4I05A

Structure of intermediate processing form of cathepsin b1 from schistosoma mansoni
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
277
structure length
276
Chain Sequence
GARREEPDLRRTRRPTVDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSWAFGAVEAMSDRSCIQSGGKQNVELSAVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGRDECSIESEVTAGRIN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch
pubmed doi rcsb
molecule tags Hydrolase
source organism Schistosoma mansoni
molecule keywords Cathepsin B-like peptidase (C01 family)
total genus 95
structure length 276
sequence length 277
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 2012-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4i05A00
3KX1A 1PXVA 1JQPA 1PIPA 2YJBA 4W5BA 2CIOA 1F29A 1QOLA 1EF7A 1TU6A 3BPMA 3LFYA 2H7JA 2PNSA 1AU0A 2R9OA 2G6DA 1FH0A 1YK7A 2FO5A 1IWDA 4N4ZA 2AUXA 1KHQA 1U9QX 3IV2A 2R9CA 1CVZA 4KLBA 2NQGA 5K16A 3C9EA 2FTDA 4CDDB 1KFUL 4QRVA 2YJ2A 2P86A 3MHHA 2P0RA 2DJFB 1ME4A 4OEMA 1F2BA 2R6NA 5JH3A 3N3GA 3KKUA 4PADA 4PI3A 1ITOA 1Y08A 3OVZA 1POPA 1GCBA 5CHVA 1NB3A 2B1MA 2AS8A 1BQIA 3H89A 2DZYA 2R9MA 3F75A 1CQDA 3DF0A 3KSEA 1Y4HA 1DEUA 2DCAA 1YT7A 5EF4A 3N3KA 2HXZA 4QH6A 1X9YA 3CBKA 4YYUA 3O1GA 5EGWA 4XR7A 2AYNA 7PCKA 2FYEA 3CH3X 4QBBA 2NQIA 1KHPA 1SNKA 3TNXA 5PADA 2YJCA 5CVOB 1MHWA 1EWOA 5CVMA 1NLJA 1PPPA 3PW3A 2FRAA 4P6GA 3K8UA 4YVAA 1TL9A 3M99A 3KWBX 4W4UA 2DZZA 3WXGA 1CPJA 3IUTA 1NL6A 2R9FA 1M6DA 1ZCMA 2NQAA 3O0UA 1NB5A 1PCIA 2OP3A 1TLOA 3OF8A 4YYQA 3U8EA 3RVVA 3PDFA 1CB5A 1QDQA 4BQVA 1PPNA 3RVXA 2FRQA 1AYWA 6PADA 3K9MA 1AU2A 4Q8GA 4N79A 1STFE 2AU1A 1O0EA 4YV8A 3P5VA 4N8WA 2F1GA 2XU5A 1F2CA 1MS6A 2PBHA 4G54A 4BPVA 2G7YA 1GLOA 4ZUXU 1AU3A 3BCNA 4FK5A 2FQ9A 3P5UA 2PREA 5CHTA 8PCHA 3I3TA 2DCBA 1MIRA 1U9VA 4FIPA 4BS6A 3MORA 1PPOA 1Q6KA 3HD3A 2GFOA 1CTEA 2F7DA 1ZIVA 1SP4B 1BP4A 1QXPA 1ME3A 1ICFA 4FJCA 4XUIA 2ATOA 2NQDB 3V6EA 3IEJA 2Y6EA 4DMXA 2DC9A 3CH2X 1PADA 2DCDA 2AIMA 3E1ZB 4MSXA 3IHPA 5CVNB 3P5XA 3WXEA 2WBFX 1MEMA 2DCCA 2YJ9A 3KFQA 1EWLA 2HHNA 4X6IA 2OZ2A 2IBIA 1PBHA 4OELA 3N4CA 1DF0A 1AU4A 2XU1A 4QRGA 3H8BA 2AUZA 3HHIA 1BY8A 4YYWA 2DC8A 3BWKA 4Q8HA 2E03A 3OF9A 1U5IA 3IMAA 1U9XA 1AYVA 1QMYA 4X6JA 3MTNA 1AECA 3RVWA 3ERVA 2O6XA 3USVA 3NHEA 1KFXL 3ZUAA 2C0YA 2HD5A 1CJLA 4QRXA 4AXLA 3D6SA 1GECE 4W5CA 2ACTA 2HH5A 4MZSA 2E00A 3QT4A 3V6CA 4CZWA 4CDFB 3IOQA 4CDEB 2Y5BA 2VHSA 3QSDA 9PAPA 1EWPA 3OISA 5J94A 2XU4A 1F2AA 2G8EA 1VJVA 4AXMA 4DMYA 4RY2A 2E02A 2DC7A 3BPFA 2DJGB 3MHSA 3GCBA 1MDWA 1YK8A 1CV8A 2YJ8A 4HWYA 1EWMA 3P5WA 4WA6A 4CDCB 2FUDA 4BS5A 1A6RA 1BGOA 3BC3A 1THEA 2PADA 3KW9A 2E01A 2XU3A 1NPZA 2R9NA 1PPDA 1AYUA 3PNRA 4K7CA 1NQCA 3LXSA 3B79A 2JQGR 3QJ3A 5JA7A 2IPPB 1HUCB 1VSNA 4P6EA 4PP2E 4I05A 3CBJA 3K24A 3BOWA 3HHAA 2G8JA 2FT2A 3OVXA 3HWNA 1U9WA 3WXFA 2CB5A 3KWZA 1KXRA 2BDLA 4I04A 2BDZA 4MZOA 3I06A 1AIMA 3H8CA 1GMYA 1YALA 4YYSA 5A24A 3AI8A 2AVWA 3H7DA 1MEGA 1XKGA 2OULA 1K3BB 1PE6A 2B1NA 5FPWA 5F02A 3F5VA 4I07A 2AYOA 4PP1A 3H6SA 3S3RA 2JQFR 4YYRA 4YYVA 1ATKA 2P7UA 1CS8A 2GHUA 4X6HA 2VHFA 2DC6A 3PBHA 4BSQA 1CSBB 1S4VA 3S3QA 1YVBA 2ARYA
chains in the Genus database with same CATH superfamily
3KX1A 1PXVA 1DKIA 1JQPA 4RF0A 1PIPA 2YJBA 4W5BA 4OW0A 2CIOA 1F29A 1QOLA 1EF7A 3IFUA 1TU6A 3BPMA 3LFYA 2H7JA 2PNSA 1AU0A 2R9OA 2G6DA 1FH0A 1YK7A 2FO5A 3E9SA 5EZQA 1IWDA 4N4ZA 2AUXA 1KHQA 1U9QX 3IV2A 2R9CA 1CVZA 4KLBA 2NQGA 5K16A 3C9EA 2FTDA 4CDDB 1KFUL 4QRVA 2YJ2A 2P86A 1PVJA 3MHHA 2P0RA 2DJFB 3PHXA 1ME4A 4OEMA 1F2BA 2R6NA 5JH3A 3N3GA 3KKUA 4PADA 4PI3A 1ITOA 1Y08A 3OVZA 1POPA 1GCBA 5CHVA 1NB3A 2B1MA 2AS8A 1BQIA 3H89A 2DZYA 2R9MA 3F75A 1CQDA 3DF0A 3KSEA 1Y4HA 1DEUA 2DCAA 1YT7A 5EF4A 4D8EA 4BOQA 3N3KA 2HXZA 4IP3A 4QH6A 1X9YA 3CBKA 4YYUA 3O1GA 5EGWA 4XR7A 2AYNA 7PCKA 2FYEA 3CH3X 2FE8A 3RNVA 4QBBA 2NQIA 1KHPA 1SNKA 3TNXA 5PADA 2YJCA 4BOPA 2DOSA 3PRPA 5CVOB 1MHWA 1EWOA 5CVMA 1NLJA 1PPPA 4P16A 3PW3A 4PT5A 2FRAA 4P6GA 3K8UA 4YVAA 1TL9A 3M99A 3KWBX 4M0WA 4W4UA 2DZZA 3WXGA 1CPJA 3IUTA 1NL6A 2R9FA 1M6DA 3PHUA 1ZCMA 2NQAA 3O0UA 1NB5A 1PCIA 2OP3A 1TLOA 2BU3A 3OF8A 2J7QC 4YYQA 3U8EA 3RVVA 3PDFA 1CB5A 1QDQA 3W30A 4BQVA 1PPNA 3RVXA 2FRQA 1AYWA 2J7QA 6PADA 3K9MA 1AU2A 4Q8GA 4N79A 1STFE 1YZBA 2AU1A 1O0EA 4YV8A 3BY4A 3P5VA 4N8WA 4ZTBA 2F1GA 2XU5A 1F2CA 4A5UA 1MS6A 2PBHA 4G54A 4BPVA 2G7YA 1GLOA 4ZUXU 1AU3A 3BCNA 4FK5A 2FQ9A 3P5UA 2PREA 5CHTA 8PCHA 3I3TA 2DCBA 1MIRA 1U9VA 4FIPA 4BS6A 4D8BA 3MORA 1PPOA 1Q6KA 2JRIA 3HD3A 2GFOA 1CTEA 2F7DA 1ZIVA 1SP4B 1BP4A 1QXPA 1ME3A 1ICFA 4FJCA 4XUIA 2ATOA 3TRKA 2NQDB 3V6EA 3IEJA 2Y6EA 4DMXA 2DC9A 3CH2X 3O65A 1PADA 2DCDA 2AIMA 3E1ZB 4MSXA 3IHPA 5CVNB 3P5XA 3WXEA 2WBFX 1MEMA 3W31A 2HWKA 4MI7A 2DCCA 2YJ9A 3KFQA 1EWLA 3OQCA 2HHNA 4X6IA 2OZ2A 2IBIA 1PBHA 4OELA 5KO3A 3N4CA 1DF0A 4MM3B 1AU4A 2XU1A 4QRGA 3H8BA 2AUZA 3HHIA 1BY8A 4YYWA 2DC8A 3BWKA 4Q8HA 2E03A 3OF9A 3MTVA 1U5IA 3BBAA 3IMAA 4HXDB 1U9XA 1AYVA 1QMYA 4X6JA 3MTNA 4RF1A 5E6JA 1AECA 3RVWA 3ERVA 2O6XA 4REZA 3USVA 3MP2A 3NHEA 1KFXL 3ZUAA 2C0YA 2HD5A 1CJLA 4QRXA 4AXLA 2JTCA 3D6SA 1GECE 4W5CA 4BOZA 2ACTA 2HH5A 4MZSA 2E00A 3QT4A 3V6CA 4CZWA 3PT2A 1UKFA 4CDFB 4WURA 3IOQA 4CDEB 4OVZA 2AGAA 2Y5BA 2VHSA 3QSDA 9PAPA 1EWPA 3OISA 5J94A 2XU4A 1F2AA 2G8EA 1VJVA 4AXMA 4DMYA 4RY2A 2E02A 2DC7A 3BPFA 2DJGB 3MHSA 3GCBA 1MDWA 1YK8A 1CV8A 2YJ8A 4HWYA 3MJ5A 2BTWA 1EWMA 3P5WA 4WA6A 4CDCB 2FUDA 4BS5A 5JZEA 1A6RA 1BGOA 3BC3A 1THEA 5EZSA 2PADA 3KW9A 4GUAA 2E01A 2XU3A 3B21A 4RKXA 3TMPA 4R3DA 1NPZA 2R9NA 1PPDA 4BOUA 1AYUA 3PNRA 4K7CA 1NQCA 3LXSA 3B79A 2JQGR 3QJ3A 5JA7A 2IPPB 4OVZB 1HUCB 1VSNA 4P6EA 4PP2E 4I05A 3ZNHA 3CBJA 3K24A 3BOWA 3HHAA 2G8JA 4D8IA 2FT2A 2UZJA 3OVXA 3HWNA 1U9WA 3WXFA 2CB5A 3KWZA 2BTWB 1KXRA 4BOSA 2BDLA 4I04A 2BDZA 4MZOA 3I06A 1AIMA 3H8CA 1GMYA 1YALA 4RNAA 4YYSA 5A24A 3C0RA 3PSEA 3AI8A 2AVWA 3H7DA 1MEGA 1XKGA 2OULA 1K3BB 1PE6A 2B1NA 3PHWA 3BB7A 5FPWA 5F02A 3F5VA 4I07A 2AYOA 4PP1A 3H6SA 4XZXA 3S3RA 2JQFR 4YYRA 4YYVA 1ATKA 2P7UA 1CS8A 2GHUA 4X6HA 2VHFA 2DC6A 3PBHA 4BSQA 1CSBB 1S4VA 3S3QA 1YVBA 4IUMA 2ARYA 2Z84A 3PRMA
chains in the Genus database with same CATH topology
3KX1A 1PXVA 1JQPA 1PIPA 2YJBA 4W5BA 1GX3A 2CIOA 1F29A 1QOLA 1EF7A 1TU6A 3BPMA 3LFYA 2H7JA 2PNSA 1AU0A 2R9OA 2G6DA 1FH0A 1YK7A 2FO5A 2VFCA 1IWDA 4N4ZA 2AUXA 1KHQA 1U9QX 3IV2A 2R9CA 1CVZA 4KLBA 2NQGA 5K16A 3C9EA 2FTDA 4CDDB 1KFUL 4QRVA 2YJ2A 2P86A 3MHHA 2P0RA 2DJFB 1ME4A 4OEMA 1F2BA 2R6NA 5JH3A 3N3GA 3KKUA 4PADA 4PI3A 1ITOA 1Y08A 3OVZA 1POPA 1GCBA 5CHVA 1NB3A 2B1MA 2AS8A 1BQIA 3H89A 2DZYA 4GUZA 2R9MA 3F75A 1CQDA 3DF0A 3KSEA 1Y4HA 1DEUA 2DCAA 1YT7A 5EF4A 3N3KA 2HXZA 4QH6A 1X9YA 3CBKA 4YYUA 3O1GA 5EGWA 4XR7A 2AYNA 7PCKA 2FYEA 3CH3X 4QBBA 2NQIA 1KHPA 1SNKA 3TNXA 5PADA 2YJCA 5CVOB 1MHWA 1EWOA 5CVMA 1NLJA 1PPPA 3PW3A 2FRAA 4P6GA 3K8UA 4YVAA 1TL9A 3M99A 3KWBX 4W4UA 2DZZA 3WXGA 1CPJA 3IUTA 1NL6A 2R9FA 1M6DA 1ZCMA 2NQAA 3O0UA 1NB5A 1PCIA 4NV8A 2OP3A 1TLOA 3OF8A 4YYQA 3U8EA 3RVVA 2VFBA 4NV7A 3PDFA 1CB5A 1QDQA 4BQVA 1PPNA 3RVXA 2FRQA 1AYWA 6PADA 3K9MA 1AU2A 4Q8GA 4N79A 1STFE 2AU1A 1O0EA 4YV8A 3P5VA 4N8WA 2F1GA 2XU5A 1F2CA 1MS6A 2PBHA 4G54A 4BPVA 2G7YA 1GLOA 4ZUXU 1AU3A 3BCNA 4FK5A 2FQ9A 3P5UA 2PREA 5CHTA 8PCHA 3I3TA 2DCBA 1MIRA 1U9VA 4FIPA 4BS6A 3MORA 1W6FA 1PPOA 1Q6KA 3HD3A 2GFOA 1CTEA 2F7DA 1ZIVA 1SP4B 1BP4A 1QXPA 1ME3A 1ICFA 4FJCA 4XUIA 2ATOA 2NQDB 3V6EA 3IEJA 2Y6EA 4DMXA 2DC9A 3CH2X 1PADA 2DCDA 2AIMA 3E1ZB 4MSXA 3IHPA 5CVNB 1W4TA 3P5XA 3WXEA 2WBFX 1MEMA 2DCCA 2YJ9A 3KFQA 1EWLA 2HHNA 4X6IA 2OZ2A 2IBIA 1PBHA 3D9WA 4OELA 3N4CA 1DF0A 1AU4A 2XU1A 4QRGA 3H8BA 2AUZA 3HHIA 1BY8A 4YYWA 2DC8A 3BWKA 4Q8HA 2E03A 3OF9A 1U5IA 3IMAA 1U9XA 1AYVA 1QMYA 4X6JA 3MTNA 1AECA 3RVWA 3ERVA 2O6XA 3USVA 3NHEA 1KFXL 3ZUAA 2C0YA 2HD5A 1CJLA 4QRXA 4AXLA 3D6SA 1GECE 1E2TA 4W5CA 2ACTA 2HH5A 4MZSA 2E00A 3QT4A 3V6CA 4BGFA 4CZWA 4CDFB 3IOQA 4CDEB 2Y5BA 2VHSA 3QSDA 9PAPA 1EWPA 3OISA 5J94A 2XU4A 1F2AA 2G8EA 1VJVA 4AXMA 4DMYA 4RY2A 2E02A 2DC7A 3BPFA 2DJGB 3MHSA 3GCBA 1MDWA 1YK8A 1CV8A 2YJ8A 4HWYA 1EWMA 3P5WA 4WA6A 4CDCB 2FUDA 4BS5A 1A6RA 1BGOA 3BC3A 1THEA 2PADA 3KW9A 2E01A 2XU3A 1NPZA 2R9NA 1PPDA 1AYUA 3PNRA 4K7CA 1NQCA 3LXSA 3B79A 2JQGR 3QJ3A 5JA7A 2IPPB 1HUCB 1VSNA 4P6EA 4C5PA 4PP2E 4I05A 3CBJA 3K24A 3BOWA 3HHAA 2G8JA 2FT2A 3OVXA 3HWNA 1U9WA 3WXFA 2CB5A 3KWZA 1KXRA 2BDLA 4I04A 2BDZA 4MZOA 3I06A 1AIMA 3H8CA 1GMYA 3LTWA 1YALA 4YYSA 5A24A 3AI8A 4B55A 2AVWA 3H7DA 1MEGA 1XKGA 2OULA 1K3BB 1PE6A 2B1NA 5FPWA 5F02A 2BSZA 3F5VA 4I07A 2AYOA 4PP1A 3H6SA 3S3RA 2JQFR 4YYRA 4YYVA 1W5RA 1ATKA 2P7UA 1CS8A 2GHUA 4X6HA 2VHFA 2DC6A 3PBHA 4BSQA 1CSBB 1S4VA 3S3QA 1YVBA 2ARYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KX1 A;  1PXV A;  1JQP A;  1PIP A;  2YJB A;  4W5B A;  2CIO A;  1F29 A;  1QOL A;  1EF7 A;  1TU6 A;  3BPM A;  3LFY A;  2H7J A;  2PNS A;  1AU0 A;  2R9O A;  2G6D A;  1FH0 A;  1YK7 A;  2FO5 A;  1IWD A;  4N4Z A;  2AUX A;  1KHQ A;  1U9Q X;  3IV2 A;  2R9C A;  1CVZ A;  4KLB A;  2NQG A;  5K16 A;  3C9E A;  2FTD A;  4CDD B;  1KFU L;  4QRV A;  2YJ2 A;  2P86 A;  3MHH A;  2P0R A;  2DJF B;  1ME4 A;  4OEM A;  1F2B A;  2R6N A;  5JH3 A;  3N3G A;  3KKU A;  4PAD A;  4PI3 A;  1ITO A;  1Y08 A;  3OVZ A;  1POP A;  1GCB A;  5CHV A;  1NB3 A;  2B1M A;  2AS8 A;  1BQI A;  3H89 A;  2DZY A;  2R9M A;  3F75 A;  1CQD A;  3DF0 A;  3KSE A;  1Y4H A;  1DEU A;  2DCA A;  1YT7 A;  5EF4 A;  3N3K A;  2HXZ A;  4QH6 A;  1X9Y A;  3CBK A;  4YYU A;  3O1G A;  5EGW A;  4XR7 A;  2AYN A;  7PCK A;  2FYE A;  3CH3 X;  4QBB A;  2NQI A;  1KHP A;  1SNK A;  3TNX A;  5PAD A;  2YJC A;  5CVO B;  1MHW A;  1EWO A;  5CVM A;  1NLJ A;  1PPP A;  3PW3 A;  2FRA A;  4P6G A;  3K8U A;  4YVA A;  1TL9 A;  3M99 A;  3KWB X;  4W4U A;  2DZZ A;  3WXG A;  1CPJ A;  3IUT A;  1NL6 A;  2R9F A;  1M6D A;  1ZCM A;  2NQA A;  3O0U A;  1NB5 A;  1PCI A;  2OP3 A;  1TLO A;  3OF8 A;  4YYQ A;  3U8E A;  3RVV A;  3PDF A;  1CB5 A;  1QDQ A;  4BQV A;  1PPN A;  3RVX A;  2FRQ A;  1AYW A;  6PAD A;  3K9M A;  1AU2 A;  4Q8G A;  4N79 A;  1STF E;  2AU1 A;  1O0E A;  4YV8 A;  3P5V A;  4N8W A;  2F1G A;  2XU5 A;  1F2C A;  1MS6 A;  2PBH A;  4G54 A;  4BPV A;  2G7Y A;  1GLO A;  4ZUX U;  1AU3 A;  3BCN A;  4FK5 A;  2FQ9 A;  3P5U A;  2PRE A;  5CHT A;  8PCH A;  3I3T A;  2DCB A;  1MIR A;  1U9V A;  4FIP A;  4BS6 A;  3MOR A;  1PPO A;  1Q6K A;  3HD3 A;  2GFO A;  1CTE A;  2F7D A;  1ZIV A;  1SP4 B;  1BP4 A;  1QXP A;  1ME3 A;  1ICF A;  4FJC A;  4XUI A;  2ATO A;  2NQD B;  3V6E A;  3IEJ A;  2Y6E A;  4DMX A;  2DC9 A;  3CH2 X;  1PAD A;  2DCD A;  2AIM A;  3E1Z B;  4MSX A;  3IHP A;  5CVN B;  3P5X A;  3WXE A;  2WBF X;  1MEM A;  2DCC A;  2YJ9 A;  3KFQ A;  1EWL A;  2HHN A;  4X6I A;  2OZ2 A;  2IBI A;  1PBH A;  4OEL A;  3N4C A;  1DF0 A;  1AU4 A;  2XU1 A;  4QRG A;  3H8B A;  2AUZ A;  3HHI A;  1BY8 A;  4YYW A;  2DC8 A;  3BWK A;  4Q8H A;  2E03 A;  3OF9 A;  1U5I A;  3IMA A;  1U9X A;  1AYV A;  1QMY A;  4X6J A;  3MTN A;  1AEC A;  3RVW A;  3ERV A;  2O6X A;  3USV A;  3NHE A;  1KFX L;  3ZUA A;  2C0Y A;  2HD5 A;  1CJL A;  4QRX A;  4AXL A;  3D6S A;  1GEC E;  4W5C A;  2ACT A;  2HH5 A;  4MZS A;  2E00 A;  3QT4 A;  3V6C A;  4CZW A;  4CDF B;  3IOQ A;  4CDE B;  2Y5B A;  2VHS A;  3QSD A;  9PAP A;  1EWP A;  3OIS A;  5J94 A;  2XU4 A;  1F2A A;  2G8E A;  1VJV A;  4AXM A;  4DMY A;  4RY2 A;  2E02 A;  2DC7 A;  3BPF A;  2DJG B;  3MHS A;  3GCB A;  1MDW A;  1YK8 A;  1CV8 A;  2YJ8 A;  4HWY A;  1EWM A;  3P5W A;  4WA6 A;  4CDC B;  2FUD A;  4BS5 A;  1A6R A;  1BGO A;  3BC3 A;  1THE A;  2PAD A;  3KW9 A;  2E01 A;  2XU3 A;  1NPZ A;  2R9N A;  1PPD A;  1AYU A;  3PNR A;  4K7C A;  1NQC A;  3LXS A;  3B79 A;  2JQG R;  3QJ3 A;  5JA7 A;  2IPP B;  1HUC B;  1VSN A;  4P6E A;  4PP2 E;  4I05 A;  3CBJ A;  3K24 A;  3BOW A;  3HHA A;  2G8J A;  2FT2 A;  3OVX A;  3HWN A;  1U9W A;  3WXF A;  2CB5 A;  3KWZ A;  1KXR A;  2BDL A;  4I04 A;  2BDZ A;  4MZO A;  3I06 A;  1AIM A;  3H8C A;  1GMY A;  1YAL A;  4YYS A;  5A24 A;  3AI8 A;  2AVW A;  3H7D A;  1MEG A;  1XKG A;  2OUL A;  1K3B B;  1PE6 A;  2B1N A;  5FPW A;  5F02 A;  3F5V A;  4I07 A;  2AYO A;  4PP1 A;  3H6S A;  3S3R A;  2JQF R;  4YYR A;  4YYV A;  1ATK A;  2P7U A;  1CS8 A;  2GHU A;  4X6H A;  2VHF A;  2DC6 A;  3PBH A;  4BSQ A;  1CSB B;  1S4V A;  3S3Q A;  1YVB A;  2ARY A; 
#chains in the Genus database with same CATH topology
 3KX1 A;  1PXV A;  1DKI A;  1JQP A;  4RF0 A;  1PIP A;  2YJB A;  4W5B A;  4OW0 A;  2CIO A;  1F29 A;  1QOL A;  1EF7 A;  3IFU A;  1TU6 A;  3BPM A;  3LFY A;  2H7J A;  2PNS A;  1AU0 A;  2R9O A;  2G6D A;  1FH0 A;  1YK7 A;  2FO5 A;  3E9S A;  5EZQ A;  1IWD A;  4N4Z A;  2AUX A;  1KHQ A;  1U9Q X;  3IV2 A;  2R9C A;  1CVZ A;  4KLB A;  2NQG A;  5K16 A;  3C9E A;  2FTD A;  4CDD B;  1KFU L;  4QRV A;  2YJ2 A;  2P86 A;  1PVJ A;  3MHH A;  2P0R A;  2DJF B;  3PHX A;  1ME4 A;  4OEM A;  1F2B A;  2R6N A;  5JH3 A;  3N3G A;  3KKU A;  4PAD A;  4PI3 A;  1ITO A;  1Y08 A;  3OVZ A;  1POP A;  1GCB A;  5CHV A;  1NB3 A;  2B1M A;  2AS8 A;  1BQI A;  3H89 A;  2DZY A;  2R9M A;  3F75 A;  1CQD A;  3DF0 A;  3KSE A;  1Y4H A;  1DEU A;  2DCA A;  1YT7 A;  5EF4 A;  4D8E A;  4BOQ A;  3N3K A;  2HXZ A;  4IP3 A;  4QH6 A;  1X9Y A;  3CBK A;  4YYU A;  3O1G A;  5EGW A;  4XR7 A;  2AYN A;  7PCK A;  2FYE A;  3CH3 X;  2FE8 A;  3RNV A;  4QBB A;  2NQI A;  1KHP A;  1SNK A;  3TNX A;  5PAD A;  2YJC A;  4BOP A;  2DOS A;  3PRP A;  5CVO B;  1MHW A;  1EWO A;  5CVM A;  1NLJ A;  1PPP A;  4P16 A;  3PW3 A;  4PT5 A;  2FRA A;  4P6G A;  3K8U A;  4YVA A;  1TL9 A;  3M99 A;  3KWB X;  4M0W A;  4W4U A;  2DZZ A;  3WXG A;  1CPJ A;  3IUT A;  1NL6 A;  2R9F A;  1M6D A;  3PHU A;  1ZCM A;  2NQA A;  3O0U A;  1NB5 A;  1PCI A;  2OP3 A;  1TLO A;  2BU3 A;  3OF8 A;  2J7Q C;  4YYQ A;  3U8E A;  3RVV A;  3PDF A;  1CB5 A;  1QDQ A;  3W30 A;  4BQV A;  1PPN A;  3RVX A;  2FRQ A;  1AYW A;  2J7Q A;  6PAD A;  3K9M A;  1AU2 A;  4Q8G A;  4N79 A;  1STF E;  1YZB A;  2AU1 A;  1O0E A;  4YV8 A;  3BY4 A;  3P5V A;  4N8W A;  4ZTB A;  2F1G A;  2XU5 A;  1F2C A;  4A5U A;  1MS6 A;  2PBH A;  4G54 A;  4BPV A;  2G7Y A;  1GLO A;  4ZUX U;  1AU3 A;  3BCN A;  4FK5 A;  2FQ9 A;  3P5U A;  2PRE A;  5CHT A;  8PCH A;  3I3T A;  2DCB A;  1MIR A;  1U9V A;  4FIP A;  4BS6 A;  4D8B A;  3MOR A;  1PPO A;  1Q6K A;  2JRI A;  3HD3 A;  2GFO A;  1CTE A;  2F7D A;  1ZIV A;  1SP4 B;  1BP4 A;  1QXP A;  1ME3 A;  1ICF A;  4FJC A;  4XUI A;  2ATO A;  3TRK A;  2NQD B;  3V6E A;  3IEJ A;  2Y6E A;  4DMX A;  2DC9 A;  3CH2 X;  3O65 A;  1PAD A;  2DCD A;  2AIM A;  3E1Z B;  4MSX A;  3IHP A;  5CVN B;  3P5X A;  3WXE A;  2WBF X;  1MEM A;  3W31 A;  2HWK A;  4MI7 A;  2DCC A;  2YJ9 A;  3KFQ A;  1EWL A;  3OQC A;  2HHN A;  4X6I A;  2OZ2 A;  2IBI A;  1PBH A;  4OEL A;  5KO3 A;  3N4C A;  1DF0 A;  4MM3 B;  1AU4 A;  2XU1 A;  4QRG A;  3H8B A;  2AUZ A;  3HHI A;  1BY8 A;  4YYW A;  2DC8 A;  3BWK A;  4Q8H A;  2E03 A;  3OF9 A;  3MTV A;  1U5I A;  3BBA A;  3IMA A;  4HXD B;  1U9X A;  1AYV A;  1QMY A;  4X6J A;  3MTN A;  4RF1 A;  5E6J A;  1AEC A;  3RVW A;  3ERV A;  2O6X A;  4REZ A;  3USV A;  3MP2 A;  3NHE A;  1KFX L;  3ZUA A;  2C0Y A;  2HD5 A;  1CJL A;  4QRX A;  4AXL A;  2JTC A;  3D6S A;  1GEC E;  4W5C A;  4BOZ A;  2ACT A;  2HH5 A;  4MZS A;  2E00 A;  3QT4 A;  3V6C A;  4CZW A;  3PT2 A;  1UKF A;  4CDF B;  4WUR A;  3IOQ A;  4CDE B;  4OVZ A;  2AGA A;  2Y5B A;  2VHS A;  3QSD A;  9PAP A;  1EWP A;  3OIS A;  5J94 A;  2XU4 A;  1F2A A;  2G8E A;  1VJV A;  4AXM A;  4DMY A;  4RY2 A;  2E02 A;  2DC7 A;  3BPF A;  2DJG B;  3MHS A;  3GCB A;  1MDW A;  1YK8 A;  1CV8 A;  2YJ8 A;  4HWY A;  3MJ5 A;  2BTW A;  1EWM A;  3P5W A;  4WA6 A;  4CDC B;  2FUD A;  4BS5 A;  5JZE A;  1A6R A;  1BGO A;  3BC3 A;  1THE A;  5EZS A;  2PAD A;  3KW9 A;  4GUA A;  2E01 A;  2XU3 A;  3B21 A;  4RKX A;  3TMP A;  4R3D A;  1NPZ A;  2R9N A;  1PPD A;  4BOU A;  1AYU A;  3PNR A;  4K7C A;  1NQC A;  3LXS A;  3B79 A;  2JQG R;  3QJ3 A;  5JA7 A;  2IPP B;  4OVZ B;  1HUC B;  1VSN A;  4P6E A;  4PP2 E;  4I05 A;  3ZNH A;  3CBJ A;  3K24 A;  3BOW A;  3HHA A;  2G8J A;  4D8I A;  2FT2 A;  2UZJ A;  3OVX A;  3HWN A;  1U9W A;  3WXF A;  2CB5 A;  3KWZ A;  2BTW B;  1KXR A;  4BOS A;  2BDL A;  4I04 A;  2BDZ A;  4MZO A;  3I06 A;  1AIM A;  3H8C A;  1GMY A;  1YAL A;  4RNA A;  4YYS A;  5A24 A;  3C0R A;  3PSE A;  3AI8 A;  2AVW A;  3H7D A;  1MEG A;  1XKG A;  2OUL A;  1K3B B;  1PE6 A;  2B1N A;  3PHW A;  3BB7 A;  5FPW A;  5F02 A;  3F5V A;  4I07 A;  2AYO A;  4PP1 A;  3H6S A;  4XZX A;  3S3R A;  2JQF R;  4YYR A;  4YYV A;  1ATK A;  2P7U A;  1CS8 A;  2GHU A;  4X6H A;  2VHF A;  2DC6 A;  3PBH A;  4BSQ A;  1CSB B;  1S4V A;  3S3Q A;  1YVB A;  4IUM A;  2ARY A;  2Z84 A;  3PRM A; 
#chains in the Genus database with same CATH homology
 3KX1 A;  1PXV A;  1JQP A;  1PIP A;  2YJB A;  4W5B A;  1GX3 A;  2CIO A;  1F29 A;  1QOL A;  1EF7 A;  1TU6 A;  3BPM A;  3LFY A;  2H7J A;  2PNS A;  1AU0 A;  2R9O A;  2G6D A;  1FH0 A;  1YK7 A;  2FO5 A;  2VFC A;  1IWD A;  4N4Z A;  2AUX A;  1KHQ A;  1U9Q X;  3IV2 A;  2R9C A;  1CVZ A;  4KLB A;  2NQG A;  5K16 A;  3C9E A;  2FTD A;  4CDD B;  1KFU L;  4QRV A;  2YJ2 A;  2P86 A;  3MHH A;  2P0R A;  2DJF B;  1ME4 A;  4OEM A;  1F2B A;  2R6N A;  5JH3 A;  3N3G A;  3KKU A;  4PAD A;  4PI3 A;  1ITO A;  1Y08 A;  3OVZ A;  1POP A;  1GCB A;  5CHV A;  1NB3 A;  2B1M A;  2AS8 A;  1BQI A;  3H89 A;  2DZY A;  4GUZ A;  2R9M A;  3F75 A;  1CQD A;  3DF0 A;  3KSE A;  1Y4H A;  1DEU A;  2DCA A;  1YT7 A;  5EF4 A;  3N3K A;  2HXZ A;  4QH6 A;  1X9Y A;  3CBK A;  4YYU A;  3O1G A;  5EGW A;  4XR7 A;  2AYN A;  7PCK A;  2FYE A;  3CH3 X;  4QBB A;  2NQI A;  1KHP A;  1SNK A;  3TNX A;  5PAD A;  2YJC A;  5CVO B;  1MHW A;  1EWO A;  5CVM A;  1NLJ A;  1PPP A;  3PW3 A;  2FRA A;  4P6G A;  3K8U A;  4YVA A;  1TL9 A;  3M99 A;  3KWB X;  4W4U A;  2DZZ A;  3WXG A;  1CPJ A;  3IUT A;  1NL6 A;  2R9F A;  1M6D A;  1ZCM A;  2NQA A;  3O0U A;  1NB5 A;  1PCI A;  4NV8 A;  2OP3 A;  1TLO A;  3OF8 A;  4YYQ A;  3U8E A;  3RVV A;  2VFB A;  4NV7 A;  3PDF A;  1CB5 A;  1QDQ A;  4BQV A;  1PPN A;  3RVX A;  2FRQ A;  1AYW A;  6PAD A;  3K9M A;  1AU2 A;  4Q8G A;  4N79 A;  1STF E;  2AU1 A;  1O0E A;  4YV8 A;  3P5V A;  4N8W A;  2F1G A;  2XU5 A;  1F2C A;  1MS6 A;  2PBH A;  4G54 A;  4BPV A;  2G7Y A;  1GLO A;  4ZUX U;  1AU3 A;  3BCN A;  4FK5 A;  2FQ9 A;  3P5U A;  2PRE A;  5CHT A;  8PCH A;  3I3T A;  2DCB A;  1MIR A;  1U9V A;  4FIP A;  4BS6 A;  3MOR A;  1W6F A;  1PPO A;  1Q6K A;  3HD3 A;  2GFO A;  1CTE A;  2F7D A;  1ZIV A;  1SP4 B;  1BP4 A;  1QXP A;  1ME3 A;  1ICF A;  4FJC A;  4XUI A;  2ATO A;  2NQD B;  3V6E A;  3IEJ A;  2Y6E A;  4DMX A;  2DC9 A;  3CH2 X;  1PAD A;  2DCD A;  2AIM A;  3E1Z B;  4MSX A;  3IHP A;  5CVN B;  1W4T A;  3P5X A;  3WXE A;  2WBF X;  1MEM A;  2DCC A;  2YJ9 A;  3KFQ A;  1EWL A;  2HHN A;  4X6I A;  2OZ2 A;  2IBI A;  1PBH A;  3D9W A;  4OEL A;  3N4C A;  1DF0 A;  1AU4 A;  2XU1 A;  4QRG A;  3H8B A;  2AUZ A;  3HHI A;  1BY8 A;  4YYW A;  2DC8 A;  3BWK A;  4Q8H A;  2E03 A;  3OF9 A;  1U5I A;  3IMA A;  1U9X A;  1AYV A;  1QMY A;  4X6J A;  3MTN A;  1AEC A;  3RVW A;  3ERV A;  2O6X A;  3USV A;  3NHE A;  1KFX L;  3ZUA A;  2C0Y A;  2HD5 A;  1CJL A;  4QRX A;  4AXL A;  3D6S A;  1GEC E;  1E2T A;  4W5C A;  2ACT A;  2HH5 A;  4MZS A;  2E00 A;  3QT4 A;  3V6C A;  4BGF A;  4CZW A;  4CDF B;  3IOQ A;  4CDE B;  2Y5B A;  2VHS A;  3QSD A;  9PAP A;  1EWP A;  3OIS A;  5J94 A;  2XU4 A;  1F2A A;  2G8E A;  1VJV A;  4AXM A;  4DMY A;  4RY2 A;  2E02 A;  2DC7 A;  3BPF A;  2DJG B;  3MHS A;  3GCB A;  1MDW A;  1YK8 A;  1CV8 A;  2YJ8 A;  4HWY A;  1EWM A;  3P5W A;  4WA6 A;  4CDC B;  2FUD A;  4BS5 A;  1A6R A;  1BGO A;  3BC3 A;  1THE A;  2PAD A;  3KW9 A;  2E01 A;  2XU3 A;  1NPZ A;  2R9N A;  1PPD A;  1AYU A;  3PNR A;  4K7C A;  1NQC A;  3LXS A;  3B79 A;  2JQG R;  3QJ3 A;  5JA7 A;  2IPP B;  1HUC B;  1VSN A;  4P6E A;  4C5P A;  4PP2 E;  4I05 A;  3CBJ A;  3K24 A;  3BOW A;  3HHA A;  2G8J A;  2FT2 A;  3OVX A;  3HWN A;  1U9W A;  3WXF A;  2CB5 A;  3KWZ A;  1KXR A;  2BDL A;  4I04 A;  2BDZ A;  4MZO A;  3I06 A;  1AIM A;  3H8C A;  1GMY A;  3LTW A;  1YAL A;  4YYS A;  5A24 A;  3AI8 A;  4B55 A;  2AVW A;  3H7D A;  1MEG A;  1XKG A;  2OUL A;  1K3B B;  1PE6 A;  2B1N A;  5FPW A;  5F02 A;  2BSZ A;  3F5V A;  4I07 A;  2AYO A;  4PP1 A;  3H6S A;  3S3R A;  2JQF R;  4YYR A;  4YYV A;  1W5R A;  1ATK A;  2P7U A;  1CS8 A;  2GHU A;  4X6H A;  2VHF A;  2DC6 A;  3PBH A;  4BSQ A;  1CSB B;  1S4V A;  3S3Q A;  1YVB A;  2ARY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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