1P42A

Crystal structure of aquifex aeolicus lpxc deacetylase (zinc-inhibited form)
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Crystal Structure of LpxC, a Zinc-Dependent Deacetylase Essential for Endotoxin Biosynthesis
pubmed doi rcsb
source organism Aquifex aeolicus
total genus 90
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2003-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1p42A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1p42A02
4FW6A 4FW3A 1XXEA 4LCFA 2O3ZA 4MDTA 3PS2A 5DRRA 3P3EA 4FW5A 4MQYA 3P3GA 2IESA 2JT2A 3P3CA 5DROA 5DRPA 3P76A 4OZEA 4FW4A 2VESA 2GO3A 1P42A 2J65A 1YH8A 4U3BA 3U1YA 2IERA 5DRQA 3NZKA 4OKGA 3PS1A 1YHCA 4ISAA 4FW7A 3UHMA 2GO4A 4J3DA 4LCHA 4IS9A 4LCGA 3PS3A 4U3DA
chains in the Genus database with same CATH superfamily
1H7SA 5K36F 4DV6I 3F0NA 1N32I 2ZBKB 1N36E 1XNRI 1S16A 4JI5I 3P3EA 4X65E 3P3CA 4FWDA 1Y4SA 2AJ4A 4HXZA 5DRPA 4B3TE 2BM1A 4OO1E 4LF5E 4DUYE 3GCMA 5K36C 2Z5BA 1U2RA 5ELWA 1H7UA 4JI2I 4USKA 3HKMA 4B3RE 5BR8E 4BA2B 2PO0B 2HKEA 4IZKA 3ZKDA 4JI4I 3ZZUA 4EMDA 4OO1B 1H73A 4FWGA 1PVGA 5LMNI 4WUCA 5LL6R 4YY3E 5IT9Q 1R6LA 1Z5BA 4NXMI 4IZJB 2JE6A 2O3ZA 4MDTA 3LPSA 3B78A 1NHJA 4LFCI 2Z5CA 3QT5A 2DEIA 4DV5E 2IOPA 3PYDA 3J81Q 4DR4E 1Y4UA 5C0XA 2UXCI 2HK3A 3CDJA 4DV1E 2J65A 2UXBI 4DR3E 4GQUA 2EFGA 2BA1D 4USMA 1I94I 2HHHE 2BR2A 4IS9A 2WNRA 2O1WA 1HNWI 4GKJE 2WW4A 5FWKA 4LCFA 4DPUA 5DRRA 5GMEA 1VI7A 1KKHA 1D6TA 3K85A 3J7AG 3K1JA 2CGEA 5C0XD 2NPFA 1HNXE 3D4JA 5IWAI 4X66I 1YHCA 2PNLA 4DU8A 4LFBI 4DPWA 3V5RA 4DUZE 4DR2E 4IFDF 3PYFA 4LCGA 3CDIA 2X36A 3WU3A 1USVA 4IZJA 4JI0E 3GMEA 4JI1E 2E5LI 3T1HI 3OTOI 4NXNE 4IFDC 4UT4A 4JI6E 4LF8I 5JEAE 4DV2E 1DARA 2Z5BB 4GKKE 2Q2EB 4I3HA 4FWHA 4N3OA 5DNLA 1N33E 2V8PA 4IZKB 1N36I 2J7KA 4QNKA 1OYRA 4FW3A 1XXEA 4X65I 4IZJD 5JEAB 4AM3A 1XMOE 4B3TI 3M85G 4MQYA 2JE6B 4LF5I 4DUYI 4MU1A 1ZXMA 2Z5CB 2CG9A 3L7ZB 1YH8A 4B3RI 5BR8I 1A6FA 4YY3I 1IBLE 5IT9C 4KHPE 1Y5YA 4X62E 2WNRB 3H4LA 4DV5I 5K36B 3QT6A 4DR4I 3J81C 2BA0D 1R6MA 4DV1I 2DEJA 3QT7A 4MU4A 4DR3I 1OYPA 1B62A 1N0VC 2OI2A 1ZM3A 4P52A 2UUCE 3J80Q 2HHHI 2VQFE 1MG7A 4LF9E 1ELOA 4K0KE 2HK2A 4GKJI 4DPYA 4DR1E 3H1CA 3T1YE 1UDOA 4DXLA 5JEAA 1ZM2A 1S4EA 2A2CA 2O1VA 1Z5CA 4FW5A 3HULA 1PIEA 2JT2A 5EL9A 2NN6F 3PYGA 1WUUA 3K17A 1USUA 2O1TA 3KRNA 3L7ZA 4JI3E 4DV7E 3B8HA 1HNXI 2HFSA 4Z7CA 1UDSA 3U1YA 4OO1F 2JEBB 4DUZI 4DR2I 4Z7YA 4JG4A 4FW7A 2NN6C 4JI0I 4J3DA 2C39B 2VQEE 3PS3A 2Z5EA 4JI1I 2LJPA 4FN5A 5LMUE 5K36A 5A2QQ 3PS2A 4OO1C 5JEAD 3B4TA 4NXNI 1N34E 1NZ0A 3ZZ0A 4JI6I 3GLLA 4DV2I 4JI7E 2HFUA 4IFDE 4GKKI 3CWVA 2R42A 1H72C 2JEAA 1Z0GA 4ISAA 4AQYE 1N33I 1HR0E 1IBME 4LCHA 3GONA 4MU0A 1EA6A 4FW6A 2UU9E 1XMOI 1FJGE 1EI1A 4IFDB 1XNQE 4RPFA 4WUBA 1N0UA 5K36D 2BA1G 4FW9A 5DROA 2VF3A 3P76A 4DR7E 1FI4A 2F4VE 2F1DA 2PO2A 2JEBA 3M85D 3Q1QA 1HK7A 1IBLI 4KHPI 2C39A 1PKPA 4X62I 3ZM7A 2IOQA 4U3DA 1NHHA 4AIMA 3M7NG 3ZZTA 4DPTA 1RHYA 2X7IA 1MX0A 4DV0E 4HACB 1Y60A 2V34A 2UUCI 1XMQE 2V2ZA 1Y6ZA 2CVEA 4OX9E 2ZM6E 1IBKE 3J80C 2VQFI 4DU7A 1B63A 4X64E 4LF9I 4K0KI 4OKGA 5K36E 1Z0BA 4DR1I 1KIJA 4PU9A 3T1YI 4PRVA 4LOMA 4DPXA 4IFDA 4QNJA 2PO1B 4JV5E 2WP8B 2BM0A 4M1KA 3ZKBA 2V2VA 4JYAE 3M6AA 4LFAE 4JI3I 4DV7I 5C0XF 1Z0VA 2C38B 4B3ME 2PNMA 2UXDE 3JAMQ 1BKNA 1Z0CA 2UUAE 4JI8E 2C37B 3V2UC 3PRYA 2GS8A 4LPFA 4MU3A 2VQEI 4LF6E 5C0XC 2JEAB 4YHHE 2ZITA 2A2DA 5LMUI 2UUBE 2HKJA 2NN6E 4DR5E 5A2QC 1N34I 1Z0EA 5FLXQ 4B3SE 4HACA 4IFDD 1E3HA 3DD6A 4LF4I 4JI7I 1J5EE 1UDQA 4FW4A 4AIDA 4LF7E 5EKWA 1MU5A 3J7AM 4URLA 4AQYI 2NN6B 3LTOA 3Q6NA 1OYSA 1HR0I 2PNZB 2PO2B 1IBMI 1Z0TA 4DR6E 2UU9I 4DV4E 5L3JA 2AE8A 1FJGI 2GQ0A 2BA0G 4PRXA 2PO1A 1XNQI 2WP8A 1VISA 4LF4E 1HNZE 4DV6E 1N32E 2C38A 2CZ9A 4DR7I 1UDNA 3HJCA 4DV3I 2F4VI 1XNRE 4BA1B 4JI5E 3QT8A 4OZEA 2C37A 1FNMA 2GO3A 1P42A 4KQVA 1RR9A 1FKAE 3NZKA 3UHMA 4JI2E 2E1RA 1XHKA 4JI4E 4DV0I 5LMNE 3WU6A 4ED4A 4NXME 1XMQI 2R3VA 2IESA 4OX9I 2ZM6I 1QZRA 1IBKI 4LFCE 3M7ND 4X64I 4MYUA 1UEKA 2NN6A 4DV3E 2PNZA 4U3BA 2IERA 4BA2A 2PO0A 2UXCE 1Z59A 4R1FA 2UXBE 4P7AA 4OO1A 5DNXA 2GO4A 1Z5AA 4HYMA 4JV5I 1I94E 4JYAI 4LFAI 1HNWE 1OJ4A 4B3MI 2UXDI 4BA1A 3LNUA 1FWKA 3WU4A 2UUAI 3JAMC 4JI8I 1NHIA 1ZM9A 3U1KA 2VESA 1ZXNA 2BV3A 1ZM4A 2NN6D 4LF6I 4YHHI 3PYEA 4HY1A 2UUBI 4NBQA 5IWAE 4X66E 2O1UA 4DR5I 4XTJA 5JEAF 4LFBE 4B3SI 4OO1D 5C0XE 4UTGA 5FLXC 1Z0WA 1KVKA 3Q6MA 1E3PA 5GMDA 1J5EI 1H74A 4MYTA 2XEXA 4LF7I 3P3GA 2V2QA 3B82A 1K47A 5JEAC 1KTVA 2E5LE 3T1HE 3OTOE 4ZVIA 4WUDA 5C0XB 5DRQA 4DR6I 3PS1A 4DV4I 4LF8E 1RREA 1FWLA 3P06A 3WU5A 2BR2B 1HNZI
chains in the Genus database with same CATH topology
4FW6A 4FW3A 1XXEA 4LCFA 2O3ZA 4MDTA 3PS2A 5DRRA 3P3EA 4FW5A 4MQYA 3P3GA 2IESA 2JT2A 3P3CA 5DROA 5DRPA 3P76A 4OZEA 4FW4A 2VESA 2GO3A 1P42A 2J65A 1YH8A 4U3BA 3U1YA 2IERA 5DRQA 3NZKA 4OKGA 3PS1A 1YHCA 4ISAA 4FW7A 3UHMA 2GO4A 4J3DA 4LCHA 4IS9A 4LCGA 3PS3A 4U3DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FW6 A;  4FW3 A;  1XXE A;  4LCF A;  2O3Z A;  4MDT A;  3PS2 A;  5DRR A;  3P3E A;  4FW5 A;  4MQY A;  3P3G A;  2IES A;  2JT2 A;  3P3C A;  5DRO A;  5DRP A;  3P76 A;  4OZE A;  4FW4 A;  2VES A;  2GO3 A;  1P42 A;  2J65 A;  1YH8 A;  4U3B A;  3U1Y A;  2IER A;  5DRQ A;  3NZK A;  4OKG A;  3PS1 A;  1YHC A;  4ISA A;  4FW7 A;  3UHM A;  2GO4 A;  4J3D A;  4LCH A;  4IS9 A;  4LCG A;  3PS3 A;  4U3D A; 
#chains in the Genus database with same CATH topology
 1H7S A;  5K36 F;  4DV6 I;  3F0N A;  1N32 I;  2ZBK B;  1N36 E;  1XNR I;  1S16 A;  4JI5 I;  3P3E A;  4X65 E;  3P3C A;  4FWD A;  1Y4S A;  2AJ4 A;  4HXZ A;  5DRP A;  4B3T E;  2BM1 A;  4OO1 E;  4LF5 E;  4DUY E;  3GCM A;  5K36 C;  2Z5B A;  1U2R A;  5ELW A;  1H7U A;  4JI2 I;  4USK A;  3HKM A;  4B3R E;  5BR8 E;  4BA2 B;  2PO0 B;  2HKE A;  4IZK A;  3ZKD A;  4JI4 I;  3ZZU A;  4EMD A;  4OO1 B;  1H73 A;  4FWG A;  1PVG A;  5LMN I;  4WUC A;  5LL6 R;  4YY3 E;  5IT9 Q;  1R6L A;  1Z5B A;  4NXM I;  4IZJ B;  2JE6 A;  2O3Z A;  4MDT A;  3LPS A;  3B78 A;  1NHJ A;  4LFC I;  2Z5C A;  3QT5 A;  2DEI A;  4DV5 E;  2IOP A;  3PYD A;  3J81 Q;  4DR4 E;  1Y4U A;  5C0X A;  2UXC I;  2HK3 A;  3CDJ A;  4DV1 E;  2J65 A;  2UXB I;  4DR3 E;  4GQU A;  2EFG A;  2BA1 D;  4USM A;  1I94 I;  2HHH E;  2BR2 A;  4IS9 A;  2WNR A;  2O1W A;  1HNW I;  4GKJ E;  2WW4 A;  5FWK A;  4LCF A;  4DPU A;  5DRR A;  5GME A;  1VI7 A;  1KKH A;  1D6T A;  3K85 A;  3J7A G;  3K1J A;  2CGE A;  5C0X D;  2NPF A;  1HNX E;  3D4J A;  5IWA I;  4X66 I;  1YHC A;  2PNL A;  4DU8 A;  4LFB I;  4DPW A;  3V5R A;  4DUZ E;  4DR2 E;  4IFD F;  3PYF A;  4LCG A;  3CDI A;  2X36 A;  3WU3 A;  1USV A;  4IZJ A;  4JI0 E;  3GME A;  4JI1 E;  2E5L I;  3T1H I;  3OTO I;  4NXN E;  4IFD C;  4UT4 A;  4JI6 E;  4LF8 I;  5JEA E;  4DV2 E;  1DAR A;  2Z5B B;  4GKK E;  2Q2E B;  4I3H A;  4FWH A;  4N3O A;  5DNL A;  1N33 E;  2V8P A;  4IZK B;  1N36 I;  2J7K A;  4QNK A;  1OYR A;  4FW3 A;  1XXE A;  4X65 I;  4IZJ D;  5JEA B;  4AM3 A;  1XMO E;  4B3T I;  3M85 G;  4MQY A;  2JE6 B;  4LF5 I;  4DUY I;  4MU1 A;  1ZXM A;  2Z5C B;  2CG9 A;  3L7Z B;  1YH8 A;  4B3R I;  5BR8 I;  1A6F A;  4YY3 I;  1IBL E;  5IT9 C;  4KHP E;  1Y5Y A;  4X62 E;  2WNR B;  3H4L A;  4DV5 I;  5K36 B;  3QT6 A;  4DR4 I;  3J81 C;  2BA0 D;  1R6M A;  4DV1 I;  2DEJ A;  3QT7 A;  4MU4 A;  4DR3 I;  1OYP A;  1B62 A;  1N0V C;  2OI2 A;  1ZM3 A;  4P52 A;  2UUC E;  3J80 Q;  2HHH I;  2VQF E;  1MG7 A;  4LF9 E;  1ELO A;  4K0K E;  2HK2 A;  4GKJ I;  4DPY A;  4DR1 E;  3H1C A;  3T1Y E;  1UDO A;  4DXL A;  5JEA A;  1ZM2 A;  1S4E A;  2A2C A;  2O1V A;  1Z5C A;  4FW5 A;  3HUL A;  1PIE A;  2JT2 A;  5EL9 A;  2NN6 F;  3PYG A;  1WUU A;  3K17 A;  1USU A;  2O1T A;  3KRN A;  3L7Z A;  4JI3 E;  4DV7 E;  3B8H A;  1HNX I;  2HFS A;  4Z7C A;  1UDS A;  3U1Y A;  4OO1 F;  2JEB B;  4DUZ I;  4DR2 I;  4Z7Y A;  4JG4 A;  4FW7 A;  2NN6 C;  4JI0 I;  4J3D A;  2C39 B;  2VQE E;  3PS3 A;  2Z5E A;  4JI1 I;  2LJP A;  4FN5 A;  5LMU E;  5K36 A;  5A2Q Q;  3PS2 A;  4OO1 C;  5JEA D;  3B4T A;  4NXN I;  1N34 E;  1NZ0 A;  3ZZ0 A;  4JI6 I;  3GLL A;  4DV2 I;  4JI7 E;  2HFU A;  4IFD E;  4GKK I;  3CWV A;  2R42 A;  1H72 C;  2JEA A;  1Z0G A;  4ISA A;  4AQY E;  1N33 I;  1HR0 E;  1IBM E;  4LCH A;  3GON A;  4MU0 A;  1EA6 A;  4FW6 A;  2UU9 E;  1XMO I;  1FJG E;  1EI1 A;  4IFD B;  1XNQ E;  4RPF A;  4WUB A;  1N0U A;  5K36 D;  2BA1 G;  4FW9 A;  5DRO A;  2VF3 A;  3P76 A;  4DR7 E;  1FI4 A;  2F4V E;  2F1D A;  2PO2 A;  2JEB A;  3M85 D;  3Q1Q A;  1HK7 A;  1IBL I;  4KHP I;  2C39 A;  1PKP A;  4X62 I;  3ZM7 A;  2IOQ A;  4U3D A;  1NHH A;  4AIM A;  3M7N G;  3ZZT A;  4DPT A;  1RHY A;  2X7I A;  1MX0 A;  4DV0 E;  4HAC B;  1Y60 A;  2V34 A;  2UUC I;  1XMQ E;  2V2Z A;  1Y6Z A;  2CVE A;  4OX9 E;  2ZM6 E;  1IBK E;  3J80 C;  2VQF I;  4DU7 A;  1B63 A;  4X64 E;  4LF9 I;  4K0K I;  4OKG A;  5K36 E;  1Z0B A;  4DR1 I;  1KIJ A;  4PU9 A;  3T1Y I;  4PRV A;  4LOM A;  4DPX A;  4IFD A;  4QNJ A;  2PO1 B;  4JV5 E;  2WP8 B;  2BM0 A;  4M1K A;  3ZKB A;  2V2V A;  4JYA E;  3M6A A;  4LFA E;  4JI3 I;  4DV7 I;  5C0X F;  1Z0V A;  2C38 B;  4B3M E;  2PNM A;  2UXD E;  3JAM Q;  1BKN A;  1Z0C A;  2UUA E;  4JI8 E;  2C37 B;  3V2U C;  3PRY A;  2GS8 A;  4LPF A;  4MU3 A;  2VQE I;  4LF6 E;  5C0X C;  2JEA B;  4YHH E;  2ZIT A;  2A2D A;  5LMU I;  2UUB E;  2HKJ A;  2NN6 E;  4DR5 E;  5A2Q C;  1N34 I;  1Z0E A;  5FLX Q;  4B3S E;  4HAC A;  4IFD D;  1E3H A;  3DD6 A;  4LF4 I;  4JI7 I;  1J5E E;  1UDQ A;  4FW4 A;  4AID A;  4LF7 E;  5EKW A;  1MU5 A;  3J7A M;  4URL A;  4AQY I;  2NN6 B;  3LTO A;  3Q6N A;  1OYS A;  1HR0 I;  2PNZ B;  2PO2 B;  1IBM I;  1Z0T A;  4DR6 E;  2UU9 I;  4DV4 E;  5L3J A;  2AE8 A;  1FJG I;  2GQ0 A;  2BA0 G;  4PRX A;  2PO1 A;  1XNQ I;  2WP8 A;  1VIS A;  4LF4 E;  1HNZ E;  4DV6 E;  1N32 E;  2C38 A;  2CZ9 A;  4DR7 I;  1UDN A;  3HJC A;  4DV3 I;  2F4V I;  1XNR E;  4BA1 B;  4JI5 E;  3QT8 A;  4OZE A;  2C37 A;  1FNM A;  2GO3 A;  1P42 A;  4KQV A;  1RR9 A;  1FKA E;  3NZK A;  3UHM A;  4JI2 E;  2E1R A;  1XHK A;  4JI4 E;  4DV0 I;  5LMN E;  3WU6 A;  4ED4 A;  4NXM E;  1XMQ I;  2R3V A;  2IES A;  4OX9 I;  2ZM6 I;  1QZR A;  1IBK I;  4LFC E;  3M7N D;  4X64 I;  4MYU A;  1UEK A;  2NN6 A;  4DV3 E;  2PNZ A;  4U3B A;  2IER A;  4BA2 A;  2PO0 A;  2UXC E;  1Z59 A;  4R1F A;  2UXB E;  4P7A A;  4OO1 A;  5DNX A;  2GO4 A;  1Z5A A;  4HYM A;  4JV5 I;  1I94 E;  4JYA I;  4LFA I;  1HNW E;  1OJ4 A;  4B3M I;  2UXD I;  4BA1 A;  3LNU A;  1FWK A;  3WU4 A;  2UUA I;  3JAM C;  4JI8 I;  1NHI A;  1ZM9 A;  3U1K A;  2VES A;  1ZXN A;  2BV3 A;  1ZM4 A;  2NN6 D;  4LF6 I;  4YHH I;  3PYE A;  4HY1 A;  2UUB I;  4NBQ A;  5IWA E;  4X66 E;  2O1U A;  4DR5 I;  4XTJ A;  5JEA F;  4LFB E;  4B3S I;  4OO1 D;  5C0X E;  4UTG A;  5FLX C;  1Z0W A;  1KVK A;  3Q6M A;  1E3P A;  5GMD A;  1J5E I;  1H74 A;  4MYT A;  2XEX A;  4LF7 I;  3P3G A;  2V2Q A;  3B82 A;  1K47 A;  5JEA C;  1KTV A;  2E5L E;  3T1H E;  3OTO E;  4ZVI A;  4WUD A;  5C0X B;  5DRQ A;  4DR6 I;  3PS1 A;  4DV4 I;  4LF8 E;  1RRE A;  1FWL A;  3P06 A;  3WU5 A;  2BR2 B;  1HNZ I; 
#chains in the Genus database with same CATH homology
 4FW6 A;  4FW3 A;  1XXE A;  4LCF A;  2O3Z A;  4MDT A;  3PS2 A;  5DRR A;  3P3E A;  4FW5 A;  4MQY A;  3P3G A;  2IES A;  2JT2 A;  3P3C A;  5DRO A;  5DRP A;  3P76 A;  4OZE A;  4FW4 A;  2VES A;  2GO3 A;  1P42 A;  2J65 A;  1YH8 A;  4U3B A;  3U1Y A;  2IER A;  5DRQ A;  3NZK A;  4OKG A;  3PS1 A;  1YHC A;  4ISA A;  4FW7 A;  3UHM A;  2GO4 A;  4J3D A;  4LCH A;  4IS9 A;  4LCG A;  3PS3 A;  4U3D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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