2GO4A

Crystal structure of aquifex aeolicus lpxc complexed with tu-514
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
266
structure length
266
Chain Sequence
b'GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
molecule tags Hydrolase
source organism Aquifex aeolicus
publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
total genus 88
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go4A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go4A02
5DROA 3UHMA 4FW5A 4FW3A 1YHCA 3P3GA 4LCGA 4FW6A 1P42A 2JT2A 3P76A 2J65A 4FW7A 2GO3A 1XXEA 2VESA 4FW4A 5DRRA 4LCFA 2GO4A 4IS9A 4ISAA 3U1YA 4OKGA 4U3BA 3P3CA 3P3EA 4J3DA 4MDTA 3NZKA 2O3ZA 3PS3A 4OZEA 1YH8A 5DRQA 4U3DA 2IESA 4LCHA 4MQYA 3PS1A 3PS2A 2IERA 5DRPA
chains in the Genus database with same CATH superfamily
2NN6D 4LF9E 3P3GA 4OO1C 5C0XE 4DV0I 2Z5BA 4DV2I 5EL9A 4BA2B 1VISA 2Z5CA 1IBLE 1UEKA 2WW4A 1IBME 4AQYE 4DU7A 3M85G 2HK3A 1E3HA 4K0KI 5JEAA 2JEAB 3WU5A 5FLXQ 4DUZE 1XMOI 2UU9I 4DV5E 4LF7E 2A2CA 3QT5A 1RR9A 1IBMI 4JI5E 3K1JA 4LCGA 1IBKI 1ZM3A 5GMDA 4FN5A 4B3RE 1UDNA 4QNJA 4R1FA 1XNQI 4LCFA 4DR3E 2X36A 1ZM2A 3U1YA 3HULA 2WP8A 3HKMA 3J81Q 3LNUA 2PO0B 4OO1F 1YH8A 1OJ4A 3JAMC 5ELWA 4DR7I 2R42A 1PKPA 4LCHA 1HNZE 2NN6B 2UU9E 5C0XA 1N33E 1FKAE 2Z5CB 4X65I 3PRYA 1Z0GA 3OTOE 4JI8I 1Z0VA 1YHCA 4YY3I 5K36D 2HHHI 4BA1B 4B3ME 1HNWE 4DV4I 4FWGA 3J80C 4JI1I 1XXEA 4DR5I 5LMNI 1Z0WA 2V2QA 2ZITA 1USUA 4DV3E 4IZJD 4JI3E 4DR7E 1N36I 4KQVA 3D4JA 3P06A 1Y4UA 2WNRA 4IFDA 2ZBKB 1IBLI 2Z5BB 1J5EI 1P42A 1HNXI 4AIMA 4KHPI 4K0KE 4USKA 4DR2E 2UUCI 2PO1A 2PNZA 1ELOA 4U3BA 3P3CA 5IWAE 4WUDA 2BA0D 3PS3A 1N36E 2OI2A 4BA1A 3U1KA 5A2QC 4JI2I 2A2DA 4XTJA 4Z7YA 4UTGA 2Q2EB 2V8PA 1N34E 1FJGI 2O1WA 1N0VC 2BA0G 4LF8I 3H1CA 5BR8I 3K85A 4DV2E 3JAMQ 5C0XD 1H74A 2BA1G 1NHIA 1MX0A 1XHKA 4AQYI 1UDQA 3ZZ0A 4IFDF 3M6AA 4DV1E 5JEAE 1UDOA 3Q1QA 1N33I 3T1YE 3PYDA 4X65E 1Y60A 1XMOE 3UHMA 4JI8E 4HACB 2JT2A 3GONA 1QZRA 1XMQE 4X64E 1Z0BA 4N3OA 3T1HI 4YHHE 2BV3A 2CGEA 4PRVA 2HKEA 4NXME 4HYMA 4IS9A 4LF5I 2JE6A 4DV5I 3P3EA 1Z5CA 4J3DA 4DR3I 4JI6E 2UXBE 1PVGA 4X66I 2V2VA 4DV3I 2O1UA 5DRQA 4LPFA 2CVEA 1Z59A 1HR0I 2LJPA 3K17A 3WU4A 4MYTA 1XMQI 4DR6E 2UUBE 4LFCE 1HNXE 4QNKA 1I94E 2PNZB 1EI1A 1XNRI 5C0XB 4FWDA 4DPTA 1UDSA 4LF4E 5IT9Q 4ISAA 4IZKB 4HY1A 4I3HA 2UXCI 2PO1B 4LFBE 3LPSA 4HACA 2C38A 4OO1E 1WUUA 2NN6E 4MQYA 1XNRE 3V5RA 5FLXC 1FWKA 5LMNE 4ED4A 5BR8E 3QT8A 2AJ4A 1FWLA 3B78A 2O1TA 4IFDE 2HFUA 3WU6A 4JI0I 1HK7A 2DEIA 4USMA 2GQ0A 4JI3I 2WNRB 2DEJA 2BR2B 3PYEA 3Q6MA 3J80Q 3L7ZA 2J7KA 1J5EE 5IT9C 2O3ZA 1S4EA 4WUCA 3V2UC 4DV7E 3B4TA 4M1KA 4JI2E 1XNQE 1B63A 1OYPA 4NBQA 4FW6A 5DNXA 2WP8B 1NHHA 1B62A 4DPWA 4DR4I 4NXMI 3CDJA 4IZJB 2NN6A 5LL6R 4RPFA 1N34I 3NZKA 1Z0EA 1H73A 4GQUA 1KKHA 4X66E 4Z7CA 1KTVA 4AIDA 3B8HA 4LFAI 4MU3A 1IBKE 2NN6C 3J7AG 1Z0CA 1HR0E 2PO2A 5DROA 4DR5E 4X62E 4HXZA 1N0UA 2JEBB 4B3TE 4LF7I 4OX9E 2J65A 3LTOA 1Y4SA 3H4LA 5C0XF 3ZZTA 4LF9I 3B82A 4MU0A 2E5LE 2C37A 2PO0A 5C0XC 4DPYA 4B3RI 3T1YI 4MDTA 4X62I 4DV6I 4IZKA 2HK2A 4B3TI 2C39B 3GMEA 2HKJA 4DU8A 5A2QQ 2BM1A 2IESA 3OTOI 2C38B 4KHPE 4YY3E 2IERA 5DRPA 2NPFA 1OYSA 1H72C 4LF5E 2CG9A 3PYFA 1NHJA 4P52A 4DUYI 3M7NG 5IWAI 4JI0E 2BM0A 4ZVIA 2HHHE 1K47A 5FWKA 1HNWI 3ZZUA 2F4VI 2X7IA 4OZEA 4OO1B 4NXNE 2UUBI 4U3DA 1MU5A 4EMDA 2IOQA 5JEAF 2UXCE 3PS2A 4LF8E 4GKKE 4JI7E 1D6TA 2F1DA 4DPUA 4LF4I 4OO1D 3KRNA 1USVA 4FW5A 4DR2I 2UUCE 1ZXNA 2VQFI 3F0NA 3CWVA 1E3PA 1RREA 4B3SI 3Q6NA 2V2ZA 1ZXMA 4DPXA 2F4VE 1ZM9A 2VQEI 4IFDD 4P7AA 3ZKDA 1N32I 4FWHA 4JI1E 1EA6A 4GKJE 3GCMA 4AM3A 1FI4A 1VI7A 2VF3A 4B3SE 1U2RA 2PO2B 2Z5EA 5L3JA 4DV0E 4MU1A 4DV7I 2VQEE 5GMEA 5K36B 1FNMA 4DUZI 2GO3A 2GS8A 4DV6E 2VESA 4OO1A 1RHYA 4OKGA 3J81C 3J7AM 4DV1I 5LMUI 2C37B 2NN6F 4MYUA 5JEAC 1Y6ZA 2UUAE 3ZKBA 3P76A 3HJCA 4JV5I 1KIJA 2PNMA 1HNZI 2JE6B 2CZ9A 1FJGE 1DARA 4FW4A 5DRRA 4LFBI 4LF6I 4X64I 2EFGA 4YHHI 4UT4A 2JEBA 4URLA 3ZM7A 2E5LI 4PRXA 1PIEA 1S16A 2IOPA 2UUAI 2E1RA 2R3VA 4JI4I 5JEAB 5K36E 1MG7A 1Z5AA 1Z5BA 4IFDC 2VQFE 3GLLA 2ZM6E 4DR1I 4LF6E 4JI5I 4GKKI 2UXDI 4JI7I 4FW3A 4WUBA 2C39A 1Y5YA 5JEAD 3L7ZB 3QT6A 3PYGA 3CDIA 4JI4E 1OYRA 4DR6I 4GKJI 3WU3A 4LFCI 5EKWA 5K36C 1H7SA 2ZM6I 4DR1E 2UXDE 4LOMA 4BA2A 3T1HE 4PU9A 4MU4A 3M7ND 1KVKA 2HFSA 4JYAE 4DUYE 1ZM4A 4FW9A 2V34A 4NXNI 4JI6I 2UXBI 1NZ0A 2XEXA 3DD6A 2JEAA 4DV4E 1Z0TA 4DR4E 2BA1D 4FW7A 1A6FA 2PNLA 4IZJA 1H7UA 5K36F 2O1VA 4JG4A 4DXLA 2GO4A 4B3MI 1R6LA 4LFAE 5K36A 5DNLA 1I94I 2AE8A 2BR2A 1R6MA 4JYAI 5LMUE 1N32E 4OX9I 3PS1A 4IFDB 3M85D 4JV5E 3QT7A 1BKNA
chains in the Genus database with same CATH topology
5DROA 3UHMA 4FW5A 4FW3A 1YHCA 3P3GA 4LCGA 4FW6A 1P42A 2JT2A 3P76A 2J65A 4FW7A 2GO3A 1XXEA 2VESA 4FW4A 5DRRA 4LCFA 2GO4A 4IS9A 4ISAA 3U1YA 4OKGA 4U3BA 3P3CA 3P3EA 4J3DA 4MDTA 3NZKA 2O3ZA 3PS3A 4OZEA 1YH8A 5DRQA 4U3DA 2IESA 4LCHA 4MQYA 3PS1A 3PS2A 2IERA 5DRPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DRO A;  3UHM A;  4FW5 A;  4FW3 A;  1YHC A;  3P3G A;  4LCG A;  4FW6 A;  1P42 A;  2JT2 A;  3P76 A;  2J65 A;  4FW7 A;  2GO3 A;  1XXE A;  2VES A;  4FW4 A;  5DRR A;  4LCF A;  2GO4 A;  4IS9 A;  4ISA A;  3U1Y A;  4OKG A;  4U3B A;  3P3C A;  3P3E A;  4J3D A;  4MDT A;  3NZK A;  2O3Z A;  3PS3 A;  4OZE A;  1YH8 A;  5DRQ A;  4U3D A;  2IES A;  4LCH A;  4MQY A;  3PS1 A;  3PS2 A;  2IER A;  5DRP A; 
#chains in the Genus database with same CATH topology
 2NN6 D;  4LF9 E;  3P3G A;  4OO1 C;  5C0X E;  4DV0 I;  2Z5B A;  4DV2 I;  5EL9 A;  4BA2 B;  1VIS A;  2Z5C A;  1IBL E;  1UEK A;  2WW4 A;  1IBM E;  4AQY E;  4DU7 A;  3M85 G;  2HK3 A;  1E3H A;  4K0K I;  5JEA A;  2JEA B;  3WU5 A;  5FLX Q;  4DUZ E;  1XMO I;  2UU9 I;  4DV5 E;  4LF7 E;  2A2C A;  3QT5 A;  1RR9 A;  1IBM I;  4JI5 E;  3K1J A;  4LCG A;  1IBK I;  1ZM3 A;  5GMD A;  4FN5 A;  4B3R E;  1UDN A;  4QNJ A;  4R1F A;  1XNQ I;  4LCF A;  4DR3 E;  2X36 A;  1ZM2 A;  3U1Y A;  3HUL A;  2WP8 A;  3HKM A;  3J81 Q;  3LNU A;  2PO0 B;  4OO1 F;  1YH8 A;  1OJ4 A;  3JAM C;  5ELW A;  4DR7 I;  2R42 A;  1PKP A;  4LCH A;  1HNZ E;  2NN6 B;  2UU9 E;  5C0X A;  1N33 E;  1FKA E;  2Z5C B;  4X65 I;  3PRY A;  1Z0G A;  3OTO E;  4JI8 I;  1Z0V A;  1YHC A;  4YY3 I;  5K36 D;  2HHH I;  4BA1 B;  4B3M E;  1HNW E;  4DV4 I;  4FWG A;  3J80 C;  4JI1 I;  1XXE A;  4DR5 I;  5LMN I;  1Z0W A;  2V2Q A;  2ZIT A;  1USU A;  4DV3 E;  4IZJ D;  4JI3 E;  4DR7 E;  1N36 I;  4KQV A;  3D4J A;  3P06 A;  1Y4U A;  2WNR A;  4IFD A;  2ZBK B;  1IBL I;  2Z5B B;  1J5E I;  1P42 A;  1HNX I;  4AIM A;  4KHP I;  4K0K E;  4USK A;  4DR2 E;  2UUC I;  2PO1 A;  2PNZ A;  1ELO A;  4U3B A;  3P3C A;  5IWA E;  4WUD A;  2BA0 D;  3PS3 A;  1N36 E;  2OI2 A;  4BA1 A;  3U1K A;  5A2Q C;  4JI2 I;  2A2D A;  4XTJ A;  4Z7Y A;  4UTG A;  2Q2E B;  2V8P A;  1N34 E;  1FJG I;  2O1W A;  1N0V C;  2BA0 G;  4LF8 I;  3H1C A;  5BR8 I;  3K85 A;  4DV2 E;  3JAM Q;  5C0X D;  1H74 A;  2BA1 G;  1NHI A;  1MX0 A;  1XHK A;  4AQY I;  1UDQ A;  3ZZ0 A;  4IFD F;  3M6A A;  4DV1 E;  5JEA E;  1UDO A;  3Q1Q A;  1N33 I;  3T1Y E;  3PYD A;  4X65 E;  1Y60 A;  1XMO E;  3UHM A;  4JI8 E;  4HAC B;  2JT2 A;  3GON A;  1QZR A;  1XMQ E;  4X64 E;  1Z0B A;  4N3O A;  3T1H I;  4YHH E;  2BV3 A;  2CGE A;  4PRV A;  2HKE A;  4NXM E;  4HYM A;  4IS9 A;  4LF5 I;  2JE6 A;  4DV5 I;  3P3E A;  1Z5C A;  4J3D A;  4DR3 I;  4JI6 E;  2UXB E;  1PVG A;  4X66 I;  2V2V A;  4DV3 I;  2O1U A;  5DRQ A;  4LPF A;  2CVE A;  1Z59 A;  1HR0 I;  2LJP A;  3K17 A;  3WU4 A;  4MYT A;  1XMQ I;  4DR6 E;  2UUB E;  4LFC E;  1HNX E;  4QNK A;  1I94 E;  2PNZ B;  1EI1 A;  1XNR I;  5C0X B;  4FWD A;  4DPT A;  1UDS A;  4LF4 E;  5IT9 Q;  4ISA A;  4IZK B;  4HY1 A;  4I3H A;  2UXC I;  2PO1 B;  4LFB E;  3LPS A;  4HAC A;  2C38 A;  4OO1 E;  1WUU A;  2NN6 E;  4MQY A;  1XNR E;  3V5R A;  5FLX C;  1FWK A;  5LMN E;  4ED4 A;  5BR8 E;  3QT8 A;  2AJ4 A;  1FWL A;  3B78 A;  2O1T A;  4IFD E;  2HFU A;  3WU6 A;  4JI0 I;  1HK7 A;  2DEI A;  4USM A;  2GQ0 A;  4JI3 I;  2WNR B;  2DEJ A;  2BR2 B;  3PYE A;  3Q6M A;  3J80 Q;  3L7Z A;  2J7K A;  1J5E E;  5IT9 C;  2O3Z A;  1S4E A;  4WUC A;  3V2U C;  4DV7 E;  3B4T A;  4M1K A;  4JI2 E;  1XNQ E;  1B63 A;  1OYP A;  4NBQ A;  4FW6 A;  5DNX A;  2WP8 B;  1NHH A;  1B62 A;  4DPW A;  4DR4 I;  4NXM I;  3CDJ A;  4IZJ B;  2NN6 A;  5LL6 R;  4RPF A;  1N34 I;  3NZK A;  1Z0E A;  1H73 A;  4GQU A;  1KKH A;  4X66 E;  4Z7C A;  1KTV A;  4AID A;  3B8H A;  4LFA I;  4MU3 A;  1IBK E;  2NN6 C;  3J7A G;  1Z0C A;  1HR0 E;  2PO2 A;  5DRO A;  4DR5 E;  4X62 E;  4HXZ A;  1N0U A;  2JEB B;  4B3T E;  4LF7 I;  4OX9 E;  2J65 A;  3LTO A;  1Y4S A;  3H4L A;  5C0X F;  3ZZT A;  4LF9 I;  3B82 A;  4MU0 A;  2E5L E;  2C37 A;  2PO0 A;  5C0X C;  4DPY A;  4B3R I;  3T1Y I;  4MDT A;  4X62 I;  4DV6 I;  4IZK A;  2HK2 A;  4B3T I;  2C39 B;  3GME A;  2HKJ A;  4DU8 A;  5A2Q Q;  2BM1 A;  2IES A;  3OTO I;  2C38 B;  4KHP E;  4YY3 E;  2IER A;  5DRP A;  2NPF A;  1OYS A;  1H72 C;  4LF5 E;  2CG9 A;  3PYF A;  1NHJ A;  4P52 A;  4DUY I;  3M7N G;  5IWA I;  4JI0 E;  2BM0 A;  4ZVI A;  2HHH E;  1K47 A;  5FWK A;  1HNW I;  3ZZU A;  2F4V I;  2X7I A;  4OZE A;  4OO1 B;  4NXN E;  2UUB I;  4U3D A;  1MU5 A;  4EMD A;  2IOQ A;  5JEA F;  2UXC E;  3PS2 A;  4LF8 E;  4GKK E;  4JI7 E;  1D6T A;  2F1D A;  4DPU A;  4LF4 I;  4OO1 D;  3KRN A;  1USV A;  4FW5 A;  4DR2 I;  2UUC E;  1ZXN A;  2VQF I;  3F0N A;  3CWV A;  1E3P A;  1RRE A;  4B3S I;  3Q6N A;  2V2Z A;  1ZXM A;  4DPX A;  2F4V E;  1ZM9 A;  2VQE I;  4IFD D;  4P7A A;  3ZKD A;  1N32 I;  4FWH A;  4JI1 E;  1EA6 A;  4GKJ E;  3GCM A;  4AM3 A;  1FI4 A;  1VI7 A;  2VF3 A;  4B3S E;  1U2R A;  2PO2 B;  2Z5E A;  5L3J A;  4DV0 E;  4MU1 A;  4DV7 I;  2VQE E;  5GME A;  5K36 B;  1FNM A;  4DUZ I;  2GO3 A;  2GS8 A;  4DV6 E;  2VES A;  4OO1 A;  1RHY A;  4OKG A;  3J81 C;  3J7A M;  4DV1 I;  5LMU I;  2C37 B;  2NN6 F;  4MYU A;  5JEA C;  1Y6Z A;  2UUA E;  3ZKB A;  3P76 A;  3HJC A;  4JV5 I;  1KIJ A;  2PNM A;  1HNZ I;  2JE6 B;  2CZ9 A;  1FJG E;  1DAR A;  4FW4 A;  5DRR A;  4LFB I;  4LF6 I;  4X64 I;  2EFG A;  4YHH I;  4UT4 A;  2JEB A;  4URL A;  3ZM7 A;  2E5L I;  4PRX A;  1PIE A;  1S16 A;  2IOP A;  2UUA I;  2E1R A;  2R3V A;  4JI4 I;  5JEA B;  5K36 E;  1MG7 A;  1Z5A A;  1Z5B A;  4IFD C;  2VQF E;  3GLL A;  2ZM6 E;  4DR1 I;  4LF6 E;  4JI5 I;  4GKK I;  2UXD I;  4JI7 I;  4FW3 A;  4WUB A;  2C39 A;  1Y5Y A;  5JEA D;  3L7Z B;  3QT6 A;  3PYG A;  3CDI A;  4JI4 E;  1OYR A;  4DR6 I;  4GKJ I;  3WU3 A;  4LFC I;  5EKW A;  5K36 C;  1H7S A;  2ZM6 I;  4DR1 E;  2UXD E;  4LOM A;  4BA2 A;  3T1H E;  4PU9 A;  4MU4 A;  3M7N D;  1KVK A;  2HFS A;  4JYA E;  4DUY E;  1ZM4 A;  4FW9 A;  2V34 A;  4NXN I;  4JI6 I;  2UXB I;  1NZ0 A;  2XEX A;  3DD6 A;  2JEA A;  4DV4 E;  1Z0T A;  4DR4 E;  2BA1 D;  4FW7 A;  1A6F A;  2PNL A;  4IZJ A;  1H7U A;  5K36 F;  2O1V A;  4JG4 A;  4DXL A;  2GO4 A;  4B3M I;  1R6L A;  4LFA E;  5K36 A;  5DNL A;  1I94 I;  2AE8 A;  2BR2 A;  1R6M A;  4JYA I;  5LMU E;  1N32 E;  4OX9 I;  3PS1 A;  4IFD B;  3M85 D;  4JV5 E;  3QT7 A;  1BKN A; 
#chains in the Genus database with same CATH homology
 5DRO A;  3UHM A;  4FW5 A;  4FW3 A;  1YHC A;  3P3G A;  4LCG A;  4FW6 A;  1P42 A;  2JT2 A;  3P76 A;  2J65 A;  4FW7 A;  2GO3 A;  1XXE A;  2VES A;  4FW4 A;  5DRR A;  4LCF A;  2GO4 A;  4IS9 A;  4ISA A;  3U1Y A;  4OKG A;  4U3B A;  3P3C A;  3P3E A;  4J3D A;  4MDT A;  3NZK A;  2O3Z A;  3PS3 A;  4OZE A;  1YH8 A;  5DRQ A;  4U3D A;  2IES A;  4LCH A;  4MQY A;  3PS1 A;  3PS2 A;  2IER A;  5DRP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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