4BPVA

Mouse cathepsin s with covalent ligand
Total Genus 68
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
219
structure length
219
Chain Sequence
TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKAMDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGNVNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cathepsin S Nitrile Inhibitors
rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords CATHEPSIN S
total genus 68
structure length 219
sequence length 219
chains with identical sequence B, C, D, E, K
ec nomenclature ec 3.4.22.27: Cathepsin S.
pdb deposition date 2013-05-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4bpvA00
3P5UA 3I06A 3AI8A 3H8CA 3K9MA 3KWBX 2BDZA 3F5VA 6PADA 4BSQA 3K8UA 3H89A 1MEGA 2IBIA 4AXLA 4YYSA 4G54A 3H6SA 4I04A 4W4UA 3BPMA 1PADA 2FUDA 2PREA 1KFXL 2HH5A 3H8BA 1DEUA 4MZOA 1CQDA 4QRXA 2Y6EA 1NQCA 2XU1A 1HUCB 2F7DA 1GCBA 1O0EA 2R9MA 4MZSA 4QRVA 4K7CA 4N79A 2DC6A 3PDFA 2G7YA 3HWNA 3I3TA 1PPPA 2JQFR 1MEMA 1IWDA 1ME3A 2H7JA 1ME4A 1U9WA 3IUTA 1QOLA 1MDWA 4FIPA 1NLJA 2R6NA 2R9NA 3RVXA 2DCAA 3DF0A 2F1GA 3P5XA 4YYUA 2AUXA 2XU3A 3PBHA 3OF8A 2DC8A 3GCBA 5CVMA 4PP2E 4YV8A 2YJ8A 7PCKA 1BP4A 4DMYA 1QDQA 3CH3X 2G6DA 2YJBA 1QXPA 4X6JA 4XUIA 4CDFB 1BGOA 2YJCA 3WXEA 3P5WA 5JH3A 1AU4A 3CBJA 2HD5A 1NL6A 3KSEA 3V6EA 1PPDA 2XU5A 3KX1A 3B79A 3IV2A 1CPJA 1CVZA 4XR7A 1CJLA 1YK7A 3OVXA 2R9CA 3K24A 1XKGA 4OEMA 1PPOA 3IEJA 4PP1A 2AIMA 3H7DA 1TL9A 2ACTA 2PADA 1JQPA 1STFE 4P6GA 4W5BA 1PIPA 1CSBB 3P5VA 3BWKA 4X6IA 4OELA 3OISA 1EWPA 1KXRA 1EWMA 1PPNA 1ZCMA 1MHWA 3N3GA 1A6RA 1KHPA 3RVVA 3M99A 2WBFX 1EWOA 4CZWA 1AU2A 4YYRA 2E00A 5FPWA 4PADA 1PBHA 1BY8A 4CDCB 1MS6A 4DMXA 3ERVA 2FT2A 1FH0A 5F02A 1KFUL 3OF9A 4YYWA 1AYVA 2FYEA 5CVOB 8PCHA 5EF4A 1BQIA 2Y5BA 1SNKA 1S4VA 3F75A 4BS6A 2DZYA 2G8JA 1F2AA 3KWZA 3U8EA 2O6XA 3BOWA 1DF0A 1GLOA 3N4CA 1CS8A 2CB5A 4WA6A 5K16A 2DC7A 1AU3A 4RY2A 4BQVA 4KLBA 1U5IA 2AS8A 2B1MA 2E01A 1PXVA 3QSDA 4FJCA 2AVWA 2DCBA 3IMAA 4QBBA 2DZZA 1ITOA 2OZ2A 3BC3A 1YALA 2P0RA 1PE6A 2E02A 1NB5A 2HXZA 2PNSA 2AUZA 2P7UA 1U9XA 2P86A 4YVAA 2OP3A 2YJ9A 3WXGA 3C9EA 5CVNB 3OVZA 2AYOA 1F29A 2XU4A 1ZIVA 4QH6A 4Q8HA 4Q8GA 2FTDA 3HHAA 3ZUAA 1CTEA 5JA7A 2DCDA 3MORA 9PAPA 2VHFA 1CB5A 1F2BA 3BPFA 1AIMA 3PNRA 3IHPA 1AYUA 4I05A 2R9FA 4X6HA 2C0YA 3O0UA 1AU0A 4YYQA 1AYWA 3HD3A 3MHSA 2GFOA 2DCCA 2PBHA 1CV8A 1TU6A 5CHTA 2FRQA 4P6EA 1F2CA 2FQ9A 2NQGA 3MHHA 2ATOA 3PW3A 1K3BB 2DC9A 1GECE 1AECA 3O1GA 4N8WA 2R9OA 1YT7A 1Y08A 4BPVA 3LXSA 4YYVA 4HWYA 4CDDB 2G8EA 1U9VA 1EWLA 1QMYA 3CH2X 5CHVA 5EGWA 1POPA 4BS5A 3MTNA 1NPZA 4FK5A 3KFQA 2E03A 1VSNA 3TNXA 2DJFB 3IOQA 2VHSA 2IPPB 3V6CA 1ICFA 5A24A 3QT4A 1MIRA 3KW9A 2BDLA 1YVBA 3HHIA 1Y4HA 3N3KA 3KKUA 3S3QA 4ZUXU 2DJGB 2GHUA 3USVA 1M6DA 2NQIA 3WXFA 3QJ3A 2B1NA 2CIOA 1YK8A 3E1ZB 1THEA 4W5CA 2NQDB 1TLOA 4I07A 4PI3A 3S3RA 2AU1A 3CBKA 4QRGA 4AXMA 1Q6KA 4MSXA 2ARYA 2AYNA 2JQGR 2NQAA 2FRAA 3D6SA 5PADA 1EF7A 3RVWA 2YJ2A 4CDEB 2HHNA 1GMYA 1PCIA 1X9YA 1SP4B 1KHQA 5J94A 1VJVA 3LFYA 1NB3A 2FO5A 2OULA 4N4ZA 3BCNA 1U9QX 1ATKA 3NHEA
chains in the Genus database with same CATH superfamily
3P5UA 3I06A 3AI8A 3H8CA 3K9MA 3KWBX 2BDZA 3F5VA 6PADA 4BSQA 3K8UA 4PT5A 3H89A 1MEGA 2IBIA 4AXLA 2BTWB 4YYSA 4G54A 3H6SA 4I04A 4BOSA 4W4UA 3BPMA 1PADA 2FUDA 2PREA 1KFXL 2HH5A 3H8BA 1DEUA 1DKIA 4MZOA 1CQDA 4QRXA 2Y6EA 1NQCA 2XU1A 4RF0A 4MI7A 1HUCB 2F7DA 1GCBA 1O0EA 2R9MA 4MZSA 4QRVA 4K7CA 4N79A 2DC6A 3PDFA 2G7YA 3HWNA 3TRKA 3I3TA 1PPPA 2JQFR 1MEMA 1IWDA 1ME3A 2H7JA 1ME4A 1U9WA 3IUTA 4WURA 1QOLA 1MDWA 4FIPA 4D8EA 1NLJA 4REZA 2R6NA 2R9NA 3RVXA 4IUMA 2DCAA 3DF0A 4ZTBA 2F1GA 3P5XA 4YYUA 2AUXA 2XU3A 3ZNHA 3PBHA 3OF8A 2DC8A 3GCBA 5CVMA 4PP2E 4YV8A 2YJ8A 7PCKA 1BP4A 4DMYA 1QDQA 3CH3X 2G6DA 4BOQA 2YJBA 1QXPA 4X6JA 4XUIA 4CDFB 1BGOA 2YJCA 3WXEA 3P5WA 5JH3A 1AU4A 3CBJA 3PT2A 2HD5A 4RKXA 1NL6A 3KSEA 3MP2A 4A5UA 3V6EA 5JZEA 1PPDA 5EZSA 2XU5A 3KX1A 3B79A 3IV2A 1CPJA 1CVZA 5KO3A 4XR7A 1CJLA 1YK7A 3OVXA 2R9CA 3K24A 1XKGA 3MJ5A 4OEMA 1PPOA 3IEJA 4PP1A 2AIMA 3H7DA 1TL9A 2ACTA 2PADA 1JQPA 3PSEA 4OVZB 1STFE 4P6GA 4W5BA 1PIPA 4BOUA 1CSBB 3P5VA 3BWKA 4X6IA 4OELA 3OISA 1EWPA 1KXRA 1EWMA 1PPNA 1ZCMA 1MHWA 2JRIA 3N3GA 3B21A 1A6RA 1KHPA 3RVVA 3M99A 2WBFX 1EWOA 4CZWA 1AU2A 4YYRA 3PRMA 2E00A 4MM3B 3W30A 5FPWA 3OQCA 4PADA 5EZQA 1PBHA 3BY4A 1UKFA 1BY8A 4CDCB 1MS6A 4DMXA 3C0RA 3ERVA 2FT2A 1FH0A 2FE8A 5F02A 1KFUL 3OF9A 4YYWA 1AYVA 2FYEA 5CVOB 3IFUA 8PCHA 3TMPA 5EF4A 1BQIA 2Y5BA 1SNKA 1S4VA 3F75A 4BS6A 4M0WA 2DZYA 2G8JA 1F2AA 4D8IA 3PRPA 3KWZA 3PHWA 3U8EA 5E6JA 2O6XA 3BOWA 1DF0A 1GLOA 3N4CA 1CS8A 2CB5A 4WA6A 5K16A 2DC7A 1AU3A 4RY2A 4BQVA 2J7QC 4KLBA 1U5IA 2AS8A 2B1MA 2E01A 1PXVA 3QSDA 4FJCA 2AVWA 2DCBA 3IMAA 4QBBA 2DZZA 1ITOA 2OZ2A 3BC3A 1YALA 2P0RA 1PE6A 2E02A 1PVJA 1NB5A 2HXZA 2PNSA 2AUZA 2P7UA 1U9XA 2P86A 4YVAA 2OP3A 4P16A 2YJ9A 2BU3A 3WXGA 3C9EA 5CVNB 3OVZA 2AYOA 1F29A 2XU4A 1ZIVA 4QH6A 4Q8HA 4Q8GA 2FTDA 3HHAA 2JTCA 3ZUAA 1CTEA 5JA7A 2DCDA 3MORA 9PAPA 4BOPA 2VHFA 1CB5A 1F2BA 3BPFA 1AIMA 3PNRA 3IHPA 1AYUA 2DOSA 4I05A 2R9FA 4X6HA 2C0YA 3O0UA 1AU0A 4D8BA 4YYQA 1AYWA 4BOZA 3HD3A 3MHSA 2GFOA 2DCCA 4HXDB 2PBHA 1CV8A 1TU6A 5CHTA 2FRQA 2BTWA 4P6EA 1F2CA 3O65A 2FQ9A 2NQGA 3MHHA 2ATOA 2Z84A 3PW3A 1K3BB 2DC9A 1GECE 1AECA 3BBAA 3O1GA 4RNAA 4N8WA 2R9OA 1YT7A 1Y08A 4BPVA 3LXSA 4YYVA 4R3DA 3BB7A 4HWYA 4CDDB 2G8EA 1U9VA 2HWKA 4XZXA 1EWLA 3PHUA 1QMYA 3CH2X 5CHVA 3MTVA 5EGWA 1YZBA 1POPA 4BS5A 3MTNA 1NPZA 4FK5A 4OW0A 3KFQA 2E03A 1VSNA 3TNXA 2DJFB 3IOQA 2VHSA 2IPPB 3V6CA 1ICFA 5A24A 3QT4A 1MIRA 3KW9A 2BDLA 1YVBA 3HHIA 1Y4HA 3N3KA 3KKUA 3S3QA 4ZUXU 2DJGB 4GUAA 2GHUA 3USVA 1M6DA 2NQIA 3WXFA 3RNVA 3QJ3A 2B1NA 2CIOA 3E9SA 1YK8A 3E1ZB 1THEA 4W5CA 2NQDB 1TLOA 4I07A 4PI3A 3S3RA 2AU1A 2J7QA 3CBKA 4QRGA 4AXMA 1Q6KA 4MSXA 2ARYA 2AYNA 2AGAA 2JQGR 2NQAA 2FRAA 3D6SA 5PADA 1EF7A 3RVWA 2UZJA 2YJ2A 4CDEB 2HHNA 1GMYA 3W31A 1PCIA 1X9YA 1SP4B 4RF1A 1KHQA 5J94A 1VJVA 3LFYA 1NB3A 2FO5A 4OVZA 4IP3A 2OULA 4N4ZA 3BCNA 3PHXA 1U9QX 1ATKA 3NHEA
chains in the Genus database with same CATH topology
3P5UA 3I06A 3AI8A 3H8CA 3K9MA 3KWBX 2BDZA 3F5VA 6PADA 4BSQA 3K8UA 3H89A 1MEGA 2IBIA 4AXLA 4YYSA 4G54A 3H6SA 4I04A 4W4UA 3BPMA 1PADA 2FUDA 2PREA 1KFXL 2HH5A 3H8BA 1DEUA 4MZOA 1CQDA 4QRXA 2Y6EA 1NQCA 2XU1A 1HUCB 2F7DA 1GCBA 1O0EA 2R9MA 4MZSA 4QRVA 4K7CA 4N79A 2DC6A 3PDFA 2G7YA 3HWNA 3I3TA 1PPPA 2JQFR 1MEMA 1IWDA 1ME3A 2H7JA 1ME4A 1U9WA 3IUTA 1QOLA 1MDWA 4FIPA 1NLJA 2R6NA 2R9NA 3RVXA 2DCAA 3DF0A 2F1GA 3P5XA 4YYUA 2AUXA 2XU3A 3PBHA 3OF8A 2DC8A 3GCBA 5CVMA 4PP2E 4YV8A 2YJ8A 7PCKA 1BP4A 4DMYA 1QDQA 3CH3X 2G6DA 2YJBA 1QXPA 4X6JA 4XUIA 4CDFB 1BGOA 2YJCA 3WXEA 3P5WA 5JH3A 1AU4A 3CBJA 2HD5A 1NL6A 3KSEA 3V6EA 1PPDA 2XU5A 3KX1A 3B79A 3IV2A 1CPJA 1CVZA 1W5RA 4XR7A 1CJLA 1YK7A 3OVXA 2R9CA 1W4TA 3K24A 1XKGA 4NV8A 4OEMA 1PPOA 3IEJA 4PP1A 2AIMA 3H7DA 1TL9A 2ACTA 2PADA 1JQPA 3D9WA 1STFE 4P6GA 4W5BA 1PIPA 1CSBB 3P5VA 3BWKA 4X6IA 4OELA 3OISA 1EWPA 1KXRA 1EWMA 1PPNA 1ZCMA 1MHWA 3N3GA 1A6RA 1KHPA 3RVVA 3M99A 4NV7A 2WBFX 1EWOA 4CZWA 1AU2A 4YYRA 2E00A 5FPWA 4PADA 1PBHA 1BY8A 4CDCB 1MS6A 4DMXA 3ERVA 2FT2A 1FH0A 5F02A 1KFUL 3OF9A 4YYWA 1AYVA 2FYEA 5CVOB 8PCHA 5EF4A 1BQIA 2Y5BA 1SNKA 1S4VA 3F75A 4BS6A 2DZYA 2G8JA 1F2AA 3KWZA 3U8EA 2O6XA 3BOWA 1DF0A 1GLOA 3N4CA 1CS8A 2CB5A 4WA6A 5K16A 2DC7A 1AU3A 4RY2A 4BQVA 4C5PA 4KLBA 1U5IA 2AS8A 2B1MA 2E01A 1PXVA 2VFCA 3QSDA 4FJCA 2AVWA 2DCBA 3IMAA 4QBBA 4BGFA 2DZZA 1ITOA 2OZ2A 3BC3A 1YALA 2P0RA 1PE6A 2E02A 1NB5A 2HXZA 2PNSA 2AUZA 2P7UA 1U9XA 2P86A 4YVAA 2OP3A 2YJ9A 3WXGA 3C9EA 5CVNB 3OVZA 2AYOA 1F29A 2XU4A 1ZIVA 4QH6A 4Q8HA 4Q8GA 2FTDA 3HHAA 3ZUAA 1CTEA 1E2TA 5JA7A 2DCDA 3MORA 9PAPA 2VHFA 1CB5A 1F2BA 3BPFA 1AIMA 3PNRA 3IHPA 1AYUA 4I05A 2R9FA 4X6HA 2C0YA 3O0UA 1AU0A 4YYQA 1AYWA 3HD3A 3MHSA 2GFOA 2DCCA 2PBHA 1CV8A 1TU6A 5CHTA 2FRQA 4P6EA 1F2CA 2FQ9A 2NQGA 3MHHA 2ATOA 3PW3A 1K3BB 1W6FA 2DC9A 1GECE 1AECA 3O1GA 4N8WA 2R9OA 1YT7A 1Y08A 4BPVA 3LXSA 4YYVA 2BSZA 4HWYA 4CDDB 2G8EA 1U9VA 1EWLA 1QMYA 3CH2X 5CHVA 1GX3A 5EGWA 1POPA 4BS5A 3MTNA 1NPZA 4FK5A 3KFQA 2E03A 1VSNA 3TNXA 2DJFB 3IOQA 2VHSA 2IPPB 3V6CA 1ICFA 5A24A 3QT4A 1MIRA 3KW9A 2BDLA 1YVBA 3HHIA 1Y4HA 3N3KA 3KKUA 3S3QA 4ZUXU 2DJGB 4B55A 2GHUA 3USVA 1M6DA 2NQIA 3WXFA 3QJ3A 2B1NA 2CIOA 1YK8A 3E1ZB 1THEA 4W5CA 2NQDB 1TLOA 4I07A 4PI3A 3S3RA 2AU1A 3CBKA 4GUZA 4QRGA 4AXMA 1Q6KA 4MSXA 2ARYA 2VFBA 2AYNA 2JQGR 3LTWA 2NQAA 2FRAA 3D6SA 5PADA 1EF7A 3RVWA 2YJ2A 4CDEB 2HHNA 1GMYA 1PCIA 1X9YA 1SP4B 1KHQA 5J94A 1VJVA 3LFYA 1NB3A 2FO5A 2OULA 4N4ZA 3BCNA 1U9QX 1ATKA 3NHEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P5U A;  3I06 A;  3AI8 A;  3H8C A;  3K9M A;  3KWB X;  2BDZ A;  3F5V A;  6PAD A;  4BSQ A;  3K8U A;  3H89 A;  1MEG A;  2IBI A;  4AXL A;  4YYS A;  4G54 A;  3H6S A;  4I04 A;  4W4U A;  3BPM A;  1PAD A;  2FUD A;  2PRE A;  1KFX L;  2HH5 A;  3H8B A;  1DEU A;  4MZO A;  1CQD A;  4QRX A;  2Y6E A;  1NQC A;  2XU1 A;  1HUC B;  2F7D A;  1GCB A;  1O0E A;  2R9M A;  4MZS A;  4QRV A;  4K7C A;  4N79 A;  2DC6 A;  3PDF A;  2G7Y A;  3HWN A;  3I3T A;  1PPP A;  2JQF R;  1MEM A;  1IWD A;  1ME3 A;  2H7J A;  1ME4 A;  1U9W A;  3IUT A;  1QOL A;  1MDW A;  4FIP A;  1NLJ A;  2R6N A;  2R9N A;  3RVX A;  2DCA A;  3DF0 A;  2F1G A;  3P5X A;  4YYU A;  2AUX A;  2XU3 A;  3PBH A;  3OF8 A;  2DC8 A;  3GCB A;  5CVM A;  4PP2 E;  4YV8 A;  2YJ8 A;  7PCK A;  1BP4 A;  4DMY A;  1QDQ A;  3CH3 X;  2G6D A;  2YJB A;  1QXP A;  4X6J A;  4XUI A;  4CDF B;  1BGO A;  2YJC A;  3WXE A;  3P5W A;  5JH3 A;  1AU4 A;  3CBJ A;  2HD5 A;  1NL6 A;  3KSE A;  3V6E A;  1PPD A;  2XU5 A;  3KX1 A;  3B79 A;  3IV2 A;  1CPJ A;  1CVZ A;  4XR7 A;  1CJL A;  1YK7 A;  3OVX A;  2R9C A;  3K24 A;  1XKG A;  4OEM A;  1PPO A;  3IEJ A;  4PP1 A;  2AIM A;  3H7D A;  1TL9 A;  2ACT A;  2PAD A;  1JQP A;  1STF E;  4P6G A;  4W5B A;  1PIP A;  1CSB B;  3P5V A;  3BWK A;  4X6I A;  4OEL A;  3OIS A;  1EWP A;  1KXR A;  1EWM A;  1PPN A;  1ZCM A;  1MHW A;  3N3G A;  1A6R A;  1KHP A;  3RVV A;  3M99 A;  2WBF X;  1EWO A;  4CZW A;  1AU2 A;  4YYR A;  2E00 A;  5FPW A;  4PAD A;  1PBH A;  1BY8 A;  4CDC B;  1MS6 A;  4DMX A;  3ERV A;  2FT2 A;  1FH0 A;  5F02 A;  1KFU L;  3OF9 A;  4YYW A;  1AYV A;  2FYE A;  5CVO B;  8PCH A;  5EF4 A;  1BQI A;  2Y5B A;  1SNK A;  1S4V A;  3F75 A;  4BS6 A;  2DZY A;  2G8J A;  1F2A A;  3KWZ A;  3U8E A;  2O6X A;  3BOW A;  1DF0 A;  1GLO A;  3N4C A;  1CS8 A;  2CB5 A;  4WA6 A;  5K16 A;  2DC7 A;  1AU3 A;  4RY2 A;  4BQV A;  4KLB A;  1U5I A;  2AS8 A;  2B1M A;  2E01 A;  1PXV A;  3QSD A;  4FJC A;  2AVW A;  2DCB A;  3IMA A;  4QBB A;  2DZZ A;  1ITO A;  2OZ2 A;  3BC3 A;  1YAL A;  2P0R A;  1PE6 A;  2E02 A;  1NB5 A;  2HXZ A;  2PNS A;  2AUZ A;  2P7U A;  1U9X A;  2P86 A;  4YVA A;  2OP3 A;  2YJ9 A;  3WXG A;  3C9E A;  5CVN B;  3OVZ A;  2AYO A;  1F29 A;  2XU4 A;  1ZIV A;  4QH6 A;  4Q8H A;  4Q8G A;  2FTD A;  3HHA A;  3ZUA A;  1CTE A;  5JA7 A;  2DCD A;  3MOR A;  9PAP A;  2VHF A;  1CB5 A;  1F2B A;  3BPF A;  1AIM A;  3PNR A;  3IHP A;  1AYU A;  4I05 A;  2R9F A;  4X6H A;  2C0Y A;  3O0U A;  1AU0 A;  4YYQ A;  1AYW A;  3HD3 A;  3MHS A;  2GFO A;  2DCC A;  2PBH A;  1CV8 A;  1TU6 A;  5CHT A;  2FRQ A;  4P6E A;  1F2C A;  2FQ9 A;  2NQG A;  3MHH A;  2ATO A;  3PW3 A;  1K3B B;  2DC9 A;  1GEC E;  1AEC A;  3O1G A;  4N8W A;  2R9O A;  1YT7 A;  1Y08 A;  4BPV A;  3LXS A;  4YYV A;  4HWY A;  4CDD B;  2G8E A;  1U9V A;  1EWL A;  1QMY A;  3CH2 X;  5CHV A;  5EGW A;  1POP A;  4BS5 A;  3MTN A;  1NPZ A;  4FK5 A;  3KFQ A;  2E03 A;  1VSN A;  3TNX A;  2DJF B;  3IOQ A;  2VHS A;  2IPP B;  3V6C A;  1ICF A;  5A24 A;  3QT4 A;  1MIR A;  3KW9 A;  2BDL A;  1YVB A;  3HHI A;  1Y4H A;  3N3K A;  3KKU A;  3S3Q A;  4ZUX U;  2DJG B;  2GHU A;  3USV A;  1M6D A;  2NQI A;  3WXF A;  3QJ3 A;  2B1N A;  2CIO A;  1YK8 A;  3E1Z B;  1THE A;  4W5C A;  2NQD B;  1TLO A;  4I07 A;  4PI3 A;  3S3R A;  2AU1 A;  3CBK A;  4QRG A;  4AXM A;  1Q6K A;  4MSX A;  2ARY A;  2AYN A;  2JQG R;  2NQA A;  2FRA A;  3D6S A;  5PAD A;  1EF7 A;  3RVW A;  2YJ2 A;  4CDE B;  2HHN A;  1GMY A;  1PCI A;  1X9Y A;  1SP4 B;  1KHQ A;  5J94 A;  1VJV A;  3LFY A;  1NB3 A;  2FO5 A;  2OUL A;  4N4Z A;  3BCN A;  1U9Q X;  1ATK A;  3NHE A; 
#chains in the Genus database with same CATH topology
 3P5U A;  3I06 A;  3AI8 A;  3H8C A;  3K9M A;  3KWB X;  2BDZ A;  3F5V A;  6PAD A;  4BSQ A;  3K8U A;  4PT5 A;  3H89 A;  1MEG A;  2IBI A;  4AXL A;  2BTW B;  4YYS A;  4G54 A;  3H6S A;  4I04 A;  4BOS A;  4W4U A;  3BPM A;  1PAD A;  2FUD A;  2PRE A;  1KFX L;  2HH5 A;  3H8B A;  1DEU A;  1DKI A;  4MZO A;  1CQD A;  4QRX A;  2Y6E A;  1NQC A;  2XU1 A;  4RF0 A;  4MI7 A;  1HUC B;  2F7D A;  1GCB A;  1O0E A;  2R9M A;  4MZS A;  4QRV A;  4K7C A;  4N79 A;  2DC6 A;  3PDF A;  2G7Y A;  3HWN A;  3TRK A;  3I3T A;  1PPP A;  2JQF R;  1MEM A;  1IWD A;  1ME3 A;  2H7J A;  1ME4 A;  1U9W A;  3IUT A;  4WUR A;  1QOL A;  1MDW A;  4FIP A;  4D8E A;  1NLJ A;  4REZ A;  2R6N A;  2R9N A;  3RVX A;  4IUM A;  2DCA A;  3DF0 A;  4ZTB A;  2F1G A;  3P5X A;  4YYU A;  2AUX A;  2XU3 A;  3ZNH A;  3PBH A;  3OF8 A;  2DC8 A;  3GCB A;  5CVM A;  4PP2 E;  4YV8 A;  2YJ8 A;  7PCK A;  1BP4 A;  4DMY A;  1QDQ A;  3CH3 X;  2G6D A;  4BOQ A;  2YJB A;  1QXP A;  4X6J A;  4XUI A;  4CDF B;  1BGO A;  2YJC A;  3WXE A;  3P5W A;  5JH3 A;  1AU4 A;  3CBJ A;  3PT2 A;  2HD5 A;  4RKX A;  1NL6 A;  3KSE A;  3MP2 A;  4A5U A;  3V6E A;  5JZE A;  1PPD A;  5EZS A;  2XU5 A;  3KX1 A;  3B79 A;  3IV2 A;  1CPJ A;  1CVZ A;  5KO3 A;  4XR7 A;  1CJL A;  1YK7 A;  3OVX A;  2R9C A;  3K24 A;  1XKG A;  3MJ5 A;  4OEM A;  1PPO A;  3IEJ A;  4PP1 A;  2AIM A;  3H7D A;  1TL9 A;  2ACT A;  2PAD A;  1JQP A;  3PSE A;  4OVZ B;  1STF E;  4P6G A;  4W5B A;  1PIP A;  4BOU A;  1CSB B;  3P5V A;  3BWK A;  4X6I A;  4OEL A;  3OIS A;  1EWP A;  1KXR A;  1EWM A;  1PPN A;  1ZCM A;  1MHW A;  2JRI A;  3N3G A;  3B21 A;  1A6R A;  1KHP A;  3RVV A;  3M99 A;  2WBF X;  1EWO A;  4CZW A;  1AU2 A;  4YYR A;  3PRM A;  2E00 A;  4MM3 B;  3W30 A;  5FPW A;  3OQC A;  4PAD A;  5EZQ A;  1PBH A;  3BY4 A;  1UKF A;  1BY8 A;  4CDC B;  1MS6 A;  4DMX A;  3C0R A;  3ERV A;  2FT2 A;  1FH0 A;  2FE8 A;  5F02 A;  1KFU L;  3OF9 A;  4YYW A;  1AYV A;  2FYE A;  5CVO B;  3IFU A;  8PCH A;  3TMP A;  5EF4 A;  1BQI A;  2Y5B A;  1SNK A;  1S4V A;  3F75 A;  4BS6 A;  4M0W A;  2DZY A;  2G8J A;  1F2A A;  4D8I A;  3PRP A;  3KWZ A;  3PHW A;  3U8E A;  5E6J A;  2O6X A;  3BOW A;  1DF0 A;  1GLO A;  3N4C A;  1CS8 A;  2CB5 A;  4WA6 A;  5K16 A;  2DC7 A;  1AU3 A;  4RY2 A;  4BQV A;  2J7Q C;  4KLB A;  1U5I A;  2AS8 A;  2B1M A;  2E01 A;  1PXV A;  3QSD A;  4FJC A;  2AVW A;  2DCB A;  3IMA A;  4QBB A;  2DZZ A;  1ITO A;  2OZ2 A;  3BC3 A;  1YAL A;  2P0R A;  1PE6 A;  2E02 A;  1PVJ A;  1NB5 A;  2HXZ A;  2PNS A;  2AUZ A;  2P7U A;  1U9X A;  2P86 A;  4YVA A;  2OP3 A;  4P16 A;  2YJ9 A;  2BU3 A;  3WXG A;  3C9E A;  5CVN B;  3OVZ A;  2AYO A;  1F29 A;  2XU4 A;  1ZIV A;  4QH6 A;  4Q8H A;  4Q8G A;  2FTD A;  3HHA A;  2JTC A;  3ZUA A;  1CTE A;  5JA7 A;  2DCD A;  3MOR A;  9PAP A;  4BOP A;  2VHF A;  1CB5 A;  1F2B A;  3BPF A;  1AIM A;  3PNR A;  3IHP A;  1AYU A;  2DOS A;  4I05 A;  2R9F A;  4X6H A;  2C0Y A;  3O0U A;  1AU0 A;  4D8B A;  4YYQ A;  1AYW A;  4BOZ A;  3HD3 A;  3MHS A;  2GFO A;  2DCC A;  4HXD B;  2PBH A;  1CV8 A;  1TU6 A;  5CHT A;  2FRQ A;  2BTW A;  4P6E A;  1F2C A;  3O65 A;  2FQ9 A;  2NQG A;  3MHH A;  2ATO A;  2Z84 A;  3PW3 A;  1K3B B;  2DC9 A;  1GEC E;  1AEC A;  3BBA A;  3O1G A;  4RNA A;  4N8W A;  2R9O A;  1YT7 A;  1Y08 A;  4BPV A;  3LXS A;  4YYV A;  4R3D A;  3BB7 A;  4HWY A;  4CDD B;  2G8E A;  1U9V A;  2HWK A;  4XZX A;  1EWL A;  3PHU A;  1QMY A;  3CH2 X;  5CHV A;  3MTV A;  5EGW A;  1YZB A;  1POP A;  4BS5 A;  3MTN A;  1NPZ A;  4FK5 A;  4OW0 A;  3KFQ A;  2E03 A;  1VSN A;  3TNX A;  2DJF B;  3IOQ A;  2VHS A;  2IPP B;  3V6C A;  1ICF A;  5A24 A;  3QT4 A;  1MIR A;  3KW9 A;  2BDL A;  1YVB A;  3HHI A;  1Y4H A;  3N3K A;  3KKU A;  3S3Q A;  4ZUX U;  2DJG B;  4GUA A;  2GHU A;  3USV A;  1M6D A;  2NQI A;  3WXF A;  3RNV A;  3QJ3 A;  2B1N A;  2CIO A;  3E9S A;  1YK8 A;  3E1Z B;  1THE A;  4W5C A;  2NQD B;  1TLO A;  4I07 A;  4PI3 A;  3S3R A;  2AU1 A;  2J7Q A;  3CBK A;  4QRG A;  4AXM A;  1Q6K A;  4MSX A;  2ARY A;  2AYN A;  2AGA A;  2JQG R;  2NQA A;  2FRA A;  3D6S A;  5PAD A;  1EF7 A;  3RVW A;  2UZJ A;  2YJ2 A;  4CDE B;  2HHN A;  1GMY A;  3W31 A;  1PCI A;  1X9Y A;  1SP4 B;  4RF1 A;  1KHQ A;  5J94 A;  1VJV A;  3LFY A;  1NB3 A;  2FO5 A;  4OVZ A;  4IP3 A;  2OUL A;  4N4Z A;  3BCN A;  3PHX A;  1U9Q X;  1ATK A;  3NHE A; 
#chains in the Genus database with same CATH homology
 3P5U A;  3I06 A;  3AI8 A;  3H8C A;  3K9M A;  3KWB X;  2BDZ A;  3F5V A;  6PAD A;  4BSQ A;  3K8U A;  3H89 A;  1MEG A;  2IBI A;  4AXL A;  4YYS A;  4G54 A;  3H6S A;  4I04 A;  4W4U A;  3BPM A;  1PAD A;  2FUD A;  2PRE A;  1KFX L;  2HH5 A;  3H8B A;  1DEU A;  4MZO A;  1CQD A;  4QRX A;  2Y6E A;  1NQC A;  2XU1 A;  1HUC B;  2F7D A;  1GCB A;  1O0E A;  2R9M A;  4MZS A;  4QRV A;  4K7C A;  4N79 A;  2DC6 A;  3PDF A;  2G7Y A;  3HWN A;  3I3T A;  1PPP A;  2JQF R;  1MEM A;  1IWD A;  1ME3 A;  2H7J A;  1ME4 A;  1U9W A;  3IUT A;  1QOL A;  1MDW A;  4FIP A;  1NLJ A;  2R6N A;  2R9N A;  3RVX A;  2DCA A;  3DF0 A;  2F1G A;  3P5X A;  4YYU A;  2AUX A;  2XU3 A;  3PBH A;  3OF8 A;  2DC8 A;  3GCB A;  5CVM A;  4PP2 E;  4YV8 A;  2YJ8 A;  7PCK A;  1BP4 A;  4DMY A;  1QDQ A;  3CH3 X;  2G6D A;  2YJB A;  1QXP A;  4X6J A;  4XUI A;  4CDF B;  1BGO A;  2YJC A;  3WXE A;  3P5W A;  5JH3 A;  1AU4 A;  3CBJ A;  2HD5 A;  1NL6 A;  3KSE A;  3V6E A;  1PPD A;  2XU5 A;  3KX1 A;  3B79 A;  3IV2 A;  1CPJ A;  1CVZ A;  1W5R A;  4XR7 A;  1CJL A;  1YK7 A;  3OVX A;  2R9C A;  1W4T A;  3K24 A;  1XKG A;  4NV8 A;  4OEM A;  1PPO A;  3IEJ A;  4PP1 A;  2AIM A;  3H7D A;  1TL9 A;  2ACT A;  2PAD A;  1JQP A;  3D9W A;  1STF E;  4P6G A;  4W5B A;  1PIP A;  1CSB B;  3P5V A;  3BWK A;  4X6I A;  4OEL A;  3OIS A;  1EWP A;  1KXR A;  1EWM A;  1PPN A;  1ZCM A;  1MHW A;  3N3G A;  1A6R A;  1KHP A;  3RVV A;  3M99 A;  4NV7 A;  2WBF X;  1EWO A;  4CZW A;  1AU2 A;  4YYR A;  2E00 A;  5FPW A;  4PAD A;  1PBH A;  1BY8 A;  4CDC B;  1MS6 A;  4DMX A;  3ERV A;  2FT2 A;  1FH0 A;  5F02 A;  1KFU L;  3OF9 A;  4YYW A;  1AYV A;  2FYE A;  5CVO B;  8PCH A;  5EF4 A;  1BQI A;  2Y5B A;  1SNK A;  1S4V A;  3F75 A;  4BS6 A;  2DZY A;  2G8J A;  1F2A A;  3KWZ A;  3U8E A;  2O6X A;  3BOW A;  1DF0 A;  1GLO A;  3N4C A;  1CS8 A;  2CB5 A;  4WA6 A;  5K16 A;  2DC7 A;  1AU3 A;  4RY2 A;  4BQV A;  4C5P A;  4KLB A;  1U5I A;  2AS8 A;  2B1M A;  2E01 A;  1PXV A;  2VFC A;  3QSD A;  4FJC A;  2AVW A;  2DCB A;  3IMA A;  4QBB A;  4BGF A;  2DZZ A;  1ITO A;  2OZ2 A;  3BC3 A;  1YAL A;  2P0R A;  1PE6 A;  2E02 A;  1NB5 A;  2HXZ A;  2PNS A;  2AUZ A;  2P7U A;  1U9X A;  2P86 A;  4YVA A;  2OP3 A;  2YJ9 A;  3WXG A;  3C9E A;  5CVN B;  3OVZ A;  2AYO A;  1F29 A;  2XU4 A;  1ZIV A;  4QH6 A;  4Q8H A;  4Q8G A;  2FTD A;  3HHA A;  3ZUA A;  1CTE A;  1E2T A;  5JA7 A;  2DCD A;  3MOR A;  9PAP A;  2VHF A;  1CB5 A;  1F2B A;  3BPF A;  1AIM A;  3PNR A;  3IHP A;  1AYU A;  4I05 A;  2R9F A;  4X6H A;  2C0Y A;  3O0U A;  1AU0 A;  4YYQ A;  1AYW A;  3HD3 A;  3MHS A;  2GFO A;  2DCC A;  2PBH A;  1CV8 A;  1TU6 A;  5CHT A;  2FRQ A;  4P6E A;  1F2C A;  2FQ9 A;  2NQG A;  3MHH A;  2ATO A;  3PW3 A;  1K3B B;  1W6F A;  2DC9 A;  1GEC E;  1AEC A;  3O1G A;  4N8W A;  2R9O A;  1YT7 A;  1Y08 A;  4BPV A;  3LXS A;  4YYV A;  2BSZ A;  4HWY A;  4CDD B;  2G8E A;  1U9V A;  1EWL A;  1QMY A;  3CH2 X;  5CHV A;  1GX3 A;  5EGW A;  1POP A;  4BS5 A;  3MTN A;  1NPZ A;  4FK5 A;  3KFQ A;  2E03 A;  1VSN A;  3TNX A;  2DJF B;  3IOQ A;  2VHS A;  2IPP B;  3V6C A;  1ICF A;  5A24 A;  3QT4 A;  1MIR A;  3KW9 A;  2BDL A;  1YVB A;  3HHI A;  1Y4H A;  3N3K A;  3KKU A;  3S3Q A;  4ZUX U;  2DJG B;  4B55 A;  2GHU A;  3USV A;  1M6D A;  2NQI A;  3WXF A;  3QJ3 A;  2B1N A;  2CIO A;  1YK8 A;  3E1Z B;  1THE A;  4W5C A;  2NQD B;  1TLO A;  4I07 A;  4PI3 A;  3S3R A;  2AU1 A;  3CBK A;  4GUZ A;  4QRG A;  4AXM A;  1Q6K A;  4MSX A;  2ARY A;  2VFB A;  2AYN A;  2JQG R;  3LTW A;  2NQA A;  2FRA A;  3D6S A;  5PAD A;  1EF7 A;  3RVW A;  2YJ2 A;  4CDE B;  2HHN A;  1GMY A;  1PCI A;  1X9Y A;  1SP4 B;  1KHQ A;  5J94 A;  1VJV A;  3LFY A;  1NB3 A;  2FO5 A;  2OUL A;  4N4Z A;  3BCN A;  1U9Q X;  1ATK A;  3NHE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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