3PNRA

Structure of pbicp-c in complex with falcipain-2
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
240
structure length
240
Chain Sequence
MNYEEVIKKYRGEENFDHAAYDWRLHSGVTPVKDQKNCGSAWAFSSIGSVESQYAIRKNKLITLSEQELVDCSFKNYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNIDRCTEKYGIKNYLSVPDNKLKEALRFLGPISISVAVSDDFAFYKEGIFDGECGDQLNHAVMLVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFIPLIE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Plasmodium falciparum
molecule keywords Falcipain 2
total genus 65
structure length 240
sequence length 240
ec nomenclature
pdb deposition date 2010-11-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 3pnrA00
5JA7A 1U9VA 2FRAA 5J94A 1KFUL 1QMYA 4BPVA 3V6EA 1PADA 2WBFX 3IHPA 1KFXL 1F2BA 1EWPA 3F75A 4HWYA 3WXGA 5CVOB 1ATKA 3KKUA 1CTEA 3KFQA 4CZWA 1AU4A 1PE6A 2NQIA 3N4CA 3MHSA 3PDFA 2B1MA 2DC9A 3BPFA 1AYWA 4CDEB 1CVZA 1AIMA 1A6RA 2FT2A 2DC8A 3NHEA 1JQPA 2R9FA 1GMYA 2P0RA 4YYSA 6PADA 3CH2X 2DZYA 1U9WA 2GHUA 1EWMA 1FH0A 3KWZA 3P5UA 3ERVA 2DCCA 1K3BB 2AS8A 3S3RA 2Y6EA 2E03A 2YJ2A 4PP1A 2F1GA 1THEA 2AUXA 1STFE 2VHSA 4MZSA 3OF9A 4ZUXU 2P7UA 1BQIA 2DJFB 4PADA 3BPMA 1YK8A 1HUCB 2OULA 1KHPA 1YVBA 4YYUA 1CSBB 3OF8A 4YYQA 4I04A 3IOQA 5CVMA 3CBKA 1AYUA 2DC7A 3P5VA 2PBHA 5A24A 9PAPA 3AI8A 2B1NA 2C0YA 4MSXA 4AXLA 3RVVA 3ZUAA 1EWLA 4X6HA 1BY8A 4OELA 4K7CA 1CV8A 5PADA 5K16A 1BGOA 4CDDB 2E02A 3PBHA 2G7YA 4N8WA 4N79A 5EGWA 2Y5BA 2NQDB 1Y4HA 1SNKA 3HHAA 2GFOA 2E00A 1KXRA 1DF0A 2HH5A 1PXVA 2DC6A 1F2AA 4QRGA 2YJBA 3WXFA 2ATOA 2XU4A 1PPDA 5CHTA 3B79A 3USVA 3P5WA 1PIPA 2IPPB 4WA6A 4BS5A 3LFYA 4I05A 3K9MA 2O6XA 2YJ8A 3O1GA 1YT7A 1TL9A 1S4VA 3OISA 1MDWA 1EWOA 2HXZA 4YYVA 5F02A 1NB5A 2R9OA 4P6EA 2FYEA 2G8EA 2AU1A 3MHHA 2FQ9A 2PADA 3I3TA 4N4ZA 4BSQA 1CPJA 1QOLA 3WXEA 3IMAA 4FK5A 2DZZA 4W5CA 1ITOA 3N3GA 1AECA 1PPOA 1QDQA 1MEMA 4QBBA 2VHFA 3IUTA 4W4UA 4KLBA 3S3QA 4I07A 1BP4A 2AIMA 1AU2A 4W5BA 5CVNB 4PI3A 1CB5A 1M6DA 3PW3A 4FIPA 3BCNA 1DEUA 2HHNA 2PNSA 2G8JA 3M99A 4FJCA 3RVWA 1MIRA 2DJGB 2H7JA 2P86A 2PREA 3KX1A 1ME4A 1VSNA 4BQVA 3I06A 4YYWA 2ARYA 4Q8HA 2NQGA 5EF4A 4YYRA 3P5XA 1TU6A 3H7DA 3KSEA 3H8CA 1YALA 5CHVA 4YVAA 1AU0A 1MHWA 4OEMA 3F5VA 3H89A 2R9NA 1GLOA 1VJVA 3E1ZB 3CBJA 2XU5A 2NQAA 1ICFA 3GCBA 2DCAA 4XR7A 1QXPA 2E01A 3TNXA 3V6CA 2YJCA 2AYOA 1Q6KA 2DCDA 1U9XA 3HD3A 2BDLA 2JQGR 3KWBX 4BS6A 4X6IA 1ZCMA 2R9MA 4RY2A 1U5IA 4QH6A 3QJ3A 3O0UA 2FO5A 8PCHA 2XU1A 2FRQA 1GECE 4P6GA 1U9QX 4X6JA 1PPPA 2R9CA 3MTNA 1CQDA 4CDCB 3H8BA 2AVWA 2AUZA 3K8UA 2ACTA 2BDZA 3MORA 5JH3A 1Y08A 2G6DA 3IEJA 1PBHA 1O0EA 4YV8A 2OZ2A 1GCBA 3BWKA 3RVXA 2F7DA 1IWDA 4CDFB 1NQCA 2HD5A 4DMYA 2CIOA 3PNRA 3OVXA 3N3KA 1F29A 1MS6A 3OVZA 4Q8GA 1YK7A 3HWNA 2IBIA 3KW9A 1NB3A 1CS8A 3U8EA 1F2CA 1ME3A 1CJLA 2JQFR 4QRXA 1PPNA 4QRVA 3K24A 1EF7A 1SP4B 2FUDA 4XUIA 3IV2A 2AYNA 2FTDA 1POPA 2XU3A 1XKGA 3BC3A 1ZIVA 2CB5A 5FPWA 3BOWA 1PCIA 1AU3A 4MZOA 1NLJA 2YJ9A 4DMXA 1NL6A 7PCKA 4G54A 1MEGA 4AXMA 1NPZA 3DF0A 2OP3A 3QT4A 4PP2E 1KHQA 3QSDA 3LXSA 2DCBA 3H6SA 3D6SA 3CH3X 3C9EA 2R6NA 3HHIA 1X9YA 1AYVA 1TLOA
chains in the Genus database with same CATH superfamily
5JA7A 1U9VA 2FRAA 5J94A 1KFUL 1QMYA 4BPVA 3BBAA 3V6EA 1PADA 2WBFX 3IHPA 1KFXL 1F2BA 1EWPA 3F75A 4HWYA 3WXGA 5CVOB 1ATKA 3KKUA 1CTEA 3KFQA 4CZWA 4BOQA 1AU4A 2J7QA 1PE6A 2NQIA 3N4CA 3MHSA 3PDFA 4OVZB 2B1MA 2DC9A 3BPFA 1AYWA 4CDEB 1CVZA 1AIMA 1A6RA 2FT2A 2DC8A 3NHEA 1JQPA 2R9FA 1GMYA 2P0RA 4YYSA 6PADA 3PT2A 3CH2X 2DZYA 1U9WA 4GUAA 2GHUA 1EWMA 4BOZA 1FH0A 3KWZA 3P5UA 3ERVA 2DCCA 1K3BB 1UKFA 2AS8A 3S3RA 2Y6EA 2E03A 2YJ2A 4PP1A 4A5UA 2F1GA 1THEA 2AUXA 1STFE 2VHSA 4MZSA 3OF9A 4ZUXU 2P7UA 1BQIA 2DJFB 4PADA 2BU3A 3BPMA 3BB7A 1YK8A 1HUCB 2OULA 1KHPA 1YVBA 4YYUA 4REZA 1CSBB 3OF8A 4YYQA 4I04A 3IOQA 3PHWA 5CVMA 3CBKA 1AYUA 2DC7A 3P5VA 2PBHA 5A24A 9PAPA 3AI8A 2B1NA 2C0YA 4MSXA 4AXLA 2AGAA 3RVVA 3ZUAA 4RF1A 1EWLA 4X6HA 1BY8A 4OELA 4K7CA 3PHUA 4MI7A 1CV8A 5PADA 4RF0A 3MP2A 4D8IA 3PHXA 5K16A 1BGOA 4CDDB 2E02A 3PBHA 2G7YA 4N8WA 4N79A 4RKXA 5EGWA 2Y5BA 2NQDB 1Y4HA 1SNKA 3HHAA 2GFOA 2E00A 1KXRA 1DF0A 2HH5A 4XZXA 4BOPA 1PXVA 2DC6A 1F2AA 4QRGA 2YJBA 3WXFA 2ATOA 2XU4A 3MTVA 1PPDA 5CHTA 3B79A 3USVA 3P5WA 1PIPA 2IPPB 4WA6A 4BS5A 3LFYA 3MJ5A 4ZTBA 4I05A 3K9MA 1YZBA 2O6XA 2BTWA 2YJ8A 3O1GA 1YT7A 1TL9A 1S4VA 3OISA 1MDWA 1EWOA 2HXZA 4YYVA 5F02A 1NB5A 2R9OA 4P6EA 2FYEA 2G8EA 2AU1A 3MHHA 2FQ9A 2PADA 3I3TA 4N4ZA 4BSQA 1CPJA 1QOLA 3WXEA 3IMAA 4FK5A 2DZZA 4W5CA 1ITOA 5KO3A 3N3GA 1AECA 1PPOA 1QDQA 4D8BA 1MEMA 4QBBA 2VHFA 3IUTA 4W4UA 4KLBA 3S3QA 4I07A 1BP4A 2AIMA 1AU2A 4W5BA 5CVNB 4PI3A 1CB5A 1M6DA 3PW3A 2JRIA 4FIPA 3BCNA 1DEUA 2HHNA 2PNSA 2G8JA 3W31A 4OVZA 3M99A 4FJCA 1PVJA 4MM3B 3RVWA 1MIRA 2DJGB 2H7JA 2P86A 4HXDB 2PREA 3KX1A 1ME4A 1VSNA 4BQVA 3I06A 4YYWA 2ARYA 4Q8HA 2NQGA 5EF4A 4YYRA 3P5XA 1TU6A 3BY4A 5E6JA 3H7DA 3KSEA 3H8CA 1YALA 4P16A 5CHVA 4YVAA 3ZNHA 1AU0A 3TRKA 1MHWA 4OEMA 3F5VA 3H89A 2R9NA 1GLOA 1VJVA 3E1ZB 3CBJA 2XU5A 2HWKA 2NQAA 1ICFA 3GCBA 2DCAA 4XR7A 1QXPA 2E01A 3TNXA 3V6CA 4IP3A 2YJCA 2AYOA 1Q6KA 4BOSA 2DCDA 1U9XA 2Z84A 4D8EA 3HD3A 2BDLA 2JQGR 3KWBX 4BS6A 4X6IA 1ZCMA 2R9MA 4RY2A 1U5IA 4RNAA 4QH6A 3C0RA 2J7QC 3O65A 3QJ3A 3O0UA 2FO5A 5EZSA 3PRMA 4OW0A 8PCHA 2XU1A 2FRQA 1GECE 4P6GA 1U9QX 4X6JA 1PPPA 4WURA 2R9CA 1DKIA 3MTNA 1CQDA 4CDCB 3H8BA 2AVWA 4BOUA 2AUZA 3K8UA 3RNVA 2ACTA 2BDZA 3MORA 5JH3A 1Y08A 2G6DA 3IEJA 3PRPA 1PBHA 1O0EA 4YV8A 2OZ2A 1GCBA 3BWKA 3RVXA 2F7DA 1IWDA 4CDFB 1NQCA 2HD5A 4DMYA 3OQCA 2CIOA 3IFUA 3PNRA 2FE8A 3OVXA 3N3KA 1F29A 1MS6A 3OVZA 4Q8GA 1YK7A 3HWNA 2IBIA 3KW9A 1NB3A 5JZEA 1CS8A 3U8EA 3TMPA 1F2CA 1ME3A 1CJLA 2JQFR 4QRXA 1PPNA 4QRVA 3K24A 4IUMA 3PSEA 1EF7A 1SP4B 2FUDA 4XUIA 3IV2A 2AYNA 2FTDA 1POPA 2XU3A 1XKGA 3BC3A 4PT5A 1ZIVA 2CB5A 5FPWA 3BOWA 2BTWB 3E9SA 1PCIA 1AU3A 4MZOA 1NLJA 3W30A 2JTCA 2YJ9A 4DMXA 2UZJA 1NL6A 7PCKA 4G54A 1MEGA 4AXMA 1NPZA 3DF0A 2OP3A 3QT4A 4PP2E 2DOSA 1KHQA 3QSDA 3LXSA 2DCBA 5EZQA 3H6SA 3D6SA 3CH3X 3C9EA 2R6NA 3HHIA 4R3DA 1X9YA 1AYVA 1TLOA 3B21A 4M0WA
chains in the Genus database with same CATH topology
5JA7A 1U9VA 2FRAA 5J94A 1KFUL 1QMYA 4BPVA 3V6EA 1PADA 2WBFX 3IHPA 1KFXL 1F2BA 1EWPA 3F75A 4HWYA 3WXGA 5CVOB 1ATKA 3KKUA 1CTEA 3KFQA 4CZWA 1AU4A 1PE6A 2NQIA 3N4CA 3MHSA 4B55A 3PDFA 2B1MA 2DC9A 3BPFA 1AYWA 4CDEB 1CVZA 1AIMA 1A6RA 2FT2A 2DC8A 3NHEA 1JQPA 2R9FA 1GMYA 2P0RA 4YYSA 6PADA 3CH2X 2DZYA 1U9WA 2GHUA 1EWMA 1FH0A 3KWZA 3P5UA 3ERVA 2DCCA 1K3BB 1W6FA 2AS8A 3S3RA 2Y6EA 2E03A 2YJ2A 4PP1A 2F1GA 1THEA 2AUXA 1STFE 2VHSA 4MZSA 3OF9A 4ZUXU 2P7UA 1BQIA 2DJFB 4PADA 3BPMA 1YK8A 1HUCB 2OULA 1KHPA 1YVBA 4YYUA 1CSBB 3OF8A 4YYQA 4I04A 3IOQA 5CVMA 3CBKA 1AYUA 2DC7A 3P5VA 2PBHA 5A24A 9PAPA 3AI8A 2B1NA 2C0YA 4MSXA 4AXLA 3RVVA 3ZUAA 4C5PA 1EWLA 4X6HA 1BY8A 4OELA 4K7CA 3LTWA 1CV8A 5PADA 5K16A 1BGOA 4CDDB 2E02A 3PBHA 2G7YA 4N8WA 4N79A 5EGWA 2Y5BA 2NQDB 1Y4HA 1SNKA 3HHAA 2GFOA 2E00A 1KXRA 1DF0A 2HH5A 1PXVA 2DC6A 1F2AA 4QRGA 2YJBA 3WXFA 2ATOA 2XU4A 4GUZA 1PPDA 5CHTA 3B79A 3USVA 3P5WA 1PIPA 2IPPB 4WA6A 4BS5A 3LFYA 4BGFA 4I05A 3K9MA 2O6XA 2YJ8A 3O1GA 1YT7A 1TL9A 1S4VA 3OISA 1MDWA 1EWOA 2HXZA 4YYVA 5F02A 1NB5A 2R9OA 4P6EA 2FYEA 2G8EA 2AU1A 3MHHA 2FQ9A 2PADA 3I3TA 4N4ZA 4BSQA 1CPJA 1QOLA 3WXEA 3IMAA 4FK5A 2DZZA 4W5CA 1ITOA 3N3GA 2BSZA 1AECA 2VFCA 1PPOA 1QDQA 1MEMA 4QBBA 2VHFA 3IUTA 4W4UA 4KLBA 3S3QA 4I07A 1BP4A 2AIMA 1AU2A 4W5BA 5CVNB 4PI3A 1CB5A 1M6DA 3PW3A 4FIPA 3BCNA 1DEUA 2HHNA 2PNSA 2G8JA 3M99A 4FJCA 3RVWA 1MIRA 2DJGB 2H7JA 2P86A 2PREA 3KX1A 1ME4A 1VSNA 4BQVA 3I06A 4YYWA 1GX3A 2ARYA 4Q8HA 2NQGA 5EF4A 4YYRA 3P5XA 1TU6A 3H7DA 3KSEA 3H8CA 1YALA 5CHVA 4YVAA 1AU0A 1MHWA 4OEMA 3F5VA 1W5RA 3H89A 2R9NA 1GLOA 1VJVA 3E1ZB 3CBJA 2XU5A 2NQAA 1ICFA 3GCBA 2DCAA 4XR7A 1QXPA 2E01A 3TNXA 1E2TA 3V6CA 2YJCA 2AYOA 1Q6KA 2DCDA 1U9XA 3HD3A 2BDLA 2JQGR 3KWBX 4BS6A 4X6IA 1W4TA 1ZCMA 2R9MA 4RY2A 1U5IA 4QH6A 3QJ3A 3O0UA 2FO5A 8PCHA 2XU1A 2FRQA 1GECE 4P6GA 1U9QX 4X6JA 1PPPA 4NV7A 2R9CA 3MTNA 1CQDA 4CDCB 3H8BA 2AVWA 2AUZA 3K8UA 2ACTA 2BDZA 3MORA 5JH3A 1Y08A 2G6DA 3IEJA 1PBHA 1O0EA 4YV8A 2OZ2A 1GCBA 3BWKA 3RVXA 2F7DA 1IWDA 4CDFB 1NQCA 2HD5A 4DMYA 2CIOA 3PNRA 2VFBA 3OVXA 3N3KA 1F29A 1MS6A 3OVZA 4Q8GA 1YK7A 3HWNA 2IBIA 3D9WA 3KW9A 1NB3A 1CS8A 3U8EA 1F2CA 1ME3A 1CJLA 2JQFR 4QRXA 1PPNA 4QRVA 3K24A 1EF7A 1SP4B 2FUDA 4XUIA 3IV2A 2AYNA 2FTDA 1POPA 2XU3A 1XKGA 3BC3A 1ZIVA 2CB5A 4NV8A 5FPWA 3BOWA 1PCIA 1AU3A 4MZOA 1NLJA 2YJ9A 4DMXA 1NL6A 7PCKA 4G54A 1MEGA 4AXMA 1NPZA 3DF0A 2OP3A 3QT4A 4PP2E 1KHQA 3QSDA 3LXSA 2DCBA 3H6SA 3D6SA 3CH3X 3C9EA 2R6NA 3HHIA 1X9YA 1AYVA 1TLOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JA7 A;  1U9V A;  2FRA A;  5J94 A;  1KFU L;  1QMY A;  4BPV A;  3V6E A;  1PAD A;  2WBF X;  3IHP A;  1KFX L;  1F2B A;  1EWP A;  3F75 A;  4HWY A;  3WXG A;  5CVO B;  1ATK A;  3KKU A;  1CTE A;  3KFQ A;  4CZW A;  1AU4 A;  1PE6 A;  2NQI A;  3N4C A;  3MHS A;  3PDF A;  2B1M A;  2DC9 A;  3BPF A;  1AYW A;  4CDE B;  1CVZ A;  1AIM A;  1A6R A;  2FT2 A;  2DC8 A;  3NHE A;  1JQP A;  2R9F A;  1GMY A;  2P0R A;  4YYS A;  6PAD A;  3CH2 X;  2DZY A;  1U9W A;  2GHU A;  1EWM A;  1FH0 A;  3KWZ A;  3P5U A;  3ERV A;  2DCC A;  1K3B B;  2AS8 A;  3S3R A;  2Y6E A;  2E03 A;  2YJ2 A;  4PP1 A;  2F1G A;  1THE A;  2AUX A;  1STF E;  2VHS A;  4MZS A;  3OF9 A;  4ZUX U;  2P7U A;  1BQI A;  2DJF B;  4PAD A;  3BPM A;  1YK8 A;  1HUC B;  2OUL A;  1KHP A;  1YVB A;  4YYU A;  1CSB B;  3OF8 A;  4YYQ A;  4I04 A;  3IOQ A;  5CVM A;  3CBK A;  1AYU A;  2DC7 A;  3P5V A;  2PBH A;  5A24 A;  9PAP A;  3AI8 A;  2B1N A;  2C0Y A;  4MSX A;  4AXL A;  3RVV A;  3ZUA A;  1EWL A;  4X6H A;  1BY8 A;  4OEL A;  4K7C A;  1CV8 A;  5PAD A;  5K16 A;  1BGO A;  4CDD B;  2E02 A;  3PBH A;  2G7Y A;  4N8W A;  4N79 A;  5EGW A;  2Y5B A;  2NQD B;  1Y4H A;  1SNK A;  3HHA A;  2GFO A;  2E00 A;  1KXR A;  1DF0 A;  2HH5 A;  1PXV A;  2DC6 A;  1F2A A;  4QRG A;  2YJB A;  3WXF A;  2ATO A;  2XU4 A;  1PPD A;  5CHT A;  3B79 A;  3USV A;  3P5W A;  1PIP A;  2IPP B;  4WA6 A;  4BS5 A;  3LFY A;  4I05 A;  3K9M A;  2O6X A;  2YJ8 A;  3O1G A;  1YT7 A;  1TL9 A;  1S4V A;  3OIS A;  1MDW A;  1EWO A;  2HXZ A;  4YYV A;  5F02 A;  1NB5 A;  2R9O A;  4P6E A;  2FYE A;  2G8E A;  2AU1 A;  3MHH A;  2FQ9 A;  2PAD A;  3I3T A;  4N4Z A;  4BSQ A;  1CPJ A;  1QOL A;  3WXE A;  3IMA A;  4FK5 A;  2DZZ A;  4W5C A;  1ITO A;  3N3G A;  1AEC A;  1PPO A;  1QDQ A;  1MEM A;  4QBB A;  2VHF A;  3IUT A;  4W4U A;  4KLB A;  3S3Q A;  4I07 A;  1BP4 A;  2AIM A;  1AU2 A;  4W5B A;  5CVN B;  4PI3 A;  1CB5 A;  1M6D A;  3PW3 A;  4FIP A;  3BCN A;  1DEU A;  2HHN A;  2PNS A;  2G8J A;  3M99 A;  4FJC A;  3RVW A;  1MIR A;  2DJG B;  2H7J A;  2P86 A;  2PRE A;  3KX1 A;  1ME4 A;  1VSN A;  4BQV A;  3I06 A;  4YYW A;  2ARY A;  4Q8H A;  2NQG A;  5EF4 A;  4YYR A;  3P5X A;  1TU6 A;  3H7D A;  3KSE A;  3H8C A;  1YAL A;  5CHV A;  4YVA A;  1AU0 A;  1MHW A;  4OEM A;  3F5V A;  3H89 A;  2R9N A;  1GLO A;  1VJV A;  3E1Z B;  3CBJ A;  2XU5 A;  2NQA A;  1ICF A;  3GCB A;  2DCA A;  4XR7 A;  1QXP A;  2E01 A;  3TNX A;  3V6C A;  2YJC A;  2AYO A;  1Q6K A;  2DCD A;  1U9X A;  3HD3 A;  2BDL A;  2JQG R;  3KWB X;  4BS6 A;  4X6I A;  1ZCM A;  2R9M A;  4RY2 A;  1U5I A;  4QH6 A;  3QJ3 A;  3O0U A;  2FO5 A;  8PCH A;  2XU1 A;  2FRQ A;  1GEC E;  4P6G A;  1U9Q X;  4X6J A;  1PPP A;  2R9C A;  3MTN A;  1CQD A;  4CDC B;  3H8B A;  2AVW A;  2AUZ A;  3K8U A;  2ACT A;  2BDZ A;  3MOR A;  5JH3 A;  1Y08 A;  2G6D A;  3IEJ A;  1PBH A;  1O0E A;  4YV8 A;  2OZ2 A;  1GCB A;  3BWK A;  3RVX A;  2F7D A;  1IWD A;  4CDF B;  1NQC A;  2HD5 A;  4DMY A;  2CIO A;  3PNR A;  3OVX A;  3N3K A;  1F29 A;  1MS6 A;  3OVZ A;  4Q8G A;  1YK7 A;  3HWN A;  2IBI A;  3KW9 A;  1NB3 A;  1CS8 A;  3U8E A;  1F2C A;  1ME3 A;  1CJL A;  2JQF R;  4QRX A;  1PPN A;  4QRV A;  3K24 A;  1EF7 A;  1SP4 B;  2FUD A;  4XUI A;  3IV2 A;  2AYN A;  2FTD A;  1POP A;  2XU3 A;  1XKG A;  3BC3 A;  1ZIV A;  2CB5 A;  5FPW A;  3BOW A;  1PCI A;  1AU3 A;  4MZO A;  1NLJ A;  2YJ9 A;  4DMX A;  1NL6 A;  7PCK A;  4G54 A;  1MEG A;  4AXM A;  1NPZ A;  3DF0 A;  2OP3 A;  3QT4 A;  4PP2 E;  1KHQ A;  3QSD A;  3LXS A;  2DCB A;  3H6S A;  3D6S A;  3CH3 X;  3C9E A;  2R6N A;  3HHI A;  1X9Y A;  1AYV A;  1TLO A; 
#chains in the Genus database with same CATH topology
 5JA7 A;  1U9V A;  2FRA A;  5J94 A;  1KFU L;  1QMY A;  4BPV A;  3BBA A;  3V6E A;  1PAD A;  2WBF X;  3IHP A;  1KFX L;  1F2B A;  1EWP A;  3F75 A;  4HWY A;  3WXG A;  5CVO B;  1ATK A;  3KKU A;  1CTE A;  3KFQ A;  4CZW A;  4BOQ A;  1AU4 A;  2J7Q A;  1PE6 A;  2NQI A;  3N4C A;  3MHS A;  3PDF A;  4OVZ B;  2B1M A;  2DC9 A;  3BPF A;  1AYW A;  4CDE B;  1CVZ A;  1AIM A;  1A6R A;  2FT2 A;  2DC8 A;  3NHE A;  1JQP A;  2R9F A;  1GMY A;  2P0R A;  4YYS A;  6PAD A;  3PT2 A;  3CH2 X;  2DZY A;  1U9W A;  4GUA A;  2GHU A;  1EWM A;  4BOZ A;  1FH0 A;  3KWZ A;  3P5U A;  3ERV A;  2DCC A;  1K3B B;  1UKF A;  2AS8 A;  3S3R A;  2Y6E A;  2E03 A;  2YJ2 A;  4PP1 A;  4A5U A;  2F1G A;  1THE A;  2AUX A;  1STF E;  2VHS A;  4MZS A;  3OF9 A;  4ZUX U;  2P7U A;  1BQI A;  2DJF B;  4PAD A;  2BU3 A;  3BPM A;  3BB7 A;  1YK8 A;  1HUC B;  2OUL A;  1KHP A;  1YVB A;  4YYU A;  4REZ A;  1CSB B;  3OF8 A;  4YYQ A;  4I04 A;  3IOQ A;  3PHW A;  5CVM A;  3CBK A;  1AYU A;  2DC7 A;  3P5V A;  2PBH A;  5A24 A;  9PAP A;  3AI8 A;  2B1N A;  2C0Y A;  4MSX A;  4AXL A;  2AGA A;  3RVV A;  3ZUA A;  4RF1 A;  1EWL A;  4X6H A;  1BY8 A;  4OEL A;  4K7C A;  3PHU A;  4MI7 A;  1CV8 A;  5PAD A;  4RF0 A;  3MP2 A;  4D8I A;  3PHX A;  5K16 A;  1BGO A;  4CDD B;  2E02 A;  3PBH A;  2G7Y A;  4N8W A;  4N79 A;  4RKX A;  5EGW A;  2Y5B A;  2NQD B;  1Y4H A;  1SNK A;  3HHA A;  2GFO A;  2E00 A;  1KXR A;  1DF0 A;  2HH5 A;  4XZX A;  4BOP A;  1PXV A;  2DC6 A;  1F2A A;  4QRG A;  2YJB A;  3WXF A;  2ATO A;  2XU4 A;  3MTV A;  1PPD A;  5CHT A;  3B79 A;  3USV A;  3P5W A;  1PIP A;  2IPP B;  4WA6 A;  4BS5 A;  3LFY A;  3MJ5 A;  4ZTB A;  4I05 A;  3K9M A;  1YZB A;  2O6X A;  2BTW A;  2YJ8 A;  3O1G A;  1YT7 A;  1TL9 A;  1S4V A;  3OIS A;  1MDW A;  1EWO A;  2HXZ A;  4YYV A;  5F02 A;  1NB5 A;  2R9O A;  4P6E A;  2FYE A;  2G8E A;  2AU1 A;  3MHH A;  2FQ9 A;  2PAD A;  3I3T A;  4N4Z A;  4BSQ A;  1CPJ A;  1QOL A;  3WXE A;  3IMA A;  4FK5 A;  2DZZ A;  4W5C A;  1ITO A;  5KO3 A;  3N3G A;  1AEC A;  1PPO A;  1QDQ A;  4D8B A;  1MEM A;  4QBB A;  2VHF A;  3IUT A;  4W4U A;  4KLB A;  3S3Q A;  4I07 A;  1BP4 A;  2AIM A;  1AU2 A;  4W5B A;  5CVN B;  4PI3 A;  1CB5 A;  1M6D A;  3PW3 A;  2JRI A;  4FIP A;  3BCN A;  1DEU A;  2HHN A;  2PNS A;  2G8J A;  3W31 A;  4OVZ A;  3M99 A;  4FJC A;  1PVJ A;  4MM3 B;  3RVW A;  1MIR A;  2DJG B;  2H7J A;  2P86 A;  4HXD B;  2PRE A;  3KX1 A;  1ME4 A;  1VSN A;  4BQV A;  3I06 A;  4YYW A;  2ARY A;  4Q8H A;  2NQG A;  5EF4 A;  4YYR A;  3P5X A;  1TU6 A;  3BY4 A;  5E6J A;  3H7D A;  3KSE A;  3H8C A;  1YAL A;  4P16 A;  5CHV A;  4YVA A;  3ZNH A;  1AU0 A;  3TRK A;  1MHW A;  4OEM A;  3F5V A;  3H89 A;  2R9N A;  1GLO A;  1VJV A;  3E1Z B;  3CBJ A;  2XU5 A;  2HWK A;  2NQA A;  1ICF A;  3GCB A;  2DCA A;  4XR7 A;  1QXP A;  2E01 A;  3TNX A;  3V6C A;  4IP3 A;  2YJC A;  2AYO A;  1Q6K A;  4BOS A;  2DCD A;  1U9X A;  2Z84 A;  4D8E A;  3HD3 A;  2BDL A;  2JQG R;  3KWB X;  4BS6 A;  4X6I A;  1ZCM A;  2R9M A;  4RY2 A;  1U5I A;  4RNA A;  4QH6 A;  3C0R A;  2J7Q C;  3O65 A;  3QJ3 A;  3O0U A;  2FO5 A;  5EZS A;  3PRM A;  4OW0 A;  8PCH A;  2XU1 A;  2FRQ A;  1GEC E;  4P6G A;  1U9Q X;  4X6J A;  1PPP A;  4WUR A;  2R9C A;  1DKI A;  3MTN A;  1CQD A;  4CDC B;  3H8B A;  2AVW A;  4BOU A;  2AUZ A;  3K8U A;  3RNV A;  2ACT A;  2BDZ A;  3MOR A;  5JH3 A;  1Y08 A;  2G6D A;  3IEJ A;  3PRP A;  1PBH A;  1O0E A;  4YV8 A;  2OZ2 A;  1GCB A;  3BWK A;  3RVX A;  2F7D A;  1IWD A;  4CDF B;  1NQC A;  2HD5 A;  4DMY A;  3OQC A;  2CIO A;  3IFU A;  3PNR A;  2FE8 A;  3OVX A;  3N3K A;  1F29 A;  1MS6 A;  3OVZ A;  4Q8G A;  1YK7 A;  3HWN A;  2IBI A;  3KW9 A;  1NB3 A;  5JZE A;  1CS8 A;  3U8E A;  3TMP A;  1F2C A;  1ME3 A;  1CJL A;  2JQF R;  4QRX A;  1PPN A;  4QRV A;  3K24 A;  4IUM A;  3PSE A;  1EF7 A;  1SP4 B;  2FUD A;  4XUI A;  3IV2 A;  2AYN A;  2FTD A;  1POP A;  2XU3 A;  1XKG A;  3BC3 A;  4PT5 A;  1ZIV A;  2CB5 A;  5FPW A;  3BOW A;  2BTW B;  3E9S A;  1PCI A;  1AU3 A;  4MZO A;  1NLJ A;  3W30 A;  2JTC A;  2YJ9 A;  4DMX A;  2UZJ A;  1NL6 A;  7PCK A;  4G54 A;  1MEG A;  4AXM A;  1NPZ A;  3DF0 A;  2OP3 A;  3QT4 A;  4PP2 E;  2DOS A;  1KHQ A;  3QSD A;  3LXS A;  2DCB A;  5EZQ A;  3H6S A;  3D6S A;  3CH3 X;  3C9E A;  2R6N A;  3HHI A;  4R3D A;  1X9Y A;  1AYV A;  1TLO A;  3B21 A;  4M0W A; 
#chains in the Genus database with same CATH homology
 5JA7 A;  1U9V A;  2FRA A;  5J94 A;  1KFU L;  1QMY A;  4BPV A;  3V6E A;  1PAD A;  2WBF X;  3IHP A;  1KFX L;  1F2B A;  1EWP A;  3F75 A;  4HWY A;  3WXG A;  5CVO B;  1ATK A;  3KKU A;  1CTE A;  3KFQ A;  4CZW A;  1AU4 A;  1PE6 A;  2NQI A;  3N4C A;  3MHS A;  4B55 A;  3PDF A;  2B1M A;  2DC9 A;  3BPF A;  1AYW A;  4CDE B;  1CVZ A;  1AIM A;  1A6R A;  2FT2 A;  2DC8 A;  3NHE A;  1JQP A;  2R9F A;  1GMY A;  2P0R A;  4YYS A;  6PAD A;  3CH2 X;  2DZY A;  1U9W A;  2GHU A;  1EWM A;  1FH0 A;  3KWZ A;  3P5U A;  3ERV A;  2DCC A;  1K3B B;  1W6F A;  2AS8 A;  3S3R A;  2Y6E A;  2E03 A;  2YJ2 A;  4PP1 A;  2F1G A;  1THE A;  2AUX A;  1STF E;  2VHS A;  4MZS A;  3OF9 A;  4ZUX U;  2P7U A;  1BQI A;  2DJF B;  4PAD A;  3BPM A;  1YK8 A;  1HUC B;  2OUL A;  1KHP A;  1YVB A;  4YYU A;  1CSB B;  3OF8 A;  4YYQ A;  4I04 A;  3IOQ A;  5CVM A;  3CBK A;  1AYU A;  2DC7 A;  3P5V A;  2PBH A;  5A24 A;  9PAP A;  3AI8 A;  2B1N A;  2C0Y A;  4MSX A;  4AXL A;  3RVV A;  3ZUA A;  4C5P A;  1EWL A;  4X6H A;  1BY8 A;  4OEL A;  4K7C A;  3LTW A;  1CV8 A;  5PAD A;  5K16 A;  1BGO A;  4CDD B;  2E02 A;  3PBH A;  2G7Y A;  4N8W A;  4N79 A;  5EGW A;  2Y5B A;  2NQD B;  1Y4H A;  1SNK A;  3HHA A;  2GFO A;  2E00 A;  1KXR A;  1DF0 A;  2HH5 A;  1PXV A;  2DC6 A;  1F2A A;  4QRG A;  2YJB A;  3WXF A;  2ATO A;  2XU4 A;  4GUZ A;  1PPD A;  5CHT A;  3B79 A;  3USV A;  3P5W A;  1PIP A;  2IPP B;  4WA6 A;  4BS5 A;  3LFY A;  4BGF A;  4I05 A;  3K9M A;  2O6X A;  2YJ8 A;  3O1G A;  1YT7 A;  1TL9 A;  1S4V A;  3OIS A;  1MDW A;  1EWO A;  2HXZ A;  4YYV A;  5F02 A;  1NB5 A;  2R9O A;  4P6E A;  2FYE A;  2G8E A;  2AU1 A;  3MHH A;  2FQ9 A;  2PAD A;  3I3T A;  4N4Z A;  4BSQ A;  1CPJ A;  1QOL A;  3WXE A;  3IMA A;  4FK5 A;  2DZZ A;  4W5C A;  1ITO A;  3N3G A;  2BSZ A;  1AEC A;  2VFC A;  1PPO A;  1QDQ A;  1MEM A;  4QBB A;  2VHF A;  3IUT A;  4W4U A;  4KLB A;  3S3Q A;  4I07 A;  1BP4 A;  2AIM A;  1AU2 A;  4W5B A;  5CVN B;  4PI3 A;  1CB5 A;  1M6D A;  3PW3 A;  4FIP A;  3BCN A;  1DEU A;  2HHN A;  2PNS A;  2G8J A;  3M99 A;  4FJC A;  3RVW A;  1MIR A;  2DJG B;  2H7J A;  2P86 A;  2PRE A;  3KX1 A;  1ME4 A;  1VSN A;  4BQV A;  3I06 A;  4YYW A;  1GX3 A;  2ARY A;  4Q8H A;  2NQG A;  5EF4 A;  4YYR A;  3P5X A;  1TU6 A;  3H7D A;  3KSE A;  3H8C A;  1YAL A;  5CHV A;  4YVA A;  1AU0 A;  1MHW A;  4OEM A;  3F5V A;  1W5R A;  3H89 A;  2R9N A;  1GLO A;  1VJV A;  3E1Z B;  3CBJ A;  2XU5 A;  2NQA A;  1ICF A;  3GCB A;  2DCA A;  4XR7 A;  1QXP A;  2E01 A;  3TNX A;  1E2T A;  3V6C A;  2YJC A;  2AYO A;  1Q6K A;  2DCD A;  1U9X A;  3HD3 A;  2BDL A;  2JQG R;  3KWB X;  4BS6 A;  4X6I A;  1W4T A;  1ZCM A;  2R9M A;  4RY2 A;  1U5I A;  4QH6 A;  3QJ3 A;  3O0U A;  2FO5 A;  8PCH A;  2XU1 A;  2FRQ A;  1GEC E;  4P6G A;  1U9Q X;  4X6J A;  1PPP A;  4NV7 A;  2R9C A;  3MTN A;  1CQD A;  4CDC B;  3H8B A;  2AVW A;  2AUZ A;  3K8U A;  2ACT A;  2BDZ A;  3MOR A;  5JH3 A;  1Y08 A;  2G6D A;  3IEJ A;  1PBH A;  1O0E A;  4YV8 A;  2OZ2 A;  1GCB A;  3BWK A;  3RVX A;  2F7D A;  1IWD A;  4CDF B;  1NQC A;  2HD5 A;  4DMY A;  2CIO A;  3PNR A;  2VFB A;  3OVX A;  3N3K A;  1F29 A;  1MS6 A;  3OVZ A;  4Q8G A;  1YK7 A;  3HWN A;  2IBI A;  3D9W A;  3KW9 A;  1NB3 A;  1CS8 A;  3U8E A;  1F2C A;  1ME3 A;  1CJL A;  2JQF R;  4QRX A;  1PPN A;  4QRV A;  3K24 A;  1EF7 A;  1SP4 B;  2FUD A;  4XUI A;  3IV2 A;  2AYN A;  2FTD A;  1POP A;  2XU3 A;  1XKG A;  3BC3 A;  1ZIV A;  2CB5 A;  4NV8 A;  5FPW A;  3BOW A;  1PCI A;  1AU3 A;  4MZO A;  1NLJ A;  2YJ9 A;  4DMX A;  1NL6 A;  7PCK A;  4G54 A;  1MEG A;  4AXM A;  1NPZ A;  3DF0 A;  2OP3 A;  3QT4 A;  4PP2 E;  1KHQ A;  3QSD A;  3LXS A;  2DCB A;  3H6S A;  3D6S A;  3CH3 X;  3C9E A;  2R6N A;  3HHI A;  1X9Y A;  1AYV A;  1TLO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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