4OZEA

A.aolicus lpxc in complex with native product
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
266
structure length
266
Chain Sequence
b'GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Mechanistic insight from the crystal structure of A.aolicus LpxC in the presence of product
rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 95
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4ozeA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4ozeA02
1YHCA 1XXEA 1P42A 2GO4A 2JT2A 5DRPA 4LCGA 4OZEA 4LCFA 3PS3A 3P3GA 4J3DA 4FW4A 2J65A 4FW5A 4MQYA 3U1YA 4MDTA 4U3DA 4OKGA 3P3EA 4FW7A 3PS1A 3P76A 4ISAA 3P3CA 4U3BA 2VESA 2O3ZA 4FW6A 3UHMA 2IERA 4LCHA 5DRQA 1YH8A 3NZKA 5DRRA 4FW3A 2GO3A 4IS9A 3PS2A 5DROA 2IESA
chains in the Genus database with same CATH superfamily
4MU1A 5GMEA 5FWKA 4JI6I 3K17A 4DV6I 4JI8I 4QNJA 2UXCI 1ZM4A 4JV5E 3KRNA 1KIJA 5JEAD 1EA6A 1Z5BA 1N32E 4LF8E 4DV4E 4JG4A 4R1FA 2HKEA 1IBKI 1Z0BA 1N36E 5K36A 4AQYE 1Y60A 4FW6A 1YH8A 1Z5CA 4DV2E 3WU4A 4IFDE 1NZ0A 2NN6F 4B3MI 5DROA 4X62I 4LF7E 1N0VC 3H1CA 2XEXA 1XNRE 2JEAB 4MU0A 1KKHA 4LF9E 1E3HA 1PIEA 1NHHA 4DPUA 4DV7I 4LF5E 5A2QQ 5C0XF 1FNMA 4YY3E 4DR2I 4JI6E 3ZZ0A 2C39B 4PU9A 4GKKI 5DRQA 5IWAI 4DUYI 2V34A 1UEKA 4IZJB 4OO1D 4KQVA 4LFAI 2R3VA 3OTOI 2Z5BA 3B8HA 4DR7E 3GMEA 2UUBI 3J80C 1Y5YA 4DR6I 4X62E 4IFDC 4FW5A 2J7KA 4JI3E 1XHKA 2HFSA 4DV0I 3GONA 3P3CA 4X66I 4LF4E 4DV3E 5K36B 1KTVA 2JE6A 1S16A 2IERA 1Y4UA 3ZKBA 4DR2E 2GO3A 2ZM6I 4OO1E 2BR2A 1N0UA 1S4EA 2C38B 5DRPA 4GKKE 1RR9A 2UU9E 4DUYE 1Z0EA 4BA2A 3M85D 1HNXI 4B3TE 4LFAE 4LF6E 4DPWA 3T1HE 4DV1I 5L3JA 4DR3I 2O3ZA 4M1KA 4QNKA 1H72C 2V2VA 5IT9C 3ZKDA 4JV5I 1HNWI 2PNZA 1H73A 2Z5EA 4FWGA 2ZITA 3JAMQ 3WU5A 1N32I 4P52A 4USKA 4LF8I 4DV4I 1NHJA 3M6AA 4IFDA 2BA0D 4OZEA 4DU8A 4JI1I 2C37A 2Z5BB 3ZZTA 3T1YE 1N36I 1Z0TA 4AQYI 2UXBE 2A2CA 2V8PA 4DV2I 1XMQE 5JEAA 4X64I 1Y4SA 4LF7I 2NN6C 4BA1A 4JI2E 4RPFA 1IBLI 2JE6B 4LF9I 1HNZE 4MU3A 4LF5I 2WW4A 5JEAF 4YY3I 4DV5I 2AE8A 2BR2B 1HNWE 4DR4E 1WUUA 1MU5A 4JI0E 2R42A 4BA2B 1D6TA 1U2RA 1H7SA 3U1KA 4WUCA 3QT5A 2BA1D 4FWHA 4OKGA 4KHPI 3QT7A 2GQ0A 3Q1QA 4JI1E 4B3RE 4LCHA 1MG7A 3NZKA 4DR7I 1K47A 4AM3A 1FI4A 2PNZB 4X64E 1VI7A 5K36F 1I94E 1P42A 3QT6A 2JT2A 1OYSA 1IBLE 4JI3I 3M7ND 4IFDB 1ZM3A 4OO1A 2C37B 1B63A 3J81Q 4LF4I 1ZM9A 4WUBA 4DV3I 3WU6A 3GCMA 2O1VA 2VQFI 4DV5E 4NBQA 3HULA 1XMOE 1FKAE 2EFGA 2BM0A 1J5EE 4P7AA 2UUAE 5JEAB 1H7UA 1Z0GA 4LFBE 1BKNA 4BA1B 1R6LA 4NXNE 2DEIA 5DRRA 2UU9I 1B62A 1EI1A 2BV3A 4JI5I 4KHPE 3Q6MA 5LMUI 1FWKA 1UDSA 3LTOA 4B3TI 4XTJA 2NN6D 4LF6I 3T1HI 2ZBKB 3DD6A 2CGEA 4AIDA 3J7AM 5LL6R 4U3DA 4PRXA 5C0XD 1DARA 4LOMA 5FLXQ 5A2QC 2VESA 3LNUA 3PRYA 3UHMA 1A6FA 1FJGI 4ED4A 2VQFE 1OJ4A 1RREA 2X7IA 2A2DA 2VF3A 3T1YI 2UXDI 4GQUA 2UXBI 2V2ZA 1FWLA 4PRVA 2NN6E 1XNQE 1XMQI 1Z0VA 1E3PA 4JI5E 5LMUE 4OO1B 4JI2I 2V2QA 4AIMA 4MQYA 4Z7CA 3B4TA 3CDJA 1HNZI 2CZ9A 1H74A 2CVEA 1HK7A 5C0XE 4I3HA 3LPSA 5ELWA 4LFCE 1MX0A 4GKJE 1PVGA 4FW3A 2HK2A 4DR4I 4DU7A 3F0NA 4JI0I 2WP8A 3L7ZA 1FJGE 4LCGA 2X36A 4HACA 4B3RI 4DPTA 4J3DA 4DR5E 2NPFA 2UXDE 2Z5CA 1UDQA 4LPFA 4IFDF 4JI7E 3PYGA 3M85G 1I94I 5LMNI 4USMA 1N34E 3PS2A 2PO0A 2LJPA 1YHCA 2BM1A 1XXEA 5C0XC 1XMOI 3V2UC 1Z0WA 1J5EI 3JAMC 2UUAI 4LFBI 2WNRA 3GLLA 2E5LI 4NXNI 2HFUA 2O1TA 3PS1A 4X65E 2O1WA 4ISAA 2BA0G 1OYPA 2PNLA 2OI2A 1ELOA 2JEBA 4IS9A 1RHYA 2IESA 5EL9A 4MYTA 4URLA 4B3SI 2UUCE 2WP8B 3L7ZB 1USVA 1HR0E 2PO1A 5LMNE 1N33I 2F1DA 4WUDA 1USUA 4DPYA 1NHIA 4HACB 2J65A 5BR8E 2NN6A 2PO2A 4IZJD 2Z5CB 4HYMA 1UDOA 1PKPA 2DEJA 2HHHI 4JI4I 4OO1F 2AJ4A 2E5LE 4DR1I 1XNQI 5C0XA 3J80Q 2HK3A 2C38A 2BA1G 3B82A 4JYAE 2PO0B 4DXLA 4YHHI 2F4VI 3K1JA 4FWDA 5JEAE 4K0KE 5K36D 4LFCI 4DV6E 4B3SE 1OYRA 4MDTA 4JI8E 5EKWA 2WNRB 4GKJI 3P3EA 2UXCE 3HJCA 1Y6ZA 1Z59A 2CG9A 1N33E 2VQEI 3M7NG 3J81C 1IBKE 4N3OA 3WU3A 2O1UA 3Q6NA 4ZVIA 4MU4A 2JEBB 4DR5I 4UT4A 3P06A 3ZZUA 2GO4A 1IBMI 2HHHE 4JI4E 1R6MA 3P3GA 4DR1E 4B3ME 2PO1B 4JI7I 5K36E 4FW4A 5IT9Q 2IOQA 1QZRA 1ZXNA 3PYFA 3K85A 2NN6B 2PO2B 4EMDA 4YHHE 1KVKA 3H4LA 1N34I 4DV7E 2F4VE 3QT8A 5JEAC 4IZKA 4UTGA 2GS8A 2PNMA 5FLXC 5C0XB 2VQEE 4OX9I 4DUZI 4NXMI 1Z5AA 3ZM7A 1Z0CA 5IWAE 5DNLA 4X65I 4MYUA 2IOPA 3HKMA 4HXZA 4FN5A 3OTOE 2E1RA 1IBME 4FW7A 3D4JA 2UUBE 4DR6E 4FW9A 4DPXA 2UUCI 3J7AG 5GMDA 4HY1A 4Z7YA 1HR0I 5K36C 4DV0E 3CDIA 4X66E 1ZXMA 2JEAA 5DNXA 5BR8I 3B78A 3PYDA 4LCFA 3PS3A 3PYEA 2ZM6E 4OX9E 4DUZE 1VISA 4NXME 3U1YA 2C39A 3CWVA 4OO1C 2HKJA 2Q2EB 3P76A 1UDNA 1XNRI 1HNXE 4U3BA 4JYAI 4IFDD 4IZJA 1ZM2A 4DV1E 3V5RA 4IZKB 4K0KI 4DR3E
chains in the Genus database with same CATH topology
1YHCA 1XXEA 1P42A 2GO4A 2JT2A 5DRPA 4LCGA 4OZEA 4LCFA 3PS3A 3P3GA 4J3DA 4FW4A 2J65A 4FW5A 4MQYA 3U1YA 4MDTA 4U3DA 4OKGA 3P3EA 4FW7A 3PS1A 3P76A 4ISAA 3P3CA 4U3BA 2VESA 2O3ZA 4FW6A 3UHMA 2IERA 4LCHA 5DRQA 1YH8A 3NZKA 5DRRA 4FW3A 2GO3A 4IS9A 3PS2A 5DROA 2IESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YHC A;  1XXE A;  1P42 A;  2GO4 A;  2JT2 A;  5DRP A;  4LCG A;  4OZE A;  4LCF A;  3PS3 A;  3P3G A;  4J3D A;  4FW4 A;  2J65 A;  4FW5 A;  4MQY A;  3U1Y A;  4MDT A;  4U3D A;  4OKG A;  3P3E A;  4FW7 A;  3PS1 A;  3P76 A;  4ISA A;  3P3C A;  4U3B A;  2VES A;  2O3Z A;  4FW6 A;  3UHM A;  2IER A;  4LCH A;  5DRQ A;  1YH8 A;  3NZK A;  5DRR A;  4FW3 A;  2GO3 A;  4IS9 A;  3PS2 A;  5DRO A;  2IES A; 
#chains in the Genus database with same CATH topology
 4MU1 A;  5GME A;  5FWK A;  4JI6 I;  3K17 A;  4DV6 I;  4JI8 I;  4QNJ A;  2UXC I;  1ZM4 A;  4JV5 E;  3KRN A;  1KIJ A;  5JEA D;  1EA6 A;  1Z5B A;  1N32 E;  4LF8 E;  4DV4 E;  4JG4 A;  4R1F A;  2HKE A;  1IBK I;  1Z0B A;  1N36 E;  5K36 A;  4AQY E;  1Y60 A;  4FW6 A;  1YH8 A;  1Z5C A;  4DV2 E;  3WU4 A;  4IFD E;  1NZ0 A;  2NN6 F;  4B3M I;  5DRO A;  4X62 I;  4LF7 E;  1N0V C;  3H1C A;  2XEX A;  1XNR E;  2JEA B;  4MU0 A;  1KKH A;  4LF9 E;  1E3H A;  1PIE A;  1NHH A;  4DPU A;  4DV7 I;  4LF5 E;  5A2Q Q;  5C0X F;  1FNM A;  4YY3 E;  4DR2 I;  4JI6 E;  3ZZ0 A;  2C39 B;  4PU9 A;  4GKK I;  5DRQ A;  5IWA I;  4DUY I;  2V34 A;  1UEK A;  4IZJ B;  4OO1 D;  4KQV A;  4LFA I;  2R3V A;  3OTO I;  2Z5B A;  3B8H A;  4DR7 E;  3GME A;  2UUB I;  3J80 C;  1Y5Y A;  4DR6 I;  4X62 E;  4IFD C;  4FW5 A;  2J7K A;  4JI3 E;  1XHK A;  2HFS A;  4DV0 I;  3GON A;  3P3C A;  4X66 I;  4LF4 E;  4DV3 E;  5K36 B;  1KTV A;  2JE6 A;  1S16 A;  2IER A;  1Y4U A;  3ZKB A;  4DR2 E;  2GO3 A;  2ZM6 I;  4OO1 E;  2BR2 A;  1N0U A;  1S4E A;  2C38 B;  5DRP A;  4GKK E;  1RR9 A;  2UU9 E;  4DUY E;  1Z0E A;  4BA2 A;  3M85 D;  1HNX I;  4B3T E;  4LFA E;  4LF6 E;  4DPW A;  3T1H E;  4DV1 I;  5L3J A;  4DR3 I;  2O3Z A;  4M1K A;  4QNK A;  1H72 C;  2V2V A;  5IT9 C;  3ZKD A;  4JV5 I;  1HNW I;  2PNZ A;  1H73 A;  2Z5E A;  4FWG A;  2ZIT A;  3JAM Q;  3WU5 A;  1N32 I;  4P52 A;  4USK A;  4LF8 I;  4DV4 I;  1NHJ A;  3M6A A;  4IFD A;  2BA0 D;  4OZE A;  4DU8 A;  4JI1 I;  2C37 A;  2Z5B B;  3ZZT A;  3T1Y E;  1N36 I;  1Z0T A;  4AQY I;  2UXB E;  2A2C A;  2V8P A;  4DV2 I;  1XMQ E;  5JEA A;  4X64 I;  1Y4S A;  4LF7 I;  2NN6 C;  4BA1 A;  4JI2 E;  4RPF A;  1IBL I;  2JE6 B;  4LF9 I;  1HNZ E;  4MU3 A;  4LF5 I;  2WW4 A;  5JEA F;  4YY3 I;  4DV5 I;  2AE8 A;  2BR2 B;  1HNW E;  4DR4 E;  1WUU A;  1MU5 A;  4JI0 E;  2R42 A;  4BA2 B;  1D6T A;  1U2R A;  1H7S A;  3U1K A;  4WUC A;  3QT5 A;  2BA1 D;  4FWH A;  4OKG A;  4KHP I;  3QT7 A;  2GQ0 A;  3Q1Q A;  4JI1 E;  4B3R E;  4LCH A;  1MG7 A;  3NZK A;  4DR7 I;  1K47 A;  4AM3 A;  1FI4 A;  2PNZ B;  4X64 E;  1VI7 A;  5K36 F;  1I94 E;  1P42 A;  3QT6 A;  2JT2 A;  1OYS A;  1IBL E;  4JI3 I;  3M7N D;  4IFD B;  1ZM3 A;  4OO1 A;  2C37 B;  1B63 A;  3J81 Q;  4LF4 I;  1ZM9 A;  4WUB A;  4DV3 I;  3WU6 A;  3GCM A;  2O1V A;  2VQF I;  4DV5 E;  4NBQ A;  3HUL A;  1XMO E;  1FKA E;  2EFG A;  2BM0 A;  1J5E E;  4P7A A;  2UUA E;  5JEA B;  1H7U A;  1Z0G A;  4LFB E;  1BKN A;  4BA1 B;  1R6L A;  4NXN E;  2DEI A;  5DRR A;  2UU9 I;  1B62 A;  1EI1 A;  2BV3 A;  4JI5 I;  4KHP E;  3Q6M A;  5LMU I;  1FWK A;  1UDS A;  3LTO A;  4B3T I;  4XTJ A;  2NN6 D;  4LF6 I;  3T1H I;  2ZBK B;  3DD6 A;  2CGE A;  4AID A;  3J7A M;  5LL6 R;  4U3D A;  4PRX A;  5C0X D;  1DAR A;  4LOM A;  5FLX Q;  5A2Q C;  2VES A;  3LNU A;  3PRY A;  3UHM A;  1A6F A;  1FJG I;  4ED4 A;  2VQF E;  1OJ4 A;  1RRE A;  2X7I A;  2A2D A;  2VF3 A;  3T1Y I;  2UXD I;  4GQU A;  2UXB I;  2V2Z A;  1FWL A;  4PRV A;  2NN6 E;  1XNQ E;  1XMQ I;  1Z0V A;  1E3P A;  4JI5 E;  5LMU E;  4OO1 B;  4JI2 I;  2V2Q A;  4AIM A;  4MQY A;  4Z7C A;  3B4T A;  3CDJ A;  1HNZ I;  2CZ9 A;  1H74 A;  2CVE A;  1HK7 A;  5C0X E;  4I3H A;  3LPS A;  5ELW A;  4LFC E;  1MX0 A;  4GKJ E;  1PVG A;  4FW3 A;  2HK2 A;  4DR4 I;  4DU7 A;  3F0N A;  4JI0 I;  2WP8 A;  3L7Z A;  1FJG E;  4LCG A;  2X36 A;  4HAC A;  4B3R I;  4DPT A;  4J3D A;  4DR5 E;  2NPF A;  2UXD E;  2Z5C A;  1UDQ A;  4LPF A;  4IFD F;  4JI7 E;  3PYG A;  3M85 G;  1I94 I;  5LMN I;  4USM A;  1N34 E;  3PS2 A;  2PO0 A;  2LJP A;  1YHC A;  2BM1 A;  1XXE A;  5C0X C;  1XMO I;  3V2U C;  1Z0W A;  1J5E I;  3JAM C;  2UUA I;  4LFB I;  2WNR A;  3GLL A;  2E5L I;  4NXN I;  2HFU A;  2O1T A;  3PS1 A;  4X65 E;  2O1W A;  4ISA A;  2BA0 G;  1OYP A;  2PNL A;  2OI2 A;  1ELO A;  2JEB A;  4IS9 A;  1RHY A;  2IES A;  5EL9 A;  4MYT A;  4URL A;  4B3S I;  2UUC E;  2WP8 B;  3L7Z B;  1USV A;  1HR0 E;  2PO1 A;  5LMN E;  1N33 I;  2F1D A;  4WUD A;  1USU A;  4DPY A;  1NHI A;  4HAC B;  2J65 A;  5BR8 E;  2NN6 A;  2PO2 A;  4IZJ D;  2Z5C B;  4HYM A;  1UDO A;  1PKP A;  2DEJ A;  2HHH I;  4JI4 I;  4OO1 F;  2AJ4 A;  2E5L E;  4DR1 I;  1XNQ I;  5C0X A;  3J80 Q;  2HK3 A;  2C38 A;  2BA1 G;  3B82 A;  4JYA E;  2PO0 B;  4DXL A;  4YHH I;  2F4V I;  3K1J A;  4FWD A;  5JEA E;  4K0K E;  5K36 D;  4LFC I;  4DV6 E;  4B3S E;  1OYR A;  4MDT A;  4JI8 E;  5EKW A;  2WNR B;  4GKJ I;  3P3E A;  2UXC E;  3HJC A;  1Y6Z A;  1Z59 A;  2CG9 A;  1N33 E;  2VQE I;  3M7N G;  3J81 C;  1IBK E;  4N3O A;  3WU3 A;  2O1U A;  3Q6N A;  4ZVI A;  4MU4 A;  2JEB B;  4DR5 I;  4UT4 A;  3P06 A;  3ZZU A;  2GO4 A;  1IBM I;  2HHH E;  4JI4 E;  1R6M A;  3P3G A;  4DR1 E;  4B3M E;  2PO1 B;  4JI7 I;  5K36 E;  4FW4 A;  5IT9 Q;  2IOQ A;  1QZR A;  1ZXN A;  3PYF A;  3K85 A;  2NN6 B;  2PO2 B;  4EMD A;  4YHH E;  1KVK A;  3H4L A;  1N34 I;  4DV7 E;  2F4V E;  3QT8 A;  5JEA C;  4IZK A;  4UTG A;  2GS8 A;  2PNM A;  5FLX C;  5C0X B;  2VQE E;  4OX9 I;  4DUZ I;  4NXM I;  1Z5A A;  3ZM7 A;  1Z0C A;  5IWA E;  5DNL A;  4X65 I;  4MYU A;  2IOP A;  3HKM A;  4HXZ A;  4FN5 A;  3OTO E;  2E1R A;  1IBM E;  4FW7 A;  3D4J A;  2UUB E;  4DR6 E;  4FW9 A;  4DPX A;  2UUC I;  3J7A G;  5GMD A;  4HY1 A;  4Z7Y A;  1HR0 I;  5K36 C;  4DV0 E;  3CDI A;  4X66 E;  1ZXM A;  2JEA A;  5DNX A;  5BR8 I;  3B78 A;  3PYD A;  4LCF A;  3PS3 A;  3PYE A;  2ZM6 E;  4OX9 E;  4DUZ E;  1VIS A;  4NXM E;  3U1Y A;  2C39 A;  3CWV A;  4OO1 C;  2HKJ A;  2Q2E B;  3P76 A;  1UDN A;  1XNR I;  1HNX E;  4U3B A;  4JYA I;  4IFD D;  4IZJ A;  1ZM2 A;  4DV1 E;  3V5R A;  4IZK B;  4K0K I;  4DR3 E; 
#chains in the Genus database with same CATH homology
 1YHC A;  1XXE A;  1P42 A;  2GO4 A;  2JT2 A;  5DRP A;  4LCG A;  4OZE A;  4LCF A;  3PS3 A;  3P3G A;  4J3D A;  4FW4 A;  2J65 A;  4FW5 A;  4MQY A;  3U1Y A;  4MDT A;  4U3D A;  4OKG A;  3P3E A;  4FW7 A;  3PS1 A;  3P76 A;  4ISA A;  3P3C A;  4U3B A;  2VES A;  2O3Z A;  4FW6 A;  3UHM A;  2IER A;  4LCH A;  5DRQ A;  1YH8 A;  3NZK A;  5DRR A;  4FW3 A;  2GO3 A;  4IS9 A;  3PS2 A;  5DRO A;  2IES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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