5K16A

Crystal structure of free ubiquitin-specific protease 12
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
350
structure length
324
Chain Sequence
SALEKEIGPEQFPVNEHYFGLVNFGNTCYCNSVLQALYFCRPFREKVLAYKSQKKESLLTCLADLFHSIATQKKKVGVIPPKKFITRLRKENELFDNYMQQDAHEFLNYLLNTIADILQEERKQEKQNPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDVEQNTSITHCLRGFSNTETKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRLFNTSGDATNPDRMYDLVAVVVHCGSGPNRGHYIAIVKSHDFWLLFDDDIVEKIDAQAIEEFYGLTSKNSESGYILFYQSRD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Allosteric Activation of Ubiquitin-Specific Proteases by beta-Propeller Proteins UAF1 and WDR20.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Ubiquitin carboxyl-terminal hydrolase 12
total genus 93
structure length 324
sequence length 350
chains with identical sequence B
ec nomenclature ec 3.4.19.12: Ubiquitinyl hydrolase 1.
pdb deposition date 2016-05-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00443 UCH Ubiquitin carboxyl-terminal hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 5k16A00
2YJ8A 5FPWA 4Q8HA 3C9EA 3HD3A 3H89A 5JA7A 1YK7A 2O6XA 2ATOA 1ITOA 2R9FA 3DF0A 1KHQA 2OZ2A 4PP2E 4CDDB 4N79A 4FIPA 2R9OA 1GMYA 3RVVA 4KLBA 1U9QX 2GFOA 1MDWA 2C0YA 4BS5A 3P5VA 2XU4A 1YT7A 4XUIA 2NQGA 5EF4A 1TU6A 4MSXA 2AU1A 4CZWA 2YJ9A 1CSBB 1NLJA 3MTNA 1U9WA 2G8JA 1PPPA 3BPFA 2FO5A 3KFQA 4QRXA 3BOWA 1NL6A 1VJVA 4BQVA 3H8CA 2VHFA 2FTDA 4I04A 2DZYA 2PREA 4WA6A 1CS8A 3IUTA 1NB5A 3N3KA 1MEMA 2AYNA 4YVAA 1S4VA 3IOQA 2P86A 2HXZA 1Y08A 1AU0A 2CB5A 3HWNA 1EWOA 4FK5A 4Q8GA 1PADA 4N4ZA 5A24A 4W5CA 2B1NA 2DC6A 3BPMA 4YYWA 4P6EA 4YYSA 3I06A 2IBIA 3B79A 2FRQA 3H8BA 2OULA 3TNXA 4OEMA 2P7UA 2DC7A 3P5XA 2FUDA 1PPOA 2CIOA 4PP1A 1AYWA 3F5VA 2DCAA 1TL9A 4PADA 2E01A 2F1GA 1CVZA 2XU3A 3USVA 1ME4A 3CBKA 1JQPA 1ME3A 3KW9A 4N8WA 2BDZA 3IHPA 1THEA 1AYVA 5CVNB 3BCNA 1BQIA 2GHUA 4PI3A 4AXMA 4P6GA 3ZUAA 3O0UA 2PADA 1QOLA 4QRVA 3E1ZB 4ZUXU 1CV8A 1MIRA 3P5WA 2DCDA 2AUZA 2G7YA 1TLOA 1ZIVA 1ICFA 1CTEA 4BS6A 1F2BA 1U5IA 2NQDB 1EWPA 4DMYA 2E02A 1GECE 2YJBA 3RVXA 4DMXA 4MZOA 3PNRA 2PNSA 4HWYA 3CH2X 4BPVA 2HHNA 2YJ2A 1CJLA 3O1GA 2ARYA 1YK8A 1Y4HA 2R9CA 2XU1A 2OP3A 3KKUA 3QJ3A 3LXSA 2F7DA 3PW3A 3V6EA 8PCHA 1POPA 3NHEA 5EGWA 3F75A 4CDEB 3CH3X 5CHTA 2DC9A 2BDLA 4I05A 1PCIA 3QSDA 4K7CA 1QMYA 4I07A 2AUXA 3CBJA 1YALA 1SNKA 3IV2A 2PBHA 6PADA 2R9NA 1HUCB 3MHHA 4G54A 3K9MA 3S3RA 2WBFX 4YYUA 4RY2A 5JH3A 3OF9A 1FH0A 3N4CA 1EWMA 4W4UA 3QT4A 3HHAA 1QDQA 3P5UA 2IPPB 3K24A 3RVWA 1AU2A 4CDCB 3U8EA 3N3GA 5J94A 7PCKA 1EWLA 3S3QA 2JQGR 1AIMA 4MZSA 2XU5A 3IMAA 3WXEA 2DJGB 3KWZA 2FT2A 4CDFB 4QRGA 1U9VA 1CQDA 4X6IA 1BP4A 1KFUL 2AVWA 1KXRA 3PBHA 2DJFB 1PXVA 3K8UA 3M99A 1IWDA 3WXFA 1AECA 1F2AA 1NB3A 2YJCA 2DZZA 3KWBX 3OVZA 4YYQA 1MS6A 4YYRA 2HH5A 1BY8A 4W5BA 1MHWA 2Y5BA 4OELA 1O0EA 3GCBA 1F29A 2FQ9A 3V6CA 1BGOA 3KSEA 1CB5A 3OF8A 2VHSA 3IEJA 1DF0A 2E03A 1AU3A 3BWKA 1Q6KA 5F02A 2NQIA 2AIMA 1U9XA 1CPJA 2HD5A 1NPZA 3D6SA 5CHVA 5CVMA 3H6SA 2FYEA 4QBBA 1QXPA 4YYVA 2JQFR 2B1MA 1NQCA 1SP4B 3I3TA 1YVBA 1K3BB 3HHIA 4XR7A 4BSQA 2DC8A 1PPDA 2AS8A 1X9YA 3BC3A 4AXLA 3LFYA 1ZCMA 4X6JA 1GCBA 2P0RA 2H7JA 1PBHA 2FRAA 4YV8A 1ATKA 2G6DA 1MEGA 1DEUA 3H7DA 1A6RA 2R6NA 1VSNA 1AU4A 2DCCA 4QH6A 2NQAA 3MHSA 2Y6EA 2AYOA 1PPNA 2E00A 1STFE 1XKGA 2G8EA 5PADA 3PDFA 5K16A 5CVOB 1M6DA 1KFXL 3KX1A 3OISA 1F2CA 2R9MA 1EF7A 1KHPA 3AI8A 1PIPA 2DCBA 4FJCA 3OVXA 9PAPA 3WXGA 3ERVA 3MORA 1GLOA 1AYUA 4X6HA 2ACTA 1PE6A
chains in the Genus database with same CATH superfamily
2YJ8A 5FPWA 2BTWB 4Q8HA 3C9EA 3HD3A 3H89A 5JA7A 1YK7A 2BTWA 2O6XA 2ATOA 1ITOA 2R9FA 3DF0A 3W30A 1KHQA 2OZ2A 4PP2E 4CDDB 4N79A 4FIPA 2R9OA 1GMYA 3RVVA 4KLBA 1U9QX 2GFOA 1MDWA 2C0YA 4RF1A 4BS5A 3P5VA 2XU4A 1YT7A 4XUIA 2BU3A 2NQGA 5EF4A 1TU6A 4MSXA 2AU1A 4CZWA 2YJ9A 1CSBB 3TRKA 1NLJA 3MTNA 1U9WA 2G8JA 1PPPA 3BPFA 2FO5A 3KFQA 4BOQA 5JZEA 4QRXA 3BOWA 1NL6A 1VJVA 4BQVA 3H8CA 2VHFA 5E6JA 2FTDA 4I04A 2DZYA 2PREA 4WA6A 1CS8A 3IUTA 3PSEA 1NB5A 3N3KA 1MEMA 2AYNA 4YVAA 2Z84A 1S4VA 3IOQA 2P86A 4RKXA 2HXZA 3BY4A 1Y08A 1AU0A 2CB5A 3HWNA 1EWOA 4FK5A 4Q8GA 1PADA 4N4ZA 5A24A 4W5CA 2B1NA 2DC6A 3MP2A 3BPMA 5KO3A 4YYWA 4P6EA 4YYSA 3I06A 2IBIA 3B79A 2FRQA 3H8BA 2OULA 3TNXA 4OEMA 2P7UA 3O65A 2HWKA 2DC7A 2DOSA 3P5XA 2FUDA 1PPOA 2CIOA 4PP1A 3IFUA 1AYWA 3F5VA 2DCAA 1TL9A 4PADA 2E01A 2UZJA 2F1GA 1CVZA 2XU3A 3USVA 1ME4A 3CBKA 1JQPA 1ME3A 3KW9A 4N8WA 2BDZA 3IHPA 1THEA 1AYVA 5CVNB 3BCNA 4OVZA 1BQIA 2GHUA 4IUMA 4PI3A 4AXMA 4HXDB 4P6GA 3ZUAA 3O0UA 2PADA 1QOLA 4QRVA 3E1ZB 4ZUXU 1CV8A 1MIRA 3P5WA 1DKIA 2J7QA 2DCDA 2AUZA 2G7YA 1TLOA 1ZIVA 4GUAA 1ICFA 1CTEA 4BS6A 1F2BA 1U5IA 2NQDB 1EWPA 4DMYA 2E02A 1GECE 2YJBA 3RVXA 4DMXA 4MZOA 3PNRA 2PNSA 4HWYA 3CH2X 4BPVA 2HHNA 2YJ2A 1CJLA 3O1GA 2ARYA 1YK8A 1Y4HA 2R9CA 2XU1A 3E9SA 2OP3A 3KKUA 3QJ3A 3LXSA 2F7DA 3PW3A 3V6EA 5EZQA 8PCHA 1POPA 1UKFA 4A5UA 2JRIA 3NHEA 5EGWA 3F75A 2JTCA 3MTVA 4CDEB 3CH3X 5CHTA 2DC9A 2BDLA 4I05A 1PCIA 3QSDA 4K7CA 1QMYA 4I07A 2AUXA 3CBJA 1YALA 1SNKA 3IV2A 2PBHA 4RNAA 6PADA 2R9NA 1HUCB 4MI7A 3MHHA 4G54A 3K9MA 3S3RA 3B21A 2WBFX 4YYUA 4IP3A 4RY2A 3PT2A 5JH3A 3OF9A 1FH0A 4BOUA 3N4CA 1EWMA 3MJ5A 4R3DA 4W4UA 3QT4A 3HHAA 1QDQA 3P5UA 2IPPB 3K24A 3RVWA 4ZTBA 4BOPA 1AU2A 4CDCB 3U8EA 3N3GA 5J94A 4PT5A 7PCKA 1EWLA 3S3QA 2JQGR 1AIMA 4MZSA 5EZSA 2XU5A 3IMAA 3PRMA 3W31A 3WXEA 2DJGB 3KWZA 2FT2A 4CDFB 3TMPA 4QRGA 1U9VA 1CQDA 2J7QC 4X6IA 1BP4A 1KFUL 2AVWA 1KXRA 3PBHA 2DJFB 1PXVA 3K8UA 3M99A 1IWDA 4OW0A 3WXFA 1AECA 1F2AA 1NB3A 2YJCA 2DZZA 3KWBX 3OVZA 4YYQA 1MS6A 4XZXA 4YYRA 2HH5A 1BY8A 4W5BA 1YZBA 1MHWA 2Y5BA 4OELA 1O0EA 3GCBA 1F29A 2FQ9A 3V6CA 4M0WA 1BGOA 3KSEA 1CB5A 3OF8A 3OQCA 2VHSA 3IEJA 1DF0A 2E03A 1AU3A 3BWKA 4D8EA 1Q6KA 5F02A 2NQIA 2AGAA 2AIMA 1U9XA 1CPJA 2HD5A 1NPZA 3D6SA 3PHXA 5CHVA 5CVMA 3H6SA 2FYEA 4QBBA 1QXPA 4YYVA 2FE8A 2JQFR 2B1MA 1NQCA 1SP4B 3RNVA 4D8IA 3I3TA 1YVBA 1K3BB 1PVJA 3HHIA 4XR7A 4BSQA 2DC8A 1PPDA 2AS8A 3PHWA 1X9YA 3BC3A 4AXLA 3C0RA 3LFYA 1ZCMA 4REZA 4X6JA 1GCBA 2P0RA 2H7JA 1PBHA 4P16A 2FRAA 4YV8A 1ATKA 2G6DA 1MEGA 3PHUA 1DEUA 3H7DA 1A6RA 2R6NA 3BBAA 1VSNA 3BB7A 1AU4A 2DCCA 4QH6A 4D8BA 2NQAA 3MHSA 4WURA 2Y6EA 2AYOA 1PPNA 2E00A 1STFE 1XKGA 2G8EA 4BOSA 5PADA 4MM3B 3PDFA 5K16A 5CVOB 1M6DA 1KFXL 3KX1A 3OISA 4BOZA 1F2CA 2R9MA 1EF7A 1KHPA 3AI8A 1PIPA 2DCBA 4RF0A 3PRPA 4FJCA 3OVXA 3ZNHA 9PAPA 3WXGA 4OVZB 3ERVA 3MORA 1GLOA 1AYUA 4X6HA 2ACTA 1PE6A
chains in the Genus database with same CATH topology
2YJ8A 5FPWA 4Q8HA 1W5RA 3C9EA 3HD3A 3H89A 5JA7A 1YK7A 2O6XA 2ATOA 1ITOA 2R9FA 3DF0A 1KHQA 2OZ2A 4PP2E 4CDDB 4N79A 4FIPA 2R9OA 1GMYA 3RVVA 4KLBA 1U9QX 2GFOA 1MDWA 2C0YA 2VFCA 4BS5A 3P5VA 2XU4A 1YT7A 4XUIA 2NQGA 5EF4A 1TU6A 4MSXA 2AU1A 4CZWA 2YJ9A 1CSBB 1NLJA 3MTNA 1U9WA 3LTWA 2G8JA 1PPPA 3BPFA 2FO5A 3KFQA 4QRXA 3BOWA 1NL6A 1VJVA 4BQVA 3H8CA 2VHFA 2FTDA 4I04A 2DZYA 2PREA 4WA6A 1CS8A 3IUTA 1NB5A 3N3KA 1MEMA 2AYNA 4YVAA 1S4VA 3IOQA 2P86A 2HXZA 2BSZA 1Y08A 1AU0A 2CB5A 3HWNA 1EWOA 4FK5A 4Q8GA 3D9WA 1PADA 4N4ZA 5A24A 4W5CA 2B1NA 2DC6A 3BPMA 4YYWA 4P6EA 4YYSA 3I06A 2IBIA 3B79A 2FRQA 3H8BA 2OULA 3TNXA 4OEMA 2P7UA 2DC7A 3P5XA 2FUDA 1PPOA 2CIOA 4PP1A 4BGFA 1AYWA 3F5VA 2DCAA 1TL9A 4PADA 2E01A 2F1GA 1CVZA 2XU3A 3USVA 1ME4A 3CBKA 1JQPA 1ME3A 3KW9A 4N8WA 2BDZA 3IHPA 1THEA 1AYVA 5CVNB 3BCNA 1BQIA 2GHUA 4PI3A 4AXMA 4B55A 4P6GA 3ZUAA 3O0UA 2PADA 1QOLA 4QRVA 3E1ZB 4ZUXU 1CV8A 1MIRA 3P5WA 2DCDA 2AUZA 2G7YA 1TLOA 1ZIVA 1ICFA 1CTEA 4BS6A 1F2BA 1U5IA 2NQDB 4C5PA 1EWPA 4DMYA 2E02A 1GECE 2YJBA 3RVXA 4DMXA 4MZOA 3PNRA 2PNSA 4HWYA 3CH2X 4BPVA 2HHNA 2YJ2A 1CJLA 3O1GA 2ARYA 1YK8A 1Y4HA 2R9CA 2XU1A 2OP3A 3KKUA 1W6FA 3QJ3A 3LXSA 2F7DA 3PW3A 3V6EA 8PCHA 4GUZA 1POPA 3NHEA 5EGWA 3F75A 4CDEB 3CH3X 5CHTA 2DC9A 2BDLA 4I05A 1PCIA 3QSDA 4K7CA 1QMYA 4I07A 2AUXA 3CBJA 1YALA 1SNKA 3IV2A 2PBHA 6PADA 2R9NA 1HUCB 3MHHA 4G54A 3K9MA 3S3RA 2WBFX 4YYUA 4RY2A 5JH3A 3OF9A 1FH0A 3N4CA 1EWMA 4W4UA 3QT4A 3HHAA 1QDQA 3P5UA 2IPPB 3K24A 3RVWA 1AU2A 4CDCB 3U8EA 3N3GA 5J94A 7PCKA 1EWLA 3S3QA 2JQGR 1AIMA 4MZSA 2XU5A 3IMAA 3WXEA 2DJGB 3KWZA 2FT2A 4CDFB 4QRGA 1U9VA 1CQDA 4X6IA 1BP4A 1KFUL 2AVWA 1KXRA 3PBHA 2DJFB 1PXVA 3K8UA 3M99A 1IWDA 3WXFA 1AECA 1F2AA 1NB3A 2YJCA 2DZZA 3KWBX 3OVZA 4YYQA 1MS6A 1GX3A 4YYRA 2HH5A 1BY8A 4W5BA 1MHWA 2Y5BA 4OELA 1O0EA 3GCBA 1F29A 2FQ9A 4NV7A 3V6CA 1BGOA 3KSEA 1CB5A 3OF8A 2VHSA 3IEJA 1DF0A 2E03A 1AU3A 3BWKA 1Q6KA 5F02A 2NQIA 2AIMA 1U9XA 1CPJA 2VFBA 2HD5A 1NPZA 3D6SA 5CHVA 5CVMA 3H6SA 2FYEA 4QBBA 1QXPA 4YYVA 2JQFR 2B1MA 1NQCA 1SP4B 3I3TA 1YVBA 1K3BB 3HHIA 4XR7A 4BSQA 2DC8A 1PPDA 2AS8A 1X9YA 3BC3A 4AXLA 3LFYA 1ZCMA 4X6JA 1GCBA 2P0RA 2H7JA 1W4TA 1PBHA 2FRAA 4YV8A 1ATKA 2G6DA 1MEGA 1DEUA 3H7DA 1A6RA 2R6NA 1VSNA 1AU4A 2DCCA 4QH6A 2NQAA 3MHSA 2Y6EA 2AYOA 1PPNA 2E00A 1STFE 1XKGA 2G8EA 5PADA 3PDFA 5K16A 5CVOB 1M6DA 1KFXL 3KX1A 4NV8A 3OISA 1F2CA 2R9MA 1EF7A 1KHPA 3AI8A 1PIPA 2DCBA 4FJCA 3OVXA 9PAPA 3WXGA 3ERVA 3MORA 1GLOA 1AYUA 4X6HA 2ACTA 1PE6A 1E2TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YJ8 A;  5FPW A;  4Q8H A;  3C9E A;  3HD3 A;  3H89 A;  5JA7 A;  1YK7 A;  2O6X A;  2ATO A;  1ITO A;  2R9F A;  3DF0 A;  1KHQ A;  2OZ2 A;  4PP2 E;  4CDD B;  4N79 A;  4FIP A;  2R9O A;  1GMY A;  3RVV A;  4KLB A;  1U9Q X;  2GFO A;  1MDW A;  2C0Y A;  4BS5 A;  3P5V A;  2XU4 A;  1YT7 A;  4XUI A;  2NQG A;  5EF4 A;  1TU6 A;  4MSX A;  2AU1 A;  4CZW A;  2YJ9 A;  1CSB B;  1NLJ A;  3MTN A;  1U9W A;  2G8J A;  1PPP A;  3BPF A;  2FO5 A;  3KFQ A;  4QRX A;  3BOW A;  1NL6 A;  1VJV A;  4BQV A;  3H8C A;  2VHF A;  2FTD A;  4I04 A;  2DZY A;  2PRE A;  4WA6 A;  1CS8 A;  3IUT A;  1NB5 A;  3N3K A;  1MEM A;  2AYN A;  4YVA A;  1S4V A;  3IOQ A;  2P86 A;  2HXZ A;  1Y08 A;  1AU0 A;  2CB5 A;  3HWN A;  1EWO A;  4FK5 A;  4Q8G A;  1PAD A;  4N4Z A;  5A24 A;  4W5C A;  2B1N A;  2DC6 A;  3BPM A;  4YYW A;  4P6E A;  4YYS A;  3I06 A;  2IBI A;  3B79 A;  2FRQ A;  3H8B A;  2OUL A;  3TNX A;  4OEM A;  2P7U A;  2DC7 A;  3P5X A;  2FUD A;  1PPO A;  2CIO A;  4PP1 A;  1AYW A;  3F5V A;  2DCA A;  1TL9 A;  4PAD A;  2E01 A;  2F1G A;  1CVZ A;  2XU3 A;  3USV A;  1ME4 A;  3CBK A;  1JQP A;  1ME3 A;  3KW9 A;  4N8W A;  2BDZ A;  3IHP A;  1THE A;  1AYV A;  5CVN B;  3BCN A;  1BQI A;  2GHU A;  4PI3 A;  4AXM A;  4P6G A;  3ZUA A;  3O0U A;  2PAD A;  1QOL A;  4QRV A;  3E1Z B;  4ZUX U;  1CV8 A;  1MIR A;  3P5W A;  2DCD A;  2AUZ A;  2G7Y A;  1TLO A;  1ZIV A;  1ICF A;  1CTE A;  4BS6 A;  1F2B A;  1U5I A;  2NQD B;  1EWP A;  4DMY A;  2E02 A;  1GEC E;  2YJB A;  3RVX A;  4DMX A;  4MZO A;  3PNR A;  2PNS A;  4HWY A;  3CH2 X;  4BPV A;  2HHN A;  2YJ2 A;  1CJL A;  3O1G A;  2ARY A;  1YK8 A;  1Y4H A;  2R9C A;  2XU1 A;  2OP3 A;  3KKU A;  3QJ3 A;  3LXS A;  2F7D A;  3PW3 A;  3V6E A;  8PCH A;  1POP A;  3NHE A;  5EGW A;  3F75 A;  4CDE B;  3CH3 X;  5CHT A;  2DC9 A;  2BDL A;  4I05 A;  1PCI A;  3QSD A;  4K7C A;  1QMY A;  4I07 A;  2AUX A;  3CBJ A;  1YAL A;  1SNK A;  3IV2 A;  2PBH A;  6PAD A;  2R9N A;  1HUC B;  3MHH A;  4G54 A;  3K9M A;  3S3R A;  2WBF X;  4YYU A;  4RY2 A;  5JH3 A;  3OF9 A;  1FH0 A;  3N4C A;  1EWM A;  4W4U A;  3QT4 A;  3HHA A;  1QDQ A;  3P5U A;  2IPP B;  3K24 A;  3RVW A;  1AU2 A;  4CDC B;  3U8E A;  3N3G A;  5J94 A;  7PCK A;  1EWL A;  3S3Q A;  2JQG R;  1AIM A;  4MZS A;  2XU5 A;  3IMA A;  3WXE A;  2DJG B;  3KWZ A;  2FT2 A;  4CDF B;  4QRG A;  1U9V A;  1CQD A;  4X6I A;  1BP4 A;  1KFU L;  2AVW A;  1KXR A;  3PBH A;  2DJF B;  1PXV A;  3K8U A;  3M99 A;  1IWD A;  3WXF A;  1AEC A;  1F2A A;  1NB3 A;  2YJC A;  2DZZ A;  3KWB X;  3OVZ A;  4YYQ A;  1MS6 A;  4YYR A;  2HH5 A;  1BY8 A;  4W5B A;  1MHW A;  2Y5B A;  4OEL A;  1O0E A;  3GCB A;  1F29 A;  2FQ9 A;  3V6C A;  1BGO A;  3KSE A;  1CB5 A;  3OF8 A;  2VHS A;  3IEJ A;  1DF0 A;  2E03 A;  1AU3 A;  3BWK A;  1Q6K A;  5F02 A;  2NQI A;  2AIM A;  1U9X A;  1CPJ A;  2HD5 A;  1NPZ A;  3D6S A;  5CHV A;  5CVM A;  3H6S A;  2FYE A;  4QBB A;  1QXP A;  4YYV A;  2JQF R;  2B1M A;  1NQC A;  1SP4 B;  3I3T A;  1YVB A;  1K3B B;  3HHI A;  4XR7 A;  4BSQ A;  2DC8 A;  1PPD A;  2AS8 A;  1X9Y A;  3BC3 A;  4AXL A;  3LFY A;  1ZCM A;  4X6J A;  1GCB A;  2P0R A;  2H7J A;  1PBH A;  2FRA A;  4YV8 A;  1ATK A;  2G6D A;  1MEG A;  1DEU A;  3H7D A;  1A6R A;  2R6N A;  1VSN A;  1AU4 A;  2DCC A;  4QH6 A;  2NQA A;  3MHS A;  2Y6E A;  2AYO A;  1PPN A;  2E00 A;  1STF E;  1XKG A;  2G8E A;  5PAD A;  3PDF A;  5K16 A;  5CVO B;  1M6D A;  1KFX L;  3KX1 A;  3OIS A;  1F2C A;  2R9M A;  1EF7 A;  1KHP A;  3AI8 A;  1PIP A;  2DCB A;  4FJC A;  3OVX A;  9PAP A;  3WXG A;  3ERV A;  3MOR A;  1GLO A;  1AYU A;  4X6H A;  2ACT A;  1PE6 A; 
#chains in the Genus database with same CATH topology
 2YJ8 A;  5FPW A;  2BTW B;  4Q8H A;  3C9E A;  3HD3 A;  3H89 A;  5JA7 A;  1YK7 A;  2BTW A;  2O6X A;  2ATO A;  1ITO A;  2R9F A;  3DF0 A;  3W30 A;  1KHQ A;  2OZ2 A;  4PP2 E;  4CDD B;  4N79 A;  4FIP A;  2R9O A;  1GMY A;  3RVV A;  4KLB A;  1U9Q X;  2GFO A;  1MDW A;  2C0Y A;  4RF1 A;  4BS5 A;  3P5V A;  2XU4 A;  1YT7 A;  4XUI A;  2BU3 A;  2NQG A;  5EF4 A;  1TU6 A;  4MSX A;  2AU1 A;  4CZW A;  2YJ9 A;  1CSB B;  3TRK A;  1NLJ A;  3MTN A;  1U9W A;  2G8J A;  1PPP A;  3BPF A;  2FO5 A;  3KFQ A;  4BOQ A;  5JZE A;  4QRX A;  3BOW A;  1NL6 A;  1VJV A;  4BQV A;  3H8C A;  2VHF A;  5E6J A;  2FTD A;  4I04 A;  2DZY A;  2PRE A;  4WA6 A;  1CS8 A;  3IUT A;  3PSE A;  1NB5 A;  3N3K A;  1MEM A;  2AYN A;  4YVA A;  2Z84 A;  1S4V A;  3IOQ A;  2P86 A;  4RKX A;  2HXZ A;  3BY4 A;  1Y08 A;  1AU0 A;  2CB5 A;  3HWN A;  1EWO A;  4FK5 A;  4Q8G A;  1PAD A;  4N4Z A;  5A24 A;  4W5C A;  2B1N A;  2DC6 A;  3MP2 A;  3BPM A;  5KO3 A;  4YYW A;  4P6E A;  4YYS A;  3I06 A;  2IBI A;  3B79 A;  2FRQ A;  3H8B A;  2OUL A;  3TNX A;  4OEM A;  2P7U A;  3O65 A;  2HWK A;  2DC7 A;  2DOS A;  3P5X A;  2FUD A;  1PPO A;  2CIO A;  4PP1 A;  3IFU A;  1AYW A;  3F5V A;  2DCA A;  1TL9 A;  4PAD A;  2E01 A;  2UZJ A;  2F1G A;  1CVZ A;  2XU3 A;  3USV A;  1ME4 A;  3CBK A;  1JQP A;  1ME3 A;  3KW9 A;  4N8W A;  2BDZ A;  3IHP A;  1THE A;  1AYV A;  5CVN B;  3BCN A;  4OVZ A;  1BQI A;  2GHU A;  4IUM A;  4PI3 A;  4AXM A;  4HXD B;  4P6G A;  3ZUA A;  3O0U A;  2PAD A;  1QOL A;  4QRV A;  3E1Z B;  4ZUX U;  1CV8 A;  1MIR A;  3P5W A;  1DKI A;  2J7Q A;  2DCD A;  2AUZ A;  2G7Y A;  1TLO A;  1ZIV A;  4GUA A;  1ICF A;  1CTE A;  4BS6 A;  1F2B A;  1U5I A;  2NQD B;  1EWP A;  4DMY A;  2E02 A;  1GEC E;  2YJB A;  3RVX A;  4DMX A;  4MZO A;  3PNR A;  2PNS A;  4HWY A;  3CH2 X;  4BPV A;  2HHN A;  2YJ2 A;  1CJL A;  3O1G A;  2ARY A;  1YK8 A;  1Y4H A;  2R9C A;  2XU1 A;  3E9S A;  2OP3 A;  3KKU A;  3QJ3 A;  3LXS A;  2F7D A;  3PW3 A;  3V6E A;  5EZQ A;  8PCH A;  1POP A;  1UKF A;  4A5U A;  2JRI A;  3NHE A;  5EGW A;  3F75 A;  2JTC A;  3MTV A;  4CDE B;  3CH3 X;  5CHT A;  2DC9 A;  2BDL A;  4I05 A;  1PCI A;  3QSD A;  4K7C A;  1QMY A;  4I07 A;  2AUX A;  3CBJ A;  1YAL A;  1SNK A;  3IV2 A;  2PBH A;  4RNA A;  6PAD A;  2R9N A;  1HUC B;  4MI7 A;  3MHH A;  4G54 A;  3K9M A;  3S3R A;  3B21 A;  2WBF X;  4YYU A;  4IP3 A;  4RY2 A;  3PT2 A;  5JH3 A;  3OF9 A;  1FH0 A;  4BOU A;  3N4C A;  1EWM A;  3MJ5 A;  4R3D A;  4W4U A;  3QT4 A;  3HHA A;  1QDQ A;  3P5U A;  2IPP B;  3K24 A;  3RVW A;  4ZTB A;  4BOP A;  1AU2 A;  4CDC B;  3U8E A;  3N3G A;  5J94 A;  4PT5 A;  7PCK A;  1EWL A;  3S3Q A;  2JQG R;  1AIM A;  4MZS A;  5EZS A;  2XU5 A;  3IMA A;  3PRM A;  3W31 A;  3WXE A;  2DJG B;  3KWZ A;  2FT2 A;  4CDF B;  3TMP A;  4QRG A;  1U9V A;  1CQD A;  2J7Q C;  4X6I A;  1BP4 A;  1KFU L;  2AVW A;  1KXR A;  3PBH A;  2DJF B;  1PXV A;  3K8U A;  3M99 A;  1IWD A;  4OW0 A;  3WXF A;  1AEC A;  1F2A A;  1NB3 A;  2YJC A;  2DZZ A;  3KWB X;  3OVZ A;  4YYQ A;  1MS6 A;  4XZX A;  4YYR A;  2HH5 A;  1BY8 A;  4W5B A;  1YZB A;  1MHW A;  2Y5B A;  4OEL A;  1O0E A;  3GCB A;  1F29 A;  2FQ9 A;  3V6C A;  4M0W A;  1BGO A;  3KSE A;  1CB5 A;  3OF8 A;  3OQC A;  2VHS A;  3IEJ A;  1DF0 A;  2E03 A;  1AU3 A;  3BWK A;  4D8E A;  1Q6K A;  5F02 A;  2NQI A;  2AGA A;  2AIM A;  1U9X A;  1CPJ A;  2HD5 A;  1NPZ A;  3D6S A;  3PHX A;  5CHV A;  5CVM A;  3H6S A;  2FYE A;  4QBB A;  1QXP A;  4YYV A;  2FE8 A;  2JQF R;  2B1M A;  1NQC A;  1SP4 B;  3RNV A;  4D8I A;  3I3T A;  1YVB A;  1K3B B;  1PVJ A;  3HHI A;  4XR7 A;  4BSQ A;  2DC8 A;  1PPD A;  2AS8 A;  3PHW A;  1X9Y A;  3BC3 A;  4AXL A;  3C0R A;  3LFY A;  1ZCM A;  4REZ A;  4X6J A;  1GCB A;  2P0R A;  2H7J A;  1PBH A;  4P16 A;  2FRA A;  4YV8 A;  1ATK A;  2G6D A;  1MEG A;  3PHU A;  1DEU A;  3H7D A;  1A6R A;  2R6N A;  3BBA A;  1VSN A;  3BB7 A;  1AU4 A;  2DCC A;  4QH6 A;  4D8B A;  2NQA A;  3MHS A;  4WUR A;  2Y6E A;  2AYO A;  1PPN A;  2E00 A;  1STF E;  1XKG A;  2G8E A;  4BOS A;  5PAD A;  4MM3 B;  3PDF A;  5K16 A;  5CVO B;  1M6D A;  1KFX L;  3KX1 A;  3OIS A;  4BOZ A;  1F2C A;  2R9M A;  1EF7 A;  1KHP A;  3AI8 A;  1PIP A;  2DCB A;  4RF0 A;  3PRP A;  4FJC A;  3OVX A;  3ZNH A;  9PAP A;  3WXG A;  4OVZ B;  3ERV A;  3MOR A;  1GLO A;  1AYU A;  4X6H A;  2ACT A;  1PE6 A; 
#chains in the Genus database with same CATH homology
 2YJ8 A;  5FPW A;  4Q8H A;  1W5R A;  3C9E A;  3HD3 A;  3H89 A;  5JA7 A;  1YK7 A;  2O6X A;  2ATO A;  1ITO A;  2R9F A;  3DF0 A;  1KHQ A;  2OZ2 A;  4PP2 E;  4CDD B;  4N79 A;  4FIP A;  2R9O A;  1GMY A;  3RVV A;  4KLB A;  1U9Q X;  2GFO A;  1MDW A;  2C0Y A;  2VFC A;  4BS5 A;  3P5V A;  2XU4 A;  1YT7 A;  4XUI A;  2NQG A;  5EF4 A;  1TU6 A;  4MSX A;  2AU1 A;  4CZW A;  2YJ9 A;  1CSB B;  1NLJ A;  3MTN A;  1U9W A;  3LTW A;  2G8J A;  1PPP A;  3BPF A;  2FO5 A;  3KFQ A;  4QRX A;  3BOW A;  1NL6 A;  1VJV A;  4BQV A;  3H8C A;  2VHF A;  2FTD A;  4I04 A;  2DZY A;  2PRE A;  4WA6 A;  1CS8 A;  3IUT A;  1NB5 A;  3N3K A;  1MEM A;  2AYN A;  4YVA A;  1S4V A;  3IOQ A;  2P86 A;  2HXZ A;  2BSZ A;  1Y08 A;  1AU0 A;  2CB5 A;  3HWN A;  1EWO A;  4FK5 A;  4Q8G A;  3D9W A;  1PAD A;  4N4Z A;  5A24 A;  4W5C A;  2B1N A;  2DC6 A;  3BPM A;  4YYW A;  4P6E A;  4YYS A;  3I06 A;  2IBI A;  3B79 A;  2FRQ A;  3H8B A;  2OUL A;  3TNX A;  4OEM A;  2P7U A;  2DC7 A;  3P5X A;  2FUD A;  1PPO A;  2CIO A;  4PP1 A;  4BGF A;  1AYW A;  3F5V A;  2DCA A;  1TL9 A;  4PAD A;  2E01 A;  2F1G A;  1CVZ A;  2XU3 A;  3USV A;  1ME4 A;  3CBK A;  1JQP A;  1ME3 A;  3KW9 A;  4N8W A;  2BDZ A;  3IHP A;  1THE A;  1AYV A;  5CVN B;  3BCN A;  1BQI A;  2GHU A;  4PI3 A;  4AXM A;  4B55 A;  4P6G A;  3ZUA A;  3O0U A;  2PAD A;  1QOL A;  4QRV A;  3E1Z B;  4ZUX U;  1CV8 A;  1MIR A;  3P5W A;  2DCD A;  2AUZ A;  2G7Y A;  1TLO A;  1ZIV A;  1ICF A;  1CTE A;  4BS6 A;  1F2B A;  1U5I A;  2NQD B;  4C5P A;  1EWP A;  4DMY A;  2E02 A;  1GEC E;  2YJB A;  3RVX A;  4DMX A;  4MZO A;  3PNR A;  2PNS A;  4HWY A;  3CH2 X;  4BPV A;  2HHN A;  2YJ2 A;  1CJL A;  3O1G A;  2ARY A;  1YK8 A;  1Y4H A;  2R9C A;  2XU1 A;  2OP3 A;  3KKU A;  1W6F A;  3QJ3 A;  3LXS A;  2F7D A;  3PW3 A;  3V6E A;  8PCH A;  4GUZ A;  1POP A;  3NHE A;  5EGW A;  3F75 A;  4CDE B;  3CH3 X;  5CHT A;  2DC9 A;  2BDL A;  4I05 A;  1PCI A;  3QSD A;  4K7C A;  1QMY A;  4I07 A;  2AUX A;  3CBJ A;  1YAL A;  1SNK A;  3IV2 A;  2PBH A;  6PAD A;  2R9N A;  1HUC B;  3MHH A;  4G54 A;  3K9M A;  3S3R A;  2WBF X;  4YYU A;  4RY2 A;  5JH3 A;  3OF9 A;  1FH0 A;  3N4C A;  1EWM A;  4W4U A;  3QT4 A;  3HHA A;  1QDQ A;  3P5U A;  2IPP B;  3K24 A;  3RVW A;  1AU2 A;  4CDC B;  3U8E A;  3N3G A;  5J94 A;  7PCK A;  1EWL A;  3S3Q A;  2JQG R;  1AIM A;  4MZS A;  2XU5 A;  3IMA A;  3WXE A;  2DJG B;  3KWZ A;  2FT2 A;  4CDF B;  4QRG A;  1U9V A;  1CQD A;  4X6I A;  1BP4 A;  1KFU L;  2AVW A;  1KXR A;  3PBH A;  2DJF B;  1PXV A;  3K8U A;  3M99 A;  1IWD A;  3WXF A;  1AEC A;  1F2A A;  1NB3 A;  2YJC A;  2DZZ A;  3KWB X;  3OVZ A;  4YYQ A;  1MS6 A;  1GX3 A;  4YYR A;  2HH5 A;  1BY8 A;  4W5B A;  1MHW A;  2Y5B A;  4OEL A;  1O0E A;  3GCB A;  1F29 A;  2FQ9 A;  4NV7 A;  3V6C A;  1BGO A;  3KSE A;  1CB5 A;  3OF8 A;  2VHS A;  3IEJ A;  1DF0 A;  2E03 A;  1AU3 A;  3BWK A;  1Q6K A;  5F02 A;  2NQI A;  2AIM A;  1U9X A;  1CPJ A;  2VFB A;  2HD5 A;  1NPZ A;  3D6S A;  5CHV A;  5CVM A;  3H6S A;  2FYE A;  4QBB A;  1QXP A;  4YYV A;  2JQF R;  2B1M A;  1NQC A;  1SP4 B;  3I3T A;  1YVB A;  1K3B B;  3HHI A;  4XR7 A;  4BSQ A;  2DC8 A;  1PPD A;  2AS8 A;  1X9Y A;  3BC3 A;  4AXL A;  3LFY A;  1ZCM A;  4X6J A;  1GCB A;  2P0R A;  2H7J A;  1W4T A;  1PBH A;  2FRA A;  4YV8 A;  1ATK A;  2G6D A;  1MEG A;  1DEU A;  3H7D A;  1A6R A;  2R6N A;  1VSN A;  1AU4 A;  2DCC A;  4QH6 A;  2NQA A;  3MHS A;  2Y6E A;  2AYO A;  1PPN A;  2E00 A;  1STF E;  1XKG A;  2G8E A;  5PAD A;  3PDF A;  5K16 A;  5CVO B;  1M6D A;  1KFX L;  3KX1 A;  4NV8 A;  3OIS A;  1F2C A;  2R9M A;  1EF7 A;  1KHP A;  3AI8 A;  1PIP A;  2DCB A;  4FJC A;  3OVX A;  9PAP A;  3WXG A;  3ERV A;  3MOR A;  1GLO A;  1AYU A;  4X6H A;  2ACT A;  1PE6 A;  1E2T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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