4HWYA

Trypanosoma brucei procathepsin b solved from 40 fs free-electron laser pulse data by serial femtosecond x-ray crystallography
Total Genus 98
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
98
sequence length
314
structure length
308
Chain Sequence
EDAPVLSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKRLNGVIKILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQIADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLLACCSDCGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHCSHHSKSKNGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSWTSYALQGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYHHVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDGYFLIRRGSSECGIEDGGSAGIPLAPNTA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser.
pubmed doi rcsb
molecule tags Hydrolase
source organism Trypanosoma brucei brucei treu927
molecule keywords Cysteine peptidase C (CPC)
total genus 98
structure length 308
sequence length 314
ec nomenclature ec 3.4.22.-:
pdb deposition date 2012-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00112 Peptidase_C1 Papain family cysteine protease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.70.10 Alpha Beta Alpha-Beta Complex Cathepsin B; Chain A Cysteine proteinases 4hwyA00
1F29A 2AVWA 1POPA 3H8CA 3WXFA 1EF7A 1A6RA 1CSBB 2DCDA 3BOWA 3IHPA 2PBHA 1EWLA 3CBKA 2DC6A 3IUTA 1GMYA 3CH3X 5CVNB 2FRAA 4FK5A 3DF0A 4QBBA 1TL9A 3BPMA 4MZSA 2ATOA 5CVMA 3P5XA 4X6IA 2FUDA 3OISA 2GFOA 3P5WA 1VJVA 7PCKA 1AYUA 2H7JA 4AXLA 1CQDA 2AYNA 3MORA 1EWPA 3V6EA 2E01A 3WXGA 1AECA 2JQFR 3LXSA 4CZWA 1IWDA 2DC9A 4CDFB 2WBFX 5CHVA 3PW3A 3S3QA 2DC8A 1PBHA 1NPZA 1Q6KA 1Y08A 4YYUA 1U9WA 1QDQA 3O1GA 2CB5A 2DJFB 1ATKA 5EGWA 2E02A 2R9FA 8PCHA 3QT4A 4FIPA 2R9OA 2FQ9A 3AI8A 1CJLA 3KFQA 1NQCA 4PI3A 1PCIA 3K24A 5K16A 4DMXA 1PE6A 4BS5A 1VSNA 2VHFA 3GCBA 3KKUA 3KWZA 4CDDB 3V6CA 4Q8HA 3IV2A 2YJBA 4Q8GA 2Y5BA 3CH2X 4CDEB 1BY8A 2R9NA 3RVXA 5PADA 3KW9A 1CTEA 2AYOA 1CS8A 1BQIA 2BDLA 4KLBA 4MSXA 1TU6A 2XU3A 4I04A 2GHUA 6PADA 4FJCA 1AIMA 1YT7A 4P6EA 1PXVA 3O0UA 2E00A 9PAPA 3KWBX 1STFE 3BC3A 2G8JA 2G7YA 2FRQA 1F2AA 3I3TA 2P86A 2DCBA 2DZZA 2YJ9A 2ACTA 4BPVA 3OVZA 2ARYA 4WA6A 1KHPA 4W5CA 2FTDA 3N3KA 4N8WA 1YVBA 3RVWA 4QRXA 1ME3A 4YYWA 3H89A 4OELA 5A24A 1MDWA 4MZOA 1CVZA 3IOQA 1MEMA 3I06A 3K8UA 4BQVA 2IPPB 3P5UA 4BSQA 4DMYA 5CHTA 3D6SA 2OP3A 1PPNA 4YV8A 1GCBA 2HXZA 4N4ZA 2PREA 2DCCA 1NB5A 2YJ2A 1SP4B 2AIMA 3KX1A 4W5BA 2FT2A 4PADA 2DC7A 4QH6A 4QRVA 2Y6EA 1KXRA 1MEGA 2PADA 4I05A 1QXPA 2YJCA 3IMAA 1PPPA 4QRGA 1GLOA 3HD3A 2BDZA 4G54A 1MHWA 1NLJA 4CDCB 4X6HA 3E1ZB 5JA7A 4P6GA 3N4CA 4YYSA 1THEA 2CIOA 3K9MA 3H6SA 1F2CA 3H8BA 3S3RA 1CV8A 2PNSA 4HWYA 1XKGA 5JH3A 3F5VA 3WXEA 2AU1A 1ITOA 1AU0A 3IEJA 2HH5A 1AYWA 1CB5A 3QJ3A 1KFUL 2NQIA 2HHNA 1PPOA 2JQGR 1KHQA 1Y4HA 3BWKA 2XU4A 3MHSA 1AU3A 3RVVA 1QMYA 1FH0A 2AUZA 3ERVA 3HHAA 2OZ2A 3HHIA 2DZYA 1U9VA 4YYVA 2FYEA 2HD5A 4XUIA 1AU2A 3KSEA 1PPDA 4XR7A 2NQDB 3MHHA 4W4UA 3PBHA 5CVOB 2R9MA 4RY2A 1PIPA 1U9QX 5EF4A 1QOLA 2B1NA 3LFYA 1PADA 2VHSA 3PNRA 1ME4A 1K3BB 4N79A 1BP4A 1JQPA 1EWOA 1CPJA 2NQAA 1MS6A 4YYQA 1YK7A 2YJ8A 3M99A 1DF0A 1EWMA 2XU1A 2AS8A 3HWNA 1YK8A 1X9YA 1M6DA 2G8EA 2FO5A 3U8EA 2IBIA 3ZUAA 2P0RA 2C0YA 5J94A 1NL6A 2E03A 4AXMA 4K7CA 1DEUA 2R6NA 3USVA 4YYRA 2F7DA 3MTNA 4OEMA 1MIRA 3TNXA 1NB3A 3N3GA 2DCAA 2XU5A 3CBJA 5F02A 4ZUXU 2P7UA 2B1MA 2OULA 3P5VA 1GECE 1BGOA 1HUCB 1F2BA 1SNKA 1S4VA 3C9EA 1O0EA 2NQGA 5FPWA 4YVAA 2DJGB 1U9XA 2G6DA 2R9CA 3F75A 3PDFA 4PP1A 3BPFA 3NHEA 1AYVA 1TLOA 3OVXA 1AU4A 1YALA 3B79A 3BCNA 4I07A 3OF9A 2AUXA 4X6JA 2F1GA 3QSDA 1ICFA 3H7DA 1KFXL 3OF8A 4BS6A 1ZIVA 1ZCMA 1U5IA 2O6XA 4PP2E
chains in the Genus database with same CATH superfamily
1F29A 2AVWA 1POPA 3H8CA 3WXFA 4D8IA 2J7QA 1EF7A 1A6RA 3MTVA 1CSBB 4OVZA 2DCDA 3BOWA 3IHPA 3BBAA 2PBHA 4RF1A 1EWLA 3RNVA 3CBKA 2DC6A 3IUTA 1GMYA 3CH3X 3PRMA 5CVNB 2FRAA 5EZQA 2FE8A 4FK5A 3DF0A 4QBBA 1TL9A 3BPMA 4MZSA 2ATOA 5CVMA 3P5XA 4X6IA 2FUDA 3OISA 3TRKA 2GFOA 3P5WA 1VJVA 7PCKA 3MJ5A 4IP3A 1AYUA 2H7JA 4AXLA 1CQDA 2AYNA 3MORA 1EWPA 3V6EA 2E01A 3WXGA 1AECA 2JQFR 3LXSA 2AGAA 4CZWA 1IWDA 2DC9A 4CDFB 2WBFX 5CHVA 3PW3A 3S3QA 2DC8A 4D8EA 1PBHA 1NPZA 1Q6KA 1Y08A 4YYUA 1U9WA 1QDQA 3O1GA 2CB5A 2DJFB 1ATKA 5EGWA 2E02A 2R9FA 8PCHA 3QT4A 4FIPA 2R9OA 2FQ9A 3AI8A 4MI7A 1CJLA 3KFQA 1NQCA 4M0WA 4PI3A 1PCIA 3K24A 1DKIA 5K16A 4DMXA 1PE6A 4BS5A 3ZNHA 1VSNA 2VHFA 3GCBA 4R3DA 3KKUA 3KWZA 4CDDB 3V6CA 3PHWA 2J7QC 4Q8HA 3IV2A 2YJBA 4Q8GA 3PT2A 2Y5BA 3CH2X 4CDEB 2DOSA 1BY8A 2R9NA 3RVXA 5PADA 3KW9A 1CTEA 2AYOA 1CS8A 1BQIA 2BDLA 4KLBA 4MSXA 1TU6A 2XU3A 4I04A 2GHUA 6PADA 4FJCA 1AIMA 2JTCA 1YT7A 4P6EA 1PXVA 3BB7A 3O0UA 2E00A 9PAPA 3KWBX 1STFE 3BC3A 2G8JA 2G7YA 3PHXA 2FRQA 1F2AA 3I3TA 2P86A 2DCBA 2DZZA 2YJ9A 2ACTA 4BPVA 2BTWA 4XZXA 3OVZA 2ARYA 3B21A 4WA6A 1KHPA 4W5CA 4PT5A 2FTDA 3N3KA 4N8WA 1YVBA 3RVWA 4QRXA 1ME3A 4YYWA 3H89A 4OELA 5A24A 3PSEA 1MDWA 4MZOA 4ZTBA 3W30A 1CVZA 3IOQA 4HXDB 1MEMA 3I06A 3K8UA 4BQVA 2IPPB 3P5UA 4WURA 4BSQA 4DMYA 5CHTA 3D6SA 3PHUA 2OP3A 1PPNA 4YV8A 1GCBA 3BY4A 2HXZA 4N4ZA 2PREA 4REZA 2DCCA 1NB5A 2YJ2A 1SP4B 2AIMA 3KX1A 4W5BA 2FT2A 4PADA 2DC7A 4OVZB 4QH6A 4QRVA 2Y6EA 3IFUA 1KXRA 1MEGA 2PADA 3MP2A 4I05A 1QXPA 2UZJA 2YJCA 5KO3A 3IMAA 1PPPA 4BOZA 4QRGA 1GLOA 3HD3A 2BDZA 4G54A 1MHWA 1NLJA 4CDCB 4X6HA 3E1ZB 5JA7A 4P6GA 3N4CA 4YYSA 4IUMA 1THEA 2CIOA 3K9MA 3H6SA 1F2CA 3H8BA 2BU3A 3S3RA 1CV8A 2PNSA 4HWYA 1XKGA 4BOPA 5JH3A 3F5VA 3WXEA 2AU1A 1ITOA 1AU0A 3TMPA 3IEJA 2HH5A 1AYWA 1CB5A 3QJ3A 1KFUL 2NQIA 2HHNA 1PPOA 2JQGR 1KHQA 1Y4HA 3BWKA 2XU4A 3MHSA 1AU3A 4BOSA 3RVVA 4P16A 1QMYA 1FH0A 2AUZA 3ERVA 3HHAA 4RF0A 2OZ2A 3HHIA 2DZYA 1U9VA 4MM3B 4YYVA 2FYEA 2HD5A 1YZBA 4XUIA 1AU2A 3KSEA 1PPDA 4XR7A 2NQDB 3MHHA 3W31A 1PVJA 4W4UA 3PBHA 5CVOB 2R9MA 4RY2A 1PIPA 1U9QX 5EF4A 1QOLA 2B1NA 3LFYA 1PADA 2VHSA 3PNRA 5E6JA 1ME4A 3E9SA 1K3BB 4N79A 1BP4A 1JQPA 4RKXA 1EWOA 1CPJA 2NQAA 1MS6A 4YYQA 1YK7A 2YJ8A 3M99A 1DF0A 3O65A 1EWMA 2XU1A 2AS8A 3HWNA 1YK8A 4D8BA 1X9YA 1M6DA 2G8EA 2FO5A 5EZSA 1UKFA 2IBIA 3U8EA 3ZUAA 2P0RA 2C0YA 5J94A 4A5UA 1NL6A 2E03A 4AXMA 4K7CA 5JZEA 1DEUA 3C0RA 2R6NA 3USVA 4OW0A 4YYRA 2F7DA 3MTNA 4OEMA 1MIRA 3TNXA 1NB3A 3N3GA 2BTWB 2DCAA 2XU5A 3OQCA 3CBJA 2JRIA 5F02A 4ZUXU 2P7UA 2B1MA 2OULA 3P5VA 1GECE 1BGOA 1HUCB 1F2BA 1SNKA 1S4VA 4BOQA 4GUAA 3C9EA 1O0EA 2NQGA 5FPWA 4BOUA 4YVAA 2DJGB 1U9XA 2G6DA 2R9CA 3F75A 3PDFA 4PP1A 3BPFA 3NHEA 1AYVA 1TLOA 3OVXA 4RNAA 1AU4A 1YALA 3B79A 3BCNA 2HWKA 4I07A 3OF9A 2AUXA 4X6JA 2F1GA 3QSDA 1ICFA 3H7DA 1KFXL 3OF8A 4BS6A 1ZIVA 1ZCMA 1U5IA 2Z84A 3PRPA 2O6XA 4PP2E
chains in the Genus database with same CATH topology
1F29A 2AVWA 1POPA 3H8CA 3WXFA 1EF7A 1A6RA 1CSBB 2DCDA 3BOWA 3IHPA 2PBHA 1EWLA 3CBKA 2DC6A 3IUTA 1GMYA 3CH3X 5CVNB 2FRAA 3D9WA 4FK5A 3DF0A 4QBBA 1TL9A 3BPMA 4MZSA 2ATOA 5CVMA 3P5XA 4X6IA 2FUDA 3OISA 2GFOA 3P5WA 1VJVA 7PCKA 1AYUA 2H7JA 4AXLA 1CQDA 2AYNA 3MORA 1EWPA 3V6EA 2E01A 3WXGA 1AECA 2JQFR 3LXSA 4CZWA 1IWDA 2DC9A 4CDFB 2WBFX 5CHVA 3PW3A 3S3QA 2DC8A 1PBHA 1NPZA 1Q6KA 1Y08A 4YYUA 1U9WA 1QDQA 3O1GA 2CB5A 2DJFB 1ATKA 5EGWA 2E02A 2R9FA 8PCHA 3QT4A 4FIPA 2R9OA 2FQ9A 3AI8A 1CJLA 3KFQA 1NQCA 4PI3A 1PCIA 3K24A 5K16A 4DMXA 1PE6A 4BS5A 1W5RA 1VSNA 2VHFA 3GCBA 3KKUA 3KWZA 4CDDB 3V6CA 4Q8HA 3IV2A 2YJBA 4Q8GA 2Y5BA 3CH2X 4CDEB 1BY8A 2R9NA 3RVXA 5PADA 3KW9A 1CTEA 2AYOA 1CS8A 1BQIA 2BDLA 4KLBA 4MSXA 1TU6A 2XU3A 4I04A 2GHUA 6PADA 4FJCA 1AIMA 1YT7A 1W6FA 4P6EA 1PXVA 3O0UA 2E00A 9PAPA 3KWBX 1STFE 3BC3A 2G8JA 2G7YA 2FRQA 1F2AA 3I3TA 2P86A 2DCBA 2DZZA 2YJ9A 2ACTA 4BPVA 3OVZA 2ARYA 4WA6A 4B55A 1KHPA 4W5CA 2FTDA 4NV8A 3N3KA 4N8WA 1YVBA 3RVWA 4QRXA 1ME3A 4YYWA 3H89A 4OELA 5A24A 1MDWA 4MZOA 1CVZA 3IOQA 1MEMA 3I06A 3K8UA 4BQVA 2IPPB 3P5UA 4BSQA 4DMYA 5CHTA 2VFBA 3D6SA 2OP3A 1PPNA 4YV8A 1GCBA 2HXZA 4N4ZA 2PREA 2DCCA 1NB5A 2YJ2A 1SP4B 2AIMA 3KX1A 4W5BA 2FT2A 4PADA 2DC7A 4QH6A 4QRVA 2Y6EA 4NV7A 1KXRA 1MEGA 2PADA 4I05A 1QXPA 2YJCA 3IMAA 1PPPA 4QRGA 1GLOA 3HD3A 2BDZA 4G54A 1MHWA 1NLJA 4CDCB 4X6HA 3E1ZB 5JA7A 4P6GA 3N4CA 4YYSA 1THEA 2CIOA 3K9MA 3H6SA 1F2CA 3H8BA 3S3RA 1CV8A 2PNSA 4HWYA 1XKGA 5JH3A 3F5VA 3WXEA 2AU1A 1ITOA 1AU0A 1E2TA 3IEJA 2HH5A 1AYWA 1CB5A 3QJ3A 1KFUL 2NQIA 2HHNA 1PPOA 2JQGR 1KHQA 1Y4HA 3BWKA 2XU4A 3MHSA 1AU3A 3RVVA 1QMYA 1FH0A 2AUZA 3ERVA 3HHAA 2OZ2A 3HHIA 2DZYA 1U9VA 4YYVA 2FYEA 2HD5A 1GX3A 4XUIA 1AU2A 3KSEA 1PPDA 4XR7A 2NQDB 3MHHA 2BSZA 4W4UA 3PBHA 5CVOB 2R9MA 4RY2A 1PIPA 1U9QX 5EF4A 1QOLA 2B1NA 3LFYA 1PADA 2VHSA 3PNRA 1ME4A 4GUZA 1K3BB 4N79A 1BP4A 1JQPA 1EWOA 1CPJA 2NQAA 1MS6A 4YYQA 1YK7A 2YJ8A 3M99A 1DF0A 1EWMA 2XU1A 2AS8A 3HWNA 1YK8A 1X9YA 1M6DA 2G8EA 2FO5A 3U8EA 2IBIA 3ZUAA 2P0RA 2C0YA 5J94A 1NL6A 2E03A 3LTWA 4AXMA 4K7CA 1DEUA 2R6NA 3USVA 4BGFA 4YYRA 2VFCA 2F7DA 3MTNA 4OEMA 1MIRA 3TNXA 1NB3A 3N3GA 2DCAA 2XU5A 3CBJA 5F02A 4ZUXU 2P7UA 2B1MA 2OULA 3P5VA 1GECE 1BGOA 1HUCB 1F2BA 1SNKA 1S4VA 3C9EA 1O0EA 2NQGA 5FPWA 4YVAA 2DJGB 1U9XA 2G6DA 2R9CA 3F75A 3PDFA 4PP1A 3BPFA 3NHEA 1AYVA 1TLOA 1W4TA 3OVXA 4C5PA 1AU4A 1YALA 3B79A 3BCNA 4I07A 3OF9A 2AUXA 4X6JA 2F1GA 3QSDA 1ICFA 3H7DA 1KFXL 3OF8A 4BS6A 1ZIVA 1ZCMA 1U5IA 2O6XA 4PP2E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1F29 A;  2AVW A;  1POP A;  3H8C A;  3WXF A;  1EF7 A;  1A6R A;  1CSB B;  2DCD A;  3BOW A;  3IHP A;  2PBH A;  1EWL A;  3CBK A;  2DC6 A;  3IUT A;  1GMY A;  3CH3 X;  5CVN B;  2FRA A;  4FK5 A;  3DF0 A;  4QBB A;  1TL9 A;  3BPM A;  4MZS A;  2ATO A;  5CVM A;  3P5X A;  4X6I A;  2FUD A;  3OIS A;  2GFO A;  3P5W A;  1VJV A;  7PCK A;  1AYU A;  2H7J A;  4AXL A;  1CQD A;  2AYN A;  3MOR A;  1EWP A;  3V6E A;  2E01 A;  3WXG A;  1AEC A;  2JQF R;  3LXS A;  4CZW A;  1IWD A;  2DC9 A;  4CDF B;  2WBF X;  5CHV A;  3PW3 A;  3S3Q A;  2DC8 A;  1PBH A;  1NPZ A;  1Q6K A;  1Y08 A;  4YYU A;  1U9W A;  1QDQ A;  3O1G A;  2CB5 A;  2DJF B;  1ATK A;  5EGW A;  2E02 A;  2R9F A;  8PCH A;  3QT4 A;  4FIP A;  2R9O A;  2FQ9 A;  3AI8 A;  1CJL A;  3KFQ A;  1NQC A;  4PI3 A;  1PCI A;  3K24 A;  5K16 A;  4DMX A;  1PE6 A;  4BS5 A;  1VSN A;  2VHF A;  3GCB A;  3KKU A;  3KWZ A;  4CDD B;  3V6C A;  4Q8H A;  3IV2 A;  2YJB A;  4Q8G A;  2Y5B A;  3CH2 X;  4CDE B;  1BY8 A;  2R9N A;  3RVX A;  5PAD A;  3KW9 A;  1CTE A;  2AYO A;  1CS8 A;  1BQI A;  2BDL A;  4KLB A;  4MSX A;  1TU6 A;  2XU3 A;  4I04 A;  2GHU A;  6PAD A;  4FJC A;  1AIM A;  1YT7 A;  4P6E A;  1PXV A;  3O0U A;  2E00 A;  9PAP A;  3KWB X;  1STF E;  3BC3 A;  2G8J A;  2G7Y A;  2FRQ A;  1F2A A;  3I3T A;  2P86 A;  2DCB A;  2DZZ A;  2YJ9 A;  2ACT A;  4BPV A;  3OVZ A;  2ARY A;  4WA6 A;  1KHP A;  4W5C A;  2FTD A;  3N3K A;  4N8W A;  1YVB A;  3RVW A;  4QRX A;  1ME3 A;  4YYW A;  3H89 A;  4OEL A;  5A24 A;  1MDW A;  4MZO A;  1CVZ A;  3IOQ A;  1MEM A;  3I06 A;  3K8U A;  4BQV A;  2IPP B;  3P5U A;  4BSQ A;  4DMY A;  5CHT A;  3D6S A;  2OP3 A;  1PPN A;  4YV8 A;  1GCB A;  2HXZ A;  4N4Z A;  2PRE A;  2DCC A;  1NB5 A;  2YJ2 A;  1SP4 B;  2AIM A;  3KX1 A;  4W5B A;  2FT2 A;  4PAD A;  2DC7 A;  4QH6 A;  4QRV A;  2Y6E A;  1KXR A;  1MEG A;  2PAD A;  4I05 A;  1QXP A;  2YJC A;  3IMA A;  1PPP A;  4QRG A;  1GLO A;  3HD3 A;  2BDZ A;  4G54 A;  1MHW A;  1NLJ A;  4CDC B;  4X6H A;  3E1Z B;  5JA7 A;  4P6G A;  3N4C A;  4YYS A;  1THE A;  2CIO A;  3K9M A;  3H6S A;  1F2C A;  3H8B A;  3S3R A;  1CV8 A;  2PNS A;  4HWY A;  1XKG A;  5JH3 A;  3F5V A;  3WXE A;  2AU1 A;  1ITO A;  1AU0 A;  3IEJ A;  2HH5 A;  1AYW A;  1CB5 A;  3QJ3 A;  1KFU L;  2NQI A;  2HHN A;  1PPO A;  2JQG R;  1KHQ A;  1Y4H A;  3BWK A;  2XU4 A;  3MHS A;  1AU3 A;  3RVV A;  1QMY A;  1FH0 A;  2AUZ A;  3ERV A;  3HHA A;  2OZ2 A;  3HHI A;  2DZY A;  1U9V A;  4YYV A;  2FYE A;  2HD5 A;  4XUI A;  1AU2 A;  3KSE A;  1PPD A;  4XR7 A;  2NQD B;  3MHH A;  4W4U A;  3PBH A;  5CVO B;  2R9M A;  4RY2 A;  1PIP A;  1U9Q X;  5EF4 A;  1QOL A;  2B1N A;  3LFY A;  1PAD A;  2VHS A;  3PNR A;  1ME4 A;  1K3B B;  4N79 A;  1BP4 A;  1JQP A;  1EWO A;  1CPJ A;  2NQA A;  1MS6 A;  4YYQ A;  1YK7 A;  2YJ8 A;  3M99 A;  1DF0 A;  1EWM A;  2XU1 A;  2AS8 A;  3HWN A;  1YK8 A;  1X9Y A;  1M6D A;  2G8E A;  2FO5 A;  3U8E A;  2IBI A;  3ZUA A;  2P0R A;  2C0Y A;  5J94 A;  1NL6 A;  2E03 A;  4AXM A;  4K7C A;  1DEU A;  2R6N A;  3USV A;  4YYR A;  2F7D A;  3MTN A;  4OEM A;  1MIR A;  3TNX A;  1NB3 A;  3N3G A;  2DCA A;  2XU5 A;  3CBJ A;  5F02 A;  4ZUX U;  2P7U A;  2B1M A;  2OUL A;  3P5V A;  1GEC E;  1BGO A;  1HUC B;  1F2B A;  1SNK A;  1S4V A;  3C9E A;  1O0E A;  2NQG A;  5FPW A;  4YVA A;  2DJG B;  1U9X A;  2G6D A;  2R9C A;  3F75 A;  3PDF A;  4PP1 A;  3BPF A;  3NHE A;  1AYV A;  1TLO A;  3OVX A;  1AU4 A;  1YAL A;  3B79 A;  3BCN A;  4I07 A;  3OF9 A;  2AUX A;  4X6J A;  2F1G A;  3QSD A;  1ICF A;  3H7D A;  1KFX L;  3OF8 A;  4BS6 A;  1ZIV A;  1ZCM A;  1U5I A;  2O6X A;  4PP2 E; 
#chains in the Genus database with same CATH topology
 1F29 A;  2AVW A;  1POP A;  3H8C A;  3WXF A;  4D8I A;  2J7Q A;  1EF7 A;  1A6R A;  3MTV A;  1CSB B;  4OVZ A;  2DCD A;  3BOW A;  3IHP A;  3BBA A;  2PBH A;  4RF1 A;  1EWL A;  3RNV A;  3CBK A;  2DC6 A;  3IUT A;  1GMY A;  3CH3 X;  3PRM A;  5CVN B;  2FRA A;  5EZQ A;  2FE8 A;  4FK5 A;  3DF0 A;  4QBB A;  1TL9 A;  3BPM A;  4MZS A;  2ATO A;  5CVM A;  3P5X A;  4X6I A;  2FUD A;  3OIS A;  3TRK A;  2GFO A;  3P5W A;  1VJV A;  7PCK A;  3MJ5 A;  4IP3 A;  1AYU A;  2H7J A;  4AXL A;  1CQD A;  2AYN A;  3MOR A;  1EWP A;  3V6E A;  2E01 A;  3WXG A;  1AEC A;  2JQF R;  3LXS A;  2AGA A;  4CZW A;  1IWD A;  2DC9 A;  4CDF B;  2WBF X;  5CHV A;  3PW3 A;  3S3Q A;  2DC8 A;  4D8E A;  1PBH A;  1NPZ A;  1Q6K A;  1Y08 A;  4YYU A;  1U9W A;  1QDQ A;  3O1G A;  2CB5 A;  2DJF B;  1ATK A;  5EGW A;  2E02 A;  2R9F A;  8PCH A;  3QT4 A;  4FIP A;  2R9O A;  2FQ9 A;  3AI8 A;  4MI7 A;  1CJL A;  3KFQ A;  1NQC A;  4M0W A;  4PI3 A;  1PCI A;  3K24 A;  1DKI A;  5K16 A;  4DMX A;  1PE6 A;  4BS5 A;  3ZNH A;  1VSN A;  2VHF A;  3GCB A;  4R3D A;  3KKU A;  3KWZ A;  4CDD B;  3V6C A;  3PHW A;  2J7Q C;  4Q8H A;  3IV2 A;  2YJB A;  4Q8G A;  3PT2 A;  2Y5B A;  3CH2 X;  4CDE B;  2DOS A;  1BY8 A;  2R9N A;  3RVX A;  5PAD A;  3KW9 A;  1CTE A;  2AYO A;  1CS8 A;  1BQI A;  2BDL A;  4KLB A;  4MSX A;  1TU6 A;  2XU3 A;  4I04 A;  2GHU A;  6PAD A;  4FJC A;  1AIM A;  2JTC A;  1YT7 A;  4P6E A;  1PXV A;  3BB7 A;  3O0U A;  2E00 A;  9PAP A;  3KWB X;  1STF E;  3BC3 A;  2G8J A;  2G7Y A;  3PHX A;  2FRQ A;  1F2A A;  3I3T A;  2P86 A;  2DCB A;  2DZZ A;  2YJ9 A;  2ACT A;  4BPV A;  2BTW A;  4XZX A;  3OVZ A;  2ARY A;  3B21 A;  4WA6 A;  1KHP A;  4W5C A;  4PT5 A;  2FTD A;  3N3K A;  4N8W A;  1YVB A;  3RVW A;  4QRX A;  1ME3 A;  4YYW A;  3H89 A;  4OEL A;  5A24 A;  3PSE A;  1MDW A;  4MZO A;  4ZTB A;  3W30 A;  1CVZ A;  3IOQ A;  4HXD B;  1MEM A;  3I06 A;  3K8U A;  4BQV A;  2IPP B;  3P5U A;  4WUR A;  4BSQ A;  4DMY A;  5CHT A;  3D6S A;  3PHU A;  2OP3 A;  1PPN A;  4YV8 A;  1GCB A;  3BY4 A;  2HXZ A;  4N4Z A;  2PRE A;  4REZ A;  2DCC A;  1NB5 A;  2YJ2 A;  1SP4 B;  2AIM A;  3KX1 A;  4W5B A;  2FT2 A;  4PAD A;  2DC7 A;  4OVZ B;  4QH6 A;  4QRV A;  2Y6E A;  3IFU A;  1KXR A;  1MEG A;  2PAD A;  3MP2 A;  4I05 A;  1QXP A;  2UZJ A;  2YJC A;  5KO3 A;  3IMA A;  1PPP A;  4BOZ A;  4QRG A;  1GLO A;  3HD3 A;  2BDZ A;  4G54 A;  1MHW A;  1NLJ A;  4CDC B;  4X6H A;  3E1Z B;  5JA7 A;  4P6G A;  3N4C A;  4YYS A;  4IUM A;  1THE A;  2CIO A;  3K9M A;  3H6S A;  1F2C A;  3H8B A;  2BU3 A;  3S3R A;  1CV8 A;  2PNS A;  4HWY A;  1XKG A;  4BOP A;  5JH3 A;  3F5V A;  3WXE A;  2AU1 A;  1ITO A;  1AU0 A;  3TMP A;  3IEJ A;  2HH5 A;  1AYW A;  1CB5 A;  3QJ3 A;  1KFU L;  2NQI A;  2HHN A;  1PPO A;  2JQG R;  1KHQ A;  1Y4H A;  3BWK A;  2XU4 A;  3MHS A;  1AU3 A;  4BOS A;  3RVV A;  4P16 A;  1QMY A;  1FH0 A;  2AUZ A;  3ERV A;  3HHA A;  4RF0 A;  2OZ2 A;  3HHI A;  2DZY A;  1U9V A;  4MM3 B;  4YYV A;  2FYE A;  2HD5 A;  1YZB A;  4XUI A;  1AU2 A;  3KSE A;  1PPD A;  4XR7 A;  2NQD B;  3MHH A;  3W31 A;  1PVJ A;  4W4U A;  3PBH A;  5CVO B;  2R9M A;  4RY2 A;  1PIP A;  1U9Q X;  5EF4 A;  1QOL A;  2B1N A;  3LFY A;  1PAD A;  2VHS A;  3PNR A;  5E6J A;  1ME4 A;  3E9S A;  1K3B B;  4N79 A;  1BP4 A;  1JQP A;  4RKX A;  1EWO A;  1CPJ A;  2NQA A;  1MS6 A;  4YYQ A;  1YK7 A;  2YJ8 A;  3M99 A;  1DF0 A;  3O65 A;  1EWM A;  2XU1 A;  2AS8 A;  3HWN A;  1YK8 A;  4D8B A;  1X9Y A;  1M6D A;  2G8E A;  2FO5 A;  5EZS A;  1UKF A;  2IBI A;  3U8E A;  3ZUA A;  2P0R A;  2C0Y A;  5J94 A;  4A5U A;  1NL6 A;  2E03 A;  4AXM A;  4K7C A;  5JZE A;  1DEU A;  3C0R A;  2R6N A;  3USV A;  4OW0 A;  4YYR A;  2F7D A;  3MTN A;  4OEM A;  1MIR A;  3TNX A;  1NB3 A;  3N3G A;  2BTW B;  2DCA A;  2XU5 A;  3OQC A;  3CBJ A;  2JRI A;  5F02 A;  4ZUX U;  2P7U A;  2B1M A;  2OUL A;  3P5V A;  1GEC E;  1BGO A;  1HUC B;  1F2B A;  1SNK A;  1S4V A;  4BOQ A;  4GUA A;  3C9E A;  1O0E A;  2NQG A;  5FPW A;  4BOU A;  4YVA A;  2DJG B;  1U9X A;  2G6D A;  2R9C A;  3F75 A;  3PDF A;  4PP1 A;  3BPF A;  3NHE A;  1AYV A;  1TLO A;  3OVX A;  4RNA A;  1AU4 A;  1YAL A;  3B79 A;  3BCN A;  2HWK A;  4I07 A;  3OF9 A;  2AUX A;  4X6J A;  2F1G A;  3QSD A;  1ICF A;  3H7D A;  1KFX L;  3OF8 A;  4BS6 A;  1ZIV A;  1ZCM A;  1U5I A;  2Z84 A;  3PRP A;  2O6X A;  4PP2 E; 
#chains in the Genus database with same CATH homology
 1F29 A;  2AVW A;  1POP A;  3H8C A;  3WXF A;  1EF7 A;  1A6R A;  1CSB B;  2DCD A;  3BOW A;  3IHP A;  2PBH A;  1EWL A;  3CBK A;  2DC6 A;  3IUT A;  1GMY A;  3CH3 X;  5CVN B;  2FRA A;  3D9W A;  4FK5 A;  3DF0 A;  4QBB A;  1TL9 A;  3BPM A;  4MZS A;  2ATO A;  5CVM A;  3P5X A;  4X6I A;  2FUD A;  3OIS A;  2GFO A;  3P5W A;  1VJV A;  7PCK A;  1AYU A;  2H7J A;  4AXL A;  1CQD A;  2AYN A;  3MOR A;  1EWP A;  3V6E A;  2E01 A;  3WXG A;  1AEC A;  2JQF R;  3LXS A;  4CZW A;  1IWD A;  2DC9 A;  4CDF B;  2WBF X;  5CHV A;  3PW3 A;  3S3Q A;  2DC8 A;  1PBH A;  1NPZ A;  1Q6K A;  1Y08 A;  4YYU A;  1U9W A;  1QDQ A;  3O1G A;  2CB5 A;  2DJF B;  1ATK A;  5EGW A;  2E02 A;  2R9F A;  8PCH A;  3QT4 A;  4FIP A;  2R9O A;  2FQ9 A;  3AI8 A;  1CJL A;  3KFQ A;  1NQC A;  4PI3 A;  1PCI A;  3K24 A;  5K16 A;  4DMX A;  1PE6 A;  4BS5 A;  1W5R A;  1VSN A;  2VHF A;  3GCB A;  3KKU A;  3KWZ A;  4CDD B;  3V6C A;  4Q8H A;  3IV2 A;  2YJB A;  4Q8G A;  2Y5B A;  3CH2 X;  4CDE B;  1BY8 A;  2R9N A;  3RVX A;  5PAD A;  3KW9 A;  1CTE A;  2AYO A;  1CS8 A;  1BQI A;  2BDL A;  4KLB A;  4MSX A;  1TU6 A;  2XU3 A;  4I04 A;  2GHU A;  6PAD A;  4FJC A;  1AIM A;  1YT7 A;  1W6F A;  4P6E A;  1PXV A;  3O0U A;  2E00 A;  9PAP A;  3KWB X;  1STF E;  3BC3 A;  2G8J A;  2G7Y A;  2FRQ A;  1F2A A;  3I3T A;  2P86 A;  2DCB A;  2DZZ A;  2YJ9 A;  2ACT A;  4BPV A;  3OVZ A;  2ARY A;  4WA6 A;  4B55 A;  1KHP A;  4W5C A;  2FTD A;  4NV8 A;  3N3K A;  4N8W A;  1YVB A;  3RVW A;  4QRX A;  1ME3 A;  4YYW A;  3H89 A;  4OEL A;  5A24 A;  1MDW A;  4MZO A;  1CVZ A;  3IOQ A;  1MEM A;  3I06 A;  3K8U A;  4BQV A;  2IPP B;  3P5U A;  4BSQ A;  4DMY A;  5CHT A;  2VFB A;  3D6S A;  2OP3 A;  1PPN A;  4YV8 A;  1GCB A;  2HXZ A;  4N4Z A;  2PRE A;  2DCC A;  1NB5 A;  2YJ2 A;  1SP4 B;  2AIM A;  3KX1 A;  4W5B A;  2FT2 A;  4PAD A;  2DC7 A;  4QH6 A;  4QRV A;  2Y6E A;  4NV7 A;  1KXR A;  1MEG A;  2PAD A;  4I05 A;  1QXP A;  2YJC A;  3IMA A;  1PPP A;  4QRG A;  1GLO A;  3HD3 A;  2BDZ A;  4G54 A;  1MHW A;  1NLJ A;  4CDC B;  4X6H A;  3E1Z B;  5JA7 A;  4P6G A;  3N4C A;  4YYS A;  1THE A;  2CIO A;  3K9M A;  3H6S A;  1F2C A;  3H8B A;  3S3R A;  1CV8 A;  2PNS A;  4HWY A;  1XKG A;  5JH3 A;  3F5V A;  3WXE A;  2AU1 A;  1ITO A;  1AU0 A;  1E2T A;  3IEJ A;  2HH5 A;  1AYW A;  1CB5 A;  3QJ3 A;  1KFU L;  2NQI A;  2HHN A;  1PPO A;  2JQG R;  1KHQ A;  1Y4H A;  3BWK A;  2XU4 A;  3MHS A;  1AU3 A;  3RVV A;  1QMY A;  1FH0 A;  2AUZ A;  3ERV A;  3HHA A;  2OZ2 A;  3HHI A;  2DZY A;  1U9V A;  4YYV A;  2FYE A;  2HD5 A;  1GX3 A;  4XUI A;  1AU2 A;  3KSE A;  1PPD A;  4XR7 A;  2NQD B;  3MHH A;  2BSZ A;  4W4U A;  3PBH A;  5CVO B;  2R9M A;  4RY2 A;  1PIP A;  1U9Q X;  5EF4 A;  1QOL A;  2B1N A;  3LFY A;  1PAD A;  2VHS A;  3PNR A;  1ME4 A;  4GUZ A;  1K3B B;  4N79 A;  1BP4 A;  1JQP A;  1EWO A;  1CPJ A;  2NQA A;  1MS6 A;  4YYQ A;  1YK7 A;  2YJ8 A;  3M99 A;  1DF0 A;  1EWM A;  2XU1 A;  2AS8 A;  3HWN A;  1YK8 A;  1X9Y A;  1M6D A;  2G8E A;  2FO5 A;  3U8E A;  2IBI A;  3ZUA A;  2P0R A;  2C0Y A;  5J94 A;  1NL6 A;  2E03 A;  3LTW A;  4AXM A;  4K7C A;  1DEU A;  2R6N A;  3USV A;  4BGF A;  4YYR A;  2VFC A;  2F7D A;  3MTN A;  4OEM A;  1MIR A;  3TNX A;  1NB3 A;  3N3G A;  2DCA A;  2XU5 A;  3CBJ A;  5F02 A;  4ZUX U;  2P7U A;  2B1M A;  2OUL A;  3P5V A;  1GEC E;  1BGO A;  1HUC B;  1F2B A;  1SNK A;  1S4V A;  3C9E A;  1O0E A;  2NQG A;  5FPW A;  4YVA A;  2DJG B;  1U9X A;  2G6D A;  2R9C A;  3F75 A;  3PDF A;  4PP1 A;  3BPF A;  3NHE A;  1AYV A;  1TLO A;  1W4T A;  3OVX A;  4C5P A;  1AU4 A;  1YAL A;  3B79 A;  3BCN A;  4I07 A;  3OF9 A;  2AUX A;  4X6J A;  2F1G A;  3QSD A;  1ICF A;  3H7D A;  1KFX L;  3OF8 A;  4BS6 A;  1ZIV A;  1ZCM A;  1U5I A;  2O6X A;  4PP2 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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