1P42A

Crystal structure of aquifex aeolicus lpxc deacetylase (zinc-inhibited form)
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of LpxC, a Zinc-Dependent Deacetylase Essential for Endotoxin Biosynthesis
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 90
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2003-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1p42A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1p42A02
4LCGA 4FW4A 2VESA 4ISAA 3P3GA 4OKGA 4U3BA 4FW6A 3PS1A 4OZEA 4FW7A 3U1YA 1YHCA 3UHMA 1P42A 1YH8A 1XXEA 2IERA 2GO3A 4U3DA 4LCHA 4LCFA 5DRQA 5DROA 2J65A 2JT2A 4MDTA 4MQYA 2O3ZA 2IESA 4J3DA 2GO4A 4IS9A 5DRRA 3P76A 4FW3A 4FW5A 3P3CA 3NZKA 3PS2A 5DRPA 3P3EA 3PS3A
chains in the Genus database with same CATH superfamily
2UUCE 1FJGE 1S16A 1OYRA 4U3BA 4NXME 4JI3I 4HACA 3J80C 1YHCA 4R1FA 4LF9E 4YHHI 4FWGA 5LMUI 2JE6B 3V5RA 4DR1I 4B3ME 4MU3A 4U3DA 4DR6E 4BA1B 1I94I 1FNMA 2VQEE 4JI5I 2CZ9A 1N34E 3B8HA 3QT6A 4MU4A 2R42A 4GQUA 4MYTA 1HR0I 4DUYE 2C38A 1ELOA 5DRPA 1VI7A 3ZKDA 4DU8A 4DUYI 3V2UC 4DXLA 3M85G 2NN6B 2E1RA 4DR7E 5K36E 2NPFA 4FW6A 3D4JA 4OZEA 3PYEA 5FWKA 2GO3A 4LF4I 3ZZTA 2NN6F 4PU9A 4DPWA 2LJPA 3F0NA 4AIDA 4ZVIA 2UXCE 4DR2E 2WNRB 3OTOI 1XHKA 3P76A 4FN5A 5BR8E 4IZKB 5JEAD 3PS3A 4LCGA 4FW4A 4AM3A 3M7ND 1UDOA 4ISAA 2O1TA 1ZM2A 1Z0WA 3P3GA 1Z5AA 4IFDE 4KHPI 4WUCA 2JEAA 4OO1D 2NN6D 4MYUA 4N3OA 2JEBA 4BA2A 1VISA 1KVKA 1WUUA 4I3HA 3U1KA 4JI2E 4YY3I 2UXCI 4OO1B 3CDIA 2UUBE 3OTOE 3ZZUA 5BR8I 1OYSA 2IESA 5EL9A 4JI0I 1E3PA 1FWKA 1FI4A 5IT9Q 4DV6E 2HHHE 1KTVA 4DPUA 2A2CA 4JV5I 1XMQE 4JI4E 1Z0VA 1HK7A 5C0XB 1USUA 1Y4SA 4QNJA 2BM0A 2Z5CB 1IBKI 2UU9I 2UUAE 1PKPA 1NZ0A 3QT8A 1Z0EA 2UXDI 2WW4A 4JI1E 4B3RI 4OO1E 2PO2A 2J7KA 4IFDD 3T1HE 2HK3A 5FLXC 4IFDF 4DV6I 1N36I 3HKMA 5JEAE 1N33E 3GCMA 4DR4I 4B3SI 2EFGA 2C37A 3U1YA 4JI3E 4B3TI 2J65A 2GQ0A 4FWHA 5FLXQ 1NHJA 4LF7E 4NXNE 5LL6R 4DPTA 1MX0A 5K36B 4B3SE 2F4VE 4YHHE 4EMDA 2PO1B 2HFUA 1I94E 4USMA 1NHIA 3GMEA 4DV1E 2BA1D 2PNLA 5DRQA 1DARA 4MQYA 4DUZI 4DV3E 4DPYA 1S4EA 4MU1A 4JI7E 2NN6C 2UUBI 2PNZA 2CGEA 4X65I 1KIJA 2Z5CA 2HFSA 5C0XA 4PRXA 2JEAB 3LTOA 1H7SA 2VESA 3WU6A 1XNQI 4WUBA 1H74A 3CWVA 2BR2B 3LNUA 1ZXMA 4DV1I 2ZBKB 4LF8I 1XNRE 4Z7YA 4LFAE 3WU4A 2JT2A 1QZRA 4YY3E 4DV4I 2C37B 3J81Q 4GKKI 4HXZA 2BA0D 1KKHA 2O1WA 2PNMA 5LMNI 2E5LI 2BM1A 1HNWE 3CDJA 2C39A 3WU3A 4OO1C 4WUDA 1XMQI 1P42A 5C0XF 4K0KE 1IBKE 4FWDA 4DR5I 3K1JA 4JI8I 4JI0E 1Y5YA 2Q2EB 2R3VA 4OX9I 1D6TA 1NHHA 1RR9A 3K85A 4X64E 4HACB 4OX9E 3PS2A 1FJGI 2V8PA 5C0XE 2UXBE 1B63A 2UUCI 5GMEA 2VQFI 5DNXA 4FW7A 2HK2A 4DU7A 5IT9C 1IBLE 4GKJE 2C38B 2HKEA 1B62A 1ZM4A 4RPFA 4UTGA 4GKJI 2V2QA 1FWLA 4JI1I 4B3TE 1XMOI 4JI6E 2PO2B 5DNLA 4URLA 4DV3I 3T1YI 2GS8A 4IS9A 4AIMA 4FW3A 4DR2I 1R6MA 1Z0BA 4JYAI 2UXBI 3H4LA 3P3EA 1OYPA 3JAMQ 1E3HA 2F4VI 2AJ4A 1UEKA 4NXMI 4X62E 3PYFA 1N32E 1XNQE 1U2RA 3B82A 4X66I 4IZKA 1UDQA 1XMOE 2VF3A 4M1KA 2PO0B 1PIEA 4MDTA 1HNZE 1Y60A 1H72C 2F1DA 5GMDA 1HR0E 2X36A 5K36C 2BR2A 5DRRA 5EKWA 1J5EE 4IFDB 2V2VA 4MU0A 4XTJA 3QT7A 4X65E 1MG7A 2X7IA 4OKGA 2HHHI 4JV5E 2ZITA 4NBQA 3UHMA 1XNRI 3LPSA 4PRVA 4LF4E 3QT5A 1FKAE 4LCHA 4USKA 4LF8E 4LCFA 2OI2A 1H7UA 5JEAC 4DR5E 2DEIA 4DV2E 4IZJD 2UXDE 4B3RE 4J3DA 1K47A 1MU5A 1Z0TA 2O1UA 2DEJA 4P52A 5LMNE 4HYMA 4DV5I 2WP8B 4LF6I 4HY1A 3ZZ0A 4KHPE 4DV5E 1ZXNA 4OO1F 4JI4I 2NN6A 5K36A 1RREA 3ZM7A 1Z5CA 4ED4A 1IBMI 5JEAF 2IERA 3DD6A 4LOMA 1IBME 2WNRA 4KQVA 3K17A 5DROA 1RHYA 5A2QQ 3T1HI 2O3ZA 3P06A 2CG9A 4AQYI 4JI8E 4BA1A 1N36E 4LF5E 2AE8A 3Q1QA 1HNXE 3T1YE 1A6FA 3M85D 4LF7I 1HNXI 3GLLA 5L3JA 4IFDA 1IBLI 3HJCA 1EI1A 3PRYA 2UU9E 4UT4A 4DV0E 2WP8A 2VQFE 4DR6I 1Z5BA 4FW9A 4JG4A 2Z5EA 4DPXA 5C0XD 2VQEI 1UDNA 4DV7E 4LF9I 1N0VC 1N34I 5LMUE 4DR1E 4B3MI 3PYDA 4LFBI 2ZM6I 4LF5I 2CVEA 4X64I 1ZM3A 1R6LA 4LFBE 3WU5A 4QNKA 1PVGA 2ZM6E 2O1VA 1N33I 3J7AM 3JAMC 3NZKA 2BV3A 2GO4A 1J5EI 4JYAE 4NXNI 2NN6E 2A2DA 4DR7I 3PS1A 2PNZB 3Q6MA 3L7ZB 4LFCI 1UDSA 1XXEA 4LFCE 4X66E 4JI5E 3ZKBA 5K36F 1EA6A 4JI7I 4OO1A 3J80Q 1OJ4A 4DUZE 2JE6A 3J81C 5ELWA 4DV4E 2PO1A 4X62I 5JEAA 1USVA 1N32I 2IOQA 3B4TA 1ZM9A 1Z0CA 5A2QC 2HKJA 3GONA 4Z7CA 1YH8A 3Q6NA 1Z59A 4LPFA 2Z5BB 2UUAI 1HNZI 1H73A 4DR3I 4IZJB 4IFDC 3PYGA 4K0KI 5C0XC 4DR3E 2V2ZA 1N0UA 3HULA 2BA1G 4DV2I 3J7AG 2BA0G 2C39B 4FW5A 4AQYE 3P3CA 4GKKE 3M7NG 3M6AA 3KRNA 4P7AA 5IWAE 4DR4E 2V34A 5JEAB 5IWAI 4LFAI 4DV0I 2XEXA 4JI2I 1Y4UA 2Z5BA 4DV7I 4JI6I 3B78A 4IZJA 1Y6ZA 2PO0A 1BKNA 1Z0GA 2JEBB 4BA2B 3L7ZA 3H1CA 5K36D 2IOPA 4LF6E 2E5LE 1HNWI
chains in the Genus database with same CATH topology
4LCGA 4FW4A 2VESA 4ISAA 3P3GA 4OKGA 4U3BA 4FW6A 3PS1A 4OZEA 4FW7A 3U1YA 1YHCA 3UHMA 1P42A 1YH8A 1XXEA 2IERA 2GO3A 4U3DA 4LCHA 4LCFA 5DRQA 5DROA 2J65A 2JT2A 4MDTA 4MQYA 2O3ZA 2IESA 4J3DA 2GO4A 4IS9A 5DRRA 3P76A 4FW3A 4FW5A 3P3CA 3NZKA 3PS2A 5DRPA 3P3EA 3PS3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LCG A;  4FW4 A;  2VES A;  4ISA A;  3P3G A;  4OKG A;  4U3B A;  4FW6 A;  3PS1 A;  4OZE A;  4FW7 A;  3U1Y A;  1YHC A;  3UHM A;  1P42 A;  1YH8 A;  1XXE A;  2IER A;  2GO3 A;  4U3D A;  4LCH A;  4LCF A;  5DRQ A;  5DRO A;  2J65 A;  2JT2 A;  4MDT A;  4MQY A;  2O3Z A;  2IES A;  4J3D A;  2GO4 A;  4IS9 A;  5DRR A;  3P76 A;  4FW3 A;  4FW5 A;  3P3C A;  3NZK A;  3PS2 A;  5DRP A;  3P3E A;  3PS3 A; 
#chains in the Genus database with same CATH topology
 2UUC E;  1FJG E;  1S16 A;  1OYR A;  4U3B A;  4NXM E;  4JI3 I;  4HAC A;  3J80 C;  1YHC A;  4R1F A;  4LF9 E;  4YHH I;  4FWG A;  5LMU I;  2JE6 B;  3V5R A;  4DR1 I;  4B3M E;  4MU3 A;  4U3D A;  4DR6 E;  4BA1 B;  1I94 I;  1FNM A;  2VQE E;  4JI5 I;  2CZ9 A;  1N34 E;  3B8H A;  3QT6 A;  4MU4 A;  2R42 A;  4GQU A;  4MYT A;  1HR0 I;  4DUY E;  2C38 A;  1ELO A;  5DRP A;  1VI7 A;  3ZKD A;  4DU8 A;  4DUY I;  3V2U C;  4DXL A;  3M85 G;  2NN6 B;  2E1R A;  4DR7 E;  5K36 E;  2NPF A;  4FW6 A;  3D4J A;  4OZE A;  3PYE A;  5FWK A;  2GO3 A;  4LF4 I;  3ZZT A;  2NN6 F;  4PU9 A;  4DPW A;  2LJP A;  3F0N A;  4AID A;  4ZVI A;  2UXC E;  4DR2 E;  2WNR B;  3OTO I;  1XHK A;  3P76 A;  4FN5 A;  5BR8 E;  4IZK B;  5JEA D;  3PS3 A;  4LCG A;  4FW4 A;  4AM3 A;  3M7N D;  1UDO A;  4ISA A;  2O1T A;  1ZM2 A;  1Z0W A;  3P3G A;  1Z5A A;  4IFD E;  4KHP I;  4WUC A;  2JEA A;  4OO1 D;  2NN6 D;  4MYU A;  4N3O A;  2JEB A;  4BA2 A;  1VIS A;  1KVK A;  1WUU A;  4I3H A;  3U1K A;  4JI2 E;  4YY3 I;  2UXC I;  4OO1 B;  3CDI A;  2UUB E;  3OTO E;  3ZZU A;  5BR8 I;  1OYS A;  2IES A;  5EL9 A;  4JI0 I;  1E3P A;  1FWK A;  1FI4 A;  5IT9 Q;  4DV6 E;  2HHH E;  1KTV A;  4DPU A;  2A2C A;  4JV5 I;  1XMQ E;  4JI4 E;  1Z0V A;  1HK7 A;  5C0X B;  1USU A;  1Y4S A;  4QNJ A;  2BM0 A;  2Z5C B;  1IBK I;  2UU9 I;  2UUA E;  1PKP A;  1NZ0 A;  3QT8 A;  1Z0E A;  2UXD I;  2WW4 A;  4JI1 E;  4B3R I;  4OO1 E;  2PO2 A;  2J7K A;  4IFD D;  3T1H E;  2HK3 A;  5FLX C;  4IFD F;  4DV6 I;  1N36 I;  3HKM A;  5JEA E;  1N33 E;  3GCM A;  4DR4 I;  4B3S I;  2EFG A;  2C37 A;  3U1Y A;  4JI3 E;  4B3T I;  2J65 A;  2GQ0 A;  4FWH A;  5FLX Q;  1NHJ A;  4LF7 E;  4NXN E;  5LL6 R;  4DPT A;  1MX0 A;  5K36 B;  4B3S E;  2F4V E;  4YHH E;  4EMD A;  2PO1 B;  2HFU A;  1I94 E;  4USM A;  1NHI A;  3GME A;  4DV1 E;  2BA1 D;  2PNL A;  5DRQ A;  1DAR A;  4MQY A;  4DUZ I;  4DV3 E;  4DPY A;  1S4E A;  4MU1 A;  4JI7 E;  2NN6 C;  2UUB I;  2PNZ A;  2CGE A;  4X65 I;  1KIJ A;  2Z5C A;  2HFS A;  5C0X A;  4PRX A;  2JEA B;  3LTO A;  1H7S A;  2VES A;  3WU6 A;  1XNQ I;  4WUB A;  1H74 A;  3CWV A;  2BR2 B;  3LNU A;  1ZXM A;  4DV1 I;  2ZBK B;  4LF8 I;  1XNR E;  4Z7Y A;  4LFA E;  3WU4 A;  2JT2 A;  1QZR A;  4YY3 E;  4DV4 I;  2C37 B;  3J81 Q;  4GKK I;  4HXZ A;  2BA0 D;  1KKH A;  2O1W A;  2PNM A;  5LMN I;  2E5L I;  2BM1 A;  1HNW E;  3CDJ A;  2C39 A;  3WU3 A;  4OO1 C;  4WUD A;  1XMQ I;  1P42 A;  5C0X F;  4K0K E;  1IBK E;  4FWD A;  4DR5 I;  3K1J A;  4JI8 I;  4JI0 E;  1Y5Y A;  2Q2E B;  2R3V A;  4OX9 I;  1D6T A;  1NHH A;  1RR9 A;  3K85 A;  4X64 E;  4HAC B;  4OX9 E;  3PS2 A;  1FJG I;  2V8P A;  5C0X E;  2UXB E;  1B63 A;  2UUC I;  5GME A;  2VQF I;  5DNX A;  4FW7 A;  2HK2 A;  4DU7 A;  5IT9 C;  1IBL E;  4GKJ E;  2C38 B;  2HKE A;  1B62 A;  1ZM4 A;  4RPF A;  4UTG A;  4GKJ I;  2V2Q A;  1FWL A;  4JI1 I;  4B3T E;  1XMO I;  4JI6 E;  2PO2 B;  5DNL A;  4URL A;  4DV3 I;  3T1Y I;  2GS8 A;  4IS9 A;  4AIM A;  4FW3 A;  4DR2 I;  1R6M A;  1Z0B A;  4JYA I;  2UXB I;  3H4L A;  3P3E A;  1OYP A;  3JAM Q;  1E3H A;  2F4V I;  2AJ4 A;  1UEK A;  4NXM I;  4X62 E;  3PYF A;  1N32 E;  1XNQ E;  1U2R A;  3B82 A;  4X66 I;  4IZK A;  1UDQ A;  1XMO E;  2VF3 A;  4M1K A;  2PO0 B;  1PIE A;  4MDT A;  1HNZ E;  1Y60 A;  1H72 C;  2F1D A;  5GMD A;  1HR0 E;  2X36 A;  5K36 C;  2BR2 A;  5DRR A;  5EKW A;  1J5E E;  4IFD B;  2V2V A;  4MU0 A;  4XTJ A;  3QT7 A;  4X65 E;  1MG7 A;  2X7I A;  4OKG A;  2HHH I;  4JV5 E;  2ZIT A;  4NBQ A;  3UHM A;  1XNR I;  3LPS A;  4PRV A;  4LF4 E;  3QT5 A;  1FKA E;  4LCH A;  4USK A;  4LF8 E;  4LCF A;  2OI2 A;  1H7U A;  5JEA C;  4DR5 E;  2DEI A;  4DV2 E;  4IZJ D;  2UXD E;  4B3R E;  4J3D A;  1K47 A;  1MU5 A;  1Z0T A;  2O1U A;  2DEJ A;  4P52 A;  5LMN E;  4HYM A;  4DV5 I;  2WP8 B;  4LF6 I;  4HY1 A;  3ZZ0 A;  4KHP E;  4DV5 E;  1ZXN A;  4OO1 F;  4JI4 I;  2NN6 A;  5K36 A;  1RRE A;  3ZM7 A;  1Z5C A;  4ED4 A;  1IBM I;  5JEA F;  2IER A;  3DD6 A;  4LOM A;  1IBM E;  2WNR A;  4KQV A;  3K17 A;  5DRO A;  1RHY A;  5A2Q Q;  3T1H I;  2O3Z A;  3P06 A;  2CG9 A;  4AQY I;  4JI8 E;  4BA1 A;  1N36 E;  4LF5 E;  2AE8 A;  3Q1Q A;  1HNX E;  3T1Y E;  1A6F A;  3M85 D;  4LF7 I;  1HNX I;  3GLL A;  5L3J A;  4IFD A;  1IBL I;  3HJC A;  1EI1 A;  3PRY A;  2UU9 E;  4UT4 A;  4DV0 E;  2WP8 A;  2VQF E;  4DR6 I;  1Z5B A;  4FW9 A;  4JG4 A;  2Z5E A;  4DPX A;  5C0X D;  2VQE I;  1UDN A;  4DV7 E;  4LF9 I;  1N0V C;  1N34 I;  5LMU E;  4DR1 E;  4B3M I;  3PYD A;  4LFB I;  2ZM6 I;  4LF5 I;  2CVE A;  4X64 I;  1ZM3 A;  1R6L A;  4LFB E;  3WU5 A;  4QNK A;  1PVG A;  2ZM6 E;  2O1V A;  1N33 I;  3J7A M;  3JAM C;  3NZK A;  2BV3 A;  2GO4 A;  1J5E I;  4JYA E;  4NXN I;  2NN6 E;  2A2D A;  4DR7 I;  3PS1 A;  2PNZ B;  3Q6M A;  3L7Z B;  4LFC I;  1UDS A;  1XXE A;  4LFC E;  4X66 E;  4JI5 E;  3ZKB A;  5K36 F;  1EA6 A;  4JI7 I;  4OO1 A;  3J80 Q;  1OJ4 A;  4DUZ E;  2JE6 A;  3J81 C;  5ELW A;  4DV4 E;  2PO1 A;  4X62 I;  5JEA A;  1USV A;  1N32 I;  2IOQ A;  3B4T A;  1ZM9 A;  1Z0C A;  5A2Q C;  2HKJ A;  3GON A;  4Z7C A;  1YH8 A;  3Q6N A;  1Z59 A;  4LPF A;  2Z5B B;  2UUA I;  1HNZ I;  1H73 A;  4DR3 I;  4IZJ B;  4IFD C;  3PYG A;  4K0K I;  5C0X C;  4DR3 E;  2V2Z A;  1N0U A;  3HUL A;  2BA1 G;  4DV2 I;  3J7A G;  2BA0 G;  2C39 B;  4FW5 A;  4AQY E;  3P3C A;  4GKK E;  3M7N G;  3M6A A;  3KRN A;  4P7A A;  5IWA E;  4DR4 E;  2V34 A;  5JEA B;  5IWA I;  4LFA I;  4DV0 I;  2XEX A;  4JI2 I;  1Y4U A;  2Z5B A;  4DV7 I;  4JI6 I;  3B78 A;  4IZJ A;  1Y6Z A;  2PO0 A;  1BKN A;  1Z0G A;  2JEB B;  4BA2 B;  3L7Z A;  3H1C A;  5K36 D;  2IOP A;  4LF6 E;  2E5L E;  1HNW I; 
#chains in the Genus database with same CATH homology
 4LCG A;  4FW4 A;  2VES A;  4ISA A;  3P3G A;  4OKG A;  4U3B A;  4FW6 A;  3PS1 A;  4OZE A;  4FW7 A;  3U1Y A;  1YHC A;  3UHM A;  1P42 A;  1YH8 A;  1XXE A;  2IER A;  2GO3 A;  4U3D A;  4LCH A;  4LCF A;  5DRQ A;  5DRO A;  2J65 A;  2JT2 A;  4MDT A;  4MQY A;  2O3Z A;  2IES A;  4J3D A;  2GO4 A;  4IS9 A;  5DRR A;  3P76 A;  4FW3 A;  4FW5 A;  3P3C A;  3NZK A;  3PS2 A;  5DRP A;  3P3E A;  3PS3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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