A;  4W5B A;  2E02 A;  4X6H A;  3H8B A;  3KSE A;  2VHS A;  3V6C A;  1QDQ A;  1CSB B;  1U9W A;  1NB5 A;  4PP1 A;  4PI3 A;  1FH0 A;  1CPJ A;  1MIR A;  5CHT A;  4BPV A;  1PCI A;  1MEM A;  2NQI A;  3BPM A;  2PBH A;  1EWO A;  4YYV A;  1NPZ A;  4OEM A;  2Y5B A;  2H7J A;  3M99 A;  2YJC A;  2HHN A;  4P6G A;  3HD3 A;  1ME3 A;  4YYS A;  2IPP B;  4CZW A;  2R9O A;  1M6D A;  2XU4 A;  1PXV A;  4YV8 A;  2YJB A;  1AEC A;  1SP4 B;  2WBF X;  1F2B A;  3KX1 A;  5JH3 A;  1U5I A;  2ATO A;  2AIM A;  5F02 A;  2O6X A;  1PBH A;  1VJV A;  3IOQ A;  3V6E A;  1AU4 A;  1AU3 A;  2G8J A;  2XU3 A;  4AXL A;  3KFQ A;  2AYN A;  5JA7 A;  2E03 A;  2ACT A;  3HWN A;  4AXM A;  1PPO A;  4MSX A;  2DZY A;  3I3T A;  2R9F A;  3WXE A;  4BSQ A;  1THE A;  2B1M A;  1AYU A;  1TLO A;  2FQ9 A;  3WXG A;  2JQF R;  2B1N A;  1Y08 A;  5PAD A;  3S3Q A;  4I05 A;  5A24 A;  1KFU L;  3P5W A;  2F1G A;  1AIM A;  3OVZ A;  3KWB X;  4I04 A;  4MZO A;  2CB5 A;  3P5X A;  1U9X A;  2DJF B;  4FIP A;  2FUD A;  2E00 A;  3IUT A;  2YJ2 A;  3MHH A;  3MOR A;  3LFY A;  3N3K A;  4W5C A;  2R9M A;  4YYQ A;  1ZIV A;  1O0E A;  4Q8H A;  1QXP A;  3GCB A;  3IV2 A;  3H89 A;  4BS5 A;  4N8W A;  4QRX A;  2XU1 A;  5CVM A;  1JQP A;  3KW9 A;  3OF8 A;  1XKG A;  4X6I A;  4MZS A;  3TNX A;  3BCN A;  2FRQ A;  4BQV A;  2FRA A;  1IWD A;  2P7U A;  5FPW A;  2GHU A;  3C9E A;  3S3R A;  3U8E A;  2OUL A;  2DCC A;  2PAD A;  1A6R A;  1MHW A;  3LXS A;  3N3G A;  3OF9 A;  7PCK A;  3HHA A;  4P6E A;  2AUX A;  4CDF B;  3NHE A;  1PPN A;  2OP3 A;  2Y6E A;  2FT2 A;  3O0U A;  2PNS A;  4X6J A;  3KWZ A;  4Q8G A;  1KFX L;  2ARY A;  1EWP A;  1AU2 A;  2JQG R;  1MS6 A;  8PCH A;  5CVN B;  1KHQ A;  1TL9 A;  3IEJ A;  2DCD A;  2G7Y A;  1EWM A;  1MEG A;  3F75 A;  2DCB A;  2HD5 A;  3QJ3 A;  2VHF A;  3PNR A;  2DC8 A;  4W4U A;  3BWK A;  2YJ8 A;  3RVX A;  6PAD A;  2BDL A;  5EF4 A;  1VSN A;  1YAL A;  2FTD A;  1YT7 A;  4N79 A;  4YYW A; 
#chains in the Genus database with same CATH topology
 3F5V A;  3CBK A;  1CS8 A;  1DKI A;  1GLO A;  4IUM A;  1KHP A;  4PP2 E;  3RVW A;  4XZX A;  3RVV A;  2DJG B;  1PPD A;  1NLJ A;  2AYO A;  3IHP A;  3ZUA A;  3MHS A;  1HUC B;  1ZCM A;  1U9V A;  4BOS A;  3WXF A;  4RY2 A;  2Z84 A;  2G6D A;  1ME4 A;  3PT2 A;  3C0R A;  4HWY A;  1GMY A;  3OIS A;  1BQI A;  3DF0 A;  3P5V A;  4N4Z A;  2NQA A;  2AU1 A;  3BOW A;  4CDC B;  5J94 A;  1STF E;  1UKF A;  5CHV A;  2BU3 A;  3PHU A;  4PAD A;  2HXZ A;  4XR7 A;  5K16 A;  4YYU A;  3B79 A;  1EF7 A;  2R9N A;  3MTN A;  3QSD A;  1CQD A;  3BPF A;  4D8I A;  1PAD A;  1CVZ A;  1PPP A;  4BS6 A;  3ZNH A;  4XUI A;  3MP2 A;  3W31 A;  2G8E A;  2E01 A;  2DC6 A;  2R6N A;  3BC3 A;  1YK8 A;  2DC9 A;  1X9Y A;  2AUZ A;  1PE6 A;  1U9Q X;  1GCB A;  4OVZ A;  3P5U A;  2P0R A;  2GFO A;  1SNK A;  2JRI A;  1Y4H A;  3CBJ A;  2AVW A;  4BOP A;  9PAP A;  2P86 A;  4G54 A;  1KXR A;  2BDZ A;  1F2C A;  1BP4 A;  3KKU A;  4R3D A;  1YK7 A;  1NL6 A;  2YJ9 A;  4FJC A;  3I06 A;  1BY8 A;  1CTE A;  1PIP A;  4QRV A;  2FYE A;  3QT4 A;  1YVB A;  4QH6 A;  4I07 A;  3K24 A;  3K9M A;  3PRP A;  4M0W A;  3TMP A;  3ERV A;  1NQC A;  1TU6 A;  4A5U A;  3PSE A;  5CVO B;  3D6S A;  2PRE A;  4DMY A;  3USV A;  3PDF A;  4K7C A;  5EGW A;  1Q6K A;  2FO5 A;  4OEL A;  2UZJ A;  1QMY A;  2DCA A;  3PBH A;  1DF0 A;  1F2A A;  1K3B B;  2R9C A;  1CJL A;  3OVX A;  4QBB A;  1F29 A;  2HH5 A;  2DC7 A;  1AU0 A;  5JZE A;  4CDE B;  3K8U A;  4DMX A;  2XU5 A;  3PW3 A;  4YVA A;  4ZUX U;  3BY4 A;  4FK5 A;  4IP3 A;  1ITO A;  1PVJ A;  3H6S A;  2DZZ A;  1CV8 A;  1NB3 A;  4D8B A;  3CH3 X;  3O1G A;  1QOL A;  2C0Y A;  2FE8 A;  2IBI A;  2CIO A;  4WUR A;  1ATK A;  4YYR A;  1AYV A;  1EWL A;  1ICF A;  3H8C A;  2OZ2 A;  3H7D A;  4RF1 A;  4CDD B;  3CH2 X;  4WA6 A;  3N4C A;  3O65 A;  1DEU A;  1GEC E;  4KLB A;  2F7D A;  4RNA A;  2AS8 A;  3AI8 A;  1S4V A;  1AYW A;  1BGO A;  3IMA A;  2NQG A;  3RNV A;  3HHI A;  4PT5 A;  1MDW A;  1CB5 A;  2NQD B;  3E1Z B;  4QRG A;  1POP A;  4W5B A;  3OQC A;  2E02 A;  4REZ A;  4X6H A;  2HWK A;  3H8B A;  3KSE A;  2VHS A;  3V6C A;  1QDQ A;  1CSB B;  1U9W A;  5E6J A;  1NB5 A;  4PP1 A;  4PI3 A;  1FH0 A;  1CPJ A;  1MIR A;  5CHT A;  4BPV A;  1PCI A;  1MEM A;  2NQI A;  3BPM A;  2PBH A;  1EWO A;  4YYV A;  1NPZ A;  4OEM A;  3TRK A;  2Y5B A;  3IFU A;  2H7J A;  3M99 A;  2YJC A;  2HHN A;  4P6G A;  3HD3 A;  4MM3 B;  1YZB A;  1ME3 A;  4P16 A;  4YYS A;  2IPP B;  4CZW A;  2R9O A;  1M6D A;  2XU4 A;  3PRM A;  1PXV A;  4YV8 A;  2YJB A;  1AEC A;  1SP4 B;  2WBF X;  1F2B A;  3KX1 A;  5JH3 A;  2AGA A;  1U5I A;  2ATO A;  2AIM A;  3MJ5 A;  5F02 A;  2O6X A;  1PBH A;  1VJV A;  3IOQ A;  3V6E A;  1AU4 A;  1AU3 A;  2G8J A;  2XU3 A;  4AXL A;  3KFQ A;  2AYN A;  5JA7 A;  2E03 A;  2ACT A;  3HWN A;  4AXM A;  1PPO A;  4MSX A;  2DZY A;  3I3T A;  2R9F A;  3WXE A;  4BSQ A;  1THE A;  2B1M A;  4HXD B;  1AYU A;  1TLO A;  3PHW A;  2FQ9 A;  3WXG A;  2JQF R;  2B1N A;  1Y08 A;  3BB7 A;  5PAD A;  3S3Q A;  4I05 A;  5A24 A;  3B21 A;  1KFU L;  3BBA A;  3P5W A;  2F1G A;  1AIM A;  3OVZ A;  3KWB X;  4I04 A;  5EZQ A;  4D8E A;  4MZO A;  2CB5 A;  2JTC A;  4GUA A;  3P5X A;  1U9X A;  2DJF B;  4FIP A;  2FUD A;  4MI7 A;  2E00 A;  3IUT A;  2YJ2 A;  3MHH A;  3MOR A;  3LFY A;  3N3K A;  4W5C A;  2R9M A;  4YYQ A;  1ZIV A;  1O0E A;  4Q8H A;  1QXP A;  3GCB A;  3IV2 A;  3H89 A;  4BS5 A;  4N8W A;  4QRX A;  2XU1 A;  5CVM A;  1JQP A;  3KW9 A;  5EZS A;  3OF8 A;  3MTV A;  4OVZ B;  4RKX A;  1XKG A;  4X6I A;  4MZS A;  3TNX A;  3BCN A;  5KO3 A;  3E9S A;  2FRQ A;  4BQV A;  2FRA A;  1IWD A;  2P7U A;  5FPW A;  2J7Q A;  2GHU A;  3C9E A;  3S3R A;  3U8E A;  3PHX A;  2OUL A;  4OW0 A;  2DCC A;  2PAD A;  1A6R A;  1MHW A;  3LXS A;  3N3G A;  3OF9 A;  4BOZ A;  3HHA A;  7PCK A;  4P6E A;  2AUX A;  4CDF B;  3NHE A;  1PPN A;  2OP3 A;  2Y6E A;  4BOU A;  2FT2 A;  3O0U A;  2PNS A;  4X6J A;  3W30 A;  3KWZ A;  2BTW B;  4Q8G A;  1KFX L;  2ARY A;  1EWP A;  1AU2 A;  2JQG R;  1MS6 A;  8PCH A;  5CVN B;  1KHQ A;  1TL9 A;  4ZTB A;  3IEJ A;  2DCD A;  2G7Y A;  1EWM A;  1MEG A;  3F75 A;  2J7Q C;  2DCB A;  2HD5 A;  3QJ3 A;  2VHF A;  3PNR A;  2DC8 A;  2BTW A;  4W4U A;  3BWK A;  2YJ8 A;  3RVX A;  6PAD A;  2DOS A;  4RF0 A;  2BDL A;  4BOQ A;  5EF4 A;  1VSN A;  1YAL A;  2FTD A;  1YT7 A;  4N79 A;  4YYW A; 
#chains in the Genus database with same CATH homology
 3F5V A;  3CBK A;  1CS8 A;  1GLO A;  4PP2 E;  1KHP A;  3RVW A;  3RVV A;  2DJG B;  1PPD A;  1NLJ A;  2AYO A;  3IHP A;  3ZUA A;  3MHS A;  1HUC B;  1ZCM A;  1W6F A;  1U9V A;  3WXF A;  3LTW A;  4RY2 A;  2G6D A;  1ME4 A;  4HWY A;  1GMY A;  3OIS A;  1BQI A;  3DF0 A;  3P5V A;  4N4Z A;  2NQA A;  2VFB A;  2AU1 A;  3BOW A;  4CDC B;  2BSZ A;  4BGF A;  5J94 A;  1STF E;  5CHV A;  4PAD A;  2HXZ A;  4XR7 A;  5K16 A;  4YYU A;  3B79 A;  1EF7 A;  2R9N A;  3MTN A;  3QSD A;  1CQD A;  3BPF A;  1PAD A;  1CVZ A;  1PPP A;  4BS6 A;  4XUI A;  2G8E A;  2E01 A;  2DC6 A;  2R6N A;  3BC3 A;  1YK8 A;  2DC9 A;  1X9Y A;  2AUZ A;  1PE6 A;  1U9Q X;  1GCB A;  3P5U A;  2P0R A;  2GFO A;  1SNK A;  1Y4H A;  3CBJ A;  2AVW A;  9PAP A;  2P86 A;  4G54 A;  1KXR A;  2BDZ A;  1F2C A;  1BP4 A;  3KKU A;  1YK7 A;  1NL6 A;  2YJ9 A;  4FJC A;  3I06 A;  1BY8 A;  1CTE A;  1PIP A;  4QRV A;  2FYE A;  3QT4 A;  1YVB A;  4QH6 A;  4I07 A;  3K24 A;  3K9M A;  4GUZ A;  3ERV A;  1NQC A;  1TU6 A;  1E2T A;  5CVO B;  3D6S A;  2PRE A;  4DMY A;  3USV A;  3PDF A;  4K7C A;  5EGW A;  1Q6K A;  2FO5 A;  4OEL A;  1QMY A;  2DCA A;  3PBH A;  1DF0 A;  1F2A A;  1K3B B;  2R9C A;  1CJL A;  3OVX A;  4QBB A;  1F29 A;  1W4T A;  2HH5 A;  2DC7 A;  1AU0 A;  4CDE B;  3K8U A;  4DMX A;  2XU5 A;  3PW3 A;  4YVA A;  4ZUX U;  4FK5 A;  1ITO A;  3H6S A;  2DZZ A;  1CV8 A;  1NB3 A;  3CH3 X;  3O1G A;  1QOL A;  2C0Y A;  2IBI A;  2CIO A;  1ATK A;  4YYR A;  1AYV A;  1EWL A;  1ICF A;  3H8C A;  2OZ2 A;  3H7D A;  4CDD B;  3CH2 X;  4WA6 A;  3N4C A;  1DEU A;  1GEC E;  4KLB A;  2F7D A;  2AS8 A;  3AI8 A;  1S4V A;  1AYW A;  1BGO A;  3IMA A;  2NQG A;  3HHI A;  1MDW A;  1CB5 A;  2NQD B;  1GX3 A;  3E1Z B;  4QRG A;  1POP A;  4W5B A;  2E02 A;  4X6H A;  3H8B A;  3KSE A;  2VHS A;  3V6C A;  1QDQ A;  1CSB B;  1U9W A;  1NB5 A;  4PP1 A;  4PI3 A;  1FH0 A;  1CPJ A;  1MIR A;  5CHT A;  4BPV A;  1PCI A;  1MEM A;  2NQI A;  3BPM A;  2PBH A;  1EWO A;  4YYV A;  1NPZ A;  4OEM A;  2Y5B A;  2H7J A;  3M99 A;  2YJC A;  2HHN A;  4P6G A;  3HD3 A;  1ME3 A;  4YYS A;  2IPP B;  4CZW A;  2R9O A;  1M6D A;  2XU4 A;  1PXV A;  4YV8 A;  2YJB A;  1AEC A;  1SP4 B;  2WBF X;  1F2B A;  3KX1 A;  5JH3 A;  1U5I A;  2ATO A;  2AIM A;  5F02 A;  2O6X A;  1PBH A;  1VJV A;  3IOQ A;  3V6E A;  1AU4 A;  1AU3 A;  2G8J A;  2XU3 A;  4AXL A;  3KFQ A;  2AYN A;  5JA7 A;  2E03 A;  2ACT A;  3HWN A;  4AXM A;  1PPO A;  4MSX A;  2DZY A;  3I3T A;  2R9F A;  3WXE A;  4BSQ A;  1THE A;  2B1M A;  1AYU A;  1TLO A;  2FQ9 A;  3WXG A;  2JQF R;  2B1N A;  1Y08 A;  5PAD A;  3S3Q A;  4I05 A;  5A24 A;  1KFU L;  3P5W A;  3D9W A;  2F1G A;  1AIM A;  3OVZ A;  3KWB X;  4I04 A;  4MZO A;  2CB5 A;  3P5X A;  1U9X A;  2DJF B;  4FIP A;  2FUD A;  2E00 A;  3IUT A;  2YJ2 A;  3MHH A;  3MOR A;  3LFY A;  3N3K A;  4W5C A;  2R9M A;  4YYQ A;  1ZIV A;  1O0E A;  4Q8H A;  1QXP A;  3GCB A;  3IV2 A;  3H89 A;  4BS5 A;  4N8W A;  4QRX A;  2XU1 A;  5CVM A;  1JQP A;  3KW9 A;  3OF8 A;  1XKG A;  4X6I A;  4MZS A;  3TNX A;  3BCN A;  2FRQ A;  4BQV A;  2FRA A;  2VFC A;  1IWD A;  4NV8 A;  2P7U A;  5FPW A;  2GHU A;  3C9E A;  3S3R A;  4C5P A;  3U8E A;  4NV7 A;  2OUL A;  2DCC A;  2PAD A;  1A6R A;  1MHW A;  3LXS A;  3N3G A;  3OF9 A;  7PCK A;  3HHA A;  4P6E A;  2AUX A;  4CDF B;  3NHE A;  1PPN A;  2OP3 A;  2Y6E A;  2FT2 A;  3O0U A;  2PNS A;  4X6J A;  3KWZ A;  4Q8G A;  1KFX L;  2ARY A;  1EWP A;  1W5R A;  1AU2 A;  2JQG R;  1MS6 A;  8PCH A;  5CVN B;  1KHQ A;  1TL9 A;  3IEJ A;  2DCD A;  2G7Y A;  1EWM A;  1MEG A;  3F75 A;  2DCB A;  2HD5 A;  3QJ3 A;  2VHF A;  3PNR A;  2DC8 A;  4W4U A;  3BWK A;  2YJ8 A;  3RVX A;  6PAD A;  2BDL A;  5EF4 A;  1VSN A;  1YAL A;  4B55 A;  2FTD A;  1YT7 A;  4N79 A;  4YYW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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