4CDEB

Human dpp1 in complex with 4-amino-n-((1s)-1-cyano-2-(4-(4- cyanophenyl)phenyl)ethyl)tetrahydropyran-4-carboxamide
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
161
structure length
161
Chain Sequence
HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHH
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN
total genus 46
structure length 161
sequence length 161
chains with identical sequence E
ec nomenclature ec 3.4.14.1: Dipeptidyl-peptidase I.
pdb deposition date 2013-10-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4cdeB01
1PE6A 3I06A 3DF0A 1VJVA 2VHFA 2R9FA 1QXPA 4Q8GA 3PW3A 1MEMA 2FYEA 1U9QX 2E03A 4X6JA 1CS8A 3N3GA 3GCBA 1CSBB 3P5UA 4OEMA 2DZZA 1YT7A 3MHHA 1AYWA 3MHSA 2JQFR 2E00A 4CDFB 2FRAA 3HD3A 3ERVA 4QBBA 3V6CA 1XKGA 1PBHA 1GLOA 1NQCA 3OVXA 2G8EA 3RVWA 2YJCA 3F75A 1NB3A 2ARYA 1EWPA 2P7UA 3MTNA 2DCAA 4PP2E 3S3QA 5CVNB 1BQIA 4YVAA 1X9YA 2R9OA 2G8JA 3MORA 1GCBA 2DC9A 3N4CA 5EGWA 4QRGA 2DZYA 2DC6A 4Q8HA 6PADA 2CIOA 2DC8A 2NQIA 4BQVA 3KWBX 1THEA 2FTDA 4ZUXU 1SP4B 1PPPA 2H7JA 1EF7A 2HXZA 3OF8A 3USVA 2HH5A 4N4ZA 3BPMA 3H8BA 1KXRA 1MS6A 3KKUA 3U8EA 5CVOB 2XU4A 5JH3A 2ACTA 1U9VA 3WXEA 2AYOA 2NQAA 2WBFX 1AECA 2OULA 3QJ3A 2BDZA 3K9MA 1EWLA 5CHTA 3V6EA 1NLJA 1S4VA 2DCBA 1QMYA 2F7DA 5CVMA 4N8WA 3C9EA 3PNRA 1Y4HA 2DCDA 5PADA 1CV8A 4YV8A 1AU3A 2FUDA 4XUIA 1EWOA 1PADA 2G7YA 4YYRA 3B79A 1U9XA 1MEGA 1ZCMA 4BPVA 1DEUA 2GHUA 2AU1A 1YK7A 2AIMA 4HWYA 1MHWA 3M99A 2DJGB 3CH2X 4RY2A 7PCKA 1CQDA 3HHAA 1KHPA 4YYSA 4FK5A 3HHIA 3O0UA 5A24A 1YVBA 1A6RA 1PXVA 2XU1A 2P0RA 2OP3A 1ZIVA 2FQ9A 4W5CA 3I3TA 4PADA 2NQGA 5J94A 2YJ8A 1STFE 4G54A 4XR7A 2Y5BA 2R9CA 3CH3X 2AS8A 2R9MA 2YJBA 1CB5A 3BOWA 2B1MA 4MZOA 4CZWA 4QRXA 2PNSA 1AU4A 1AU0A 3WXGA 2DJFB 3QT4A 4CDCB 4CDEB 4AXMA 1TLOA 2FO5A 1GECE 2FT2A 3RVVA 8PCHA 3LXSA 3ZUAA 4BSQA 1FH0A 1PCIA 2DCCA 1BGOA 5JA7A 1BY8A 3PDFA 1AU2A 3IEJA 1JQPA 2E02A 2AYNA 3KSEA 1ITOA 1QDQA 4PI3A 1VSNA 4P6EA 1KFUL 2OZ2A 5K16A 2P86A 1YALA 3AI8A 3P5VA 2IPPB 2B1NA 1ME4A 1F2AA 2F1GA 1SNKA 1AYVA 3OVZA 4QRVA 1CJLA 2AUXA 4DMYA 3KX1A 3IHPA 2VHSA 2CB5A 3H89A 3IMAA 4YYWA 1K3BB 1CPJA 4QH6A 1NL6A 2YJ9A 3IOQA 2Y6EA 1MDWA 2XU5A 9PAPA 4FJCA 3PBHA 1KHQA 3D6SA 1AYUA 4BS5A 3HWNA 5EF4A 5F02A 1MIRA 2PADA 2R6NA 4P6GA 4AXLA 1POPA 5CHVA 4YYUA 4W5BA 1HUCB 2HHNA 1NPZA 2YJ2A 1PPNA 2HD5A 3N3KA 3TNXA 2PREA 3BPFA 4MZSA 3BCNA 3IUTA 3WXFA 2DC7A 3O1GA 2JQGR 4N79A 1IWDA 2C0YA 3CBKA 3F5VA 4DMXA 3RVXA 4I04A 1KFXL 4W4UA 1Y08A 3OISA 3OF9A 4CDDB 1TU6A 2GFOA 4I07A 4WA6A 3H8CA 3CBJA 4OELA 3S3RA 2XU3A 1PPDA 4FIPA 2AVWA 3KWZA 1ICFA 4PP1A 1O0EA 1DF0A 3QSDA 2E01A 3BWKA 1F2BA 3K8UA 3P5WA 2O6XA 4K7CA 2ATOA 4KLBA 1F29A 2PBHA 1ATKA 1F2CA 1PIPA 3KW9A 1NB5A 2FRQA 2G6DA 1BP4A 3K24A 4YYQA 4X6HA 1U9WA 4I05A 1CVZA 1TL9A 3KFQA 3IV2A 1M6DA 1YK8A 5FPWA 3E1ZB 2R9NA 4BS6A 2IBIA 1GMYA 3H6SA 1EWMA 1CTEA 4YYVA 2AUZA 2NQDB 3P5XA 4X6IA 1QOLA 3H7DA 4MSXA 1AIMA 3NHEA 3BC3A 1Q6KA 1ME3A 2BDLA 1PPOA 3LFYA 1U5IA
chains in the Genus database with same CATH superfamily
1PE6A 3I06A 4BOQA 3DF0A 3PHXA 1VJVA 2VHFA 2R9FA 3MTVA 3BB7A 1QXPA 4Q8GA 3PW3A 1MEMA 2FYEA 1U9QX 2E03A 4X6JA 1DKIA 3BBAA 1PVJA 1CS8A 3N3GA 3GCBA 1CSBB 3PHUA 3P5UA 4OEMA 2DZZA 1YT7A 4ZTBA 3MHHA 1AYWA 3MHSA 2JQFR 2JTCA 2E00A 4CDFB 2FRAA 3HD3A 3ERVA 4QBBA 3V6CA 1XKGA 1PBHA 1GLOA 1NQCA 3OVXA 2G8EA 3RVWA 2YJCA 3F75A 4RF0A 4BOSA 1NB3A 2ARYA 1EWPA 2P7UA 3PRPA 3MTNA 2DCAA 4PP2E 2BU3A 3S3QA 5CVNB 1BQIA 4YVAA 1X9YA 4M0WA 2R9OA 2Z84A 2G8JA 3MORA 5EZQA 1GCBA 2DC9A 3N4CA 5EGWA 4QRGA 2DZYA 2DC6A 4Q8HA 6PADA 2CIOA 2DC8A 2NQIA 4BQVA 3KWBX 1THEA 2FTDA 4ZUXU 1SP4B 1PPPA 2H7JA 1EF7A 2HXZA 3OF8A 3USVA 2HH5A 4N4ZA 3BPMA 3H8BA 1KXRA 1MS6A 3KKUA 3U8EA 5CVOB 2XU4A 5JH3A 2ACTA 1U9VA 3WXEA 4OVZB 2AYOA 2NQAA 2WBFX 1AECA 2OULA 3QJ3A 2BDZA 3K9MA 1EWLA 4P16A 5CHTA 3V6EA 1NLJA 1S4VA 2DCBA 1QMYA 3E9SA 2F7DA 5CVMA 4N8WA 3C9EA 2BTWB 3PNRA 4D8EA 1Y4HA 3C0RA 2DCDA 5PADA 1CV8A 4YV8A 1AU3A 4PT5A 5JZEA 2FUDA 4XUIA 1EWOA 1PADA 3OQCA 2G7YA 2UZJA 4YYRA 3B79A 1U9XA 1MEGA 1ZCMA 4BPVA 1DEUA 2GHUA 2AU1A 1YK7A 2AIMA 5KO3A 1UKFA 4HWYA 4IP3A 1MHWA 3M99A 2DJGB 3CH2X 4RY2A 7PCKA 1CQDA 4HXDB 3HHAA 1KHPA 4YYSA 2AGAA 4FK5A 3HHIA 3O0UA 5A24A 1YVBA 1A6RA 1PXVA 2XU1A 4R3DA 4RNAA 2P0RA 2HWKA 2OP3A 1ZIVA 2FQ9A 4W5CA 3PSEA 3I3TA 4PADA 2NQGA 5J94A 2YJ8A 1STFE 4G54A 4XR7A 2Y5BA 2R9CA 3CH3X 2AS8A 2R9MA 2YJBA 1CB5A 3BOWA 2B1MA 4MZOA 4CZWA 4QRXA 4MI7A 2PNSA 1AU4A 1AU0A 3WXGA 2DJFB 5EZSA 3QT4A 4CDCB 4CDEB 4AXMA 1TLOA 2FO5A 1GECE 2DOSA 2FT2A 2J7QA 3RVVA 8PCHA 3LXSA 3ZUAA 4BSQA 1FH0A 1PCIA 2JRIA 2DCCA 1BGOA 5JA7A 1BY8A 3PDFA 2J7QC 1AU2A 3IEJA 1JQPA 2E02A 2AYNA 3KSEA 1ITOA 1QDQA 4PI3A 4IUMA 1VSNA 4P6EA 1KFUL 4BOUA 3TMPA 2OZ2A 5K16A 2P86A 1YALA 3AI8A 3P5VA 2IPPB 2B1NA 1ME4A 1F2AA 2F1GA 1SNKA 1AYVA 3OVZA 3MP2A 4QRVA 4A5UA 1CJLA 2AUXA 3PT2A 3W30A 4DMYA 3KX1A 3IHPA 2VHSA 3W31A 2CB5A 3H89A 3IMAA 3B21A 4YYWA 1K3BB 4BOZA 1CPJA 4QH6A 3PRMA 4RKXA 1NL6A 3O65A 4GUAA 2YJ9A 3IOQA 2Y6EA 1MDWA 1YZBA 2XU5A 9PAPA 4FJCA 3PBHA 1KHQA 3D6SA 1AYUA 2BTWA 4BS5A 3HWNA 5EF4A 5F02A 1MIRA 2PADA 3IFUA 2R6NA 4P6GA 5E6JA 4BOPA 4AXLA 1POPA 5CHVA 4D8BA 4YYUA 4W5BA 1HUCB 4WURA 2HHNA 1NPZA 2YJ2A 4RF1A 1PPNA 2HD5A 3N3KA 4OW0A 3TNXA 2PREA 3BPFA 4MZSA 3BCNA 3IUTA 3WXFA 2DC7A 3O1GA 2JQGR 4N79A 1IWDA 4MM3B 2C0YA 3PHWA 3CBKA 3F5VA 4DMXA 3RVXA 4I04A 1KFXL 4W4UA 1Y08A 3OISA 3OF9A 4CDDB 1TU6A 2GFOA 4I07A 4WA6A 3H8CA 3CBJA 4OELA 3S3RA 2XU3A 1PPDA 4FIPA 2AVWA 3KWZA 1ICFA 4PP1A 1O0EA 1DF0A 3QSDA 4D8IA 2E01A 3BWKA 1F2BA 3K8UA 3ZNHA 3P5WA 2O6XA 4K7CA 3TRKA 2ATOA 4KLBA 1F29A 2PBHA 1ATKA 1F2CA 1PIPA 3KW9A 1NB5A 2FRQA 2G6DA 1BP4A 3K24A 4YYQA 4X6HA 3RNVA 1U9WA 4I05A 4REZA 2FE8A 1CVZA 3MJ5A 1TL9A 3KFQA 3IV2A 1M6DA 1YK8A 5FPWA 3E1ZB 2R9NA 4BS6A 2IBIA 1GMYA 3H6SA 1EWMA 1CTEA 4YYVA 2AUZA 2NQDB 3P5XA 4X6IA 1QOLA 3H7DA 4MSXA 1AIMA 3NHEA 3BC3A 1Q6KA 1ME3A 2BDLA 1PPOA 3LFYA 4XZXA 4OVZA 1U5IA 3BY4A
chains in the Genus database with same CATH topology
1PE6A 3I06A 3DF0A 4NV8A 1VJVA 2VHFA 2R9FA 1W4TA 1QXPA 4Q8GA 3PW3A 1MEMA 2FYEA 1U9QX 2E03A 4X6JA 1CS8A 3N3GA 3GCBA 1CSBB 3P5UA 4OEMA 2DZZA 1YT7A 3MHHA 1AYWA 3MHSA 2JQFR 2E00A 4CDFB 2FRAA 3HD3A 3ERVA 4QBBA 3V6CA 1XKGA 1PBHA 1GLOA 1NQCA 3OVXA 2G8EA 3RVWA 2YJCA 3F75A 1NB3A 2ARYA 1EWPA 2P7UA 3MTNA 2DCAA 4PP2E 2VFCA 5CVNB 1BQIA 3S3QA 4YVAA 1X9YA 2R9OA 2G8JA 3MORA 1GCBA 2DC9A 3N4CA 5EGWA 4QRGA 2DZYA 2DC6A 4Q8HA 6PADA 2CIOA 2DC8A 2NQIA 4BQVA 3KWBX 1THEA 1GX3A 1W6FA 2FTDA 4ZUXU 1SP4B 1PPPA 2H7JA 1EF7A 2HXZA 3OF8A 3USVA 4N4ZA 2HH5A 3BPMA 3D9WA 3H8BA 1KXRA 1W5RA 1MS6A 3KKUA 3U8EA 5CVOB 2XU4A 5JH3A 2ACTA 1U9VA 3WXEA 3LTWA 2AYOA 2NQAA 2WBFX 1AECA 2OULA 3QJ3A 2BDZA 3K9MA 1EWLA 5CHTA 3V6EA 1NLJA 1S4VA 2DCBA 1QMYA 2F7DA 4BGFA 5CVMA 4N8WA 3C9EA 3PNRA 1Y4HA 2DCDA 5PADA 1CV8A 4YV8A 1AU3A 2FUDA 4XUIA 1EWOA 1PADA 2G7YA 4YYRA 3B79A 1U9XA 1MEGA 1ZCMA 4BPVA 1DEUA 2GHUA 2AU1A 1YK7A 2AIMA 4HWYA 1MHWA 3M99A 2DJGB 3CH2X 4RY2A 7PCKA 1CQDA 3HHAA 1KHPA 4YYSA 4FK5A 3HHIA 3O0UA 5A24A 1YVBA 1A6RA 1PXVA 2XU1A 2VFBA 2P0RA 2OP3A 1ZIVA 2FQ9A 4W5CA 3I3TA 4PADA 2NQGA 5J94A 2YJ8A 1STFE 4G54A 4XR7A 2Y5BA 2R9CA 4GUZA 3CH3X 2AS8A 2R9MA 2YJBA 1CB5A 3BOWA 2B1MA 4MZOA 4CZWA 4QRXA 2PNSA 1AU4A 1AU0A 3WXGA 2DJFB 3QT4A 4CDCB 4CDEB 4AXMA 1TLOA 2FO5A 1GECE 2FT2A 3RVVA 8PCHA 3LXSA 3ZUAA 4NV7A 4C5PA 4BSQA 1FH0A 1PCIA 2DCCA 1BGOA 5JA7A 1BY8A 3PDFA 1AU2A 3IEJA 1JQPA 2E02A 2AYNA 3KSEA 1ITOA 1QDQA 4PI3A 1VSNA 4P6EA 1KFUL 4B55A 2OZ2A 5K16A 2P86A 1YALA 3AI8A 3P5VA 2IPPB 2B1NA 1ME4A 1F2AA 2F1GA 1SNKA 1AYVA 3OVZA 4QRVA 1CJLA 2AUXA 4DMYA 3KX1A 3IHPA 2VHSA 2CB5A 3H89A 3IMAA 4YYWA 1K3BB 1CPJA 4QH6A 1NL6A 2YJ9A 3IOQA 2Y6EA 1MDWA 2XU5A 9PAPA 4FJCA 3PBHA 1KHQA 3D6SA 1AYUA 4BS5A 3HWNA 5EF4A 5F02A 1MIRA 2PADA 2R6NA 4P6GA 4AXLA 1POPA 5CHVA 4YYUA 1E2TA 4W5BA 1HUCB 2HHNA 1NPZA 2YJ2A 1PPNA 2HD5A 3N3KA 3TNXA 2PREA 3BPFA 4MZSA 3BCNA 3IUTA 3WXFA 2DC7A 3O1GA 2JQGR 4N79A 1IWDA 2C0YA 3CBKA 3F5VA 4DMXA 3RVXA 4I04A 1KFXL 4W4UA 1Y08A 3OISA 3OF9A 4CDDB 1TU6A 2GFOA 4I07A 4WA6A 3H8CA 3CBJA 4OELA 3S3RA 2XU3A 1PPDA 4FIPA 2AVWA 3KWZA 1ICFA 4PP1A 1O0EA 2BSZA 1DF0A 3QSDA 2E01A 3BWKA 1F2BA 3K8UA 3P5WA 2O6XA 4K7CA 2ATOA 4KLBA 1F29A 2PBHA 1ATKA 1F2CA 1PIPA 3KW9A 1NB5A 2FRQA 2G6DA 1BP4A 3K24A 4YYQA 4X6HA 1U9WA 4I05A 1CVZA 1TL9A 3KFQA 3IV2A 1M6DA 1YK8A 5FPWA 3E1ZB 2R9NA 4BS6A 2IBIA 1GMYA 3H6SA 1EWMA 1CTEA 4YYVA 2AUZA 2NQDB 3P5XA 4X6IA 1QOLA 3H7DA 4MSXA 1AIMA 3NHEA 3BC3A 1Q6KA 1ME3A 2BDLA 1PPOA 3LFYA 1U5IA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PE6 A;  3I06 A;  3DF0 A;  1VJV A;  2VHF A;  2R9F A;  1QXP A;  4Q8G A;  3PW3 A;  1MEM A;  2FYE A;  1U9Q X;  2E03 A;  4X6J A;  1CS8 A;  3N3G A;  3GCB A;  1CSB B;  3P5U A;  4OEM A;  2DZZ A;  1YT7 A;  3MHH A;  1AYW A;  3MHS A;  2JQF R;  2E00 A;  4CDF B;  2FRA A;  3HD3 A;  3ERV A;  4QBB A;  3V6C A;  1XKG A;  1PBH A;  1GLO A;  1NQC A;  3OVX A;  2G8E A;  3RVW A;  2YJC A;  3F75 A;  1NB3 A;  2ARY A;  1EWP A;  2P7U A;  3MTN A;  2DCA A;  4PP2 E;  3S3Q A;  5CVN B;  1BQI A;  4YVA A;  1X9Y A;  2R9O A;  2G8J A;  3MOR A;  1GCB A;  2DC9 A;  3N4C A;  5EGW A;  4QRG A;  2DZY A;  2DC6 A;  4Q8H A;  6PAD A;  2CIO A;  2DC8 A;  2NQI A;  4BQV A;  3KWB X;  1THE A;  2FTD A;  4ZUX U;  1SP4 B;  1PPP A;  2H7J A;  1EF7 A;  2HXZ A;  3OF8 A;  3USV A;  2HH5 A;  4N4Z A;  3BPM A;  3H8B A;  1KXR A;  1MS6 A;  3KKU A;  3U8E A;  5CVO B;  2XU4 A;  5JH3 A;  2ACT A;  1U9V A;  3WXE A;  2AYO A;  2NQA A;  2WBF X;  1AEC A;  2OUL A;  3QJ3 A;  2BDZ A;  3K9M A;  1EWL A;  5CHT A;  3V6E A;  1NLJ A;  1S4V A;  2DCB A;  1QMY A;  2F7D A;  5CVM A;  4N8W A;  3C9E A;  3PNR A;  1Y4H A;  2DCD A;  5PAD A;  1CV8 A;  4YV8 A;  1AU3 A;  2FUD A;  4XUI A;  1EWO A;  1PAD A;  2G7Y A;  4YYR A;  3B79 A;  1U9X A;  1MEG A;  1ZCM A;  4BPV A;  1DEU A;  2GHU A;  2AU1 A;  1YK7 A;  2AIM A;  4HWY A;  1MHW A;  3M99 A;  2DJG B;  3CH2 X;  4RY2 A;  7PCK A;  1CQD A;  3HHA A;  1KHP A;  4YYS A;  4FK5 A;  3HHI A;  3O0U A;  5A24 A;  1YVB A;  1A6R A;  1PXV A;  2XU1 A;  2P0R A;  2OP3 A;  1ZIV A;  2FQ9 A;  4W5C A;  3I3T A;  4PAD A;  2NQG A;  5J94 A;  2YJ8 A;  1STF E;  4G54 A;  4XR7 A;  2Y5B A;  2R9C A;  3CH3 X;  2AS8 A;  2R9M A;  2YJB A;  1CB5 A;  3BOW A;  2B1M A;  4MZO A;  4CZW A;  4QRX A;  2PNS A;  1AU4 A;  1AU0 A;  3WXG A;  2DJF B;  3QT4 A;  4CDC B;  4CDE B;  4AXM A;  1TLO A;  2FO5 A;  1GEC E;  2FT2 A;  3RVV A;  8PCH A;  3LXS A;  3ZUA A;  4BSQ A;  1FH0 A;  1PCI A;  2DCC A;  1BGO A;  5JA7 A;  1BY8 A;  3PDF A;  1AU2 A;  3IEJ A;  1JQP A;  2E02 A;  2AYN A;  3KSE A;  1ITO A;  1QDQ A;  4PI3 A;  1VSN A;  4P6E A;  1KFU L;  2OZ2 A;  5K16 A;  2P86 A;  1YAL A;  3AI8 A;  3P5V A;  2IPP B;  2B1N A;  1ME4 A;  1F2A A;  2F1G A;  1SNK A;  1AYV A;  3OVZ A;  4QRV A;  1CJL A;  2AUX A;  4DMY A;  3KX1 A;  3IHP A;  2VHS A;  2CB5 A;  3H89 A;  3IMA A;  4YYW A;  1K3B B;  1CPJ A;  4QH6 A;  1NL6 A;  2YJ9 A;  3IOQ A;  2Y6E A;  1MDW A;  2XU5 A;  9PAP A;  4FJC A;  3PBH A;  1KHQ A;  3D6S A;  1AYU A;  4BS5 A;  3HWN A;  5EF4 A;  5F02 A;  1MIR A;  2PAD A;  2R6N A;  4P6G A;  4AXL A;  1POP A;  5CHV A;  4YYU A;  4W5B A;  1HUC B;  2HHN A;  1NPZ A;  2YJ2 A;  1PPN A;  2HD5 A;  3N3K A;  3TNX A;  2PRE A;  3BPF A;  4MZS A;  3BCN A;  3IUT A;  3WXF A;  2DC7 A;  3O1G A;  2JQG R;  4N79 A;  1IWD A;  2C0Y A;  3CBK A;  3F5V A;  4DMX A;  3RVX A;  4I04 A;  1KFX L;  4W4U A;  1Y08 A;  3OIS A;  3OF9 A;  4CDD B;  1TU6 A;  2GFO A;  4I07 A;  4WA6 A;  3H8C A;  3CBJ A;  4OEL A;  3S3R A;  2XU3 A;  1PPD A;  4FIP A;  2AVW A;  3KWZ A;  1ICF A;  4PP1 A;  1O0E A;  1DF0 A;  3QSD A;  2E01 A;  3BWK A;  1F2B A;  3K8U A;  3P5W A;  2O6X A;  4K7C A;  2ATO A;  4KLB A;  1F29 A;  2PBH A;  1ATK A;  1F2C A;  1PIP A;  3KW9 A;  1NB5 A;  2FRQ A;  2G6D A;  1BP4 A;  3K24 A;  4YYQ A;  4X6H A;  1U9W A;  4I05 A;  1CVZ A;  1TL9 A;  3KFQ A;  3IV2 A;  1M6D A;  1YK8 A;  5FPW A;  3E1Z B;  2R9N A;  4BS6 A;  2IBI A;  1GMY A;  3H6S A;  1EWM A;  1CTE A;  4YYV A;  2AUZ A;  2NQD B;  3P5X A;  4X6I A;  1QOL A;  3H7D A;  4MSX A;  1AIM A;  3NHE A;  3BC3 A;  1Q6K A;  1ME3 A;  2BDL A;  1PPO A;  3LFY A;  1U5I A; 
#chains in the Genus database with same CATH topology
 1PE6 A;  3I06 A;  4BOQ A;  3DF0 A;  3PHX A;  1VJV A;  2VHF A;  2R9F A;  3MTV A;  3BB7 A;  1QXP A;  4Q8G A;  3PW3 A;  1MEM A;  2FYE A;  1U9Q X;  2E03 A;  4X6J A;  1DKI A;  3BBA A;  1PVJ A;  1CS8 A;  3N3G A;  3GCB A;  1CSB B;  3PHU A;  3P5U A;  4OEM A;  2DZZ A;  1YT7 A;  4ZTB A;  3MHH A;  1AYW A;  3MHS A;  2JQF R;  2JTC A;  2E00 A;  4CDF B;  2FRA A;  3HD3 A;  3ERV A;  4QBB A;  3V6C A;  1XKG A;  1PBH A;  1GLO A;  1NQC A;  3OVX A;  2G8E A;  3RVW A;  2YJC A;  3F75 A;  4RF0 A;  4BOS A;  1NB3 A;  2ARY A;  1EWP A;  2P7U A;  3PRP A;  3MTN A;  2DCA A;  4PP2 E;  2BU3 A;  3S3Q A;  5CVN B;  1BQI A;  4YVA A;  1X9Y A;  4M0W A;  2R9O A;  2Z84 A;  2G8J A;  3MOR A;  5EZQ A;  1GCB A;  2DC9 A;  3N4C A;  5EGW A;  4QRG A;  2DZY A;  2DC6 A;  4Q8H A;  6PAD A;  2CIO A;  2DC8 A;  2NQI A;  4BQV A;  3KWB X;  1THE A;  2FTD A;  4ZUX U;  1SP4 B;  1PPP A;  2H7J A;  1EF7 A;  2HXZ A;  3OF8 A;  3USV A;  2HH5 A;  4N4Z A;  3BPM A;  3H8B A;  1KXR A;  1MS6 A;  3KKU A;  3U8E A;  5CVO B;  2XU4 A;  5JH3 A;  2ACT A;  1U9V A;  3WXE A;  4OVZ B;  2AYO A;  2NQA A;  2WBF X;  1AEC A;  2OUL A;  3QJ3 A;  2BDZ A;  3K9M A;  1EWL A;  4P16 A;  5CHT A;  3V6E A;  1NLJ A;  1S4V A;  2DCB A;  1QMY A;  3E9S A;  2F7D A;  5CVM A;  4N8W A;  3C9E A;  2BTW B;  3PNR A;  4D8E A;  1Y4H A;  3C0R A;  2DCD A;  5PAD A;  1CV8 A;  4YV8 A;  1AU3 A;  4PT5 A;  5JZE A;  2FUD A;  4XUI A;  1EWO A;  1PAD A;  3OQC A;  2G7Y A;  2UZJ A;  4YYR A;  3B79 A;  1U9X A;  1MEG A;  1ZCM A;  4BPV A;  1DEU A;  2GHU A;  2AU1 A;  1YK7 A;  2AIM A;  5KO3 A;  1UKF A;  4HWY A;  4IP3 A;  1MHW A;  3M99 A;  2DJG B;  3CH2 X;  4RY2 A;  7PCK A;  1CQD A;  4HXD B;  3HHA A;  1KHP A;  4YYS A;  2AGA A;  4FK5 A;  3HHI A;  3O0U A;  5A24 A;  1YVB A;  1A6R A;  1PXV A;  2XU1 A;  4R3D A;  4RNA A;  2P0R A;  2HWK A;  2OP3 A;  1ZIV A;  2FQ9 A;  4W5C A;  3PSE A;  3I3T A;  4PAD A;  2NQG A;  5J94 A;  2YJ8 A;  1STF E;  4G54 A;  4XR7 A;  2Y5B A;  2R9C A;  3CH3 X;  2AS8 A;  2R9M A;  2YJB A;  1CB5 A;  3BOW A;  2B1M A;  4MZO A;  4CZW A;  4QRX A;  4MI7 A;  2PNS A;  1AU4 A;  1AU0 A;  3WXG A;  2DJF B;  5EZS A;  3QT4 A;  4CDC B;  4CDE B;  4AXM A;  1TLO A;  2FO5 A;  1GEC E;  2DOS A;  2FT2 A;  2J7Q A;  3RVV A;  8PCH A;  3LXS A;  3ZUA A;  4BSQ A;  1FH0 A;  1PCI A;  2JRI A;  2DCC A;  1BGO A;  5JA7 A;  1BY8 A;  3PDF A;  2J7Q C;  1AU2 A;  3IEJ A;  1JQP A;  2E02 A;  2AYN A;  3KSE A;  1ITO A;  1QDQ A;  4PI3 A;  4IUM A;  1VSN A;  4P6E A;  1KFU L;  4BOU A;  3TMP A;  2OZ2 A;  5K16 A;  2P86 A;  1YAL A;  3AI8 A;  3P5V A;  2IPP B;  2B1N A;  1ME4 A;  1F2A A;  2F1G A;  1SNK A;  1AYV A;  3OVZ A;  3MP2 A;  4QRV A;  4A5U A;  1CJL A;  2AUX A;  3PT2 A;  3W30 A;  4DMY A;  3KX1 A;  3IHP A;  2VHS A;  3W31 A;  2CB5 A;  3H89 A;  3IMA A;  3B21 A;  4YYW A;  1K3B B;  4BOZ A;  1CPJ A;  4QH6 A;  3PRM A;  4RKX A;  1NL6 A;  3O65 A;  4GUA A;  2YJ9 A;  3IOQ A;  2Y6E A;  1MDW A;  1YZB A;  2XU5 A;  9PAP A;  4FJC A;  3PBH A;  1KHQ A;  3D6S A;  1AYU A;  2BTW A;  4BS5 A;  3HWN A;  5EF4 A;  5F02 A;  1MIR A;  2PAD A;  3IFU A;  2R6N A;  4P6G A;  5E6J A;  4BOP A;  4AXL A;  1POP A;  5CHV A;  4D8B A;  4YYU A;  4W5B A;  1HUC B;  4WUR A;  2HHN A;  1NPZ A;  2YJ2 A;  4RF1 A;  1PPN A;  2HD5 A;  3N3K A;  4OW0 A;  3TNX A;  2PRE A;  3BPF A;  4MZS A;  3BCN A;  3IUT A;  3WXF A;  2DC7 A;  3O1G A;  2JQG R;  4N79 A;  1IWD A;  4MM3 B;  2C0Y A;  3PHW A;  3CBK A;  3F5V A;  4DMX A;  3RVX A;  4I04 A;  1KFX L;  4W4U A;  1Y08 A;  3OIS A;  3OF9 A;  4CDD B;  1TU6 A;  2GFO A;  4I07 A;  4WA6 A;  3H8C A;  3CBJ A;  4OEL A;  3S3R A;  2XU3 A;  1PPD A;  4FIP A;  2AVW A;  3KWZ A;  1ICF A;  4PP1 A;  1O0E A;  1DF0 A;  3QSD A;  4D8I A;  2E01 A;  3BWK A;  1F2B A;  3K8U A;  3ZNH A;  3P5W A;  2O6X A;  4K7C A;  3TRK A;  2ATO A;  4KLB A;  1F29 A;  2PBH A;  1ATK A;  1F2C A;  1PIP A;  3KW9 A;  1NB5 A;  2FRQ A;  2G6D A;  1BP4 A;  3K24 A;  4YYQ A;  4X6H A;  3RNV A;  1U9W A;  4I05 A;  4REZ A;  2FE8 A;  1CVZ A;  3MJ5 A;  1TL9 A;  3KFQ A;  3IV2 A;  1M6D A;  1YK8 A;  5FPW A;  3E1Z B;  2R9N A;  4BS6 A;  2IBI A;  1GMY A;  3H6S A;  1EWM A;  1CTE A;  4YYV A;  2AUZ A;  2NQD B;  3P5X A;  4X6I A;  1QOL A;  3H7D A;  4MSX A;  1AIM A;  3NHE A;  3BC3 A;  1Q6K A;  1ME3 A;  2BDL A;  1PPO A;  3LFY A;  4XZX A;  4OVZ A;  1U5I A;  3BY4 A; 
#chains in the Genus database with same CATH homology
 1PE6 A;  3I06 A;  3DF0 A;  4NV8 A;  1VJV A;  2VHF A;  2R9F A;  1W4T A;  1QXP A;  4Q8G A;  3PW3 A;  1MEM A;  2FYE A;  1U9Q X;  2E03 A;  4X6J A;  1CS8 A;  3N3G A;  3GCB A;  1CSB B;  3P5U A;  4OEM A;  2DZZ A;  1YT7 A;  3MHH A;  1AYW A;  3MHS A;  2JQF R;  2E00 A;  4CDF B;  2FRA A;  3HD3 A;  3ERV A;  4QBB A;  3V6C A;  1XKG A;  1PBH A;  1GLO A;  1NQC A;  3OVX A;  2G8E A;  3RVW A;  2YJC A;  3F75 A;  1NB3 A;  2ARY A;  1EWP A;  2P7U A;  3MTN A;  2DCA A;  4PP2 E;  2VFC A;  5CVN B;  1BQI A;  3S3Q A;  4YVA A;  1X9Y A;  2R9O A;  2G8J A;  3MOR A;  1GCB A;  2DC9 A;  3N4C A;  5EGW A;  4QRG A;  2DZY A;  2DC6 A;  4Q8H A;  6PAD A;  2CIO A;  2DC8 A;  2NQI A;  4BQV A;  3KWB X;  1THE A;  1GX3 A;  1W6F A;  2FTD A;  4ZUX U;  1SP4 B;  1PPP A;  2H7J A;  1EF7 A;  2HXZ A;  3OF8 A;  3USV A;  4N4Z A;  2HH5 A;  3BPM A;  3D9W A;  3H8B A;  1KXR A;  1W5R A;  1MS6 A;  3KKU A;  3U8E A;  5CVO B;  2XU4 A;  5JH3 A;  2ACT A;  1U9V A;  3WXE A;  3LTW A;  2AYO A;  2NQA A;  2WBF X;  1AEC A;  2OUL A;  3QJ3 A;  2BDZ A;  3K9M A;  1EWL A;  5CHT A;  3V6E A;  1NLJ A;  1S4V A;  2DCB A;  1QMY A;  2F7D A;  4BGF A;  5CVM A;  4N8W A;  3C9E A;  3PNR A;  1Y4H A;  2DCD A;  5PAD A;  1CV8 A;  4YV8 A;  1AU3 A;  2FUD A;  4XUI A;  1EWO A;  1PAD A;  2G7Y A;  4YYR A;  3B79 A;  1U9X A;  1MEG A;  1ZCM A;  4BPV A;  1DEU A;  2GHU A;  2AU1 A;  1YK7 A;  2AIM A;  4HWY A;  1MHW A;  3M99 A;  2DJG B;  3CH2 X;  4RY2 A;  7PCK A;  1CQD A;  3HHA A;  1KHP A;  4YYS A;  4FK5 A;  3HHI A;  3O0U A;  5A24 A;  1YVB A;  1A6R A;  1PXV A;  2XU1 A;  2VFB A;  2P0R A;  2OP3 A;  1ZIV A;  2FQ9 A;  4W5C A;  3I3T A;  4PAD A;  2NQG A;  5J94 A;  2YJ8 A;  1STF E;  4G54 A;  4XR7 A;  2Y5B A;  2R9C A;  4GUZ A;  3CH3 X;  2AS8 A;  2R9M A;  2YJB A;  1CB5 A;  3BOW A;  2B1M A;  4MZO A;  4CZW A;  4QRX A;  2PNS A;  1AU4 A;  1AU0 A;  3WXG A;  2DJF B;  3QT4 A;  4CDC B;  4CDE B;  4AXM A;  1TLO A;  2FO5 A;  1GEC E;  2FT2 A;  3RVV A;  8PCH A;  3LXS A;  3ZUA A;  4NV7 A;  4C5P A;  4BSQ A;  1FH0 A;  1PCI A;  2DCC A;  1BGO A;  5JA7 A;  1BY8 A;  3PDF A;  1AU2 A;  3IEJ A;  1JQP A;  2E02 A;  2AYN A;  3KSE A;  1ITO A;  1QDQ A;  4PI3 A;  1VSN A;  4P6E A;  1KFU L;  4B55 A;  2OZ2 A;  5K16 A;  2P86 A;  1YAL A;  3AI8 A;  3P5V A;  2IPP B;  2B1N A;  1ME4 A;  1F2A A;  2F1G A;  1SNK A;  1AYV A;  3OVZ A;  4QRV A;  1CJL A;  2AUX A;  4DMY A;  3KX1 A;  3IHP A;  2VHS A;  2CB5 A;  3H89 A;  3IMA A;  4YYW A;  1K3B B;  1CPJ A;  4QH6 A;  1NL6 A;  2YJ9 A;  3IOQ A;  2Y6E A;  1MDW A;  2XU5 A;  9PAP A;  4FJC A;  3PBH A;  1KHQ A;  3D6S A;  1AYU A;  4BS5 A;  3HWN A;  5EF4 A;  5F02 A;  1MIR A;  2PAD A;  2R6N A;  4P6G A;  4AXL A;  1POP A;  5CHV A;  4YYU A;  1E2T A;  4W5B A;  1HUC B;  2HHN A;  1NPZ A;  2YJ2 A;  1PPN A;  2HD5 A;  3N3K A;  3TNX A;  2PRE A;  3BPF A;  4MZS A;  3BCN A;  3IUT A;  3WXF A;  2DC7 A;  3O1G A;  2JQG R;  4N79 A;  1IWD A;  2C0Y A;  3CBK A;  3F5V A;  4DMX A;  3RVX A;  4I04 A;  1KFX L;  4W4U A;  1Y08 A;  3OIS A;  3OF9 A;  4CDD B;  1TU6 A;  2GFO A;  4I07 A;  4WA6 A;  3H8C A;  3CBJ A;  4OEL A;  3S3R A;  2XU3 A;  1PPD A;  4FIP A;  2AVW A;  3KWZ A;  1ICF A;  4PP1 A;  1O0E A;  2BSZ A;  1DF0 A;  3QSD A;  2E01 A;  3BWK A;  1F2B A;  3K8U A;  3P5W A;  2O6X A;  4K7C A;  2ATO A;  4KLB A;  1F29 A;  2PBH A;  1ATK A;  1F2C A;  1PIP A;  3KW9 A;  1NB5 A;  2FRQ A;  2G6D A;  1BP4 A;  3K24 A;  4YYQ A;  4X6H A;  1U9W A;  4I05 A;  1CVZ A;  1TL9 A;  3KFQ A;  3IV2 A;  1M6D A;  1YK8 A;  5FPW A;  3E1Z B;  2R9N A;  4BS6 A;  2IBI A;  1GMY A;  3H6S A;  1EWM A;  1CTE A;  4YYV A;  2AUZ A;  2NQD B;  3P5X A;  4X6I A;  1QOL A;  3H7D A;  4MSX A;  1AIM A;  3NHE A;  3BC3 A;  1Q6K A;  1ME3 A;  2BDL A;  1PPO A;  3LFY A;  1U5I A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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