3N3KA

The catalytic domain of usp8 in complex with a usp8 specific inhibitor
Total Genus 113
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
113
sequence length
355
structure length
355
Chain Sequence
RLSASQIRNLNPVFGGSGPALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNLLGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFLMDGLHEDLNKADNRKRYKEENNDHLDDFKAAEHAWQKHKQLNESIIVALFQGQFKSTVQCLTCHKKSRTFEAFMYLSLPLASTSKCTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSLKKIEIWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNNLKKYNLFSVSNHYGGLDGGHYTAYCKNAARQRWFKFDDHEVSDISVSSVKSSAAYILFYTSLG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A strategy for modulation of enzymes in the ubiquitin system.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Ubiquitin carboxyl-terminal hydrolase 8
total genus 113
structure length 355
sequence length 355
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2010-05-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00443 UCH Ubiquitin carboxyl-terminal hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3n3kA00
1F29A 2OP3A 3LXSA 5JH3A 5CHTA 4CDCB 2PNSA 1SP4B 1YK7A 3I3TA 1PE6A 2GFOA 3CBJA 5CVOB 3CH3X 1AYVA 1EWMA 1K3BB 2PADA 3ERVA 1TL9A 2FO5A 2DJGB 1MHWA 2P86A 4FJCA 2JQGR 3P5XA 1PPPA 1ITOA 3KFQA 4DMYA 5EGWA 3WXFA 1PCIA 1NL6A 4BQVA 3BOWA 4MZSA 2DCAA 1KHQA 5CVMA 3E1ZB 4PADA 2DC6A 2E01A 3PNRA 2ATOA 5K16A 3H8BA 1QXPA 1CV8A 3CBKA 1PPOA 1CVZA 3HD3A 1XKGA 4YYVA 4N79A 3IHPA 1AYUA 2P7UA 3HWNA 2NQDB 4YYRA 3H6SA 2FRQA 3K24A 2AVWA 3CH2X 2YJBA 4W5CA 4N4ZA 5PADA 1YVBA 1YT7A 1BGOA 1U9WA 2YJ9A 2VHFA 3H89A 1F2CA 4OELA 4PP1A 3OISA 3HHIA 1ZCMA 4XR7A 2AUZA 2F7DA 1EWPA 3P5UA 4BPVA 1AECA 3IOQA 2E03A 1ZIVA 4X6IA 4CDEB 2G7YA 4P6EA 4BS6A 1NB5A 4G54A 1AU2A 4QH6A 5CHVA 3DF0A 3PDFA 3USVA 1NB3A 1GCBA 2DJFB 3RVXA 3KSEA 2DCDA 2DC7A 1VSNA 2AS8A 2VHSA 1DEUA 2G6DA 1AU4A 1MEMA 2CB5A 3KKUA 4PI3A 4WA6A 4XUIA 2BDZA 4I04A 3MTNA 3V6CA 4AXMA 1NPZA 1KXRA 2XU1A 3BPFA 2FUDA 1EWOA 2DCCA 3LFYA 3S3RA 1BQIA 1A6RA 1YK8A 1CTEA 2HHNA 9PAPA 2AU1A 2ACTA 4CZWA 2O6XA 1MEGA 3IEJA 3P5VA 1U9VA 1MIRA 2IBIA 2FRAA 3IUTA 3N4CA 2AYNA 2H7JA 2OULA 3IV2A 2AYOA 4BSQA 3MHHA 2XU4A 1ME3A 2P0RA 3N3GA 2IPPB 4FIPA 4YVAA 1AYWA 3S3QA 3KW9A 3QJ3A 2DC8A 2FQ9A 1CB5A 3O1GA 4QRXA 2WBFX 3BWKA 4YYUA 5JA7A 2NQAA 3HHAA 1EWLA 4FK5A 4PP2E 1BP4A 1NQCA 1MS6A 2Y5BA 2XU5A 4Q8GA 1THEA 4W5BA 1MDWA 2DZYA 4I07A 2Y6EA 3D6SA 1JQPA 4HWYA 1PBHA 1KFUL 3QSDA 1CS8A 1GMYA 1STFE 2DCBA 4QBBA 1F2AA 2AIMA 2DC9A 1S4VA 2ARYA 3H8CA 4KLBA 1X9YA 3OF9A 1YALA 1PPDA 1KHPA 4Q8HA 2F1GA 2R9OA 2E00A 3KWZA 5EF4A 2G8JA 1QMYA 4CDDB 4YV8A 4K7CA 1CSBB 3M99A 3I06A 4DMXA 1KFXL 2HXZA 1QDQA 1F2BA 1Y4HA 1NLJA 1ICFA 3TNXA 3AI8A 3H7DA 4X6JA 5FPWA 1PADA 3B79A 3V6EA 1Q6KA 1POPA 4I05A 4YYWA 3BPMA 1IWDA 1HUCB 5J94A 8PCHA 1EF7A 4YYSA 3GCBA 2R9MA 4MZOA 2C0YA 1U5IA 2NQGA 2R9CA 2NQIA 3U8EA 2DZZA 1CQDA 2FYEA 4X6HA 3MHSA 1GLOA 1TU6A 4N8WA 2AUXA 5F02A 4QRVA 1BY8A 3BCNA 4QRGA 1DF0A 3P5WA 1U9XA 3C9EA 6PADA 3RVVA 3OVXA 5A24A 3F75A 4BS5A 2FT2A 3PBHA 2B1NA 4W4UA 1SNKA 3IMAA 2FTDA 3PW3A 3K9MA 3MORA 3NHEA 3O0UA 1PPNA 1TLOA 2YJCA 1Y08A 2CIOA 2JQFR 1U9QX 3K8UA 4RY2A 5CVNB 1AIMA 4YYQA 1M6DA 1PIPA 3WXEA 2R9NA 2BDLA 2GHUA 3ZUAA 1AU0A 1FH0A 1ME4A 2B1MA 2PREA 4MSXA 2XU3A 1PXVA 1CPJA 2R9FA 1ATKA 4ZUXU 2HH5A 2G8EA 3KWBX 1QOLA 1O0EA 4P6GA 2HD5A 3RVWA 3QT4A 3N3KA 1GECE 3KX1A 3OVZA 2PBHA 4AXLA 1AU3A 2YJ2A 3F5VA 3WXGA 1CJLA 3OF8A 4OEMA 2R6NA 7PCKA 1VJVA 2E02A 2YJ8A 4CDFB 2OZ2A 3BC3A
chains in the Genus database with same CATH superfamily
1F29A 2OP3A 3LXSA 5JH3A 5CHTA 4CDCB 2PNSA 1SP4B 1YK7A 3I3TA 2BTWB 3MJ5A 1PE6A 2GFOA 3CBJA 1DKIA 4MM3B 5CVOB 3CH3X 1AYVA 1EWMA 1K3BB 2PADA 3ERVA 1TL9A 2FO5A 2DJGB 1MHWA 2P86A 3PHWA 4FJCA 2JQGR 3P5XA 1PPPA 1ITOA 3KFQA 4DMYA 5EGWA 3WXFA 1PCIA 1NL6A 4BQVA 3BOWA 4MZSA 2DCAA 1KHQA 5CVMA 3E1ZB 4PADA 2DC6A 2E01A 3PNRA 2ATOA 4PT5A 5K16A 3H8BA 1QXPA 1CV8A 3BBAA 3CBKA 1PPOA 1CVZA 3HD3A 1XKGA 2JRIA 3E9SA 4YYVA 4N79A 4GUAA 3IHPA 1AYUA 2P7UA 3HWNA 2NQDB 4YYRA 3H6SA 2FRQA 3K24A 2AGAA 2AVWA 3CH2X 3TMPA 2YJBA 4W5CA 4N4ZA 5PADA 4RNAA 1YVBA 1YZBA 1YT7A 1BGOA 1U9WA 4ZTBA 2YJ9A 2VHFA 3H89A 1F2CA 4OELA 4PP1A 3OISA 3HHIA 1ZCMA 4MI7A 4XR7A 2AUZA 2F7DA 1EWPA 3P5UA 4BPVA 1AECA 3IOQA 2E03A 1ZIVA 4X6IA 4CDEB 4BOQA 2G7YA 4P6EA 4BS6A 1NB5A 4G54A 4D8EA 1AU2A 4QH6A 3MP2A 5CHVA 3IFUA 3DF0A 4IUMA 3PDFA 3USVA 4BOUA 1NB3A 1GCBA 2DJFB 3RVXA 4OW0A 3KSEA 2DCDA 2DC7A 2JTCA 1VSNA 2AS8A 3TRKA 2VHSA 1DEUA 2G6DA 1AU4A 4BOZA 1MEMA 2CB5A 3KKUA 3PSEA 4PI3A 4WA6A 4XUIA 2BDZA 4I04A 3MTNA 3V6CA 4AXMA 1NPZA 1KXRA 4P16A 2XU1A 3BPFA 2FUDA 3BB7A 1EWOA 2DCCA 3LFYA 3S3RA 1BQIA 1A6RA 3MTVA 1YK8A 3C0RA 1CTEA 2HHNA 9PAPA 2AU1A 2ACTA 4CZWA 2O6XA 1MEGA 3IEJA 3P5VA 1U9VA 1MIRA 2IBIA 2FRAA 3IUTA 3N4CA 2AYNA 2H7JA 2OULA 3IV2A 2AYOA 4BSQA 3MHHA 2XU4A 1ME3A 2P0RA 3N3GA 2IPPB 4FIPA 4YVAA 4OVZA 1AYWA 3W31A 2J7QC 3S3QA 3KW9A 5EZQA 3QJ3A 2DC8A 2FQ9A 1CB5A 3O1GA 4QRXA 2WBFX 3BWKA 2UZJA 4YYUA 5JA7A 2NQAA 3HHAA 1EWLA 4FK5A 4PP2E 1BP4A 2DOSA 4D8BA 5KO3A 1NQCA 1MS6A 2Y5BA 2XU5A 4Q8GA 4RF1A 1THEA 4W5BA 1MDWA 3B21A 2DZYA 4I07A 2Y6EA 3PT2A 3D6SA 1JQPA 4HWYA 1PBHA 1KFUL 3QSDA 1CS8A 1GMYA 2Z84A 1STFE 2DCBA 4QBBA 1F2AA 2AIMA 4M0WA 4XZXA 2DC9A 1S4VA 2ARYA 3H8CA 4KLBA 1X9YA 2J7QA 1UKFA 3BY4A 5JZEA 3OF9A 4OVZB 1YALA 1PPDA 1KHPA 4BOPA 4Q8HA 3RNVA 2F1GA 3KWZA 2E00A 2R9OA 5EF4A 4IP3A 4RKXA 2G8JA 1QMYA 4CDDB 4YV8A 4K7CA 1CSBB 3M99A 3I06A 3PRPA 4DMXA 1KFXL 2HXZA 1QDQA 1F2BA 1Y4HA 1NLJA 1ICFA 3TNXA 3AI8A 3H7DA 4X6JA 5FPWA 1PADA 3B79A 3V6EA 1Q6KA 1POPA 4I05A 4YYWA 3BPMA 1IWDA 1HUCB 5J94A 8PCHA 1EF7A 4YYSA 3GCBA 3PRMA 2R9MA 4MZOA 2C0YA 1U5IA 2NQGA 2R9CA 2NQIA 3U8EA 2DZZA 1CQDA 2FYEA 4X6HA 3MHSA 2HWKA 1GLOA 1TU6A 4N8WA 2AUXA 5F02A 4QRVA 1BY8A 3BCNA 3OQCA 4QRGA 1DF0A 3P5WA 1U9XA 3C9EA 3W30A 3PHXA 6PADA 3RVVA 3OVXA 5A24A 3F75A 4BS5A 4RF0A 2FT2A 3ZNHA 3PBHA 2B1NA 4W4UA 1SNKA 3IMAA 2FTDA 4R3DA 3PW3A 3K9MA 3MORA 3NHEA 3O0UA 1PVJA 1PPNA 1TLOA 2YJCA 2BU3A 1Y08A 2CIOA 2BTWA 2JQFR 5EZSA 1U9QX 3K8UA 4RY2A 5CVNB 1AIMA 4YYQA 1M6DA 1PIPA 3O65A 3WXEA 2R9NA 5E6JA 2BDLA 2GHUA 3ZUAA 1AU0A 1FH0A 1ME4A 2B1MA 2PREA 4MSXA 2XU3A 1PXVA 1CPJA 2R9FA 1ATKA 4ZUXU 2HH5A 2G8EA 3KWBX 4HXDB 1QOLA 1O0EA 4P6GA 4D8IA 2HD5A 3RVWA 4BOSA 3QT4A 3N3KA 1GECE 3KX1A 3OVZA 2PBHA 4AXLA 1AU3A 2YJ2A 3F5VA 4REZA 4WURA 3WXGA 1CJLA 3OF8A 3PHUA 4OEMA 2R6NA 2FE8A 7PCKA 1VJVA 2E02A 4A5UA 2YJ8A 4CDFB 2OZ2A 3BC3A
chains in the Genus database with same CATH topology
1F29A 2OP3A 3LXSA 5JH3A 5CHTA 4CDCB 2PNSA 1SP4B 1YK7A 3I3TA 1PE6A 2GFOA 3CBJA 5CVOB 2VFBA 3CH3X 1AYVA 1EWMA 1K3BB 2PADA 3ERVA 1TL9A 2FO5A 2DJGB 1MHWA 2P86A 4FJCA 2JQGR 3P5XA 1PPPA 1ITOA 3KFQA 4DMYA 5EGWA 3WXFA 1PCIA 1NL6A 4BQVA 3BOWA 4MZSA 2DCAA 1W6FA 1KHQA 5CVMA 3E1ZB 4PADA 2DC6A 4B55A 2E01A 3PNRA 2ATOA 5K16A 3H8BA 1QXPA 4GUZA 1CV8A 3CBKA 1PPOA 1CVZA 3HD3A 1XKGA 4YYVA 4N79A 3IHPA 1AYUA 2P7UA 3HWNA 2NQDB 4YYRA 3H6SA 2FRQA 3K24A 2AVWA 3CH2X 1W4TA 2YJBA 4W5CA 4N4ZA 5PADA 2VFCA 1YVBA 1YT7A 1BGOA 1E2TA 1U9WA 3D9WA 2YJ9A 2VHFA 3H89A 1F2CA 4OELA 4PP1A 3OISA 3HHIA 1ZCMA 4XR7A 2AUZA 2F7DA 1EWPA 3P5UA 4BPVA 1AECA 3IOQA 2E03A 1ZIVA 4X6IA 4CDEB 2G7YA 4P6EA 4BS6A 1NB5A 4G54A 1W5RA 1AU2A 4QH6A 5CHVA 3DF0A 3PDFA 3USVA 1NB3A 1GCBA 1GX3A 2DJFB 3RVXA 3KSEA 2DCDA 2DC7A 1VSNA 2AS8A 2VHSA 1DEUA 2G6DA 1AU4A 1MEMA 2CB5A 3KKUA 4PI3A 4WA6A 4XUIA 2BDZA 4I04A 3MTNA 3V6CA 4AXMA 1NPZA 1KXRA 2XU1A 3BPFA 2FUDA 1EWOA 2DCCA 3LFYA 3S3RA 1BQIA 3LTWA 1A6RA 1YK8A 1CTEA 4NV7A 2HHNA 9PAPA 2AU1A 2ACTA 4CZWA 2O6XA 1MEGA 3IEJA 3P5VA 1U9VA 1MIRA 2IBIA 2FRAA 3IUTA 3N4CA 2AYNA 2H7JA 2OULA 3IV2A 2AYOA 4BSQA 3MHHA 2XU4A 1ME3A 2P0RA 3N3GA 2IPPB 4FIPA 4YVAA 1AYWA 3S3QA 3KW9A 3QJ3A 2DC8A 2FQ9A 1CB5A 3O1GA 4QRXA 2WBFX 3BWKA 4YYUA 5JA7A 2NQAA 3HHAA 1EWLA 4FK5A 4PP2E 1BP4A 1NQCA 1MS6A 2Y5BA 2XU5A 4Q8GA 1THEA 4W5BA 1MDWA 2DZYA 4I07A 2Y6EA 3D6SA 1JQPA 4HWYA 1PBHA 1KFUL 3QSDA 1CS8A 1GMYA 1STFE 2DCBA 4QBBA 4NV8A 1F2AA 2AIMA 2DC9A 4KLBA 1S4VA 2ARYA 3H8CA 1X9YA 3OF9A 1YALA 1PPDA 1KHPA 4Q8HA 2BSZA 2F1GA 2R9OA 2E00A 3KWZA 5EF4A 2G8JA 1QMYA 4CDDB 4YV8A 4K7CA 4C5PA 1CSBB 3M99A 3I06A 4DMXA 1KFXL 2HXZA 1QDQA 1F2BA 1Y4HA 1NLJA 1ICFA 3TNXA 4BGFA 3AI8A 3H7DA 4X6JA 5FPWA 1PADA 3B79A 3V6EA 1Q6KA 1POPA 4I05A 4YYWA 3BPMA 1IWDA 1HUCB 5J94A 8PCHA 1EF7A 4YYSA 3GCBA 2R9MA 4MZOA 2C0YA 1U5IA 2NQGA 2R9CA 2NQIA 3U8EA 2DZZA 1CQDA 2FYEA 4X6HA 3MHSA 1GLOA 1TU6A 4N8WA 2AUXA 5F02A 4QRVA 1BY8A 3BCNA 4QRGA 1DF0A 3P5WA 1U9XA 3C9EA 6PADA 3RVVA 3OVXA 5A24A 3F75A 4BS5A 2FT2A 3PBHA 2B1NA 4W4UA 1SNKA 3IMAA 2FTDA 3PW3A 3K9MA 3MORA 3NHEA 3O0UA 1PPNA 1TLOA 2YJCA 1Y08A 2CIOA 2JQFR 1U9QX 3K8UA 4RY2A 5CVNB 1AIMA 4YYQA 1M6DA 1PIPA 3WXEA 2R9NA 2BDLA 2GHUA 3ZUAA 1AU0A 1FH0A 1ME4A 2B1MA 2PREA 4MSXA 2XU3A 1PXVA 1CPJA 2R9FA 1ATKA 4ZUXU 2HH5A 2G8EA 3KWBX 1QOLA 1O0EA 4P6GA 2HD5A 3RVWA 3QT4A 3N3KA 1GECE 3KX1A 3OVZA 2PBHA 4AXLA 1AU3A 2YJ2A 3F5VA 3WXGA 1CJLA 3OF8A 4OEMA 2R6NA 7PCKA 1VJVA 2E02A 2YJ8A 4CDFB 2OZ2A 3BC3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F29 A;  2OP3 A;  3LXS A;  5JH3 A;  5CHT A;  4CDC B;  2PNS A;  1SP4 B;  1YK7 A;  3I3T A;  1PE6 A;  2GFO A;  3CBJ A;  5CVO B;  3CH3 X;  1AYV A;  1EWM A;  1K3B B;  2PAD A;  3ERV A;  1TL9 A;  2FO5 A;  2DJG B;  1MHW A;  2P86 A;  4FJC A;  2JQG R;  3P5X A;  1PPP A;  1ITO A;  3KFQ A;  4DMY A;  5EGW A;  3WXF A;  1PCI A;  1NL6 A;  4BQV A;  3BOW A;  4MZS A;  2DCA A;  1KHQ A;  5CVM A;  3E1Z B;  4PAD A;  2DC6 A;  2E01 A;  3PNR A;  2ATO A;  5K16 A;  3H8B A;  1QXP A;  1CV8 A;  3CBK A;  1PPO A;  1CVZ A;  3HD3 A;  1XKG A;  4YYV A;  4N79 A;  3IHP A;  1AYU A;  2P7U A;  3HWN A;  2NQD B;  4YYR A;  3H6S A;  2FRQ A;  3K24 A;  2AVW A;  3CH2 X;  2YJB A;  4W5C A;  4N4Z A;  5PAD A;  1YVB A;  1YT7 A;  1BGO A;  1U9W A;  2YJ9 A;  2VHF A;  3H89 A;  1F2C A;  4OEL A;  4PP1 A;  3OIS A;  3HHI A;  1ZCM A;  4XR7 A;  2AUZ A;  2F7D A;  1EWP A;  3P5U A;  4BPV A;  1AEC A;  3IOQ A;  2E03 A;  1ZIV A;  4X6I A;  4CDE B;  2G7Y A;  4P6E A;  4BS6 A;  1NB5 A;  4G54 A;  1AU2 A;  4QH6 A;  5CHV A;  3DF0 A;  3PDF A;  3USV A;  1NB3 A;  1GCB A;  2DJF B;  3RVX A;  3KSE A;  2DCD A;  2DC7 A;  1VSN A;  2AS8 A;  2VHS A;  1DEU A;  2G6D A;  1AU4 A;  1MEM A;  2CB5 A;  3KKU A;  4PI3 A;  4WA6 A;  4XUI A;  2BDZ A;  4I04 A;  3MTN A;  3V6C A;  4AXM A;  1NPZ A;  1KXR A;  2XU1 A;  3BPF A;  2FUD A;  1EWO A;  2DCC A;  3LFY A;  3S3R A;  1BQI A;  1A6R A;  1YK8 A;  1CTE A;  2HHN A;  9PAP A;  2AU1 A;  2ACT A;  4CZW A;  2O6X A;  1MEG A;  3IEJ A;  3P5V A;  1U9V A;  1MIR A;  2IBI A;  2FRA A;  3IUT A;  3N4C A;  2AYN A;  2H7J A;  2OUL A;  3IV2 A;  2AYO A;  4BSQ A;  3MHH A;  2XU4 A;  1ME3 A;  2P0R A;  3N3G A;  2IPP B;  4FIP A;  4YVA A;  1AYW A;  3S3Q A;  3KW9 A;  3QJ3 A;  2DC8 A;  2FQ9 A;  1CB5 A;  3O1G A;  4QRX A;  2WBF X;  3BWK A;  4YYU A;  5JA7 A;  2NQA A;  3HHA A;  1EWL A;  4FK5 A;  4PP2 E;  1BP4 A;  1NQC A;  1MS6 A;  2Y5B A;  2XU5 A;  4Q8G A;  1THE A;  4W5B A;  1MDW A;  2DZY A;  4I07 A;  2Y6E A;  3D6S A;  1JQP A;  4HWY A;  1PBH A;  1KFU L;  3QSD A;  1CS8 A;  1GMY A;  1STF E;  2DCB A;  4QBB A;  1F2A A;  2AIM A;  2DC9 A;  1S4V A;  2ARY A;  3H8C A;  4KLB A;  1X9Y A;  3OF9 A;  1YAL A;  1PPD A;  1KHP A;  4Q8H A;  2F1G A;  2R9O A;  2E00 A;  3KWZ A;  5EF4 A;  2G8J A;  1QMY A;  4CDD B;  4YV8 A;  4K7C A;  1CSB B;  3M99 A;  3I06 A;  4DMX A;  1KFX L;  2HXZ A;  1QDQ A;  1F2B A;  1Y4H A;  1NLJ A;  1ICF A;  3TNX A;  3AI8 A;  3H7D A;  4X6J A;  5FPW A;  1PAD A;  3B79 A;  3V6E A;  1Q6K A;  1POP A;  4I05 A;  4YYW A;  3BPM A;  1IWD A;  1HUC B;  5J94 A;  8PCH A;  1EF7 A;  4YYS A;  3GCB A;  2R9M A;  4MZO A;  2C0Y A;  1U5I A;  2NQG A;  2R9C A;  2NQI A;  3U8E A;  2DZZ A;  1CQD A;  2FYE A;  4X6H A;  3MHS A;  1GLO A;  1TU6 A;  4N8W A;  2AUX A;  5F02 A;  4QRV A;  1BY8 A;  3BCN A;  4QRG A;  1DF0 A;  3P5W A;  1U9X A;  3C9E A;  6PAD A;  3RVV A;  3OVX A;  5A24 A;  3F75 A;  4BS5 A;  2FT2 A;  3PBH A;  2B1N A;  4W4U A;  1SNK A;  3IMA A;  2FTD A;  3PW3 A;  3K9M A;  3MOR A;  3NHE A;  3O0U A;  1PPN A;  1TLO A;  2YJC A;  1Y08 A;  2CIO A;  2JQF R;  1U9Q X;  3K8U A;  4RY2 A;  5CVN B;  1AIM A;  4YYQ A;  1M6D A;  1PIP A;  3WXE A;  2R9N A;  2BDL A;  2GHU A;  3ZUA A;  1AU0 A;  1FH0 A;  1ME4 A;  2B1M A;  2PRE A;  4MSX A;  2XU3 A;  1PXV A;  1CPJ A;  2R9F A;  1ATK A;  4ZUX U;  2HH5 A;  2G8E A;  3KWB X;  1QOL A;  1O0E A;  4P6G A;  2HD5 A;  3RVW A;  3QT4 A;  3N3K A;  1GEC E;  3KX1 A;  3OVZ A;  2PBH A;  4AXL A;  1AU3 A;  2YJ2 A;  3F5V A;  3WXG A;  1CJL A;  3OF8 A;  4OEM A;  2R6N A;  7PCK A;  1VJV A;  2E02 A;  2YJ8 A;  4CDF B;  2OZ2 A;  3BC3 A; 
#chains in the Genus database with same CATH topology
 1F29 A;  2OP3 A;  3LXS A;  5JH3 A;  5CHT A;  4CDC B;  2PNS A;  1SP4 B;  1YK7 A;  3I3T A;  2BTW B;  3MJ5 A;  1PE6 A;  2GFO A;  3CBJ A;  1DKI A;  4MM3 B;  5CVO B;  3CH3 X;  1AYV A;  1EWM A;  1K3B B;  2PAD A;  3ERV A;  1TL9 A;  2FO5 A;  2DJG B;  1MHW A;  2P86 A;  3PHW A;  4FJC A;  2JQG R;  3P5X A;  1PPP A;  1ITO A;  3KFQ A;  4DMY A;  5EGW A;  3WXF A;  1PCI A;  1NL6 A;  4BQV A;  3BOW A;  4MZS A;  2DCA A;  1KHQ A;  5CVM A;  3E1Z B;  4PAD A;  2DC6 A;  2E01 A;  3PNR A;  2ATO A;  4PT5 A;  5K16 A;  3H8B A;  1QXP A;  1CV8 A;  3BBA A;  3CBK A;  1PPO A;  1CVZ A;  3HD3 A;  1XKG A;  2JRI A;  3E9S A;  4YYV A;  4N79 A;  4GUA A;  3IHP A;  1AYU A;  2P7U A;  3HWN A;  2NQD B;  4YYR A;  3H6S A;  2FRQ A;  3K24 A;  2AGA A;  2AVW A;  3CH2 X;  3TMP A;  2YJB A;  4W5C A;  4N4Z A;  5PAD A;  4RNA A;  1YVB A;  1YZB A;  1YT7 A;  1BGO A;  1U9W A;  4ZTB A;  2YJ9 A;  2VHF A;  3H89 A;  1F2C A;  4OEL A;  4PP1 A;  3OIS A;  3HHI A;  1ZCM A;  4MI7 A;  4XR7 A;  2AUZ A;  2F7D A;  1EWP A;  3P5U A;  4BPV A;  1AEC A;  3IOQ A;  2E03 A;  1ZIV A;  4X6I A;  4CDE B;  4BOQ A;  2G7Y A;  4P6E A;  4BS6 A;  1NB5 A;  4G54 A;  4D8E A;  1AU2 A;  4QH6 A;  3MP2 A;  5CHV A;  3IFU A;  3DF0 A;  4IUM A;  3PDF A;  3USV A;  4BOU A;  1NB3 A;  1GCB A;  2DJF B;  3RVX A;  4OW0 A;  3KSE A;  2DCD A;  2DC7 A;  2JTC A;  1VSN A;  2AS8 A;  3TRK A;  2VHS A;  1DEU A;  2G6D A;  1AU4 A;  4BOZ A;  1MEM A;  2CB5 A;  3KKU A;  3PSE A;  4PI3 A;  4WA6 A;  4XUI A;  2BDZ A;  4I04 A;  3MTN A;  3V6C A;  4AXM A;  1NPZ A;  1KXR A;  4P16 A;  2XU1 A;  3BPF A;  2FUD A;  3BB7 A;  1EWO A;  2DCC A;  3LFY A;  3S3R A;  1BQI A;  1A6R A;  3MTV A;  1YK8 A;  3C0R A;  1CTE A;  2HHN A;  9PAP A;  2AU1 A;  2ACT A;  4CZW A;  2O6X A;  1MEG A;  3IEJ A;  3P5V A;  1U9V A;  1MIR A;  2IBI A;  2FRA A;  3IUT A;  3N4C A;  2AYN A;  2H7J A;  2OUL A;  3IV2 A;  2AYO A;  4BSQ A;  3MHH A;  2XU4 A;  1ME3 A;  2P0R A;  3N3G A;  2IPP B;  4FIP A;  4YVA A;  4OVZ A;  1AYW A;  3W31 A;  2J7Q C;  3S3Q A;  3KW9 A;  5EZQ A;  3QJ3 A;  2DC8 A;  2FQ9 A;  1CB5 A;  3O1G A;  4QRX A;  2WBF X;  3BWK A;  2UZJ A;  4YYU A;  5JA7 A;  2NQA A;  3HHA A;  1EWL A;  4FK5 A;  4PP2 E;  1BP4 A;  2DOS A;  4D8B A;  5KO3 A;  1NQC A;  1MS6 A;  2Y5B A;  2XU5 A;  4Q8G A;  4RF1 A;  1THE A;  4W5B A;  1MDW A;  3B21 A;  2DZY A;  4I07 A;  2Y6E A;  3PT2 A;  3D6S A;  1JQP A;  4HWY A;  1PBH A;  1KFU L;  3QSD A;  1CS8 A;  1GMY A;  2Z84 A;  1STF E;  2DCB A;  4QBB A;  1F2A A;  2AIM A;  4M0W A;  4XZX A;  2DC9 A;  1S4V A;  2ARY A;  3H8C A;  4KLB A;  1X9Y A;  2J7Q A;  1UKF A;  3BY4 A;  5JZE A;  3OF9 A;  4OVZ B;  1YAL A;  1PPD A;  1KHP A;  4BOP A;  4Q8H A;  3RNV A;  2F1G A;  3KWZ A;  2E00 A;  2R9O A;  5EF4 A;  4IP3 A;  4RKX A;  2G8J A;  1QMY A;  4CDD B;  4YV8 A;  4K7C A;  1CSB B;  3M99 A;  3I06 A;  3PRP A;  4DMX A;  1KFX L;  2HXZ A;  1QDQ A;  1F2B A;  1Y4H A;  1NLJ A;  1ICF A;  3TNX A;  3AI8 A;  3H7D A;  4X6J A;  5FPW A;  1PAD A;  3B79 A;  3V6E A;  1Q6K A;  1POP A;  4I05 A;  4YYW A;  3BPM A;  1IWD A;  1HUC B;  5J94 A;  8PCH A;  1EF7 A;  4YYS A;  3GCB A;  3PRM A;  2R9M A;  4MZO A;  2C0Y A;  1U5I A;  2NQG A;  2R9C A;  2NQI A;  3U8E A;  2DZZ A;  1CQD A;  2FYE A;  4X6H A;  3MHS A;  2HWK A;  1GLO A;  1TU6 A;  4N8W A;  2AUX A;  5F02 A;  4QRV A;  1BY8 A;  3BCN A;  3OQC A;  4QRG A;  1DF0 A;  3P5W A;  1U9X A;  3C9E A;  3W30 A;  3PHX A;  6PAD A;  3RVV A;  3OVX A;  5A24 A;  3F75 A;  4BS5 A;  4RF0 A;  2FT2 A;  3ZNH A;  3PBH A;  2B1N A;  4W4U A;  1SNK A;  3IMA A;  2FTD A;  4R3D A;  3PW3 A;  3K9M A;  3MOR A;  3NHE A;  3O0U A;  1PVJ A;  1PPN A;  1TLO A;  2YJC A;  2BU3 A;  1Y08 A;  2CIO A;  2BTW A;  2JQF R;  5EZS A;  1U9Q X;  3K8U A;  4RY2 A;  5CVN B;  1AIM A;  4YYQ A;  1M6D A;  1PIP A;  3O65 A;  3WXE A;  2R9N A;  5E6J A;  2BDL A;  2GHU A;  3ZUA A;  1AU0 A;  1FH0 A;  1ME4 A;  2B1M A;  2PRE A;  4MSX A;  2XU3 A;  1PXV A;  1CPJ A;  2R9F A;  1ATK A;  4ZUX U;  2HH5 A;  2G8E A;  3KWB X;  4HXD B;  1QOL A;  1O0E A;  4P6G A;  4D8I A;  2HD5 A;  3RVW A;  4BOS A;  3QT4 A;  3N3K A;  1GEC E;  3KX1 A;  3OVZ A;  2PBH A;  4AXL A;  1AU3 A;  2YJ2 A;  3F5V A;  4REZ A;  4WUR A;  3WXG A;  1CJL A;  3OF8 A;  3PHU A;  4OEM A;  2R6N A;  2FE8 A;  7PCK A;  1VJV A;  2E02 A;  4A5U A;  2YJ8 A;  4CDF B;  2OZ2 A;  3BC3 A; 
#chains in the Genus database with same CATH homology
 1F29 A;  2OP3 A;  3LXS A;  5JH3 A;  5CHT A;  4CDC B;  2PNS A;  1SP4 B;  1YK7 A;  3I3T A;  1PE6 A;  2GFO A;  3CBJ A;  5CVO B;  2VFB A;  3CH3 X;  1AYV A;  1EWM A;  1K3B B;  2PAD A;  3ERV A;  1TL9 A;  2FO5 A;  2DJG B;  1MHW A;  2P86 A;  4FJC A;  2JQG R;  3P5X A;  1PPP A;  1ITO A;  3KFQ A;  4DMY A;  5EGW A;  3WXF A;  1PCI A;  1NL6 A;  4BQV A;  3BOW A;  4MZS A;  2DCA A;  1W6F A;  1KHQ A;  5CVM A;  3E1Z B;  4PAD A;  2DC6 A;  4B55 A;  2E01 A;  3PNR A;  2ATO A;  5K16 A;  3H8B A;  1QXP A;  4GUZ A;  1CV8 A;  3CBK A;  1PPO A;  1CVZ A;  3HD3 A;  1XKG A;  4YYV A;  4N79 A;  3IHP A;  1AYU A;  2P7U A;  3HWN A;  2NQD B;  4YYR A;  3H6S A;  2FRQ A;  3K24 A;  2AVW A;  3CH2 X;  1W4T A;  2YJB A;  4W5C A;  4N4Z A;  5PAD A;  2VFC A;  1YVB A;  1YT7 A;  1BGO A;  1E2T A;  1U9W A;  3D9W A;  2YJ9 A;  2VHF A;  3H89 A;  1F2C A;  4OEL A;  4PP1 A;  3OIS A;  3HHI A;  1ZCM A;  4XR7 A;  2AUZ A;  2F7D A;  1EWP A;  3P5U A;  4BPV A;  1AEC A;  3IOQ A;  2E03 A;  1ZIV A;  4X6I A;  4CDE B;  2G7Y A;  4P6E A;  4BS6 A;  1NB5 A;  4G54 A;  1W5R A;  1AU2 A;  4QH6 A;  5CHV A;  3DF0 A;  3PDF A;  3USV A;  1NB3 A;  1GCB A;  1GX3 A;  2DJF B;  3RVX A;  3KSE A;  2DCD A;  2DC7 A;  1VSN A;  2AS8 A;  2VHS A;  1DEU A;  2G6D A;  1AU4 A;  1MEM A;  2CB5 A;  3KKU A;  4PI3 A;  4WA6 A;  4XUI A;  2BDZ A;  4I04 A;  3MTN A;  3V6C A;  4AXM A;  1NPZ A;  1KXR A;  2XU1 A;  3BPF A;  2FUD A;  1EWO A;  2DCC A;  3LFY A;  3S3R A;  1BQI A;  3LTW A;  1A6R A;  1YK8 A;  1CTE A;  4NV7 A;  2HHN A;  9PAP A;  2AU1 A;  2ACT A;  4CZW A;  2O6X A;  1MEG A;  3IEJ A;  3P5V A;  1U9V A;  1MIR A;  2IBI A;  2FRA A;  3IUT A;  3N4C A;  2AYN A;  2H7J A;  2OUL A;  3IV2 A;  2AYO A;  4BSQ A;  3MHH A;  2XU4 A;  1ME3 A;  2P0R A;  3N3G A;  2IPP B;  4FIP A;  4YVA A;  1AYW A;  3S3Q A;  3KW9 A;  3QJ3 A;  2DC8 A;  2FQ9 A;  1CB5 A;  3O1G A;  4QRX A;  2WBF X;  3BWK A;  4YYU A;  5JA7 A;  2NQA A;  3HHA A;  1EWL A;  4FK5 A;  4PP2 E;  1BP4 A;  1NQC A;  1MS6 A;  2Y5B A;  2XU5 A;  4Q8G A;  1THE A;  4W5B A;  1MDW A;  2DZY A;  4I07 A;  2Y6E A;  3D6S A;  1JQP A;  4HWY A;  1PBH A;  1KFU L;  3QSD A;  1CS8 A;  1GMY A;  1STF E;  2DCB A;  4QBB A;  4NV8 A;  1F2A A;  2AIM A;  2DC9 A;  4KLB A;  1S4V A;  2ARY A;  3H8C A;  1X9Y A;  3OF9 A;  1YAL A;  1PPD A;  1KHP A;  4Q8H A;  2BSZ A;  2F1G A;  2R9O A;  2E00 A;  3KWZ A;  5EF4 A;  2G8J A;  1QMY A;  4CDD B;  4YV8 A;  4K7C A;  4C5P A;  1CSB B;  3M99 A;  3I06 A;  4DMX A;  1KFX L;  2HXZ A;  1QDQ A;  1F2B A;  1Y4H A;  1NLJ A;  1ICF A;  3TNX A;  4BGF A;  3AI8 A;  3H7D A;  4X6J A;  5FPW A;  1PAD A;  3B79 A;  3V6E A;  1Q6K A;  1POP A;  4I05 A;  4YYW A;  3BPM A;  1IWD A;  1HUC B;  5J94 A;  8PCH A;  1EF7 A;  4YYS A;  3GCB A;  2R9M A;  4MZO A;  2C0Y A;  1U5I A;  2NQG A;  2R9C A;  2NQI A;  3U8E A;  2DZZ A;  1CQD A;  2FYE A;  4X6H A;  3MHS A;  1GLO A;  1TU6 A;  4N8W A;  2AUX A;  5F02 A;  4QRV A;  1BY8 A;  3BCN A;  4QRG A;  1DF0 A;  3P5W A;  1U9X A;  3C9E A;  6PAD A;  3RVV A;  3OVX A;  5A24 A;  3F75 A;  4BS5 A;  2FT2 A;  3PBH A;  2B1N A;  4W4U A;  1SNK A;  3IMA A;  2FTD A;  3PW3 A;  3K9M A;  3MOR A;  3NHE A;  3O0U A;  1PPN A;  1TLO A;  2YJC A;  1Y08 A;  2CIO A;  2JQF R;  1U9Q X;  3K8U A;  4RY2 A;  5CVN B;  1AIM A;  4YYQ A;  1M6D A;  1PIP A;  3WXE A;  2R9N A;  2BDL A;  2GHU A;  3ZUA A;  1AU0 A;  1FH0 A;  1ME4 A;  2B1M A;  2PRE A;  4MSX A;  2XU3 A;  1PXV A;  1CPJ A;  2R9F A;  1ATK A;  4ZUX U;  2HH5 A;  2G8E A;  3KWB X;  1QOL A;  1O0E A;  4P6G A;  2HD5 A;  3RVW A;  3QT4 A;  3N3K A;  1GEC E;  3KX1 A;  3OVZ A;  2PBH A;  4AXL A;  1AU3 A;  2YJ2 A;  3F5V A;  3WXG A;  1CJL A;  3OF8 A;  4OEM A;  2R6N A;  7PCK A;  1VJV A;  2E02 A;  2YJ8 A;  4CDF B;  2OZ2 A;  3BC3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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