8PCHA

Crystal structure of porcine cathepsin h determined at 2.1 angstrom resolution: location of the mini-chain c-terminal carboxyl group defines cathepsin h aminopeptidase function
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
220
structure length
220
Chain Sequence
YPPSMDWRKKGNFVSPVKNQGSCGSCWTFSTTGALESAVAIATGKMLSLAEQQLVDCAQNFNNHGCQGGLPSQAFEYIRYNKGIMGEDTYPYKGQDDHCKFQPDKAIAFVKDVANITMNDEEAMVEAVALYNPVSFAFEVTNDFLMYRKGIYSSTSCHKTPDKVNHAVLAVGYGEENGIPYWIVKNSWGPQWGMNGYFLIERGKNMCGLAACASYPIPLV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of porcine cathepsin H determined at 2.1 A resolution: location of the mini-chain C-terminal carboxyl group defines cathepsin H aminopeptidase function.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords CATHEPSIN H
total genus 57
structure length 220
sequence length 220
ec nomenclature ec 3.4.22.16: Cathepsin H.
pdb deposition date 1997-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 8pchA00
1NL6A 2FO5A 1EWLA 6PADA 4P6GA 3PDFA 1ICFA 2GHUA 2IPPB 4Q8GA 1K3BB 4OEMA 1QMYA 5JA7A 4KLBA 1S4VA 3BCNA 1CPJA 4PP2E 4BPVA 2AIMA 1PE6A 1QOLA 1MHWA 2DCAA 3H8CA 3IOQA 3N3KA 2DCCA 1EWOA 2E02A 3KFQA 1IWDA 1CQDA 4FJCA 3HD3A 2G7YA 2AU1A 1AU4A 3BOWA 3LXSA 3K8UA 1DF0A 3CBJA 3U8EA 3KKUA 4N4ZA 1Y4HA 1PXVA 5PADA 1U9XA 2XU5A 2E01A 2F1GA 1U5IA 1ATKA 5CHVA 3MTNA 3LFYA 4N79A 2DJFB 5JH3A 2DC6A 3BPFA 1TLOA 3E1ZB 3HHAA 1YK7A 1CTEA 3KX1A 1TL9A 3O1GA 1CSBB 3KW9A 4RY2A 4BS6A 2WBFX 2E00A 4OELA 1U9WA 1SNKA 1EWMA 2FYEA 1SP4B 3MHSA 1MIRA 2BDLA 2FRQA 2G8EA 4CDCB 3NHEA 1AU2A 2YJ8A 4PP1A 4PI3A 8PCHA 1AYVA 1BY8A 2JQGR 4XR7A 1QDQA 4FIPA 4W5BA 3MORA 4P6EA 2R9FA 1STFE 3F75A 1PPDA 9PAPA 3GCBA 3PW3A 1ZCMA 2E03A 1MEMA 3F5VA 4QRVA 2YJ9A 2R9OA 2DC8A 1Q6KA 1AU3A 5CHTA 4BS5A 3AI8A 2R9CA 3K9MA 2XU4A 1NLJA 2GFOA 1MS6A 2YJ2A 3S3RA 4G54A 2G8JA 5FPWA 1ME3A 1BP4A 3WXEA 3QSDA 2DC7A 1M6DA 1CS8A 1KXRA 4QRGA 4W4UA 5EGWA 1CB5A 3OF8A 3V6EA 3K24A 2DZYA 5J94A 1XKGA 3RVVA 2DCDA 2P0RA 2YJCA 5EF4A 1F2BA 3KWZA 1BGOA 2AUXA 4WA6A 2NQGA 4MSXA 3M99A 4W5CA 4MZSA 3H7DA 4BSQA 3HHIA 1CV8A 3TNXA 2AVWA 2F7DA 1GLOA 2R6NA 1NB5A 4YYWA 2Y5BA 4MZOA 2XU3A 2AS8A 1DEUA 1Y08A 3D6SA 1MDWA 4DMXA 1PIPA 4I05A 2CB5A 3CH2X 3H6SA 2HHNA 2R9MA 2CIOA 3QT4A 2HXZA 1PCIA 3I3TA 5K16A 1AIMA 1VJVA 2NQDB 4YYUA 4CDFB 3RVXA 4YYRA 1PBHA 2BDZA 1KHPA 3IHPA 1F2CA 4DMYA 2VHFA 4N8WA 3OISA 3BPMA 1U9QX 1NPZA 4I04A 4QBBA 4CDEB 4AXMA 1THEA 1YK8A 3RVWA 1KFXL 4AXLA 1YT7A 1YVBA 4X6HA 2IBIA 3OVXA 3BC3A 1AYUA 1AYWA 1AECA 1BQIA 1PPOA 3I06A 2PADA 3QJ3A 2DCBA 3IEJA 4I07A 2ATOA 3P5VA 3N4CA 1CJLA 2Y6EA 3O0UA 2HH5A 4CZWA 2O6XA 3PBHA 3H8BA 2B1NA 4X6IA 2OULA 4HWYA 2DJGB 4Q8HA 4CDDB 1CVZA 3PNRA 1VSNA 2P86A 3WXGA 1PPNA 3H89A 1EWPA 1F2AA 3OF9A 4YV8A 3BWKA 3WXFA 1POPA 3C9EA 2PNSA 1MEGA 1F29A 1ITOA 2VHSA 1GECE 3OVZA 5A24A 4QH6A 2R9NA 3KSEA 4PADA 2AUZA 2JQFR 3HWNA 3USVA 3DF0A 3IMAA 1GCBA 3ERVA 2DC9A 5F02A 2H7JA 3V6CA 1KHQA 1GMYA 1EF7A 1PADA 3B79A 1FH0A 5CVNB 2G6DA 3CBKA 3S3QA 5CVOB 3ZUAA 2FQ9A 4QRXA 3CH3X 2OP3A 3P5UA 4YYSA 2C0YA 4X6JA 4YYQA 5CVMA 1O0EA 3N3GA 4FK5A 4YYVA 2XU1A 1U9VA 1PPPA 2ARYA 1AU0A 1HUCB 2YJBA 2NQIA 2FRAA 2P7UA 4BQVA 3MHHA 3KWBX 4YVAA 2DZZA 2FUDA 2B1MA 3IUTA 2FT2A 1JQPA 1YALA 3P5WA 2OZ2A 4XUIA 2HD5A 1QXPA 1KFUL 4ZUXU 2PREA 1X9YA 2AYOA 2AYNA 7PCKA 2FTDA 3P5XA 3IV2A 1TU6A 1ME4A 2NQAA 1NQCA 1NB3A 2PBHA 2ACTA 4K7CA 1A6RA 1ZIVA
chains in the Genus database with same CATH superfamily
1NL6A 2FO5A 2JRIA 4RF1A 1EWLA 4RF0A 6PADA 4P6GA 3PDFA 1ICFA 2GHUA 2IPPB 4Q8GA 1K3BB 4OEMA 1QMYA 5JA7A 3PHWA 4BOSA 3TMPA 4RKXA 1DKIA 4KLBA 4D8EA 1S4VA 3BCNA 1CPJA 4PP2E 4BPVA 2AIMA 2BTWA 1PE6A 1QOLA 1MHWA 4OW0A 2DCAA 3H8CA 3IOQA 3N3KA 2DCCA 1EWOA 2E02A 3KFQA 1IWDA 1CQDA 4FJCA 4MM3B 3HD3A 2G7YA 2AU1A 3PHXA 1AU4A 3BOWA 3LXSA 3K8UA 1DF0A 3CBJA 3U8EA 3KKUA 4N4ZA 4REZA 1Y4HA 1PXVA 5PADA 2BU3A 1U9XA 2XU5A 2E01A 2Z84A 4BOZA 2F1GA 1U5IA 1ATKA 5CHVA 3MTNA 3LFYA 4N79A 5KO3A 4PT5A 2DJFB 5JH3A 2DC6A 3BPFA 1TLOA 3E1ZB 3HHAA 3PHUA 1YK7A 1CTEA 3KX1A 3MTVA 1TL9A 3O1GA 1CSBB 3KW9A 4RY2A 4BS6A 2WBFX 2E00A 4OELA 1U9WA 1SNKA 1EWMA 2FYEA 3BY4A 1SP4B 3MHSA 1MIRA 2BDLA 2FRQA 2G8EA 4CDCB 3NHEA 1AU2A 3RNVA 2YJ8A 4PP1A 4XZXA 4PI3A 8PCHA 1AYVA 1BY8A 2JQGR 3MP2A 4XR7A 4R3DA 1QDQA 4FIPA 4W5BA 3MORA 4P6EA 2R9FA 1STFE 3F75A 1PPDA 9PAPA 3GCBA 4MI7A 4ZTBA 4A5UA 3PW3A 1ZCMA 2E03A 4BOQA 1MEMA 3F5VA 4QRVA 2YJ9A 3O65A 2R9OA 2DC8A 1Q6KA 1AU3A 5CHTA 4BS5A 3AI8A 2R9CA 4OVZA 4OVZB 3K9MA 2XU4A 1NLJA 3BB7A 2GFOA 1MS6A 2BTWB 2YJ2A 3S3RA 4G54A 2G8JA 4GUAA 5FPWA 3PT2A 1ME3A 1BP4A 3WXEA 3QSDA 2DC7A 1M6DA 1CS8A 1KXRA 4QRGA 4W4UA 5EGWA 1CB5A 3OF8A 3PRPA 3V6EA 3K24A 2DZYA 5J94A 4HXDB 1XKGA 3RVVA 2DCDA 2P0RA 2YJCA 1UKFA 1F2BA 3KWZA 5EF4A 1BGOA 3BBAA 2AUXA 4WA6A 2NQGA 4MSXA 1PVJA 3M99A 4W5CA 4MZSA 3H7DA 4BSQA 3HHIA 1CV8A 3TNXA 2AVWA 2F7DA 4D8IA 1GLOA 4IUMA 2JTCA 2R6NA 1NB5A 4YYWA 2Y5BA 2HWKA 4MZOA 2XU3A 5JZEA 2AS8A 1DEUA 1Y08A 3D6SA 1MDWA 4DMXA 1PIPA 4I05A 2CB5A 3CH2X 3H6SA 2HHNA 2R9MA 2CIOA 3QT4A 2HXZA 1PCIA 3I3TA 5K16A 1AIMA 1VJVA 2NQDB 4YYUA 4CDFB 3RVXA 4YYRA 1PBHA 3C0RA 2BDZA 1KHPA 3IHPA 1F2CA 4DMYA 2VHFA 4N8WA 3OISA 3BPMA 1U9QX 1NPZA 4I04A 4QBBA 4CDEB 4AXMA 1THEA 1YK8A 3RVWA 1KFXL 2UZJA 4AXLA 1YT7A 1YVBA 4X6HA 2IBIA 3OVXA 2DOSA 3BC3A 4P16A 1AYUA 1AYWA 1AECA 1YZBA 3W30A 1BQIA 1PPOA 3I06A 2PADA 3QJ3A 2DCBA 3IEJA 4I07A 2ATOA 3MJ5A 3N4CA 3P5VA 1CJLA 2Y6EA 3O0UA 4IP3A 4BOPA 2HH5A 5EZQA 4CZWA 2O6XA 3PBHA 3H8BA 2B1NA 4X6IA 2OULA 4HWYA 2DJGB 4Q8HA 4CDDB 1CVZA 3PNRA 1VSNA 2P86A 3WXGA 5EZSA 1PPNA 3H89A 1EWPA 3B21A 1F2AA 3OF9A 4YV8A 3BWKA 3OQCA 3WXFA 3PSEA 1POPA 3C9EA 2PNSA 3E9SA 1MEGA 1F29A 1ITOA 2VHSA 1GECE 3OVZA 5A24A 4QH6A 2R9NA 3KSEA 4WURA 4PADA 2FE8A 2AUZA 2JQFR 3HWNA 3USVA 3DF0A 3IMAA 1GCBA 3ERVA 2DC9A 5F02A 2H7JA 3V6CA 4BOUA 1KHQA 1GMYA 1EF7A 1PADA 3B79A 1FH0A 5CVNB 2G6DA 3CBKA 3S3QA 5CVOB 3ZUAA 2FQ9A 4M0WA 4QRXA 2AGAA 3W31A 3CH3X 2OP3A 3P5UA 4RNAA 4YYSA 2J7QA 2C0YA 2J7QC 3TRKA 4X6JA 4YYQA 5CVMA 1O0EA 3N3GA 4FK5A 4YYVA 2XU1A 1U9VA 1PPPA 2ARYA 1AU0A 1HUCB 2YJBA 3ZNHA 2NQIA 2FRAA 2P7UA 4BQVA 3MHHA 3KWBX 4YVAA 2DZZA 2FUDA 3IFUA 2B1MA 3IUTA 2FT2A 1JQPA 1YALA 3PRMA 3P5WA 2OZ2A 4XUIA 2HD5A 5E6JA 1QXPA 1KFUL 4ZUXU 2PREA 1X9YA 2AYOA 2AYNA 7PCKA 4D8BA 2FTDA 3P5XA 3IV2A 1TU6A 1ME4A 2NQAA 1NQCA 1NB3A 2PBHA 2ACTA 4K7CA 1A6RA 1ZIVA
chains in the Genus database with same CATH topology
1NL6A 2FO5A 1EWLA 1W5RA 6PADA 4P6GA 3PDFA 1ICFA 2GHUA 2IPPB 4Q8GA 1K3BB 4OEMA 1QMYA 5JA7A 4KLBA 1S4VA 3BCNA 1CPJA 4PP2E 4BPVA 2AIMA 1PE6A 1QOLA 1MHWA 2DCAA 3H8CA 3IOQA 3N3KA 2DCCA 1EWOA 2E02A 3KFQA 1IWDA 1CQDA 4FJCA 3HD3A 2G7YA 2AU1A 1AU4A 3BOWA 3LXSA 3K8UA 1DF0A 3CBJA 3U8EA 3KKUA 4N4ZA 1Y4HA 1PXVA 5PADA 1U9XA 2XU5A 2E01A 2F1GA 1U5IA 1ATKA 5CHVA 3MTNA 3LFYA 4N79A 2DJFB 5JH3A 2DC6A 3BPFA 1TLOA 3E1ZB 3HHAA 1YK7A 1CTEA 3KX1A 1TL9A 3O1GA 1CSBB 3KW9A 4RY2A 4BS6A 2WBFX 2E00A 4OELA 1U9WA 1SNKA 1EWMA 2FYEA 4NV8A 1SP4B 3MHSA 1MIRA 2BDLA 2FRQA 2G8EA 4CDCB 3NHEA 1AU2A 2YJ8A 4PP1A 4PI3A 8PCHA 1AYVA 1BY8A 2JQGR 4XR7A 1QDQA 4FIPA 4W5BA 3MORA 4P6EA 2R9FA 1STFE 3F75A 1PPDA 9PAPA 3GCBA 3PW3A 1ZCMA 2E03A 1MEMA 3F5VA 4QRVA 2YJ9A 2R9OA 3D9WA 2DC8A 1Q6KA 1AU3A 5CHTA 4BS5A 3AI8A 2R9CA 3K9MA 2XU4A 1NLJA 2GFOA 1MS6A 2YJ2A 3S3RA 4G54A 2G8JA 5FPWA 1ME3A 1BP4A 3WXEA 3QSDA 2DC7A 1M6DA 1CS8A 1KXRA 4QRGA 4W4UA 5EGWA 1CB5A 3OF8A 3V6EA 3K24A 2DZYA 4GUZA 5J94A 4C5PA 1XKGA 3RVVA 2DCDA 2P0RA 2YJCA 5EF4A 1F2BA 3KWZA 1BGOA 2AUXA 4WA6A 2NQGA 4MSXA 1E2TA 3M99A 1GX3A 4W5CA 4MZSA 3H7DA 4BSQA 3HHIA 1CV8A 3TNXA 2AVWA 2F7DA 4BGFA 1GLOA 2R6NA 1NB5A 4YYWA 2Y5BA 1W6FA 4MZOA 2XU3A 2AS8A 1DEUA 1Y08A 3D6SA 1MDWA 4DMXA 2BSZA 1PIPA 2VFBA 4I05A 2CB5A 3CH2X 3H6SA 2HHNA 2R9MA 2CIOA 3QT4A 2HXZA 1PCIA 3I3TA 5K16A 1AIMA 1VJVA 2NQDB 4YYUA 4CDFB 3RVXA 4YYRA 1PBHA 2BDZA 1KHPA 3IHPA 1F2CA 4DMYA 2VHFA 4N8WA 3OISA 3BPMA 4NV7A 1U9QX 1NPZA 4I04A 4QBBA 4CDEB 4AXMA 1THEA 1YK8A 3RVWA 1KFXL 4AXLA 1YT7A 1YVBA 4X6HA 2IBIA 3OVXA 3BC3A 1AYUA 1AYWA 1AECA 1BQIA 1PPOA 3I06A 2PADA 3QJ3A 2DCBA 3IEJA 4I07A 2ATOA 3P5VA 3N4CA 1CJLA 2Y6EA 3O0UA 2HH5A 4CZWA 2O6XA 3PBHA 3H8BA 2B1NA 4X6IA 2OULA 4HWYA 2DJGB 4Q8HA 4CDDB 1CVZA 3PNRA 1VSNA 2P86A 3WXGA 1PPNA 3H89A 1EWPA 1F2AA 3OF9A 4YV8A 3BWKA 3WXFA 1POPA 3C9EA 2PNSA 1MEGA 1F29A 1ITOA 2VHSA 1GECE 3OVZA 5A24A 4QH6A 2R9NA 3KSEA 4PADA 2AUZA 2JQFR 3HWNA 4B55A 3USVA 3DF0A 3IMAA 1GCBA 3ERVA 2DC9A 5F02A 2H7JA 3V6CA 1KHQA 3LTWA 1GMYA 1EF7A 1PADA 3B79A 1FH0A 5CVNB 2G6DA 3CBKA 3S3QA 2VFCA 5CVOB 3ZUAA 2FQ9A 4QRXA 3CH3X 2OP3A 3P5UA 4YYSA 2C0YA 4X6JA 4YYQA 5CVMA 1O0EA 3N3GA 4FK5A 4YYVA 2XU1A 1U9VA 1PPPA 2ARYA 1AU0A 1HUCB 2YJBA 2NQIA 2FRAA 2P7UA 4BQVA 3MHHA 3KWBX 4YVAA 2DZZA 2FUDA 2B1MA 3IUTA 2FT2A 1JQPA 1YALA 3P5WA 2OZ2A 4XUIA 2HD5A 1QXPA 1KFUL 4ZUXU 2PREA 1X9YA 2AYOA 2AYNA 1W4TA 7PCKA 3P5XA 2FTDA 3IV2A 1TU6A 1ME4A 2NQAA 1NQCA 1NB3A 2PBHA 2ACTA 4K7CA 1A6RA 1ZIVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NL6 A;  2FO5 A;  1EWL A;  6PAD A;  4P6G A;  3PDF A;  1ICF A;  2GHU A;  2IPP B;  4Q8G A;  1K3B B;  4OEM A;  1QMY A;  5JA7 A;  4KLB A;  1S4V A;  3BCN A;  1CPJ A;  4PP2 E;  4BPV A;  2AIM A;  1PE6 A;  1QOL A;  1MHW A;  2DCA A;  3H8C A;  3IOQ A;  3N3K A;  2DCC A;  1EWO A;  2E02 A;  3KFQ A;  1IWD A;  1CQD A;  4FJC A;  3HD3 A;  2G7Y A;  2AU1 A;  1AU4 A;  3BOW A;  3LXS A;  3K8U A;  1DF0 A;  3CBJ A;  3U8E A;  3KKU A;  4N4Z A;  1Y4H A;  1PXV A;  5PAD A;  1U9X A;  2XU5 A;  2E01 A;  2F1G A;  1U5I A;  1ATK A;  5CHV A;  3MTN A;  3LFY A;  4N79 A;  2DJF B;  5JH3 A;  2DC6 A;  3BPF A;  1TLO A;  3E1Z B;  3HHA A;  1YK7 A;  1CTE A;  3KX1 A;  1TL9 A;  3O1G A;  1CSB B;  3KW9 A;  4RY2 A;  4BS6 A;  2WBF X;  2E00 A;  4OEL A;  1U9W A;  1SNK A;  1EWM A;  2FYE A;  1SP4 B;  3MHS A;  1MIR A;  2BDL A;  2FRQ A;  2G8E A;  4CDC B;  3NHE A;  1AU2 A;  2YJ8 A;  4PP1 A;  4PI3 A;  8PCH A;  1AYV A;  1BY8 A;  2JQG R;  4XR7 A;  1QDQ A;  4FIP A;  4W5B A;  3MOR A;  4P6E A;  2R9F A;  1STF E;  3F75 A;  1PPD A;  9PAP A;  3GCB A;  3PW3 A;  1ZCM A;  2E03 A;  1MEM A;  3F5V A;  4QRV A;  2YJ9 A;  2R9O A;  2DC8 A;  1Q6K A;  1AU3 A;  5CHT A;  4BS5 A;  3AI8 A;  2R9C A;  3K9M A;  2XU4 A;  1NLJ A;  2GFO A;  1MS6 A;  2YJ2 A;  3S3R A;  4G54 A;  2G8J A;  5FPW A;  1ME3 A;  1BP4 A;  3WXE A;  3QSD A;  2DC7 A;  1M6D A;  1CS8 A;  1KXR A;  4QRG A;  4W4U A;  5EGW A;  1CB5 A;  3OF8 A;  3V6E A;  3K24 A;  2DZY A;  5J94 A;  1XKG A;  3RVV A;  2DCD A;  2P0R A;  2YJC A;  5EF4 A;  1F2B A;  3KWZ A;  1BGO A;  2AUX A;  4WA6 A;  2NQG A;  4MSX A;  3M99 A;  4W5C A;  4MZS A;  3H7D A;  4BSQ A;  3HHI A;  1CV8 A;  3TNX A;  2AVW A;  2F7D A;  1GLO A;  2R6N A;  1NB5 A;  4YYW A;  2Y5B A;  4MZO A;  2XU3 A;  2AS8 A;  1DEU A;  1Y08 A;  3D6S A;  1MDW A;  4DMX A;  1PIP A;  4I05 A;  2CB5 A;  3CH2 X;  3H6S A;  2HHN A;  2R9M A;  2CIO A;  3QT4 A;  2HXZ A;  1PCI A;  3I3T A;  5K16 A;  1AIM A;  1VJV A;  2NQD B;  4YYU A;  4CDF B;  3RVX A;  4YYR A;  1PBH A;  2BDZ A;  1KHP A;  3IHP A;  1F2C A;  4DMY A;  2VHF A;  4N8W A;  3OIS A;  3BPM A;  1U9Q X;  1NPZ A;  4I04 A;  4QBB A;  4CDE B;  4AXM A;  1THE A;  1YK8 A;  3RVW A;  1KFX L;  4AXL A;  1YT7 A;  1YVB A;  4X6H A;  2IBI A;  3OVX A;  3BC3 A;  1AYU A;  1AYW A;  1AEC A;  1BQI A;  1PPO A;  3I06 A;  2PAD A;  3QJ3 A;  2DCB A;  3IEJ A;  4I07 A;  2ATO A;  3P5V A;  3N4C A;  1CJL A;  2Y6E A;  3O0U A;  2HH5 A;  4CZW A;  2O6X A;  3PBH A;  3H8B A;  2B1N A;  4X6I A;  2OUL A;  4HWY A;  2DJG B;  4Q8H A;  4CDD B;  1CVZ A;  3PNR A;  1VSN A;  2P86 A;  3WXG A;  1PPN A;  3H89 A;  1EWP A;  1F2A A;  3OF9 A;  4YV8 A;  3BWK A;  3WXF A;  1POP A;  3C9E A;  2PNS A;  1MEG A;  1F29 A;  1ITO A;  2VHS A;  1GEC E;  3OVZ A;  5A24 A;  4QH6 A;  2R9N A;  3KSE A;  4PAD A;  2AUZ A;  2JQF R;  3HWN A;  3USV A;  3DF0 A;  3IMA A;  1GCB A;  3ERV A;  2DC9 A;  5F02 A;  2H7J A;  3V6C A;  1KHQ A;  1GMY A;  1EF7 A;  1PAD A;  3B79 A;  1FH0 A;  5CVN B;  2G6D A;  3CBK A;  3S3Q A;  5CVO B;  3ZUA A;  2FQ9 A;  4QRX A;  3CH3 X;  2OP3 A;  3P5U A;  4YYS A;  2C0Y A;  4X6J A;  4YYQ A;  5CVM A;  1O0E A;  3N3G A;  4FK5 A;  4YYV A;  2XU1 A;  1U9V A;  1PPP A;  2ARY A;  1AU0 A;  1HUC B;  2YJB A;  2NQI A;  2FRA A;  2P7U A;  4BQV A;  3MHH A;  3KWB X;  4YVA A;  2DZZ A;  2FUD A;  2B1M A;  3IUT A;  2FT2 A;  1JQP A;  1YAL A;  3P5W A;  2OZ2 A;  4XUI A;  2HD5 A;  1QXP A;  1KFU L;  4ZUX U;  2PRE A;  1X9Y A;  2AYO A;  2AYN A;  7PCK A;  2FTD A;  3P5X A;  3IV2 A;  1TU6 A;  1ME4 A;  2NQA A;  1NQC A;  1NB3 A;  2PBH A;  2ACT A;  4K7C A;  1A6R A;  1ZIV A; 
#chains in the Genus database with same CATH topology
 1NL6 A;  2FO5 A;  2JRI A;  4RF1 A;  1EWL A;  4RF0 A;  6PAD A;  4P6G A;  3PDF A;  1ICF A;  2GHU A;  2IPP B;  4Q8G A;  1K3B B;  4OEM A;  1QMY A;  5JA7 A;  3PHW A;  4BOS A;  3TMP A;  4RKX A;  1DKI A;  4KLB A;  4D8E A;  1S4V A;  3BCN A;  1CPJ A;  4PP2 E;  4BPV A;  2AIM A;  2BTW A;  1PE6 A;  1QOL A;  1MHW A;  4OW0 A;  2DCA A;  3H8C A;  3IOQ A;  3N3K A;  2DCC A;  1EWO A;  2E02 A;  3KFQ A;  1IWD A;  1CQD A;  4FJC A;  4MM3 B;  3HD3 A;  2G7Y A;  2AU1 A;  3PHX A;  1AU4 A;  3BOW A;  3LXS A;  3K8U A;  1DF0 A;  3CBJ A;  3U8E A;  3KKU A;  4N4Z A;  4REZ A;  1Y4H A;  1PXV A;  5PAD A;  2BU3 A;  1U9X A;  2XU5 A;  2E01 A;  2Z84 A;  4BOZ A;  2F1G A;  1U5I A;  1ATK A;  5CHV A;  3MTN A;  3LFY A;  4N79 A;  5KO3 A;  4PT5 A;  2DJF B;  5JH3 A;  2DC6 A;  3BPF A;  1TLO A;  3E1Z B;  3HHA A;  3PHU A;  1YK7 A;  1CTE A;  3KX1 A;  3MTV A;  1TL9 A;  3O1G A;  1CSB B;  3KW9 A;  4RY2 A;  4BS6 A;  2WBF X;  2E00 A;  4OEL A;  1U9W A;  1SNK A;  1EWM A;  2FYE A;  3BY4 A;  1SP4 B;  3MHS A;  1MIR A;  2BDL A;  2FRQ A;  2G8E A;  4CDC B;  3NHE A;  1AU2 A;  3RNV A;  2YJ8 A;  4PP1 A;  4XZX A;  4PI3 A;  8PCH A;  1AYV A;  1BY8 A;  2JQG R;  3MP2 A;  4XR7 A;  4R3D A;  1QDQ A;  4FIP A;  4W5B A;  3MOR A;  4P6E A;  2R9F A;  1STF E;  3F75 A;  1PPD A;  9PAP A;  3GCB A;  4MI7 A;  4ZTB A;  4A5U A;  3PW3 A;  1ZCM A;  2E03 A;  4BOQ A;  1MEM A;  3F5V A;  4QRV A;  2YJ9 A;  3O65 A;  2R9O A;  2DC8 A;  1Q6K A;  1AU3 A;  5CHT A;  4BS5 A;  3AI8 A;  2R9C A;  4OVZ A;  4OVZ B;  3K9M A;  2XU4 A;  1NLJ A;  3BB7 A;  2GFO A;  1MS6 A;  2BTW B;  2YJ2 A;  3S3R A;  4G54 A;  2G8J A;  4GUA A;  5FPW A;  3PT2 A;  1ME3 A;  1BP4 A;  3WXE A;  3QSD A;  2DC7 A;  1M6D A;  1CS8 A;  1KXR A;  4QRG A;  4W4U A;  5EGW A;  1CB5 A;  3OF8 A;  3PRP A;  3V6E A;  3K24 A;  2DZY A;  5J94 A;  4HXD B;  1XKG A;  3RVV A;  2DCD A;  2P0R A;  2YJC A;  1UKF A;  1F2B A;  3KWZ A;  5EF4 A;  1BGO A;  3BBA A;  2AUX A;  4WA6 A;  2NQG A;  4MSX A;  1PVJ A;  3M99 A;  4W5C A;  4MZS A;  3H7D A;  4BSQ A;  3HHI A;  1CV8 A;  3TNX A;  2AVW A;  2F7D A;  4D8I A;  1GLO A;  4IUM A;  2JTC A;  2R6N A;  1NB5 A;  4YYW A;  2Y5B A;  2HWK A;  4MZO A;  2XU3 A;  5JZE A;  2AS8 A;  1DEU A;  1Y08 A;  3D6S A;  1MDW A;  4DMX A;  1PIP A;  4I05 A;  2CB5 A;  3CH2 X;  3H6S A;  2HHN A;  2R9M A;  2CIO A;  3QT4 A;  2HXZ A;  1PCI A;  3I3T A;  5K16 A;  1AIM A;  1VJV A;  2NQD B;  4YYU A;  4CDF B;  3RVX A;  4YYR A;  1PBH A;  3C0R A;  2BDZ A;  1KHP A;  3IHP A;  1F2C A;  4DMY A;  2VHF A;  4N8W A;  3OIS A;  3BPM A;  1U9Q X;  1NPZ A;  4I04 A;  4QBB A;  4CDE B;  4AXM A;  1THE A;  1YK8 A;  3RVW A;  1KFX L;  2UZJ A;  4AXL A;  1YT7 A;  1YVB A;  4X6H A;  2IBI A;  3OVX A;  2DOS A;  3BC3 A;  4P16 A;  1AYU A;  1AYW A;  1AEC A;  1YZB A;  3W30 A;  1BQI A;  1PPO A;  3I06 A;  2PAD A;  3QJ3 A;  2DCB A;  3IEJ A;  4I07 A;  2ATO A;  3MJ5 A;  3N4C A;  3P5V A;  1CJL A;  2Y6E A;  3O0U A;  4IP3 A;  4BOP A;  2HH5 A;  5EZQ A;  4CZW A;  2O6X A;  3PBH A;  3H8B A;  2B1N A;  4X6I A;  2OUL A;  4HWY A;  2DJG B;  4Q8H A;  4CDD B;  1CVZ A;  3PNR A;  1VSN A;  2P86 A;  3WXG A;  5EZS A;  1PPN A;  3H89 A;  1EWP A;  3B21 A;  1F2A A;  3OF9 A;  4YV8 A;  3BWK A;  3OQC A;  3WXF A;  3PSE A;  1POP A;  3C9E A;  2PNS A;  3E9S A;  1MEG A;  1F29 A;  1ITO A;  2VHS A;  1GEC E;  3OVZ A;  5A24 A;  4QH6 A;  2R9N A;  3KSE A;  4WUR A;  4PAD A;  2FE8 A;  2AUZ A;  2JQF R;  3HWN A;  3USV A;  3DF0 A;  3IMA A;  1GCB A;  3ERV A;  2DC9 A;  5F02 A;  2H7J A;  3V6C A;  4BOU A;  1KHQ A;  1GMY A;  1EF7 A;  1PAD A;  3B79 A;  1FH0 A;  5CVN B;  2G6D A;  3CBK A;  3S3Q A;  5CVO B;  3ZUA A;  2FQ9 A;  4M0W A;  4QRX A;  2AGA A;  3W31 A;  3CH3 X;  2OP3 A;  3P5U A;  4RNA A;  4YYS A;  2J7Q A;  2C0Y A;  2J7Q C;  3TRK A;  4X6J A;  4YYQ A;  5CVM A;  1O0E A;  3N3G A;  4FK5 A;  4YYV A;  2XU1 A;  1U9V A;  1PPP A;  2ARY A;  1AU0 A;  1HUC B;  2YJB A;  3ZNH A;  2NQI A;  2FRA A;  2P7U A;  4BQV A;  3MHH A;  3KWB X;  4YVA A;  2DZZ A;  2FUD A;  3IFU A;  2B1M A;  3IUT A;  2FT2 A;  1JQP A;  1YAL A;  3PRM A;  3P5W A;  2OZ2 A;  4XUI A;  2HD5 A;  5E6J A;  1QXP A;  1KFU L;  4ZUX U;  2PRE A;  1X9Y A;  2AYO A;  2AYN A;  7PCK A;  4D8B A;  2FTD A;  3P5X A;  3IV2 A;  1TU6 A;  1ME4 A;  2NQA A;  1NQC A;  1NB3 A;  2PBH A;  2ACT A;  4K7C A;  1A6R A;  1ZIV A; 
#chains in the Genus database with same CATH homology
 1NL6 A;  2FO5 A;  1EWL A;  1W5R A;  6PAD A;  4P6G A;  3PDF A;  1ICF A;  2GHU A;  2IPP B;  4Q8G A;  1K3B B;  4OEM A;  1QMY A;  5JA7 A;  4KLB A;  1S4V A;  3BCN A;  1CPJ A;  4PP2 E;  4BPV A;  2AIM A;  1PE6 A;  1QOL A;  1MHW A;  2DCA A;  3H8C A;  3IOQ A;  3N3K A;  2DCC A;  1EWO A;  2E02 A;  3KFQ A;  1IWD A;  1CQD A;  4FJC A;  3HD3 A;  2G7Y A;  2AU1 A;  1AU4 A;  3BOW A;  3LXS A;  3K8U A;  1DF0 A;  3CBJ A;  3U8E A;  3KKU A;  4N4Z A;  1Y4H A;  1PXV A;  5PAD A;  1U9X A;  2XU5 A;  2E01 A;  2F1G A;  1U5I A;  1ATK A;  5CHV A;  3MTN A;  3LFY A;  4N79 A;  2DJF B;  5JH3 A;  2DC6 A;  3BPF A;  1TLO A;  3E1Z B;  3HHA A;  1YK7 A;  1CTE A;  3KX1 A;  1TL9 A;  3O1G A;  1CSB B;  3KW9 A;  4RY2 A;  4BS6 A;  2WBF X;  2E00 A;  4OEL A;  1U9W A;  1SNK A;  1EWM A;  2FYE A;  4NV8 A;  1SP4 B;  3MHS A;  1MIR A;  2BDL A;  2FRQ A;  2G8E A;  4CDC B;  3NHE A;  1AU2 A;  2YJ8 A;  4PP1 A;  4PI3 A;  8PCH A;  1AYV A;  1BY8 A;  2JQG R;  4XR7 A;  1QDQ A;  4FIP A;  4W5B A;  3MOR A;  4P6E A;  2R9F A;  1STF E;  3F75 A;  1PPD A;  9PAP A;  3GCB A;  3PW3 A;  1ZCM A;  2E03 A;  1MEM A;  3F5V A;  4QRV A;  2YJ9 A;  2R9O A;  3D9W A;  2DC8 A;  1Q6K A;  1AU3 A;  5CHT A;  4BS5 A;  3AI8 A;  2R9C A;  3K9M A;  2XU4 A;  1NLJ A;  2GFO A;  1MS6 A;  2YJ2 A;  3S3R A;  4G54 A;  2G8J A;  5FPW A;  1ME3 A;  1BP4 A;  3WXE A;  3QSD A;  2DC7 A;  1M6D A;  1CS8 A;  1KXR A;  4QRG A;  4W4U A;  5EGW A;  1CB5 A;  3OF8 A;  3V6E A;  3K24 A;  2DZY A;  4GUZ A;  5J94 A;  4C5P A;  1XKG A;  3RVV A;  2DCD A;  2P0R A;  2YJC A;  5EF4 A;  1F2B A;  3KWZ A;  1BGO A;  2AUX A;  4WA6 A;  2NQG A;  4MSX A;  1E2T A;  3M99 A;  1GX3 A;  4W5C A;  4MZS A;  3H7D A;  4BSQ A;  3HHI A;  1CV8 A;  3TNX A;  2AVW A;  2F7D A;  4BGF A;  1GLO A;  2R6N A;  1NB5 A;  4YYW A;  2Y5B A;  1W6F A;  4MZO A;  2XU3 A;  2AS8 A;  1DEU A;  1Y08 A;  3D6S A;  1MDW A;  4DMX A;  2BSZ A;  1PIP A;  2VFB A;  4I05 A;  2CB5 A;  3CH2 X;  3H6S A;  2HHN A;  2R9M A;  2CIO A;  3QT4 A;  2HXZ A;  1PCI A;  3I3T A;  5K16 A;  1AIM A;  1VJV A;  2NQD B;  4YYU A;  4CDF B;  3RVX A;  4YYR A;  1PBH A;  2BDZ A;  1KHP A;  3IHP A;  1F2C A;  4DMY A;  2VHF A;  4N8W A;  3OIS A;  3BPM A;  4NV7 A;  1U9Q X;  1NPZ A;  4I04 A;  4QBB A;  4CDE B;  4AXM A;  1THE A;  1YK8 A;  3RVW A;  1KFX L;  4AXL A;  1YT7 A;  1YVB A;  4X6H A;  2IBI A;  3OVX A;  3BC3 A;  1AYU A;  1AYW A;  1AEC A;  1BQI A;  1PPO A;  3I06 A;  2PAD A;  3QJ3 A;  2DCB A;  3IEJ A;  4I07 A;  2ATO A;  3P5V A;  3N4C A;  1CJL A;  2Y6E A;  3O0U A;  2HH5 A;  4CZW A;  2O6X A;  3PBH A;  3H8B A;  2B1N A;  4X6I A;  2OUL A;  4HWY A;  2DJG B;  4Q8H A;  4CDD B;  1CVZ A;  3PNR A;  1VSN A;  2P86 A;  3WXG A;  1PPN A;  3H89 A;  1EWP A;  1F2A A;  3OF9 A;  4YV8 A;  3BWK A;  3WXF A;  1POP A;  3C9E A;  2PNS A;  1MEG A;  1F29 A;  1ITO A;  2VHS A;  1GEC E;  3OVZ A;  5A24 A;  4QH6 A;  2R9N A;  3KSE A;  4PAD A;  2AUZ A;  2JQF R;  3HWN A;  4B55 A;  3USV A;  3DF0 A;  3IMA A;  1GCB A;  3ERV A;  2DC9 A;  5F02 A;  2H7J A;  3V6C A;  1KHQ A;  3LTW A;  1GMY A;  1EF7 A;  1PAD A;  3B79 A;  1FH0 A;  5CVN B;  2G6D A;  3CBK A;  3S3Q A;  2VFC A;  5CVO B;  3ZUA A;  2FQ9 A;  4QRX A;  3CH3 X;  2OP3 A;  3P5U A;  4YYS A;  2C0Y A;  4X6J A;  4YYQ A;  5CVM A;  1O0E A;  3N3G A;  4FK5 A;  4YYV A;  2XU1 A;  1U9V A;  1PPP A;  2ARY A;  1AU0 A;  1HUC B;  2YJB A;  2NQI A;  2FRA A;  2P7U A;  4BQV A;  3MHH A;  3KWB X;  4YVA A;  2DZZ A;  2FUD A;  2B1M A;  3IUT A;  2FT2 A;  1JQP A;  1YAL A;  3P5W A;  2OZ2 A;  4XUI A;  2HD5 A;  1QXP A;  1KFU L;  4ZUX U;  2PRE A;  1X9Y A;  2AYO A;  2AYN A;  1W4T A;  7PCK A;  3P5X A;  2FTD A;  3IV2 A;  1TU6 A;  1ME4 A;  2NQA A;  1NQC A;  1NB3 A;  2PBH A;  2ACT A;  4K7C A;  1A6R A;  1ZIV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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