4YV8A

Crystal structure of cathepsin k bound to the covalent inhibitor lichostatinal
Total Genus 65
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
213
structure length
213
Chain Sequence
DSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Affinity Crystallography: A New Approach to Extracting High-Affinity Enzyme Inhibitors from Natural Extracts.
pubmed doi rcsb
molecule tags Hydrolase/inhibitor
source organism Homo sapiens
molecule keywords Cathepsin K
total genus 65
structure length 213
sequence length 213
ec nomenclature ec 3.4.22.38: Cathepsin K.
pdb deposition date 2015-03-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4yv8A00
3HHAA 2ARYA 2VHFA 4BSQA 4YYRA 1U9VA 3USVA 3TNXA 1AYWA 2ACTA 2E01A 1CQDA 8PCHA 1ICFA 2F7DA 1U5IA 4MZSA 4RY2A 4BS6A 2P7UA 4W4UA 3WXGA 1YALA 2BDLA 2DC7A 2G8EA 1KFXL 3C9EA 3DF0A 2FRAA 4I07A 1CV8A 3MHHA 1Y4HA 3PW3A 3RVVA 2GHUA 1BY8A 2DC6A 1M6DA 4FK5A 1PCIA 2HH5A 2E00A 3BPMA 1MEGA 3P5WA 1S4VA 2HD5A 2PBHA 3V6CA 1MS6A 1QMYA 2DCCA 1F2BA 3HWNA 1PPPA 1MIRA 1ZIVA 2P0RA 4QH6A 3RVWA 4PI3A 1PIPA 2DZZA 2OULA 2NQAA 3KFQA 2C0YA 3OF8A 3M99A 2DCBA 2G6DA 3H7DA 3WXEA 4CZWA 5K16A 1CB5A 1EWLA 2B1NA 1DF0A 3BCNA 2YJ9A 2PREA 2F1GA 2DC9A 1MDWA 3BPFA 2XU1A 4PP1A 1IWDA 3MHSA 2R9MA 4N4ZA 2P86A 2PNSA 1KFUL 1NLJA 4CDDB 2GFOA 2AVWA 4OEMA 9PAPA 1PBHA 2YJ8A 3CH3X 1PXVA 4YYSA 4P6EA 3QJ3A 1QXPA 1AU4A 1NB3A 1BGOA 1HUCB 5F02A 3P5VA 1EF7A 3H6SA 2HXZA 4P6GA 1F2CA 3V6EA 1X9YA 4OELA 1Q6KA 3MORA 3I3TA 1ZCMA 3KSEA 1U9XA 2H7JA 3U8EA 1QOLA 4AXLA 4AXMA 3CBJA 2JQGR 4PP2E 3RVXA 3O1GA 3OF9A 1F2AA 2AYOA 1PPDA 1U9WA 5CHTA 1K3BB 4CDCB 3CBKA 2YJCA 2ATOA 1GLOA 2DZYA 1TU6A 4BQVA 1CJLA 1GECE 1ME3A 4FIPA 4YYUA 1KXRA 4W5BA 1VSNA 3GCBA 3MTNA 2B1MA 3H8CA 1NQCA 1XKGA 4MSXA 3BOWA 4QBBA 1YK8A 1EWPA 3N3GA 2R6NA 2BDZA 3IUTA 5CVNB 2VHSA 1JQPA 3BWKA 2WBFX 4YYQA 4WA6A 2G7YA 2FRQA 3IV2A 1AYVA 1AU0A 3BC3A 3B79A 5CVOB 2G8JA 1NL6A 4DMXA 4XUIA 3HHIA 2AS8A 2FUDA 3PDFA 2FO5A 4Q8GA 2R9CA 3O0UA 3IOQA 3H89A 3KKUA 4KLBA 2FYEA 4QRVA 2FT2A 3H8BA 4BPVA 1YT7A 2FQ9A 3S3QA 4DMYA 1CS8A 1ITOA 1EWOA 1PPOA 1AECA 2OP3A 2AUZA 3KWBX 4PADA 1ATKA 3IEJA 3HD3A 3K24A 1BP4A 5CHVA 4YYVA 3OISA 4ZUXU 4HWYA 2R9OA 1GMYA 2JQFR 5PADA 1AU2A 4XR7A 2YJ2A 1TLOA 2E02A 3N3KA 1AIMA 1SP4B 1FH0A 1MHWA 4X6JA 1DEUA 4YV8A 3OVXA 3F75A 1GCBA 3QT4A 3P5UA 4MZOA 2NQGA 2XU4A 2FTDA 1THEA 3NHEA 4Q8HA 2YJBA 4CDEB 6PADA 2NQIA 2IBIA 4YYWA 5EF4A 2DCDA 4YVAA 1YK7A 1SNKA 2AUXA 3PBHA 4X6IA 3P5XA 5J94A 2IPPB 3I06A 4CDFB 1PE6A 1QDQA 1AU3A 3KX1A 1O0EA 3AI8A 4I04A 5A24A 4QRXA 2XU3A 3E1ZB 1YVBA 1NB5A 1KHPA 2CIOA 4N79A 4W5CA 3PNRA 3LFYA 2XU5A 3LXSA 2E03A 2AIMA 1MEMA 3OVZA 4K7CA 3WXFA 1AYUA 5EGWA 1CVZA 1PADA 2PADA 5JA7A 3ZUAA 1CSBB 2OZ2A 4N8WA 3N4CA 3KWZA 3IHPA 1PPNA 5JH3A 2O6XA 2R9FA 1VJVA 1STFE 1CPJA 5FPWA 1KHQA 3ERVA 1ME4A 2AYNA 3CH2X 3QSDA 2DJGB 2NQDB 4FJCA 2CB5A 4QRGA 1F29A 1TL9A 2DJFB 3K9MA 2HHNA 4BS5A 1A6RA 5CVMA 2DCAA 2R9NA 3IMAA 3KW9A 1U9QX 1Y08A 1NPZA 2AU1A 4I05A 2Y6EA 3F5VA 1POPA 4X6HA 1BQIA 1EWMA 1CTEA 2DC8A 3K8UA 3S3RA 2Y5BA 3D6SA 4G54A 7PCKA
chains in the Genus database with same CATH superfamily
3HHAA 2AGAA 2ARYA 4BOPA 2VHFA 4BSQA 4MM3B 4YYRA 1U9VA 3USVA 3MTVA 3TNXA 1AYWA 3PHXA 2ACTA 2E01A 1CQDA 8PCHA 1ICFA 2F7DA 1U5IA 4MZSA 4RY2A 4OW0A 4BS6A 4RF1A 2P7UA 4W4UA 3WXGA 1YALA 2BDLA 2DC7A 2G8EA 1KFXL 3TRKA 3C9EA 3DF0A 2FRAA 4I07A 1CV8A 3PHUA 3MHHA 3OQCA 1Y4HA 3PW3A 3PT2A 2GHUA 3RVVA 4XZXA 1BY8A 2DC6A 2Z84A 1M6DA 4GUAA 4FK5A 1PCIA 2HH5A 2E00A 3BPMA 1MEGA 3P5WA 2JTCA 1S4VA 2HD5A 2PBHA 3V6CA 1MS6A 4IP3A 1QMYA 2DCCA 4D8EA 1F2BA 3HWNA 5JZEA 1PPPA 1MIRA 1ZIVA 2P0RA 4QH6A 3RVWA 4PI3A 1PIPA 2DZZA 2OULA 2NQAA 3KFQA 2C0YA 3OF8A 3M99A 2DCBA 2G6DA 3H7DA 3WXEA 4CZWA 1YZBA 4IUMA 5K16A 1CB5A 1EWLA 2B1NA 1DF0A 2JRIA 3BCNA 2YJ9A 2PREA 4P16A 2F1GA 2DC9A 1MDWA 3BPFA 2XU1A 3B21A 1IWDA 4PP1A 3MHSA 2R9MA 4N4ZA 2P86A 2PNSA 1KFUL 1NLJA 3MJ5A 2GFOA 4CDDB 2AVWA 4OEMA 9PAPA 1PBHA 2YJ8A 3CH3X 1PXVA 4YYSA 4P6EA 3QJ3A 1QXPA 1AU4A 1UKFA 1NB3A 1BGOA 1PVJA 1HUCB 5F02A 3P5VA 1EF7A 3H6SA 2HXZA 4P6GA 1F2CA 3V6EA 1X9YA 4OELA 4OVZB 1Q6KA 3MORA 3I3TA 1ZCMA 3KSEA 1U9XA 2H7JA 3U8EA 1QOLA 4AXLA 4AXMA 3E9SA 3CBJA 2JQGR 4RNAA 4PP2E 3RVXA 3O1GA 3OF9A 1F2AA 2AYOA 3BY4A 1PPDA 1U9WA 5CHTA 2HWKA 3C0RA 1K3BB 4CDCB 4BOUA 3CBKA 2YJCA 2ATOA 4BOSA 1GLOA 2DZYA 1TU6A 4BQVA 1CJLA 1GECE 1ME3A 4FIPA 4YYUA 1KXRA 4W5BA 1VSNA 3GCBA 3MTNA 4RF0A 2B1MA 3BB7A 3H8CA 1NQCA 4D8BA 1XKGA 4MSXA 3BOWA 4QBBA 1YK8A 1EWPA 3N3GA 2R6NA 2BDZA 3IUTA 5CVNB 2VHSA 5KO3A 1JQPA 3BWKA 2WBFX 4YYQA 4WA6A 2G7YA 2FRQA 3IV2A 1AYVA 1AU0A 3BC3A 3B79A 5CVOB 2G8JA 1NL6A 4DMXA 3MP2A 4XUIA 3HHIA 2AS8A 2FUDA 4RKXA 3PDFA 2FO5A 4Q8GA 1DKIA 2R9CA 3O0UA 3IOQA 3H89A 4OVZA 3KKUA 4KLBA 2FYEA 4QRVA 2FT2A 3H8BA 4BPVA 1YT7A 2FQ9A 2J7QC 3RNVA 3S3QA 4DMYA 1CS8A 3PRMA 1ITOA 1EWOA 1PPOA 1AECA 2OP3A 2AUZA 3KWBX 4PADA 1ATKA 3IEJA 3HD3A 3K24A 1BP4A 5CHVA 4YYVA 3OISA 4ZUXU 2R9OA 4HWYA 4HXDB 1GMYA 2JQFR 5PADA 3W30A 1AU2A 4XR7A 4WURA 2YJ2A 1TLOA 2E02A 3N3KA 1AIMA 1SP4B 1FH0A 1MHWA 4X6JA 1DEUA 5EZQA 4YV8A 4A5UA 3OVXA 3F75A 1GCBA 3QT4A 2BTWA 3P5UA 4MZOA 3O65A 2NQGA 2XU4A 2FTDA 1THEA 3NHEA 4Q8HA 2YJBA 4CDEB 6PADA 2NQIA 2IBIA 4YYWA 4M0WA 3ZNHA 5EF4A 2DCDA 4YVAA 1YK7A 5E6JA 1SNKA 2AUXA 3PBHA 4X6IA 4D8IA 3P5XA 5J94A 2IPPB 3I06A 3IFUA 2BU3A 4CDFB 1PE6A 1QDQA 1AU3A 3KX1A 1O0EA 2BTWB 3AI8A 4I04A 3PHWA 5A24A 4QRXA 2XU3A 3E1ZB 1YVBA 1NB5A 1KHPA 2CIOA 4N79A 4W5CA 3PNRA 3BBAA 2XU5A 3LFYA 3LXSA 2E03A 2AIMA 1MEMA 3OVZA 4K7CA 4R3DA 3WXFA 1AYUA 5EGWA 5EZSA 1CVZA 1PADA 2PADA 5JA7A 3ZUAA 4BOZA 1CSBB 2OZ2A 2FE8A 4N8WA 3N4CA 3KWZA 3PRPA 3IHPA 1PPNA 5JH3A 2O6XA 2R9FA 1VJVA 1STFE 1CPJA 5FPWA 1KHQA 4ZTBA 3ERVA 1ME4A 2AYNA 3CH2X 3QSDA 2DJGB 2NQDB 4FJCA 2CB5A 4QRGA 2DOSA 1F29A 1TL9A 2DJFB 3K9MA 2HHNA 4BS5A 1A6RA 5CVMA 2DCAA 2R9NA 4REZA 3IMAA 4BOQA 2UZJA 3KW9A 1U9QX 1Y08A 4PT5A 1NPZA 2AU1A 4I05A 2Y6EA 3F5VA 2J7QA 1POPA 4X6HA 4MI7A 3W31A 1BQIA 1EWMA 1CTEA 2DC8A 3K8UA 3S3RA 3TMPA 3PSEA 2Y5BA 3D6SA 4G54A 7PCKA
chains in the Genus database with same CATH topology
3HHAA 2ARYA 2VFCA 2VHFA 4BSQA 4YYRA 1U9VA 3USVA 3TNXA 1AYWA 2ACTA 4BGFA 2E01A 1CQDA 8PCHA 1ICFA 2F7DA 1U5IA 4MZSA 4RY2A 4BS6A 2P7UA 4W4UA 3WXGA 1YALA 2BDLA 2DC7A 4B55A 2G8EA 1KFXL 3C9EA 3DF0A 2FRAA 4I07A 1CV8A 3MHHA 1Y4HA 3PW3A 3RVVA 2GHUA 1BY8A 2DC6A 4GUZA 1M6DA 4FK5A 1PCIA 2HH5A 2E00A 3BPMA 1MEGA 3P5WA 1S4VA 2HD5A 2PBHA 3V6CA 1MS6A 4C5PA 1QMYA 2DCCA 1F2BA 3HWNA 1PPPA 1MIRA 1ZIVA 2P0RA 4QH6A 3RVWA 4PI3A 1PIPA 2DZZA 2OULA 1W6FA 2NQAA 3KFQA 2C0YA 3OF8A 3M99A 2DCBA 2G6DA 3H7DA 3WXEA 4CZWA 5K16A 1CB5A 1EWLA 2B1NA 1DF0A 3BCNA 2YJ9A 2PREA 2F1GA 2DC9A 1MDWA 3BPFA 2XU1A 4PP1A 1IWDA 3MHSA 2R9MA 1W4TA 4N4ZA 2P86A 2PNSA 1KFUL 1NLJA 4CDDB 2GFOA 2AVWA 4OEMA 9PAPA 1PBHA 2YJ8A 3CH3X 1PXVA 4YYSA 4P6EA 3QJ3A 1QXPA 1AU4A 1NB3A 1BGOA 1HUCB 5F02A 3P5VA 1EF7A 3H6SA 2HXZA 4P6GA 3LTWA 1F2CA 3V6EA 1X9YA 4OELA 1Q6KA 3MORA 3I3TA 1ZCMA 3KSEA 1U9XA 2H7JA 3U8EA 1QOLA 4AXLA 4AXMA 3CBJA 2JQGR 4PP2E 3RVXA 3O1GA 3OF9A 1F2AA 2AYOA 1PPDA 1U9WA 5CHTA 1K3BB 4CDCB 3CBKA 2YJCA 2ATOA 1GLOA 2DZYA 1TU6A 4BQVA 1CJLA 1GECE 4NV8A 1ME3A 1E2TA 2VFBA 4FIPA 4YYUA 1KXRA 4W5BA 1VSNA 3GCBA 3MTNA 2B1MA 3H8CA 1NQCA 1XKGA 4MSXA 3BOWA 4QBBA 1YK8A 1EWPA 3D9WA 3N3GA 2R6NA 2BDZA 3IUTA 5CVNB 4NV7A 2VHSA 1JQPA 1W5RA 3BWKA 2WBFX 4YYQA 4WA6A 2G7YA 2FRQA 3IV2A 1AYVA 1AU0A 3BC3A 3B79A 5CVOB 2G8JA 1NL6A 4DMXA 4XUIA 3HHIA 2AS8A 2FUDA 3PDFA 2FO5A 4Q8GA 2R9CA 3O0UA 3IOQA 3H89A 3KKUA 4KLBA 2FYEA 4QRVA 2FT2A 3H8BA 4BPVA 1YT7A 1GX3A 2FQ9A 3S3QA 4DMYA 1CS8A 1ITOA 1EWOA 1PPOA 1AECA 2OP3A 2AUZA 3KWBX 4PADA 1ATKA 3IEJA 3HD3A 3K24A 1BP4A 5CHVA 4YYVA 3OISA 4ZUXU 4HWYA 2R9OA 1GMYA 2JQFR 5PADA 1AU2A 4XR7A 2YJ2A 1TLOA 2E02A 3N3KA 1AIMA 1SP4B 1FH0A 1MHWA 4X6JA 1DEUA 4YV8A 3OVXA 3F75A 1GCBA 3QT4A 3P5UA 4MZOA 2NQGA 2XU4A 2FTDA 1THEA 3NHEA 4Q8HA 2YJBA 4CDEB 6PADA 2NQIA 2IBIA 4YYWA 5EF4A 2DCDA 4YVAA 1YK7A 1SNKA 2AUXA 3PBHA 4X6IA 3P5XA 5J94A 2IPPB 3I06A 4CDFB 1PE6A 1QDQA 1AU3A 3KX1A 1O0EA 3AI8A 4I04A 5A24A 4QRXA 2XU3A 3E1ZB 1YVBA 1NB5A 1KHPA 2CIOA 4N79A 4W5CA 3PNRA 3LFYA 2XU5A 3LXSA 2E03A 2AIMA 1MEMA 3OVZA 4K7CA 3WXFA 1AYUA 5EGWA 1CVZA 1PADA 2PADA 5JA7A 3ZUAA 1CSBB 2OZ2A 4N8WA 3N4CA 3KWZA 3IHPA 1PPNA 5JH3A 2O6XA 2R9FA 1VJVA 1STFE 2BSZA 1CPJA 5FPWA 1KHQA 3ERVA 1ME4A 2AYNA 3CH2X 3QSDA 2DJGB 2NQDB 4FJCA 2CB5A 4QRGA 1F29A 1TL9A 2DJFB 3K9MA 2HHNA 4BS5A 1A6RA 5CVMA 2DCAA 2R9NA 3IMAA 3KW9A 1U9QX 1Y08A 1NPZA 2AU1A 4I05A 2Y6EA 3F5VA 1POPA 4X6HA 1BQIA 1EWMA 1CTEA 2DC8A 3K8UA 3S3RA 2Y5BA 3D6SA 4G54A 7PCKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HHA A;  2ARY A;  2VHF A;  4BSQ A;  4YYR A;  1U9V A;  3USV A;  3TNX A;  1AYW A;  2ACT A;  2E01 A;  1CQD A;  8PCH A;  1ICF A;  2F7D A;  1U5I A;  4MZS A;  4RY2 A;  4BS6 A;  2P7U A;  4W4U A;  3WXG A;  1YAL A;  2BDL A;  2DC7 A;  2G8E A;  1KFX L;  3C9E A;  3DF0 A;  2FRA A;  4I07 A;  1CV8 A;  3MHH A;  1Y4H A;  3PW3 A;  3RVV A;  2GHU A;  1BY8 A;  2DC6 A;  1M6D A;  4FK5 A;  1PCI A;  2HH5 A;  2E00 A;  3BPM A;  1MEG A;  3P5W A;  1S4V A;  2HD5 A;  2PBH A;  3V6C A;  1MS6 A;  1QMY A;  2DCC A;  1F2B A;  3HWN A;  1PPP A;  1MIR A;  1ZIV A;  2P0R A;  4QH6 A;  3RVW A;  4PI3 A;  1PIP A;  2DZZ A;  2OUL A;  2NQA A;  3KFQ A;  2C0Y A;  3OF8 A;  3M99 A;  2DCB A;  2G6D A;  3H7D A;  3WXE A;  4CZW A;  5K16 A;  1CB5 A;  1EWL A;  2B1N A;  1DF0 A;  3BCN A;  2YJ9 A;  2PRE A;  2F1G A;  2DC9 A;  1MDW A;  3BPF A;  2XU1 A;  4PP1 A;  1IWD A;  3MHS A;  2R9M A;  4N4Z A;  2P86 A;  2PNS A;  1KFU L;  1NLJ A;  4CDD B;  2GFO A;  2AVW A;  4OEM A;  9PAP A;  1PBH A;  2YJ8 A;  3CH3 X;  1PXV A;  4YYS A;  4P6E A;  3QJ3 A;  1QXP A;  1AU4 A;  1NB3 A;  1BGO A;  1HUC B;  5F02 A;  3P5V A;  1EF7 A;  3H6S A;  2HXZ A;  4P6G A;  1F2C A;  3V6E A;  1X9Y A;  4OEL A;  1Q6K A;  3MOR A;  3I3T A;  1ZCM A;  3KSE A;  1U9X A;  2H7J A;  3U8E A;  1QOL A;  4AXL A;  4AXM A;  3CBJ A;  2JQG R;  4PP2 E;  3RVX A;  3O1G A;  3OF9 A;  1F2A A;  2AYO A;  1PPD A;  1U9W A;  5CHT A;  1K3B B;  4CDC B;  3CBK A;  2YJC A;  2ATO A;  1GLO A;  2DZY A;  1TU6 A;  4BQV A;  1CJL A;  1GEC E;  1ME3 A;  4FIP A;  4YYU A;  1KXR A;  4W5B A;  1VSN A;  3GCB A;  3MTN A;  2B1M A;  3H8C A;  1NQC A;  1XKG A;  4MSX A;  3BOW A;  4QBB A;  1YK8 A;  1EWP A;  3N3G A;  2R6N A;  2BDZ A;  3IUT A;  5CVN B;  2VHS A;  1JQP A;  3BWK A;  2WBF X;  4YYQ A;  4WA6 A;  2G7Y A;  2FRQ A;  3IV2 A;  1AYV A;  1AU0 A;  3BC3 A;  3B79 A;  5CVO B;  2G8J A;  1NL6 A;  4DMX A;  4XUI A;  3HHI A;  2AS8 A;  2FUD A;  3PDF A;  2FO5 A;  4Q8G A;  2R9C A;  3O0U A;  3IOQ A;  3H89 A;  3KKU A;  4KLB A;  2FYE A;  4QRV A;  2FT2 A;  3H8B A;  4BPV A;  1YT7 A;  2FQ9 A;  3S3Q A;  4DMY A;  1CS8 A;  1ITO A;  1EWO A;  1PPO A;  1AEC A;  2OP3 A;  2AUZ A;  3KWB X;  4PAD A;  1ATK A;  3IEJ A;  3HD3 A;  3K24 A;  1BP4 A;  5CHV A;  4YYV A;  3OIS A;  4ZUX U;  4HWY A;  2R9O A;  1GMY A;  2JQF R;  5PAD A;  1AU2 A;  4XR7 A;  2YJ2 A;  1TLO A;  2E02 A;  3N3K A;  1AIM A;  1SP4 B;  1FH0 A;  1MHW A;  4X6J A;  1DEU A;  4YV8 A;  3OVX A;  3F75 A;  1GCB A;  3QT4 A;  3P5U A;  4MZO A;  2NQG A;  2XU4 A;  2FTD A;  1THE A;  3NHE A;  4Q8H A;  2YJB A;  4CDE B;  6PAD A;  2NQI A;  2IBI A;  4YYW A;  5EF4 A;  2DCD A;  4YVA A;  1YK7 A;  1SNK A;  2AUX A;  3PBH A;  4X6I A;  3P5X A;  5J94 A;  2IPP B;  3I06 A;  4CDF B;  1PE6 A;  1QDQ A;  1AU3 A;  3KX1 A;  1O0E A;  3AI8 A;  4I04 A;  5A24 A;  4QRX A;  2XU3 A;  3E1Z B;  1YVB A;  1NB5 A;  1KHP A;  2CIO A;  4N79 A;  4W5C A;  3PNR A;  3LFY A;  2XU5 A;  3LXS A;  2E03 A;  2AIM A;  1MEM A;  3OVZ A;  4K7C A;  3WXF A;  1AYU A;  5EGW A;  1CVZ A;  1PAD A;  2PAD A;  5JA7 A;  3ZUA A;  1CSB B;  2OZ2 A;  4N8W A;  3N4C A;  3KWZ A;  3IHP A;  1PPN A;  5JH3 A;  2O6X A;  2R9F A;  1VJV A;  1STF E;  1CPJ A;  5FPW A;  1KHQ A;  3ERV A;  1ME4 A;  2AYN A;  3CH2 X;  3QSD A;  2DJG B;  2NQD B;  4FJC A;  2CB5 A;  4QRG A;  1F29 A;  1TL9 A;  2DJF B;  3K9M A;  2HHN A;  4BS5 A;  1A6R A;  5CVM A;  2DCA A;  2R9N A;  3IMA A;  3KW9 A;  1U9Q X;  1Y08 A;  1NPZ A;  2AU1 A;  4I05 A;  2Y6E A;  3F5V A;  1POP A;  4X6H A;  1BQI A;  1EWM A;  1CTE A;  2DC8 A;  3K8U A;  3S3R A;  2Y5B A;  3D6S A;  4G54 A;  7PCK A; 
#chains in the Genus database with same CATH topology
 3HHA A;  2AGA A;  2ARY A;  4BOP A;  2VHF A;  4BSQ A;  4MM3 B;  4YYR A;  1U9V A;  3USV A;  3MTV A;  3TNX A;  1AYW A;  3PHX A;  2ACT A;  2E01 A;  1CQD A;  8PCH A;  1ICF A;  2F7D A;  1U5I A;  4MZS A;  4RY2 A;  4OW0 A;  4BS6 A;  4RF1 A;  2P7U A;  4W4U A;  3WXG A;  1YAL A;  2BDL A;  2DC7 A;  2G8E A;  1KFX L;  3TRK A;  3C9E A;  3DF0 A;  2FRA A;  4I07 A;  1CV8 A;  3PHU A;  3MHH A;  3OQC A;  1Y4H A;  3PW3 A;  3PT2 A;  2GHU A;  3RVV A;  4XZX A;  1BY8 A;  2DC6 A;  2Z84 A;  1M6D A;  4GUA A;  4FK5 A;  1PCI A;  2HH5 A;  2E00 A;  3BPM A;  1MEG A;  3P5W A;  2JTC A;  1S4V A;  2HD5 A;  2PBH A;  3V6C A;  1MS6 A;  4IP3 A;  1QMY A;  2DCC A;  4D8E A;  1F2B A;  3HWN A;  5JZE A;  1PPP A;  1MIR A;  1ZIV A;  2P0R A;  4QH6 A;  3RVW A;  4PI3 A;  1PIP A;  2DZZ A;  2OUL A;  2NQA A;  3KFQ A;  2C0Y A;  3OF8 A;  3M99 A;  2DCB A;  2G6D A;  3H7D A;  3WXE A;  4CZW A;  1YZB A;  4IUM A;  5K16 A;  1CB5 A;  1EWL A;  2B1N A;  1DF0 A;  2JRI A;  3BCN A;  2YJ9 A;  2PRE A;  4P16 A;  2F1G A;  2DC9 A;  1MDW A;  3BPF A;  2XU1 A;  3B21 A;  1IWD A;  4PP1 A;  3MHS A;  2R9M A;  4N4Z A;  2P86 A;  2PNS A;  1KFU L;  1NLJ A;  3MJ5 A;  2GFO A;  4CDD B;  2AVW A;  4OEM A;  9PAP A;  1PBH A;  2YJ8 A;  3CH3 X;  1PXV A;  4YYS A;  4P6E A;  3QJ3 A;  1QXP A;  1AU4 A;  1UKF A;  1NB3 A;  1BGO A;  1PVJ A;  1HUC B;  5F02 A;  3P5V A;  1EF7 A;  3H6S A;  2HXZ A;  4P6G A;  1F2C A;  3V6E A;  1X9Y A;  4OEL A;  4OVZ B;  1Q6K A;  3MOR A;  3I3T A;  1ZCM A;  3KSE A;  1U9X A;  2H7J A;  3U8E A;  1QOL A;  4AXL A;  4AXM A;  3E9S A;  3CBJ A;  2JQG R;  4RNA A;  4PP2 E;  3RVX A;  3O1G A;  3OF9 A;  1F2A A;  2AYO A;  3BY4 A;  1PPD A;  1U9W A;  5CHT A;  2HWK A;  3C0R A;  1K3B B;  4CDC B;  4BOU A;  3CBK A;  2YJC A;  2ATO A;  4BOS A;  1GLO A;  2DZY A;  1TU6 A;  4BQV A;  1CJL A;  1GEC E;  1ME3 A;  4FIP A;  4YYU A;  1KXR A;  4W5B A;  1VSN A;  3GCB A;  3MTN A;  4RF0 A;  2B1M A;  3BB7 A;  3H8C A;  1NQC A;  4D8B A;  1XKG A;  4MSX A;  3BOW A;  4QBB A;  1YK8 A;  1EWP A;  3N3G A;  2R6N A;  2BDZ A;  3IUT A;  5CVN B;  2VHS A;  5KO3 A;  1JQP A;  3BWK A;  2WBF X;  4YYQ A;  4WA6 A;  2G7Y A;  2FRQ A;  3IV2 A;  1AYV A;  1AU0 A;  3BC3 A;  3B79 A;  5CVO B;  2G8J A;  1NL6 A;  4DMX A;  3MP2 A;  4XUI A;  3HHI A;  2AS8 A;  2FUD A;  4RKX A;  3PDF A;  2FO5 A;  4Q8G A;  1DKI A;  2R9C A;  3O0U A;  3IOQ A;  3H89 A;  4OVZ A;  3KKU A;  4KLB A;  2FYE A;  4QRV A;  2FT2 A;  3H8B A;  4BPV A;  1YT7 A;  2FQ9 A;  2J7Q C;  3RNV A;  3S3Q A;  4DMY A;  1CS8 A;  3PRM A;  1ITO A;  1EWO A;  1PPO A;  1AEC A;  2OP3 A;  2AUZ A;  3KWB X;  4PAD A;  1ATK A;  3IEJ A;  3HD3 A;  3K24 A;  1BP4 A;  5CHV A;  4YYV A;  3OIS A;  4ZUX U;  2R9O A;  4HWY A;  4HXD B;  1GMY A;  2JQF R;  5PAD A;  3W30 A;  1AU2 A;  4XR7 A;  4WUR A;  2YJ2 A;  1TLO A;  2E02 A;  3N3K A;  1AIM A;  1SP4 B;  1FH0 A;  1MHW A;  4X6J A;  1DEU A;  5EZQ A;  4YV8 A;  4A5U A;  3OVX A;  3F75 A;  1GCB A;  3QT4 A;  2BTW A;  3P5U A;  4MZO A;  3O65 A;  2NQG A;  2XU4 A;  2FTD A;  1THE A;  3NHE A;  4Q8H A;  2YJB A;  4CDE B;  6PAD A;  2NQI A;  2IBI A;  4YYW A;  4M0W A;  3ZNH A;  5EF4 A;  2DCD A;  4YVA A;  1YK7 A;  5E6J A;  1SNK A;  2AUX A;  3PBH A;  4X6I A;  4D8I A;  3P5X A;  5J94 A;  2IPP B;  3I06 A;  3IFU A;  2BU3 A;  4CDF B;  1PE6 A;  1QDQ A;  1AU3 A;  3KX1 A;  1O0E A;  2BTW B;  3AI8 A;  4I04 A;  3PHW A;  5A24 A;  4QRX A;  2XU3 A;  3E1Z B;  1YVB A;  1NB5 A;  1KHP A;  2CIO A;  4N79 A;  4W5C A;  3PNR A;  3BBA A;  2XU5 A;  3LFY A;  3LXS A;  2E03 A;  2AIM A;  1MEM A;  3OVZ A;  4K7C A;  4R3D A;  3WXF A;  1AYU A;  5EGW A;  5EZS A;  1CVZ A;  1PAD A;  2PAD A;  5JA7 A;  3ZUA A;  4BOZ A;  1CSB B;  2OZ2 A;  2FE8 A;  4N8W A;  3N4C A;  3KWZ A;  3PRP A;  3IHP A;  1PPN A;  5JH3 A;  2O6X A;  2R9F A;  1VJV A;  1STF E;  1CPJ A;  5FPW A;  1KHQ A;  4ZTB A;  3ERV A;  1ME4 A;  2AYN A;  3CH2 X;  3QSD A;  2DJG B;  2NQD B;  4FJC A;  2CB5 A;  4QRG A;  2DOS A;  1F29 A;  1TL9 A;  2DJF B;  3K9M A;  2HHN A;  4BS5 A;  1A6R A;  5CVM A;  2DCA A;  2R9N A;  4REZ A;  3IMA A;  4BOQ A;  2UZJ A;  3KW9 A;  1U9Q X;  1Y08 A;  4PT5 A;  1NPZ A;  2AU1 A;  4I05 A;  2Y6E A;  3F5V A;  2J7Q A;  1POP A;  4X6H A;  4MI7 A;  3W31 A;  1BQI A;  1EWM A;  1CTE A;  2DC8 A;  3K8U A;  3S3R A;  3TMP A;  3PSE A;  2Y5B A;  3D6S A;  4G54 A;  7PCK A; 
#chains in the Genus database with same CATH homology
 3HHA A;  2ARY A;  2VFC A;  2VHF A;  4BSQ A;  4YYR A;  1U9V A;  3USV A;  3TNX A;  1AYW A;  2ACT A;  4BGF A;  2E01 A;  1CQD A;  8PCH A;  1ICF A;  2F7D A;  1U5I A;  4MZS A;  4RY2 A;  4BS6 A;  2P7U A;  4W4U A;  3WXG A;  1YAL A;  2BDL A;  2DC7 A;  4B55 A;  2G8E A;  1KFX L;  3C9E A;  3DF0 A;  2FRA A;  4I07 A;  1CV8 A;  3MHH A;  1Y4H A;  3PW3 A;  3RVV A;  2GHU A;  1BY8 A;  2DC6 A;  4GUZ A;  1M6D A;  4FK5 A;  1PCI A;  2HH5 A;  2E00 A;  3BPM A;  1MEG A;  3P5W A;  1S4V A;  2HD5 A;  2PBH A;  3V6C A;  1MS6 A;  4C5P A;  1QMY A;  2DCC A;  1F2B A;  3HWN A;  1PPP A;  1MIR A;  1ZIV A;  2P0R A;  4QH6 A;  3RVW A;  4PI3 A;  1PIP A;  2DZZ A;  2OUL A;  1W6F A;  2NQA A;  3KFQ A;  2C0Y A;  3OF8 A;  3M99 A;  2DCB A;  2G6D A;  3H7D A;  3WXE A;  4CZW A;  5K16 A;  1CB5 A;  1EWL A;  2B1N A;  1DF0 A;  3BCN A;  2YJ9 A;  2PRE A;  2F1G A;  2DC9 A;  1MDW A;  3BPF A;  2XU1 A;  4PP1 A;  1IWD A;  3MHS A;  2R9M A;  1W4T A;  4N4Z A;  2P86 A;  2PNS A;  1KFU L;  1NLJ A;  4CDD B;  2GFO A;  2AVW A;  4OEM A;  9PAP A;  1PBH A;  2YJ8 A;  3CH3 X;  1PXV A;  4YYS A;  4P6E A;  3QJ3 A;  1QXP A;  1AU4 A;  1NB3 A;  1BGO A;  1HUC B;  5F02 A;  3P5V A;  1EF7 A;  3H6S A;  2HXZ A;  4P6G A;  3LTW A;  1F2C A;  3V6E A;  1X9Y A;  4OEL A;  1Q6K A;  3MOR A;  3I3T A;  1ZCM A;  3KSE A;  1U9X A;  2H7J A;  3U8E A;  1QOL A;  4AXL A;  4AXM A;  3CBJ A;  2JQG R;  4PP2 E;  3RVX A;  3O1G A;  3OF9 A;  1F2A A;  2AYO A;  1PPD A;  1U9W A;  5CHT A;  1K3B B;  4CDC B;  3CBK A;  2YJC A;  2ATO A;  1GLO A;  2DZY A;  1TU6 A;  4BQV A;  1CJL A;  1GEC E;  4NV8 A;  1ME3 A;  1E2T A;  2VFB A;  4FIP A;  4YYU A;  1KXR A;  4W5B A;  1VSN A;  3GCB A;  3MTN A;  2B1M A;  3H8C A;  1NQC A;  1XKG A;  4MSX A;  3BOW A;  4QBB A;  1YK8 A;  1EWP A;  3D9W A;  3N3G A;  2R6N A;  2BDZ A;  3IUT A;  5CVN B;  4NV7 A;  2VHS A;  1JQP A;  1W5R A;  3BWK A;  2WBF X;  4YYQ A;  4WA6 A;  2G7Y A;  2FRQ A;  3IV2 A;  1AYV A;  1AU0 A;  3BC3 A;  3B79 A;  5CVO B;  2G8J A;  1NL6 A;  4DMX A;  4XUI A;  3HHI A;  2AS8 A;  2FUD A;  3PDF A;  2FO5 A;  4Q8G A;  2R9C A;  3O0U A;  3IOQ A;  3H89 A;  3KKU A;  4KLB A;  2FYE A;  4QRV A;  2FT2 A;  3H8B A;  4BPV A;  1YT7 A;  1GX3 A;  2FQ9 A;  3S3Q A;  4DMY A;  1CS8 A;  1ITO A;  1EWO A;  1PPO A;  1AEC A;  2OP3 A;  2AUZ A;  3KWB X;  4PAD A;  1ATK A;  3IEJ A;  3HD3 A;  3K24 A;  1BP4 A;  5CHV A;  4YYV A;  3OIS A;  4ZUX U;  4HWY A;  2R9O A;  1GMY A;  2JQF R;  5PAD A;  1AU2 A;  4XR7 A;  2YJ2 A;  1TLO A;  2E02 A;  3N3K A;  1AIM A;  1SP4 B;  1FH0 A;  1MHW A;  4X6J A;  1DEU A;  4YV8 A;  3OVX A;  3F75 A;  1GCB A;  3QT4 A;  3P5U A;  4MZO A;  2NQG A;  2XU4 A;  2FTD A;  1THE A;  3NHE A;  4Q8H A;  2YJB A;  4CDE B;  6PAD A;  2NQI A;  2IBI A;  4YYW A;  5EF4 A;  2DCD A;  4YVA A;  1YK7 A;  1SNK A;  2AUX A;  3PBH A;  4X6I A;  3P5X A;  5J94 A;  2IPP B;  3I06 A;  4CDF B;  1PE6 A;  1QDQ A;  1AU3 A;  3KX1 A;  1O0E A;  3AI8 A;  4I04 A;  5A24 A;  4QRX A;  2XU3 A;  3E1Z B;  1YVB A;  1NB5 A;  1KHP A;  2CIO A;  4N79 A;  4W5C A;  3PNR A;  3LFY A;  2XU5 A;  3LXS A;  2E03 A;  2AIM A;  1MEM A;  3OVZ A;  4K7C A;  3WXF A;  1AYU A;  5EGW A;  1CVZ A;  1PAD A;  2PAD A;  5JA7 A;  3ZUA A;  1CSB B;  2OZ2 A;  4N8W A;  3N4C A;  3KWZ A;  3IHP A;  1PPN A;  5JH3 A;  2O6X A;  2R9F A;  1VJV A;  1STF E;  2BSZ A;  1CPJ A;  5FPW A;  1KHQ A;  3ERV A;  1ME4 A;  2AYN A;  3CH2 X;  3QSD A;  2DJG B;  2NQD B;  4FJC A;  2CB5 A;  4QRG A;  1F29 A;  1TL9 A;  2DJF B;  3K9M A;  2HHN A;  4BS5 A;  1A6R A;  5CVM A;  2DCA A;  2R9N A;  3IMA A;  3KW9 A;  1U9Q X;  1Y08 A;  1NPZ A;  2AU1 A;  4I05 A;  2Y6E A;  3F5V A;  1POP A;  4X6H A;  1BQI A;  1EWM A;  1CTE A;  2DC8 A;  3K8U A;  3S3R A;  2Y5B A;  3D6S A;  4G54 A;  7PCK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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