1P42A

Crystal structure of aquifex aeolicus lpxc deacetylase (zinc-inhibited form)
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of LpxC, a Zinc-Dependent Deacetylase Essential for Endotoxin Biosynthesis
pubmed doi rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 90
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2003-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1p42A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1p42A02
2J65A 2O3ZA 4FW3A 5DRQA 3NZKA 1XXEA 4U3BA 5DRRA 5DROA 4FW5A 3P3EA 2GO4A 2JT2A 4OKGA 4LCHA 3P3GA 4J3DA 3U1YA 3PS2A 2IESA 4ISAA 4LCFA 5DRPA 4FW4A 4OZEA 3UHMA 1YH8A 2VESA 4FW7A 4MQYA 1P42A 4MDTA 2GO3A 4FW6A 3PS3A 2IERA 3P76A 3PS1A 3P3CA 1YHCA 4IS9A 4U3DA 4LCGA
chains in the Genus database with same CATH superfamily
1FI4A 4X66E 2JEBB 4LFAI 2ZBKB 4QNJA 4MU0A 1NHJA 4DR4E 4B3RE 3P3EA 4URLA 1H74A 1Z0CA 4DR1E 3U1KA 1IBMI 3JAMQ 2F4VE 4OO1E 4DV6I 1A6FA 4FW4A 4LFBE 4XTJA 3HULA 4MQYA 1WUUA 4PRXA 2VQEE 4K0KI 1IBKI 4MYTA 1VI7A 2WNRA 4B3SI 1HK7A 4LF4E 1HR0I 2JEAB 4NXME 4AIDA 4LCGA 3J7AM 2O3ZA 3K85A 5LMUI 1OYSA 4DV2E 1H72C 1XXEA 3T1HE 1XNQE 4JI5E 4FWDA 2WP8B 5DROA 2BR2A 1Z0TA 4JI6E 2PO2A 1J5EE 4DR3E 2CGEA 3P06A 1HNXE 3CDIA 5K36B 1IBLI 2C37B 4GQUA 2CVEA 4FW7A 4JV5I 1RREA 4FW6A 4AIMA 5DNLA 1N36E 4DR5E 2UXDI 2UU9I 2CZ9A 4B3ME 4JI7I 3DD6A 4FW9A 4LF9E 2V2VA 3B82A 4JI3I 2Z5BA 2V2QA 5LL6R 1E3HA 3U1YA 3Q1QA 2HK2A 3Q6NA 3J81Q 4DUYE 5K36F 4DPWA 4WUBA 2Z5CA 2PNZB 3CDJA 4LF5E 3J80Q 2JE6B 4DR7I 1E3PA 1H7SA 3WU3A 3OTOE 1N34E 2C39B 4DU8A 4HXZA 1HNZI 2UUBI 4DR6E 2HKEA 4DV5I 1B62A 1KVKA 3GONA 4FN5A 4LF7E 4DPUA 2WW4A 2DEIA 4DV3I 1FJGE 4MU1A 1FNMA 2NN6B 1N33E 5FWKA 5DNXA 4HACB 1Y60A 5K36E 2Z5EA 2CG9A 1I94E 3PYDA 1OJ4A 4N3OA 3K17A 4LF8I 2AJ4A 1XHKA 4DPTA 4JI2E 3D4JA 5LMNI 4DV7I 2VQFE 2JT2A 3GMEA 4IZKB 5IWAE 3ZZ0A 2HHHI 2V8PA 2BA1G 1Y4UA 4LFCE 1YH8A 3B8HA 1UDOA 1XMQE 2NN6F 4DU7A 4X66I 5JEAA 4DV4E 4KHPE 5BR8E 4DR4I 3LTOA 4B3RI 5FLXC 5DRQA 4OO1D 1USUA 2OI2A 3NZKA 3V5RA 5C0XD 2J7KA 4DR1I 2E1RA 1S4EA 4Z7YA 2F4VI 4PU9A 4LFBI 4Z7CA 3H1CA 5C0XC 2VQEI 4GKKE 3LNUA 4BA2A 1S16A 3P3GA 4J3DA 3PS2A 3ZZUA 4LF4I 5GMDA 3KRNA 3ZKBA 4NXMI 2ZM6E 4DPYA 4MDTA 5EKWA 1QZRA 2PO0B 4DV2I 3T1HI 1YHCA 1XNQI 2NN6E 4JI5I 4GKJE 4WUCA 4JI6I 4OO1A 1J5EI 4DR3I 4X64E 5DRRA 1HNXI 1MG7A 5C0XA 4AQYE 1HNWE 1Z0WA 1Y5YA 5A2QQ 4BA1B 5IT9Q 4OZEA 4USMA 1N36I 1Y6ZA 4DR5I 1ZXMA 3PS3A 1FWKA 4IFDD 3PS1A 2UXCE 3CWVA 3PRYA 4B3MI 2BA1D 3T1YE 1RHYA 4LF9I 2UUCE 3JAMC 3M85G 1XMOE 4IFDC 4FW5A 3GLLA 1XNRE 4DUYI 3QT6A 1FWLA 2AE8A 4LF5I 1MX0A 1N34I 3OTOI 4DV1E 2UUAE 3LPSA 2C38B 3L7ZA 4IZJB 4DR6I 2JEBA 4IFDA 2GQ0A 4P7AA 2PO1B 2V34A 4LF7I 4B3TE 1FJGI 5K36D 2UXBE 2HFSA 1N33I 2BV3A 3QT7A 4LCHA 2IOQA 4JI0E 1Z5AA 2IESA 1H7UA 4HYMA 2PNMA 1MU5A 1I94I 3HJCA 5JEAD 1N32E 2JEAA 2WNRB 4YY3E 1ELOA 4JI1E 1EA6A 4JI2I 5JEAC 2HKJA 5GMEA 2E5LE 2WP8A 2VQFI 3J81C 4ZVIA 4M1KA 3F0NA 4NXNE 4WUDA 2O1VA 5IWAI 2GO4A 3HKMA 2BR2B 4PRVA 3J80C 4LFCI 5K36A 1XMQI 1U2RA 3M85D 2C37A 2PO2B 3H4LA 4OX9E 4DV4I 4KHPI 2Q2EB 3M7NG 4JI8E 5BR8I 3PYFA 3P3CA 4X62E 4YHHE 3QT8A 4FW3A 4KQVA 4DV0E 1NHIA 2LJPA 1B63A 3ZKDA 4NBQA 2GS8A 3GCMA 4X65E 4GKKI 4JYAE 4QNKA 5ELWA 2NN6D 4OO1C 2ZM6I 4DUZE 3K1JA 2VF3A 2Z5BB 5C0XF 1PVGA 4UTGA 2PNZA 2JE6A 1P42A 1Z5CA 4GKJI 2O1WA 4JI4E 1KIJA 2Z5CB 4LF6E 2IERA 4DR2E 1Z0GA 2J65A 1DARA 2IOPA 4X64I 4IFDB 2O1TA 4AQYI 1NZ0A 1ZM2A 1HNWI 1Z5BA 2BM0A 4FWGA 3ZZTA 2R3VA 4LFAE 1Y4SA 1OYPA 5EL9A 2NPFA 1VISA 2NN6A 4EMDA 4MYUA 5DRPA 4HACA 2UXCI 5C0XE 1IBME 4UT4A 1KKHA 3T1YI 3V2UC 4DV6E 2UUCI 1XMOI 4IS9A 4U3DA 4K0KE 1IBKE 3M7ND 4B3SE 3PYGA 1HR0E 4JG4A 3PYEA 1XNRI 1UEKA 4IFDF 1R6MA 2EFGA 2R42A 4P52A 2HK3A 4IZKA 1USVA 5LMUE 3J7AG 2BA0G 2O1UA 3QT5A 2UUAI 4DV1I 2XEXA 1ZM9A 4ISAA 2VESA 2F1DA 2X36A 2BM1A 1IBLE 1Z0VA 4JV5E 5JEAB 4B3TI 5A2QC 1FKAE 4LPFA 1UDNA 2DEJA 5IT9C 2UXBI 4LOMA 4JI0I 2UXDE 1EI1A 1Z59A 2UU9E 4IFDE 4JI7E 1D6TA 1Z0BA 1N0VC 2A2DA 1N32I 4JI3E 2PNLA 4BA2B 4MU3A 3UHMA 5K36C 3B4TA 1Z0EA 2A2CA 2X7IA 4JI1I 4YY3I 3WU6A 2PO0A 1K47A 1H73A 3P76A 2E5LI 4USKA 4DXLA 4HY1A 5JEAF 3M6AA 4NXNI 4FWHA 4DR7E 4RPFA 1PIEA 4MU4A 4AM3A 2HFUA 4I3HA 4OO1B 2ZITA 4BA1A 1NHHA 4OX9I 4OKGA 3WU4A 5C0XB 1HNZE 2UUBE 4JI8I 1ZM3A 5FLXQ 1RR9A 4DV5E 1UDSA 4X62I 4IZJD 4YHHI 2BA0D 4DV3E 4ED4A 2V2ZA 4DV0I 1KTVA 3ZM7A 4X65I 4JYAI 1ZM4A 5L3JA 1ZXNA 4U3BA 4DUZI 1N0UA 5JEAE 4DPXA 3WU5A 1R6LA 4LF8E 4R1FA 4OO1F 1BKNA 1OYRA 4JI4I 5LMNE 4DV7E 4LCFA 4LF6I 3B78A 1UDQA 2C38A 2NN6C 4DR2I 1PKPA 2GO3A 2HHHE 4IZJA 2C39A 3Q6MA 2PO1A 3L7ZB
chains in the Genus database with same CATH topology
2J65A 2O3ZA 4FW3A 5DRQA 3NZKA 1XXEA 4U3BA 5DRRA 5DROA 4FW5A 3P3EA 2GO4A 2JT2A 4OKGA 4LCHA 3P3GA 4J3DA 3U1YA 3PS2A 2IESA 4ISAA 4LCFA 5DRPA 4FW4A 4OZEA 3UHMA 1YH8A 2VESA 4FW7A 4MQYA 1P42A 4MDTA 2GO3A 4FW6A 3PS3A 2IERA 3P76A 3PS1A 3P3CA 1YHCA 4IS9A 4U3DA 4LCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J65 A;  2O3Z A;  4FW3 A;  5DRQ A;  3NZK A;  1XXE A;  4U3B A;  5DRR A;  5DRO A;  4FW5 A;  3P3E A;  2GO4 A;  2JT2 A;  4OKG A;  4LCH A;  3P3G A;  4J3D A;  3U1Y A;  3PS2 A;  2IES A;  4ISA A;  4LCF A;  5DRP A;  4FW4 A;  4OZE A;  3UHM A;  1YH8 A;  2VES A;  4FW7 A;  4MQY A;  1P42 A;  4MDT A;  2GO3 A;  4FW6 A;  3PS3 A;  2IER A;  3P76 A;  3PS1 A;  3P3C A;  1YHC A;  4IS9 A;  4U3D A;  4LCG A; 
#chains in the Genus database with same CATH topology
 1FI4 A;  4X66 E;  2JEB B;  4LFA I;  2ZBK B;  4QNJ A;  4MU0 A;  1NHJ A;  4DR4 E;  4B3R E;  3P3E A;  4URL A;  1H74 A;  1Z0C A;  4DR1 E;  3U1K A;  1IBM I;  3JAM Q;  2F4V E;  4OO1 E;  4DV6 I;  1A6F A;  4FW4 A;  4LFB E;  4XTJ A;  3HUL A;  4MQY A;  1WUU A;  4PRX A;  2VQE E;  4K0K I;  1IBK I;  4MYT A;  1VI7 A;  2WNR A;  4B3S I;  1HK7 A;  4LF4 E;  1HR0 I;  2JEA B;  4NXM E;  4AID A;  4LCG A;  3J7A M;  2O3Z A;  3K85 A;  5LMU I;  1OYS A;  4DV2 E;  1H72 C;  1XXE A;  3T1H E;  1XNQ E;  4JI5 E;  4FWD A;  2WP8 B;  5DRO A;  2BR2 A;  1Z0T A;  4JI6 E;  2PO2 A;  1J5E E;  4DR3 E;  2CGE A;  3P06 A;  1HNX E;  3CDI A;  5K36 B;  1IBL I;  2C37 B;  4GQU A;  2CVE A;  4FW7 A;  4JV5 I;  1RRE A;  4FW6 A;  4AIM A;  5DNL A;  1N36 E;  4DR5 E;  2UXD I;  2UU9 I;  2CZ9 A;  4B3M E;  4JI7 I;  3DD6 A;  4FW9 A;  4LF9 E;  2V2V A;  3B82 A;  4JI3 I;  2Z5B A;  2V2Q A;  5LL6 R;  1E3H A;  3U1Y A;  3Q1Q A;  2HK2 A;  3Q6N A;  3J81 Q;  4DUY E;  5K36 F;  4DPW A;  4WUB A;  2Z5C A;  2PNZ B;  3CDJ A;  4LF5 E;  3J80 Q;  2JE6 B;  4DR7 I;  1E3P A;  1H7S A;  3WU3 A;  3OTO E;  1N34 E;  2C39 B;  4DU8 A;  4HXZ A;  1HNZ I;  2UUB I;  4DR6 E;  2HKE A;  4DV5 I;  1B62 A;  1KVK A;  3GON A;  4FN5 A;  4LF7 E;  4DPU A;  2WW4 A;  2DEI A;  4DV3 I;  1FJG E;  4MU1 A;  1FNM A;  2NN6 B;  1N33 E;  5FWK A;  5DNX A;  4HAC B;  1Y60 A;  5K36 E;  2Z5E A;  2CG9 A;  1I94 E;  3PYD A;  1OJ4 A;  4N3O A;  3K17 A;  4LF8 I;  2AJ4 A;  1XHK A;  4DPT A;  4JI2 E;  3D4J A;  5LMN I;  4DV7 I;  2VQF E;  2JT2 A;  3GME A;  4IZK B;  5IWA E;  3ZZ0 A;  2HHH I;  2V8P A;  2BA1 G;  1Y4U A;  4LFC E;  1YH8 A;  3B8H A;  1UDO A;  1XMQ E;  2NN6 F;  4DU7 A;  4X66 I;  5JEA A;  4DV4 E;  4KHP E;  5BR8 E;  4DR4 I;  3LTO A;  4B3R I;  5FLX C;  5DRQ A;  4OO1 D;  1USU A;  2OI2 A;  3NZK A;  3V5R A;  5C0X D;  2J7K A;  4DR1 I;  2E1R A;  1S4E A;  4Z7Y A;  2F4V I;  4PU9 A;  4LFB I;  4Z7C A;  3H1C A;  5C0X C;  2VQE I;  4GKK E;  3LNU A;  4BA2 A;  1S16 A;  3P3G A;  4J3D A;  3PS2 A;  3ZZU A;  4LF4 I;  5GMD A;  3KRN A;  3ZKB A;  4NXM I;  2ZM6 E;  4DPY A;  4MDT A;  5EKW A;  1QZR A;  2PO0 B;  4DV2 I;  3T1H I;  1YHC A;  1XNQ I;  2NN6 E;  4JI5 I;  4GKJ E;  4WUC A;  4JI6 I;  4OO1 A;  1J5E I;  4DR3 I;  4X64 E;  5DRR A;  1HNX I;  1MG7 A;  5C0X A;  4AQY E;  1HNW E;  1Z0W A;  1Y5Y A;  5A2Q Q;  4BA1 B;  5IT9 Q;  4OZE A;  4USM A;  1N36 I;  1Y6Z A;  4DR5 I;  1ZXM A;  3PS3 A;  1FWK A;  4IFD D;  3PS1 A;  2UXC E;  3CWV A;  3PRY A;  4B3M I;  2BA1 D;  3T1Y E;  1RHY A;  4LF9 I;  2UUC E;  3JAM C;  3M85 G;  1XMO E;  4IFD C;  4FW5 A;  3GLL A;  1XNR E;  4DUY I;  3QT6 A;  1FWL A;  2AE8 A;  4LF5 I;  1MX0 A;  1N34 I;  3OTO I;  4DV1 E;  2UUA E;  3LPS A;  2C38 B;  3L7Z A;  4IZJ B;  4DR6 I;  2JEB A;  4IFD A;  2GQ0 A;  4P7A A;  2PO1 B;  2V34 A;  4LF7 I;  4B3T E;  1FJG I;  5K36 D;  2UXB E;  2HFS A;  1N33 I;  2BV3 A;  3QT7 A;  4LCH A;  2IOQ A;  4JI0 E;  1Z5A A;  2IES A;  1H7U A;  4HYM A;  2PNM A;  1MU5 A;  1I94 I;  3HJC A;  5JEA D;  1N32 E;  2JEA A;  2WNR B;  4YY3 E;  1ELO A;  4JI1 E;  1EA6 A;  4JI2 I;  5JEA C;  2HKJ A;  5GME A;  2E5L E;  2WP8 A;  2VQF I;  3J81 C;  4ZVI A;  4M1K A;  3F0N A;  4NXN E;  4WUD A;  2O1V A;  5IWA I;  2GO4 A;  3HKM A;  2BR2 B;  4PRV A;  3J80 C;  4LFC I;  5K36 A;  1XMQ I;  1U2R A;  3M85 D;  2C37 A;  2PO2 B;  3H4L A;  4OX9 E;  4DV4 I;  4KHP I;  2Q2E B;  3M7N G;  4JI8 E;  5BR8 I;  3PYF A;  3P3C A;  4X62 E;  4YHH E;  3QT8 A;  4FW3 A;  4KQV A;  4DV0 E;  1NHI A;  2LJP A;  1B63 A;  3ZKD A;  4NBQ A;  2GS8 A;  3GCM A;  4X65 E;  4GKK I;  4JYA E;  4QNK A;  5ELW A;  2NN6 D;  4OO1 C;  2ZM6 I;  4DUZ E;  3K1J A;  2VF3 A;  2Z5B B;  5C0X F;  1PVG A;  4UTG A;  2PNZ A;  2JE6 A;  1P42 A;  1Z5C A;  4GKJ I;  2O1W A;  4JI4 E;  1KIJ A;  2Z5C B;  4LF6 E;  2IER A;  4DR2 E;  1Z0G A;  2J65 A;  1DAR A;  2IOP A;  4X64 I;  4IFD B;  2O1T A;  4AQY I;  1NZ0 A;  1ZM2 A;  1HNW I;  1Z5B A;  2BM0 A;  4FWG A;  3ZZT A;  2R3V A;  4LFA E;  1Y4S A;  1OYP A;  5EL9 A;  2NPF A;  1VIS A;  2NN6 A;  4EMD A;  4MYU A;  5DRP A;  4HAC A;  2UXC I;  5C0X E;  1IBM E;  4UT4 A;  1KKH A;  3T1Y I;  3V2U C;  4DV6 E;  2UUC I;  1XMO I;  4IS9 A;  4U3D A;  4K0K E;  1IBK E;  3M7N D;  4B3S E;  3PYG A;  1HR0 E;  4JG4 A;  3PYE A;  1XNR I;  1UEK A;  4IFD F;  1R6M A;  2EFG A;  2R42 A;  4P52 A;  2HK3 A;  4IZK A;  1USV A;  5LMU E;  3J7A G;  2BA0 G;  2O1U A;  3QT5 A;  2UUA I;  4DV1 I;  2XEX A;  1ZM9 A;  4ISA A;  2VES A;  2F1D A;  2X36 A;  2BM1 A;  1IBL E;  1Z0V A;  4JV5 E;  5JEA B;  4B3T I;  5A2Q C;  1FKA E;  4LPF A;  1UDN A;  2DEJ A;  5IT9 C;  2UXB I;  4LOM A;  4JI0 I;  2UXD E;  1EI1 A;  1Z59 A;  2UU9 E;  4IFD E;  4JI7 E;  1D6T A;  1Z0B A;  1N0V C;  2A2D A;  1N32 I;  4JI3 E;  2PNL A;  4BA2 B;  4MU3 A;  3UHM A;  5K36 C;  3B4T A;  1Z0E A;  2A2C A;  2X7I A;  4JI1 I;  4YY3 I;  3WU6 A;  2PO0 A;  1K47 A;  1H73 A;  3P76 A;  2E5L I;  4USK A;  4DXL A;  4HY1 A;  5JEA F;  3M6A A;  4NXN I;  4FWH A;  4DR7 E;  4RPF A;  1PIE A;  4MU4 A;  4AM3 A;  2HFU A;  4I3H A;  4OO1 B;  2ZIT A;  4BA1 A;  1NHH A;  4OX9 I;  4OKG A;  3WU4 A;  5C0X B;  1HNZ E;  2UUB E;  4JI8 I;  1ZM3 A;  5FLX Q;  1RR9 A;  4DV5 E;  1UDS A;  4X62 I;  4IZJ D;  4YHH I;  2BA0 D;  4DV3 E;  4ED4 A;  2V2Z A;  4DV0 I;  1KTV A;  3ZM7 A;  4X65 I;  4JYA I;  1ZM4 A;  5L3J A;  1ZXN A;  4U3B A;  4DUZ I;  1N0U A;  5JEA E;  4DPX A;  3WU5 A;  1R6L A;  4LF8 E;  4R1F A;  4OO1 F;  1BKN A;  1OYR A;  4JI4 I;  5LMN E;  4DV7 E;  4LCF A;  4LF6 I;  3B78 A;  1UDQ A;  2C38 A;  2NN6 C;  4DR2 I;  1PKP A;  2GO3 A;  2HHH E;  4IZJ A;  2C39 A;  3Q6M A;  2PO1 A;  3L7Z B; 
#chains in the Genus database with same CATH homology
 2J65 A;  2O3Z A;  4FW3 A;  5DRQ A;  3NZK A;  1XXE A;  4U3B A;  5DRR A;  5DRO A;  4FW5 A;  3P3E A;  2GO4 A;  2JT2 A;  4OKG A;  4LCH A;  3P3G A;  4J3D A;  3U1Y A;  3PS2 A;  2IES A;  4ISA A;  4LCF A;  5DRP A;  4FW4 A;  4OZE A;  3UHM A;  1YH8 A;  2VES A;  4FW7 A;  4MQY A;  1P42 A;  4MDT A;  2GO3 A;  4FW6 A;  3PS3 A;  2IER A;  3P76 A;  3PS1 A;  3P3C A;  1YHC A;  4IS9 A;  4U3D A;  4LCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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