4I07A

Structure of mature form of cathepsin b1 from schistosoma mansoni
Total Genus 81
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
81
sequence length
253
structure length
252
Chain Sequence
EIPSSFDSRKKWPRCKSIATIRDQSRCGSWAFGAVEAMSDRSCIQSGGKQNVELSAVDLLSCCESCGLGCEGGILGPAWDYWVKEGIVTGSSKENHAGCEPYPFPKCEHHTKGKYPPCGSKIYKTPRCKQTCQKKYKTPYTQDKHRGKSSYNVKNDEKAIQKEIMKYGPVEAGFTVYEDFLNYKSGIYKHITGETLGGHAIRIIGWGVENKAPYWLIANSWNEDWGENGYFRIVRGRDECSIESEVTAGRIN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch
pubmed doi rcsb
molecule tags Hydrolase
source organism Schistosoma mansoni
molecule keywords Cathepsin B-like peptidase (C01 family)
total genus 81
structure length 252
sequence length 253
ec nomenclature ec 3.4.22.1: Cathepsin B.
pdb deposition date 2012-11-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4i07A00
4MZOA 3H6SA 3MHHA 5JA7A 1MEGA 4RY2A 1PPDA 2DC8A 2YJ2A 4BSQA 3H8BA 3C9EA 4YYUA 1KHPA 4N8WA 3USVA 2R9NA 1EWPA 2VHFA 3NHEA 3HHIA 3ERVA 2YJBA 2YJ8A 1POPA 1F2AA 4Q8GA 3N3KA 3BPMA 1NB5A 2Y5BA 1NLJA 3CBKA 2FTDA 1Y4HA 1M6DA 3O0UA 1EWOA 4BS5A 9PAPA 3RVVA 1BY8A 3M99A 2WBFX 3PW3A 3RVWA 1MDWA 2FUDA 3DF0A 5F02A 4W5BA 7PCKA 1Y08A 3PDFA 4AXLA 2C0YA 4PP1A 4X6HA 1U9WA 4XR7A 2AS8A 2E01A 3GCBA 3BPFA 2DC6A 3LFYA 3BC3A 3IHPA 2HD5A 5CHTA 1F29A 2HH5A 4QRVA 4PI3A 5CVNB 2FYEA 3K9MA 4FJCA 2DC7A 4YVAA 4BS6A 1NPZA 5FPWA 1BGOA 4P6GA 2DZZA 2AUZA 4HWYA 2BDZA 3MTNA 3MORA 1AIMA 3BWKA 1U9VA 2CIOA 3I06A 2AVWA 1AU4A 1ATKA 5EGWA 1TL9A 2FT2A 1QOLA 3H89A 1DEUA 4CDCB 2PNSA 4N79A 1GLOA 3WXFA 2R9OA 1AECA 3OF9A 2AYOA 4BQVA 1MIRA 3BOWA 2E02A 5CVOB 2PBHA 4Q8HA 4WA6A 1Q6KA 3H8CA 1F2CA 4QRGA 1GECE 2NQDB 4P6EA 1CVZA 1MEMA 1PPPA 1CB5A 1GCBA 3B79A 1CJLA 2AIMA 4QBBA 3HD3A 4W5CA 4PADA 1CQDA 2R9FA 3D6SA 1BQIA 2R9MA 3P5UA 3V6EA 2R9CA 1QXPA 2IPPB 3WXGA 3PNRA 5J94A 2NQAA 2NQIA 3OF8A 1BP4A 4N4ZA 4MSXA 1SP4B 1ZCMA 3MHSA 4CZWA 3RVXA 1FH0A 3AI8A 1KXRA 2E03A 1PE6A 1U9XA 3BCNA 2R6NA 1MS6A 2DZYA 2CB5A 2G8EA 1QDQA 3HWNA 5CVMA 4CDDB 3P5XA 2OULA 1U9QX 4K7CA 2P86A 1ITOA 1YVBA 3OVXA 1STFE 1TLOA 1PXVA 1DF0A 1U5IA 4I05A 3KFQA 3IUTA 1XKGA 3S3RA 1A6RA 2HXZA 1K3BB 8PCHA 2FRAA 3IV2A 1AU2A 4KLBA 1PIPA 4X6JA 4ZUXU 1PPOA 3N4CA 4XUIA 1YT7A 2AU1A 2DJGB 3KKUA 3CBJA 1CV8A 2PADA 1HUCB 2DC9A 3CH2X 2H7JA 3PBHA 1AYVA 2XU1A 1AU3A 2DCBA 4YYSA 3IMAA 2PREA 3O1GA 2G8JA 3OISA 2DCDA 2XU5A 1AYWA 3E1ZB 2P7UA 3U8EA 4DMXA 3I3TA 4YV8A 1EF7A 1PCIA 1ZIVA 1VJVA 4YYWA 2DCAA 2G6DA 2FO5A 4I07A 3F75A 3TNXA 2AUXA 2B1NA 2ATOA 4AXMA 2E00A 1THEA 1SNKA 3KW9A 3QJ3A 1PPNA 1IWDA 5EF4A 2FRQA 1CS8A 4FK5A 2DCCA 2G7YA 1ME3A 4OELA 3CH3X 1AYUA 3N3GA 4BPVA 1EWLA 3H7DA 2YJCA 3IOQA 3HHAA 2Y6EA 5PADA 1PADA 3K24A 2VHSA 2HHNA 6PADA 3KSEA 2XU4A 5A24A 5JH3A 1GMYA 4YYVA 5K16A 1PBHA 1KHQA 1JQPA 3LXSA 2BDLA 3IEJA 4DMYA 4OEMA 1TU6A 1ICFA 2OP3A 2JQGR 4QRXA 3KWBX 2ARYA 4CDFB 2IBIA 3V6CA 4I04A 2GFOA 1NQCA 2XU3A 3K8UA 2JQFR 4W4UA 2NQGA 4G54A 2DJFB 3P5VA 2P0RA 1S4VA 2F7DA 2F1GA 1CTEA 3QSDA 3OVZA 4FIPA 2FQ9A 1MHWA 1YALA 3WXEA 3F5VA 3ZUAA 1O0EA 3KWZA 1KFXL 2GHUA 1F2BA 1QMYA 3KX1A 5CHVA 4X6IA 4MZSA 4PP2E 1NL6A 2ACTA 1NB3A 3S3QA 1ME4A 4QH6A 1CPJA 1EWMA 3QT4A 2O6XA 1AU0A 4YYQA 1YK7A 2AYNA 2OZ2A 4YYRA 4CDEB 1X9YA 1YK8A 1VSNA 1KFUL 1CSBB 2B1MA 2YJ9A 3P5WA
chains in the Genus database with same CATH superfamily
4MZOA 3H6SA 2JRIA 3MHHA 5JA7A 1MEGA 4RY2A 1PPDA 2DC8A 2YJ2A 3C0RA 4BSQA 3H8BA 3C9EA 4YYUA 1KHPA 4N8WA 3USVA 2R9NA 1EWPA 2VHFA 2BTWA 3NHEA 3HHIA 3ERVA 2YJBA 2YJ8A 1POPA 1F2AA 4Q8GA 3N3KA 3BPMA 4BOUA 1NB5A 2Y5BA 3W30A 1NLJA 3CBKA 2FTDA 1Y4HA 4MI7A 1M6DA 3O0UA 3PHUA 1EWOA 4BS5A 9PAPA 3RVVA 1BY8A 3O65A 3M99A 4XZXA 2WBFX 3PW3A 3RVWA 1MDWA 3PRPA 2FUDA 3DF0A 5F02A 4W5BA 3TRKA 7PCKA 1Y08A 3PDFA 4P16A 4AXLA 2C0YA 3BBAA 4PP1A 4X6HA 1U9WA 4XR7A 5EZQA 2AS8A 2E01A 3GCBA 4M0WA 2FE8A 4RNAA 3B21A 3BPFA 2DC6A 3LFYA 3BC3A 3IHPA 2HD5A 5CHTA 1F29A 2HH5A 4QRVA 4PI3A 4OW0A 5CVNB 2FYEA 1YZBA 3K9MA 4FJCA 2DC7A 3PRMA 4YVAA 4BS6A 1NPZA 5FPWA 1BGOA 2DZZA 4P6GA 2AUZA 4HWYA 1DKIA 4OVZA 2BDZA 3MTNA 3MORA 4A5UA 1AIMA 3BWKA 1U9VA 2CIOA 3I06A 2AVWA 1AU4A 1ATKA 5EGWA 2AGAA 1TL9A 4IP3A 2FT2A 1QOLA 3H89A 1DEUA 4CDCB 2PNSA 4N79A 1GLOA 3WXFA 2BTWB 2R9OA 1AECA 3OF9A 2AYOA 4BQVA 1MIRA 3BOWA 2E02A 5CVOB 2PBHA 4HXDB 4WA6A 4Q8HA 1Q6KA 3H8CA 1F2CA 4QRGA 1GECE 2NQDB 5EZSA 4P6EA 3TMPA 1CVZA 1MEMA 1PPPA 1CB5A 1GCBA 3B79A 3PSEA 1CJLA 2AIMA 4QBBA 3HD3A 4W5CA 4PADA 1CQDA 2R9FA 2J7QC 3D6SA 1BQIA 2R9MA 3P5UA 3V6EA 2R9CA 1QXPA 2IPPB 3WXGA 4BOPA 3PNRA 5J94A 2NQAA 2NQIA 3OF8A 1BP4A 3ZNHA 4N4ZA 4MSXA 1SP4B 1ZCMA 3MHSA 4CZWA 3RVXA 1FH0A 3AI8A 1KXRA 3PT2A 2E03A 1PE6A 1U9XA 3BCNA 2DOSA 2R6NA 4ZTBA 1MS6A 2DZYA 2CB5A 2G8EA 1QDQA 3HWNA 5CVMA 4CDDB 3P5XA 2OULA 1U9QX 4K7CA 2P86A 1ITOA 1YVBA 3OVXA 1STFE 1TLOA 1PXVA 1DF0A 1U5IA 4I05A 3KFQA 3IUTA 1XKGA 3S3RA 2UZJA 1A6RA 2HXZA 1K3BB 3W31A 8PCHA 4OVZB 2FRAA 3IV2A 4IUMA 1AU2A 4KLBA 1PIPA 4X6JA 4BOSA 4ZUXU 1PPOA 3N4CA 4XUIA 1YT7A 2AU1A 2DJGB 3KKUA 3CBJA 1CV8A 2PADA 1HUCB 2DC9A 3OQCA 3CH2X 2H7JA 3PBHA 1AYVA 2XU1A 1AU3A 2DCBA 4YYSA 3IMAA 2PREA 3O1GA 2G8JA 3OISA 2DCDA 2XU5A 1AYWA 3E1ZB 2P7UA 3U8EA 4WURA 4DMXA 4RF0A 3I3TA 4YV8A 1EF7A 1PCIA 1ZIVA 1VJVA 4YYWA 2DCAA 2G6DA 2FO5A 3PHWA 4I07A 3F75A 3TNXA 2AUXA 2B1NA 2ATOA 4AXMA 4BOZA 1UKFA 2E00A 1THEA 1SNKA 3KW9A 3QJ3A 5KO3A 4PT5A 1PPNA 1IWDA 5EF4A 2FRQA 1CS8A 3E9SA 4FK5A 2DCCA 2G7YA 4BOQA 1ME3A 4OELA 3CH3X 4D8IA 1AYUA 3N3GA 2J7QA 4BPVA 1EWLA 3H7DA 2YJCA 3IOQA 3HHAA 2Y6EA 3MP2A 5PADA 1PADA 3K24A 2VHSA 3IFUA 2HHNA 4RKXA 6PADA 3KSEA 2XU4A 5A24A 5JH3A 1GMYA 4YYVA 5K16A 1PBHA 1KHQA 1JQPA 3LXSA 2BDLA 3IEJA 4DMYA 4OEMA 1TU6A 1ICFA 2OP3A 3MJ5A 2JQGR 4QRXA 3KWBX 3MTVA 2ARYA 4CDFB 2IBIA 3V6CA 4I04A 4R3DA 2GFOA 1NQCA 2XU3A 3K8UA 4D8EA 2JQFR 4W4UA 5E6JA 2NQGA 4G54A 2DJFB 3BB7A 3P5VA 1PVJA 2P0RA 1S4VA 2F7DA 2F1GA 1CTEA 3QSDA 3OVZA 2JTCA 4FIPA 2FQ9A 1MHWA 1YALA 3WXEA 4D8BA 3F5VA 3ZUAA 1O0EA 2BU3A 2HWKA 3KWZA 1KFXL 2Z84A 2GHUA 1F2BA 1QMYA 3KX1A 3PHXA 3RNVA 5CHVA 4X6IA 4MZSA 4PP2E 1NL6A 2ACTA 1NB3A 3S3QA 1ME4A 4QH6A 1CPJA 1EWMA 3QT4A 2O6XA 1AU0A 5JZEA 4YYQA 1YK7A 2AYNA 2OZ2A 4RF1A 4YYRA 4CDEB 4REZA 1X9YA 1YK8A 4MM3B 1VSNA 3BY4A 1KFUL 1CSBB 2B1MA 2YJ9A 4GUAA 3P5WA
chains in the Genus database with same CATH topology
4MZOA 3H6SA 3MHHA 5JA7A 1MEGA 4RY2A 1PPDA 2DC8A 2YJ2A 4BSQA 3H8BA 3C9EA 4YYUA 1KHPA 4N8WA 3USVA 2R9NA 1EWPA 4GUZA 2VHFA 3NHEA 3HHIA 3ERVA 2YJBA 2YJ8A 1POPA 1F2AA 4Q8GA 3N3KA 3BPMA 1NB5A 2Y5BA 1NLJA 3CBKA 2FTDA 4C5PA 1Y4HA 1M6DA 3O0UA 1EWOA 4BS5A 1W5RA 9PAPA 3RVVA 1BY8A 3M99A 2WBFX 3PW3A 3RVWA 1MDWA 2FUDA 3DF0A 5F02A 4W5BA 7PCKA 1Y08A 3PDFA 4AXLA 2C0YA 4PP1A 4X6HA 1U9WA 2VFCA 4XR7A 2AS8A 2E01A 3GCBA 3BPFA 2DC6A 3LFYA 3BC3A 3IHPA 2HD5A 5CHTA 1F29A 2HH5A 4QRVA 4PI3A 5CVNB 2FYEA 3K9MA 4FJCA 2DC7A 4YVAA 4BS6A 1NPZA 5FPWA 1BGOA 2DZZA 4P6GA 2AUZA 4HWYA 2BDZA 3MTNA 3MORA 1AIMA 3BWKA 1E2TA 1U9VA 2CIOA 3I06A 2AVWA 1AU4A 1ATKA 5EGWA 1TL9A 2FT2A 1QOLA 3H89A 1DEUA 4CDCB 2PNSA 4N79A 1GLOA 3WXFA 2R9OA 1AECA 3OF9A 2AYOA 4BQVA 1MIRA 3BOWA 2E02A 5CVOB 2PBHA 4Q8HA 4WA6A 1Q6KA 3H8CA 1F2CA 4QRGA 1GECE 2NQDB 4P6EA 1CVZA 1MEMA 1PPPA 1CB5A 1GCBA 1W6FA 3B79A 1CJLA 2AIMA 4QBBA 3HD3A 4W5CA 4PADA 1CQDA 2R9FA 3D6SA 1BQIA 2R9MA 3P5UA 2VFBA 3V6EA 2R9CA 1QXPA 2IPPB 3WXGA 3PNRA 5J94A 2NQAA 2NQIA 3OF8A 1BP4A 4N4ZA 4MSXA 1SP4B 1ZCMA 3MHSA 4BGFA 4CZWA 3RVXA 1FH0A 3AI8A 1KXRA 2E03A 1PE6A 1U9XA 3BCNA 2R6NA 1MS6A 2DZYA 2CB5A 2G8EA 1QDQA 3HWNA 5CVMA 4CDDB 3P5XA 2OULA 1U9QX 4K7CA 2P86A 1ITOA 1YVBA 3OVXA 1STFE 1TLOA 1PXVA 3D9WA 1DF0A 1U5IA 4I05A 3KFQA 3IUTA 1XKGA 3S3RA 1A6RA 2HXZA 1K3BB 1GX3A 8PCHA 2FRAA 3IV2A 1AU2A 4KLBA 1PIPA 4X6JA 4ZUXU 1PPOA 3N4CA 4XUIA 1YT7A 2AU1A 2DJGB 3KKUA 3CBJA 1CV8A 3LTWA 2PADA 1HUCB 2DC9A 3CH2X 2H7JA 3PBHA 1AYVA 2XU1A 1AU3A 2DCBA 4YYSA 3IMAA 2PREA 3O1GA 2G8JA 3OISA 2DCDA 2XU5A 1AYWA 3E1ZB 2P7UA 3U8EA 4DMXA 3I3TA 4YV8A 1EF7A 1PCIA 1ZIVA 1VJVA 4YYWA 2DCAA 2G6DA 2FO5A 4I07A 3F75A 3TNXA 2AUXA 2B1NA 2ATOA 4AXMA 2E00A 1THEA 1SNKA 3KW9A 3QJ3A 4B55A 1PPNA 1IWDA 5EF4A 2FRQA 1CS8A 4FK5A 2DCCA 2G7YA 1ME3A 4OELA 3CH3X 1AYUA 3N3GA 4BPVA 1EWLA 3H7DA 2YJCA 3IOQA 3HHAA 2Y6EA 5PADA 1PADA 3K24A 2VHSA 2HHNA 6PADA 3KSEA 2XU4A 5A24A 5JH3A 1GMYA 4YYVA 5K16A 1PBHA 1KHQA 1JQPA 3LXSA 2BDLA 3IEJA 4DMYA 4OEMA 1TU6A 1ICFA 2OP3A 2JQGR 4QRXA 3KWBX 2ARYA 4CDFB 2IBIA 3V6CA 4I04A 2GFOA 1NQCA 2XU3A 3K8UA 4NV7A 2JQFR 4W4UA 2NQGA 4G54A 2DJFB 3P5VA 2BSZA 2P0RA 1W4TA 1S4VA 2F7DA 2F1GA 1CTEA 3QSDA 3OVZA 4FIPA 2FQ9A 1MHWA 1YALA 4NV8A 3WXEA 3F5VA 3ZUAA 1O0EA 3KWZA 1KFXL 2GHUA 1F2BA 1QMYA 3KX1A 5CHVA 4X6IA 4MZSA 4PP2E 1NL6A 2ACTA 1NB3A 3S3QA 1ME4A 4QH6A 1CPJA 1EWMA 3QT4A 2O6XA 1AU0A 4YYQA 1YK7A 2AYNA 2OZ2A 4YYRA 4CDEB 1X9YA 1YK8A 1VSNA 1KFUL 1CSBB 2B1MA 2YJ9A 3P5WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MZO A;  3H6S A;  3MHH A;  5JA7 A;  1MEG A;  4RY2 A;  1PPD A;  2DC8 A;  2YJ2 A;  4BSQ A;  3H8B A;  3C9E A;  4YYU A;  1KHP A;  4N8W A;  3USV A;  2R9N A;  1EWP A;  2VHF A;  3NHE A;  3HHI A;  3ERV A;  2YJB A;  2YJ8 A;  1POP A;  1F2A A;  4Q8G A;  3N3K A;  3BPM A;  1NB5 A;  2Y5B A;  1NLJ A;  3CBK A;  2FTD A;  1Y4H A;  1M6D A;  3O0U A;  1EWO A;  4BS5 A;  9PAP A;  3RVV A;  1BY8 A;  3M99 A;  2WBF X;  3PW3 A;  3RVW A;  1MDW A;  2FUD A;  3DF0 A;  5F02 A;  4W5B A;  7PCK A;  1Y08 A;  3PDF A;  4AXL A;  2C0Y A;  4PP1 A;  4X6H A;  1U9W A;  4XR7 A;  2AS8 A;  2E01 A;  3GCB A;  3BPF A;  2DC6 A;  3LFY A;  3BC3 A;  3IHP A;  2HD5 A;  5CHT A;  1F29 A;  2HH5 A;  4QRV A;  4PI3 A;  5CVN B;  2FYE A;  3K9M A;  4FJC A;  2DC7 A;  4YVA A;  4BS6 A;  1NPZ A;  5FPW A;  1BGO A;  4P6G A;  2DZZ A;  2AUZ A;  4HWY A;  2BDZ A;  3MTN A;  3MOR A;  1AIM A;  3BWK A;  1U9V A;  2CIO A;  3I06 A;  2AVW A;  1AU4 A;  1ATK A;  5EGW A;  1TL9 A;  2FT2 A;  1QOL A;  3H89 A;  1DEU A;  4CDC B;  2PNS A;  4N79 A;  1GLO A;  3WXF A;  2R9O A;  1AEC A;  3OF9 A;  2AYO A;  4BQV A;  1MIR A;  3BOW A;  2E02 A;  5CVO B;  2PBH A;  4Q8H A;  4WA6 A;  1Q6K A;  3H8C A;  1F2C A;  4QRG A;  1GEC E;  2NQD B;  4P6E A;  1CVZ A;  1MEM A;  1PPP A;  1CB5 A;  1GCB A;  3B79 A;  1CJL A;  2AIM A;  4QBB A;  3HD3 A;  4W5C A;  4PAD A;  1CQD A;  2R9F A;  3D6S A;  1BQI A;  2R9M A;  3P5U A;  3V6E A;  2R9C A;  1QXP A;  2IPP B;  3WXG A;  3PNR A;  5J94 A;  2NQA A;  2NQI A;  3OF8 A;  1BP4 A;  4N4Z A;  4MSX A;  1SP4 B;  1ZCM A;  3MHS A;  4CZW A;  3RVX A;  1FH0 A;  3AI8 A;  1KXR A;  2E03 A;  1PE6 A;  1U9X A;  3BCN A;  2R6N A;  1MS6 A;  2DZY A;  2CB5 A;  2G8E A;  1QDQ A;  3HWN A;  5CVM A;  4CDD B;  3P5X A;  2OUL A;  1U9Q X;  4K7C A;  2P86 A;  1ITO A;  1YVB A;  3OVX A;  1STF E;  1TLO A;  1PXV A;  1DF0 A;  1U5I A;  4I05 A;  3KFQ A;  3IUT A;  1XKG A;  3S3R A;  1A6R A;  2HXZ A;  1K3B B;  8PCH A;  2FRA A;  3IV2 A;  1AU2 A;  4KLB A;  1PIP A;  4X6J A;  4ZUX U;  1PPO A;  3N4C A;  4XUI A;  1YT7 A;  2AU1 A;  2DJG B;  3KKU A;  3CBJ A;  1CV8 A;  2PAD A;  1HUC B;  2DC9 A;  3CH2 X;  2H7J A;  3PBH A;  1AYV A;  2XU1 A;  1AU3 A;  2DCB A;  4YYS A;  3IMA A;  2PRE A;  3O1G A;  2G8J A;  3OIS A;  2DCD A;  2XU5 A;  1AYW A;  3E1Z B;  2P7U A;  3U8E A;  4DMX A;  3I3T A;  4YV8 A;  1EF7 A;  1PCI A;  1ZIV A;  1VJV A;  4YYW A;  2DCA A;  2G6D A;  2FO5 A;  4I07 A;  3F75 A;  3TNX A;  2AUX A;  2B1N A;  2ATO A;  4AXM A;  2E00 A;  1THE A;  1SNK A;  3KW9 A;  3QJ3 A;  1PPN A;  1IWD A;  5EF4 A;  2FRQ A;  1CS8 A;  4FK5 A;  2DCC A;  2G7Y A;  1ME3 A;  4OEL A;  3CH3 X;  1AYU A;  3N3G A;  4BPV A;  1EWL A;  3H7D A;  2YJC A;  3IOQ A;  3HHA A;  2Y6E A;  5PAD A;  1PAD A;  3K24 A;  2VHS A;  2HHN A;  6PAD A;  3KSE A;  2XU4 A;  5A24 A;  5JH3 A;  1GMY A;  4YYV A;  5K16 A;  1PBH A;  1KHQ A;  1JQP A;  3LXS A;  2BDL A;  3IEJ A;  4DMY A;  4OEM A;  1TU6 A;  1ICF A;  2OP3 A;  2JQG R;  4QRX A;  3KWB X;  2ARY A;  4CDF B;  2IBI A;  3V6C A;  4I04 A;  2GFO A;  1NQC A;  2XU3 A;  3K8U A;  2JQF R;  4W4U A;  2NQG A;  4G54 A;  2DJF B;  3P5V A;  2P0R A;  1S4V A;  2F7D A;  2F1G A;  1CTE A;  3QSD A;  3OVZ A;  4FIP A;  2FQ9 A;  1MHW A;  1YAL A;  3WXE A;  3F5V A;  3ZUA A;  1O0E A;  3KWZ A;  1KFX L;  2GHU A;  1F2B A;  1QMY A;  3KX1 A;  5CHV A;  4X6I A;  4MZS A;  4PP2 E;  1NL6 A;  2ACT A;  1NB3 A;  3S3Q A;  1ME4 A;  4QH6 A;  1CPJ A;  1EWM A;  3QT4 A;  2O6X A;  1AU0 A;  4YYQ A;  1YK7 A;  2AYN A;  2OZ2 A;  4YYR A;  4CDE B;  1X9Y A;  1YK8 A;  1VSN A;  1KFU L;  1CSB B;  2B1M A;  2YJ9 A;  3P5W A; 
#chains in the Genus database with same CATH topology
 4MZO A;  3H6S A;  2JRI A;  3MHH A;  5JA7 A;  1MEG A;  4RY2 A;  1PPD A;  2DC8 A;  2YJ2 A;  3C0R A;  4BSQ A;  3H8B A;  3C9E A;  4YYU A;  1KHP A;  4N8W A;  3USV A;  2R9N A;  1EWP A;  2VHF A;  2BTW A;  3NHE A;  3HHI A;  3ERV A;  2YJB A;  2YJ8 A;  1POP A;  1F2A A;  4Q8G A;  3N3K A;  3BPM A;  4BOU A;  1NB5 A;  2Y5B A;  3W30 A;  1NLJ A;  3CBK A;  2FTD A;  1Y4H A;  4MI7 A;  1M6D A;  3O0U A;  3PHU A;  1EWO A;  4BS5 A;  9PAP A;  3RVV A;  1BY8 A;  3O65 A;  3M99 A;  4XZX A;  2WBF X;  3PW3 A;  3RVW A;  1MDW A;  3PRP A;  2FUD A;  3DF0 A;  5F02 A;  4W5B A;  3TRK A;  7PCK A;  1Y08 A;  3PDF A;  4P16 A;  4AXL A;  2C0Y A;  3BBA A;  4PP1 A;  4X6H A;  1U9W A;  4XR7 A;  5EZQ A;  2AS8 A;  2E01 A;  3GCB A;  4M0W A;  2FE8 A;  4RNA A;  3B21 A;  3BPF A;  2DC6 A;  3LFY A;  3BC3 A;  3IHP A;  2HD5 A;  5CHT A;  1F29 A;  2HH5 A;  4QRV A;  4PI3 A;  4OW0 A;  5CVN B;  2FYE A;  1YZB A;  3K9M A;  4FJC A;  2DC7 A;  3PRM A;  4YVA A;  4BS6 A;  1NPZ A;  5FPW A;  1BGO A;  2DZZ A;  4P6G A;  2AUZ A;  4HWY A;  1DKI A;  4OVZ A;  2BDZ A;  3MTN A;  3MOR A;  4A5U A;  1AIM A;  3BWK A;  1U9V A;  2CIO A;  3I06 A;  2AVW A;  1AU4 A;  1ATK A;  5EGW A;  2AGA A;  1TL9 A;  4IP3 A;  2FT2 A;  1QOL A;  3H89 A;  1DEU A;  4CDC B;  2PNS A;  4N79 A;  1GLO A;  3WXF A;  2BTW B;  2R9O A;  1AEC A;  3OF9 A;  2AYO A;  4BQV A;  1MIR A;  3BOW A;  2E02 A;  5CVO B;  2PBH A;  4HXD B;  4WA6 A;  4Q8H A;  1Q6K A;  3H8C A;  1F2C A;  4QRG A;  1GEC E;  2NQD B;  5EZS A;  4P6E A;  3TMP A;  1CVZ A;  1MEM A;  1PPP A;  1CB5 A;  1GCB A;  3B79 A;  3PSE A;  1CJL A;  2AIM A;  4QBB A;  3HD3 A;  4W5C A;  4PAD A;  1CQD A;  2R9F A;  2J7Q C;  3D6S A;  1BQI A;  2R9M A;  3P5U A;  3V6E A;  2R9C A;  1QXP A;  2IPP B;  3WXG A;  4BOP A;  3PNR A;  5J94 A;  2NQA A;  2NQI A;  3OF8 A;  1BP4 A;  3ZNH A;  4N4Z A;  4MSX A;  1SP4 B;  1ZCM A;  3MHS A;  4CZW A;  3RVX A;  1FH0 A;  3AI8 A;  1KXR A;  3PT2 A;  2E03 A;  1PE6 A;  1U9X A;  3BCN A;  2DOS A;  2R6N A;  4ZTB A;  1MS6 A;  2DZY A;  2CB5 A;  2G8E A;  1QDQ A;  3HWN A;  5CVM A;  4CDD B;  3P5X A;  2OUL A;  1U9Q X;  4K7C A;  2P86 A;  1ITO A;  1YVB A;  3OVX A;  1STF E;  1TLO A;  1PXV A;  1DF0 A;  1U5I A;  4I05 A;  3KFQ A;  3IUT A;  1XKG A;  3S3R A;  2UZJ A;  1A6R A;  2HXZ A;  1K3B B;  3W31 A;  8PCH A;  4OVZ B;  2FRA A;  3IV2 A;  4IUM A;  1AU2 A;  4KLB A;  1PIP A;  4X6J A;  4BOS A;  4ZUX U;  1PPO A;  3N4C A;  4XUI A;  1YT7 A;  2AU1 A;  2DJG B;  3KKU A;  3CBJ A;  1CV8 A;  2PAD A;  1HUC B;  2DC9 A;  3OQC A;  3CH2 X;  2H7J A;  3PBH A;  1AYV A;  2XU1 A;  1AU3 A;  2DCB A;  4YYS A;  3IMA A;  2PRE A;  3O1G A;  2G8J A;  3OIS A;  2DCD A;  2XU5 A;  1AYW A;  3E1Z B;  2P7U A;  3U8E A;  4WUR A;  4DMX A;  4RF0 A;  3I3T A;  4YV8 A;  1EF7 A;  1PCI A;  1ZIV A;  1VJV A;  4YYW A;  2DCA A;  2G6D A;  2FO5 A;  3PHW A;  4I07 A;  3F75 A;  3TNX A;  2AUX A;  2B1N A;  2ATO A;  4AXM A;  4BOZ A;  1UKF A;  2E00 A;  1THE A;  1SNK A;  3KW9 A;  3QJ3 A;  5KO3 A;  4PT5 A;  1PPN A;  1IWD A;  5EF4 A;  2FRQ A;  1CS8 A;  3E9S A;  4FK5 A;  2DCC A;  2G7Y A;  4BOQ A;  1ME3 A;  4OEL A;  3CH3 X;  4D8I A;  1AYU A;  3N3G A;  2J7Q A;  4BPV A;  1EWL A;  3H7D A;  2YJC A;  3IOQ A;  3HHA A;  2Y6E A;  3MP2 A;  5PAD A;  1PAD A;  3K24 A;  2VHS A;  3IFU A;  2HHN A;  4RKX A;  6PAD A;  3KSE A;  2XU4 A;  5A24 A;  5JH3 A;  1GMY A;  4YYV A;  5K16 A;  1PBH A;  1KHQ A;  1JQP A;  3LXS A;  2BDL A;  3IEJ A;  4DMY A;  4OEM A;  1TU6 A;  1ICF A;  2OP3 A;  3MJ5 A;  2JQG R;  4QRX A;  3KWB X;  3MTV A;  2ARY A;  4CDF B;  2IBI A;  3V6C A;  4I04 A;  4R3D A;  2GFO A;  1NQC A;  2XU3 A;  3K8U A;  4D8E A;  2JQF R;  4W4U A;  5E6J A;  2NQG A;  4G54 A;  2DJF B;  3BB7 A;  3P5V A;  1PVJ A;  2P0R A;  1S4V A;  2F7D A;  2F1G A;  1CTE A;  3QSD A;  3OVZ A;  2JTC A;  4FIP A;  2FQ9 A;  1MHW A;  1YAL A;  3WXE A;  4D8B A;  3F5V A;  3ZUA A;  1O0E A;  2BU3 A;  2HWK A;  3KWZ A;  1KFX L;  2Z84 A;  2GHU A;  1F2B A;  1QMY A;  3KX1 A;  3PHX A;  3RNV A;  5CHV A;  4X6I A;  4MZS A;  4PP2 E;  1NL6 A;  2ACT A;  1NB3 A;  3S3Q A;  1ME4 A;  4QH6 A;  1CPJ A;  1EWM A;  3QT4 A;  2O6X A;  1AU0 A;  5JZE A;  4YYQ A;  1YK7 A;  2AYN A;  2OZ2 A;  4RF1 A;  4YYR A;  4CDE B;  4REZ A;  1X9Y A;  1YK8 A;  4MM3 B;  1VSN A;  3BY4 A;  1KFU L;  1CSB B;  2B1M A;  2YJ9 A;  4GUA A;  3P5W A; 
#chains in the Genus database with same CATH homology
 4MZO A;  3H6S A;  3MHH A;  5JA7 A;  1MEG A;  4RY2 A;  1PPD A;  2DC8 A;  2YJ2 A;  4BSQ A;  3H8B A;  3C9E A;  4YYU A;  1KHP A;  4N8W A;  3USV A;  2R9N A;  1EWP A;  4GUZ A;  2VHF A;  3NHE A;  3HHI A;  3ERV A;  2YJB A;  2YJ8 A;  1POP A;  1F2A A;  4Q8G A;  3N3K A;  3BPM A;  1NB5 A;  2Y5B A;  1NLJ A;  3CBK A;  2FTD A;  4C5P A;  1Y4H A;  1M6D A;  3O0U A;  1EWO A;  4BS5 A;  1W5R A;  9PAP A;  3RVV A;  1BY8 A;  3M99 A;  2WBF X;  3PW3 A;  3RVW A;  1MDW A;  2FUD A;  3DF0 A;  5F02 A;  4W5B A;  7PCK A;  1Y08 A;  3PDF A;  4AXL A;  2C0Y A;  4PP1 A;  4X6H A;  1U9W A;  2VFC A;  4XR7 A;  2AS8 A;  2E01 A;  3GCB A;  3BPF A;  2DC6 A;  3LFY A;  3BC3 A;  3IHP A;  2HD5 A;  5CHT A;  1F29 A;  2HH5 A;  4QRV A;  4PI3 A;  5CVN B;  2FYE A;  3K9M A;  4FJC A;  2DC7 A;  4YVA A;  4BS6 A;  1NPZ A;  5FPW A;  1BGO A;  2DZZ A;  4P6G A;  2AUZ A;  4HWY A;  2BDZ A;  3MTN A;  3MOR A;  1AIM A;  3BWK A;  1E2T A;  1U9V A;  2CIO A;  3I06 A;  2AVW A;  1AU4 A;  1ATK A;  5EGW A;  1TL9 A;  2FT2 A;  1QOL A;  3H89 A;  1DEU A;  4CDC B;  2PNS A;  4N79 A;  1GLO A;  3WXF A;  2R9O A;  1AEC A;  3OF9 A;  2AYO A;  4BQV A;  1MIR A;  3BOW A;  2E02 A;  5CVO B;  2PBH A;  4Q8H A;  4WA6 A;  1Q6K A;  3H8C A;  1F2C A;  4QRG A;  1GEC E;  2NQD B;  4P6E A;  1CVZ A;  1MEM A;  1PPP A;  1CB5 A;  1GCB A;  1W6F A;  3B79 A;  1CJL A;  2AIM A;  4QBB A;  3HD3 A;  4W5C A;  4PAD A;  1CQD A;  2R9F A;  3D6S A;  1BQI A;  2R9M A;  3P5U A;  2VFB A;  3V6E A;  2R9C A;  1QXP A;  2IPP B;  3WXG A;  3PNR A;  5J94 A;  2NQA A;  2NQI A;  3OF8 A;  1BP4 A;  4N4Z A;  4MSX A;  1SP4 B;  1ZCM A;  3MHS A;  4BGF A;  4CZW A;  3RVX A;  1FH0 A;  3AI8 A;  1KXR A;  2E03 A;  1PE6 A;  1U9X A;  3BCN A;  2R6N A;  1MS6 A;  2DZY A;  2CB5 A;  2G8E A;  1QDQ A;  3HWN A;  5CVM A;  4CDD B;  3P5X A;  2OUL A;  1U9Q X;  4K7C A;  2P86 A;  1ITO A;  1YVB A;  3OVX A;  1STF E;  1TLO A;  1PXV A;  3D9W A;  1DF0 A;  1U5I A;  4I05 A;  3KFQ A;  3IUT A;  1XKG A;  3S3R A;  1A6R A;  2HXZ A;  1K3B B;  1GX3 A;  8PCH A;  2FRA A;  3IV2 A;  1AU2 A;  4KLB A;  1PIP A;  4X6J A;  4ZUX U;  1PPO A;  3N4C A;  4XUI A;  1YT7 A;  2AU1 A;  2DJG B;  3KKU A;  3CBJ A;  1CV8 A;  3LTW A;  2PAD A;  1HUC B;  2DC9 A;  3CH2 X;  2H7J A;  3PBH A;  1AYV A;  2XU1 A;  1AU3 A;  2DCB A;  4YYS A;  3IMA A;  2PRE A;  3O1G A;  2G8J A;  3OIS A;  2DCD A;  2XU5 A;  1AYW A;  3E1Z B;  2P7U A;  3U8E A;  4DMX A;  3I3T A;  4YV8 A;  1EF7 A;  1PCI A;  1ZIV A;  1VJV A;  4YYW A;  2DCA A;  2G6D A;  2FO5 A;  4I07 A;  3F75 A;  3TNX A;  2AUX A;  2B1N A;  2ATO A;  4AXM A;  2E00 A;  1THE A;  1SNK A;  3KW9 A;  3QJ3 A;  4B55 A;  1PPN A;  1IWD A;  5EF4 A;  2FRQ A;  1CS8 A;  4FK5 A;  2DCC A;  2G7Y A;  1ME3 A;  4OEL A;  3CH3 X;  1AYU A;  3N3G A;  4BPV A;  1EWL A;  3H7D A;  2YJC A;  3IOQ A;  3HHA A;  2Y6E A;  5PAD A;  1PAD A;  3K24 A;  2VHS A;  2HHN A;  6PAD A;  3KSE A;  2XU4 A;  5A24 A;  5JH3 A;  1GMY A;  4YYV A;  5K16 A;  1PBH A;  1KHQ A;  1JQP A;  3LXS A;  2BDL A;  3IEJ A;  4DMY A;  4OEM A;  1TU6 A;  1ICF A;  2OP3 A;  2JQG R;  4QRX A;  3KWB X;  2ARY A;  4CDF B;  2IBI A;  3V6C A;  4I04 A;  2GFO A;  1NQC A;  2XU3 A;  3K8U A;  4NV7 A;  2JQF R;  4W4U A;  2NQG A;  4G54 A;  2DJF B;  3P5V A;  2BSZ A;  2P0R A;  1W4T A;  1S4V A;  2F7D A;  2F1G A;  1CTE A;  3QSD A;  3OVZ A;  4FIP A;  2FQ9 A;  1MHW A;  1YAL A;  4NV8 A;  3WXE A;  3F5V A;  3ZUA A;  1O0E A;  3KWZ A;  1KFX L;  2GHU A;  1F2B A;  1QMY A;  3KX1 A;  5CHV A;  4X6I A;  4MZS A;  4PP2 E;  1NL6 A;  2ACT A;  1NB3 A;  3S3Q A;  1ME4 A;  4QH6 A;  1CPJ A;  1EWM A;  3QT4 A;  2O6X A;  1AU0 A;  4YYQ A;  1YK7 A;  2AYN A;  2OZ2 A;  4YYR A;  4CDE B;  1X9Y A;  1YK8 A;  1VSN A;  1KFU L;  1CSB B;  2B1M A;  2YJ9 A;  3P5W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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