4OZEA

A.aolicus lpxc in complex with native product
Total Genus 95
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
95
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Mechanistic insight from the crystal structure of A.aolicus LpxC in the presence of product
rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 95
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-02-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4ozeA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4ozeA02
4OKGA 4ISAA 3P3GA 3NZKA 3PS2A 1XXEA 4MQYA 3P3EA 3P76A 4J3DA 3U1YA 5DRPA 3P3CA 4LCGA 2GO4A 2GO3A 4U3DA 2JT2A 2O3ZA 4FW5A 4OZEA 4FW3A 4LCHA 4FW4A 1YH8A 4MDTA 5DRRA 2VESA 4FW7A 5DROA 4IS9A 3UHMA 1P42A 4LCFA 1YHCA 2IERA 2IESA 3PS1A 5DRQA 4U3BA 2J65A 3PS3A 4FW6A
chains in the Genus database with same CATH superfamily
4LOMA 2R3VA 2Q2EB 5LL6R 4DR6I 5K36A 1S16A 4Z7YA 2PO1B 4U3DA 2UUCE 2O3ZA 2WP8B 2A2CA 5IT9Q 2UU9E 3B8HA 5DROA 3H1CA 1Z5AA 4DV0I 3JAMQ 5C0XB 1NZ0A 4URLA 2V2QA 4U3BA 3PS1A 4DR6E 2BM0A 3P3GA 1E3HA 1ZM3A 4JI8I 3PRYA 4AQYI 4LFCI 2JE6A 2DEJA 4P52A 4J3DA 2HFSA 4JG4A 2EFGA 2JT2A 5DNXA 4KHPI 4DV0E 3QT8A 4X64I 1UDOA 3T1YI 2JEBA 4IZJD 4DR1I 4DV5I 2HHHI 4JI0I 4IFDF 1Z5BA 4OO1D 3ZZUA 4ZVIA 4JI8E 4AQYE 4LFAI 4WUCA 1XNQI 4FW6A 4YHHE 4IZJA 2O1UA 3PS2A 4KHPE 4X64E 4WUBA 4JI7E 4OO1A 4DR5I 2VQFI 3T1YE 5K36C 2HHHE 4DR1E 4DV5E 1EI1A 3V5RA 4JI0E 5FWKA 3U1KA 4FW5A 2HFUA 1HNXI 4DXLA 3J7AM 2ZITA 2NN6E 4B3SI 4MDTA 4FW7A 4AIMA 2C37B 4BA1A 4LFAE 1XNQE 2V2ZA 5EL9A 4LCFA 1Z0GA 5C0XE 3ZM7A 1R6MA 2WW4A 4MU0A 4DR5E 4NBQA 5EKWA 3P3EA 2Z5BA 3U1YA 1KIJA 1PVGA 2O1TA 4DV3I 1IBKI 4HY1A 1Y6ZA 2JE6B 5GMEA 4DV4E 2Z5CA 1ZXNA 1N33I 4Z7CA 5A2QQ 4FWHA 4HACA 2ZM6I 5BR8I 2BA0G 4DV3E 1IBKE 3PYEA 4OO1C 5ELWA 5FLXQ 1NHJA 4LF6I 4IZJB 2BR2A 4GKKI 4IFDB 2VESA 1KVKA 4HYMA 2PNZA 5JEAD 2X36A 2ZM6E 5BR8E 2IESA 5K36D 2CG9A 4MU3A 3PS3A 1H72C 4M1KA 4BA1B 2JEAA 3ZZTA 2PNMA 5JEAA 3NZKA 4PU9A 4LF6E 1UDSA 2NPFA 1N0VC 4GKKE 2WNRB 1EA6A 4FW9A 4X66I 3CDJA 3B78A 4DV7I 1N32I 2OI2A 1RHYA 1ELOA 4JI5I 4NXNI 1UDQA 3GMEA 4IS9A 4B3MI 4OX9I 3CDIA 3HJCA 3M7ND 4DV1E 4MYUA 2J65A 2O1WA 4DPYA 4OKGA 4X62I 2UXCI 4UT4A 4BA2A 3V2UC 4MYTA 2HKEA 4DUZI 4JYAI 4X66E 4DPTA 3F0NA 2Z5CB 4DV7E 4AM3A 1N32E 4YY3I 2C38A 4YHHI 4JI5E 2GO4A 4JI6I 4NXNE 4HACB 4B3ME 4OX9E 5LMNI 1Z0BA 3PYGA 5GMDA 1NHHA 5LMUE 3GCMA 4IFDE 4JI7I 1YH8A 3P06A 2A2DA 1HNWE 4DV6I 1U2RA 4X62E 2UXCE 2C39B 1P42A 2R42A 4LF9I 1DARA 1Z5CA 4OO1F 4DUZE 4B3TI 4JYAE 2BR2B 1H7UA 4YY3E 3J80C 5JEAC 2UXBI 4JI6E 1ZM2A 2GQ0A 3K85A 5LMNE 4N3OA 4LFBI 2UUBI 3WU4A 4DR3E 1XHKA 3P3CA 4JI4I 2PO2B 1S4EA 4IZKA 4DV6E 1QZRA 4LF9E 4B3TE 4AIDA 1XMOI 1HNZI 1E3PA 4JI1I 5K36B 1Y60A 2UXBE 2F4VI 4LFBE 2UUBE 4JI2E 4ISAA 4JI4E 3OTOI 4DV4I 2UUAE 4R1FA 2CZ9A 3PYDA 1ZM9A 3M85D 1XMOE 4DUYI 1HNZE 4JI1E 4BA2B 1Y4SA 3L7ZA 4DPWA 2F4VE 2NN6D 2BA1D 1A6FA 3OTOE 2Z5EA 4DV2E 2PO1A 4QNKA 1H73A 2WP8A 3Q1QA 4DUYE 2JEBB 1NHIA 4WUDA 3KRNA 2NN6A 4K0KE 3P76A 1Z0EA 2GO3A 5C0XA 1FJGE 2O1VA 2BM1A 3WU3A 4LCHA 1IBLI 1WUUA 5JEAF 1VI7A 4FWDA 1XNRI 4XTJA 4OO1B 1USUA 3UHMA 2E1RA 1YHCA 1KTVA 4HXZA 4IZKB 4LF7I 3WU5A 1FNMA 1FKAE 5K36F 2PO0A 1D6TA 2VF3A 1ZM4A 4DR7I 2HK3A 2DEIA 5IT9C 3LTOA 4MQYA 4DV1I 1HR0I 4DR2E 1MG7A 4DR4I 3CWVA 4FWGA 1IBLE 4DU8A 4LPFA 4LCGA 1I94E 1XNRE 3GLLA 4USMA 2IOPA 3GONA 1N36I 1OYRA 4LF7E 3J7AG 2ZBKB 4LF4I 1OYSA 4DR7E 2Z5BB 1HK7A 3QT5A 3QT6A 1OJ4A 1XMQI 5DRQA 5LMUI 1IBMI 1HR0E 4JI3I 4DR4E 1HNWI 3L7ZB 2C37A 2NN6C 1RR9A 2J7KA 3T1HI 1N36E 1FWKA 2V2VA 1Z0WA 4LF4E 1Z0TA 5C0XC 4FW3A 2HK2A 2NN6B 1XMQE 1IBME 4JI3E 4LF8I 4DR3I 4OO1E 2AJ4A 2IERA 3J81C 3T1HE 4JV5I 1MU5A 2CGEA 2PNZB 3B82A 1MX0A 1XXEA 1J5EI 1K47A 2X7IA 3Q6NA 3M6AA 4NXMI 3K17A 2PO0B 4LF8E 4JI2I 1BKNA 3K1JA 1B63A 4P7AA 1UDNA 2UUAI 2JEAB 5JEAB 3H4LA 3M7NG 4JV5E 4IFDD 4LF5I 4LFCE 1J5EE 3HKMA 5DNLA 1Y4UA 4NXME 2PNLA 4DPUA 4IFDA 4X65I 3J81Q 4DV2I 2V34A 4QNJA 3Q6MA 5IWAI 2BA0D 2E5LI 1OYPA 3J80Q 1ZXMA 1KKHA 1H74A 2BV3A 1N34I 4LF5E 4K0KI 4FW4A 5A2QC 4UTGA 4B3RI 4GKJI 1PKPA 3PYFA 2NN6F 4KQVA 4EMDA 2UXDI 2C38B 1FJGI 4X65E 2WNRA 2VQFE 3ZZ0A 5C0XF 5IWAE 5FLXC 5C0XD 3QT7A 4RPFA 2E5LE 1HNXE 3WU6A 4DPXA 2HKJA 1N34E 1UEKA 4B3SE 5DRPA 1Z0CA 1FI4A 3LPSA 1VISA 4B3RE 1Y5YA 4GKJE 4MU4A 3B4TA 4ED4A 1FWLA 2IOQA 4USKA 5JEAE 1H7SA 2UXDE 4DR2I 5DRRA 2GS8A 3D4JA 1I94I 5K36E 1R6LA 2V8PA 3LNUA 3HULA 1Z0VA 2LJPA 3ZKDA 1B62A 1N0UA 1USVA 4DU7A 4I3HA 3ZKBA 3M85G 4IFDC 2VQEI 4GQUA 3DD6A 2C39A 3JAMC 4OZEA 2F1DA 2BA1G 1Z59A 1N33E 4PRXA 4PRVA 2CVEA 4MU1A 2AE8A 5L3JA 2UUCI 2XEXA 2VQEE 2UU9I 4FN5A 2PO2A 1RREA 1PIEA
chains in the Genus database with same CATH topology
4OKGA 4ISAA 3P3GA 3NZKA 3PS2A 1XXEA 4MQYA 3P3EA 3P76A 4J3DA 3U1YA 5DRPA 3P3CA 4LCGA 2GO4A 2GO3A 4U3DA 2JT2A 2O3ZA 4FW5A 4OZEA 4FW3A 4LCHA 4FW4A 1YH8A 4MDTA 5DRRA 2VESA 4FW7A 5DROA 4IS9A 3UHMA 1P42A 4LCFA 1YHCA 2IERA 2IESA 3PS1A 5DRQA 4U3BA 2J65A 3PS3A 4FW6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OKG A;  4ISA A;  3P3G A;  3NZK A;  3PS2 A;  1XXE A;  4MQY A;  3P3E A;  3P76 A;  4J3D A;  3U1Y A;  5DRP A;  3P3C A;  4LCG A;  2GO4 A;  2GO3 A;  4U3D A;  2JT2 A;  2O3Z A;  4FW5 A;  4OZE A;  4FW3 A;  4LCH A;  4FW4 A;  1YH8 A;  4MDT A;  5DRR A;  2VES A;  4FW7 A;  5DRO A;  4IS9 A;  3UHM A;  1P42 A;  4LCF A;  1YHC A;  2IER A;  2IES A;  3PS1 A;  5DRQ A;  4U3B A;  2J65 A;  3PS3 A;  4FW6 A; 
#chains in the Genus database with same CATH topology
 4LOM A;  2R3V A;  2Q2E B;  5LL6 R;  4DR6 I;  5K36 A;  1S16 A;  4Z7Y A;  2PO1 B;  4U3D A;  2UUC E;  2O3Z A;  2WP8 B;  2A2C A;  5IT9 Q;  2UU9 E;  3B8H A;  5DRO A;  3H1C A;  1Z5A A;  4DV0 I;  3JAM Q;  5C0X B;  1NZ0 A;  4URL A;  2V2Q A;  4U3B A;  3PS1 A;  4DR6 E;  2BM0 A;  3P3G A;  1E3H A;  1ZM3 A;  4JI8 I;  3PRY A;  4AQY I;  4LFC I;  2JE6 A;  2DEJ A;  4P52 A;  4J3D A;  2HFS A;  4JG4 A;  2EFG A;  2JT2 A;  5DNX A;  4KHP I;  4DV0 E;  3QT8 A;  4X64 I;  1UDO A;  3T1Y I;  2JEB A;  4IZJ D;  4DR1 I;  4DV5 I;  2HHH I;  4JI0 I;  4IFD F;  1Z5B A;  4OO1 D;  3ZZU A;  4ZVI A;  4JI8 E;  4AQY E;  4LFA I;  4WUC A;  1XNQ I;  4FW6 A;  4YHH E;  4IZJ A;  2O1U A;  3PS2 A;  4KHP E;  4X64 E;  4WUB A;  4JI7 E;  4OO1 A;  4DR5 I;  2VQF I;  3T1Y E;  5K36 C;  2HHH E;  4DR1 E;  4DV5 E;  1EI1 A;  3V5R A;  4JI0 E;  5FWK A;  3U1K A;  4FW5 A;  2HFU A;  1HNX I;  4DXL A;  3J7A M;  2ZIT A;  2NN6 E;  4B3S I;  4MDT A;  4FW7 A;  4AIM A;  2C37 B;  4BA1 A;  4LFA E;  1XNQ E;  2V2Z A;  5EL9 A;  4LCF A;  1Z0G A;  5C0X E;  3ZM7 A;  1R6M A;  2WW4 A;  4MU0 A;  4DR5 E;  4NBQ A;  5EKW A;  3P3E A;  2Z5B A;  3U1Y A;  1KIJ A;  1PVG A;  2O1T A;  4DV3 I;  1IBK I;  4HY1 A;  1Y6Z A;  2JE6 B;  5GME A;  4DV4 E;  2Z5C A;  1ZXN A;  1N33 I;  4Z7C A;  5A2Q Q;  4FWH A;  4HAC A;  2ZM6 I;  5BR8 I;  2BA0 G;  4DV3 E;  1IBK E;  3PYE A;  4OO1 C;  5ELW A;  5FLX Q;  1NHJ A;  4LF6 I;  4IZJ B;  2BR2 A;  4GKK I;  4IFD B;  2VES A;  1KVK A;  4HYM A;  2PNZ A;  5JEA D;  2X36 A;  2ZM6 E;  5BR8 E;  2IES A;  5K36 D;  2CG9 A;  4MU3 A;  3PS3 A;  1H72 C;  4M1K A;  4BA1 B;  2JEA A;  3ZZT A;  2PNM A;  5JEA A;  3NZK A;  4PU9 A;  4LF6 E;  1UDS A;  2NPF A;  1N0V C;  4GKK E;  2WNR B;  1EA6 A;  4FW9 A;  4X66 I;  3CDJ A;  3B78 A;  4DV7 I;  1N32 I;  2OI2 A;  1RHY A;  1ELO A;  4JI5 I;  4NXN I;  1UDQ A;  3GME A;  4IS9 A;  4B3M I;  4OX9 I;  3CDI A;  3HJC A;  3M7N D;  4DV1 E;  4MYU A;  2J65 A;  2O1W A;  4DPY A;  4OKG A;  4X62 I;  2UXC I;  4UT4 A;  4BA2 A;  3V2U C;  4MYT A;  2HKE A;  4DUZ I;  4JYA I;  4X66 E;  4DPT A;  3F0N A;  2Z5C B;  4DV7 E;  4AM3 A;  1N32 E;  4YY3 I;  2C38 A;  4YHH I;  4JI5 E;  2GO4 A;  4JI6 I;  4NXN E;  4HAC B;  4B3M E;  4OX9 E;  5LMN I;  1Z0B A;  3PYG A;  5GMD A;  1NHH A;  5LMU E;  3GCM A;  4IFD E;  4JI7 I;  1YH8 A;  3P06 A;  2A2D A;  1HNW E;  4DV6 I;  1U2R A;  4X62 E;  2UXC E;  2C39 B;  1P42 A;  2R42 A;  4LF9 I;  1DAR A;  1Z5C A;  4OO1 F;  4DUZ E;  4B3T I;  4JYA E;  2BR2 B;  1H7U A;  4YY3 E;  3J80 C;  5JEA C;  2UXB I;  4JI6 E;  1ZM2 A;  2GQ0 A;  3K85 A;  5LMN E;  4N3O A;  4LFB I;  2UUB I;  3WU4 A;  4DR3 E;  1XHK A;  3P3C A;  4JI4 I;  2PO2 B;  1S4E A;  4IZK A;  4DV6 E;  1QZR A;  4LF9 E;  4B3T E;  4AID A;  1XMO I;  1HNZ I;  1E3P A;  4JI1 I;  5K36 B;  1Y60 A;  2UXB E;  2F4V I;  4LFB E;  2UUB E;  4JI2 E;  4ISA A;  4JI4 E;  3OTO I;  4DV4 I;  2UUA E;  4R1F A;  2CZ9 A;  3PYD A;  1ZM9 A;  3M85 D;  1XMO E;  4DUY I;  1HNZ E;  4JI1 E;  4BA2 B;  1Y4S A;  3L7Z A;  4DPW A;  2F4V E;  2NN6 D;  2BA1 D;  1A6F A;  3OTO E;  2Z5E A;  4DV2 E;  2PO1 A;  4QNK A;  1H73 A;  2WP8 A;  3Q1Q A;  4DUY E;  2JEB B;  1NHI A;  4WUD A;  3KRN A;  2NN6 A;  4K0K E;  3P76 A;  1Z0E A;  2GO3 A;  5C0X A;  1FJG E;  2O1V A;  2BM1 A;  3WU3 A;  4LCH A;  1IBL I;  1WUU A;  5JEA F;  1VI7 A;  4FWD A;  1XNR I;  4XTJ A;  4OO1 B;  1USU A;  3UHM A;  2E1R A;  1YHC A;  1KTV A;  4HXZ A;  4IZK B;  4LF7 I;  3WU5 A;  1FNM A;  1FKA E;  5K36 F;  2PO0 A;  1D6T A;  2VF3 A;  1ZM4 A;  4DR7 I;  2HK3 A;  2DEI A;  5IT9 C;  3LTO A;  4MQY A;  4DV1 I;  1HR0 I;  4DR2 E;  1MG7 A;  4DR4 I;  3CWV A;  4FWG A;  1IBL E;  4DU8 A;  4LPF A;  4LCG A;  1I94 E;  1XNR E;  3GLL A;  4USM A;  2IOP A;  3GON A;  1N36 I;  1OYR A;  4LF7 E;  3J7A G;  2ZBK B;  4LF4 I;  1OYS A;  4DR7 E;  2Z5B B;  1HK7 A;  3QT5 A;  3QT6 A;  1OJ4 A;  1XMQ I;  5DRQ A;  5LMU I;  1IBM I;  1HR0 E;  4JI3 I;  4DR4 E;  1HNW I;  3L7Z B;  2C37 A;  2NN6 C;  1RR9 A;  2J7K A;  3T1H I;  1N36 E;  1FWK A;  2V2V A;  1Z0W A;  4LF4 E;  1Z0T A;  5C0X C;  4FW3 A;  2HK2 A;  2NN6 B;  1XMQ E;  1IBM E;  4JI3 E;  4LF8 I;  4DR3 I;  4OO1 E;  2AJ4 A;  2IER A;  3J81 C;  3T1H E;  4JV5 I;  1MU5 A;  2CGE A;  2PNZ B;  3B82 A;  1MX0 A;  1XXE A;  1J5E I;  1K47 A;  2X7I A;  3Q6N A;  3M6A A;  4NXM I;  3K17 A;  2PO0 B;  4LF8 E;  4JI2 I;  1BKN A;  3K1J A;  1B63 A;  4P7A A;  1UDN A;  2UUA I;  2JEA B;  5JEA B;  3H4L A;  3M7N G;  4JV5 E;  4IFD D;  4LF5 I;  4LFC E;  1J5E E;  3HKM A;  5DNL A;  1Y4U A;  4NXM E;  2PNL A;  4DPU A;  4IFD A;  4X65 I;  3J81 Q;  4DV2 I;  2V34 A;  4QNJ A;  3Q6M A;  5IWA I;  2BA0 D;  2E5L I;  1OYP A;  3J80 Q;  1ZXM A;  1KKH A;  1H74 A;  2BV3 A;  1N34 I;  4LF5 E;  4K0K I;  4FW4 A;  5A2Q C;  4UTG A;  4B3R I;  4GKJ I;  1PKP A;  3PYF A;  2NN6 F;  4KQV A;  4EMD A;  2UXD I;  2C38 B;  1FJG I;  4X65 E;  2WNR A;  2VQF E;  3ZZ0 A;  5C0X F;  5IWA E;  5FLX C;  5C0X D;  3QT7 A;  4RPF A;  2E5L E;  1HNX E;  3WU6 A;  4DPX A;  2HKJ A;  1N34 E;  1UEK A;  4B3S E;  5DRP A;  1Z0C A;  1FI4 A;  3LPS A;  1VIS A;  4B3R E;  1Y5Y A;  4GKJ E;  4MU4 A;  3B4T A;  4ED4 A;  1FWL A;  2IOQ A;  4USK A;  5JEA E;  1H7S A;  2UXD E;  4DR2 I;  5DRR A;  2GS8 A;  3D4J A;  1I94 I;  5K36 E;  1R6L A;  2V8P A;  3LNU A;  3HUL A;  1Z0V A;  2LJP A;  3ZKD A;  1B62 A;  1N0U A;  1USV A;  4DU7 A;  4I3H A;  3ZKB A;  3M85 G;  4IFD C;  2VQE I;  4GQU A;  3DD6 A;  2C39 A;  3JAM C;  4OZE A;  2F1D A;  2BA1 G;  1Z59 A;  1N33 E;  4PRX A;  4PRV A;  2CVE A;  4MU1 A;  2AE8 A;  5L3J A;  2UUC I;  2XEX A;  2VQE E;  2UU9 I;  4FN5 A;  2PO2 A;  1RRE A;  1PIE A; 
#chains in the Genus database with same CATH homology
 4OKG A;  4ISA A;  3P3G A;  3NZK A;  3PS2 A;  1XXE A;  4MQY A;  3P3E A;  3P76 A;  4J3D A;  3U1Y A;  5DRP A;  3P3C A;  4LCG A;  2GO4 A;  2GO3 A;  4U3D A;  2JT2 A;  2O3Z A;  4FW5 A;  4OZE A;  4FW3 A;  4LCH A;  4FW4 A;  1YH8 A;  4MDT A;  5DRR A;  2VES A;  4FW7 A;  5DRO A;  4IS9 A;  3UHM A;  1P42 A;  4LCF A;  1YHC A;  2IER A;  2IES A;  3PS1 A;  5DRQ A;  4U3B A;  2J65 A;  3PS3 A;  4FW6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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