2YJCA

Cathepsin l with a nitrile inhibitor
Total Genus 74
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
74
sequence length
220
structure length
219
Chain Sequence
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTSDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Halogen Bonding at the Active Sites of Human Cathepsin L and Mek1 Kinase: Efficient Interactions in Different Environments.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords CATHEPSIN L1
total genus 74
structure length 219
sequence length 220
ec nomenclature ec 3.4.22.15: Cathepsin L.
pdb deposition date 2011-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 2yjcA00
3IEJA 1AYWA 1YK8A 2E01A 1EWOA 1Y08A 1EF7A 3KKUA 2PREA 1ZIVA 1U9QX 2P86A 5CHVA 4YYVA 4PI3A 4W5BA 1U9WA 1Y4HA 1ITOA 3PNRA 2AS8A 4N4ZA 5J94A 2GHUA 2VHFA 3NHEA 2CB5A 4OEMA 2FUDA 3MORA 3CBKA 2OP3A 8PCHA 2AU1A 2XU3A 1Q6KA 1IWDA 3O1GA 3CH2X 3KWZA 3QJ3A 4YYRA 1AECA 2ATOA 1PBHA 5EF4A 2R9FA 5EGWA 4BSQA 2B1MA 3IOQA 2G7YA 1MEMA 3KW9A 4MZSA 2P7UA 3PBHA 2DC6A 3BPMA 4QH6A 1GMYA 4I07A 1PADA 4Q8GA 1AU4A 2AVWA 5K16A 1YT7A 3WXEA 3MTNA 1CB5A 2AIMA 3S3RA 1PPOA 1AU0A 5F02A 3N4CA 4I05A 3IMAA 3HWNA 5JH3A 2WBFX 4XUIA 2YJ8A 3BC3A 2NQAA 1THEA 1POPA 3H89A 2JQGR 1PPDA 5CHTA 1VJVA 3F75A 1BP4A 2DCAA 3I3TA 3B79A 1PPNA 3K8UA 4RY2A 5PADA 3WXGA 3BPFA 1KHQA 2BDZA 1NB5A 5CVOB 2NQDB 1AYVA 1EWLA 4W5CA 3IUTA 1KFUL 1ME4A 5CVMA 9PAPA 4I04A 3KX1A 1TU6A 3BWKA 4G54A 2HH5A 2C0YA 2FT2A 2YJCA 4BPVA 1SP4B 3LXSA 4CZWA 2FRQA 5CVNB 1GECE 3V6CA 4MZOA 2IBIA 1AYUA 2YJ9A 3QT4A 2HHNA 3QSDA 3S3QA 2FO5A 1CV8A 2ACTA 2NQGA 2R6NA 4X6IA 1CPJA 1QOLA 2Y5BA 4YYSA 3P5VA 1CVZA 3D6SA 4BQVA 1QMYA 3H8BA 3DF0A 1F2BA 3HHAA 2AYNA 2G8EA 1AU3A 2FTDA 2FRAA 2YJ2A 3P5UA 5A24A 2XU5A 4OELA 1AU2A 1NB3A 2IPPB 4X6JA 2FYEA 1EWPA 1NLJA 2GFOA 2R9NA 1JQPA 3H7DA 1DEUA 1YVBA 1TL9A 2DC7A 1QXPA 4BS6A 2O6XA 3USVA 2DCCA 3RVVA 1KXRA 1EWMA 3ERVA 1GCBA 1MEGA 1O0EA 1F29A 2JQFR 3K24A 3OVZA 3N3KA 1U5IA 2DZYA 1S4VA 2R9MA 1DF0A 1YALA 1NQCA 4XR7A 3GCBA 1AIMA 1NPZA 4W4UA 4WA6A 1FH0A 2OZ2A 3OF8A 2DJGB 2G8JA 2DJFB 1VSNA 4YVAA 4Q8HA 1F2AA 1YK7A 2B1NA 2AYOA 1ME3A 3U8EA 2VHSA 2PBHA 1CJLA 1KFXL 6PADA 2F1GA 4AXMA 2HD5A 4N79A 1CS8A 2DC9A 1PPPA 4QRGA 2OULA 2XU4A 4PP2E 4QRVA 4P6GA 3KWBX 2NQIA 3CH3X 1BY8A 4MSXA 2BDLA 4CDCB 2AUXA 2E00A 4AXLA 4YYWA 1CSBB 1CQDA 3PW3A 1U9VA 3HD3A 3MHHA 5FPWA 2FQ9A 4ZUXU 4QRXA 4YV8A 1GLOA 1HUCB 3E1ZB 3OISA 1PXVA 2F7DA 3PDFA 3KFQA 2HXZA 3RVWA 1ICFA 2ARYA 4FIPA 1KHPA 2E02A 1U9XA 3WXFA 4DMXA 3H6SA 1A6RA 2R9OA 2DZZA 3P5WA 4BS5A 3MHSA 1SNKA 3RVXA 3V6EA 2PADA 4PADA 4HWYA 3M99A 3BOWA 2PNSA 1MDWA 4P6EA 4FK5A 3ZUAA 4YYUA 5JA7A 3I06A 4CDEB 4PP1A 4KLBA 1X9YA 3IV2A 1M6DA 2E03A 3BCNA 4FJCA 7PCKA 1K3BB 1ATKA 2YJBA 4CDFB 2P0RA 3HHIA 3F5VA 2XU1A 3C9EA 4QBBA 1XKGA 3LFYA 4CDDB 1MIRA 2DCBA 3K9MA 3H8CA 1ZCMA 1PIPA 1MS6A 1F2CA 3P5XA 2DCDA 2DC8A 1BQIA 2H7JA 3CBJA 4DMYA 1NL6A 3KSEA 1QDQA 4X6HA 3O0UA 2G6DA 3TNXA 2AUZA 4K7CA 4YYQA 3OF9A 2R9CA 1MHWA 1CTEA 2CIOA 4N8WA 2Y6EA 3N3GA 1PE6A 1TLOA 1PCIA 3OVXA 1BGOA 3IHPA 1STFE 3AI8A
chains in the Genus database with same CATH superfamily
3IEJA 1AYWA 1YK8A 2E01A 1EWOA 1Y08A 1EF7A 3KKUA 2PREA 1ZIVA 1U9QX 2P86A 4BOSA 5CHVA 4YYVA 4PI3A 3PSEA 1U9WA 4W5BA 1Y4HA 1ITOA 3PNRA 2AS8A 4N4ZA 5J94A 2GHUA 4BOUA 2VHFA 3NHEA 2CB5A 4OEMA 2FUDA 3MORA 3CBKA 3MJ5A 2OP3A 8PCHA 2AGAA 2AU1A 2JRIA 4RKXA 2XU3A 1Q6KA 1IWDA 4XZXA 3O1GA 4OW0A 3CH2X 2J7QC 3KWZA 3QJ3A 4YYRA 1AECA 2ATOA 1PBHA 5EF4A 2R9FA 5EGWA 4BSQA 2B1MA 3IOQA 2G7YA 1MEMA 3KW9A 4MZSA 2P7UA 3PBHA 2DC6A 3BPMA 4QH6A 1GMYA 4I07A 1PADA 4Q8GA 1AU4A 2AVWA 2Z84A 5K16A 1YT7A 3WXEA 3MTNA 1CB5A 2AIMA 3S3RA 1PPOA 1AU0A 4MM3B 5F02A 3N4CA 4I05A 3IMAA 3MTVA 3HWNA 5JH3A 2WBFX 4XUIA 2YJ8A 3BC3A 2NQAA 1THEA 4BOPA 1POPA 3H89A 2JQGR 1PPDA 5CHTA 1VJVA 3F75A 3BB7A 1BP4A 2DCAA 3I3TA 3B79A 4WURA 1PPNA 4ZTBA 5KO3A 3K8UA 4RY2A 1PVJA 5PADA 3WXGA 3BPFA 1KHQA 2BDZA 1NB5A 5CVOB 3MP2A 2NQDB 1AYVA 1EWLA 4W5CA 3IUTA 1KFUL 1ME4A 5CVMA 9PAPA 4I04A 3KX1A 1TU6A 3BWKA 4G54A 2HH5A 2C0YA 2FT2A 2YJCA 4BPVA 1SP4B 3LXSA 5EZSA 3PHWA 5E6JA 4CZWA 2FRQA 5CVNB 1GECE 3V6CA 4MZOA 2IBIA 1AYUA 2YJ9A 3QT4A 2HHNA 4REZA 3QSDA 3S3QA 3OQCA 2FO5A 1CV8A 2UZJA 2ACTA 2NQGA 4MI7A 2R6NA 4X6IA 1CPJA 1QOLA 2Y5BA 4YYSA 3P5VA 1CVZA 3BY4A 4BOQA 1YZBA 3D6SA 4BQVA 1QMYA 3H8BA 3DF0A 1F2BA 3HHAA 2AYNA 2G8EA 1AU3A 2FTDA 2FRAA 2YJ2A 3P5UA 5A24A 2XU5A 4OELA 1AU2A 1NB3A 2IPPB 4X6JA 2FYEA 1EWPA 3E9SA 1NLJA 2GFOA 2R9NA 1JQPA 3BBAA 3H7DA 4GUAA 1DEUA 1YVBA 1TL9A 3PHXA 2DC7A 1QXPA 3TRKA 2O6XA 4BS6A 3USVA 2FE8A 2DCCA 3IFUA 1KXRA 3RVVA 1EWMA 3ERVA 1GCBA 1MEGA 1O0EA 1F29A 2JQFR 3K24A 3OVZA 3N3KA 1U5IA 2DZYA 1S4VA 2R9MA 1DF0A 1YALA 1NQCA 3PRMA 4XR7A 3GCBA 1AIMA 1NPZA 4PT5A 4W4UA 4WA6A 4IP3A 2BU3A 1FH0A 2OZ2A 3OF8A 2DJGB 2J7QA 2G8JA 2DJFB 1VSNA 4YVAA 4Q8HA 1F2AA 1YK7A 2B1NA 2AYOA 1ME3A 3U8EA 2VHSA 2PBHA 1CJLA 4D8BA 1KFXL 6PADA 2F1GA 4AXMA 2HD5A 4N79A 1CS8A 2DC9A 3PRPA 1PPPA 3W31A 4QRGA 2OULA 2XU4A 2JTCA 4PP2E 4QRVA 4P6GA 3KWBX 2NQIA 3CH3X 1BY8A 4MSXA 2BDLA 4RF1A 4CDCB 2AUXA 2E00A 3TMPA 4AXLA 4YYWA 1CSBB 1CQDA 2BTWB 3PW3A 1U9VA 3HD3A 3MHHA 5FPWA 2FQ9A 2BTWA 4ZUXU 4QRXA 4YV8A 1GLOA 1HUCB 3E1ZB 3OISA 1PXVA 4BOZA 1DKIA 2F7DA 3PDFA 3KFQA 2HXZA 3RVWA 1ICFA 2ARYA 4FIPA 1KHPA 2E02A 1U9XA 3WXFA 4DMXA 3H6SA 1A6RA 2R9OA 2DZZA 3P5WA 1UKFA 4BS5A 3MHSA 1SNKA 3RVXA 3V6EA 2PADA 4PADA 4HWYA 3M99A 3BOWA 2PNSA 1MDWA 4RNAA 4P6EA 4FK5A 4IUMA 3ZUAA 3PT2A 4YYUA 5JA7A 3I06A 4CDEB 4PP1A 3ZNHA 4KLBA 1X9YA 3IV2A 1M6DA 2E03A 3BCNA 4FJCA 7PCKA 1K3BB 1ATKA 2YJBA 4CDFB 2HWKA 2P0RA 3HHIA 3F5VA 2XU1A 4D8IA 3C9EA 3O65A 4QBBA 1XKGA 3LFYA 4CDDB 1MIRA 2DOSA 2DCBA 5EZQA 4A5UA 3K9MA 3H8CA 1ZCMA 4OVZB 1PIPA 1MS6A 1F2CA 3P5XA 5JZEA 2DCDA 3PHUA 2DC8A 4D8EA 1BQIA 4P16A 2H7JA 4OVZA 3CBJA 4DMYA 4RF0A 1NL6A 3KSEA 3B21A 1QDQA 3W30A 4X6HA 3O0UA 2G6DA 3TNXA 3C0RA 2AUZA 4K7CA 4M0WA 4R3DA 3RNVA 4YYQA 3OF9A 2R9CA 1MHWA 1CTEA 2CIOA 4N8WA 2Y6EA 3N3GA 1PE6A 1TLOA 4HXDB 1PCIA 3OVXA 1BGOA 3IHPA 1STFE 3AI8A
chains in the Genus database with same CATH topology
3IEJA 1AYWA 1YK8A 2E01A 1EWOA 1Y08A 1EF7A 3KKUA 2PREA 1ZIVA 1U9QX 3D9WA 1E2TA 2P86A 5CHVA 4YYVA 4PI3A 4W5BA 1U9WA 1Y4HA 1ITOA 4B55A 3PNRA 2AS8A 4N4ZA 5J94A 2GHUA 2VHFA 3NHEA 2CB5A 4OEMA 2FUDA 3MORA 3CBKA 2OP3A 1W6FA 8PCHA 2AU1A 2XU3A 1Q6KA 1IWDA 3O1GA 3CH2X 3KWZA 3QJ3A 4YYRA 1AECA 2ATOA 1PBHA 5EF4A 2R9FA 5EGWA 4BSQA 2B1MA 3IOQA 2G7YA 1MEMA 3KW9A 4MZSA 2P7UA 3PBHA 2DC6A 3BPMA 4QH6A 1GMYA 4I07A 1PADA 4Q8GA 1AU4A 1W5RA 2AVWA 5K16A 1YT7A 3WXEA 3MTNA 1CB5A 2AIMA 3S3RA 1PPOA 1AU0A 5F02A 3N4CA 4I05A 3IMAA 3HWNA 5JH3A 2WBFX 4XUIA 2YJ8A 3BC3A 2NQAA 1THEA 1POPA 3H89A 2JQGR 1PPDA 5CHTA 1VJVA 3F75A 1BP4A 2DCAA 3I3TA 3B79A 1PPNA 3K8UA 4RY2A 5PADA 3WXGA 3BPFA 1KHQA 2BDZA 1NB5A 5CVOB 2NQDB 1AYVA 1EWLA 4W5CA 3IUTA 1KFUL 1ME4A 5CVMA 9PAPA 4I04A 2BSZA 3KX1A 1TU6A 3BWKA 4G54A 2HH5A 2C0YA 2FT2A 2YJCA 4BPVA 1SP4B 3LXSA 4CZWA 2FRQA 5CVNB 1GECE 3V6CA 4MZOA 2IBIA 1AYUA 2VFCA 2YJ9A 3QT4A 2HHNA 1W4TA 3QSDA 3S3QA 2FO5A 1CV8A 2ACTA 2NQGA 2R6NA 4X6IA 1CPJA 1QOLA 2Y5BA 4YYSA 3P5VA 1CVZA 3D6SA 4BQVA 1QMYA 3H8BA 3DF0A 1F2BA 3HHAA 2AYNA 2G8EA 4BGFA 1AU3A 2FTDA 2FRAA 2YJ2A 3P5UA 5A24A 2XU5A 4OELA 1AU2A 1NB3A 2IPPB 4X6JA 2FYEA 1EWPA 1NLJA 2GFOA 2R9NA 1JQPA 3H7DA 1DEUA 1YVBA 1TL9A 2DC7A 1QXPA 4BS6A 2O6XA 3USVA 2DCCA 3RVVA 1KXRA 1EWMA 3ERVA 1GCBA 1MEGA 1O0EA 1F29A 2JQFR 2VFBA 3K24A 3OVZA 3N3KA 1U5IA 2DZYA 1S4VA 2R9MA 1DF0A 1YALA 1NQCA 4XR7A 4GUZA 3GCBA 1AIMA 1NPZA 4W4UA 4WA6A 1FH0A 2OZ2A 3OF8A 2DJGB 3LTWA 2G8JA 2DJFB 1VSNA 4YVAA 4Q8HA 1F2AA 1YK7A 2B1NA 2AYOA 1ME3A 3U8EA 2VHSA 2PBHA 1CJLA 1KFXL 6PADA 2F1GA 4AXMA 2HD5A 4N79A 1CS8A 2DC9A 1PPPA 4C5PA 4QRGA 2OULA 2XU4A 4PP2E 4QRVA 4P6GA 3KWBX 2NQIA 3CH3X 1BY8A 4MSXA 2BDLA 4NV8A 4CDCB 2AUXA 2E00A 4AXLA 4YYWA 1CSBB 1CQDA 3PW3A 1U9VA 3HD3A 3MHHA 4NV7A 5FPWA 2FQ9A 4ZUXU 4QRXA 4YV8A 1GLOA 1HUCB 3E1ZB 3OISA 1PXVA 2F7DA 3PDFA 3KFQA 2HXZA 3RVWA 1ICFA 2ARYA 4FIPA 1KHPA 2E02A 1U9XA 3WXFA 4DMXA 3H6SA 1A6RA 2R9OA 2DZZA 3P5WA 4BS5A 3MHSA 1SNKA 3RVXA 3V6EA 2PADA 4PADA 4HWYA 3M99A 3BOWA 2PNSA 1MDWA 4P6EA 4FK5A 3ZUAA 4YYUA 5JA7A 3I06A 4CDEB 4PP1A 4KLBA 1X9YA 3IV2A 1M6DA 2E03A 3BCNA 4FJCA 7PCKA 1K3BB 1ATKA 2YJBA 4CDFB 2P0RA 3HHIA 3F5VA 2XU1A 3C9EA 4QBBA 1XKGA 3LFYA 4CDDB 1MIRA 2DCBA 1GX3A 3K9MA 3H8CA 1ZCMA 1PIPA 1MS6A 1F2CA 3P5XA 2DCDA 2DC8A 1BQIA 2H7JA 3CBJA 4DMYA 1NL6A 3KSEA 1QDQA 4X6HA 3O0UA 2G6DA 3TNXA 2AUZA 4K7CA 4YYQA 3OF9A 2R9CA 1MHWA 1CTEA 2CIOA 4N8WA 2Y6EA 3N3GA 1PE6A 1TLOA 1PCIA 3OVXA 1BGOA 3IHPA 1STFE 3AI8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3IEJ A;  1AYW A;  1YK8 A;  2E01 A;  1EWO A;  1Y08 A;  1EF7 A;  3KKU A;  2PRE A;  1ZIV A;  1U9Q X;  2P86 A;  5CHV A;  4YYV A;  4PI3 A;  4W5B A;  1U9W A;  1Y4H A;  1ITO A;  3PNR A;  2AS8 A;  4N4Z A;  5J94 A;  2GHU A;  2VHF A;  3NHE A;  2CB5 A;  4OEM A;  2FUD A;  3MOR A;  3CBK A;  2OP3 A;  8PCH A;  2AU1 A;  2XU3 A;  1Q6K A;  1IWD A;  3O1G A;  3CH2 X;  3KWZ A;  3QJ3 A;  4YYR A;  1AEC A;  2ATO A;  1PBH A;  5EF4 A;  2R9F A;  5EGW A;  4BSQ A;  2B1M A;  3IOQ A;  2G7Y A;  1MEM A;  3KW9 A;  4MZS A;  2P7U A;  3PBH A;  2DC6 A;  3BPM A;  4QH6 A;  1GMY A;  4I07 A;  1PAD A;  4Q8G A;  1AU4 A;  2AVW A;  5K16 A;  1YT7 A;  3WXE A;  3MTN A;  1CB5 A;  2AIM A;  3S3R A;  1PPO A;  1AU0 A;  5F02 A;  3N4C A;  4I05 A;  3IMA A;  3HWN A;  5JH3 A;  2WBF X;  4XUI A;  2YJ8 A;  3BC3 A;  2NQA A;  1THE A;  1POP A;  3H89 A;  2JQG R;  1PPD A;  5CHT A;  1VJV A;  3F75 A;  1BP4 A;  2DCA A;  3I3T A;  3B79 A;  1PPN A;  3K8U A;  4RY2 A;  5PAD A;  3WXG A;  3BPF A;  1KHQ A;  2BDZ A;  1NB5 A;  5CVO B;  2NQD B;  1AYV A;  1EWL A;  4W5C A;  3IUT A;  1KFU L;  1ME4 A;  5CVM A;  9PAP A;  4I04 A;  3KX1 A;  1TU6 A;  3BWK A;  4G54 A;  2HH5 A;  2C0Y A;  2FT2 A;  2YJC A;  4BPV A;  1SP4 B;  3LXS A;  4CZW A;  2FRQ A;  5CVN B;  1GEC E;  3V6C A;  4MZO A;  2IBI A;  1AYU A;  2YJ9 A;  3QT4 A;  2HHN A;  3QSD A;  3S3Q A;  2FO5 A;  1CV8 A;  2ACT A;  2NQG A;  2R6N A;  4X6I A;  1CPJ A;  1QOL A;  2Y5B A;  4YYS A;  3P5V A;  1CVZ A;  3D6S A;  4BQV A;  1QMY A;  3H8B A;  3DF0 A;  1F2B A;  3HHA A;  2AYN A;  2G8E A;  1AU3 A;  2FTD A;  2FRA A;  2YJ2 A;  3P5U A;  5A24 A;  2XU5 A;  4OEL A;  1AU2 A;  1NB3 A;  2IPP B;  4X6J A;  2FYE A;  1EWP A;  1NLJ A;  2GFO A;  2R9N A;  1JQP A;  3H7D A;  1DEU A;  1YVB A;  1TL9 A;  2DC7 A;  1QXP A;  4BS6 A;  2O6X A;  3USV A;  2DCC A;  3RVV A;  1KXR A;  1EWM A;  3ERV A;  1GCB A;  1MEG A;  1O0E A;  1F29 A;  2JQF R;  3K24 A;  3OVZ A;  3N3K A;  1U5I A;  2DZY A;  1S4V A;  2R9M A;  1DF0 A;  1YAL A;  1NQC A;  4XR7 A;  3GCB A;  1AIM A;  1NPZ A;  4W4U A;  4WA6 A;  1FH0 A;  2OZ2 A;  3OF8 A;  2DJG B;  2G8J A;  2DJF B;  1VSN A;  4YVA A;  4Q8H A;  1F2A A;  1YK7 A;  2B1N A;  2AYO A;  1ME3 A;  3U8E A;  2VHS A;  2PBH A;  1CJL A;  1KFX L;  6PAD A;  2F1G A;  4AXM A;  2HD5 A;  4N79 A;  1CS8 A;  2DC9 A;  1PPP A;  4QRG A;  2OUL A;  2XU4 A;  4PP2 E;  4QRV A;  4P6G A;  3KWB X;  2NQI A;  3CH3 X;  1BY8 A;  4MSX A;  2BDL A;  4CDC B;  2AUX A;  2E00 A;  4AXL A;  4YYW A;  1CSB B;  1CQD A;  3PW3 A;  1U9V A;  3HD3 A;  3MHH A;  5FPW A;  2FQ9 A;  4ZUX U;  4QRX A;  4YV8 A;  1GLO A;  1HUC B;  3E1Z B;  3OIS A;  1PXV A;  2F7D A;  3PDF A;  3KFQ A;  2HXZ A;  3RVW A;  1ICF A;  2ARY A;  4FIP A;  1KHP A;  2E02 A;  1U9X A;  3WXF A;  4DMX A;  3H6S A;  1A6R A;  2R9O A;  2DZZ A;  3P5W A;  4BS5 A;  3MHS A;  1SNK A;  3RVX A;  3V6E A;  2PAD A;  4PAD A;  4HWY A;  3M99 A;  3BOW A;  2PNS A;  1MDW A;  4P6E A;  4FK5 A;  3ZUA A;  4YYU A;  5JA7 A;  3I06 A;  4CDE B;  4PP1 A;  4KLB A;  1X9Y A;  3IV2 A;  1M6D A;  2E03 A;  3BCN A;  4FJC A;  7PCK A;  1K3B B;  1ATK A;  2YJB A;  4CDF B;  2P0R A;  3HHI A;  3F5V A;  2XU1 A;  3C9E A;  4QBB A;  1XKG A;  3LFY A;  4CDD B;  1MIR A;  2DCB A;  3K9M A;  3H8C A;  1ZCM A;  1PIP A;  1MS6 A;  1F2C A;  3P5X A;  2DCD A;  2DC8 A;  1BQI A;  2H7J A;  3CBJ A;  4DMY A;  1NL6 A;  3KSE A;  1QDQ A;  4X6H A;  3O0U A;  2G6D A;  3TNX A;  2AUZ A;  4K7C A;  4YYQ A;  3OF9 A;  2R9C A;  1MHW A;  1CTE A;  2CIO A;  4N8W A;  2Y6E A;  3N3G A;  1PE6 A;  1TLO A;  1PCI A;  3OVX A;  1BGO A;  3IHP A;  1STF E;  3AI8 A; 
#chains in the Genus database with same CATH topology
 3IEJ A;  1AYW A;  1YK8 A;  2E01 A;  1EWO A;  1Y08 A;  1EF7 A;  3KKU A;  2PRE A;  1ZIV A;  1U9Q X;  2P86 A;  4BOS A;  5CHV A;  4YYV A;  4PI3 A;  3PSE A;  1U9W A;  4W5B A;  1Y4H A;  1ITO A;  3PNR A;  2AS8 A;  4N4Z A;  5J94 A;  2GHU A;  4BOU A;  2VHF A;  3NHE A;  2CB5 A;  4OEM A;  2FUD A;  3MOR A;  3CBK A;  3MJ5 A;  2OP3 A;  8PCH A;  2AGA A;  2AU1 A;  2JRI A;  4RKX A;  2XU3 A;  1Q6K A;  1IWD A;  4XZX A;  3O1G A;  4OW0 A;  3CH2 X;  2J7Q C;  3KWZ A;  3QJ3 A;  4YYR A;  1AEC A;  2ATO A;  1PBH A;  5EF4 A;  2R9F A;  5EGW A;  4BSQ A;  2B1M A;  3IOQ A;  2G7Y A;  1MEM A;  3KW9 A;  4MZS A;  2P7U A;  3PBH A;  2DC6 A;  3BPM A;  4QH6 A;  1GMY A;  4I07 A;  1PAD A;  4Q8G A;  1AU4 A;  2AVW A;  2Z84 A;  5K16 A;  1YT7 A;  3WXE A;  3MTN A;  1CB5 A;  2AIM A;  3S3R A;  1PPO A;  1AU0 A;  4MM3 B;  5F02 A;  3N4C A;  4I05 A;  3IMA A;  3MTV A;  3HWN A;  5JH3 A;  2WBF X;  4XUI A;  2YJ8 A;  3BC3 A;  2NQA A;  1THE A;  4BOP A;  1POP A;  3H89 A;  2JQG R;  1PPD A;  5CHT A;  1VJV A;  3F75 A;  3BB7 A;  1BP4 A;  2DCA A;  3I3T A;  3B79 A;  4WUR A;  1PPN A;  4ZTB A;  5KO3 A;  3K8U A;  4RY2 A;  1PVJ A;  5PAD A;  3WXG A;  3BPF A;  1KHQ A;  2BDZ A;  1NB5 A;  5CVO B;  3MP2 A;  2NQD B;  1AYV A;  1EWL A;  4W5C A;  3IUT A;  1KFU L;  1ME4 A;  5CVM A;  9PAP A;  4I04 A;  3KX1 A;  1TU6 A;  3BWK A;  4G54 A;  2HH5 A;  2C0Y A;  2FT2 A;  2YJC A;  4BPV A;  1SP4 B;  3LXS A;  5EZS A;  3PHW A;  5E6J A;  4CZW A;  2FRQ A;  5CVN B;  1GEC E;  3V6C A;  4MZO A;  2IBI A;  1AYU A;  2YJ9 A;  3QT4 A;  2HHN A;  4REZ A;  3QSD A;  3S3Q A;  3OQC A;  2FO5 A;  1CV8 A;  2UZJ A;  2ACT A;  2NQG A;  4MI7 A;  2R6N A;  4X6I A;  1CPJ A;  1QOL A;  2Y5B A;  4YYS A;  3P5V A;  1CVZ A;  3BY4 A;  4BOQ A;  1YZB A;  3D6S A;  4BQV A;  1QMY A;  3H8B A;  3DF0 A;  1F2B A;  3HHA A;  2AYN A;  2G8E A;  1AU3 A;  2FTD A;  2FRA A;  2YJ2 A;  3P5U A;  5A24 A;  2XU5 A;  4OEL A;  1AU2 A;  1NB3 A;  2IPP B;  4X6J A;  2FYE A;  1EWP A;  3E9S A;  1NLJ A;  2GFO A;  2R9N A;  1JQP A;  3BBA A;  3H7D A;  4GUA A;  1DEU A;  1YVB A;  1TL9 A;  3PHX A;  2DC7 A;  1QXP A;  3TRK A;  2O6X A;  4BS6 A;  3USV A;  2FE8 A;  2DCC A;  3IFU A;  1KXR A;  3RVV A;  1EWM A;  3ERV A;  1GCB A;  1MEG A;  1O0E A;  1F29 A;  2JQF R;  3K24 A;  3OVZ A;  3N3K A;  1U5I A;  2DZY A;  1S4V A;  2R9M A;  1DF0 A;  1YAL A;  1NQC A;  3PRM A;  4XR7 A;  3GCB A;  1AIM A;  1NPZ A;  4PT5 A;  4W4U A;  4WA6 A;  4IP3 A;  2BU3 A;  1FH0 A;  2OZ2 A;  3OF8 A;  2DJG B;  2J7Q A;  2G8J A;  2DJF B;  1VSN A;  4YVA A;  4Q8H A;  1F2A A;  1YK7 A;  2B1N A;  2AYO A;  1ME3 A;  3U8E A;  2VHS A;  2PBH A;  1CJL A;  4D8B A;  1KFX L;  6PAD A;  2F1G A;  4AXM A;  2HD5 A;  4N79 A;  1CS8 A;  2DC9 A;  3PRP A;  1PPP A;  3W31 A;  4QRG A;  2OUL A;  2XU4 A;  2JTC A;  4PP2 E;  4QRV A;  4P6G A;  3KWB X;  2NQI A;  3CH3 X;  1BY8 A;  4MSX A;  2BDL A;  4RF1 A;  4CDC B;  2AUX A;  2E00 A;  3TMP A;  4AXL A;  4YYW A;  1CSB B;  1CQD A;  2BTW B;  3PW3 A;  1U9V A;  3HD3 A;  3MHH A;  5FPW A;  2FQ9 A;  2BTW A;  4ZUX U;  4QRX A;  4YV8 A;  1GLO A;  1HUC B;  3E1Z B;  3OIS A;  1PXV A;  4BOZ A;  1DKI A;  2F7D A;  3PDF A;  3KFQ A;  2HXZ A;  3RVW A;  1ICF A;  2ARY A;  4FIP A;  1KHP A;  2E02 A;  1U9X A;  3WXF A;  4DMX A;  3H6S A;  1A6R A;  2R9O A;  2DZZ A;  3P5W A;  1UKF A;  4BS5 A;  3MHS A;  1SNK A;  3RVX A;  3V6E A;  2PAD A;  4PAD A;  4HWY A;  3M99 A;  3BOW A;  2PNS A;  1MDW A;  4RNA A;  4P6E A;  4FK5 A;  4IUM A;  3ZUA A;  3PT2 A;  4YYU A;  5JA7 A;  3I06 A;  4CDE B;  4PP1 A;  3ZNH A;  4KLB A;  1X9Y A;  3IV2 A;  1M6D A;  2E03 A;  3BCN A;  4FJC A;  7PCK A;  1K3B B;  1ATK A;  2YJB A;  4CDF B;  2HWK A;  2P0R A;  3HHI A;  3F5V A;  2XU1 A;  4D8I A;  3C9E A;  3O65 A;  4QBB A;  1XKG A;  3LFY A;  4CDD B;  1MIR A;  2DOS A;  2DCB A;  5EZQ A;  4A5U A;  3K9M A;  3H8C A;  1ZCM A;  4OVZ B;  1PIP A;  1MS6 A;  1F2C A;  3P5X A;  5JZE A;  2DCD A;  3PHU A;  2DC8 A;  4D8E A;  1BQI A;  4P16 A;  2H7J A;  4OVZ A;  3CBJ A;  4DMY A;  4RF0 A;  1NL6 A;  3KSE A;  3B21 A;  1QDQ A;  3W30 A;  4X6H A;  3O0U A;  2G6D A;  3TNX A;  3C0R A;  2AUZ A;  4K7C A;  4M0W A;  4R3D A;  3RNV A;  4YYQ A;  3OF9 A;  2R9C A;  1MHW A;  1CTE A;  2CIO A;  4N8W A;  2Y6E A;  3N3G A;  1PE6 A;  1TLO A;  4HXD B;  1PCI A;  3OVX A;  1BGO A;  3IHP A;  1STF E;  3AI8 A; 
#chains in the Genus database with same CATH homology
 3IEJ A;  1AYW A;  1YK8 A;  2E01 A;  1EWO A;  1Y08 A;  1EF7 A;  3KKU A;  2PRE A;  1ZIV A;  1U9Q X;  3D9W A;  1E2T A;  2P86 A;  5CHV A;  4YYV A;  4PI3 A;  4W5B A;  1U9W A;  1Y4H A;  1ITO A;  4B55 A;  3PNR A;  2AS8 A;  4N4Z A;  5J94 A;  2GHU A;  2VHF A;  3NHE A;  2CB5 A;  4OEM A;  2FUD A;  3MOR A;  3CBK A;  2OP3 A;  1W6F A;  8PCH A;  2AU1 A;  2XU3 A;  1Q6K A;  1IWD A;  3O1G A;  3CH2 X;  3KWZ A;  3QJ3 A;  4YYR A;  1AEC A;  2ATO A;  1PBH A;  5EF4 A;  2R9F A;  5EGW A;  4BSQ A;  2B1M A;  3IOQ A;  2G7Y A;  1MEM A;  3KW9 A;  4MZS A;  2P7U A;  3PBH A;  2DC6 A;  3BPM A;  4QH6 A;  1GMY A;  4I07 A;  1PAD A;  4Q8G A;  1AU4 A;  1W5R A;  2AVW A;  5K16 A;  1YT7 A;  3WXE A;  3MTN A;  1CB5 A;  2AIM A;  3S3R A;  1PPO A;  1AU0 A;  5F02 A;  3N4C A;  4I05 A;  3IMA A;  3HWN A;  5JH3 A;  2WBF X;  4XUI A;  2YJ8 A;  3BC3 A;  2NQA A;  1THE A;  1POP A;  3H89 A;  2JQG R;  1PPD A;  5CHT A;  1VJV A;  3F75 A;  1BP4 A;  2DCA A;  3I3T A;  3B79 A;  1PPN A;  3K8U A;  4RY2 A;  5PAD A;  3WXG A;  3BPF A;  1KHQ A;  2BDZ A;  1NB5 A;  5CVO B;  2NQD B;  1AYV A;  1EWL A;  4W5C A;  3IUT A;  1KFU L;  1ME4 A;  5CVM A;  9PAP A;  4I04 A;  2BSZ A;  3KX1 A;  1TU6 A;  3BWK A;  4G54 A;  2HH5 A;  2C0Y A;  2FT2 A;  2YJC A;  4BPV A;  1SP4 B;  3LXS A;  4CZW A;  2FRQ A;  5CVN B;  1GEC E;  3V6C A;  4MZO A;  2IBI A;  1AYU A;  2VFC A;  2YJ9 A;  3QT4 A;  2HHN A;  1W4T A;  3QSD A;  3S3Q A;  2FO5 A;  1CV8 A;  2ACT A;  2NQG A;  2R6N A;  4X6I A;  1CPJ A;  1QOL A;  2Y5B A;  4YYS A;  3P5V A;  1CVZ A;  3D6S A;  4BQV A;  1QMY A;  3H8B A;  3DF0 A;  1F2B A;  3HHA A;  2AYN A;  2G8E A;  4BGF A;  1AU3 A;  2FTD A;  2FRA A;  2YJ2 A;  3P5U A;  5A24 A;  2XU5 A;  4OEL A;  1AU2 A;  1NB3 A;  2IPP B;  4X6J A;  2FYE A;  1EWP A;  1NLJ A;  2GFO A;  2R9N A;  1JQP A;  3H7D A;  1DEU A;  1YVB A;  1TL9 A;  2DC7 A;  1QXP A;  4BS6 A;  2O6X A;  3USV A;  2DCC A;  3RVV A;  1KXR A;  1EWM A;  3ERV A;  1GCB A;  1MEG A;  1O0E A;  1F29 A;  2JQF R;  2VFB A;  3K24 A;  3OVZ A;  3N3K A;  1U5I A;  2DZY A;  1S4V A;  2R9M A;  1DF0 A;  1YAL A;  1NQC A;  4XR7 A;  4GUZ A;  3GCB A;  1AIM A;  1NPZ A;  4W4U A;  4WA6 A;  1FH0 A;  2OZ2 A;  3OF8 A;  2DJG B;  3LTW A;  2G8J A;  2DJF B;  1VSN A;  4YVA A;  4Q8H A;  1F2A A;  1YK7 A;  2B1N A;  2AYO A;  1ME3 A;  3U8E A;  2VHS A;  2PBH A;  1CJL A;  1KFX L;  6PAD A;  2F1G A;  4AXM A;  2HD5 A;  4N79 A;  1CS8 A;  2DC9 A;  1PPP A;  4C5P A;  4QRG A;  2OUL A;  2XU4 A;  4PP2 E;  4QRV A;  4P6G A;  3KWB X;  2NQI A;  3CH3 X;  1BY8 A;  4MSX A;  2BDL A;  4NV8 A;  4CDC B;  2AUX A;  2E00 A;  4AXL A;  4YYW A;  1CSB B;  1CQD A;  3PW3 A;  1U9V A;  3HD3 A;  3MHH A;  4NV7 A;  5FPW A;  2FQ9 A;  4ZUX U;  4QRX A;  4YV8 A;  1GLO A;  1HUC B;  3E1Z B;  3OIS A;  1PXV A;  2F7D A;  3PDF A;  3KFQ A;  2HXZ A;  3RVW A;  1ICF A;  2ARY A;  4FIP A;  1KHP A;  2E02 A;  1U9X A;  3WXF A;  4DMX A;  3H6S A;  1A6R A;  2R9O A;  2DZZ A;  3P5W A;  4BS5 A;  3MHS A;  1SNK A;  3RVX A;  3V6E A;  2PAD A;  4PAD A;  4HWY A;  3M99 A;  3BOW A;  2PNS A;  1MDW A;  4P6E A;  4FK5 A;  3ZUA A;  4YYU A;  5JA7 A;  3I06 A;  4CDE B;  4PP1 A;  4KLB A;  1X9Y A;  3IV2 A;  1M6D A;  2E03 A;  3BCN A;  4FJC A;  7PCK A;  1K3B B;  1ATK A;  2YJB A;  4CDF B;  2P0R A;  3HHI A;  3F5V A;  2XU1 A;  3C9E A;  4QBB A;  1XKG A;  3LFY A;  4CDD B;  1MIR A;  2DCB A;  1GX3 A;  3K9M A;  3H8C A;  1ZCM A;  1PIP A;  1MS6 A;  1F2C A;  3P5X A;  2DCD A;  2DC8 A;  1BQI A;  2H7J A;  3CBJ A;  4DMY A;  1NL6 A;  3KSE A;  1QDQ A;  4X6H A;  3O0U A;  2G6D A;  3TNX A;  2AUZ A;  4K7C A;  4YYQ A;  3OF9 A;  2R9C A;  1MHW A;  1CTE A;  2CIO A;  4N8W A;  2Y6E A;  3N3G A;  1PE6 A;  1TLO A;  1PCI A;  3OVX A;  1BGO A;  3IHP A;  1STF E;  3AI8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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