4CDDB

Human dpp1 in complex with (2s)-n-((1s)-1-cyano-2-(4-(4-cyanophenyl) phenyl)ethyl)piperidine-2-carboxamide
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
162
structure length
162
Chain Sequence
HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHHT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords DIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN
total genus 42
structure length 162
sequence length 162
chains with identical sequence E
ec nomenclature ec 3.4.14.1: Dipeptidyl-peptidase I.
pdb deposition date 2013-10-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4cddB01
3V6CA 2DJGB 1TLOA 1PPOA 4PI3A 1Y08A 1AU4A 2FUDA 3IV2A 4Q8HA 2F7DA 3WXFA 4MZOA 1ZIVA 3PW3A 2DZZA 2FRAA 3N3KA 2B1NA 2XU1A 1THEA 2HXZA 1BY8A 2DC8A 3H8BA 4OEMA 4YVAA 3AI8A 4ZUXU 4P6GA 2G8JA 1CB5A 1TL9A 1NLJA 4BPVA 3KW9A 4P6EA 1JQPA 2HHNA 4W4UA 1S4VA 2OZ2A 3V6EA 1PBHA 1SP4B 1Y4HA 1PADA 1U9WA 3B79A 1NB3A 1A6RA 4X6HA 4X6JA 3WXGA 1AU2A 1BGOA 1MDWA 2R9MA 3PDFA 3BWKA 1M6DA 2C0YA 3KFQA 5JA7A 2HH5A 2P86A 4XUIA 2GFOA 3F5VA 2DCCA 4HWYA 2IPPB 1AU3A 3K9MA 2E00A 1X9YA 2WBFX 5J94A 1VSNA 2PADA 1ME3A 1MEGA 3K8UA 1CV8A 1POPA 5CVNB 2G6DA 3BC3A 4WA6A 2XU5A 1PIPA 3ERVA 2VHSA 1DF0A 1YALA 5A24A 1FH0A 4YYUA 2AYOA 3KWZA 2IBIA 1AU0A 4YYVA 1NB5A 3MTNA 2Y5BA 1MHWA 3ZUAA 2PBHA 2CIOA 4MZSA 1K3BB 4G54A 1PPPA 4PP1A 2PREA 3U8EA 2YJ9A 4MSXA 4W5CA 4YYQA 3P5WA 3OF9A 2FYEA 1F29A 2ARYA 4I05A 2P0RA 3USVA 4QH6A 3WXEA 1ITOA 3OF8A 1F2AA 4QRVA 2AS8A 1KFUL 3LFYA 1YVBA 2GHUA 4YYWA 1QDQA 4FJCA 4YV8A 2XU4A 2HD5A 2F1GA 2VHFA 1KFXL 1MS6A 3C9EA 2AVWA 3KX1A 1MEMA 2R9CA 4XR7A 4BS6A 4X6IA 4QRXA 3I06A 1CPJA 2BDZA 5EF4A 3RVVA 3K24A 3H8CA 1PCIA 2NQAA 1CTEA 3GCBA 1SNKA 3IMAA 3RVWA 5PADA 3QJ3A 4Q8GA 3BCNA 3RVXA 4W5BA 2FTDA 1GLOA 1CS8A 2E01A 3QT4A 3OVXA 2FO5A 3S3RA 2DCDA 1NL6A 2ACTA 4QBBA 5CVOB 1GECE 2FRQA 1YK8A 3IHPA 1AECA 1KXRA 1STFE 2YJ8A 1CVZA 4N8WA 2DZYA 3O0UA 2PNSA 2DC7A 3BPMA 3MORA 1ME4A 3PNRA 1DEUA 2FT2A 2AUXA 1QMYA 3H6SA 4YYRA 3P5VA 3I3TA 2B1MA 3NHEA 2DC9A 4BS5A 4CDDB 1MIRA 2NQGA 5CVMA 1BQIA 2YJBA 3H89A 3MHHA 3M99A 3LXSA 1U9QX 3HHAA 2XU3A 1QOLA 3N3GA 3HHIA 3HD3A 1ATKA 1PPNA 1EWMA 2AIMA 3D6SA 2JQGR 2FQ9A 2H7JA 3CH2X 1HUCB 3CBKA 5CHVA 2G8EA 2OULA 3S3QA 1AYVA 1BP4A 1U9XA 5EGWA 2DC6A 3IUTA 4PP2E 4CDFB 3IEJA 3KKUA 4N4ZA 4OELA 1PPDA 5CHTA 1GMYA 2YJCA 3DF0A 4YYSA 3P5UA 2R9OA 1QXPA 3CBJA 2BDLA 3N4CA 2AUZA 1KHQA 1Q6KA 8PCHA 3O1GA 3CH3X 1XKGA 4PADA 4KLBA 3TNXA 1AYUA 2ATOA 2O6XA 2CB5A 1YT7A 4BSQA 1PE6A 3H7DA 2NQIA 2R9FA 1F2BA 4CDEB 1CQDA 3HWNA 4RY2A 3E1ZB 2YJ2A 1VJVA 4BQVA 9PAPA 4K7CA 1ICFA 1NQCA 4I07A 3QSDA 1CSBB 2P7UA 1NPZA 4CZWA 1AIMA 2R9NA 6PADA 2DJFB 1O0EA 3OVZA 3BOWA 1CJLA 1TU6A 3PBHA 4AXMA 5F02A 2DCBA 1EF7A 1YK7A 1EWPA 4DMYA 1ZCMA 2AU1A 5FPWA 2DCAA 3KWBX 3OISA 1EWOA 5K16A 1PXVA 1U9VA 2NQDB 4FIPA 3MHSA 4AXLA 4I04A 3BPFA 4CDCB 4DMXA 1GCBA 1IWDA 4QRGA 1KHPA 2R6NA 2JQFR 2Y6EA 7PCKA 1AYWA 1EWLA 2OP3A 1F2CA 2G7YA 4FK5A 3P5XA 3F75A 2AYNA 2E02A 3IOQA 5JH3A 3KSEA 1U5IA 2E03A 4N79A
chains in the Genus database with same CATH superfamily
3V6CA 2DJGB 3PRPA 3PHXA 4A5UA 1TLOA 1PPOA 4P16A 4BOPA 4PI3A 1Y08A 1AU4A 2FUDA 3IV2A 2HWKA 3MP2A 4Q8HA 3PSEA 2F7DA 3WXFA 4RKXA 4HXDB 4MZOA 1ZIVA 3PW3A 2DZZA 2FRAA 3N3KA 2B1NA 2XU1A 1THEA 2HXZA 1BY8A 2DC8A 3H8BA 4OEMA 4YVAA 3AI8A 3IFUA 4ZUXU 4P6GA 2G8JA 1CB5A 1TL9A 1NLJA 4BPVA 3KW9A 4P6EA 1JQPA 2HHNA 4W4UA 1S4VA 2OZ2A 3V6EA 1PBHA 1SP4B 1Y4HA 1PADA 3OQCA 3MTVA 1U9WA 2J7QA 3B79A 3W31A 1NB3A 3PHWA 1A6RA 4X6HA 4RF0A 4X6JA 3WXGA 2JTCA 1AU2A 2UZJA 1BGOA 3BB7A 1MDWA 2R9MA 3PDFA 2JRIA 3BWKA 4RF1A 3W30A 1M6DA 2C0YA 3KFQA 5JA7A 2HH5A 2P86A 4XUIA 2GFOA 3F5VA 2DCCA 4HWYA 2IPPB 1AU3A 3K9MA 2E00A 1X9YA 2WBFX 5J94A 1VSNA 3ZNHA 2PADA 1ME3A 1MEGA 3K8UA 1CV8A 4BOSA 2J7QC 1POPA 5CVNB 2G6DA 3BC3A 4WA6A 2XU5A 1PIPA 3ERVA 2VHSA 5JZEA 1DF0A 1YALA 4D8IA 4IP3A 5A24A 1FH0A 4YYUA 2AYOA 3KWZA 2IBIA 1AU0A 4YYVA 1NB5A 5KO3A 3MTNA 2Y5BA 1MHWA 3ZUAA 2PBHA 3BBAA 2CIOA 4MZSA 1K3BB 4G54A 1PPPA 4PP1A 2PREA 3U8EA 2YJ9A 4MSXA 4W5CA 4YYQA 3P5WA 3OF9A 3TMPA 2FYEA 1F29A 2ARYA 4I05A 2P0RA 3USVA 4QH6A 3WXEA 1ITOA 3OF8A 1F2AA 4QRVA 2AS8A 1KFUL 3LFYA 1YVBA 4D8EA 2GHUA 4IUMA 4BOUA 1QDQA 4YYWA 4FJCA 4YV8A 4OW0A 2XU4A 2HD5A 2F1GA 2VHFA 1KFXL 1MS6A 3C9EA 2AVWA 3KX1A 1MEMA 4OVZB 4ZTBA 2R9CA 4XR7A 2DOSA 4BS6A 4X6IA 4QRXA 3I06A 2BTWA 1CPJA 2BDZA 5EF4A 3RVVA 3K24A 3H8CA 1PCIA 1DKIA 3TRKA 2NQAA 1CTEA 3GCBA 1SNKA 3IMAA 3RVWA 5PADA 3QJ3A 3PHUA 3BCNA 4Q8GA 3RVXA 4W5BA 2FE8A 2FTDA 1GLOA 1CS8A 2E01A 3QT4A 3C0RA 3OVXA 2FO5A 3S3RA 2DCDA 1NL6A 2ACTA 4MM3B 4QBBA 5CVOB 1GECE 2FRQA 1YK8A 3IHPA 1AECA 1KXRA 1STFE 2YJ8A 1CVZA 4N8WA 2DZYA 3O0UA 2PNSA 2DC7A 3BPMA 3MORA 1ME4A 3PNRA 1DEUA 2FT2A 2AUXA 1QMYA 3E9SA 3H6SA 4YYRA 3P5VA 3I3TA 2B1MA 4R3DA 3NHEA 2DC9A 4BS5A 4CDDB 1MIRA 2NQGA 5EZSA 5CVMA 1BQIA 2YJBA 3H89A 3MHHA 3M99A 3LXSA 1U9QX 3HHAA 2XU3A 1QOLA 3N3GA 3HHIA 3HD3A 1ATKA 1PPNA 1EWMA 2AIMA 3D6SA 5EZQA 2JQGR 2FQ9A 2H7JA 3CH2X 1HUCB 3MJ5A 3CBKA 5CHVA 2G8EA 2OULA 3S3QA 1AYVA 1BP4A 1U9XA 4XZXA 5EGWA 2DC6A 3IUTA 4PP2E 4CDFB 3IEJA 3KKUA 5E6JA 4N4ZA 4WURA 4PT5A 4OELA 1PPDA 5CHTA 1GMYA 2YJCA 3DF0A 4YYSA 3P5UA 2R9OA 1QXPA 3CBJA 2BDLA 3B21A 4D8BA 3N4CA 2BTWB 2AUZA 1KHQA 1Q6KA 8PCHA 3O1GA 3CH3X 3O65A 1XKGA 4PADA 4KLBA 3TNXA 1AYUA 2ATOA 2O6XA 2BU3A 1YZBA 2CB5A 1YT7A 4BSQA 1PE6A 3H7DA 2NQIA 2R9FA 1F2BA 4CDEB 1CQDA 3HWNA 4RY2A 3E1ZB 2YJ2A 4OVZA 1VJVA 4BQVA 9PAPA 4K7CA 1ICFA 1NQCA 4I07A 3QSDA 4RNAA 1CSBB 1UKFA 2P7UA 1NPZA 4CZWA 1AIMA 3PRMA 2R9NA 6PADA 2DJFB 1O0EA 3OVZA 3BY4A 3BOWA 1CJLA 1TU6A 3PBHA 4AXMA 5F02A 2DCBA 1EF7A 1PVJA 1YK7A 4GUAA 4BOQA 1EWPA 3RNVA 4DMYA 4BOZA 4MI7A 1ZCMA 2AU1A 5FPWA 2DCAA 3KWBX 3OISA 1EWOA 5K16A 1PXVA 1U9VA 2NQDB 4FIPA 3MHSA 2Z84A 4AXLA 4I04A 3BPFA 4CDCB 4M0WA 4REZA 4DMXA 3PT2A 1GCBA 1IWDA 4QRGA 1KHPA 2R6NA 2JQFR 2Y6EA 7PCKA 1AYWA 1EWLA 2OP3A 1F2CA 2AGAA 2G7YA 4FK5A 3P5XA 3F75A 2AYNA 2E02A 3IOQA 5JH3A 3KSEA 1U5IA 2E03A 4N79A
chains in the Genus database with same CATH topology
3V6CA 2DJGB 1TLOA 1PPOA 4PI3A 1Y08A 1AU4A 2FUDA 3IV2A 4Q8HA 2F7DA 3WXFA 4MZOA 1ZIVA 3PW3A 2DZZA 2FRAA 3N3KA 2B1NA 2XU1A 1THEA 2HXZA 1BY8A 2DC8A 3H8BA 4OEMA 4YVAA 1W6FA 3AI8A 4ZUXU 4P6GA 2G8JA 1CB5A 1TL9A 1NLJA 4BPVA 3KW9A 4P6EA 1JQPA 2HHNA 4W4UA 1S4VA 2OZ2A 3V6EA 1PBHA 1SP4B 1Y4HA 1PADA 1U9WA 3B79A 1NB3A 1A6RA 4X6HA 4X6JA 3WXGA 1AU2A 1BGOA 1MDWA 2R9MA 3PDFA 3BWKA 1M6DA 2C0YA 3KFQA 5JA7A 2HH5A 2P86A 4XUIA 4NV8A 2GFOA 3F5VA 2DCCA 4HWYA 2IPPB 1AU3A 3K9MA 2E00A 1X9YA 2WBFX 5J94A 1VSNA 2PADA 1ME3A 1MEGA 3K8UA 1CV8A 1POPA 5CVNB 2G6DA 3BC3A 4WA6A 2XU5A 1PIPA 3ERVA 2VHSA 1DF0A 1YALA 5A24A 1FH0A 4YYUA 2VFCA 2AYOA 3KWZA 2IBIA 1AU0A 4YYVA 1NB5A 3MTNA 2Y5BA 1MHWA 3ZUAA 2PBHA 2CIOA 4MZSA 1K3BB 4G54A 1PPPA 4PP1A 2PREA 3U8EA 2YJ9A 4MSXA 4W5CA 4YYQA 3P5WA 3D9WA 3OF9A 2FYEA 1F29A 2ARYA 4I05A 2P0RA 3USVA 4GUZA 4QH6A 3WXEA 1ITOA 3OF8A 1F2AA 4QRVA 2AS8A 1KFUL 3LFYA 1YVBA 2GHUA 4YYWA 1QDQA 4FJCA 4YV8A 2XU4A 2HD5A 2F1GA 2VHFA 1KFXL 1MS6A 3C9EA 2AVWA 3KX1A 1MEMA 2R9CA 4XR7A 4BS6A 4X6IA 4QRXA 3I06A 1CPJA 2BDZA 5EF4A 3RVVA 3K24A 3H8CA 1PCIA 2NQAA 1CTEA 3GCBA 1SNKA 3IMAA 3RVWA 5PADA 3QJ3A 4Q8GA 3BCNA 3RVXA 1GX3A 4W5BA 2FTDA 1GLOA 1CS8A 2E01A 3QT4A 2VFBA 3OVXA 2FO5A 3S3RA 2DCDA 1NL6A 2ACTA 4QBBA 5CVOB 1GECE 2FRQA 1YK8A 3IHPA 1AECA 1KXRA 1STFE 2YJ8A 1CVZA 4N8WA 2DZYA 3LTWA 3O0UA 2PNSA 2DC7A 3BPMA 3MORA 1ME4A 3PNRA 1DEUA 2FT2A 2AUXA 1QMYA 3H6SA 4YYRA 3P5VA 3I3TA 2B1MA 3NHEA 2DC9A 4BS5A 4CDDB 1MIRA 2NQGA 5CVMA 1BQIA 2YJBA 3H89A 3MHHA 3M99A 1W4TA 3LXSA 1U9QX 4NV7A 3HHAA 2XU3A 1QOLA 3N3GA 4BGFA 3HHIA 4B55A 3HD3A 1ATKA 1PPNA 1EWMA 2AIMA 3D6SA 2JQGR 2FQ9A 2H7JA 3CH2X 1HUCB 3CBKA 1W5RA 5CHVA 2G8EA 2OULA 3S3QA 1AYVA 1BP4A 1U9XA 5EGWA 2DC6A 3IUTA 4PP2E 4CDFB 3IEJA 3KKUA 4N4ZA 4OELA 1PPDA 2BSZA 5CHTA 1GMYA 2YJCA 3DF0A 4YYSA 3P5UA 2R9OA 1QXPA 3CBJA 2BDLA 3N4CA 2AUZA 1KHQA 1Q6KA 8PCHA 3O1GA 3CH3X 1XKGA 4PADA 4KLBA 3TNXA 1AYUA 2ATOA 2O6XA 2CB5A 1YT7A 4BSQA 1PE6A 3H7DA 2NQIA 2R9FA 1F2BA 4CDEB 1CQDA 3HWNA 4RY2A 3E1ZB 2YJ2A 1VJVA 4BQVA 9PAPA 4K7CA 1ICFA 1NQCA 4I07A 3QSDA 1CSBB 2P7UA 1NPZA 4CZWA 1AIMA 2R9NA 6PADA 2DJFB 1O0EA 3OVZA 3BOWA 1CJLA 1TU6A 3PBHA 4AXMA 5F02A 2DCBA 1EF7A 1YK7A 1EWPA 4DMYA 1ZCMA 2AU1A 5FPWA 2DCAA 3KWBX 3OISA 1EWOA 5K16A 1PXVA 1U9VA 2NQDB 4FIPA 3MHSA 4AXLA 4I04A 3BPFA 4CDCB 4DMXA 1GCBA 1IWDA 4QRGA 1KHPA 2R6NA 2JQFR 2Y6EA 7PCKA 1AYWA 1EWLA 2OP3A 1E2TA 1F2CA 2G7YA 4FK5A 3P5XA 3F75A 2AYNA 2E02A 3IOQA 5JH3A 3KSEA 4C5PA 1U5IA 2E03A 4N79A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V6C A;  2DJG B;  1TLO A;  1PPO A;  4PI3 A;  1Y08 A;  1AU4 A;  2FUD A;  3IV2 A;  4Q8H A;  2F7D A;  3WXF A;  4MZO A;  1ZIV A;  3PW3 A;  2DZZ A;  2FRA A;  3N3K A;  2B1N A;  2XU1 A;  1THE A;  2HXZ A;  1BY8 A;  2DC8 A;  3H8B A;  4OEM A;  4YVA A;  3AI8 A;  4ZUX U;  4P6G A;  2G8J A;  1CB5 A;  1TL9 A;  1NLJ A;  4BPV A;  3KW9 A;  4P6E A;  1JQP A;  2HHN A;  4W4U A;  1S4V A;  2OZ2 A;  3V6E A;  1PBH A;  1SP4 B;  1Y4H A;  1PAD A;  1U9W A;  3B79 A;  1NB3 A;  1A6R A;  4X6H A;  4X6J A;  3WXG A;  1AU2 A;  1BGO A;  1MDW A;  2R9M A;  3PDF A;  3BWK A;  1M6D A;  2C0Y A;  3KFQ A;  5JA7 A;  2HH5 A;  2P86 A;  4XUI A;  2GFO A;  3F5V A;  2DCC A;  4HWY A;  2IPP B;  1AU3 A;  3K9M A;  2E00 A;  1X9Y A;  2WBF X;  5J94 A;  1VSN A;  2PAD A;  1ME3 A;  1MEG A;  3K8U A;  1CV8 A;  1POP A;  5CVN B;  2G6D A;  3BC3 A;  4WA6 A;  2XU5 A;  1PIP A;  3ERV A;  2VHS A;  1DF0 A;  1YAL A;  5A24 A;  1FH0 A;  4YYU A;  2AYO A;  3KWZ A;  2IBI A;  1AU0 A;  4YYV A;  1NB5 A;  3MTN A;  2Y5B A;  1MHW A;  3ZUA A;  2PBH A;  2CIO A;  4MZS A;  1K3B B;  4G54 A;  1PPP A;  4PP1 A;  2PRE A;  3U8E A;  2YJ9 A;  4MSX A;  4W5C A;  4YYQ A;  3P5W A;  3OF9 A;  2FYE A;  1F29 A;  2ARY A;  4I05 A;  2P0R A;  3USV A;  4QH6 A;  3WXE A;  1ITO A;  3OF8 A;  1F2A A;  4QRV A;  2AS8 A;  1KFU L;  3LFY A;  1YVB A;  2GHU A;  4YYW A;  1QDQ A;  4FJC A;  4YV8 A;  2XU4 A;  2HD5 A;  2F1G A;  2VHF A;  1KFX L;  1MS6 A;  3C9E A;  2AVW A;  3KX1 A;  1MEM A;  2R9C A;  4XR7 A;  4BS6 A;  4X6I A;  4QRX A;  3I06 A;  1CPJ A;  2BDZ A;  5EF4 A;  3RVV A;  3K24 A;  3H8C A;  1PCI A;  2NQA A;  1CTE A;  3GCB A;  1SNK A;  3IMA A;  3RVW A;  5PAD A;  3QJ3 A;  4Q8G A;  3BCN A;  3RVX A;  4W5B A;  2FTD A;  1GLO A;  1CS8 A;  2E01 A;  3QT4 A;  3OVX A;  2FO5 A;  3S3R A;  2DCD A;  1NL6 A;  2ACT A;  4QBB A;  5CVO B;  1GEC E;  2FRQ A;  1YK8 A;  3IHP A;  1AEC A;  1KXR A;  1STF E;  2YJ8 A;  1CVZ A;  4N8W A;  2DZY A;  3O0U A;  2PNS A;  2DC7 A;  3BPM A;  3MOR A;  1ME4 A;  3PNR A;  1DEU A;  2FT2 A;  2AUX A;  1QMY A;  3H6S A;  4YYR A;  3P5V A;  3I3T A;  2B1M A;  3NHE A;  2DC9 A;  4BS5 A;  4CDD B;  1MIR A;  2NQG A;  5CVM A;  1BQI A;  2YJB A;  3H89 A;  3MHH A;  3M99 A;  3LXS A;  1U9Q X;  3HHA A;  2XU3 A;  1QOL A;  3N3G A;  3HHI A;  3HD3 A;  1ATK A;  1PPN A;  1EWM A;  2AIM A;  3D6S A;  2JQG R;  2FQ9 A;  2H7J A;  3CH2 X;  1HUC B;  3CBK A;  5CHV A;  2G8E A;  2OUL A;  3S3Q A;  1AYV A;  1BP4 A;  1U9X A;  5EGW A;  2DC6 A;  3IUT A;  4PP2 E;  4CDF B;  3IEJ A;  3KKU A;  4N4Z A;  4OEL A;  1PPD A;  5CHT A;  1GMY A;  2YJC A;  3DF0 A;  4YYS A;  3P5U A;  2R9O A;  1QXP A;  3CBJ A;  2BDL A;  3N4C A;  2AUZ A;  1KHQ A;  1Q6K A;  8PCH A;  3O1G A;  3CH3 X;  1XKG A;  4PAD A;  4KLB A;  3TNX A;  1AYU A;  2ATO A;  2O6X A;  2CB5 A;  1YT7 A;  4BSQ A;  1PE6 A;  3H7D A;  2NQI A;  2R9F A;  1F2B A;  4CDE B;  1CQD A;  3HWN A;  4RY2 A;  3E1Z B;  2YJ2 A;  1VJV A;  4BQV A;  9PAP A;  4K7C A;  1ICF A;  1NQC A;  4I07 A;  3QSD A;  1CSB B;  2P7U A;  1NPZ A;  4CZW A;  1AIM A;  2R9N A;  6PAD A;  2DJF B;  1O0E A;  3OVZ A;  3BOW A;  1CJL A;  1TU6 A;  3PBH A;  4AXM A;  5F02 A;  2DCB A;  1EF7 A;  1YK7 A;  1EWP A;  4DMY A;  1ZCM A;  2AU1 A;  5FPW A;  2DCA A;  3KWB X;  3OIS A;  1EWO A;  5K16 A;  1PXV A;  1U9V A;  2NQD B;  4FIP A;  3MHS A;  4AXL A;  4I04 A;  3BPF A;  4CDC B;  4DMX A;  1GCB A;  1IWD A;  4QRG A;  1KHP A;  2R6N A;  2JQF R;  2Y6E A;  7PCK A;  1AYW A;  1EWL A;  2OP3 A;  1F2C A;  2G7Y A;  4FK5 A;  3P5X A;  3F75 A;  2AYN A;  2E02 A;  3IOQ A;  5JH3 A;  3KSE A;  1U5I A;  2E03 A;  4N79 A; 
#chains in the Genus database with same CATH topology
 3V6C A;  2DJG B;  3PRP A;  3PHX A;  4A5U A;  1TLO A;  1PPO A;  4P16 A;  4BOP A;  4PI3 A;  1Y08 A;  1AU4 A;  2FUD A;  3IV2 A;  2HWK A;  3MP2 A;  4Q8H A;  3PSE A;  2F7D A;  3WXF A;  4RKX A;  4HXD B;  4MZO A;  1ZIV A;  3PW3 A;  2DZZ A;  2FRA A;  3N3K A;  2B1N A;  2XU1 A;  1THE A;  2HXZ A;  1BY8 A;  2DC8 A;  3H8B A;  4OEM A;  4YVA A;  3AI8 A;  3IFU A;  4ZUX U;  4P6G A;  2G8J A;  1CB5 A;  1TL9 A;  1NLJ A;  4BPV A;  3KW9 A;  4P6E A;  1JQP A;  2HHN A;  4W4U A;  1S4V A;  2OZ2 A;  3V6E A;  1PBH A;  1SP4 B;  1Y4H A;  1PAD A;  3OQC A;  3MTV A;  1U9W A;  2J7Q A;  3B79 A;  3W31 A;  1NB3 A;  3PHW A;  1A6R A;  4X6H A;  4RF0 A;  4X6J A;  3WXG A;  2JTC A;  1AU2 A;  2UZJ A;  1BGO A;  3BB7 A;  1MDW A;  2R9M A;  3PDF A;  2JRI A;  3BWK A;  4RF1 A;  3W30 A;  1M6D A;  2C0Y A;  3KFQ A;  5JA7 A;  2HH5 A;  2P86 A;  4XUI A;  2GFO A;  3F5V A;  2DCC A;  4HWY A;  2IPP B;  1AU3 A;  3K9M A;  2E00 A;  1X9Y A;  2WBF X;  5J94 A;  1VSN A;  3ZNH A;  2PAD A;  1ME3 A;  1MEG A;  3K8U A;  1CV8 A;  4BOS A;  2J7Q C;  1POP A;  5CVN B;  2G6D A;  3BC3 A;  4WA6 A;  2XU5 A;  1PIP A;  3ERV A;  2VHS A;  5JZE A;  1DF0 A;  1YAL A;  4D8I A;  4IP3 A;  5A24 A;  1FH0 A;  4YYU A;  2AYO A;  3KWZ A;  2IBI A;  1AU0 A;  4YYV A;  1NB5 A;  5KO3 A;  3MTN A;  2Y5B A;  1MHW A;  3ZUA A;  2PBH A;  3BBA A;  2CIO A;  4MZS A;  1K3B B;  4G54 A;  1PPP A;  4PP1 A;  2PRE A;  3U8E A;  2YJ9 A;  4MSX A;  4W5C A;  4YYQ A;  3P5W A;  3OF9 A;  3TMP A;  2FYE A;  1F29 A;  2ARY A;  4I05 A;  2P0R A;  3USV A;  4QH6 A;  3WXE A;  1ITO A;  3OF8 A;  1F2A A;  4QRV A;  2AS8 A;  1KFU L;  3LFY A;  1YVB A;  4D8E A;  2GHU A;  4IUM A;  4BOU A;  1QDQ A;  4YYW A;  4FJC A;  4YV8 A;  4OW0 A;  2XU4 A;  2HD5 A;  2F1G A;  2VHF A;  1KFX L;  1MS6 A;  3C9E A;  2AVW A;  3KX1 A;  1MEM A;  4OVZ B;  4ZTB A;  2R9C A;  4XR7 A;  2DOS A;  4BS6 A;  4X6I A;  4QRX A;  3I06 A;  2BTW A;  1CPJ A;  2BDZ A;  5EF4 A;  3RVV A;  3K24 A;  3H8C A;  1PCI A;  1DKI A;  3TRK A;  2NQA A;  1CTE A;  3GCB A;  1SNK A;  3IMA A;  3RVW A;  5PAD A;  3QJ3 A;  3PHU A;  3BCN A;  4Q8G A;  3RVX A;  4W5B A;  2FE8 A;  2FTD A;  1GLO A;  1CS8 A;  2E01 A;  3QT4 A;  3C0R A;  3OVX A;  2FO5 A;  3S3R A;  2DCD A;  1NL6 A;  2ACT A;  4MM3 B;  4QBB A;  5CVO B;  1GEC E;  2FRQ A;  1YK8 A;  3IHP A;  1AEC A;  1KXR A;  1STF E;  2YJ8 A;  1CVZ A;  4N8W A;  2DZY A;  3O0U A;  2PNS A;  2DC7 A;  3BPM A;  3MOR A;  1ME4 A;  3PNR A;  1DEU A;  2FT2 A;  2AUX A;  1QMY A;  3E9S A;  3H6S A;  4YYR A;  3P5V A;  3I3T A;  2B1M A;  4R3D A;  3NHE A;  2DC9 A;  4BS5 A;  4CDD B;  1MIR A;  2NQG A;  5EZS A;  5CVM A;  1BQI A;  2YJB A;  3H89 A;  3MHH A;  3M99 A;  3LXS A;  1U9Q X;  3HHA A;  2XU3 A;  1QOL A;  3N3G A;  3HHI A;  3HD3 A;  1ATK A;  1PPN A;  1EWM A;  2AIM A;  3D6S A;  5EZQ A;  2JQG R;  2FQ9 A;  2H7J A;  3CH2 X;  1HUC B;  3MJ5 A;  3CBK A;  5CHV A;  2G8E A;  2OUL A;  3S3Q A;  1AYV A;  1BP4 A;  1U9X A;  4XZX A;  5EGW A;  2DC6 A;  3IUT A;  4PP2 E;  4CDF B;  3IEJ A;  3KKU A;  5E6J A;  4N4Z A;  4WUR A;  4PT5 A;  4OEL A;  1PPD A;  5CHT A;  1GMY A;  2YJC A;  3DF0 A;  4YYS A;  3P5U A;  2R9O A;  1QXP A;  3CBJ A;  2BDL A;  3B21 A;  4D8B A;  3N4C A;  2BTW B;  2AUZ A;  1KHQ A;  1Q6K A;  8PCH A;  3O1G A;  3CH3 X;  3O65 A;  1XKG A;  4PAD A;  4KLB A;  3TNX A;  1AYU A;  2ATO A;  2O6X A;  2BU3 A;  1YZB A;  2CB5 A;  1YT7 A;  4BSQ A;  1PE6 A;  3H7D A;  2NQI A;  2R9F A;  1F2B A;  4CDE B;  1CQD A;  3HWN A;  4RY2 A;  3E1Z B;  2YJ2 A;  4OVZ A;  1VJV A;  4BQV A;  9PAP A;  4K7C A;  1ICF A;  1NQC A;  4I07 A;  3QSD A;  4RNA A;  1CSB B;  1UKF A;  2P7U A;  1NPZ A;  4CZW A;  1AIM A;  3PRM A;  2R9N A;  6PAD A;  2DJF B;  1O0E A;  3OVZ A;  3BY4 A;  3BOW A;  1CJL A;  1TU6 A;  3PBH A;  4AXM A;  5F02 A;  2DCB A;  1EF7 A;  1PVJ A;  1YK7 A;  4GUA A;  4BOQ A;  1EWP A;  3RNV A;  4DMY A;  4BOZ A;  4MI7 A;  1ZCM A;  2AU1 A;  5FPW A;  2DCA A;  3KWB X;  3OIS A;  1EWO A;  5K16 A;  1PXV A;  1U9V A;  2NQD B;  4FIP A;  3MHS A;  2Z84 A;  4AXL A;  4I04 A;  3BPF A;  4CDC B;  4M0W A;  4REZ A;  4DMX A;  3PT2 A;  1GCB A;  1IWD A;  4QRG A;  1KHP A;  2R6N A;  2JQF R;  2Y6E A;  7PCK A;  1AYW A;  1EWL A;  2OP3 A;  1F2C A;  2AGA A;  2G7Y A;  4FK5 A;  3P5X A;  3F75 A;  2AYN A;  2E02 A;  3IOQ A;  5JH3 A;  3KSE A;  1U5I A;  2E03 A;  4N79 A; 
#chains in the Genus database with same CATH homology
 3V6C A;  2DJG B;  1TLO A;  1PPO A;  4PI3 A;  1Y08 A;  1AU4 A;  2FUD A;  3IV2 A;  4Q8H A;  2F7D A;  3WXF A;  4MZO A;  1ZIV A;  3PW3 A;  2DZZ A;  2FRA A;  3N3K A;  2B1N A;  2XU1 A;  1THE A;  2HXZ A;  1BY8 A;  2DC8 A;  3H8B A;  4OEM A;  4YVA A;  1W6F A;  3AI8 A;  4ZUX U;  4P6G A;  2G8J A;  1CB5 A;  1TL9 A;  1NLJ A;  4BPV A;  3KW9 A;  4P6E A;  1JQP A;  2HHN A;  4W4U A;  1S4V A;  2OZ2 A;  3V6E A;  1PBH A;  1SP4 B;  1Y4H A;  1PAD A;  1U9W A;  3B79 A;  1NB3 A;  1A6R A;  4X6H A;  4X6J A;  3WXG A;  1AU2 A;  1BGO A;  1MDW A;  2R9M A;  3PDF A;  3BWK A;  1M6D A;  2C0Y A;  3KFQ A;  5JA7 A;  2HH5 A;  2P86 A;  4XUI A;  4NV8 A;  2GFO A;  3F5V A;  2DCC A;  4HWY A;  2IPP B;  1AU3 A;  3K9M A;  2E00 A;  1X9Y A;  2WBF X;  5J94 A;  1VSN A;  2PAD A;  1ME3 A;  1MEG A;  3K8U A;  1CV8 A;  1POP A;  5CVN B;  2G6D A;  3BC3 A;  4WA6 A;  2XU5 A;  1PIP A;  3ERV A;  2VHS A;  1DF0 A;  1YAL A;  5A24 A;  1FH0 A;  4YYU A;  2VFC A;  2AYO A;  3KWZ A;  2IBI A;  1AU0 A;  4YYV A;  1NB5 A;  3MTN A;  2Y5B A;  1MHW A;  3ZUA A;  2PBH A;  2CIO A;  4MZS A;  1K3B B;  4G54 A;  1PPP A;  4PP1 A;  2PRE A;  3U8E A;  2YJ9 A;  4MSX A;  4W5C A;  4YYQ A;  3P5W A;  3D9W A;  3OF9 A;  2FYE A;  1F29 A;  2ARY A;  4I05 A;  2P0R A;  3USV A;  4GUZ A;  4QH6 A;  3WXE A;  1ITO A;  3OF8 A;  1F2A A;  4QRV A;  2AS8 A;  1KFU L;  3LFY A;  1YVB A;  2GHU A;  4YYW A;  1QDQ A;  4FJC A;  4YV8 A;  2XU4 A;  2HD5 A;  2F1G A;  2VHF A;  1KFX L;  1MS6 A;  3C9E A;  2AVW A;  3KX1 A;  1MEM A;  2R9C A;  4XR7 A;  4BS6 A;  4X6I A;  4QRX A;  3I06 A;  1CPJ A;  2BDZ A;  5EF4 A;  3RVV A;  3K24 A;  3H8C A;  1PCI A;  2NQA A;  1CTE A;  3GCB A;  1SNK A;  3IMA A;  3RVW A;  5PAD A;  3QJ3 A;  4Q8G A;  3BCN A;  3RVX A;  1GX3 A;  4W5B A;  2FTD A;  1GLO A;  1CS8 A;  2E01 A;  3QT4 A;  2VFB A;  3OVX A;  2FO5 A;  3S3R A;  2DCD A;  1NL6 A;  2ACT A;  4QBB A;  5CVO B;  1GEC E;  2FRQ A;  1YK8 A;  3IHP A;  1AEC A;  1KXR A;  1STF E;  2YJ8 A;  1CVZ A;  4N8W A;  2DZY A;  3LTW A;  3O0U A;  2PNS A;  2DC7 A;  3BPM A;  3MOR A;  1ME4 A;  3PNR A;  1DEU A;  2FT2 A;  2AUX A;  1QMY A;  3H6S A;  4YYR A;  3P5V A;  3I3T A;  2B1M A;  3NHE A;  2DC9 A;  4BS5 A;  4CDD B;  1MIR A;  2NQG A;  5CVM A;  1BQI A;  2YJB A;  3H89 A;  3MHH A;  3M99 A;  1W4T A;  3LXS A;  1U9Q X;  4NV7 A;  3HHA A;  2XU3 A;  1QOL A;  3N3G A;  4BGF A;  3HHI A;  4B55 A;  3HD3 A;  1ATK A;  1PPN A;  1EWM A;  2AIM A;  3D6S A;  2JQG R;  2FQ9 A;  2H7J A;  3CH2 X;  1HUC B;  3CBK A;  1W5R A;  5CHV A;  2G8E A;  2OUL A;  3S3Q A;  1AYV A;  1BP4 A;  1U9X A;  5EGW A;  2DC6 A;  3IUT A;  4PP2 E;  4CDF B;  3IEJ A;  3KKU A;  4N4Z A;  4OEL A;  1PPD A;  2BSZ A;  5CHT A;  1GMY A;  2YJC A;  3DF0 A;  4YYS A;  3P5U A;  2R9O A;  1QXP A;  3CBJ A;  2BDL A;  3N4C A;  2AUZ A;  1KHQ A;  1Q6K A;  8PCH A;  3O1G A;  3CH3 X;  1XKG A;  4PAD A;  4KLB A;  3TNX A;  1AYU A;  2ATO A;  2O6X A;  2CB5 A;  1YT7 A;  4BSQ A;  1PE6 A;  3H7D A;  2NQI A;  2R9F A;  1F2B A;  4CDE B;  1CQD A;  3HWN A;  4RY2 A;  3E1Z B;  2YJ2 A;  1VJV A;  4BQV A;  9PAP A;  4K7C A;  1ICF A;  1NQC A;  4I07 A;  3QSD A;  1CSB B;  2P7U A;  1NPZ A;  4CZW A;  1AIM A;  2R9N A;  6PAD A;  2DJF B;  1O0E A;  3OVZ A;  3BOW A;  1CJL A;  1TU6 A;  3PBH A;  4AXM A;  5F02 A;  2DCB A;  1EF7 A;  1YK7 A;  1EWP A;  4DMY A;  1ZCM A;  2AU1 A;  5FPW A;  2DCA A;  3KWB X;  3OIS A;  1EWO A;  5K16 A;  1PXV A;  1U9V A;  2NQD B;  4FIP A;  3MHS A;  4AXL A;  4I04 A;  3BPF A;  4CDC B;  4DMX A;  1GCB A;  1IWD A;  4QRG A;  1KHP A;  2R6N A;  2JQF R;  2Y6E A;  7PCK A;  1AYW A;  1EWL A;  2OP3 A;  1E2T A;  1F2C A;  2G7Y A;  4FK5 A;  3P5X A;  3F75 A;  2AYN A;  2E02 A;  3IOQ A;  5JH3 A;  3KSE A;  4C5P A;  1U5I A;  2E03 A;  4N79 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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