4I05A

Structure of intermediate processing form of cathepsin b1 from schistosoma mansoni
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
277
structure length
276
Chain Sequence
GARREEPDLRRTRRPTVDHNDWNVEIPSSFDSRKKWPRCKSIATIRDQSRCGSWAFGAVEAMSDRSCIQSGGKQNVELSAVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGRDECSIESEVTAGRIN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch
pubmed doi rcsb
molecule tags Hydrolase
source organism Schistosoma mansoni
molecule keywords Cathepsin B-like peptidase (C01 family)
total genus 95
structure length 276
sequence length 277
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 2012-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4i05A00
1NLJA 4YYUA 1SNKA 2WBFX 1EWPA 1TLOA 1YK7A 2NQIA 3OF9A 1U9WA 1POPA 4OELA 1MDWA 2R9CA 1AU0A 4PADA 1CJLA 1K3BB 2PNSA 3RVXA 2FRAA 3P5UA 2PBHA 4PP1A 4I05A 2Y5BA 1CS8A 1IWDA 1PADA 3OISA 2AIMA 2XU5A 2XU4A 3H7DA 5CVMA 2HD5A 2AUZA 4RY2A 4W5CA 1F2CA 2GFOA 3PBHA 1QDQA 5JH3A 2ARYA 2DJFB 3AI8A 4Q8HA 1TU6A 3TNXA 1GCBA 3O0UA 2E02A 3F75A 4X6HA 1THEA 3B79A 4W5BA 3F5VA 5EGWA 1AU2A 1NB5A 4DMYA 3BC3A 3BCNA 1CVZA 5A24A 2B1MA 2DC9A 4MSXA 6PADA 4P6EA 3N3GA 2E01A 3KWZA 4Q8GA 1KHQA 1ICFA 1ITOA 1PXVA 1A6RA 2FYEA 1AYVA 2DCCA 5JA7A 4CDDB 4CDFB 5PADA 4PI3A 1YVBA 3BPFA 4FK5A 3WXGA 1CB5A 2GHUA 1QXPA 4PP2E 1Y4HA 4BPVA 2NQGA 4YYVA 2AU1A 2AYNA 2DCDA 1Y08A 1AU3A 4WA6A 2DCAA 1EWOA 1VJVA 1BY8A 4I07A 1TL9A 2VHFA 3IEJA 1U9XA 3H8CA 3LXSA 4QBBA 3ZUAA 1NQCA 1O0EA 2FUDA 2AVWA 1PIPA 1JQPA 2CB5A 2HH5A 3H8BA 3CBJA 1VSNA 3PW3A 5F02A 2P86A 3HHIA 3MHSA 4HWYA 2BDZA 4QRVA 1DF0A 2PREA 3QJ3A 1ME3A 3O1GA 2E03A 1EF7A 2DJGB 4I04A 3S3QA 1PE6A 2H7JA 2P7UA 2NQAA 2JQGR 2FT2A 3RVWA 4G54A 4CZWA 1Q6KA 3N4CA 1AU4A 2FO5A 1CV8A 2XU1A 3MORA 3DF0A 3MTNA 4AXMA 3PNRA 1F2AA 1BGOA 2YJ8A 3MHHA 2IPPB 2ATOA 3IOQA 3HHAA 2PADA 4BS5A 2DZYA 1EWMA 4YV8A 1KHPA 2FQ9A 2G7YA 3HWNA 2B1NA 1U9QX 1STFE 2AUXA 3S3RA 1NB3A 5J94A 4KLBA 3USVA 3I3TA 2FTDA 2FRQA 1X9YA 4K7CA 3KWBX 2DZZA 5CHVA 3KKUA 4X6JA 2DC8A 1HUCB 4CDEB 1ZIVA 2R9FA 3V6CA 4FJCA 5K16A 4AXLA 1F2BA 3H89A 4FIPA 9PAPA 4DMXA 2F7DA 1KFUL 2JQFR 3E1ZB 1FH0A 1QMYA 4XR7A 3N3KA 4N79A 2YJCA 1MEGA 2OZ2A 1BP4A 3WXEA 1S4VA 4P6GA 1PCIA 1AYWA 1YK8A 3H6SA 3IMAA 3P5VA 2OP3A 2DCBA 1U5IA 1NL6A 1BQIA 3K24A 3C9EA 3IHPA 1AYUA 2P0RA 1KFXL 2R6NA 2YJ2A 2YJ9A 3ERVA 1SP4B 2R9MA 3QT4A 2G8JA 4YYRA 4QRXA 2DC7A 3IV2A 5CVOB 1F29A 3OF8A 4YYQA 3CBKA 1M6DA 3M99A 7PCKA 5CVNB 2AYOA 2DC6A 2AS8A 2O6XA 2R9OA 3CH2X 1PPDA 4XUIA 3KFQA 3GCBA 1CTEA 3QSDA 1ME4A 3KSEA 3P5XA 2VHSA 3K8UA 4BQVA 2G8EA 1MHWA 4ZUXU 1MS6A 4QH6A 3NHEA 3OVZA 1CPJA 2R9NA 1GECE 4OEMA 2G6DA 3RVVA 1NPZA 1CQDA 1GLOA 2BDLA 2HXZA 3OVXA 3U8EA 2F1GA 4BS6A 4QRGA 4X6IA 3LFYA 3BWKA 3I06A 1QOLA 1CSBB 4N4ZA 1ZCMA 8PCHA 4YYWA 2XU3A 5CHTA 1MIRA 1PBHA 1KXRA 1PPNA 1ATKA 3P5WA 2IBIA 3IUTA 3BOWA 2OULA 3CH3X 3PDFA 2Y6EA 1PPPA 3WXFA 4BSQA 2YJBA 4MZSA 4YVAA 1YT7A 1GMYA 4YYSA 1EWLA 3K9MA 1DEUA 2ACTA 3HD3A 4N8WA 1U9VA 2CIOA 2NQDB 4MZOA 5EF4A 5FPWA 1AECA 3BPMA 1AIMA 3D6SA 3KW9A 2E00A 3KX1A 1PPOA 1MEMA 2HHNA 2C0YA 1YALA 4W4UA 1XKGA 4CDCB 3V6EA
chains in the Genus database with same CATH superfamily
1NLJA 4YYUA 1SNKA 2WBFX 1EWPA 1TLOA 1YK7A 2NQIA 3MP2A 4D8BA 3OF9A 1U9WA 1POPA 4OELA 1MDWA 2R9CA 1AU0A 4PADA 4RNAA 1CJLA 1K3BB 2PNSA 3RVXA 2FRAA 3P5UA 2PBHA 4PP1A 3TMPA 4I05A 2Y5BA 1CS8A 3C0RA 1IWDA 1PADA 3OISA 2AIMA 4M0WA 2XU5A 2XU4A 3H7DA 5CVMA 2HD5A 2AUZA 4RY2A 4W5CA 3OQCA 1F2CA 2GFOA 3PBHA 3V6EA 1QDQA 5JH3A 3BB7A 2ARYA 2DJFB 3AI8A 4Q8HA 3TRKA 1TU6A 3TNXA 1GCBA 4D8IA 3O0UA 2E02A 3F75A 4X6HA 1THEA 3B79A 4W5BA 3F5VA 5EGWA 1AU2A 1NB5A 4DMYA 3BC3A 3BCNA 1CVZA 3PHXA 5A24A 2B1MA 2DC9A 4MSXA 3PSEA 1UKFA 6PADA 4P6EA 3N3GA 2E01A 3KWZA 3ZNHA 4Q8GA 1KHQA 1ICFA 1ITOA 1PXVA 1A6RA 2FYEA 4PT5A 1AYVA 2AGAA 2DCCA 5JA7A 2BTWB 4CDDB 4CDFB 5PADA 4PI3A 1YVBA 3BPFA 4FK5A 3WXGA 1CB5A 2GHUA 1QXPA 3MTVA 5E6JA 4PP2E 1Y4HA 4BPVA 4XZXA 2NQGA 4YYVA 2AU1A 2AYNA 2BU3A 2DCDA 4P16A 1Y08A 1AU3A 4WA6A 2DCAA 1EWOA 1VJVA 1BY8A 4I07A 1TL9A 2VHFA 3IEJA 1U9XA 3H8CA 3LXSA 4QBBA 3ZUAA 1NQCA 3W31A 1O0EA 2FUDA 2AVWA 1PIPA 1JQPA 2CB5A 2HH5A 3H8BA 3CBJA 1VSNA 3PW3A 5F02A 2P86A 3HHIA 3MHSA 4HWYA 2BDZA 4QRVA 4OVZB 1DF0A 2PREA 3BBAA 3QJ3A 2FE8A 1ME3A 3O1GA 2E03A 1EF7A 2DJGB 4I04A 3S3QA 4RF1A 1PE6A 2H7JA 2P7UA 2NQAA 2JQGR 1DKIA 2FT2A 3RVWA 4G54A 4CZWA 1Q6KA 3N4CA 1AU4A 2FO5A 1CV8A 2XU1A 3MORA 3DF0A 4D8EA 3MTNA 4AXMA 3PNRA 1F2AA 1BGOA 2YJ8A 3MHHA 2IPPB 4MM3B 2ATOA 3IOQA 3HHAA 2PADA 4BS5A 2DZYA 1EWMA 4YV8A 1KHPA 2FQ9A 4RKXA 3E9SA 2G7YA 3HWNA 2B1NA 1U9QX 1STFE 2UZJA 2AUXA 3S3RA 1NB3A 5J94A 4KLBA 3USVA 3I3TA 4REZA 2FTDA 2FRQA 1X9YA 4IP3A 4K7CA 3KWBX 2DZZA 5CHVA 2JTCA 3KKUA 4X6JA 2DC8A 3B21A 1HUCB 4CDEB 1ZIVA 2R9FA 3V6CA 4FJCA 4BOSA 5K16A 4AXLA 5EZSA 1F2BA 3H89A 4BOPA 4FIPA 4ZTBA 9PAPA 4DMXA 2F7DA 4HXDB 1KFUL 2JQFR 3E1ZB 1FH0A 1QMYA 4XR7A 3N3KA 4N79A 2YJCA 1MEGA 2OZ2A 3PRPA 4BOQA 4OW0A 1BP4A 3WXEA 1S4VA 4P6GA 4IUMA 1PCIA 1AYWA 2Z84A 1YK8A 4A5UA 3H6SA 3IMAA 3RNVA 3P5VA 2OP3A 2DCBA 4GUAA 5EZQA 1U5IA 1NL6A 3O65A 1BQIA 3PT2A 3K24A 3C9EA 3IHPA 1AYUA 2P0RA 1KFXL 2R6NA 2YJ2A 2YJ9A 3ERVA 1SP4B 2R9MA 3QT4A 2G8JA 4YYRA 4QRXA 2DC7A 3IV2A 5CVOB 5JZEA 1F29A 3OF8A 3IFUA 4MI7A 4YYQA 3CBKA 1M6DA 3M99A 7PCKA 5CVNB 3BY4A 2AYOA 2DC6A 2AS8A 2O6XA 2R9OA 3CH2X 1PPDA 4XUIA 2HWKA 3MJ5A 3KFQA 3GCBA 1CTEA 3QSDA 1ME4A 3KSEA 3P5XA 2VHSA 4BOZA 3K8UA 4BQVA 2G8EA 1MHWA 4ZUXU 1MS6A 4QH6A 3NHEA 3OVZA 4WURA 1CPJA 2R9NA 1GECE 4OEMA 2G6DA 3RVVA 1NPZA 1CQDA 1GLOA 2BDLA 2HXZA 3OVXA 3U8EA 2F1GA 4BS6A 2JRIA 4QRGA 4X6IA 2J7QA 3LFYA 3BWKA 2BTWA 3I06A 1QOLA 1CSBB 4N4ZA 1ZCMA 8PCHA 4YYWA 2XU3A 5CHTA 1MIRA 1PBHA 1KXRA 1PPNA 1ATKA 3P5WA 2IBIA 3IUTA 3BOWA 2J7QC 1PVJA 2OULA 3CH3X 3PDFA 3PHWA 2Y6EA 1PPPA 3WXFA 4BSQA 2YJBA 4MZSA 4YVAA 1YT7A 1GMYA 4YYSA 3PRMA 1EWLA 4RF0A 3K9MA 1DEUA 2ACTA 4BOUA 3HD3A 4N8WA 1U9VA 2CIOA 2NQDB 4MZOA 5EF4A 5FPWA 1AECA 3BPMA 1AIMA 3D6SA 3KW9A 5KO3A 2E00A 3KX1A 1PPOA 4OVZA 3PHUA 1MEMA 2HHNA 4R3DA 2C0YA 2DOSA 3W30A 1YALA 4W4UA 1XKGA 4CDCB 1YZBA
chains in the Genus database with same CATH topology
1NLJA 4YYUA 1SNKA 2WBFX 1EWPA 1TLOA 1YK7A 2NQIA 3OF9A 1U9WA 1POPA 4OELA 1MDWA 2R9CA 1AU0A 4PADA 1CJLA 1K3BB 2PNSA 3D9WA 2FRAA 3RVXA 2VFCA 3P5UA 2PBHA 4PP1A 4I05A 2Y5BA 1CS8A 1W4TA 1IWDA 1PADA 3OISA 2AIMA 2XU5A 2XU4A 3H7DA 5CVMA 2HD5A 2AUZA 4RY2A 4W5CA 1F2CA 2GFOA 3PBHA 1QDQA 5JH3A 2ARYA 2DJFB 3AI8A 4Q8HA 1TU6A 3TNXA 1GCBA 3O0UA 2E02A 3F75A 4X6HA 1THEA 3B79A 4W5BA 3F5VA 5EGWA 1AU2A 1NB5A 4DMYA 3BC3A 3BCNA 1CVZA 5A24A 2B1MA 2DC9A 4MSXA 4B55A 6PADA 4P6EA 3N3GA 2E01A 3KWZA 4Q8GA 1KHQA 1ICFA 1ITOA 1PXVA 1A6RA 2BSZA 2FYEA 1AYVA 2DCCA 5JA7A 4GUZA 4CDDB 4CDFB 5PADA 4PI3A 1YVBA 3BPFA 4FK5A 3WXGA 1CB5A 2GHUA 1QXPA 4PP2E 1Y4HA 4BPVA 2NQGA 4YYVA 2AU1A 2AYNA 2DCDA 1Y08A 1AU3A 4WA6A 2DCAA 1EWOA 1VJVA 1BY8A 4I07A 1TL9A 2VHFA 3IEJA 1U9XA 3H8CA 3LXSA 4QBBA 3ZUAA 1NQCA 1O0EA 2FUDA 2AVWA 1PIPA 1JQPA 2CB5A 2HH5A 3H8BA 3CBJA 1VSNA 3PW3A 5F02A 2P86A 3HHIA 3MHSA 4HWYA 2BDZA 4QRVA 1DF0A 2PREA 3QJ3A 1ME3A 3O1GA 2E03A 1EF7A 2DJGB 4I04A 3S3QA 1PE6A 2H7JA 2P7UA 2NQAA 2JQGR 2FT2A 3RVWA 4G54A 4CZWA 1Q6KA 3N4CA 1AU4A 2FO5A 1CV8A 2XU1A 3MORA 3DF0A 3MTNA 4AXMA 3PNRA 1F2AA 1BGOA 2YJ8A 1GX3A 3MHHA 2IPPB 2ATOA 3IOQA 3HHAA 2PADA 4BS5A 2DZYA 1EWMA 1W6FA 4YV8A 1KHPA 2FQ9A 2G7YA 3HWNA 2B1NA 1U9QX 1STFE 2AUXA 3S3RA 1NB3A 5J94A 4KLBA 3USVA 3I3TA 2FTDA 2FRQA 1X9YA 4K7CA 3KWBX 2DZZA 5CHVA 3KKUA 4X6JA 2DC8A 1HUCB 4CDEB 1ZIVA 2R9FA 3V6CA 4FJCA 5K16A 4AXLA 1F2BA 3H89A 4FIPA 9PAPA 4DMXA 2F7DA 1KFUL 2JQFR 3E1ZB 1FH0A 1QMYA 4XR7A 3N3KA 4N79A 2YJCA 1MEGA 2OZ2A 1BP4A 3WXEA 4BGFA 1S4VA 4P6GA 1PCIA 1AYWA 1YK8A 3H6SA 3IMAA 4NV8A 3P5VA 2OP3A 2DCBA 1U5IA 1NL6A 1BQIA 3LTWA 3K24A 3C9EA 3IHPA 1AYUA 2P0RA 1KFXL 2R6NA 2YJ2A 2YJ9A 3ERVA 1SP4B 2R9MA 3QT4A 2G8JA 4YYRA 4QRXA 2DC7A 3IV2A 5CVOB 1F29A 3OF8A 4YYQA 3CBKA 1M6DA 3M99A 7PCKA 5CVNB 2AYOA 2DC6A 2AS8A 2O6XA 2R9OA 3CH2X 1PPDA 4XUIA 3KFQA 3GCBA 1CTEA 3QSDA 1ME4A 1E2TA 3KSEA 3P5XA 2VHSA 3K8UA 4BQVA 2G8EA 1MHWA 4ZUXU 1MS6A 4QH6A 3NHEA 3OVZA 4C5PA 1CPJA 2R9NA 1GECE 4OEMA 2G6DA 3RVVA 1NPZA 1CQDA 1GLOA 2BDLA 2HXZA 3OVXA 3U8EA 2F1GA 4BS6A 4QRGA 4X6IA 3LFYA 3BWKA 3I06A 1QOLA 1CSBB 4N4ZA 1ZCMA 8PCHA 4YYWA 2XU3A 5CHTA 1MIRA 1PBHA 1KXRA 1PPNA 1ATKA 3P5WA 2IBIA 3IUTA 3BOWA 2OULA 3CH3X 3PDFA 2Y6EA 1PPPA 3WXFA 4BSQA 2YJBA 4MZSA 4YVAA 1YT7A 1GMYA 4YYSA 1EWLA 3K9MA 1DEUA 2ACTA 3HD3A 4N8WA 1U9VA 2CIOA 2NQDB 4MZOA 5EF4A 5FPWA 1AECA 3BPMA 1AIMA 4NV7A 3D6SA 3KW9A 2E00A 3KX1A 1PPOA 1W5RA 1MEMA 2HHNA 2C0YA 1YALA 2VFBA 4W4UA 1XKGA 4CDCB 3V6EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NLJ A;  4YYU A;  1SNK A;  2WBF X;  1EWP A;  1TLO A;  1YK7 A;  2NQI A;  3OF9 A;  1U9W A;  1POP A;  4OEL A;  1MDW A;  2R9C A;  1AU0 A;  4PAD A;  1CJL A;  1K3B B;  2PNS A;  3RVX A;  2FRA A;  3P5U A;  2PBH A;  4PP1 A;  4I05 A;  2Y5B A;  1CS8 A;  1IWD A;  1PAD A;  3OIS A;  2AIM A;  2XU5 A;  2XU4 A;  3H7D A;  5CVM A;  2HD5 A;  2AUZ A;  4RY2 A;  4W5C A;  1F2C A;  2GFO A;  3PBH A;  1QDQ A;  5JH3 A;  2ARY A;  2DJF B;  3AI8 A;  4Q8H A;  1TU6 A;  3TNX A;  1GCB A;  3O0U A;  2E02 A;  3F75 A;  4X6H A;  1THE A;  3B79 A;  4W5B A;  3F5V A;  5EGW A;  1AU2 A;  1NB5 A;  4DMY A;  3BC3 A;  3BCN A;  1CVZ A;  5A24 A;  2B1M A;  2DC9 A;  4MSX A;  6PAD A;  4P6E A;  3N3G A;  2E01 A;  3KWZ A;  4Q8G A;  1KHQ A;  1ICF A;  1ITO A;  1PXV A;  1A6R A;  2FYE A;  1AYV A;  2DCC A;  5JA7 A;  4CDD B;  4CDF B;  5PAD A;  4PI3 A;  1YVB A;  3BPF A;  4FK5 A;  3WXG A;  1CB5 A;  2GHU A;  1QXP A;  4PP2 E;  1Y4H A;  4BPV A;  2NQG A;  4YYV A;  2AU1 A;  2AYN A;  2DCD A;  1Y08 A;  1AU3 A;  4WA6 A;  2DCA A;  1EWO A;  1VJV A;  1BY8 A;  4I07 A;  1TL9 A;  2VHF A;  3IEJ A;  1U9X A;  3H8C A;  3LXS A;  4QBB A;  3ZUA A;  1NQC A;  1O0E A;  2FUD A;  2AVW A;  1PIP A;  1JQP A;  2CB5 A;  2HH5 A;  3H8B A;  3CBJ A;  1VSN A;  3PW3 A;  5F02 A;  2P86 A;  3HHI A;  3MHS A;  4HWY A;  2BDZ A;  4QRV A;  1DF0 A;  2PRE A;  3QJ3 A;  1ME3 A;  3O1G A;  2E03 A;  1EF7 A;  2DJG B;  4I04 A;  3S3Q A;  1PE6 A;  2H7J A;  2P7U A;  2NQA A;  2JQG R;  2FT2 A;  3RVW A;  4G54 A;  4CZW A;  1Q6K A;  3N4C A;  1AU4 A;  2FO5 A;  1CV8 A;  2XU1 A;  3MOR A;  3DF0 A;  3MTN A;  4AXM A;  3PNR A;  1F2A A;  1BGO A;  2YJ8 A;  3MHH A;  2IPP B;  2ATO A;  3IOQ A;  3HHA A;  2PAD A;  4BS5 A;  2DZY A;  1EWM A;  4YV8 A;  1KHP A;  2FQ9 A;  2G7Y A;  3HWN A;  2B1N A;  1U9Q X;  1STF E;  2AUX A;  3S3R A;  1NB3 A;  5J94 A;  4KLB A;  3USV A;  3I3T A;  2FTD A;  2FRQ A;  1X9Y A;  4K7C A;  3KWB X;  2DZZ A;  5CHV A;  3KKU A;  4X6J A;  2DC8 A;  1HUC B;  4CDE B;  1ZIV A;  2R9F A;  3V6C A;  4FJC A;  5K16 A;  4AXL A;  1F2B A;  3H89 A;  4FIP A;  9PAP A;  4DMX A;  2F7D A;  1KFU L;  2JQF R;  3E1Z B;  1FH0 A;  1QMY A;  4XR7 A;  3N3K A;  4N79 A;  2YJC A;  1MEG A;  2OZ2 A;  1BP4 A;  3WXE A;  1S4V A;  4P6G A;  1PCI A;  1AYW A;  1YK8 A;  3H6S A;  3IMA A;  3P5V A;  2OP3 A;  2DCB A;  1U5I A;  1NL6 A;  1BQI A;  3K24 A;  3C9E A;  3IHP A;  1AYU A;  2P0R A;  1KFX L;  2R6N A;  2YJ2 A;  2YJ9 A;  3ERV A;  1SP4 B;  2R9M A;  3QT4 A;  2G8J A;  4YYR A;  4QRX A;  2DC7 A;  3IV2 A;  5CVO B;  1F29 A;  3OF8 A;  4YYQ A;  3CBK A;  1M6D A;  3M99 A;  7PCK A;  5CVN B;  2AYO A;  2DC6 A;  2AS8 A;  2O6X A;  2R9O A;  3CH2 X;  1PPD A;  4XUI A;  3KFQ A;  3GCB A;  1CTE A;  3QSD A;  1ME4 A;  3KSE A;  3P5X A;  2VHS A;  3K8U A;  4BQV A;  2G8E A;  1MHW A;  4ZUX U;  1MS6 A;  4QH6 A;  3NHE A;  3OVZ A;  1CPJ A;  2R9N A;  1GEC E;  4OEM A;  2G6D A;  3RVV A;  1NPZ A;  1CQD A;  1GLO A;  2BDL A;  2HXZ A;  3OVX A;  3U8E A;  2F1G A;  4BS6 A;  4QRG A;  4X6I A;  3LFY A;  3BWK A;  3I06 A;  1QOL A;  1CSB B;  4N4Z A;  1ZCM A;  8PCH A;  4YYW A;  2XU3 A;  5CHT A;  1MIR A;  1PBH A;  1KXR A;  1PPN A;  1ATK A;  3P5W A;  2IBI A;  3IUT A;  3BOW A;  2OUL A;  3CH3 X;  3PDF A;  2Y6E A;  1PPP A;  3WXF A;  4BSQ A;  2YJB A;  4MZS A;  4YVA A;  1YT7 A;  1GMY A;  4YYS A;  1EWL A;  3K9M A;  1DEU A;  2ACT A;  3HD3 A;  4N8W A;  1U9V A;  2CIO A;  2NQD B;  4MZO A;  5EF4 A;  5FPW A;  1AEC A;  3BPM A;  1AIM A;  3D6S A;  3KW9 A;  2E00 A;  3KX1 A;  1PPO A;  1MEM A;  2HHN A;  2C0Y A;  1YAL A;  4W4U A;  1XKG A;  4CDC B;  3V6E A; 
#chains in the Genus database with same CATH topology
 1NLJ A;  4YYU A;  1SNK A;  2WBF X;  1EWP A;  1TLO A;  1YK7 A;  2NQI A;  3MP2 A;  4D8B A;  3OF9 A;  1U9W A;  1POP A;  4OEL A;  1MDW A;  2R9C A;  1AU0 A;  4PAD A;  4RNA A;  1CJL A;  1K3B B;  2PNS A;  3RVX A;  2FRA A;  3P5U A;  2PBH A;  4PP1 A;  3TMP A;  4I05 A;  2Y5B A;  1CS8 A;  3C0R A;  1IWD A;  1PAD A;  3OIS A;  2AIM A;  4M0W A;  2XU5 A;  2XU4 A;  3H7D A;  5CVM A;  2HD5 A;  2AUZ A;  4RY2 A;  4W5C A;  3OQC A;  1F2C A;  2GFO A;  3PBH A;  3V6E A;  1QDQ A;  5JH3 A;  3BB7 A;  2ARY A;  2DJF B;  3AI8 A;  4Q8H A;  3TRK A;  1TU6 A;  3TNX A;  1GCB A;  4D8I A;  3O0U A;  2E02 A;  3F75 A;  4X6H A;  1THE A;  3B79 A;  4W5B A;  3F5V A;  5EGW A;  1AU2 A;  1NB5 A;  4DMY A;  3BC3 A;  3BCN A;  1CVZ A;  3PHX A;  5A24 A;  2B1M A;  2DC9 A;  4MSX A;  3PSE A;  1UKF A;  6PAD A;  4P6E A;  3N3G A;  2E01 A;  3KWZ A;  3ZNH A;  4Q8G A;  1KHQ A;  1ICF A;  1ITO A;  1PXV A;  1A6R A;  2FYE A;  4PT5 A;  1AYV A;  2AGA A;  2DCC A;  5JA7 A;  2BTW B;  4CDD B;  4CDF B;  5PAD A;  4PI3 A;  1YVB A;  3BPF A;  4FK5 A;  3WXG A;  1CB5 A;  2GHU A;  1QXP A;  3MTV A;  5E6J A;  4PP2 E;  1Y4H A;  4BPV A;  4XZX A;  2NQG A;  4YYV A;  2AU1 A;  2AYN A;  2BU3 A;  2DCD A;  4P16 A;  1Y08 A;  1AU3 A;  4WA6 A;  2DCA A;  1EWO A;  1VJV A;  1BY8 A;  4I07 A;  1TL9 A;  2VHF A;  3IEJ A;  1U9X A;  3H8C A;  3LXS A;  4QBB A;  3ZUA A;  1NQC A;  3W31 A;  1O0E A;  2FUD A;  2AVW A;  1PIP A;  1JQP A;  2CB5 A;  2HH5 A;  3H8B A;  3CBJ A;  1VSN A;  3PW3 A;  5F02 A;  2P86 A;  3HHI A;  3MHS A;  4HWY A;  2BDZ A;  4QRV A;  4OVZ B;  1DF0 A;  2PRE A;  3BBA A;  3QJ3 A;  2FE8 A;  1ME3 A;  3O1G A;  2E03 A;  1EF7 A;  2DJG B;  4I04 A;  3S3Q A;  4RF1 A;  1PE6 A;  2H7J A;  2P7U A;  2NQA A;  2JQG R;  1DKI A;  2FT2 A;  3RVW A;  4G54 A;  4CZW A;  1Q6K A;  3N4C A;  1AU4 A;  2FO5 A;  1CV8 A;  2XU1 A;  3MOR A;  3DF0 A;  4D8E A;  3MTN A;  4AXM A;  3PNR A;  1F2A A;  1BGO A;  2YJ8 A;  3MHH A;  2IPP B;  4MM3 B;  2ATO A;  3IOQ A;  3HHA A;  2PAD A;  4BS5 A;  2DZY A;  1EWM A;  4YV8 A;  1KHP A;  2FQ9 A;  4RKX A;  3E9S A;  2G7Y A;  3HWN A;  2B1N A;  1U9Q X;  1STF E;  2UZJ A;  2AUX A;  3S3R A;  1NB3 A;  5J94 A;  4KLB A;  3USV A;  3I3T A;  4REZ A;  2FTD A;  2FRQ A;  1X9Y A;  4IP3 A;  4K7C A;  3KWB X;  2DZZ A;  5CHV A;  2JTC A;  3KKU A;  4X6J A;  2DC8 A;  3B21 A;  1HUC B;  4CDE B;  1ZIV A;  2R9F A;  3V6C A;  4FJC A;  4BOS A;  5K16 A;  4AXL A;  5EZS A;  1F2B A;  3H89 A;  4BOP A;  4FIP A;  4ZTB A;  9PAP A;  4DMX A;  2F7D A;  4HXD B;  1KFU L;  2JQF R;  3E1Z B;  1FH0 A;  1QMY A;  4XR7 A;  3N3K A;  4N79 A;  2YJC A;  1MEG A;  2OZ2 A;  3PRP A;  4BOQ A;  4OW0 A;  1BP4 A;  3WXE A;  1S4V A;  4P6G A;  4IUM A;  1PCI A;  1AYW A;  2Z84 A;  1YK8 A;  4A5U A;  3H6S A;  3IMA A;  3RNV A;  3P5V A;  2OP3 A;  2DCB A;  4GUA A;  5EZQ A;  1U5I A;  1NL6 A;  3O65 A;  1BQI A;  3PT2 A;  3K24 A;  3C9E A;  3IHP A;  1AYU A;  2P0R A;  1KFX L;  2R6N A;  2YJ2 A;  2YJ9 A;  3ERV A;  1SP4 B;  2R9M A;  3QT4 A;  2G8J A;  4YYR A;  4QRX A;  2DC7 A;  3IV2 A;  5CVO B;  5JZE A;  1F29 A;  3OF8 A;  3IFU A;  4MI7 A;  4YYQ A;  3CBK A;  1M6D A;  3M99 A;  7PCK A;  5CVN B;  3BY4 A;  2AYO A;  2DC6 A;  2AS8 A;  2O6X A;  2R9O A;  3CH2 X;  1PPD A;  4XUI A;  2HWK A;  3MJ5 A;  3KFQ A;  3GCB A;  1CTE A;  3QSD A;  1ME4 A;  3KSE A;  3P5X A;  2VHS A;  4BOZ A;  3K8U A;  4BQV A;  2G8E A;  1MHW A;  4ZUX U;  1MS6 A;  4QH6 A;  3NHE A;  3OVZ A;  4WUR A;  1CPJ A;  2R9N A;  1GEC E;  4OEM A;  2G6D A;  3RVV A;  1NPZ A;  1CQD A;  1GLO A;  2BDL A;  2HXZ A;  3OVX A;  3U8E A;  2F1G A;  4BS6 A;  2JRI A;  4QRG A;  4X6I A;  2J7Q A;  3LFY A;  3BWK A;  2BTW A;  3I06 A;  1QOL A;  1CSB B;  4N4Z A;  1ZCM A;  8PCH A;  4YYW A;  2XU3 A;  5CHT A;  1MIR A;  1PBH A;  1KXR A;  1PPN A;  1ATK A;  3P5W A;  2IBI A;  3IUT A;  3BOW A;  2J7Q C;  1PVJ A;  2OUL A;  3CH3 X;  3PDF A;  3PHW A;  2Y6E A;  1PPP A;  3WXF A;  4BSQ A;  2YJB A;  4MZS A;  4YVA A;  1YT7 A;  1GMY A;  4YYS A;  3PRM A;  1EWL A;  4RF0 A;  3K9M A;  1DEU A;  2ACT A;  4BOU A;  3HD3 A;  4N8W A;  1U9V A;  2CIO A;  2NQD B;  4MZO A;  5EF4 A;  5FPW A;  1AEC A;  3BPM A;  1AIM A;  3D6S A;  3KW9 A;  5KO3 A;  2E00 A;  3KX1 A;  1PPO A;  4OVZ A;  3PHU A;  1MEM A;  2HHN A;  4R3D A;  2C0Y A;  2DOS A;  3W30 A;  1YAL A;  4W4U A;  1XKG A;  4CDC B;  1YZB A; 
#chains in the Genus database with same CATH homology
 1NLJ A;  4YYU A;  1SNK A;  2WBF X;  1EWP A;  1TLO A;  1YK7 A;  2NQI A;  3OF9 A;  1U9W A;  1POP A;  4OEL A;  1MDW A;  2R9C A;  1AU0 A;  4PAD A;  1CJL A;  1K3B B;  2PNS A;  3D9W A;  2FRA A;  3RVX A;  2VFC A;  3P5U A;  2PBH A;  4PP1 A;  4I05 A;  2Y5B A;  1CS8 A;  1W4T A;  1IWD A;  1PAD A;  3OIS A;  2AIM A;  2XU5 A;  2XU4 A;  3H7D A;  5CVM A;  2HD5 A;  2AUZ A;  4RY2 A;  4W5C A;  1F2C A;  2GFO A;  3PBH A;  1QDQ A;  5JH3 A;  2ARY A;  2DJF B;  3AI8 A;  4Q8H A;  1TU6 A;  3TNX A;  1GCB A;  3O0U A;  2E02 A;  3F75 A;  4X6H A;  1THE A;  3B79 A;  4W5B A;  3F5V A;  5EGW A;  1AU2 A;  1NB5 A;  4DMY A;  3BC3 A;  3BCN A;  1CVZ A;  5A24 A;  2B1M A;  2DC9 A;  4MSX A;  4B55 A;  6PAD A;  4P6E A;  3N3G A;  2E01 A;  3KWZ A;  4Q8G A;  1KHQ A;  1ICF A;  1ITO A;  1PXV A;  1A6R A;  2BSZ A;  2FYE A;  1AYV A;  2DCC A;  5JA7 A;  4GUZ A;  4CDD B;  4CDF B;  5PAD A;  4PI3 A;  1YVB A;  3BPF A;  4FK5 A;  3WXG A;  1CB5 A;  2GHU A;  1QXP A;  4PP2 E;  1Y4H A;  4BPV A;  2NQG A;  4YYV A;  2AU1 A;  2AYN A;  2DCD A;  1Y08 A;  1AU3 A;  4WA6 A;  2DCA A;  1EWO A;  1VJV A;  1BY8 A;  4I07 A;  1TL9 A;  2VHF A;  3IEJ A;  1U9X A;  3H8C A;  3LXS A;  4QBB A;  3ZUA A;  1NQC A;  1O0E A;  2FUD A;  2AVW A;  1PIP A;  1JQP A;  2CB5 A;  2HH5 A;  3H8B A;  3CBJ A;  1VSN A;  3PW3 A;  5F02 A;  2P86 A;  3HHI A;  3MHS A;  4HWY A;  2BDZ A;  4QRV A;  1DF0 A;  2PRE A;  3QJ3 A;  1ME3 A;  3O1G A;  2E03 A;  1EF7 A;  2DJG B;  4I04 A;  3S3Q A;  1PE6 A;  2H7J A;  2P7U A;  2NQA A;  2JQG R;  2FT2 A;  3RVW A;  4G54 A;  4CZW A;  1Q6K A;  3N4C A;  1AU4 A;  2FO5 A;  1CV8 A;  2XU1 A;  3MOR A;  3DF0 A;  3MTN A;  4AXM A;  3PNR A;  1F2A A;  1BGO A;  2YJ8 A;  1GX3 A;  3MHH A;  2IPP B;  2ATO A;  3IOQ A;  3HHA A;  2PAD A;  4BS5 A;  2DZY A;  1EWM A;  1W6F A;  4YV8 A;  1KHP A;  2FQ9 A;  2G7Y A;  3HWN A;  2B1N A;  1U9Q X;  1STF E;  2AUX A;  3S3R A;  1NB3 A;  5J94 A;  4KLB A;  3USV A;  3I3T A;  2FTD A;  2FRQ A;  1X9Y A;  4K7C A;  3KWB X;  2DZZ A;  5CHV A;  3KKU A;  4X6J A;  2DC8 A;  1HUC B;  4CDE B;  1ZIV A;  2R9F A;  3V6C A;  4FJC A;  5K16 A;  4AXL A;  1F2B A;  3H89 A;  4FIP A;  9PAP A;  4DMX A;  2F7D A;  1KFU L;  2JQF R;  3E1Z B;  1FH0 A;  1QMY A;  4XR7 A;  3N3K A;  4N79 A;  2YJC A;  1MEG A;  2OZ2 A;  1BP4 A;  3WXE A;  4BGF A;  1S4V A;  4P6G A;  1PCI A;  1AYW A;  1YK8 A;  3H6S A;  3IMA A;  4NV8 A;  3P5V A;  2OP3 A;  2DCB A;  1U5I A;  1NL6 A;  1BQI A;  3LTW A;  3K24 A;  3C9E A;  3IHP A;  1AYU A;  2P0R A;  1KFX L;  2R6N A;  2YJ2 A;  2YJ9 A;  3ERV A;  1SP4 B;  2R9M A;  3QT4 A;  2G8J A;  4YYR A;  4QRX A;  2DC7 A;  3IV2 A;  5CVO B;  1F29 A;  3OF8 A;  4YYQ A;  3CBK A;  1M6D A;  3M99 A;  7PCK A;  5CVN B;  2AYO A;  2DC6 A;  2AS8 A;  2O6X A;  2R9O A;  3CH2 X;  1PPD A;  4XUI A;  3KFQ A;  3GCB A;  1CTE A;  3QSD A;  1ME4 A;  1E2T A;  3KSE A;  3P5X A;  2VHS A;  3K8U A;  4BQV A;  2G8E A;  1MHW A;  4ZUX U;  1MS6 A;  4QH6 A;  3NHE A;  3OVZ A;  4C5P A;  1CPJ A;  2R9N A;  1GEC E;  4OEM A;  2G6D A;  3RVV A;  1NPZ A;  1CQD A;  1GLO A;  2BDL A;  2HXZ A;  3OVX A;  3U8E A;  2F1G A;  4BS6 A;  4QRG A;  4X6I A;  3LFY A;  3BWK A;  3I06 A;  1QOL A;  1CSB B;  4N4Z A;  1ZCM A;  8PCH A;  4YYW A;  2XU3 A;  5CHT A;  1MIR A;  1PBH A;  1KXR A;  1PPN A;  1ATK A;  3P5W A;  2IBI A;  3IUT A;  3BOW A;  2OUL A;  3CH3 X;  3PDF A;  2Y6E A;  1PPP A;  3WXF A;  4BSQ A;  2YJB A;  4MZS A;  4YVA A;  1YT7 A;  1GMY A;  4YYS A;  1EWL A;  3K9M A;  1DEU A;  2ACT A;  3HD3 A;  4N8W A;  1U9V A;  2CIO A;  2NQD B;  4MZO A;  5EF4 A;  5FPW A;  1AEC A;  3BPM A;  1AIM A;  4NV7 A;  3D6S A;  3KW9 A;  2E00 A;  3KX1 A;  1PPO A;  1W5R A;  1MEM A;  2HHN A;  2C0Y A;  1YAL A;  2VFB A;  4W4U A;  1XKG A;  4CDC B;  3V6E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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