1P42A

Crystal structure of aquifex aeolicus lpxc deacetylase (zinc-inhibited form)
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of LpxC, a Zinc-Dependent Deacetylase Essential for Endotoxin Biosynthesis
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 90
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2003-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1p42A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1p42A02
4FW4A 5DRPA 1YH8A 3P3CA 4LCFA 3PS3A 4IS9A 4MQYA 5DROA 4OKGA 1P42A 3PS1A 4FW7A 2O3ZA 3P3GA 3PS2A 4FW5A 3U1YA 1YHCA 5DRRA 3NZKA 4ISAA 4LCHA 5DRQA 2IERA 2GO4A 4U3DA 2JT2A 3UHMA 2J65A 1XXEA 4FW3A 4J3DA 2IESA 4FW6A 2GO3A 4U3BA 3P76A 4LCGA 3P3EA 4OZEA 4MDTA 2VESA
chains in the Genus database with same CATH superfamily
3K1JA 1N33E 1Z0GA 2PO2A 4JI1E 1K47A 2BM0A 5K36E 2O3ZA 2VF3A 4PRVA 4MYUA 1IBMI 1ZXNA 3HKMA 2C38B 4UT4A 2BV3A 4DR4I 2WP8A 5GMEA 2UU9I 1XMOE 1J5EE 4KHPI 4JV5E 2WW4A 4GKJI 1MU5A 2UUAI 4DXLA 2O1TA 4NBQA 4IFDA 4RPFA 1OYSA 5K36F 4QNKA 4X62I 4B3TI 1KVKA 4WUDA 5FLXC 5JEAE 2F1DA 4DR1E 2C39A 1B62A 1S16A 2NN6A 2ZITA 3PS2A 2HK3A 5LMNE 1XHKA 3H4LA 4IZJA 3U1YA 4DV7I 1YHCA 4LF9E 3M7NG 4DU7A 2X7IA 5IT9Q 3OTOI 2PO1B 3L7ZB 1N32E 1HNWI 4LFBE 2VQFI 4Z7YA 2BA1D 4JI7E 4BA2B 1N32I 4LFAI 4IS9A 4FWGA 2JEBA 2V2QA 4JI2E 4FW7A 2HFSA 3J7AM 2PNZA 4GQUA 4DV2E 1Z5AA 1FJGE 4DUYE 4HACB 5LMUI 1OYPA 4MU3A 2GS8A 1H74A 4DR1I 1ZM3A 4USMA 2UXCI 1HNXE 1FWKA 1DARA 4DV4I 3PYFA 3ZZ0A 4LCFA 3QT8A 3M85D 2UUAE 2BA0D 4JI4I 2JEAB 1S4EA 4YHHE 4OO1E 3P3GA 4Z7CA 4LFCI 2WP8B 1Z0BA 5C0XD 3PYEA 4JI8I 3J80Q 3T1YI 3ZZTA 3B4TA 1KTVA 1XNRI 4DR7I 4FW9A 3OTOE 5FWKA 3PYGA 2O1VA 1PVGA 2UXBE 4OZEA 4PU9A 3GONA 2JE6B 3LNUA 1FKAE 5DRPA 5BR8I 3H1CA 3KRNA 2VQFE 4N3OA 2BA0G 4MU4A 4AQYI 1Y6ZA 1N36I 4EMDA 2X36A 5LMNI 4DPWA 4YY3E 4JI0I 2DEIA 1HR0E 5C0XE 2IESA 4OX9E 4YY3I 4FW6A 2GO3A 4DV6I 5JEAD 3DD6A 1FJGI 2HHHE 4DR4E 4LFAE 4MQYA 5LMUE 4B3RI 1RHYA 3Q1QA 3L7ZA 4LF7E 3JAMQ 1MG7A 4I3HA 1Z59A 4NXME 2C38A 5DRQA 2UUCE 1Y4SA 2JT2A 2NN6D 4FWDA 3UHMA 4DUZE 1ZM4A 1N33I 1Y5YA 4GKKE 2NN6F 2PNMA 3GCMA 3P3CA 1BKNA 1ZM2A 1Y60A 4HYMA 1ELOA 4FWHA 3GLLA 4OKGA 1P42A 1I94E 2LJPA 4ED4A 4WUCA 4P7AA 5K36D 4DR3I 4FW5A 2Z5CA 2IOQA 5DRRA 4JV5I 4JI5E 1UEKA 4IFDE 3WU6A 1IBLE 1XMOI 4AM3A 3T1HI 2C37B 5JEAA 3K85A 4DR5E 1Z0VA 1KIJA 4JI3E 1H7UA 3PRYA 3P3EA 2NN6E 2HHHI 4DV0I 4OO1C 2NN6C 4UTGA 4NXNE 1RREA 4B3ME 3LPSA 2EFGA 4IFDC 4MU0A 1U2RA 1Z0CA 1N34I 3CDIA 4LF5E 2AE8A 4IZKA 5DNLA 4IFDF 4GKKI 4IZKB 4BA1B 2UUBI 4DV5E 1XXEA 2Z5CB 4J3DA 3J81C 2E1RA 3QT7A 4U3BA 4LF4I 3K17A 1RR9A 1HK7A 2F4VE 4WUBA 4LPFA 4DUZI 3JAMC 1NHIA 4XTJA 4LF6I 4MU1A 4DR7E 1NHHA 2ZBKB 4LF5I 3U1KA 1XNQI 4DR5I 4JI3I 2GQ0A 2PO0B 4IZJB 2A2CA 4HXZA 4OX9I 4JG4A 3P76A 2CGEA 4LCGA 4X64I 1NZ0A 4MDTA 3V2UC 3M6AA 3D4JA 3ZM7A 5JEAC 2BA1G 5EL9A 4LF6E 1N0VC 2CZ9A 2JE6A 1I94I 4AIDA 5C0XC 5EKWA 1HNZI 3CWVA 2PO1A 4JYAE 4DR2E 4LF4E 2UXDI 2IERA 2UXBI 4K0KE 2J7KA 1Z5BA 5IWAE 3LTOA 2A2DA 2J65A 5A2QQ 4X65E 2UUCI 3T1YE 2ZM6E 3HJCA 4FW4A 2PO2B 5C0XB 1OYRA 4LFCE 4NXNI 4LF7I 5JEAF 4YHHI 2O1UA 3P06A 4ZVIA 2IOPA 3HULA 2C37A 2Z5EA 4DV3I 4OO1F 4USKA 2E5LI 4DV4E 2R3VA 2WNRA 3M7ND 2BM1A 4U3DA 1HR0I 4DR6I 5K36A 4P52A 4X66I 1XMQI 4FW3A 4JI4E 4B3TE 2BR2A 5DNXA 3WU4A 1HNXI 2JEBB 1VI7A 2XEXA 1E3HA 4X64E 2NPFA 1WUUA 1NHJA 3J80C 3PS1A 5ELWA 4DPTA 4X66E 4B3SE 5FLXQ 2HKJA 4OO1B 2CVEA 4DV3E 2HK2A 2Q2EB 4DV2I 2CG9A 4BA1A 2E5LE 4DUYI 2OI2A 1N36E 2DEJA 2WNRB 1A6FA 4JI7I 5C0XF 4MYTA 5IWAI 4NXMI 4FN5A 4JI1I 3WU5A 4LFBI 1H72C 3B78A 1QZRA 2F4VI 4JI8E 2Z5BB 4DV7E 4B3RE 4HY1A 4DR2I 4BA2A 4R1FA 3M85G 4IFDB 1XNRE 2Z5BA 1EI1A 3PS3A 4QNJA 3ZZUA 4B3SI 2BR2B 4K0KI 1OJ4A 1D6TA 2V2ZA 4DV6E 1FWLA 1UDNA 4LF9I 2UXCE 1Y4UA 2V2VA 1EA6A 4DV1I 4AIMA 4LCHA 3WU3A 2GO4A 1HNZE 4JI0E 4IFDD 3ZKDA 4DV1E 3GMEA 4DR6E 4KQVA 2JEAA 1R6MA 2VESA 3Q6NA 1Z0WA 1ZXMA 1YH8A 1FI4A 1ZM9A 1Z0EA 1Z5CA 1VISA 5A2QC 4IZJD 3QT6A 1IBKE 5BR8E 1B63A 1UDSA 2R42A 4JI2I 1UDQA 1XNQE 1IBME 4M1KA 4ISAA 2PO0A 4X65I 4DPXA 3CDJA 2VQEE 3V5RA 5K36C 4OO1A 2NN6B 2C39B 2ZM6I 4JYAI 1Z0TA 2UXDE 4DV5I 1FNMA 4X62E 5DROA 1R6LA 4DPYA 2VQEI 4JI6I 5JEAB 1N34E 3F0NA 4LOMA 5K36B 2HKEA 4DU8A 4B3MI 3J7AG 5LL6R 1XMQE 4HACA 1IBKI 1J5EI 4KHPE 4LF8I 5L3JA 2PNZB 3Q6MA 5IT9C 5GMDA 1N0UA 1UDOA 4GKJE 4DV0E 4LF8E 2HFUA 1USUA 2V34A 2UU9E 5C0XA 1IBLI 1USVA 4JI6E 2V8PA 2O1WA 3T1HE 1H73A 4JI5I 3ZKBA 2PNLA 3QT5A 3J81Q 1HNWE 1MX0A 1PKPA 1H7SA 3NZKA 4PRXA 4DR3E 4OO1D 1E3PA 4URLA 1KKHA 2AJ4A 4AQYE 2UUBE 3B8HA 4DPUA 3B82A 3PYDA 1PIEA
chains in the Genus database with same CATH topology
4FW4A 5DRPA 1YH8A 3P3CA 4LCFA 3PS3A 4IS9A 4MQYA 5DROA 4OKGA 1P42A 3PS1A 4FW7A 2O3ZA 3P3GA 3PS2A 4FW5A 3U1YA 1YHCA 5DRRA 3NZKA 4ISAA 4LCHA 5DRQA 2IERA 2GO4A 4U3DA 2JT2A 3UHMA 2J65A 1XXEA 4FW3A 4J3DA 2IESA 4FW6A 2GO3A 4U3BA 3P76A 4LCGA 3P3EA 4OZEA 4MDTA 2VESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FW4 A;  5DRP A;  1YH8 A;  3P3C A;  4LCF A;  3PS3 A;  4IS9 A;  4MQY A;  5DRO A;  4OKG A;  1P42 A;  3PS1 A;  4FW7 A;  2O3Z A;  3P3G A;  3PS2 A;  4FW5 A;  3U1Y A;  1YHC A;  5DRR A;  3NZK A;  4ISA A;  4LCH A;  5DRQ A;  2IER A;  2GO4 A;  4U3D A;  2JT2 A;  3UHM A;  2J65 A;  1XXE A;  4FW3 A;  4J3D A;  2IES A;  4FW6 A;  2GO3 A;  4U3B A;  3P76 A;  4LCG A;  3P3E A;  4OZE A;  4MDT A;  2VES A; 
#chains in the Genus database with same CATH topology
 3K1J A;  1N33 E;  1Z0G A;  2PO2 A;  4JI1 E;  1K47 A;  2BM0 A;  5K36 E;  2O3Z A;  2VF3 A;  4PRV A;  4MYU A;  1IBM I;  1ZXN A;  3HKM A;  2C38 B;  4UT4 A;  2BV3 A;  4DR4 I;  2WP8 A;  5GME A;  2UU9 I;  1XMO E;  1J5E E;  4KHP I;  4JV5 E;  2WW4 A;  4GKJ I;  1MU5 A;  2UUA I;  4DXL A;  2O1T A;  4NBQ A;  4IFD A;  4RPF A;  1OYS A;  5K36 F;  4QNK A;  4X62 I;  4B3T I;  1KVK A;  4WUD A;  5FLX C;  5JEA E;  2F1D A;  4DR1 E;  2C39 A;  1B62 A;  1S16 A;  2NN6 A;  2ZIT A;  3PS2 A;  2HK3 A;  5LMN E;  1XHK A;  3H4L A;  4IZJ A;  3U1Y A;  4DV7 I;  1YHC A;  4LF9 E;  3M7N G;  4DU7 A;  2X7I A;  5IT9 Q;  3OTO I;  2PO1 B;  3L7Z B;  1N32 E;  1HNW I;  4LFB E;  2VQF I;  4Z7Y A;  2BA1 D;  4JI7 E;  4BA2 B;  1N32 I;  4LFA I;  4IS9 A;  4FWG A;  2JEB A;  2V2Q A;  4JI2 E;  4FW7 A;  2HFS A;  3J7A M;  2PNZ A;  4GQU A;  4DV2 E;  1Z5A A;  1FJG E;  4DUY E;  4HAC B;  5LMU I;  1OYP A;  4MU3 A;  2GS8 A;  1H74 A;  4DR1 I;  1ZM3 A;  4USM A;  2UXC I;  1HNX E;  1FWK A;  1DAR A;  4DV4 I;  3PYF A;  3ZZ0 A;  4LCF A;  3QT8 A;  3M85 D;  2UUA E;  2BA0 D;  4JI4 I;  2JEA B;  1S4E A;  4YHH E;  4OO1 E;  3P3G A;  4Z7C A;  4LFC I;  2WP8 B;  1Z0B A;  5C0X D;  3PYE A;  4JI8 I;  3J80 Q;  3T1Y I;  3ZZT A;  3B4T A;  1KTV A;  1XNR I;  4DR7 I;  4FW9 A;  3OTO E;  5FWK A;  3PYG A;  2O1V A;  1PVG A;  2UXB E;  4OZE A;  4PU9 A;  3GON A;  2JE6 B;  3LNU A;  1FKA E;  5DRP A;  5BR8 I;  3H1C A;  3KRN A;  2VQF E;  4N3O A;  2BA0 G;  4MU4 A;  4AQY I;  1Y6Z A;  1N36 I;  4EMD A;  2X36 A;  5LMN I;  4DPW A;  4YY3 E;  4JI0 I;  2DEI A;  1HR0 E;  5C0X E;  2IES A;  4OX9 E;  4YY3 I;  4FW6 A;  2GO3 A;  4DV6 I;  5JEA D;  3DD6 A;  1FJG I;  2HHH E;  4DR4 E;  4LFA E;  4MQY A;  5LMU E;  4B3R I;  1RHY A;  3Q1Q A;  3L7Z A;  4LF7 E;  3JAM Q;  1MG7 A;  4I3H A;  1Z59 A;  4NXM E;  2C38 A;  5DRQ A;  2UUC E;  1Y4S A;  2JT2 A;  2NN6 D;  4FWD A;  3UHM A;  4DUZ E;  1ZM4 A;  1N33 I;  1Y5Y A;  4GKK E;  2NN6 F;  2PNM A;  3GCM A;  3P3C A;  1BKN A;  1ZM2 A;  1Y60 A;  4HYM A;  1ELO A;  4FWH A;  3GLL A;  4OKG A;  1P42 A;  1I94 E;  2LJP A;  4ED4 A;  4WUC A;  4P7A A;  5K36 D;  4DR3 I;  4FW5 A;  2Z5C A;  2IOQ A;  5DRR A;  4JV5 I;  4JI5 E;  1UEK A;  4IFD E;  3WU6 A;  1IBL E;  1XMO I;  4AM3 A;  3T1H I;  2C37 B;  5JEA A;  3K85 A;  4DR5 E;  1Z0V A;  1KIJ A;  4JI3 E;  1H7U A;  3PRY A;  3P3E A;  2NN6 E;  2HHH I;  4DV0 I;  4OO1 C;  2NN6 C;  4UTG A;  4NXN E;  1RRE A;  4B3M E;  3LPS A;  2EFG A;  4IFD C;  4MU0 A;  1U2R A;  1Z0C A;  1N34 I;  3CDI A;  4LF5 E;  2AE8 A;  4IZK A;  5DNL A;  4IFD F;  4GKK I;  4IZK B;  4BA1 B;  2UUB I;  4DV5 E;  1XXE A;  2Z5C B;  4J3D A;  3J81 C;  2E1R A;  3QT7 A;  4U3B A;  4LF4 I;  3K17 A;  1RR9 A;  1HK7 A;  2F4V E;  4WUB A;  4LPF A;  4DUZ I;  3JAM C;  1NHI A;  4XTJ A;  4LF6 I;  4MU1 A;  4DR7 E;  1NHH A;  2ZBK B;  4LF5 I;  3U1K A;  1XNQ I;  4DR5 I;  4JI3 I;  2GQ0 A;  2PO0 B;  4IZJ B;  2A2C A;  4HXZ A;  4OX9 I;  4JG4 A;  3P76 A;  2CGE A;  4LCG A;  4X64 I;  1NZ0 A;  4MDT A;  3V2U C;  3M6A A;  3D4J A;  3ZM7 A;  5JEA C;  2BA1 G;  5EL9 A;  4LF6 E;  1N0V C;  2CZ9 A;  2JE6 A;  1I94 I;  4AID A;  5C0X C;  5EKW A;  1HNZ I;  3CWV A;  2PO1 A;  4JYA E;  4DR2 E;  4LF4 E;  2UXD I;  2IER A;  2UXB I;  4K0K E;  2J7K A;  1Z5B A;  5IWA E;  3LTO A;  2A2D A;  2J65 A;  5A2Q Q;  4X65 E;  2UUC I;  3T1Y E;  2ZM6 E;  3HJC A;  4FW4 A;  2PO2 B;  5C0X B;  1OYR A;  4LFC E;  4NXN I;  4LF7 I;  5JEA F;  4YHH I;  2O1U A;  3P06 A;  4ZVI A;  2IOP A;  3HUL A;  2C37 A;  2Z5E A;  4DV3 I;  4OO1 F;  4USK A;  2E5L I;  4DV4 E;  2R3V A;  2WNR A;  3M7N D;  2BM1 A;  4U3D A;  1HR0 I;  4DR6 I;  5K36 A;  4P52 A;  4X66 I;  1XMQ I;  4FW3 A;  4JI4 E;  4B3T E;  2BR2 A;  5DNX A;  3WU4 A;  1HNX I;  2JEB B;  1VI7 A;  2XEX A;  1E3H A;  4X64 E;  2NPF A;  1WUU A;  1NHJ A;  3J80 C;  3PS1 A;  5ELW A;  4DPT A;  4X66 E;  4B3S E;  5FLX Q;  2HKJ A;  4OO1 B;  2CVE A;  4DV3 E;  2HK2 A;  2Q2E B;  4DV2 I;  2CG9 A;  4BA1 A;  2E5L E;  4DUY I;  2OI2 A;  1N36 E;  2DEJ A;  2WNR B;  1A6F A;  4JI7 I;  5C0X F;  4MYT A;  5IWA I;  4NXM I;  4FN5 A;  4JI1 I;  3WU5 A;  4LFB I;  1H72 C;  3B78 A;  1QZR A;  2F4V I;  4JI8 E;  2Z5B B;  4DV7 E;  4B3R E;  4HY1 A;  4DR2 I;  4BA2 A;  4R1F A;  3M85 G;  4IFD B;  1XNR E;  2Z5B A;  1EI1 A;  3PS3 A;  4QNJ A;  3ZZU A;  4B3S I;  2BR2 B;  4K0K I;  1OJ4 A;  1D6T A;  2V2Z A;  4DV6 E;  1FWL A;  1UDN A;  4LF9 I;  2UXC E;  1Y4U A;  2V2V A;  1EA6 A;  4DV1 I;  4AIM A;  4LCH A;  3WU3 A;  2GO4 A;  1HNZ E;  4JI0 E;  4IFD D;  3ZKD A;  4DV1 E;  3GME A;  4DR6 E;  4KQV A;  2JEA A;  1R6M A;  2VES A;  3Q6N A;  1Z0W A;  1ZXM A;  1YH8 A;  1FI4 A;  1ZM9 A;  1Z0E A;  1Z5C A;  1VIS A;  5A2Q C;  4IZJ D;  3QT6 A;  1IBK E;  5BR8 E;  1B63 A;  1UDS A;  2R42 A;  4JI2 I;  1UDQ A;  1XNQ E;  1IBM E;  4M1K A;  4ISA A;  2PO0 A;  4X65 I;  4DPX A;  3CDJ A;  2VQE E;  3V5R A;  5K36 C;  4OO1 A;  2NN6 B;  2C39 B;  2ZM6 I;  4JYA I;  1Z0T A;  2UXD E;  4DV5 I;  1FNM A;  4X62 E;  5DRO A;  1R6L A;  4DPY A;  2VQE I;  4JI6 I;  5JEA B;  1N34 E;  3F0N A;  4LOM A;  5K36 B;  2HKE A;  4DU8 A;  4B3M I;  3J7A G;  5LL6 R;  1XMQ E;  4HAC A;  1IBK I;  1J5E I;  4KHP E;  4LF8 I;  5L3J A;  2PNZ B;  3Q6M A;  5IT9 C;  5GMD A;  1N0U A;  1UDO A;  4GKJ E;  4DV0 E;  4LF8 E;  2HFU A;  1USU A;  2V34 A;  2UU9 E;  5C0X A;  1IBL I;  1USV A;  4JI6 E;  2V8P A;  2O1W A;  3T1H E;  1H73 A;  4JI5 I;  3ZKB A;  2PNL A;  3QT5 A;  3J81 Q;  1HNW E;  1MX0 A;  1PKP A;  1H7S A;  3NZK A;  4PRX A;  4DR3 E;  4OO1 D;  1E3P A;  4URL A;  1KKH A;  2AJ4 A;  4AQY E;  2UUB E;  3B8H A;  4DPU A;  3B82 A;  3PYD A;  1PIE A; 
#chains in the Genus database with same CATH homology
 4FW4 A;  5DRP A;  1YH8 A;  3P3C A;  4LCF A;  3PS3 A;  4IS9 A;  4MQY A;  5DRO A;  4OKG A;  1P42 A;  3PS1 A;  4FW7 A;  2O3Z A;  3P3G A;  3PS2 A;  4FW5 A;  3U1Y A;  1YHC A;  5DRR A;  3NZK A;  4ISA A;  4LCH A;  5DRQ A;  2IER A;  2GO4 A;  4U3D A;  2JT2 A;  3UHM A;  2J65 A;  1XXE A;  4FW3 A;  4J3D A;  2IES A;  4FW6 A;  2GO3 A;  4U3B A;  3P76 A;  4LCG A;  3P3E A;  4OZE A;  4MDT A;  2VES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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