2GO4A

Crystal structure of aquifex aeolicus lpxc complexed with tu-514
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
source organism Aquifex aeolicus
total genus 88
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go4A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go4A02
2JT2A 4OZEA 4ISAA 5DRQA 4FW7A 3P3GA 2IERA 3P76A 4LCHA 3UHMA 3PS3A 3P3CA 2GO3A 5DRRA 3U1YA 2J65A 1XXEA 1YHCA 4OKGA 1YH8A 3NZKA 3PS1A 3PS2A 4LCGA 2O3ZA 4FW6A 4MDTA 2VESA 4MQYA 4J3DA 4IS9A 4LCFA 4U3BA 5DROA 4FW3A 4U3DA 4FW5A 2IESA 2GO4A 5DRPA 4FW4A 3P3EA 1P42A
chains in the Genus database with same CATH superfamily
4OZEA 4X64I 3M7ND 2WP8B 4OKGA 5C0XD 2IOQA 3PYFA 2C37A 4DR7I 4LFAE 2Z5EA 2VQEI 1FWKA 1OYSA 1IBMI 4OO1F 2PO1B 2VQFI 1Y6ZA 4DU7A 3QT6A 4U3BA 2PO0A 4FW5A 4DR3E 5FWKA 2PNZB 2BA0D 1J5EI 2A2CA 3P3EA 4PU9A 4DV4I 4LFCE 5DNXA 1Z0CA 1N34E 4JI4I 2BR2B 4FWGA 4X62E 2O1TA 1N32E 3P06A 4LF9E 4LCGA 4NXNI 4DV2I 3T1HE 4USMA 3GMEA 2O1VA 1VI7A 1FWLA 2WNRB 2UXBE 2BV3A 1HNZI 4FWDA 4U3DA 3JAMQ 1UDQA 4K0KI 3HKMA 4NBQA 4JI6E 2HFSA 4B3ME 4DV0E 5JEAB 4FW7A 1UDNA 1ZXNA 2GO3A 3P3CA 5IWAI 2IOPA 2Z5BB 2PO2B 3PS1A 4LF8E 4HACA 5K36B 3J80C 2VESA 3CDIA 4R1FA 3GCMA 1N33I 1XMQI 4JI1I 3J81Q 2UXDE 4B3SE 4QNJA 4FWHA 4ED4A 4JI2E 4PRVA 4N3OA 4FW4A 1ZM3A 2DEJA 1H72C 1H73A 4DV6I 2UXCE 2O1WA 3P76A 5K36C 4JV5E 4JI3I 3CDJA 4DV5E 2JEAA 4OO1D 2AJ4A 3PS2A 1I94I 4DV7I 1BKNA 4MU1A 4LFBE 5K36E 4IFDA 4JI5E 2CG9A 1HNWI 3B82A 4BA2A 2PO0B 4JI8I 3M6AA 4USKA 4WUBA 4DR5E 2BA1D 3ZKDA 3ZZTA 5BR8I 4RPFA 3UHMA 3PYDA 5A2QC 1IBKE 1Y60A 1Z59A 1RREA 3WU3A 5K36F 1N36I 3T1YE 3F0NA 4IZJD 1Y4SA 3M7NG 3PYGA 1XHKA 2BM0A 4DR2E 4AQYE 4B3RI 2LJPA 2HHHE 2AE8A 2CZ9A 1HK7A 2JEBA 1P42A 2UUCE 4LFCI 4XTJA 4DU8A 1Y5YA 4YHHE 2V8PA 4MU3A 4X62I 1N0VC 1YHCA 5ELWA 1RR9A 4LF9I 3NZKA 2UUBE 2BA0G 4HACB 3GONA 1Y4UA 3PYEA 4YY3I 2ZM6E 4IS9A 4LCFA 2UXBI 4DV1E 1HNXE 4FW9A 2UUAE 2WW4A 3CWVA 4P7AA 1D6TA 3Q6MA 4LF6E 4DUYI 4DV0I 4BA1A 1NHJA 1EI1A 5IT9Q 4X65E 1Z0EA 1MX0A 1FJGE 1XMOE 4LF8I 3D4JA 2ZBKB 2V2ZA 3OTOI 4GKJE 3GLLA 4MDTA 2JEAB 3K1JA 1S16A 4LF5E 4JI7E 4DPXA 4LF7E 4OX9I 5LMNE 4GKKI 1EA6A 2UXDI 3QT7A 4NXME 4FW3A 4B3SI 2F4VE 4JYAI 2NN6C 4IFDB 2E1RA 4JI2I 1FNMA 2GS8A 4BA2B 5FLXQ 5JEAD 3B4TA 3ZM7A 2J7KA 2UXCI 3L7ZA 1XNQE 1MG7A 3M85D 4Z7YA 4DV5I 5K36D 2CVEA 3B8HA 2HKJA 2NN6E 4KHPE 3KRNA 3LPSA 4B3TI 1MU5A 1IBME 4LFBI 4IZJA 1XNRE 5C0XE 4LOMA 2E5LE 4IFDC 1FI4A 4JI5I 4DV3E 4KQVA 4DR1I 1OYRA 2ZITA 4LF4I 4JI0E 2NN6A 2EFGA 4URLA 2C39A 5EKWA 4MYUA 4MU0A 4IZKA 2OI2A 4IFDE 3HJCA 2JEBB 4HXZA 3V5RA 4JI4E 3DD6A 2JE6A 5C0XA 1NHIA 1USUA 2A2DA 2PNLA 5DNLA 4WUCA 3ZZUA 1Z0WA 2HK2A 1HR0E 2R3VA 4DUZI 2PNMA 4AIDA 4X66I 3T1YI 2BA1G 1H74A 1DARA 4DPYA 4AQYI 3WU4A 3K17A 1KTVA 5LMUE 2UU9E 4IFDF 2UUCI 1K47A 1ZXMA 2VF3A 3J7AM 2Z5CA 4YHHI 2V2VA 4BA1B 4DPWA 3QT5A 1R6LA 2UUBI 4LFAI 1N33E 4DR4E 1XMQE 3HULA 4DV1I 5GMDA 1VISA 2X7IA 5LL6R 1HNXI 2UUAI 1PIEA 4DXLA 4DR3I 4AIMA 3JAMC 4LF6I 2HKEA 1ZM9A 5FLXC 2X36A 3WU6A 1RHYA 4X65I 5GMEA 2NPFA 1N34I 5DRRA 4OO1C 1FJGI 1XXEA 3L7ZB 1N32I 4GKJI 3LNUA 4DR6E 4LPFA 4DV7E 1USVA 4MQYA 3T1HI 4LF7I 1HNWE 1IBLE 4OO1E 4IZJB 4AM3A 3J81C 1PVGA 2IESA 1Z5AA 1R6MA 4JI6I 1U2RA 5DRPA 4B3MI 1Z5CA 1Z5BA 4GQUA 4ZVIA 1QZRA 2NN6B 1XNQI 1N0UA 1Z0BA 5BR8E 2C39B 2IERA 1OYPA 1OJ4A 4IZKB 4EMDA 4KHPI 4OO1A 4Z7CA 4FW6A 2JE6B 5C0XB 1N36E 1WUUA 1XNRI 2E5LI 1KIJA 3U1KA 4J3DA 4DV3I 5DROA 4IFDD 4DPUA 3M85G 4B3RE 2C38A 2HFUA 4JI0I 3Q6NA 1S4EA 1UEKA 4X64E 1KKHA 4ISAA 5A2QQ 5C0XC 3PS3A 4JV5I 2O1UA 1Z0GA 3U1YA 4P52A 2Z5CB 1Z0VA 4DPTA 2O3ZA 4DR7E 1H7UA 3ZKBA 1HR0I 3H4LA 4HY1A 2VQEE 2F1DA 4YY3E 4UTGA 3ZZ0A 2VQFE 4JG4A 3K85A 4WUDA 5LMUI 2UU9I 4DUYE 1J5EE 4M1KA 2WP8A 3WU5A 2V34A 4DV4E 4DR5I 1A6FA 2V2QA 2NN6F 3LTOA 2J65A 1E3PA 1IBKI 3OTOE 2PO1A 4NXNE 4DV2E 2GQ0A 5C0XF 4DR4I 1NZ0A 1FKAE 4PRXA 1B62A 4OX9E 4GKKE 1E3HA 1ZM2A 2PNZA 1PKPA 4I3HA 1HNZE 4JYAE 4DR2I 5JEAC 4FN5A 4K0KE 2HHHI 2CGEA 2DEIA 2BR2A 1Z0TA 5DRQA 5IT9C 4UT4A 5IWAE 1YH8A 4DR6I 5JEAE 4B3TE 2R42A 2WNRA 2C37B 4OO1B 2XEXA 3J7AG 1UDSA 2ZM6I 1IBLI 4JI1E 4DR1E 3B78A 1KVKA 4LF4E 1ELOA 2Q2EB 5JEAA 2C38B 2JT2A 4DV6E 2Z5BA 2PO2A 5JEAF 3P3GA 4LCHA 5K36A 4JI3E 1XMOI 4MYTA 3J80Q 1I94E 2BM1A 4MU4A 1ZM4A 4DUZE 3QT8A 3PRYA 4X66E 4LF5I 1B63A 4JI7I 3H1CA 3V2UC 1UDOA 5LMNI 4NXMI 3Q1QA 2F4VI 4QNKA 4HYMA 5EL9A 2GO4A 1NHHA 2HK3A 5L3JA 2NN6D 4JI8E 1H7SA
chains in the Genus database with same CATH topology
2JT2A 4OZEA 4ISAA 5DRQA 4FW7A 3P3GA 2IERA 3P76A 4LCHA 3UHMA 3PS3A 3P3CA 2GO3A 5DRRA 3U1YA 2J65A 1XXEA 1YHCA 4OKGA 1YH8A 3NZKA 3PS1A 3PS2A 4LCGA 2O3ZA 4FW6A 4MDTA 2VESA 4MQYA 4J3DA 4IS9A 4LCFA 4U3BA 5DROA 4FW3A 4U3DA 4FW5A 2IESA 2GO4A 5DRPA 4FW4A 3P3EA 1P42A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JT2 A;  4OZE A;  4ISA A;  5DRQ A;  4FW7 A;  3P3G A;  2IER A;  3P76 A;  4LCH A;  3UHM A;  3PS3 A;  3P3C A;  2GO3 A;  5DRR A;  3U1Y A;  2J65 A;  1XXE A;  1YHC A;  4OKG A;  1YH8 A;  3NZK A;  3PS1 A;  3PS2 A;  4LCG A;  2O3Z A;  4FW6 A;  4MDT A;  2VES A;  4MQY A;  4J3D A;  4IS9 A;  4LCF A;  4U3B A;  5DRO A;  4FW3 A;  4U3D A;  4FW5 A;  2IES A;  2GO4 A;  5DRP A;  4FW4 A;  3P3E A;  1P42 A; 
#chains in the Genus database with same CATH topology
 4OZE A;  4X64 I;  3M7N D;  2WP8 B;  4OKG A;  5C0X D;  2IOQ A;  3PYF A;  2C37 A;  4DR7 I;  4LFA E;  2Z5E A;  2VQE I;  1FWK A;  1OYS A;  1IBM I;  4OO1 F;  2PO1 B;  2VQF I;  1Y6Z A;  4DU7 A;  3QT6 A;  4U3B A;  2PO0 A;  4FW5 A;  4DR3 E;  5FWK A;  2PNZ B;  2BA0 D;  1J5E I;  2A2C A;  3P3E A;  4PU9 A;  4DV4 I;  4LFC E;  5DNX A;  1Z0C A;  1N34 E;  4JI4 I;  2BR2 B;  4FWG A;  4X62 E;  2O1T A;  1N32 E;  3P06 A;  4LF9 E;  4LCG A;  4NXN I;  4DV2 I;  3T1H E;  4USM A;  3GME A;  2O1V A;  1VI7 A;  1FWL A;  2WNR B;  2UXB E;  2BV3 A;  1HNZ I;  4FWD A;  4U3D A;  3JAM Q;  1UDQ A;  4K0K I;  3HKM A;  4NBQ A;  4JI6 E;  2HFS A;  4B3M E;  4DV0 E;  5JEA B;  4FW7 A;  1UDN A;  1ZXN A;  2GO3 A;  3P3C A;  5IWA I;  2IOP A;  2Z5B B;  2PO2 B;  3PS1 A;  4LF8 E;  4HAC A;  5K36 B;  3J80 C;  2VES A;  3CDI A;  4R1F A;  3GCM A;  1N33 I;  1XMQ I;  4JI1 I;  3J81 Q;  2UXD E;  4B3S E;  4QNJ A;  4FWH A;  4ED4 A;  4JI2 E;  4PRV A;  4N3O A;  4FW4 A;  1ZM3 A;  2DEJ A;  1H72 C;  1H73 A;  4DV6 I;  2UXC E;  2O1W A;  3P76 A;  5K36 C;  4JV5 E;  4JI3 I;  3CDJ A;  4DV5 E;  2JEA A;  4OO1 D;  2AJ4 A;  3PS2 A;  1I94 I;  4DV7 I;  1BKN A;  4MU1 A;  4LFB E;  5K36 E;  4IFD A;  4JI5 E;  2CG9 A;  1HNW I;  3B82 A;  4BA2 A;  2PO0 B;  4JI8 I;  3M6A A;  4USK A;  4WUB A;  4DR5 E;  2BA1 D;  3ZKD A;  3ZZT A;  5BR8 I;  4RPF A;  3UHM A;  3PYD A;  5A2Q C;  1IBK E;  1Y60 A;  1Z59 A;  1RRE A;  3WU3 A;  5K36 F;  1N36 I;  3T1Y E;  3F0N A;  4IZJ D;  1Y4S A;  3M7N G;  3PYG A;  1XHK A;  2BM0 A;  4DR2 E;  4AQY E;  4B3R I;  2LJP A;  2HHH E;  2AE8 A;  2CZ9 A;  1HK7 A;  2JEB A;  1P42 A;  2UUC E;  4LFC I;  4XTJ A;  4DU8 A;  1Y5Y A;  4YHH E;  2V8P A;  4MU3 A;  4X62 I;  1N0V C;  1YHC A;  5ELW A;  1RR9 A;  4LF9 I;  3NZK A;  2UUB E;  2BA0 G;  4HAC B;  3GON A;  1Y4U A;  3PYE A;  4YY3 I;  2ZM6 E;  4IS9 A;  4LCF A;  2UXB I;  4DV1 E;  1HNX E;  4FW9 A;  2UUA E;  2WW4 A;  3CWV A;  4P7A A;  1D6T A;  3Q6M A;  4LF6 E;  4DUY I;  4DV0 I;  4BA1 A;  1NHJ A;  1EI1 A;  5IT9 Q;  4X65 E;  1Z0E A;  1MX0 A;  1FJG E;  1XMO E;  4LF8 I;  3D4J A;  2ZBK B;  2V2Z A;  3OTO I;  4GKJ E;  3GLL A;  4MDT A;  2JEA B;  3K1J A;  1S16 A;  4LF5 E;  4JI7 E;  4DPX A;  4LF7 E;  4OX9 I;  5LMN E;  4GKK I;  1EA6 A;  2UXD I;  3QT7 A;  4NXM E;  4FW3 A;  4B3S I;  2F4V E;  4JYA I;  2NN6 C;  4IFD B;  2E1R A;  4JI2 I;  1FNM A;  2GS8 A;  4BA2 B;  5FLX Q;  5JEA D;  3B4T A;  3ZM7 A;  2J7K A;  2UXC I;  3L7Z A;  1XNQ E;  1MG7 A;  3M85 D;  4Z7Y A;  4DV5 I;  5K36 D;  2CVE A;  3B8H A;  2HKJ A;  2NN6 E;  4KHP E;  3KRN A;  3LPS A;  4B3T I;  1MU5 A;  1IBM E;  4LFB I;  4IZJ A;  1XNR E;  5C0X E;  4LOM A;  2E5L E;  4IFD C;  1FI4 A;  4JI5 I;  4DV3 E;  4KQV A;  4DR1 I;  1OYR A;  2ZIT A;  4LF4 I;  4JI0 E;  2NN6 A;  2EFG A;  4URL A;  2C39 A;  5EKW A;  4MYU A;  4MU0 A;  4IZK A;  2OI2 A;  4IFD E;  3HJC A;  2JEB B;  4HXZ A;  3V5R A;  4JI4 E;  3DD6 A;  2JE6 A;  5C0X A;  1NHI A;  1USU A;  2A2D A;  2PNL A;  5DNL A;  4WUC A;  3ZZU A;  1Z0W A;  2HK2 A;  1HR0 E;  2R3V A;  4DUZ I;  2PNM A;  4AID A;  4X66 I;  3T1Y I;  2BA1 G;  1H74 A;  1DAR A;  4DPY A;  4AQY I;  3WU4 A;  3K17 A;  1KTV A;  5LMU E;  2UU9 E;  4IFD F;  2UUC I;  1K47 A;  1ZXM A;  2VF3 A;  3J7A M;  2Z5C A;  4YHH I;  2V2V A;  4BA1 B;  4DPW A;  3QT5 A;  1R6L A;  2UUB I;  4LFA I;  1N33 E;  4DR4 E;  1XMQ E;  3HUL A;  4DV1 I;  5GMD A;  1VIS A;  2X7I A;  5LL6 R;  1HNX I;  2UUA I;  1PIE A;  4DXL A;  4DR3 I;  4AIM A;  3JAM C;  4LF6 I;  2HKE A;  1ZM9 A;  5FLX C;  2X36 A;  3WU6 A;  1RHY A;  4X65 I;  5GME A;  2NPF A;  1N34 I;  5DRR A;  4OO1 C;  1FJG I;  1XXE A;  3L7Z B;  1N32 I;  4GKJ I;  3LNU A;  4DR6 E;  4LPF A;  4DV7 E;  1USV A;  4MQY A;  3T1H I;  4LF7 I;  1HNW E;  1IBL E;  4OO1 E;  4IZJ B;  4AM3 A;  3J81 C;  1PVG A;  2IES A;  1Z5A A;  1R6M A;  4JI6 I;  1U2R A;  5DRP A;  4B3M I;  1Z5C A;  1Z5B A;  4GQU A;  4ZVI A;  1QZR A;  2NN6 B;  1XNQ I;  1N0U A;  1Z0B A;  5BR8 E;  2C39 B;  2IER A;  1OYP A;  1OJ4 A;  4IZK B;  4EMD A;  4KHP I;  4OO1 A;  4Z7C A;  4FW6 A;  2JE6 B;  5C0X B;  1N36 E;  1WUU A;  1XNR I;  2E5L I;  1KIJ A;  3U1K A;  4J3D A;  4DV3 I;  5DRO A;  4IFD D;  4DPU A;  3M85 G;  4B3R E;  2C38 A;  2HFU A;  4JI0 I;  3Q6N A;  1S4E A;  1UEK A;  4X64 E;  1KKH A;  4ISA A;  5A2Q Q;  5C0X C;  3PS3 A;  4JV5 I;  2O1U A;  1Z0G A;  3U1Y A;  4P52 A;  2Z5C B;  1Z0V A;  4DPT A;  2O3Z A;  4DR7 E;  1H7U A;  3ZKB A;  1HR0 I;  3H4L A;  4HY1 A;  2VQE E;  2F1D A;  4YY3 E;  4UTG A;  3ZZ0 A;  2VQF E;  4JG4 A;  3K85 A;  4WUD A;  5LMU I;  2UU9 I;  4DUY E;  1J5E E;  4M1K A;  2WP8 A;  3WU5 A;  2V34 A;  4DV4 E;  4DR5 I;  1A6F A;  2V2Q A;  2NN6 F;  3LTO A;  2J65 A;  1E3P A;  1IBK I;  3OTO E;  2PO1 A;  4NXN E;  4DV2 E;  2GQ0 A;  5C0X F;  4DR4 I;  1NZ0 A;  1FKA E;  4PRX A;  1B62 A;  4OX9 E;  4GKK E;  1E3H A;  1ZM2 A;  2PNZ A;  1PKP A;  4I3H A;  1HNZ E;  4JYA E;  4DR2 I;  5JEA C;  4FN5 A;  4K0K E;  2HHH I;  2CGE A;  2DEI A;  2BR2 A;  1Z0T A;  5DRQ A;  5IT9 C;  4UT4 A;  5IWA E;  1YH8 A;  4DR6 I;  5JEA E;  4B3T E;  2R42 A;  2WNR A;  2C37 B;  4OO1 B;  2XEX A;  3J7A G;  1UDS A;  2ZM6 I;  1IBL I;  4JI1 E;  4DR1 E;  3B78 A;  1KVK A;  4LF4 E;  1ELO A;  2Q2E B;  5JEA A;  2C38 B;  2JT2 A;  4DV6 E;  2Z5B A;  2PO2 A;  5JEA F;  3P3G A;  4LCH A;  5K36 A;  4JI3 E;  1XMO I;  4MYT A;  3J80 Q;  1I94 E;  2BM1 A;  4MU4 A;  1ZM4 A;  4DUZ E;  3QT8 A;  3PRY A;  4X66 E;  4LF5 I;  1B63 A;  4JI7 I;  3H1C A;  3V2U C;  1UDO A;  5LMN I;  4NXM I;  3Q1Q A;  2F4V I;  4QNK A;  4HYM A;  5EL9 A;  2GO4 A;  1NHH A;  2HK3 A;  5L3J A;  2NN6 D;  4JI8 E;  1H7S A; 
#chains in the Genus database with same CATH homology
 2JT2 A;  4OZE A;  4ISA A;  5DRQ A;  4FW7 A;  3P3G A;  2IER A;  3P76 A;  4LCH A;  3UHM A;  3PS3 A;  3P3C A;  2GO3 A;  5DRR A;  3U1Y A;  2J65 A;  1XXE A;  1YHC A;  4OKG A;  1YH8 A;  3NZK A;  3PS1 A;  3PS2 A;  4LCG A;  2O3Z A;  4FW6 A;  4MDT A;  2VES A;  4MQY A;  4J3D A;  4IS9 A;  4LCF A;  4U3B A;  5DRO A;  4FW3 A;  4U3D A;  4FW5 A;  2IES A;  2GO4 A;  5DRP A;  4FW4 A;  3P3E A;  1P42 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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