4OZEA

A.aolicus lpxc in complex with native product
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Mechanistic insight from the crystal structure of A.aolicus LpxC in the presence of product
rcsb
source organism Aquifex aeolicus
total genus 95
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4ozeA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4ozeA02
3P76A 1XXEA 2JT2A 2GO3A 4OZEA 4FW5A 3PS1A 3P3EA 4FW7A 4FW3A 4LCHA 2GO4A 4ISAA 2O3ZA 4FW6A 3P3GA 5DROA 3UHMA 5DRPA 4J3DA 2IERA 4FW4A 3U1YA 4IS9A 1YHCA 1P42A 4LCGA 4LCFA 4U3BA 3PS3A 5DRRA 5DRQA 2J65A 1YH8A 3NZKA 2VESA 4OKGA 2IESA 4MDTA 3P3CA 3PS2A 4U3DA 4MQYA
chains in the Genus database with same CATH superfamily
1NZ0A 1UDQA 1PVGA 5LMNE 4LFAI 4NXMI 4M1KA 1FJGE 1KVKA 3GMEA 2Z5EA 3LTOA 1MX0A 2HKJA 3ZM7A 2JE6B 1HNWE 3B8HA 4DR2I 3ZKBA 4URLA 1UEKA 1UDSA 5FWKA 3WU5A 2BA1D 3DD6A 1KKHA 2LJPA 3ZKDA 2PNZB 3Q6MA 4JI5E 2EFGA 4DR7E 5LMUI 4JYAE 5JEAF 4HXZA 4DV4E 1PIEA 2HK2A 1KIJA 4DV3I 2ZBKB 4LCHA 5IT9C 4ISAA 4KQVA 4GKKI 2JE6A 4IFDA 2IERA 2F4VI 4DPWA 1S16A 1N32E 2O1TA 1H7SA 5BR8E 2IESA 4LF6I 2BA0G 2HK3A 1IBKE 1XMOI 1USUA 2CGEA 2UUBI 2NN6A 4DPXA 1I94I 4DV5I 4Z7CA 2IOPA 2UUCE 3U1KA 1HR0E 2V2QA 3PYDA 4HACB 4DPYA 1EI1A 4DUZE 5C0XF 4LFAE 4NXME 4B3RI 2PNMA 3Q1QA 1DARA 3B4TA 4IZJB 2JEBB 2PO0A 5ELWA 3ZZ0A 2VESA 1R6LA 4BA2A 3HULA 1FI4A 4JI4E 4DR2E 2HKEA 1FKAE 2BR2A 3M6AA 4IFDE 1OYSA 3ZZUA 5C0XA 1S4EA 4DPUA 5IWAE 2O3ZA 3PYEA 3UHMA 4K0KE 4LPFA 4Z7YA 2BM0A 1Z5CA 4MU1A 4BA1B 4P52A 1Z5AA 3PYGA 1E3PA 2UXBI 4IZJA 1H73A 2JEBA 2Z5CB 4DV3E 4PRXA 2NN6E 4AQYE 1MG7A 4LOMA 1NHIA 1IBLI 1KTVA 3GLLA 4OKGA 4GKKE 3QT8A 2F4VE 2X7IA 4HYMA 1NHHA 2WNRA 3P3EA 4LF8I 1QZRA 1J5EI 4LF6E 4FWGA 1UDOA 4LF5I 1Y60A 2UUBE 4MYTA 1I94E 4DV5E 1Z0EA 1WUUA 1HNZI 1N34I 2F1DA 4IZKA 2J65A 2VQFI 2R3VA 4IZJD 4B3RE 4DR4I 2JEAA 2WW4A 3V2UC 4B3SI 3T1YI 1N36I 4JI7I 3QT5A 1XHKA 4JI0I 1OYPA 1ZM4A 4IFDB 3HJCA 4J3DA 4GKJI 1Z0BA 3T1HI 4PU9A 1ZXNA 2C38A 3F0NA 1YH8A 1RREA 3HKMA 4FWHA 1Y4UA 4JI8I 3CWVA 1ZM3A 2UU9I 4ZVIA 2NN6B 2UXBE 4UT4A 3PS1A 1IBLE 4JI3I 4MU3A 4JI1I 2BM1A 2GO4A 2O1WA 1A6FA 4DUYI 2E1RA 3LPSA 4OO1F 4IS9A 2PO0B 2GQ0A 4LF8E 4GQUA 4IFDC 4BA2B 3GONA 4JG4A 2X36A 3OTOI 5FLXC 2BR2B 5EL9A 2HHHI 1Z59A 4DR1E 3L7ZA 4FW5A 5JEAA 4FW3A 2VQFE 5C0XB 2NN6C 4DV2I 4DR4E 2UUAI 1U2RA 4QNKA 5GMDA 2HFSA 4X66I 4B3SE 2PO2A 4OO1A 3T1YE 4LFBI 3U1YA 2ZITA 4JI7E 1N36E 4WUBA 4JI0E 2V2VA 1VI7A 1FNMA 4FWDA 1IBMI 1Z0GA 4IFDD 2HFUA 5K36F 1FWKA 4EMDA 2UXDI 2BA1G 4GKJE 4B3TI 5GMEA 1B62A 4ED4A 2WNRB 4DR5I 3B78A 1VISA 2A2CA 4JI2I 2NN6D 4JI8E 4YHHI 2UU9E 3J81Q 2C39A 5C0XC 2V2ZA 5LMUE 3PYFA 1XMQI 4LF4I 3K17A 1P42A 4JI3E 4DXLA 4JI1E 4IZKB 5K36A 4WUCA 4R1FA 5DRQA 5JEAE 4KHPI 2A2DA 4MDTA 2JEAB 1HNWI 1PKPA 2DEIA 4DV6I 4DU7A 2PNLA 2Q2EB 4X62I 5FLXQ 4FW6A 3KRNA 4FN5A 2PO1A 3OTOE 2GS8A 2HHHE 1XMOE 5C0XD 1RR9A 2C38B 3P06A 1UDNA 4LCFA 4XTJA 3PS3A 2O1UA 1E3HA 4P7AA 4DV2E 3H1CA 2UUAE 3M85D 2C37A 4X66E 4MQYA 4LFBE 2Z5BA 5C0XE 4DV7I 1OYRA 4B3MI 3P76A 1HK7A 1IBME 1H74A 1N32I 2UXCI 2UXDE 4DV1I 4USKA 5A2QC 4PRVA 4B3TE 2DEJA 1Z0WA 3H4LA 5K36E 1ZM9A 4USMA 1MU5A 1HNXI 4DR6I 3J80C 4LF7I 3D4JA 2OI2A 4DU8A 4JI2E 5DRRA 1HR0I 3PRYA 4YHHE 2BA0D 3WU3A 5DNLA 2WP8A 3JAMQ 5L3JA 4DR3I 1XMQE 4LF4E 4NBQA 3CDJA 1NHJA 5LL6R 1N0UA 3L7ZB 2NPFA 4OZEA 5JEAB 4YY3I 3J81C 4KHPE 4X65I 4LFCI 3QT7A 4DPTA 4MU4A 2PO2B 4OO1B 4JI4I 2AJ4A 4IFDF 2CG9A 1B63A 2VQEI 4LCGA 4DV6E 4WUDA 2CZ9A 4X62E 1N33I 3K85A 1J5EE 3ZZTA 2IOQA 3M85G 5IWAI 4LF5E 1BKNA 4JV5I 4AIMA 1Y5YA 1R6MA 4K0KI 2E5LI 1N0VC 2J7KA 4LF9I 2NN6F 1Z0CA 2JT2A 1HNZE 1N34E 5DNXA 4N3OA 4AQYI 4NXNI 4DV7E 3B82A 5JEAC 2O1VA 5DRPA 4B3ME 1XNQI 2C39B 4JI6I 3Q6NA 5A2QQ 2UXCE 4X64I 4DV1E 5K36B 4OO1C 1XNRI 1Y4SA 2ZM6I 3J80Q 1K47A 1HNXE 4DR6E 2PNZA 4LF7E 3T1HE 4DV0I 1D6TA 2VF3A 1EA6A 2R42A 1Y6ZA 4OX9I 4UTGA 4AM3A 4I3HA 4RPFA 2PO1B 4AIDA 5JEAD 4DR3E 5EKWA 3WU6A 3M7ND 4YY3E 1ELOA 1Z0TA 5LMNI 4QNJA 1FJGI 4X65E 2AE8A 3JAMC 4LFCE 4OO1D 2V8PA 2C37B 4DUYE 4HY1A 4U3DA 2Z5BB 1FWLA 5K36C 2VQEE 1N33E 3QT6A 3GCMA 4FW7A 4OO1E 4HACA 4JV5E 4MYUA 2E5LE 4FW9A 4LF9E 3K1JA 1H7UA 1YHCA 5IT9Q 2BV3A 4JI5I 4U3BA 4DR7I 4NXNE 4JYAI 4DV4I 1ZXMA 1XNQE 2WP8B 4JI6E 3PS2A 1H72C 3LNUA 5K36D 3CDIA 1XXEA 4X64E 1Z0VA 2GO3A 1XNRE 1ZM2A 2CVEA 2ZM6E 3WU4A 1RHYA 2XEXA 3P3GA 5DROA 3V5RA 5BR8I 1USVA 4DV0E 2V34A 4FW4A 4BA1A 3M7NG 1IBKI 4DR1I 4DR5E 4OX9E 3J7AG 3J7AM 1OJ4A 2Z5CA 4MU0A 1Z5BA 2UUCI 3NZKA 3P3CA 4DUZI
chains in the Genus database with same CATH topology
3P76A 1XXEA 2JT2A 2GO3A 4OZEA 4FW5A 3PS1A 3P3EA 4FW7A 4FW3A 4LCHA 2GO4A 4ISAA 2O3ZA 4FW6A 3P3GA 5DROA 3UHMA 5DRPA 4J3DA 2IERA 4FW4A 3U1YA 4IS9A 1YHCA 1P42A 4LCGA 4LCFA 4U3BA 3PS3A 5DRRA 5DRQA 2J65A 1YH8A 3NZKA 2VESA 4OKGA 2IESA 4MDTA 3P3CA 3PS2A 4U3DA 4MQYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P76 A;  1XXE A;  2JT2 A;  2GO3 A;  4OZE A;  4FW5 A;  3PS1 A;  3P3E A;  4FW7 A;  4FW3 A;  4LCH A;  2GO4 A;  4ISA A;  2O3Z A;  4FW6 A;  3P3G A;  5DRO A;  3UHM A;  5DRP A;  4J3D A;  2IER A;  4FW4 A;  3U1Y A;  4IS9 A;  1YHC A;  1P42 A;  4LCG A;  4LCF A;  4U3B A;  3PS3 A;  5DRR A;  5DRQ A;  2J65 A;  1YH8 A;  3NZK A;  2VES A;  4OKG A;  2IES A;  4MDT A;  3P3C A;  3PS2 A;  4U3D A;  4MQY A; 
#chains in the Genus database with same CATH topology
 1NZ0 A;  1UDQ A;  1PVG A;  5LMN E;  4LFA I;  4NXM I;  4M1K A;  1FJG E;  1KVK A;  3GME A;  2Z5E A;  3LTO A;  1MX0 A;  2HKJ A;  3ZM7 A;  2JE6 B;  1HNW E;  3B8H A;  4DR2 I;  3ZKB A;  4URL A;  1UEK A;  1UDS A;  5FWK A;  3WU5 A;  2BA1 D;  3DD6 A;  1KKH A;  2LJP A;  3ZKD A;  2PNZ B;  3Q6M A;  4JI5 E;  2EFG A;  4DR7 E;  5LMU I;  4JYA E;  5JEA F;  4HXZ A;  4DV4 E;  1PIE A;  2HK2 A;  1KIJ A;  4DV3 I;  2ZBK B;  4LCH A;  5IT9 C;  4ISA A;  4KQV A;  4GKK I;  2JE6 A;  4IFD A;  2IER A;  2F4V I;  4DPW A;  1S16 A;  1N32 E;  2O1T A;  1H7S A;  5BR8 E;  2IES A;  4LF6 I;  2BA0 G;  2HK3 A;  1IBK E;  1XMO I;  1USU A;  2CGE A;  2UUB I;  2NN6 A;  4DPX A;  1I94 I;  4DV5 I;  4Z7C A;  2IOP A;  2UUC E;  3U1K A;  1HR0 E;  2V2Q A;  3PYD A;  4HAC B;  4DPY A;  1EI1 A;  4DUZ E;  5C0X F;  4LFA E;  4NXM E;  4B3R I;  2PNM A;  3Q1Q A;  1DAR A;  3B4T A;  4IZJ B;  2JEB B;  2PO0 A;  5ELW A;  3ZZ0 A;  2VES A;  1R6L A;  4BA2 A;  3HUL A;  1FI4 A;  4JI4 E;  4DR2 E;  2HKE A;  1FKA E;  2BR2 A;  3M6A A;  4IFD E;  1OYS A;  3ZZU A;  5C0X A;  1S4E A;  4DPU A;  5IWA E;  2O3Z A;  3PYE A;  3UHM A;  4K0K E;  4LPF A;  4Z7Y A;  2BM0 A;  1Z5C A;  4MU1 A;  4BA1 B;  4P52 A;  1Z5A A;  3PYG A;  1E3P A;  2UXB I;  4IZJ A;  1H73 A;  2JEB A;  2Z5C B;  4DV3 E;  4PRX A;  2NN6 E;  4AQY E;  1MG7 A;  4LOM A;  1NHI A;  1IBL I;  1KTV A;  3GLL A;  4OKG A;  4GKK E;  3QT8 A;  2F4V E;  2X7I A;  4HYM A;  1NHH A;  2WNR A;  3P3E A;  4LF8 I;  1QZR A;  1J5E I;  4LF6 E;  4FWG A;  1UDO A;  4LF5 I;  1Y60 A;  2UUB E;  4MYT A;  1I94 E;  4DV5 E;  1Z0E A;  1WUU A;  1HNZ I;  1N34 I;  2F1D A;  4IZK A;  2J65 A;  2VQF I;  2R3V A;  4IZJ D;  4B3R E;  4DR4 I;  2JEA A;  2WW4 A;  3V2U C;  4B3S I;  3T1Y I;  1N36 I;  4JI7 I;  3QT5 A;  1XHK A;  4JI0 I;  1OYP A;  1ZM4 A;  4IFD B;  3HJC A;  4J3D A;  4GKJ I;  1Z0B A;  3T1H I;  4PU9 A;  1ZXN A;  2C38 A;  3F0N A;  1YH8 A;  1RRE A;  3HKM A;  4FWH A;  1Y4U A;  4JI8 I;  3CWV A;  1ZM3 A;  2UU9 I;  4ZVI A;  2NN6 B;  2UXB E;  4UT4 A;  3PS1 A;  1IBL E;  4JI3 I;  4MU3 A;  4JI1 I;  2BM1 A;  2GO4 A;  2O1W A;  1A6F A;  4DUY I;  2E1R A;  3LPS A;  4OO1 F;  4IS9 A;  2PO0 B;  2GQ0 A;  4LF8 E;  4GQU A;  4IFD C;  4BA2 B;  3GON A;  4JG4 A;  2X36 A;  3OTO I;  5FLX C;  2BR2 B;  5EL9 A;  2HHH I;  1Z59 A;  4DR1 E;  3L7Z A;  4FW5 A;  5JEA A;  4FW3 A;  2VQF E;  5C0X B;  2NN6 C;  4DV2 I;  4DR4 E;  2UUA I;  1U2R A;  4QNK A;  5GMD A;  2HFS A;  4X66 I;  4B3S E;  2PO2 A;  4OO1 A;  3T1Y E;  4LFB I;  3U1Y A;  2ZIT A;  4JI7 E;  1N36 E;  4WUB A;  4JI0 E;  2V2V A;  1VI7 A;  1FNM A;  4FWD A;  1IBM I;  1Z0G A;  4IFD D;  2HFU A;  5K36 F;  1FWK A;  4EMD A;  2UXD I;  2BA1 G;  4GKJ E;  4B3T I;  5GME A;  1B62 A;  4ED4 A;  2WNR B;  4DR5 I;  3B78 A;  1VIS A;  2A2C A;  4JI2 I;  2NN6 D;  4JI8 E;  4YHH I;  2UU9 E;  3J81 Q;  2C39 A;  5C0X C;  2V2Z A;  5LMU E;  3PYF A;  1XMQ I;  4LF4 I;  3K17 A;  1P42 A;  4JI3 E;  4DXL A;  4JI1 E;  4IZK B;  5K36 A;  4WUC A;  4R1F A;  5DRQ A;  5JEA E;  4KHP I;  2A2D A;  4MDT A;  2JEA B;  1HNW I;  1PKP A;  2DEI A;  4DV6 I;  4DU7 A;  2PNL A;  2Q2E B;  4X62 I;  5FLX Q;  4FW6 A;  3KRN A;  4FN5 A;  2PO1 A;  3OTO E;  2GS8 A;  2HHH E;  1XMO E;  5C0X D;  1RR9 A;  2C38 B;  3P06 A;  1UDN A;  4LCF A;  4XTJ A;  3PS3 A;  2O1U A;  1E3H A;  4P7A A;  4DV2 E;  3H1C A;  2UUA E;  3M85 D;  2C37 A;  4X66 E;  4MQY A;  4LFB E;  2Z5B A;  5C0X E;  4DV7 I;  1OYR A;  4B3M I;  3P76 A;  1HK7 A;  1IBM E;  1H74 A;  1N32 I;  2UXC I;  2UXD E;  4DV1 I;  4USK A;  5A2Q C;  4PRV A;  4B3T E;  2DEJ A;  1Z0W A;  3H4L A;  5K36 E;  1ZM9 A;  4USM A;  1MU5 A;  1HNX I;  4DR6 I;  3J80 C;  4LF7 I;  3D4J A;  2OI2 A;  4DU8 A;  4JI2 E;  5DRR A;  1HR0 I;  3PRY A;  4YHH E;  2BA0 D;  3WU3 A;  5DNL A;  2WP8 A;  3JAM Q;  5L3J A;  4DR3 I;  1XMQ E;  4LF4 E;  4NBQ A;  3CDJ A;  1NHJ A;  5LL6 R;  1N0U A;  3L7Z B;  2NPF A;  4OZE A;  5JEA B;  4YY3 I;  3J81 C;  4KHP E;  4X65 I;  4LFC I;  3QT7 A;  4DPT A;  4MU4 A;  2PO2 B;  4OO1 B;  4JI4 I;  2AJ4 A;  4IFD F;  2CG9 A;  1B63 A;  2VQE I;  4LCG A;  4DV6 E;  4WUD A;  2CZ9 A;  4X62 E;  1N33 I;  3K85 A;  1J5E E;  3ZZT A;  2IOQ A;  3M85 G;  5IWA I;  4LF5 E;  1BKN A;  4JV5 I;  4AIM A;  1Y5Y A;  1R6M A;  4K0K I;  2E5L I;  1N0V C;  2J7K A;  4LF9 I;  2NN6 F;  1Z0C A;  2JT2 A;  1HNZ E;  1N34 E;  5DNX A;  4N3O A;  4AQY I;  4NXN I;  4DV7 E;  3B82 A;  5JEA C;  2O1V A;  5DRP A;  4B3M E;  1XNQ I;  2C39 B;  4JI6 I;  3Q6N A;  5A2Q Q;  2UXC E;  4X64 I;  4DV1 E;  5K36 B;  4OO1 C;  1XNR I;  1Y4S A;  2ZM6 I;  3J80 Q;  1K47 A;  1HNX E;  4DR6 E;  2PNZ A;  4LF7 E;  3T1H E;  4DV0 I;  1D6T A;  2VF3 A;  1EA6 A;  2R42 A;  1Y6Z A;  4OX9 I;  4UTG A;  4AM3 A;  4I3H A;  4RPF A;  2PO1 B;  4AID A;  5JEA D;  4DR3 E;  5EKW A;  3WU6 A;  3M7N D;  4YY3 E;  1ELO A;  1Z0T A;  5LMN I;  4QNJ A;  1FJG I;  4X65 E;  2AE8 A;  3JAM C;  4LFC E;  4OO1 D;  2V8P A;  2C37 B;  4DUY E;  4HY1 A;  4U3D A;  2Z5B B;  1FWL A;  5K36 C;  2VQE E;  1N33 E;  3QT6 A;  3GCM A;  4FW7 A;  4OO1 E;  4HAC A;  4JV5 E;  4MYU A;  2E5L E;  4FW9 A;  4LF9 E;  3K1J A;  1H7U A;  1YHC A;  5IT9 Q;  2BV3 A;  4JI5 I;  4U3B A;  4DR7 I;  4NXN E;  4JYA I;  4DV4 I;  1ZXM A;  1XNQ E;  2WP8 B;  4JI6 E;  3PS2 A;  1H72 C;  3LNU A;  5K36 D;  3CDI A;  1XXE A;  4X64 E;  1Z0V A;  2GO3 A;  1XNR E;  1ZM2 A;  2CVE A;  2ZM6 E;  3WU4 A;  1RHY A;  2XEX A;  3P3G A;  5DRO A;  3V5R A;  5BR8 I;  1USV A;  4DV0 E;  2V34 A;  4FW4 A;  4BA1 A;  3M7N G;  1IBK I;  4DR1 I;  4DR5 E;  4OX9 E;  3J7A G;  3J7A M;  1OJ4 A;  2Z5C A;  4MU0 A;  1Z5B A;  2UUC I;  3NZK A;  3P3C A;  4DUZ I; 
#chains in the Genus database with same CATH homology
 3P76 A;  1XXE A;  2JT2 A;  2GO3 A;  4OZE A;  4FW5 A;  3PS1 A;  3P3E A;  4FW7 A;  4FW3 A;  4LCH A;  2GO4 A;  4ISA A;  2O3Z A;  4FW6 A;  3P3G A;  5DRO A;  3UHM A;  5DRP A;  4J3D A;  2IER A;  4FW4 A;  3U1Y A;  4IS9 A;  1YHC A;  1P42 A;  4LCG A;  4LCF A;  4U3B A;  3PS3 A;  5DRR A;  5DRQ A;  2J65 A;  1YH8 A;  3NZK A;  2VES A;  4OKG A;  2IES A;  4MDT A;  3P3C A;  3PS2 A;  4U3D A;  4MQY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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