3LXSA

Crystal structure analysis of cruzain bound to vinyl sulfone derived inhibitor (wrr483)
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
215
structure length
215
Chain Sequence
APAAVDWRARGAVTAVKDQGQCGSCWAFSAIGNVECQWFLAGHPLTNLSEQMLVSCDKTDSGCSGGLMNNAFEWIVQENNGAVYTEDSYPYASGEGISPPCTTSGHTVGATITGHVELPQDEAQIAAWLAVNGPVAVAVDASSWMTYTGGVMTSCVSEQLDHGVLLVGYNDSAAVPYWIIKNSWTTQWGEEGYIRIAKGSNQCLVKEEASSAVVG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma cruzi
molecule keywords Cruzain
total genus 71
structure length 215
sequence length 215
chains with identical sequence C
ec nomenclature ec 3.4.22.51: Cruzipain.
pdb deposition date 2010-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3lxsA00
2E02A 1CJLA 5CVOB 4YV8A 3LFYA 4BQVA 3PNRA 1GECE 2E00A 3BC3A 1GMYA 2AU1A 1ICFA 1CSBB 2IBIA 5PADA 1CQDA 2ACTA 1QMYA 3KFQA 5JA7A 4PP1A 2R9NA 4QRVA 5FPWA 1O0EA 2AYOA 3O1GA 2DCAA 2ATOA 4YYSA 1MEGA 3BCNA 1TL9A 1PPOA 2JQGR 2YJBA 3KWBX 9PAPA 1AU2A 2PNSA 3IV2A 1BP4A 5JH3A 3BPFA 2DCCA 1PIPA 2OP3A 2G7YA 2C0YA 1SP4B 2FQ9A 1AU0A 2DJFB 5A24A 8PCHA 2HXZA 2R9CA 4WA6A 1NPZA 3CH3X 1GLOA 1K3BB 4P6EA 1F2BA 3D6SA 2WBFX 2R9FA 5CVMA 4Q8HA 1A6RA 3HWNA 4YYUA 2DZYA 1EWMA 2Y6EA 1F2AA 2CB5A 2NQDB 1PPNA 2P7UA 3KKUA 2DCDA 2VHSA 3H8BA 1KHQA 3KWZA 4DMXA 3PW3A 2JQFR 1EF7A 4BS6A 3M99A 4CZWA 1Q6KA 4XR7A 5K16A 2YJCA 2PBHA 3V6CA 3MORA 3HHIA 2VHFA 3AI8A 3K8UA 4N8WA 2OZ2A 2NQGA 3H7DA 2YJ8A 1QDQA 1PCIA 1AYUA 1AU4A 1M6DA 4X6IA 2AUXA 2XU4A 5CVNB 2AS8A 1ZCMA 2FTDA 2BDLA 3TNXA 2FO5A 4X6HA 1HUCB 2H7JA 3PDFA 5F02A 3N3GA 1YK7A 3I06A 1EWPA 1PPDA 4I04A 1QXPA 1U9XA 2DJGB 2B1NA 3P5VA 3KX1A 3E1ZB 1EWLA 1ME3A 4W4UA 1NLJA 1PE6A 2DCBA 3HD3A 3C9EA 3I3TA 1VSNA 3N4CA 1VJVA 2G6DA 4ZUXU 3WXFA 3RVVA 1MS6A 1Y4HA 2NQAA 3V6EA 1U9QX 4N79A 3BWKA 2GFOA 3KW9A 4MZSA 4CDEB 4QBBA 3PBHA 1IWDA 4OEMA 4QRGA 3KSEA 1PXVA 3P5UA 2AYNA 2E03A 1AU3A 2Y5BA 1NB5A 1XKGA 4K7CA 3H6SA 4I05A 2R9MA 4AXLA 1MHWA 1DF0A 4P6GA 1THEA 4FK5A 3U8EA 2AIMA 4MSXA 4BS5A 3MTNA 1FH0A 2P0RA 1ZIVA 4FIPA 3S3RA 4PP2E 3OF8A 1PPPA 1CV8A 1NL6A 3WXEA 3B79A 2G8JA 2XU1A 1CVZA 3P5WA 3H89A 1F2CA 3F5VA 4CDCB 2HHNA 1ITOA 4OELA 4HWYA 2XU3A 1CTEA 1BY8A 1KFXL 1YALA 2OULA 3N3KA 4DMYA 4BSQA 2AVWA 2DC7A 2PADA 2HD5A 5EF4A 3K24A 1TLOA 2PREA 4QRXA 4I07A 5CHTA 2E01A 3P5XA 5EGWA 1PBHA 3CBJA 3QT4A 1KHPA 1CS8A 1CPJA 2HH5A 3QJ3A 1S4VA 4CDFB 3CH2X 2IPPB 2XU5A 2FRQA 2YJ9A 4W5BA 1ME4A 1NB3A 1ATKA 3H8CA 3IUTA 2ARYA 4X6JA 3O0UA 4KLBA 3K9MA 4YYRA 3LXSA 4CDDB 1CB5A 2NQIA 1BQIA 3NHEA 4RY2A 3WXGA 1AYVA 1DEUA 1U9VA 7PCKA 3ZUAA 1KXRA 4QH6A 1BGOA 1YT7A 2DC8A 1STFE 2DC9A 3HHAA 1QOLA 2FT2A 2BDZA 1Y08A 3OISA 1JQPA 3IMAA 3S3QA 2R6NA 4Q8GA 6PADA 2FRAA 2F1GA 2GHUA 3ERVA 1U5IA 1YK8A 2R9OA 3F75A 3DF0A 1YVBA 1AIMA 3BPMA 4FJCA 1SNKA 2F7DA 3IOQA 4YYQA 3MHHA 1MEMA 1MIRA 4MZOA 3RVXA 4YYVA 1AECA 3RVWA 1AYWA 2B1MA 2G8EA 5CHVA 4G54A 1KFUL 3OVXA 1PADA 3BOWA 3IEJA 3IHPA 3CBKA 4AXMA 1POPA 1U9WA 4YVAA 1F29A 5J94A 3OVZA 1MDWA 1X9YA 2FYEA 2P86A 4BPVA 4XUIA 4PADA 4YYWA 2AUZA 1NQCA 2DZZA 2DC6A 1EWOA 1TU6A 3QSDA 1GCBA 2YJ2A 2CIOA 4N4ZA 4W5CA 3OF9A 3MHSA 4PI3A 3USVA 2FUDA 2O6XA 3GCBA
chains in the Genus database with same CATH superfamily
2E02A 1CJLA 5CVOB 4YV8A 3LFYA 4BQVA 3PNRA 1GECE 2E00A 4GUAA 3BC3A 1GMYA 2AU1A 3BB7A 1ICFA 1CSBB 4MM3B 2IBIA 5PADA 1CQDA 2ACTA 1QMYA 3KFQA 5JA7A 4PP1A 3BY4A 2R9NA 4QRVA 5FPWA 1O0EA 2AYOA 3O1GA 2DCAA 2ATOA 2JTCA 4YYSA 1MEGA 3BCNA 1TL9A 1PPOA 2JQGR 2YJBA 3KWBX 9PAPA 1AU2A 2PNSA 4A5UA 4RF0A 3IV2A 1BP4A 5JH3A 3BPFA 2DCCA 3TRKA 1PIPA 2OP3A 2G7YA 2C0YA 1SP4B 2FQ9A 1AU0A 2DJFB 5A24A 4MI7A 8PCHA 3PHXA 2HXZA 2J7QC 2R9CA 4WA6A 1NPZA 3CH3X 1GLOA 3MP2A 1K3BB 4P6EA 1F2BA 3D6SA 2WBFX 2DOSA 2R9FA 5CVMA 3W31A 4Q8HA 5KO3A 1A6RA 3HWNA 4YYUA 2DZYA 2BU3A 1UKFA 1EWMA 2Y6EA 3C0RA 1F2AA 2CB5A 2NQDB 1PPNA 2P7UA 3KKUA 2DCDA 2VHSA 3H8BA 1KHQA 3KWZA 4DMXA 3PW3A 2JQFR 1EF7A 3TMPA 4BS6A 3M99A 4CZWA 1DKIA 3PHUA 1Q6KA 4XR7A 5K16A 2YJCA 4IP3A 2PBHA 3V6CA 3MORA 3HHIA 2VHFA 3AI8A 3K8UA 4N8WA 2AGAA 2OZ2A 2NQGA 3B21A 3H7DA 2YJ8A 1QDQA 1PCIA 1AYUA 1AU4A 1M6DA 4X6IA 2AUXA 2XU4A 5CVNB 2AS8A 1ZCMA 2FTDA 2BDLA 4D8BA 3TNXA 1PVJA 2FO5A 4X6HA 1HUCB 2H7JA 3PDFA 4HXDB 5F02A 4OW0A 3N3GA 1YK7A 3I06A 3W30A 1EWPA 1PPDA 4I04A 1QXPA 1U9XA 2DJGB 2B1NA 3P5VA 3MTVA 4OVZB 3KX1A 3E1ZB 1EWLA 1ME3A 2BTWB 4W4UA 1NLJA 1PE6A 2DCBA 3HD3A 3C9EA 3I3TA 1VSNA 3N4CA 1VJVA 2G6DA 4ZUXU 3WXFA 3RVVA 1MS6A 1Y4HA 2NQAA 3PRMA 3V6EA 1U9QX 4N79A 3BWKA 2GFOA 3KW9A 4MZSA 4R3DA 2JRIA 4CDEB 4QBBA 3PBHA 1IWDA 3PHWA 4OEMA 4QRGA 3KSEA 1PXVA 3P5UA 2AYNA 2E03A 1AU3A 2Y5BA 1NB5A 3E9SA 1XKGA 4K7CA 3PRPA 3PT2A 3H6SA 4I05A 2R9MA 4AXLA 1MHWA 1DF0A 4P6GA 1THEA 4FK5A 3U8EA 5JZEA 2AIMA 4MSXA 4BS5A 3MTNA 4RF1A 1FH0A 2P0RA 3OQCA 1ZIVA 4XZXA 4FIPA 3S3RA 4PP2E 3OF8A 1PPPA 1CV8A 1NL6A 3WXEA 3B79A 5EZSA 2G8JA 2XU1A 1CVZA 3P5WA 4BOQA 3H89A 4RKXA 2UZJA 5E6JA 1F2CA 3BBAA 4BOZA 3F5VA 4CDCB 4OVZA 2HHNA 1ITOA 3IFUA 4OELA 4HWYA 2XU3A 2BTWA 1CTEA 1BY8A 1KFXL 4P16A 1YALA 2OULA 3N3KA 4DMYA 4BSQA 2AVWA 2DC7A 4PT5A 2PADA 2HD5A 5EF4A 2HWKA 3K24A 1TLOA 2PREA 4QRXA 4I07A 5CHTA 2E01A 3P5XA 5EGWA 1PBHA 3CBJA 3QT4A 1KHPA 1CS8A 1CPJA 2HH5A 3QJ3A 4RNAA 1S4VA 4CDFB 4REZA 3CH2X 2IPPB 2XU5A 2FRQA 2YJ9A 4W5BA 1ME4A 1NB3A 1ATKA 3H8CA 3IUTA 2ARYA 4X6JA 3O0UA 4KLBA 3K9MA 4YYRA 3LXSA 4CDDB 4BOSA 4BOPA 2J7QA 1CB5A 2NQIA 1BQIA 3NHEA 3ZNHA 4RY2A 3WXGA 1AYVA 1DEUA 1U9VA 7PCKA 3ZUAA 1KXRA 4QH6A 3RNVA 1BGOA 1YT7A 2DC8A 1STFE 2DC9A 3HHAA 1QOLA 2FT2A 2BDZA 1Y08A 3OISA 1JQPA 3IMAA 2Z84A 3S3QA 2R6NA 4Q8GA 6PADA 2FRAA 2F1GA 4IUMA 2GHUA 3ERVA 1U5IA 1YK8A 2R9OA 3O65A 3F75A 3DF0A 4D8EA 1YVBA 1AIMA 3BPMA 4FJCA 4BOUA 1SNKA 2F7DA 3IOQA 4YYQA 3MHHA 1MEMA 1MIRA 4MZOA 4ZTBA 3RVXA 4YYVA 1AECA 3RVWA 1AYWA 2B1MA 5EZQA 2G8EA 5CHVA 4G54A 1KFUL 3OVXA 1PADA 3BOWA 3IEJA 3IHPA 3CBKA 4AXMA 1POPA 1U9WA 4YVAA 1F29A 5J94A 4D8IA 3OVZA 1MDWA 4WURA 1X9YA 2FYEA 3MJ5A 2P86A 4BPVA 4M0WA 4XUIA 4PADA 4YYWA 2AUZA 1NQCA 2DZZA 2DC6A 1EWOA 1TU6A 3QSDA 1GCBA 2YJ2A 2CIOA 4N4ZA 4W5CA 3OF9A 3MHSA 4PI3A 3USVA 2FE8A 2FUDA 3PSEA 2O6XA 3GCBA 1YZBA
chains in the Genus database with same CATH topology
2E02A 1CJLA 5CVOB 4YV8A 3LFYA 4BQVA 3PNRA 1GECE 2E00A 3BC3A 1GMYA 2AU1A 1ICFA 1CSBB 2IBIA 5PADA 4GUZA 1CQDA 2ACTA 1QMYA 3KFQA 5JA7A 4PP1A 1W6FA 2R9NA 4QRVA 5FPWA 1O0EA 4C5PA 2AYOA 3O1GA 2DCAA 2ATOA 4YYSA 1MEGA 3BCNA 1TL9A 1PPOA 2JQGR 2YJBA 3KWBX 9PAPA 1AU2A 2PNSA 3IV2A 1BP4A 5JH3A 3BPFA 2DCCA 1PIPA 3LTWA 1W4TA 2OP3A 2G7YA 2C0YA 1SP4B 2FQ9A 1AU0A 2DJFB 5A24A 8PCHA 2HXZA 2R9CA 4WA6A 1NPZA 3CH3X 1GLOA 1K3BB 4P6EA 1F2BA 3D6SA 2WBFX 2R9FA 5CVMA 4Q8HA 1A6RA 3HWNA 4YYUA 2DZYA 1EWMA 2Y6EA 1F2AA 2CB5A 2NQDB 1PPNA 2P7UA 3KKUA 2DCDA 2VHSA 3H8BA 1KHQA 3KWZA 4DMXA 3PW3A 2JQFR 1EF7A 4BS6A 3M99A 4CZWA 1Q6KA 4XR7A 5K16A 2YJCA 2PBHA 3V6CA 3MORA 4BGFA 3HHIA 2VHFA 3AI8A 3K8UA 4N8WA 4NV8A 2OZ2A 2NQGA 3H7DA 2YJ8A 1QDQA 1PCIA 1AYUA 1AU4A 1M6DA 4X6IA 2AUXA 2XU4A 5CVNB 2AS8A 1ZCMA 2FTDA 2BDLA 3TNXA 2FO5A 4X6HA 1HUCB 2H7JA 3PDFA 5F02A 3N3GA 1YK7A 3I06A 1EWPA 1PPDA 3D9WA 4I04A 1QXPA 1U9XA 2DJGB 2B1NA 3P5VA 3KX1A 3E1ZB 1EWLA 1ME3A 4W4UA 1NLJA 1PE6A 2DCBA 3HD3A 3C9EA 3I3TA 1VSNA 3N4CA 1VJVA 2G6DA 4ZUXU 3WXFA 3RVVA 1MS6A 2VFCA 1Y4HA 2NQAA 3V6EA 1U9QX 4N79A 3BWKA 2GFOA 3KW9A 4MZSA 4CDEB 4QBBA 3PBHA 1IWDA 4OEMA 4QRGA 3KSEA 1PXVA 3P5UA 1E2TA 2AYNA 2E03A 1AU3A 2Y5BA 1NB5A 1XKGA 4K7CA 3H6SA 4I05A 2R9MA 4AXLA 1MHWA 1DF0A 4P6GA 1THEA 4FK5A 3U8EA 2AIMA 4MSXA 4BS5A 3MTNA 1FH0A 2P0RA 1ZIVA 4FIPA 3S3RA 4PP2E 3OF8A 1PPPA 1CV8A 1NL6A 3WXEA 3B79A 2G8JA 2XU1A 1CVZA 3P5WA 3H89A 1F2CA 3F5VA 4CDCB 2HHNA 1ITOA 4OELA 4HWYA 2XU3A 1CTEA 1BY8A 1KFXL 1YALA 2OULA 3N3KA 4DMYA 4BSQA 4B55A 2AVWA 2DC7A 2PADA 2HD5A 5EF4A 3K24A 1TLOA 2PREA 4QRXA 4I07A 5CHTA 2E01A 3P5XA 5EGWA 1PBHA 3CBJA 3QT4A 1KHPA 1CS8A 1CPJA 2HH5A 3QJ3A 1S4VA 4CDFB 3CH2X 2IPPB 2XU5A 2FRQA 2YJ9A 4W5BA 1ME4A 1NB3A 1ATKA 3H8CA 3IUTA 2ARYA 4X6JA 3O0UA 4KLBA 3K9MA 4YYRA 3LXSA 4CDDB 1CB5A 2NQIA 1BQIA 3NHEA 4RY2A 3WXGA 1AYVA 1DEUA 1U9VA 7PCKA 3ZUAA 1KXRA 1W5RA 4QH6A 1BGOA 1YT7A 2DC8A 1STFE 2DC9A 3HHAA 1QOLA 2FT2A 2BDZA 1Y08A 3OISA 1JQPA 3IMAA 3S3QA 2R6NA 4Q8GA 6PADA 2FRAA 2F1GA 2GHUA 3ERVA 1U5IA 1YK8A 1GX3A 2R9OA 3F75A 3DF0A 1YVBA 1AIMA 3BPMA 4NV7A 4FJCA 1SNKA 2F7DA 3IOQA 4YYQA 3MHHA 1MEMA 1MIRA 4MZOA 3RVXA 4YYVA 1AECA 3RVWA 1AYWA 2B1MA 2G8EA 5CHVA 4G54A 1KFUL 3OVXA 1PADA 3BOWA 3IEJA 3IHPA 3CBKA 2VFBA 4AXMA 1POPA 1U9WA 4YVAA 1F29A 5J94A 3OVZA 1MDWA 1X9YA 2FYEA 2P86A 4BPVA 4XUIA 4PADA 4YYWA 2AUZA 1NQCA 2DZZA 2DC6A 1EWOA 1TU6A 3QSDA 2BSZA 1GCBA 2YJ2A 2CIOA 4N4ZA 4W5CA 3OF9A 3MHSA 4PI3A 3USVA 2FUDA 2O6XA 3GCBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2E02 A;  1CJL A;  5CVO B;  4YV8 A;  3LFY A;  4BQV A;  3PNR A;  1GEC E;  2E00 A;  3BC3 A;  1GMY A;  2AU1 A;  1ICF A;  1CSB B;  2IBI A;  5PAD A;  1CQD A;  2ACT A;  1QMY A;  3KFQ A;  5JA7 A;  4PP1 A;  2R9N A;  4QRV A;  5FPW A;  1O0E A;  2AYO A;  3O1G A;  2DCA A;  2ATO A;  4YYS A;  1MEG A;  3BCN A;  1TL9 A;  1PPO A;  2JQG R;  2YJB A;  3KWB X;  9PAP A;  1AU2 A;  2PNS A;  3IV2 A;  1BP4 A;  5JH3 A;  3BPF A;  2DCC A;  1PIP A;  2OP3 A;  2G7Y A;  2C0Y A;  1SP4 B;  2FQ9 A;  1AU0 A;  2DJF B;  5A24 A;  8PCH A;  2HXZ A;  2R9C A;  4WA6 A;  1NPZ A;  3CH3 X;  1GLO A;  1K3B B;  4P6E A;  1F2B A;  3D6S A;  2WBF X;  2R9F A;  5CVM A;  4Q8H A;  1A6R A;  3HWN A;  4YYU A;  2DZY A;  1EWM A;  2Y6E A;  1F2A A;  2CB5 A;  2NQD B;  1PPN A;  2P7U A;  3KKU A;  2DCD A;  2VHS A;  3H8B A;  1KHQ A;  3KWZ A;  4DMX A;  3PW3 A;  2JQF R;  1EF7 A;  4BS6 A;  3M99 A;  4CZW A;  1Q6K A;  4XR7 A;  5K16 A;  2YJC A;  2PBH A;  3V6C A;  3MOR A;  3HHI A;  2VHF A;  3AI8 A;  3K8U A;  4N8W A;  2OZ2 A;  2NQG A;  3H7D A;  2YJ8 A;  1QDQ A;  1PCI A;  1AYU A;  1AU4 A;  1M6D A;  4X6I A;  2AUX A;  2XU4 A;  5CVN B;  2AS8 A;  1ZCM A;  2FTD A;  2BDL A;  3TNX A;  2FO5 A;  4X6H A;  1HUC B;  2H7J A;  3PDF A;  5F02 A;  3N3G A;  1YK7 A;  3I06 A;  1EWP A;  1PPD A;  4I04 A;  1QXP A;  1U9X A;  2DJG B;  2B1N A;  3P5V A;  3KX1 A;  3E1Z B;  1EWL A;  1ME3 A;  4W4U A;  1NLJ A;  1PE6 A;  2DCB A;  3HD3 A;  3C9E A;  3I3T A;  1VSN A;  3N4C A;  1VJV A;  2G6D A;  4ZUX U;  3WXF A;  3RVV A;  1MS6 A;  1Y4H A;  2NQA A;  3V6E A;  1U9Q X;  4N79 A;  3BWK A;  2GFO A;  3KW9 A;  4MZS A;  4CDE B;  4QBB A;  3PBH A;  1IWD A;  4OEM A;  4QRG A;  3KSE A;  1PXV A;  3P5U A;  2AYN A;  2E03 A;  1AU3 A;  2Y5B A;  1NB5 A;  1XKG A;  4K7C A;  3H6S A;  4I05 A;  2R9M A;  4AXL A;  1MHW A;  1DF0 A;  4P6G A;  1THE A;  4FK5 A;  3U8E A;  2AIM A;  4MSX A;  4BS5 A;  3MTN A;  1FH0 A;  2P0R A;  1ZIV A;  4FIP A;  3S3R A;  4PP2 E;  3OF8 A;  1PPP A;  1CV8 A;  1NL6 A;  3WXE A;  3B79 A;  2G8J A;  2XU1 A;  1CVZ A;  3P5W A;  3H89 A;  1F2C A;  3F5V A;  4CDC B;  2HHN A;  1ITO A;  4OEL A;  4HWY A;  2XU3 A;  1CTE A;  1BY8 A;  1KFX L;  1YAL A;  2OUL A;  3N3K A;  4DMY A;  4BSQ A;  2AVW A;  2DC7 A;  2PAD A;  2HD5 A;  5EF4 A;  3K24 A;  1TLO A;  2PRE A;  4QRX A;  4I07 A;  5CHT A;  2E01 A;  3P5X A;  5EGW A;  1PBH A;  3CBJ A;  3QT4 A;  1KHP A;  1CS8 A;  1CPJ A;  2HH5 A;  3QJ3 A;  1S4V A;  4CDF B;  3CH2 X;  2IPP B;  2XU5 A;  2FRQ A;  2YJ9 A;  4W5B A;  1ME4 A;  1NB3 A;  1ATK A;  3H8C A;  3IUT A;  2ARY A;  4X6J A;  3O0U A;  4KLB A;  3K9M A;  4YYR A;  3LXS A;  4CDD B;  1CB5 A;  2NQI A;  1BQI A;  3NHE A;  4RY2 A;  3WXG A;  1AYV A;  1DEU A;  1U9V A;  7PCK A;  3ZUA A;  1KXR A;  4QH6 A;  1BGO A;  1YT7 A;  2DC8 A;  1STF E;  2DC9 A;  3HHA A;  1QOL A;  2FT2 A;  2BDZ A;  1Y08 A;  3OIS A;  1JQP A;  3IMA A;  3S3Q A;  2R6N A;  4Q8G A;  6PAD A;  2FRA A;  2F1G A;  2GHU A;  3ERV A;  1U5I A;  1YK8 A;  2R9O A;  3F75 A;  3DF0 A;  1YVB A;  1AIM A;  3BPM A;  4FJC A;  1SNK A;  2F7D A;  3IOQ A;  4YYQ A;  3MHH A;  1MEM A;  1MIR A;  4MZO A;  3RVX A;  4YYV A;  1AEC A;  3RVW A;  1AYW A;  2B1M A;  2G8E A;  5CHV A;  4G54 A;  1KFU L;  3OVX A;  1PAD A;  3BOW A;  3IEJ A;  3IHP A;  3CBK A;  4AXM A;  1POP A;  1U9W A;  4YVA A;  1F29 A;  5J94 A;  3OVZ A;  1MDW A;  1X9Y A;  2FYE A;  2P86 A;  4BPV A;  4XUI A;  4PAD A;  4YYW A;  2AUZ A;  1NQC A;  2DZZ A;  2DC6 A;  1EWO A;  1TU6 A;  3QSD A;  1GCB A;  2YJ2 A;  2CIO A;  4N4Z A;  4W5C A;  3OF9 A;  3MHS A;  4PI3 A;  3USV A;  2FUD A;  2O6X A;  3GCB A; 
#chains in the Genus database with same CATH topology
 2E02 A;  1CJL A;  5CVO B;  4YV8 A;  3LFY A;  4BQV A;  3PNR A;  1GEC E;  2E00 A;  4GUA A;  3BC3 A;  1GMY A;  2AU1 A;  3BB7 A;  1ICF A;  1CSB B;  4MM3 B;  2IBI A;  5PAD A;  1CQD A;  2ACT A;  1QMY A;  3KFQ A;  5JA7 A;  4PP1 A;  3BY4 A;  2R9N A;  4QRV A;  5FPW A;  1O0E A;  2AYO A;  3O1G A;  2DCA A;  2ATO A;  2JTC A;  4YYS A;  1MEG A;  3BCN A;  1TL9 A;  1PPO A;  2JQG R;  2YJB A;  3KWB X;  9PAP A;  1AU2 A;  2PNS A;  4A5U A;  4RF0 A;  3IV2 A;  1BP4 A;  5JH3 A;  3BPF A;  2DCC A;  3TRK A;  1PIP A;  2OP3 A;  2G7Y A;  2C0Y A;  1SP4 B;  2FQ9 A;  1AU0 A;  2DJF B;  5A24 A;  4MI7 A;  8PCH A;  3PHX A;  2HXZ A;  2J7Q C;  2R9C A;  4WA6 A;  1NPZ A;  3CH3 X;  1GLO A;  3MP2 A;  1K3B B;  4P6E A;  1F2B A;  3D6S A;  2WBF X;  2DOS A;  2R9F A;  5CVM A;  3W31 A;  4Q8H A;  5KO3 A;  1A6R A;  3HWN A;  4YYU A;  2DZY A;  2BU3 A;  1UKF A;  1EWM A;  2Y6E A;  3C0R A;  1F2A A;  2CB5 A;  2NQD B;  1PPN A;  2P7U A;  3KKU A;  2DCD A;  2VHS A;  3H8B A;  1KHQ A;  3KWZ A;  4DMX A;  3PW3 A;  2JQF R;  1EF7 A;  3TMP A;  4BS6 A;  3M99 A;  4CZW A;  1DKI A;  3PHU A;  1Q6K A;  4XR7 A;  5K16 A;  2YJC A;  4IP3 A;  2PBH A;  3V6C A;  3MOR A;  3HHI A;  2VHF A;  3AI8 A;  3K8U A;  4N8W A;  2AGA A;  2OZ2 A;  2NQG A;  3B21 A;  3H7D A;  2YJ8 A;  1QDQ A;  1PCI A;  1AYU A;  1AU4 A;  1M6D A;  4X6I A;  2AUX A;  2XU4 A;  5CVN B;  2AS8 A;  1ZCM A;  2FTD A;  2BDL A;  4D8B A;  3TNX A;  1PVJ A;  2FO5 A;  4X6H A;  1HUC B;  2H7J A;  3PDF A;  4HXD B;  5F02 A;  4OW0 A;  3N3G A;  1YK7 A;  3I06 A;  3W30 A;  1EWP A;  1PPD A;  4I04 A;  1QXP A;  1U9X A;  2DJG B;  2B1N A;  3P5V A;  3MTV A;  4OVZ B;  3KX1 A;  3E1Z B;  1EWL A;  1ME3 A;  2BTW B;  4W4U A;  1NLJ A;  1PE6 A;  2DCB A;  3HD3 A;  3C9E A;  3I3T A;  1VSN A;  3N4C A;  1VJV A;  2G6D A;  4ZUX U;  3WXF A;  3RVV A;  1MS6 A;  1Y4H A;  2NQA A;  3PRM A;  3V6E A;  1U9Q X;  4N79 A;  3BWK A;  2GFO A;  3KW9 A;  4MZS A;  4R3D A;  2JRI A;  4CDE B;  4QBB A;  3PBH A;  1IWD A;  3PHW A;  4OEM A;  4QRG A;  3KSE A;  1PXV A;  3P5U A;  2AYN A;  2E03 A;  1AU3 A;  2Y5B A;  1NB5 A;  3E9S A;  1XKG A;  4K7C A;  3PRP A;  3PT2 A;  3H6S A;  4I05 A;  2R9M A;  4AXL A;  1MHW A;  1DF0 A;  4P6G A;  1THE A;  4FK5 A;  3U8E A;  5JZE A;  2AIM A;  4MSX A;  4BS5 A;  3MTN A;  4RF1 A;  1FH0 A;  2P0R A;  3OQC A;  1ZIV A;  4XZX A;  4FIP A;  3S3R A;  4PP2 E;  3OF8 A;  1PPP A;  1CV8 A;  1NL6 A;  3WXE A;  3B79 A;  5EZS A;  2G8J A;  2XU1 A;  1CVZ A;  3P5W A;  4BOQ A;  3H89 A;  4RKX A;  2UZJ A;  5E6J A;  1F2C A;  3BBA A;  4BOZ A;  3F5V A;  4CDC B;  4OVZ A;  2HHN A;  1ITO A;  3IFU A;  4OEL A;  4HWY A;  2XU3 A;  2BTW A;  1CTE A;  1BY8 A;  1KFX L;  4P16 A;  1YAL A;  2OUL A;  3N3K A;  4DMY A;  4BSQ A;  2AVW A;  2DC7 A;  4PT5 A;  2PAD A;  2HD5 A;  5EF4 A;  2HWK A;  3K24 A;  1TLO A;  2PRE A;  4QRX A;  4I07 A;  5CHT A;  2E01 A;  3P5X A;  5EGW A;  1PBH A;  3CBJ A;  3QT4 A;  1KHP A;  1CS8 A;  1CPJ A;  2HH5 A;  3QJ3 A;  4RNA A;  1S4V A;  4CDF B;  4REZ A;  3CH2 X;  2IPP B;  2XU5 A;  2FRQ A;  2YJ9 A;  4W5B A;  1ME4 A;  1NB3 A;  1ATK A;  3H8C A;  3IUT A;  2ARY A;  4X6J A;  3O0U A;  4KLB A;  3K9M A;  4YYR A;  3LXS A;  4CDD B;  4BOS A;  4BOP A;  2J7Q A;  1CB5 A;  2NQI A;  1BQI A;  3NHE A;  3ZNH A;  4RY2 A;  3WXG A;  1AYV A;  1DEU A;  1U9V A;  7PCK A;  3ZUA A;  1KXR A;  4QH6 A;  3RNV A;  1BGO A;  1YT7 A;  2DC8 A;  1STF E;  2DC9 A;  3HHA A;  1QOL A;  2FT2 A;  2BDZ A;  1Y08 A;  3OIS A;  1JQP A;  3IMA A;  2Z84 A;  3S3Q A;  2R6N A;  4Q8G A;  6PAD A;  2FRA A;  2F1G A;  4IUM A;  2GHU A;  3ERV A;  1U5I A;  1YK8 A;  2R9O A;  3O65 A;  3F75 A;  3DF0 A;  4D8E A;  1YVB A;  1AIM A;  3BPM A;  4FJC A;  4BOU A;  1SNK A;  2F7D A;  3IOQ A;  4YYQ A;  3MHH A;  1MEM A;  1MIR A;  4MZO A;  4ZTB A;  3RVX A;  4YYV A;  1AEC A;  3RVW A;  1AYW A;  2B1M A;  5EZQ A;  2G8E A;  5CHV A;  4G54 A;  1KFU L;  3OVX A;  1PAD A;  3BOW A;  3IEJ A;  3IHP A;  3CBK A;  4AXM A;  1POP A;  1U9W A;  4YVA A;  1F29 A;  5J94 A;  4D8I A;  3OVZ A;  1MDW A;  4WUR A;  1X9Y A;  2FYE A;  3MJ5 A;  2P86 A;  4BPV A;  4M0W A;  4XUI A;  4PAD A;  4YYW A;  2AUZ A;  1NQC A;  2DZZ A;  2DC6 A;  1EWO A;  1TU6 A;  3QSD A;  1GCB A;  2YJ2 A;  2CIO A;  4N4Z A;  4W5C A;  3OF9 A;  3MHS A;  4PI3 A;  3USV A;  2FE8 A;  2FUD A;  3PSE A;  2O6X A;  3GCB A;  1YZB A; 
#chains in the Genus database with same CATH homology
 2E02 A;  1CJL A;  5CVO B;  4YV8 A;  3LFY A;  4BQV A;  3PNR A;  1GEC E;  2E00 A;  3BC3 A;  1GMY A;  2AU1 A;  1ICF A;  1CSB B;  2IBI A;  5PAD A;  4GUZ A;  1CQD A;  2ACT A;  1QMY A;  3KFQ A;  5JA7 A;  4PP1 A;  1W6F A;  2R9N A;  4QRV A;  5FPW A;  1O0E A;  4C5P A;  2AYO A;  3O1G A;  2DCA A;  2ATO A;  4YYS A;  1MEG A;  3BCN A;  1TL9 A;  1PPO A;  2JQG R;  2YJB A;  3KWB X;  9PAP A;  1AU2 A;  2PNS A;  3IV2 A;  1BP4 A;  5JH3 A;  3BPF A;  2DCC A;  1PIP A;  3LTW A;  1W4T A;  2OP3 A;  2G7Y A;  2C0Y A;  1SP4 B;  2FQ9 A;  1AU0 A;  2DJF B;  5A24 A;  8PCH A;  2HXZ A;  2R9C A;  4WA6 A;  1NPZ A;  3CH3 X;  1GLO A;  1K3B B;  4P6E A;  1F2B A;  3D6S A;  2WBF X;  2R9F A;  5CVM A;  4Q8H A;  1A6R A;  3HWN A;  4YYU A;  2DZY A;  1EWM A;  2Y6E A;  1F2A A;  2CB5 A;  2NQD B;  1PPN A;  2P7U A;  3KKU A;  2DCD A;  2VHS A;  3H8B A;  1KHQ A;  3KWZ A;  4DMX A;  3PW3 A;  2JQF R;  1EF7 A;  4BS6 A;  3M99 A;  4CZW A;  1Q6K A;  4XR7 A;  5K16 A;  2YJC A;  2PBH A;  3V6C A;  3MOR A;  4BGF A;  3HHI A;  2VHF A;  3AI8 A;  3K8U A;  4N8W A;  4NV8 A;  2OZ2 A;  2NQG A;  3H7D A;  2YJ8 A;  1QDQ A;  1PCI A;  1AYU A;  1AU4 A;  1M6D A;  4X6I A;  2AUX A;  2XU4 A;  5CVN B;  2AS8 A;  1ZCM A;  2FTD A;  2BDL A;  3TNX A;  2FO5 A;  4X6H A;  1HUC B;  2H7J A;  3PDF A;  5F02 A;  3N3G A;  1YK7 A;  3I06 A;  1EWP A;  1PPD A;  3D9W A;  4I04 A;  1QXP A;  1U9X A;  2DJG B;  2B1N A;  3P5V A;  3KX1 A;  3E1Z B;  1EWL A;  1ME3 A;  4W4U A;  1NLJ A;  1PE6 A;  2DCB A;  3HD3 A;  3C9E A;  3I3T A;  1VSN A;  3N4C A;  1VJV A;  2G6D A;  4ZUX U;  3WXF A;  3RVV A;  1MS6 A;  2VFC A;  1Y4H A;  2NQA A;  3V6E A;  1U9Q X;  4N79 A;  3BWK A;  2GFO A;  3KW9 A;  4MZS A;  4CDE B;  4QBB A;  3PBH A;  1IWD A;  4OEM A;  4QRG A;  3KSE A;  1PXV A;  3P5U A;  1E2T A;  2AYN A;  2E03 A;  1AU3 A;  2Y5B A;  1NB5 A;  1XKG A;  4K7C A;  3H6S A;  4I05 A;  2R9M A;  4AXL A;  1MHW A;  1DF0 A;  4P6G A;  1THE A;  4FK5 A;  3U8E A;  2AIM A;  4MSX A;  4BS5 A;  3MTN A;  1FH0 A;  2P0R A;  1ZIV A;  4FIP A;  3S3R A;  4PP2 E;  3OF8 A;  1PPP A;  1CV8 A;  1NL6 A;  3WXE A;  3B79 A;  2G8J A;  2XU1 A;  1CVZ A;  3P5W A;  3H89 A;  1F2C A;  3F5V A;  4CDC B;  2HHN A;  1ITO A;  4OEL A;  4HWY A;  2XU3 A;  1CTE A;  1BY8 A;  1KFX L;  1YAL A;  2OUL A;  3N3K A;  4DMY A;  4BSQ A;  4B55 A;  2AVW A;  2DC7 A;  2PAD A;  2HD5 A;  5EF4 A;  3K24 A;  1TLO A;  2PRE A;  4QRX A;  4I07 A;  5CHT A;  2E01 A;  3P5X A;  5EGW A;  1PBH A;  3CBJ A;  3QT4 A;  1KHP A;  1CS8 A;  1CPJ A;  2HH5 A;  3QJ3 A;  1S4V A;  4CDF B;  3CH2 X;  2IPP B;  2XU5 A;  2FRQ A;  2YJ9 A;  4W5B A;  1ME4 A;  1NB3 A;  1ATK A;  3H8C A;  3IUT A;  2ARY A;  4X6J A;  3O0U A;  4KLB A;  3K9M A;  4YYR A;  3LXS A;  4CDD B;  1CB5 A;  2NQI A;  1BQI A;  3NHE A;  4RY2 A;  3WXG A;  1AYV A;  1DEU A;  1U9V A;  7PCK A;  3ZUA A;  1KXR A;  1W5R A;  4QH6 A;  1BGO A;  1YT7 A;  2DC8 A;  1STF E;  2DC9 A;  3HHA A;  1QOL A;  2FT2 A;  2BDZ A;  1Y08 A;  3OIS A;  1JQP A;  3IMA A;  3S3Q A;  2R6N A;  4Q8G A;  6PAD A;  2FRA A;  2F1G A;  2GHU A;  3ERV A;  1U5I A;  1YK8 A;  1GX3 A;  2R9O A;  3F75 A;  3DF0 A;  1YVB A;  1AIM A;  3BPM A;  4NV7 A;  4FJC A;  1SNK A;  2F7D A;  3IOQ A;  4YYQ A;  3MHH A;  1MEM A;  1MIR A;  4MZO A;  3RVX A;  4YYV A;  1AEC A;  3RVW A;  1AYW A;  2B1M A;  2G8E A;  5CHV A;  4G54 A;  1KFU L;  3OVX A;  1PAD A;  3BOW A;  3IEJ A;  3IHP A;  3CBK A;  2VFB A;  4AXM A;  1POP A;  1U9W A;  4YVA A;  1F29 A;  5J94 A;  3OVZ A;  1MDW A;  1X9Y A;  2FYE A;  2P86 A;  4BPV A;  4XUI A;  4PAD A;  4YYW A;  2AUZ A;  1NQC A;  2DZZ A;  2DC6 A;  1EWO A;  1TU6 A;  3QSD A;  2BSZ A;  1GCB A;  2YJ2 A;  2CIO A;  4N4Z A;  4W5C A;  3OF9 A;  3MHS A;  4PI3 A;  3USV A;  2FUD A;  2O6X A;  3GCB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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