4MZSA

Mouse cathepsin s with covalent ligand (3s,4s)-1-[(2-chlorophenyl)sulfonyl]-n-[(2e)-2-iminoethyl]-4-(morpholin-4-ylcarbonyl)pyrrolidine-3-carboxamide
Total Genus 66
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
66
sequence length
218
structure length
218
Chain Sequence
LPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Mus musculus
molecule keywords Cathepsin S
total genus 66
structure length 218
sequence length 218
chains with identical sequence B
ec nomenclature ec 3.4.22.27: Cathepsin S.
pdb deposition date 2013-09-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4mzsA00
2DCDA 4KLBA 4PADA 1F2CA 5K16A 3M99A 3DF0A 2WBFX 1U5IA 2ACTA 2Y6EA 1AYVA 1TLOA 4Q8GA 2ATOA 4N4ZA 3C9EA 1CB5A 3MTNA 1VJVA 3B79A 2AIMA 4W4UA 1QOLA 2CB5A 4QRGA 1BGOA 2AYOA 3IOQA 4CDFB 1AU4A 5EGWA 1AYUA 4MZSA 3P5XA 5PADA 4CZWA 1THEA 3GCBA 2FQ9A 3QJ3A 1CSBB 2H7JA 3HWNA 1CJLA 3N4CA 3P5UA 1EWMA 3KW9A 2DJFB 1GMYA 4YVAA 3WXFA 2XU4A 4MSXA 2YJ8A 1F2AA 3H89A 3CBJA 3ZUAA 2FRAA 1ME3A 1PADA 4CDCB 4I07A 3OF8A 1NL6A 2DZYA 4CDDB 3NHEA 1K3BB 2G6DA 3OISA 3IMAA 1YVBA 2R9CA 2FT2A 3K9MA 1NLJA 2G8EA 3TNXA 3IUTA 4ZUXU 1POPA 5FPWA 4HWYA 4PP1A 3H6SA 2B1NA 4YYRA 1ZIVA 4DMYA 1KHQA 5F02A 2P86A 2NQGA 1ICFA 2AVWA 5CVOB 2G8JA 2DC7A 3WXEA 2YJBA 3V6EA 2HH5A 1NB5A 5J94A 1ITOA 5JA7A 2YJ2A 1GCBA 1Q6KA 3K24A 1PPPA 2F1GA 2PNSA 2IBIA 1VSNA 1O0EA 1YALA 3KKUA 4AXLA 1CV8A 2AS8A 1TL9A 3BCNA 4OELA 4YYQA 3AI8A 1STFE 2R9OA 2VHFA 1QXPA 3O1GA 3K8UA 4X6HA 2BDLA 3LFYA 2DZZA 2P0RA 3CBKA 1M6DA 1KXRA 3KSEA 3PNRA 1MHWA 2O6XA 5EF4A 4P6EA 1EF7A 4PI3A 1AYWA 4P6GA 3BWKA 3KFQA 1GECE 1NB3A 2DC9A 3N3KA 2GFOA 3PW3A 3P5WA 4BQVA 4YYWA 4RY2A 1F2BA 1F29A 2HHNA 3WXGA 2B1MA 1CTEA 3I06A 2JQGR 2HXZA 2C0YA 2AYNA 4Q8HA 1CS8A 2NQDB 2IPPB 2FTDA 4G54A 1TU6A 3USVA 5CHVA 3H8BA 4N8WA 4N79A 4BSQA 2R6NA 3OVXA 3F75A 4BPVA 3RVXA 4I04A 3QSDA 4PP2E 2E02A 4WA6A 2R9MA 2FUDA 1ZCMA 2PREA 4MZOA 5CHTA 3E1ZB 2NQAA 1AECA 2F7DA 1QDQA 3BPFA 4QRXA 1SNKA 3H7DA 3KX1A 1PPNA 4DMXA 4W5BA 3RVVA 1AIMA 2YJ9A 1CVZA 1CPJA 2DJGB 4XUIA 3MORA 1AU2A 3P5VA 1SP4B 2E00A 5CVMA 4XR7A 3U8EA 1KFUL 2AU1A 9PAPA 1NPZA 1NQCA 2XU5A 4QBBA 5JH3A 1KHPA 3LXSA 2Y5BA 2DCCA 2FYEA 1DEUA 2YJCA 2P7UA 1FH0A 2BDZA 2GHUA 1MS6A 3CH2X 1A6RA 2ARYA 1EWPA 3F5VA 3V6CA 4FIPA 1MEMA 1PCIA 1U9WA 1PPDA 1DF0A 3KWBX 2OZ2A 1BP4A 1EWOA 2CIOA 2XU3A 1Y08A 1PE6A 3BC3A 2AUXA 4YV8A 6PADA 4YYSA 2VHSA 3CH3X 2PADA 3N3GA 1EWLA 1KFXL 2OP3A 4OEMA 4W5CA 1Y4HA 3HHAA 5A24A 3H8CA 4K7CA 4YYUA 3O0UA 2R9FA 2PBHA 3HD3A 3D6SA 2DCBA 1AU3A 2HD5A 3KWZA 2OULA 3MHSA 4QH6A 1CQDA 2DCAA 3I3TA 4I05A 2R9NA 1U9QX 1PXVA 1QMYA 1PIPA 5CVNB 4YYVA 1IWDA 1X9YA 3QT4A 2FRQA 4CDEB 2DC8A 1MDWA 2E01A 4BS5A 4BS6A 1MEGA 3IEJA 1PPOA 4AXMA 2XU1A 4FK5A 3ERVA 2JQFR 1AU0A 1ATKA 1YK7A 1YK8A 3MHHA 3BOWA 1U9XA 1BY8A 2FO5A 3PBHA 3BPMA 3S3QA 4FJCA 1MIRA 3OF9A 1GLOA 3HHIA 2NQIA 1YT7A 2G7YA 2AUZA 8PCHA 3S3RA 1BQIA 1U9VA 4QRVA 1XKGA 3IHPA 4X6IA 3IV2A 3PDFA 3RVWA 3OVZA 1PBHA 1S4VA 2DC6A 4X6JA 7PCKA 1ME4A 2E03A 1JQPA 1HUCB
chains in the Genus database with same CATH superfamily
2DCDA 4KLBA 3TRKA 4PADA 1F2CA 3PRPA 5K16A 3M99A 3DF0A 4MM3B 5KO3A 2WBFX 1U5IA 2ACTA 2Y6EA 1AYVA 1TLOA 4Q8GA 2ATOA 4N4ZA 3C9EA 1CB5A 3MTNA 1PVJA 1VJVA 3B79A 2AIMA 4W4UA 4BOUA 1QOLA 2CB5A 4QRGA 2HWKA 1BGOA 2AYOA 4MI7A 3IOQA 4R3DA 4CDFB 1AU4A 5EGWA 1AYUA 4MZSA 3P5XA 5PADA 4CZWA 1THEA 3GCBA 2FQ9A 3QJ3A 1CSBB 2H7JA 3HWNA 1CJLA 3N4CA 4PT5A 3P5UA 1EWMA 3KW9A 2DJFB 1GMYA 3PT2A 2J7QC 4IUMA 3PHWA 4YVAA 3WXFA 2XU4A 4MSXA 2YJ8A 1F2AA 3H89A 3CBJA 3ZUAA 2FRAA 1ME3A 1PADA 4CDCB 4I07A 2BTWB 3OF8A 1NL6A 2DZYA 4REZA 4CDDB 3NHEA 1K3BB 2G6DA 3OISA 3IMAA 3BBAA 1YVBA 2R9CA 2FT2A 3K9MA 1NLJA 2G8EA 3TNXA 3IUTA 4ZUXU 1POPA 5FPWA 4RKXA 4HWYA 4PP1A 3OQCA 3H6SA 2B1NA 4YYRA 1ZIVA 4DMYA 1KHQA 5E6JA 5F02A 2P86A 2NQGA 1ICFA 2AVWA 5CVOB 2G8JA 3B21A 3RNVA 2DC7A 4HXDB 3WXEA 2YJBA 3V6EA 2HH5A 1NB5A 5J94A 1ITOA 4GUAA 5JA7A 2YJ2A 1GCBA 1Q6KA 4BOSA 3K24A 1PPPA 2F1GA 2PNSA 2IBIA 1VSNA 1O0EA 1YALA 3KKUA 2UZJA 4AXLA 1CV8A 2AS8A 1TL9A 3BCNA 4A5UA 4OELA 3PHXA 4YYQA 3AI8A 1STFE 2R9OA 1DKIA 2VHFA 4XZXA 1QXPA 3O1GA 3K8UA 4X6HA 2BDLA 3LFYA 2DZZA 2P0RA 3CBKA 1M6DA 4OVZA 2BU3A 1KXRA 3KSEA 3PNRA 1MHWA 2O6XA 5EF4A 4P6EA 1EF7A 4PI3A 1AYWA 4P6GA 3BWKA 3KFQA 4BOQA 1GECE 1NB3A 2DC9A 3N3KA 2GFOA 3PW3A 3P5WA 4BQVA 4YYWA 3BB7A 4WURA 4RY2A 1F2BA 1F29A 2HHNA 3WXGA 2B1MA 1CTEA 3I06A 2JQGR 2HXZA 4RF0A 2C0YA 2AYNA 4Q8HA 1CS8A 4BOZA 2NQDB 2IPPB 2FTDA 4G54A 1TU6A 3USVA 5CHVA 3H8BA 4N8WA 4N79A 4BSQA 3PSEA 2R6NA 3OVXA 4P16A 3F75A 4BPVA 3PHUA 3RVXA 4I04A 3QSDA 4PP2E 3IFUA 2E02A 4WA6A 2R9MA 2FUDA 1ZCMA 2PREA 4MZOA 5CHTA 3E1ZB 2NQAA 1AECA 1YZBA 5EZQA 2F7DA 1QDQA 3BPFA 4QRXA 1SNKA 1UKFA 3H7DA 3KX1A 1PPNA 4DMXA 4W5BA 3RVVA 2JRIA 1AIMA 2YJ9A 3PRMA 1CVZA 1CPJA 2DJGB 4XUIA 3MORA 1AU2A 3P5VA 1SP4B 3TMPA 2E00A 5CVMA 4ZTBA 4XR7A 3U8EA 4OW0A 1KFUL 2AU1A 2J7QA 3W31A 9PAPA 1NPZA 1NQCA 4RNAA 2XU5A 4QBBA 5JH3A 1KHPA 3LXSA 2Y5BA 2BTWA 2DCCA 2FYEA 1DEUA 2YJCA 3MP2A 2P7UA 1FH0A 2BDZA 2GHUA 1MS6A 4D8IA 3CH2X 1A6RA 2ARYA 1EWPA 3F5VA 3V6CA 4FIPA 2FE8A 1MEMA 1PCIA 1U9WA 1PPDA 1DF0A 3KWBX 2OZ2A 1BP4A 1EWOA 2CIOA 2XU3A 1Y08A 1PE6A 3BC3A 2AUXA 4YV8A 6PADA 4YYSA 2VHSA 3CH3X 2AGAA 2PADA 3N3GA 5JZEA 1EWLA 1KFXL 2OP3A 4OEMA 4W5CA 1Y4HA 3HHAA 5A24A 4D8EA 3MTVA 3H8CA 4D8BA 4K7CA 4YYUA 3O0UA 2R9FA 2PBHA 5EZSA 3HD3A 3D6SA 4IP3A 2DCBA 1AU3A 2HD5A 3KWZA 2OULA 3MHSA 4M0WA 4QH6A 1CQDA 2DCAA 4BOPA 3I3TA 3E9SA 4I05A 2R9NA 1U9QX 1PXVA 1QMYA 1PIPA 5CVNB 4YYVA 1IWDA 1X9YA 3QT4A 2FRQA 4CDEB 2DC8A 1MDWA 2E01A 3W30A 4BS5A 4BS6A 1MEGA 2DOSA 3IEJA 4RF1A 1PPOA 4AXMA 2XU1A 4FK5A 3ERVA 2JQFR 1AU0A 1ATKA 1YK7A 1YK8A 3MHHA 3O65A 3BOWA 4OVZB 1U9XA 1BY8A 3C0RA 3PBHA 2FO5A 3ZNHA 3BPMA 3S3QA 4FJCA 1MIRA 3BY4A 3OF9A 1GLOA 3HHIA 2NQIA 3MJ5A 1YT7A 2G7YA 2AUZA 2Z84A 8PCHA 2JTCA 3S3RA 1BQIA 1U9VA 4QRVA 1XKGA 3IHPA 4X6IA 3IV2A 3PDFA 3RVWA 3OVZA 1PBHA 1S4VA 2DC6A 4X6JA 7PCKA 1ME4A 2E03A 1JQPA 1HUCB
chains in the Genus database with same CATH topology
2DCDA 4KLBA 4PADA 1F2CA 5K16A 3M99A 3DF0A 4NV7A 2WBFX 1U5IA 2ACTA 2Y6EA 4B55A 1AYVA 1TLOA 4Q8GA 2ATOA 4N4ZA 3C9EA 1CB5A 3MTNA 1VJVA 3B79A 2AIMA 4W4UA 1QOLA 2CB5A 4QRGA 1BGOA 2AYOA 3IOQA 4CDFB 1AU4A 5EGWA 1AYUA 4MZSA 3P5XA 5PADA 4CZWA 4C5PA 1THEA 3GCBA 2FQ9A 3QJ3A 1CSBB 2H7JA 3HWNA 1CJLA 3N4CA 3P5UA 1EWMA 3KW9A 2DJFB 1GMYA 4YVAA 3WXFA 2XU4A 4MSXA 2YJ8A 1F2AA 3H89A 3CBJA 3ZUAA 2FRAA 1ME3A 1PADA 4CDCB 4I07A 3OF8A 1NL6A 2DZYA 4CDDB 3NHEA 1K3BB 2G6DA 3OISA 3IMAA 1YVBA 1W4TA 2R9CA 2FT2A 3K9MA 1NLJA 2G8EA 3TNXA 3IUTA 4ZUXU 1POPA 5FPWA 4HWYA 4PP1A 3H6SA 2B1NA 4YYRA 1ZIVA 4DMYA 1KHQA 5F02A 2P86A 2NQGA 1ICFA 2AVWA 5CVOB 2G8JA 2DC7A 3WXEA 2YJBA 3V6EA 2HH5A 1NB5A 5J94A 1ITOA 5JA7A 2YJ2A 1GCBA 1W5RA 1Q6KA 3K24A 1PPPA 2F1GA 2PNSA 2IBIA 1VSNA 1O0EA 1YALA 2VFCA 3KKUA 4BGFA 4AXLA 1CV8A 2AS8A 1TL9A 3BCNA 4OELA 4YYQA 3AI8A 1STFE 2R9OA 2VHFA 1QXPA 3O1GA 3K8UA 4X6HA 2BDLA 3LFYA 2DZZA 2P0RA 3CBKA 1M6DA 1KXRA 3KSEA 3PNRA 1MHWA 2O6XA 5EF4A 4P6EA 1EF7A 2BSZA 1AYWA 4PI3A 4P6GA 3BWKA 3KFQA 1GECE 1NB3A 2DC9A 3N3KA 2GFOA 3PW3A 3P5WA 4BQVA 4YYWA 4RY2A 1F2BA 1F29A 2HHNA 3WXGA 2B1MA 1CTEA 3I06A 2JQGR 2HXZA 2C0YA 2AYNA 4Q8HA 1CS8A 2NQDB 2IPPB 2FTDA 4G54A 1TU6A 3USVA 5CHVA 3H8BA 4N8WA 4N79A 4BSQA 2R6NA 3OVXA 3F75A 4BPVA 3RVXA 4I04A 3QSDA 4PP2E 2E02A 4WA6A 2R9MA 2FUDA 1ZCMA 2PREA 4MZOA 5CHTA 3E1ZB 2NQAA 1AECA 2F7DA 1QDQA 3BPFA 4QRXA 1SNKA 3H7DA 3KX1A 1PPNA 4DMXA 4W5BA 3RVVA 1E2TA 1AIMA 2YJ9A 1CVZA 1CPJA 2DJGB 4XUIA 3MORA 1AU2A 3P5VA 1SP4B 2E00A 5CVMA 4XR7A 3U8EA 1KFUL 2AU1A 9PAPA 1NPZA 1NQCA 2XU5A 4QBBA 5JH3A 1KHPA 1W6FA 3LXSA 2Y5BA 3D9WA 2DCCA 2VFBA 2FYEA 1DEUA 2YJCA 2P7UA 1FH0A 2BDZA 2GHUA 1MS6A 3CH2X 1A6RA 2ARYA 1EWPA 3F5VA 4NV8A 3V6CA 4FIPA 1MEMA 1PCIA 1U9WA 1PPDA 1DF0A 3KWBX 2OZ2A 1BP4A 1EWOA 2CIOA 2XU3A 1Y08A 1PE6A 3BC3A 2AUXA 4YV8A 6PADA 4YYSA 2VHSA 3CH3X 2PADA 3N3GA 1EWLA 1KFXL 2OP3A 4OEMA 4W5CA 1Y4HA 3HHAA 5A24A 3H8CA 4K7CA 4YYUA 3O0UA 2R9FA 2PBHA 3HD3A 3D6SA 2DCBA 1AU3A 2HD5A 3KWZA 2OULA 3MHSA 4QH6A 1CQDA 2DCAA 3I3TA 3LTWA 4I05A 2R9NA 1U9QX 1PXVA 1QMYA 1PIPA 5CVNB 4YYVA 1IWDA 1X9YA 3QT4A 2FRQA 4CDEB 2DC8A 1MDWA 2E01A 4BS5A 4BS6A 1GX3A 1MEGA 3IEJA 1PPOA 4AXMA 2XU1A 4FK5A 3ERVA 2JQFR 1AU0A 1ATKA 1YK7A 1YK8A 3MHHA 3BOWA 1U9XA 1BY8A 3PBHA 2FO5A 3BPMA 3S3QA 4FJCA 1MIRA 3OF9A 1GLOA 3HHIA 2NQIA 1YT7A 2G7YA 4GUZA 2AUZA 8PCHA 3S3RA 1BQIA 1U9VA 4QRVA 1XKGA 3IHPA 4X6IA 3IV2A 3PDFA 3RVWA 3OVZA 1PBHA 1S4VA 2DC6A 4X6JA 7PCKA 1ME4A 2E03A 1JQPA 1HUCB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DCD A;  4KLB A;  4PAD A;  1F2C A;  5K16 A;  3M99 A;  3DF0 A;  2WBF X;  1U5I A;  2ACT A;  2Y6E A;  1AYV A;  1TLO A;  4Q8G A;  2ATO A;  4N4Z A;  3C9E A;  1CB5 A;  3MTN A;  1VJV A;  3B79 A;  2AIM A;  4W4U A;  1QOL A;  2CB5 A;  4QRG A;  1BGO A;  2AYO A;  3IOQ A;  4CDF B;  1AU4 A;  5EGW A;  1AYU A;  4MZS A;  3P5X A;  5PAD A;  4CZW A;  1THE A;  3GCB A;  2FQ9 A;  3QJ3 A;  1CSB B;  2H7J A;  3HWN A;  1CJL A;  3N4C A;  3P5U A;  1EWM A;  3KW9 A;  2DJF B;  1GMY A;  4YVA A;  3WXF A;  2XU4 A;  4MSX A;  2YJ8 A;  1F2A A;  3H89 A;  3CBJ A;  3ZUA A;  2FRA A;  1ME3 A;  1PAD A;  4CDC B;  4I07 A;  3OF8 A;  1NL6 A;  2DZY A;  4CDD B;  3NHE A;  1K3B B;  2G6D A;  3OIS A;  3IMA A;  1YVB A;  2R9C A;  2FT2 A;  3K9M A;  1NLJ A;  2G8E A;  3TNX A;  3IUT A;  4ZUX U;  1POP A;  5FPW A;  4HWY A;  4PP1 A;  3H6S A;  2B1N A;  4YYR A;  1ZIV A;  4DMY A;  1KHQ A;  5F02 A;  2P86 A;  2NQG A;  1ICF A;  2AVW A;  5CVO B;  2G8J A;  2DC7 A;  3WXE A;  2YJB A;  3V6E A;  2HH5 A;  1NB5 A;  5J94 A;  1ITO A;  5JA7 A;  2YJ2 A;  1GCB A;  1Q6K A;  3K24 A;  1PPP A;  2F1G A;  2PNS A;  2IBI A;  1VSN A;  1O0E A;  1YAL A;  3KKU A;  4AXL A;  1CV8 A;  2AS8 A;  1TL9 A;  3BCN A;  4OEL A;  4YYQ A;  3AI8 A;  1STF E;  2R9O A;  2VHF A;  1QXP A;  3O1G A;  3K8U A;  4X6H A;  2BDL A;  3LFY A;  2DZZ A;  2P0R A;  3CBK A;  1M6D A;  1KXR A;  3KSE A;  3PNR A;  1MHW A;  2O6X A;  5EF4 A;  4P6E A;  1EF7 A;  4PI3 A;  1AYW A;  4P6G A;  3BWK A;  3KFQ A;  1GEC E;  1NB3 A;  2DC9 A;  3N3K A;  2GFO A;  3PW3 A;  3P5W A;  4BQV A;  4YYW A;  4RY2 A;  1F2B A;  1F29 A;  2HHN A;  3WXG A;  2B1M A;  1CTE A;  3I06 A;  2JQG R;  2HXZ A;  2C0Y A;  2AYN A;  4Q8H A;  1CS8 A;  2NQD B;  2IPP B;  2FTD A;  4G54 A;  1TU6 A;  3USV A;  5CHV A;  3H8B A;  4N8W A;  4N79 A;  4BSQ A;  2R6N A;  3OVX A;  3F75 A;  4BPV A;  3RVX A;  4I04 A;  3QSD A;  4PP2 E;  2E02 A;  4WA6 A;  2R9M A;  2FUD A;  1ZCM A;  2PRE A;  4MZO A;  5CHT A;  3E1Z B;  2NQA A;  1AEC A;  2F7D A;  1QDQ A;  3BPF A;  4QRX A;  1SNK A;  3H7D A;  3KX1 A;  1PPN A;  4DMX A;  4W5B A;  3RVV A;  1AIM A;  2YJ9 A;  1CVZ A;  1CPJ A;  2DJG B;  4XUI A;  3MOR A;  1AU2 A;  3P5V A;  1SP4 B;  2E00 A;  5CVM A;  4XR7 A;  3U8E A;  1KFU L;  2AU1 A;  9PAP A;  1NPZ A;  1NQC A;  2XU5 A;  4QBB A;  5JH3 A;  1KHP A;  3LXS A;  2Y5B A;  2DCC A;  2FYE A;  1DEU A;  2YJC A;  2P7U A;  1FH0 A;  2BDZ A;  2GHU A;  1MS6 A;  3CH2 X;  1A6R A;  2ARY A;  1EWP A;  3F5V A;  3V6C A;  4FIP A;  1MEM A;  1PCI A;  1U9W A;  1PPD A;  1DF0 A;  3KWB X;  2OZ2 A;  1BP4 A;  1EWO A;  2CIO A;  2XU3 A;  1Y08 A;  1PE6 A;  3BC3 A;  2AUX A;  4YV8 A;  6PAD A;  4YYS A;  2VHS A;  3CH3 X;  2PAD A;  3N3G A;  1EWL A;  1KFX L;  2OP3 A;  4OEM A;  4W5C A;  1Y4H A;  3HHA A;  5A24 A;  3H8C A;  4K7C A;  4YYU A;  3O0U A;  2R9F A;  2PBH A;  3HD3 A;  3D6S A;  2DCB A;  1AU3 A;  2HD5 A;  3KWZ A;  2OUL A;  3MHS A;  4QH6 A;  1CQD A;  2DCA A;  3I3T A;  4I05 A;  2R9N A;  1U9Q X;  1PXV A;  1QMY A;  1PIP A;  5CVN B;  4YYV A;  1IWD A;  1X9Y A;  3QT4 A;  2FRQ A;  4CDE B;  2DC8 A;  1MDW A;  2E01 A;  4BS5 A;  4BS6 A;  1MEG A;  3IEJ A;  1PPO A;  4AXM A;  2XU1 A;  4FK5 A;  3ERV A;  2JQF R;  1AU0 A;  1ATK A;  1YK7 A;  1YK8 A;  3MHH A;  3BOW A;  1U9X A;  1BY8 A;  2FO5 A;  3PBH A;  3BPM A;  3S3Q A;  4FJC A;  1MIR A;  3OF9 A;  1GLO A;  3HHI A;  2NQI A;  1YT7 A;  2G7Y A;  2AUZ A;  8PCH A;  3S3R A;  1BQI A;  1U9V A;  4QRV A;  1XKG A;  3IHP A;  4X6I A;  3IV2 A;  3PDF A;  3RVW A;  3OVZ A;  1PBH A;  1S4V A;  2DC6 A;  4X6J A;  7PCK A;  1ME4 A;  2E03 A;  1JQP A;  1HUC B; 
#chains in the Genus database with same CATH topology
 2DCD A;  4KLB A;  3TRK A;  4PAD A;  1F2C A;  3PRP A;  5K16 A;  3M99 A;  3DF0 A;  4MM3 B;  5KO3 A;  2WBF X;  1U5I A;  2ACT A;  2Y6E A;  1AYV A;  1TLO A;  4Q8G A;  2ATO A;  4N4Z A;  3C9E A;  1CB5 A;  3MTN A;  1PVJ A;  1VJV A;  3B79 A;  2AIM A;  4W4U A;  4BOU A;  1QOL A;  2CB5 A;  4QRG A;  2HWK A;  1BGO A;  2AYO A;  4MI7 A;  3IOQ A;  4R3D A;  4CDF B;  1AU4 A;  5EGW A;  1AYU A;  4MZS A;  3P5X A;  5PAD A;  4CZW A;  1THE A;  3GCB A;  2FQ9 A;  3QJ3 A;  1CSB B;  2H7J A;  3HWN A;  1CJL A;  3N4C A;  4PT5 A;  3P5U A;  1EWM A;  3KW9 A;  2DJF B;  1GMY A;  3PT2 A;  2J7Q C;  4IUM A;  3PHW A;  4YVA A;  3WXF A;  2XU4 A;  4MSX A;  2YJ8 A;  1F2A A;  3H89 A;  3CBJ A;  3ZUA A;  2FRA A;  1ME3 A;  1PAD A;  4CDC B;  4I07 A;  2BTW B;  3OF8 A;  1NL6 A;  2DZY A;  4REZ A;  4CDD B;  3NHE A;  1K3B B;  2G6D A;  3OIS A;  3IMA A;  3BBA A;  1YVB A;  2R9C A;  2FT2 A;  3K9M A;  1NLJ A;  2G8E A;  3TNX A;  3IUT A;  4ZUX U;  1POP A;  5FPW A;  4RKX A;  4HWY A;  4PP1 A;  3OQC A;  3H6S A;  2B1N A;  4YYR A;  1ZIV A;  4DMY A;  1KHQ A;  5E6J A;  5F02 A;  2P86 A;  2NQG A;  1ICF A;  2AVW A;  5CVO B;  2G8J A;  3B21 A;  3RNV A;  2DC7 A;  4HXD B;  3WXE A;  2YJB A;  3V6E A;  2HH5 A;  1NB5 A;  5J94 A;  1ITO A;  4GUA A;  5JA7 A;  2YJ2 A;  1GCB A;  1Q6K A;  4BOS A;  3K24 A;  1PPP A;  2F1G A;  2PNS A;  2IBI A;  1VSN A;  1O0E A;  1YAL A;  3KKU A;  2UZJ A;  4AXL A;  1CV8 A;  2AS8 A;  1TL9 A;  3BCN A;  4A5U A;  4OEL A;  3PHX A;  4YYQ A;  3AI8 A;  1STF E;  2R9O A;  1DKI A;  2VHF A;  4XZX A;  1QXP A;  3O1G A;  3K8U A;  4X6H A;  2BDL A;  3LFY A;  2DZZ A;  2P0R A;  3CBK A;  1M6D A;  4OVZ A;  2BU3 A;  1KXR A;  3KSE A;  3PNR A;  1MHW A;  2O6X A;  5EF4 A;  4P6E A;  1EF7 A;  4PI3 A;  1AYW A;  4P6G A;  3BWK A;  3KFQ A;  4BOQ A;  1GEC E;  1NB3 A;  2DC9 A;  3N3K A;  2GFO A;  3PW3 A;  3P5W A;  4BQV A;  4YYW A;  3BB7 A;  4WUR A;  4RY2 A;  1F2B A;  1F29 A;  2HHN A;  3WXG A;  2B1M A;  1CTE A;  3I06 A;  2JQG R;  2HXZ A;  4RF0 A;  2C0Y A;  2AYN A;  4Q8H A;  1CS8 A;  4BOZ A;  2NQD B;  2IPP B;  2FTD A;  4G54 A;  1TU6 A;  3USV A;  5CHV A;  3H8B A;  4N8W A;  4N79 A;  4BSQ A;  3PSE A;  2R6N A;  3OVX A;  4P16 A;  3F75 A;  4BPV A;  3PHU A;  3RVX A;  4I04 A;  3QSD A;  4PP2 E;  3IFU A;  2E02 A;  4WA6 A;  2R9M A;  2FUD A;  1ZCM A;  2PRE A;  4MZO A;  5CHT A;  3E1Z B;  2NQA A;  1AEC A;  1YZB A;  5EZQ A;  2F7D A;  1QDQ A;  3BPF A;  4QRX A;  1SNK A;  1UKF A;  3H7D A;  3KX1 A;  1PPN A;  4DMX A;  4W5B A;  3RVV A;  2JRI A;  1AIM A;  2YJ9 A;  3PRM A;  1CVZ A;  1CPJ A;  2DJG B;  4XUI A;  3MOR A;  1AU2 A;  3P5V A;  1SP4 B;  3TMP A;  2E00 A;  5CVM A;  4ZTB A;  4XR7 A;  3U8E A;  4OW0 A;  1KFU L;  2AU1 A;  2J7Q A;  3W31 A;  9PAP A;  1NPZ A;  1NQC A;  4RNA A;  2XU5 A;  4QBB A;  5JH3 A;  1KHP A;  3LXS A;  2Y5B A;  2BTW A;  2DCC A;  2FYE A;  1DEU A;  2YJC A;  3MP2 A;  2P7U A;  1FH0 A;  2BDZ A;  2GHU A;  1MS6 A;  4D8I A;  3CH2 X;  1A6R A;  2ARY A;  1EWP A;  3F5V A;  3V6C A;  4FIP A;  2FE8 A;  1MEM A;  1PCI A;  1U9W A;  1PPD A;  1DF0 A;  3KWB X;  2OZ2 A;  1BP4 A;  1EWO A;  2CIO A;  2XU3 A;  1Y08 A;  1PE6 A;  3BC3 A;  2AUX A;  4YV8 A;  6PAD A;  4YYS A;  2VHS A;  3CH3 X;  2AGA A;  2PAD A;  3N3G A;  5JZE A;  1EWL A;  1KFX L;  2OP3 A;  4OEM A;  4W5C A;  1Y4H A;  3HHA A;  5A24 A;  4D8E A;  3MTV A;  3H8C A;  4D8B A;  4K7C A;  4YYU A;  3O0U A;  2R9F A;  2PBH A;  5EZS A;  3HD3 A;  3D6S A;  4IP3 A;  2DCB A;  1AU3 A;  2HD5 A;  3KWZ A;  2OUL A;  3MHS A;  4M0W A;  4QH6 A;  1CQD A;  2DCA A;  4BOP A;  3I3T A;  3E9S A;  4I05 A;  2R9N A;  1U9Q X;  1PXV A;  1QMY A;  1PIP A;  5CVN B;  4YYV A;  1IWD A;  1X9Y A;  3QT4 A;  2FRQ A;  4CDE B;  2DC8 A;  1MDW A;  2E01 A;  3W30 A;  4BS5 A;  4BS6 A;  1MEG A;  2DOS A;  3IEJ A;  4RF1 A;  1PPO A;  4AXM A;  2XU1 A;  4FK5 A;  3ERV A;  2JQF R;  1AU0 A;  1ATK A;  1YK7 A;  1YK8 A;  3MHH A;  3O65 A;  3BOW A;  4OVZ B;  1U9X A;  1BY8 A;  3C0R A;  3PBH A;  2FO5 A;  3ZNH A;  3BPM A;  3S3Q A;  4FJC A;  1MIR A;  3BY4 A;  3OF9 A;  1GLO A;  3HHI A;  2NQI A;  3MJ5 A;  1YT7 A;  2G7Y A;  2AUZ A;  2Z84 A;  8PCH A;  2JTC A;  3S3R A;  1BQI A;  1U9V A;  4QRV A;  1XKG A;  3IHP A;  4X6I A;  3IV2 A;  3PDF A;  3RVW A;  3OVZ A;  1PBH A;  1S4V A;  2DC6 A;  4X6J A;  7PCK A;  1ME4 A;  2E03 A;  1JQP A;  1HUC B; 
#chains in the Genus database with same CATH homology
 2DCD A;  4KLB A;  4PAD A;  1F2C A;  5K16 A;  3M99 A;  3DF0 A;  4NV7 A;  2WBF X;  1U5I A;  2ACT A;  2Y6E A;  4B55 A;  1AYV A;  1TLO A;  4Q8G A;  2ATO A;  4N4Z A;  3C9E A;  1CB5 A;  3MTN A;  1VJV A;  3B79 A;  2AIM A;  4W4U A;  1QOL A;  2CB5 A;  4QRG A;  1BGO A;  2AYO A;  3IOQ A;  4CDF B;  1AU4 A;  5EGW A;  1AYU A;  4MZS A;  3P5X A;  5PAD A;  4CZW A;  4C5P A;  1THE A;  3GCB A;  2FQ9 A;  3QJ3 A;  1CSB B;  2H7J A;  3HWN A;  1CJL A;  3N4C A;  3P5U A;  1EWM A;  3KW9 A;  2DJF B;  1GMY A;  4YVA A;  3WXF A;  2XU4 A;  4MSX A;  2YJ8 A;  1F2A A;  3H89 A;  3CBJ A;  3ZUA A;  2FRA A;  1ME3 A;  1PAD A;  4CDC B;  4I07 A;  3OF8 A;  1NL6 A;  2DZY A;  4CDD B;  3NHE A;  1K3B B;  2G6D A;  3OIS A;  3IMA A;  1YVB A;  1W4T A;  2R9C A;  2FT2 A;  3K9M A;  1NLJ A;  2G8E A;  3TNX A;  3IUT A;  4ZUX U;  1POP A;  5FPW A;  4HWY A;  4PP1 A;  3H6S A;  2B1N A;  4YYR A;  1ZIV A;  4DMY A;  1KHQ A;  5F02 A;  2P86 A;  2NQG A;  1ICF A;  2AVW A;  5CVO B;  2G8J A;  2DC7 A;  3WXE A;  2YJB A;  3V6E A;  2HH5 A;  1NB5 A;  5J94 A;  1ITO A;  5JA7 A;  2YJ2 A;  1GCB A;  1W5R A;  1Q6K A;  3K24 A;  1PPP A;  2F1G A;  2PNS A;  2IBI A;  1VSN A;  1O0E A;  1YAL A;  2VFC A;  3KKU A;  4BGF A;  4AXL A;  1CV8 A;  2AS8 A;  1TL9 A;  3BCN A;  4OEL A;  4YYQ A;  3AI8 A;  1STF E;  2R9O A;  2VHF A;  1QXP A;  3O1G A;  3K8U A;  4X6H A;  2BDL A;  3LFY A;  2DZZ A;  2P0R A;  3CBK A;  1M6D A;  1KXR A;  3KSE A;  3PNR A;  1MHW A;  2O6X A;  5EF4 A;  4P6E A;  1EF7 A;  2BSZ A;  1AYW A;  4PI3 A;  4P6G A;  3BWK A;  3KFQ A;  1GEC E;  1NB3 A;  2DC9 A;  3N3K A;  2GFO A;  3PW3 A;  3P5W A;  4BQV A;  4YYW A;  4RY2 A;  1F2B A;  1F29 A;  2HHN A;  3WXG A;  2B1M A;  1CTE A;  3I06 A;  2JQG R;  2HXZ A;  2C0Y A;  2AYN A;  4Q8H A;  1CS8 A;  2NQD B;  2IPP B;  2FTD A;  4G54 A;  1TU6 A;  3USV A;  5CHV A;  3H8B A;  4N8W A;  4N79 A;  4BSQ A;  2R6N A;  3OVX A;  3F75 A;  4BPV A;  3RVX A;  4I04 A;  3QSD A;  4PP2 E;  2E02 A;  4WA6 A;  2R9M A;  2FUD A;  1ZCM A;  2PRE A;  4MZO A;  5CHT A;  3E1Z B;  2NQA A;  1AEC A;  2F7D A;  1QDQ A;  3BPF A;  4QRX A;  1SNK A;  3H7D A;  3KX1 A;  1PPN A;  4DMX A;  4W5B A;  3RVV A;  1E2T A;  1AIM A;  2YJ9 A;  1CVZ A;  1CPJ A;  2DJG B;  4XUI A;  3MOR A;  1AU2 A;  3P5V A;  1SP4 B;  2E00 A;  5CVM A;  4XR7 A;  3U8E A;  1KFU L;  2AU1 A;  9PAP A;  1NPZ A;  1NQC A;  2XU5 A;  4QBB A;  5JH3 A;  1KHP A;  1W6F A;  3LXS A;  2Y5B A;  3D9W A;  2DCC A;  2VFB A;  2FYE A;  1DEU A;  2YJC A;  2P7U A;  1FH0 A;  2BDZ A;  2GHU A;  1MS6 A;  3CH2 X;  1A6R A;  2ARY A;  1EWP A;  3F5V A;  4NV8 A;  3V6C A;  4FIP A;  1MEM A;  1PCI A;  1U9W A;  1PPD A;  1DF0 A;  3KWB X;  2OZ2 A;  1BP4 A;  1EWO A;  2CIO A;  2XU3 A;  1Y08 A;  1PE6 A;  3BC3 A;  2AUX A;  4YV8 A;  6PAD A;  4YYS A;  2VHS A;  3CH3 X;  2PAD A;  3N3G A;  1EWL A;  1KFX L;  2OP3 A;  4OEM A;  4W5C A;  1Y4H A;  3HHA A;  5A24 A;  3H8C A;  4K7C A;  4YYU A;  3O0U A;  2R9F A;  2PBH A;  3HD3 A;  3D6S A;  2DCB A;  1AU3 A;  2HD5 A;  3KWZ A;  2OUL A;  3MHS A;  4QH6 A;  1CQD A;  2DCA A;  3I3T A;  3LTW A;  4I05 A;  2R9N A;  1U9Q X;  1PXV A;  1QMY A;  1PIP A;  5CVN B;  4YYV A;  1IWD A;  1X9Y A;  3QT4 A;  2FRQ A;  4CDE B;  2DC8 A;  1MDW A;  2E01 A;  4BS5 A;  4BS6 A;  1GX3 A;  1MEG A;  3IEJ A;  1PPO A;  4AXM A;  2XU1 A;  4FK5 A;  3ERV A;  2JQF R;  1AU0 A;  1ATK A;  1YK7 A;  1YK8 A;  3MHH A;  3BOW A;  1U9X A;  1BY8 A;  3PBH A;  2FO5 A;  3BPM A;  3S3Q A;  4FJC A;  1MIR A;  3OF9 A;  1GLO A;  3HHI A;  2NQI A;  1YT7 A;  2G7Y A;  4GUZ A;  2AUZ A;  8PCH A;  3S3R A;  1BQI A;  1U9V A;  4QRV A;  1XKG A;  3IHP A;  4X6I A;  3IV2 A;  3PDF A;  3RVW A;  3OVZ A;  1PBH A;  1S4V A;  2DC6 A;  4X6J A;  7PCK A;  1ME4 A;  2E03 A;  1JQP A;  1HUC B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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