1P42A

Crystal structure of aquifex aeolicus lpxc deacetylase (zinc-inhibited form)
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of LpxC, a Zinc-Dependent Deacetylase Essential for Endotoxin Biosynthesis
pubmed doi rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 90
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2003-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1p42A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1p42A02
4LCHA 1YHCA 2IERA 3P3CA 4MDTA 5DRQA 2O3ZA 1P42A 4J3DA 3PS1A 2VESA 5DRRA 4LCFA 4FW5A 3UHMA 4LCGA 1XXEA 2GO4A 4OZEA 4FW6A 5DRPA 2J65A 4U3DA 3NZKA 3U1YA 4ISAA 4MQYA 3P76A 3PS2A 4FW7A 4IS9A 4FW3A 2JT2A 3P3GA 2IESA 2GO3A 4FW4A 3P3EA 4OKGA 5DROA 4U3BA 1YH8A 3PS3A
chains in the Genus database with same CATH superfamily
3HKMA 1E3HA 4YHHE 1OYRA 5IWAI 1HR0I 3GCMA 4LFAE 1Z5BA 3Q1QA 1IBKI 3K17A 1Z0VA 5DRPA 5K36B 4B3TI 3J80C 2HFSA 3QT5A 4FW3A 3J81C 4JI0E 4DV2E 2IOQA 2IOPA 2LJPA 4YY3I 1XMOI 4ZVIA 5C0XD 5EKWA 2Q2EB 4URLA 3H4LA 4DV4I 1D6TA 1IBLE 2V34A 4DV3I 1Z5AA 2R42A 4PU9A 3ZM7A 5K36A 2V2VA 2O1TA 1Z0TA 5DNXA 4FW5A 4JV5I 1Z5CA 5ELWA 4LF9E 1XNQE 2CG9A 1ZM4A 3Q6NA 1J5EI 1HNXI 3B8HA 2EFGA 4FWGA 4DR7I 3U1KA 2VQEE 4DR3E 1N36E 3GONA 5K36F 4ED4A 3CWVA 3M85G 5JEAE 4DR1E 4IFDC 2JE6B 4OO1C 5LMNI 1EA6A 4LF7E 4LCGA 1I94I 4JYAE 4USKA 4JI0I 2VQFE 3ZKDA 1Y60A 3PYDA 1HNZE 5GMDA 4FW7A 3KRNA 5FLXQ 2BA1D 4WUBA 4IZJB 4LF6I 5DROA 4OX9E 2BA0D 4DV7I 2A2DA 2NN6B 2JE6A 3GLLA 1XNQI 2HK3A 3HULA 1R6MA 2HFUA 4UT4A 4DUZI 5EL9A 2JEBA 4MYUA 2UXDE 1KKHA 2C39A 4IZJA 4JI6I 2PO2B 4XTJA 4EMDA 2O1VA 2WNRB 2CGEA 2NN6A 4LFCI 1N36I 5IT9C 4NXNI 1IBKE 1XHKA 4MU4A 3ZZ0A 4IFDA 4B3TE 1FNMA 4DV1I 3GMEA 2VF3A 2ZM6I 4DR5I 4LF8E 4JYAI 1FWKA 4NXMI 2VQFI 1VI7A 4YY3E 2PO2A 1XMOE 2E5LI 1ZXMA 2WNRA 4LCFA 2CVEA 4DUYE 2PO1B 4PRXA 1UDQA 3B78A 4OZEA 4AIDA 4DV3E 1ZM2A 2NN6F 4MQYA 2XEXA 4NBQA 2UUCI 1N0UA 4FWHA 2UUAE 3F0NA 4USMA 4OO1E 5GMEA 2HHHE 1BKNA 1H7SA 3J80Q 1HNXE 1J5EE 4MYTA 3V2UC 4JI2E 2PO1A 4DR7E 3WU3A 3J81Q 3T1HI 4K0KE 2UXDI 2BA1G 4N3OA 1FKAE 2BA0G 1UDOA 1ZM9A 1UDNA 4JG4A 1S16A 2OI2A 4DV6I 4U3DA 3QT6A 1UEKA 3OTOE 3PS2A 5JEAB 1E3PA 4WUCA 1MU5A 5LMNE 1I94E 4LF8I 5C0XE 4HXZA 3PS3A 4B3RE 4DUYI 4JI7I 2UXCE 4LFBE 1EI1A 3P06A 4LF6E 2V8PA 4DV7E 5JEAA 4MU1A 2UUAI 4B3SI 2HHHI 4ISAA 2X36A 3D4JA 1H73A 3B4TA 4JI2I 4DUZE 1N33E 4K0KI 1N34I 4JI6E 2WW4A 4FN5A 1PVGA 2ZITA 2PNMA 4LFCE 2IERA 4NXNE 2E1RA 4P52A 5JEAF 4X64I 2Z5EA 4JI5I 3OTOI 4DR2E 4DV1E 2ZM6E 3PRYA 2JEAB 4DR5E 4FWDA 4NXME 4LPFA 4DR6E 2PO0B 2AE8A 4UTGA 1ZXNA 1VISA 4LF5E 4B3RI 2E5LE 3ZKBA 1RREA 4MU0A 3T1YI 4BA2B 4FW4A 2A2CA 1XNRI 2UXCI 2JEBB 4KHPI 4LFBI 2C39B 4U3BA 5A2QC 4BA1B 4GKKI 5K36D 2JEAA 3LTOA 2UUCE 2BM0A 2O3ZA 2CZ9A 5IT9Q 3Q6MA 4RPFA 2PO0A 3WU4A 4IFDB 4OO1B 3JAMC 1Z59A 5C0XC 4BA2A 3T1HE 4FW6A 1N33I 3QT7A 3PYFA 4DV5E 4WUDA 4BA1A 2F4VI 1HNWE 4I3HA 1WUUA 2HKJA 1OJ4A 4DV6E 1YH8A 3J7AM 4OO1A 4FW9A 4DR2I 4AIMA 4X65I 2C38B 5DRQA 1B62A 1R6LA 1P42A 4DR6I 2AJ4A 2VESA 5C0XB 4LF5I 2Z5BB 4HYMA 2GO4A 4JI7E 2BV3A 1OYSA 1PIEA 1U2RA 3P3GA 1Z0WA 2C38A 1NHJA 5BR8E 1XMQE 1H72C 1H7UA 2F1DA 4OKGA 4JI3E 4IFDF 4HACB 4OO1F 3QT8A 4B3SE 5C0XA 2Z5BA 1DARA 3P3CA 2BR2B 4DU8A 3PYGA 2PNZA 4DV5I 4JI1I 1N34E 1KIJA 2C37A 1HK7A 4DPYA 1NZ0A 1FWLA 1XXEA 4IZJD 1HNWI 4X62E 5K36C 2NN6D 4HACA 2PNLA 4X64E 4JI5E 1KVKA 1PKPA 2UU9I 2BR2A 1Z0BA 1RHYA 1N0VC 4GKJE 2HK2A 4B3MI 1ZM3A 5DNLA 3T1YE 4X66I 1USVA 2V2ZA 3H1CA 2Z5CB 1XNRE 4KHPE 4J3DA 1FI4A 2DEJA 3DD6A 3LPSA 5LL6R 4GKKE 3L7ZB 1ELOA 5BR8I 1XMQI 1B63A 3K1JA 4JI3I 2GQ0A 3P76A 2JT2A 4DR4I 4JI8I 3PYEA 2Z5CA 1Y4UA 2X7IA 1Z0GA 2F4VE 4LCHA 4M1KA 3L7ZA 2UXBE 4MDTA 1OYPA 4QNJA 4X62I 3ZZUA 4DPXA 4DV0E 4AM3A 4JI4I 5DRRA 5A2QQ 1IBMI 2UUBE 3UHMA 4X65E 4HY1A 1H74A 4LF4E 4AQYI 4GKJI 3CDJA 4IS9A 1MX0A 4YHHI 2V2QA 3JAMQ 3V5RA 2ZBKB 4LFAI 1UDSA 4QNKA 2NN6C 1YHCA 5K36E 4PRVA 1FJGE 3WU5A 5LMUE 5JEAD 3M7ND 3PS1A 3LNUA 1MG7A 2DEIA 1K47A 4DV2I 4DPWA 3NZKA 4JI1E 3J7AG 1IBLI 2O1WA 2UXBI 1KTVA 2GO3A 4R1FA 4P7AA 2BM1A 4DV0I 5L3JA 1N32E 2R3VA 2J7KA 2UU9E 2UUBI 4LF9I 3HJCA 1QZRA 2WP8B 4LF4I 1Y5YA 4Z7CA 1A6FA 4B3ME 5FLXC 1Y6ZA 1NHIA 5IWAE 4X66E 1HR0E 2PNZB 2J65A 2NPFA 3U1YA 2VQEI 4DR3I 2C37B 1Z0EA 2O1UA 3CDIA 1USUA 3ZZTA 2IESA 4DPUA 1FJGI 1NHHA 3P3EA 5LMUI 2WP8A 1Y4SA 4DR1I 4KQVA 4LF7I 4LOMA 4Z7YA 4DR4E 1RR9A 4JI8E 4DU7A 1HNZI 4IZKB 4DPTA 4DV4E 3WU6A 5FWKA 2GS8A 4OX9I 2NN6E 4MU3A 1N32I 3M7NG 4JI4E 3M6AA 5JEAC 1Z0CA 1IBME 4JV5E 3M85D 3K85A 2HKEA 4IFDE 4GQUA 3B82A 4IFDD 4OO1D 4AQYE 1S4EA 4IZKA 4DXLA 5C0XF
chains in the Genus database with same CATH topology
4LCHA 1YHCA 2IERA 3P3CA 4MDTA 5DRQA 2O3ZA 1P42A 4J3DA 3PS1A 2VESA 5DRRA 4LCFA 4FW5A 3UHMA 4LCGA 1XXEA 2GO4A 4OZEA 4FW6A 5DRPA 2J65A 4U3DA 3NZKA 3U1YA 4ISAA 4MQYA 3P76A 3PS2A 4FW7A 4IS9A 4FW3A 2JT2A 3P3GA 2IESA 2GO3A 4FW4A 3P3EA 4OKGA 5DROA 4U3BA 1YH8A 3PS3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LCH A;  1YHC A;  2IER A;  3P3C A;  4MDT A;  5DRQ A;  2O3Z A;  1P42 A;  4J3D A;  3PS1 A;  2VES A;  5DRR A;  4LCF A;  4FW5 A;  3UHM A;  4LCG A;  1XXE A;  2GO4 A;  4OZE A;  4FW6 A;  5DRP A;  2J65 A;  4U3D A;  3NZK A;  3U1Y A;  4ISA A;  4MQY A;  3P76 A;  3PS2 A;  4FW7 A;  4IS9 A;  4FW3 A;  2JT2 A;  3P3G A;  2IES A;  2GO3 A;  4FW4 A;  3P3E A;  4OKG A;  5DRO A;  4U3B A;  1YH8 A;  3PS3 A; 
#chains in the Genus database with same CATH topology
 3HKM A;  1E3H A;  4YHH E;  1OYR A;  5IWA I;  1HR0 I;  3GCM A;  4LFA E;  1Z5B A;  3Q1Q A;  1IBK I;  3K17 A;  1Z0V A;  5DRP A;  5K36 B;  4B3T I;  3J80 C;  2HFS A;  3QT5 A;  4FW3 A;  3J81 C;  4JI0 E;  4DV2 E;  2IOQ A;  2IOP A;  2LJP A;  4YY3 I;  1XMO I;  4ZVI A;  5C0X D;  5EKW A;  2Q2E B;  4URL A;  3H4L A;  4DV4 I;  1D6T A;  1IBL E;  2V34 A;  4DV3 I;  1Z5A A;  2R42 A;  4PU9 A;  3ZM7 A;  5K36 A;  2V2V A;  2O1T A;  1Z0T A;  5DNX A;  4FW5 A;  4JV5 I;  1Z5C A;  5ELW A;  4LF9 E;  1XNQ E;  2CG9 A;  1ZM4 A;  3Q6N A;  1J5E I;  1HNX I;  3B8H A;  2EFG A;  4FWG A;  4DR7 I;  3U1K A;  2VQE E;  4DR3 E;  1N36 E;  3GON A;  5K36 F;  4ED4 A;  3CWV A;  3M85 G;  5JEA E;  4DR1 E;  4IFD C;  2JE6 B;  4OO1 C;  5LMN I;  1EA6 A;  4LF7 E;  4LCG A;  1I94 I;  4JYA E;  4USK A;  4JI0 I;  2VQF E;  3ZKD A;  1Y60 A;  3PYD A;  1HNZ E;  5GMD A;  4FW7 A;  3KRN A;  5FLX Q;  2BA1 D;  4WUB A;  4IZJ B;  4LF6 I;  5DRO A;  4OX9 E;  2BA0 D;  4DV7 I;  2A2D A;  2NN6 B;  2JE6 A;  3GLL A;  1XNQ I;  2HK3 A;  3HUL A;  1R6M A;  2HFU A;  4UT4 A;  4DUZ I;  5EL9 A;  2JEB A;  4MYU A;  2UXD E;  1KKH A;  2C39 A;  4IZJ A;  4JI6 I;  2PO2 B;  4XTJ A;  4EMD A;  2O1V A;  2WNR B;  2CGE A;  2NN6 A;  4LFC I;  1N36 I;  5IT9 C;  4NXN I;  1IBK E;  1XHK A;  4MU4 A;  3ZZ0 A;  4IFD A;  4B3T E;  1FNM A;  4DV1 I;  3GME A;  2VF3 A;  2ZM6 I;  4DR5 I;  4LF8 E;  4JYA I;  1FWK A;  4NXM I;  2VQF I;  1VI7 A;  4YY3 E;  2PO2 A;  1XMO E;  2E5L I;  1ZXM A;  2WNR A;  4LCF A;  2CVE A;  4DUY E;  2PO1 B;  4PRX A;  1UDQ A;  3B78 A;  4OZE A;  4AID A;  4DV3 E;  1ZM2 A;  2NN6 F;  4MQY A;  2XEX A;  4NBQ A;  2UUC I;  1N0U A;  4FWH A;  2UUA E;  3F0N A;  4USM A;  4OO1 E;  5GME A;  2HHH E;  1BKN A;  1H7S A;  3J80 Q;  1HNX E;  1J5E E;  4MYT A;  3V2U C;  4JI2 E;  2PO1 A;  4DR7 E;  3WU3 A;  3J81 Q;  3T1H I;  4K0K E;  2UXD I;  2BA1 G;  4N3O A;  1FKA E;  2BA0 G;  1UDO A;  1ZM9 A;  1UDN A;  4JG4 A;  1S16 A;  2OI2 A;  4DV6 I;  4U3D A;  3QT6 A;  1UEK A;  3OTO E;  3PS2 A;  5JEA B;  1E3P A;  4WUC A;  1MU5 A;  5LMN E;  1I94 E;  4LF8 I;  5C0X E;  4HXZ A;  3PS3 A;  4B3R E;  4DUY I;  4JI7 I;  2UXC E;  4LFB E;  1EI1 A;  3P06 A;  4LF6 E;  2V8P A;  4DV7 E;  5JEA A;  4MU1 A;  2UUA I;  4B3S I;  2HHH I;  4ISA A;  2X36 A;  3D4J A;  1H73 A;  3B4T A;  4JI2 I;  4DUZ E;  1N33 E;  4K0K I;  1N34 I;  4JI6 E;  2WW4 A;  4FN5 A;  1PVG A;  2ZIT A;  2PNM A;  4LFC E;  2IER A;  4NXN E;  2E1R A;  4P52 A;  5JEA F;  4X64 I;  2Z5E A;  4JI5 I;  3OTO I;  4DR2 E;  4DV1 E;  2ZM6 E;  3PRY A;  2JEA B;  4DR5 E;  4FWD A;  4NXM E;  4LPF A;  4DR6 E;  2PO0 B;  2AE8 A;  4UTG A;  1ZXN A;  1VIS A;  4LF5 E;  4B3R I;  2E5L E;  3ZKB A;  1RRE A;  4MU0 A;  3T1Y I;  4BA2 B;  4FW4 A;  2A2C A;  1XNR I;  2UXC I;  2JEB B;  4KHP I;  4LFB I;  2C39 B;  4U3B A;  5A2Q C;  4BA1 B;  4GKK I;  5K36 D;  2JEA A;  3LTO A;  2UUC E;  2BM0 A;  2O3Z A;  2CZ9 A;  5IT9 Q;  3Q6M A;  4RPF A;  2PO0 A;  3WU4 A;  4IFD B;  4OO1 B;  3JAM C;  1Z59 A;  5C0X C;  4BA2 A;  3T1H E;  4FW6 A;  1N33 I;  3QT7 A;  3PYF A;  4DV5 E;  4WUD A;  4BA1 A;  2F4V I;  1HNW E;  4I3H A;  1WUU A;  2HKJ A;  1OJ4 A;  4DV6 E;  1YH8 A;  3J7A M;  4OO1 A;  4FW9 A;  4DR2 I;  4AIM A;  4X65 I;  2C38 B;  5DRQ A;  1B62 A;  1R6L A;  1P42 A;  4DR6 I;  2AJ4 A;  2VES A;  5C0X B;  4LF5 I;  2Z5B B;  4HYM A;  2GO4 A;  4JI7 E;  2BV3 A;  1OYS A;  1PIE A;  1U2R A;  3P3G A;  1Z0W A;  2C38 A;  1NHJ A;  5BR8 E;  1XMQ E;  1H72 C;  1H7U A;  2F1D A;  4OKG A;  4JI3 E;  4IFD F;  4HAC B;  4OO1 F;  3QT8 A;  4B3S E;  5C0X A;  2Z5B A;  1DAR A;  3P3C A;  2BR2 B;  4DU8 A;  3PYG A;  2PNZ A;  4DV5 I;  4JI1 I;  1N34 E;  1KIJ A;  2C37 A;  1HK7 A;  4DPY A;  1NZ0 A;  1FWL A;  1XXE A;  4IZJ D;  1HNW I;  4X62 E;  5K36 C;  2NN6 D;  4HAC A;  2PNL A;  4X64 E;  4JI5 E;  1KVK A;  1PKP A;  2UU9 I;  2BR2 A;  1Z0B A;  1RHY A;  1N0V C;  4GKJ E;  2HK2 A;  4B3M I;  1ZM3 A;  5DNL A;  3T1Y E;  4X66 I;  1USV A;  2V2Z A;  3H1C A;  2Z5C B;  1XNR E;  4KHP E;  4J3D A;  1FI4 A;  2DEJ A;  3DD6 A;  3LPS A;  5LL6 R;  4GKK E;  3L7Z B;  1ELO A;  5BR8 I;  1XMQ I;  1B63 A;  3K1J A;  4JI3 I;  2GQ0 A;  3P76 A;  2JT2 A;  4DR4 I;  4JI8 I;  3PYE A;  2Z5C A;  1Y4U A;  2X7I A;  1Z0G A;  2F4V E;  4LCH A;  4M1K A;  3L7Z A;  2UXB E;  4MDT A;  1OYP A;  4QNJ A;  4X62 I;  3ZZU A;  4DPX A;  4DV0 E;  4AM3 A;  4JI4 I;  5DRR A;  5A2Q Q;  1IBM I;  2UUB E;  3UHM A;  4X65 E;  4HY1 A;  1H74 A;  4LF4 E;  4AQY I;  4GKJ I;  3CDJ A;  4IS9 A;  1MX0 A;  4YHH I;  2V2Q A;  3JAM Q;  3V5R A;  2ZBK B;  4LFA I;  1UDS A;  4QNK A;  2NN6 C;  1YHC A;  5K36 E;  4PRV A;  1FJG E;  3WU5 A;  5LMU E;  5JEA D;  3M7N D;  3PS1 A;  3LNU A;  1MG7 A;  2DEI A;  1K47 A;  4DV2 I;  4DPW A;  3NZK A;  4JI1 E;  3J7A G;  1IBL I;  2O1W A;  2UXB I;  1KTV A;  2GO3 A;  4R1F A;  4P7A A;  2BM1 A;  4DV0 I;  5L3J A;  1N32 E;  2R3V A;  2J7K A;  2UU9 E;  2UUB I;  4LF9 I;  3HJC A;  1QZR A;  2WP8 B;  4LF4 I;  1Y5Y A;  4Z7C A;  1A6F A;  4B3M E;  5FLX C;  1Y6Z A;  1NHI A;  5IWA E;  4X66 E;  1HR0 E;  2PNZ B;  2J65 A;  2NPF A;  3U1Y A;  2VQE I;  4DR3 I;  2C37 B;  1Z0E A;  2O1U A;  3CDI A;  1USU A;  3ZZT A;  2IES A;  4DPU A;  1FJG I;  1NHH A;  3P3E A;  5LMU I;  2WP8 A;  1Y4S A;  4DR1 I;  4KQV A;  4LF7 I;  4LOM A;  4Z7Y A;  4DR4 E;  1RR9 A;  4JI8 E;  4DU7 A;  1HNZ I;  4IZK B;  4DPT A;  4DV4 E;  3WU6 A;  5FWK A;  2GS8 A;  4OX9 I;  2NN6 E;  4MU3 A;  1N32 I;  3M7N G;  4JI4 E;  3M6A A;  5JEA C;  1Z0C A;  1IBM E;  4JV5 E;  3M85 D;  3K85 A;  2HKE A;  4IFD E;  4GQU A;  3B82 A;  4IFD D;  4OO1 D;  4AQY E;  1S4E A;  4IZK A;  4DXL A;  5C0X F; 
#chains in the Genus database with same CATH homology
 4LCH A;  1YHC A;  2IER A;  3P3C A;  4MDT A;  5DRQ A;  2O3Z A;  1P42 A;  4J3D A;  3PS1 A;  2VES A;  5DRR A;  4LCF A;  4FW5 A;  3UHM A;  4LCG A;  1XXE A;  2GO4 A;  4OZE A;  4FW6 A;  5DRP A;  2J65 A;  4U3D A;  3NZK A;  3U1Y A;  4ISA A;  4MQY A;  3P76 A;  3PS2 A;  4FW7 A;  4IS9 A;  4FW3 A;  2JT2 A;  3P3G A;  2IES A;  2GO3 A;  4FW4 A;  3P3E A;  4OKG A;  5DRO A;  4U3B A;  1YH8 A;  3PS3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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