4OZEA

A.aolicus lpxc in complex with native product
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Mechanistic insight from the crystal structure of A.aolicus LpxC in the presence of product
rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 95
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4ozeA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4ozeA02
2GO4A 3P3EA 4FW4A 2JT2A 1P42A 4IS9A 5DROA 2GO3A 4MQYA 4U3DA 4FW3A 3PS1A 4LCHA 5DRRA 5DRPA 3NZKA 3P3CA 4FW6A 3UHMA 5DRQA 1XXEA 4ISAA 3P3GA 4J3DA 2O3ZA 2VESA 4LCFA 3P76A 4OKGA 4OZEA 2IESA 1YH8A 2IERA 4FW5A 4LCGA 3U1YA 4MDTA 3PS2A 4FW7A 4U3BA 3PS3A 1YHCA 2J65A
chains in the Genus database with same CATH superfamily
2ZITA 4DUYI 4BA1A 3M7ND 3K1JA 5A2QC 4ZVIA 4DV6I 4JYAE 4IFDF 5JEAA 2C39B 4ED4A 2UXDE 2VQFE 4IFDB 3UHMA 4DUYE 1UDQA 1N34E 5IT9Q 1D6TA 5JEAC 3P76A 4DPYA 4OO1F 1K47A 4UTGA 5IWAI 3U1KA 2PO0A 2C38A 1UDSA 2C39A 1Y4UA 5IWAE 1XNQI 2GO4A 4IFDA 1ZM2A 4JI6I 3J80C 4WUBA 5LMNI 4QNJA 1XHKA 5DRRA 4IFDC 4JI6E 4ISAA 4Z7YA 5LMNE 4LFAE 5K36E 4IFDD 2R3VA 1R6LA 2ZM6I 1PKPA 4X66I 4OO1C 1Y5YA 1PVGA 4DR5E 4OO1D 3HKMA 4R1FA 4X66E 4FW3A 4DPTA 1WUUA 4NXNE 1XNRI 3LPSA 4LOMA 1E3HA 4DV3E 2E5LI 1S4EA 5LMUI 1XMQI 4JI7I 5C0XE 1FNMA 3PYDA 1N0UA 4DPUA 3PYEA 4PRVA 1Z0GA 4FW5A 4YHHI 1XMQE 4N3OA 4JV5I 1E3PA 3ZM7A 1RHYA 1Z0BA 2V34A 3HJCA 4USMA 4YHHE 1EI1A 4OX9I 3T1YI 1I94E 4DUZE 4JI3I 2HKJA 4DV4I 3PS1A 3K17A 4JV5E 4OX9E 1ZM9A 2A2CA 5DRQA 3T1YE 4JI3E 2R42A 4DV4E 5ELWA 3P06A 1PIEA 4DR3E 4LFCE 2V2VA 3PYFA 2NN6D 3GCMA 4DV0I 2WNRB 3PS3A 4P7AA 5FLXQ 4AIMA 3JAMQ 1MG7A 2J7KA 3WU6A 3ZZUA 1XMOI 1Y60A 4NXME 2X36A 3LNUA 4LFBI 1RREA 3Q1QA 3K85A 2PNZB 1XMOE 4JI5I 1N33I 2WNRA 4JI0I 4OZEA 1S16A 2ZBKB 4LF9E 4JI5E 4AQYE 2BM1A 1USUA 1IBLE 1H7UA 2C37B 4JI0E 2HK2A 3P3EA 2JT2A 5K36F 1ZM4A 4DU7A 2PNZA 4DPWA 1Z0CA 5L3JA 2BM0A 3J80Q 4DR1E 4IZJB 1XXEA 3QT5A 4DV6E 2VQEI 4OKGA 2WW4A 4DV2I 2C37A 3WU3A 4OO1B 1NHHA 2VQEE 5DNLA 1MX0A 5C0XF 2J65A 1OYRA 4GKJI 2V2ZA 1P42A 1UDNA 2A2DA 4IZJA 4LF8I 3V5RA 5BR8I 4GKJE 4FWDA 1XNQE 2F1DA 1VISA 4HY1A 4X64I 5K36D 4I3HA 4OO1A 4DV1I 4WUDA 1QZRA 4IZJD 5DNXA 4B3MI 5JEAE 3DD6A 4HYMA 4DV1E 2WP8B 4BA2B 2JEAB 4B3ME 2ZM6E 5C0XC 4MU1A 5GMDA 2X7IA 3Q6MA 5C0XD 2UU9I 2PNLA 2NN6F 3H4LA 2F4VI 2HKEA 2NN6B 1XNRE 3M6AA 3D4JA 2WP8A 4IFDE 2E5LE 4RPFA 2IOPA 4LF7I 3F0NA 4LCGA 5LMUE 4LPFA 2JEAA 4JI7E 1H74A 1FWLA 4FW7A 3GMEA 2O1UA 1HNXI 1FJGI 2HFUA 2Q2EB 4B3RI 4LF7E 2PNMA 1HNZI 1IBMI 4URLA 1FJGE 2BA1G 2NN6A 1HNZE 1OYSA 2V8PA 4IZKB 4GKKI 3M85G 1UDOA 3Q6NA 1R6MA 1H73A 1Z59A 3ZZ0A 2NN6C 1N36I 4GKKE 1NHIA 4Z7CA 1N36E 4LF6E 4MYUA 4IZKA 5LL6R 2UXBI 4MQYA 1KVKA 2DEJA 4JI8I 4DV0E 4M1KA 2CGEA 5A2QQ 3B78A 4LF5I 3T1HI 2UXBE 3WU4A 4WUCA 2UUAI 2E1RA 1HNWI 3H1CA 4KHPI 3B4TA 4MYTA 2GS8A 4LFBE 4X62I 4LF4I 4AIDA 4JI1I 2OI2A 2UUAE 1HNWE 1Z0TA 3B8HA 2HHHI 1N33E 2O1TA 4KHPE 1B63A 1NZ0A 2JEBB 4X62E 4JI1E 1FWKA 4FWGA 3J81C 1KTVA 2HHHE 2GQ0A 5K36B 2NPFA 2UUBI 2PO1B 2IOQA 4DV7I 1Z5AA 4B3SI 5GMEA 1FKAE 4J3DA 1EA6A 4DR4I 4DV7E 4AM3A 4B3SE 2JEBA 2O1VA 4P52A 4JYAI 2PO2B 3JAMC 2DEIA 4X65I 5EL9A 2UXCI 5FWKA 2CG9A 5K36A 2PO1A 2C38B 4DV2E 1Z0EA 4FW4A 2Z5CB 4DR6I 3ZZTA 1N34I 3CDJA 4U3DA 5C0XB 2V2QA 1VI7A 4X65E 4MU0A 2UXCE 2BA0G 1UEKA 2HFSA 4JI4I 5K36C 4DR6E 4FN5A 4B3TI 3ZKBA 4LF8E 2PO2A 1Z5BA 3M7NG 2BV3A 2VESA 5BR8E 4JI4E 4NBQA 4XTJA 1U2RA 3L7ZB 5JEAD 2Z5CA 3QT6A 3U1YA 4B3TE 4X64E 5EKWA 5C0XA 4EMDA 4DU8A 2O1WA 2EFGA 3J7AG 4DXLA 4LFAI 4UT4A 4K0KI 4HACB 4LCHA 1A6FA 5IT9C 3L7ZA 3ZKDA 2VF3A 2O3ZA 3GONA 4K0KE 4JI2I 4DR5I 2IESA 1KKHA 2UU9E 2F4VE 4BA2A 2BR2B 2BA1D 4NXNI 4DV3I 4U3BA 1Z0WA 1ZXMA 2CZ9A 4JI2E 3B82A 1IBKI 1BKNA 4HACA 3M85D 3CWVA 1N0VC 4OO1E 2Z5BB 1HNXE 1IBKE 4B3RE 1Y6ZA 5DRPA 1IBME 1H72C 4PRXA 4DR7I 3QT8A 1Z5CA 3P3GA 2BR2A 1USVA 1Z0VA 1YH8A 1B62A 1I94I 4DUZI 3HULA 4KQVA 4DR7E 2Z5EA 3QT7A 4GQUA 2Z5BA 2JE6B 1ELOA 2CVEA 4PU9A 3GLLA 4LFCI 4DR3I 3J81Q 4YY3I 1OYPA 2XEXA 4MU4A 3J7AM 4FWHA 1FI4A 2LJPA 4JI8E 4LCFA 1DARA 3V2UC 1N32I 4YY3E 2UUCI 1H7SA 3WU5A 4MDTA 3T1HE 4LF5E 2JE6A 3PS2A 2NN6E 3OTOI 4NXMI 1Y4SA 4DR2I 1YHCA 3PYGA 4QNKA 1N32E 1J5EI 4FW9A 2UUCE 2AJ4A 4IS9A 3PRYA 3LTOA 4LF4E 5DROA 4USKA 1OJ4A 2GO3A 4JG4A 3KRNA 3CDIA 3OTOE 1MU5A 4DR2E 4MU3A 2HK3A 4DV5I 1J5EE 3NZKA 5JEAF 3P3CA 1ZXNA 4FW6A 4BA1B 4LF9I 1NHJA 4AQYI 5JEAB 1HR0I 4DPXA 1IBLI 4DV5E 2UUBE 1KIJA 2IERA 1ZM3A 4LF6I 1HK7A 4HXZA 5FLXC 1RR9A 2BA0D 1HR0E 2UXDI 2AE8A 4DR1I 2VQFI 4DR4E 2PO0B
chains in the Genus database with same CATH topology
2GO4A 3P3EA 4FW4A 2JT2A 1P42A 4IS9A 5DROA 2GO3A 4MQYA 4U3DA 4FW3A 3PS1A 4LCHA 5DRRA 5DRPA 3NZKA 3P3CA 4FW6A 3UHMA 5DRQA 1XXEA 4ISAA 3P3GA 4J3DA 2O3ZA 2VESA 4LCFA 3P76A 4OKGA 4OZEA 2IESA 1YH8A 2IERA 4FW5A 4LCGA 3U1YA 4MDTA 3PS2A 4FW7A 4U3BA 3PS3A 1YHCA 2J65A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GO4 A;  3P3E A;  4FW4 A;  2JT2 A;  1P42 A;  4IS9 A;  5DRO A;  2GO3 A;  4MQY A;  4U3D A;  4FW3 A;  3PS1 A;  4LCH A;  5DRR A;  5DRP A;  3NZK A;  3P3C A;  4FW6 A;  3UHM A;  5DRQ A;  1XXE A;  4ISA A;  3P3G A;  4J3D A;  2O3Z A;  2VES A;  4LCF A;  3P76 A;  4OKG A;  4OZE A;  2IES A;  1YH8 A;  2IER A;  4FW5 A;  4LCG A;  3U1Y A;  4MDT A;  3PS2 A;  4FW7 A;  4U3B A;  3PS3 A;  1YHC A;  2J65 A; 
#chains in the Genus database with same CATH topology
 2ZIT A;  4DUY I;  4BA1 A;  3M7N D;  3K1J A;  5A2Q C;  4ZVI A;  4DV6 I;  4JYA E;  4IFD F;  5JEA A;  2C39 B;  4ED4 A;  2UXD E;  2VQF E;  4IFD B;  3UHM A;  4DUY E;  1UDQ A;  1N34 E;  5IT9 Q;  1D6T A;  5JEA C;  3P76 A;  4DPY A;  4OO1 F;  1K47 A;  4UTG A;  5IWA I;  3U1K A;  2PO0 A;  2C38 A;  1UDS A;  2C39 A;  1Y4U A;  5IWA E;  1XNQ I;  2GO4 A;  4IFD A;  1ZM2 A;  4JI6 I;  3J80 C;  4WUB A;  5LMN I;  4QNJ A;  1XHK A;  5DRR A;  4IFD C;  4JI6 E;  4ISA A;  4Z7Y A;  5LMN E;  4LFA E;  5K36 E;  4IFD D;  2R3V A;  1R6L A;  2ZM6 I;  1PKP A;  4X66 I;  4OO1 C;  1Y5Y A;  1PVG A;  4DR5 E;  4OO1 D;  3HKM A;  4R1F A;  4X66 E;  4FW3 A;  4DPT A;  1WUU A;  4NXN E;  1XNR I;  3LPS A;  4LOM A;  1E3H A;  4DV3 E;  2E5L I;  1S4E A;  5LMU I;  1XMQ I;  4JI7 I;  5C0X E;  1FNM A;  3PYD A;  1N0U A;  4DPU A;  3PYE A;  4PRV A;  1Z0G A;  4FW5 A;  4YHH I;  1XMQ E;  4N3O A;  4JV5 I;  1E3P A;  3ZM7 A;  1RHY A;  1Z0B A;  2V34 A;  3HJC A;  4USM A;  4YHH E;  1EI1 A;  4OX9 I;  3T1Y I;  1I94 E;  4DUZ E;  4JI3 I;  2HKJ A;  4DV4 I;  3PS1 A;  3K17 A;  4JV5 E;  4OX9 E;  1ZM9 A;  2A2C A;  5DRQ A;  3T1Y E;  4JI3 E;  2R42 A;  4DV4 E;  5ELW A;  3P06 A;  1PIE A;  4DR3 E;  4LFC E;  2V2V A;  3PYF A;  2NN6 D;  3GCM A;  4DV0 I;  2WNR B;  3PS3 A;  4P7A A;  5FLX Q;  4AIM A;  3JAM Q;  1MG7 A;  2J7K A;  3WU6 A;  3ZZU A;  1XMO I;  1Y60 A;  4NXM E;  2X36 A;  3LNU A;  4LFB I;  1RRE A;  3Q1Q A;  3K85 A;  2PNZ B;  1XMO E;  4JI5 I;  1N33 I;  2WNR A;  4JI0 I;  4OZE A;  1S16 A;  2ZBK B;  4LF9 E;  4JI5 E;  4AQY E;  2BM1 A;  1USU A;  1IBL E;  1H7U A;  2C37 B;  4JI0 E;  2HK2 A;  3P3E A;  2JT2 A;  5K36 F;  1ZM4 A;  4DU7 A;  2PNZ A;  4DPW A;  1Z0C A;  5L3J A;  2BM0 A;  3J80 Q;  4DR1 E;  4IZJ B;  1XXE A;  3QT5 A;  4DV6 E;  2VQE I;  4OKG A;  2WW4 A;  4DV2 I;  2C37 A;  3WU3 A;  4OO1 B;  1NHH A;  2VQE E;  5DNL A;  1MX0 A;  5C0X F;  2J65 A;  1OYR A;  4GKJ I;  2V2Z A;  1P42 A;  1UDN A;  2A2D A;  4IZJ A;  4LF8 I;  3V5R A;  5BR8 I;  4GKJ E;  4FWD A;  1XNQ E;  2F1D A;  1VIS A;  4HY1 A;  4X64 I;  5K36 D;  4I3H A;  4OO1 A;  4DV1 I;  4WUD A;  1QZR A;  4IZJ D;  5DNX A;  4B3M I;  5JEA E;  3DD6 A;  4HYM A;  4DV1 E;  2WP8 B;  4BA2 B;  2JEA B;  4B3M E;  2ZM6 E;  5C0X C;  4MU1 A;  5GMD A;  2X7I A;  3Q6M A;  5C0X D;  2UU9 I;  2PNL A;  2NN6 F;  3H4L A;  2F4V I;  2HKE A;  2NN6 B;  1XNR E;  3M6A A;  3D4J A;  2WP8 A;  4IFD E;  2E5L E;  4RPF A;  2IOP A;  4LF7 I;  3F0N A;  4LCG A;  5LMU E;  4LPF A;  2JEA A;  4JI7 E;  1H74 A;  1FWL A;  4FW7 A;  3GME A;  2O1U A;  1HNX I;  1FJG I;  2HFU A;  2Q2E B;  4B3R I;  4LF7 E;  2PNM A;  1HNZ I;  1IBM I;  4URL A;  1FJG E;  2BA1 G;  2NN6 A;  1HNZ E;  1OYS A;  2V8P A;  4IZK B;  4GKK I;  3M85 G;  1UDO A;  3Q6N A;  1R6M A;  1H73 A;  1Z59 A;  3ZZ0 A;  2NN6 C;  1N36 I;  4GKK E;  1NHI A;  4Z7C A;  1N36 E;  4LF6 E;  4MYU A;  4IZK A;  5LL6 R;  2UXB I;  4MQY A;  1KVK A;  2DEJ A;  4JI8 I;  4DV0 E;  4M1K A;  2CGE A;  5A2Q Q;  3B78 A;  4LF5 I;  3T1H I;  2UXB E;  3WU4 A;  4WUC A;  2UUA I;  2E1R A;  1HNW I;  3H1C A;  4KHP I;  3B4T A;  4MYT A;  2GS8 A;  4LFB E;  4X62 I;  4LF4 I;  4AID A;  4JI1 I;  2OI2 A;  2UUA E;  1HNW E;  1Z0T A;  3B8H A;  2HHH I;  1N33 E;  2O1T A;  4KHP E;  1B63 A;  1NZ0 A;  2JEB B;  4X62 E;  4JI1 E;  1FWK A;  4FWG A;  3J81 C;  1KTV A;  2HHH E;  2GQ0 A;  5K36 B;  2NPF A;  2UUB I;  2PO1 B;  2IOQ A;  4DV7 I;  1Z5A A;  4B3S I;  5GME A;  1FKA E;  4J3D A;  1EA6 A;  4DR4 I;  4DV7 E;  4AM3 A;  4B3S E;  2JEB A;  2O1V A;  4P52 A;  4JYA I;  2PO2 B;  3JAM C;  2DEI A;  4X65 I;  5EL9 A;  2UXC I;  5FWK A;  2CG9 A;  5K36 A;  2PO1 A;  2C38 B;  4DV2 E;  1Z0E A;  4FW4 A;  2Z5C B;  4DR6 I;  3ZZT A;  1N34 I;  3CDJ A;  4U3D A;  5C0X B;  2V2Q A;  1VI7 A;  4X65 E;  4MU0 A;  2UXC E;  2BA0 G;  1UEK A;  2HFS A;  4JI4 I;  5K36 C;  4DR6 E;  4FN5 A;  4B3T I;  3ZKB A;  4LF8 E;  2PO2 A;  1Z5B A;  3M7N G;  2BV3 A;  2VES A;  5BR8 E;  4JI4 E;  4NBQ A;  4XTJ A;  1U2R A;  3L7Z B;  5JEA D;  2Z5C A;  3QT6 A;  3U1Y A;  4B3T E;  4X64 E;  5EKW A;  5C0X A;  4EMD A;  4DU8 A;  2O1W A;  2EFG A;  3J7A G;  4DXL A;  4LFA I;  4UT4 A;  4K0K I;  4HAC B;  4LCH A;  1A6F A;  5IT9 C;  3L7Z A;  3ZKD A;  2VF3 A;  2O3Z A;  3GON A;  4K0K E;  4JI2 I;  4DR5 I;  2IES A;  1KKH A;  2UU9 E;  2F4V E;  4BA2 A;  2BR2 B;  2BA1 D;  4NXN I;  4DV3 I;  4U3B A;  1Z0W A;  1ZXM A;  2CZ9 A;  4JI2 E;  3B82 A;  1IBK I;  1BKN A;  4HAC A;  3M85 D;  3CWV A;  1N0V C;  4OO1 E;  2Z5B B;  1HNX E;  1IBK E;  4B3R E;  1Y6Z A;  5DRP A;  1IBM E;  1H72 C;  4PRX A;  4DR7 I;  3QT8 A;  1Z5C A;  3P3G A;  2BR2 A;  1USV A;  1Z0V A;  1YH8 A;  1B62 A;  1I94 I;  4DUZ I;  3HUL A;  4KQV A;  4DR7 E;  2Z5E A;  3QT7 A;  4GQU A;  2Z5B A;  2JE6 B;  1ELO A;  2CVE A;  4PU9 A;  3GLL A;  4LFC I;  4DR3 I;  3J81 Q;  4YY3 I;  1OYP A;  2XEX A;  4MU4 A;  3J7A M;  4FWH A;  1FI4 A;  2LJP A;  4JI8 E;  4LCF A;  1DAR A;  3V2U C;  1N32 I;  4YY3 E;  2UUC I;  1H7S A;  3WU5 A;  4MDT A;  3T1H E;  4LF5 E;  2JE6 A;  3PS2 A;  2NN6 E;  3OTO I;  4NXM I;  1Y4S A;  4DR2 I;  1YHC A;  3PYG A;  4QNK A;  1N32 E;  1J5E I;  4FW9 A;  2UUC E;  2AJ4 A;  4IS9 A;  3PRY A;  3LTO A;  4LF4 E;  5DRO A;  4USK A;  1OJ4 A;  2GO3 A;  4JG4 A;  3KRN A;  3CDI A;  3OTO E;  1MU5 A;  4DR2 E;  4MU3 A;  2HK3 A;  4DV5 I;  1J5E E;  3NZK A;  5JEA F;  3P3C A;  1ZXN A;  4FW6 A;  4BA1 B;  4LF9 I;  1NHJ A;  4AQY I;  5JEA B;  1HR0 I;  4DPX A;  1IBL I;  4DV5 E;  2UUB E;  1KIJ A;  2IER A;  1ZM3 A;  4LF6 I;  1HK7 A;  4HXZ A;  5FLX C;  1RR9 A;  2BA0 D;  1HR0 E;  2UXD I;  2AE8 A;  4DR1 I;  2VQF I;  4DR4 E;  2PO0 B; 
#chains in the Genus database with same CATH homology
 2GO4 A;  3P3E A;  4FW4 A;  2JT2 A;  1P42 A;  4IS9 A;  5DRO A;  2GO3 A;  4MQY A;  4U3D A;  4FW3 A;  3PS1 A;  4LCH A;  5DRR A;  5DRP A;  3NZK A;  3P3C A;  4FW6 A;  3UHM A;  5DRQ A;  1XXE A;  4ISA A;  3P3G A;  4J3D A;  2O3Z A;  2VES A;  4LCF A;  3P76 A;  4OKG A;  4OZE A;  2IES A;  1YH8 A;  2IER A;  4FW5 A;  4LCG A;  3U1Y A;  4MDT A;  3PS2 A;  4FW7 A;  4U3B A;  3PS3 A;  1YHC A;  2J65 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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