1P42A

Crystal structure of aquifex aeolicus lpxc deacetylase (zinc-inhibited form)
Total Genus 90
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
90
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Crystal Structure of LpxC, a Zinc-Dependent Deacetylase Essential for Endotoxin Biosynthesis
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 90
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2003-04-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1p42A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1p42A02
3PS1A 4FW3A 4LCHA 5DRPA 1YH8A 1XXEA 2IERA 2VESA 4OKGA 3UHMA 3PS2A 3P3GA 4FW5A 2O3ZA 4MQYA 4OZEA 1P42A 4J3DA 4LCFA 4FW4A 4FW6A 3NZKA 2JT2A 4IS9A 4MDTA 5DRRA 2GO4A 4U3DA 5DROA 2GO3A 3P3EA 2J65A 4U3BA 5DRQA 4LCGA 1YHCA 3P3CA 4ISAA 3U1YA 3P76A 3PS3A 4FW7A 2IESA
chains in the Genus database with same CATH superfamily
2VF3A 4ED4A 2PO1A 4JYAE 2PNZA 4NXME 1ELOA 1OYSA 4LFBI 1ZM2A 3M85D 1U2RA 2O3ZA 1Z0WA 3K85A 2F4VE 4LF4E 2CG9A 3D4JA 4OO1D 3Q6MA 4URLA 2JT2A 1HR0I 4IS9A 4PU9A 4Z7CA 2AE8A 2JEAA 3P06A 2PO0A 4IFDF 5K36F 4DV2I 4GQUA 4B3ME 3LPSA 4LF6E 2BM1A 5DRPA 4AIMA 1Z59A 4DR3E 1RHYA 3M7ND 2E5LI 1MG7A 3GMEA 4NXNI 4FW6A 1QZRA 5C0XB 1XMQE 4X64I 1NHHA 2UUAI 4B3SI 4DV7I 3CDJA 2OI2A 1Z0EA 1R6MA 4YY3I 3QT7A 4WUBA 2E5LE 2O1UA 1B62A 4NXNE 2Z5BA 2IESA 3J7AG 4X64E 5C0XE 3B8HA 2BA1G 2UUAE 3L7ZA 1XMOI 4HY1A 4YY3E 4IFDA 2BA0G 5K36A 4USMA 2HHHI 2UXDI 4J3DA 3QT6A 4BA1A 4OO1C 4AM3A 2A2DA 4RPFA 4LF9I 4X65E 5IT9Q 2VQEI 3CWVA 1XMOE 4KHPI 1IBKI 1PKPA 2HHHE 4JV5I 4ISAA 4LF7I 3ZZ0A 2UXDE 3U1YA 4NBQA 2PNLA 2UU9I 2WP8A 1I94I 1OJ4A 4DV3E 2IERA 2VQEE 1NZ0A 3P3GA 1NHJA 4KHPE 1IBKE 3H4LA 4JV5E 4IZKA 4LF7E 1FJGE 3T1YI 2BR2A 4U3DA 4BA1B 2UU9E 1UDSA 3M7NG 2Q2EB 4X66E 2UXCI 4B3RE 3PYFA 1A6FA 4IZJD 1Z5BA 2AJ4A 4IFDE 4DPWA 5K36E 4DPXA 2CVEA 4DU7A 2VESA 3WU5A 4FWGA 3T1HI 1R6LA 3ZM7A 4JI0E 2NN6D 1FNMA 3ZKDA 4HYMA 4DR5I 1N36I 5JEAF 5IT9C 1KVKA 4IZKB 1IBME 1Y5YA 4NXMI 2J65A 3T1HE 1OYRA 3U1KA 3PS3A 4DR5E 1N36E 2BM0A 1HNZI 3PS1A 1XNRI 1YH8A 4WUDA 4Z7YA 3B78A 5C0XA 4JI7I 4B3MI 3PYEA 4FWDA 1B63A 4LFAE 1HNZE 1XNRE 5EL9A 4LF6I 4JI4I 2ZBKB 4DR3I 1N34I 4JI7E 1KKHA 3DD6A 5JEAA 1XMQI 3PYGA 4OO1B 2IOPA 2X36A 4DR4E 4WUCA 1HK7A 1UDOA 4JI4E 4MYUA 1KIJA 2NN6C 4QNJA 1N34E 3QT8A 4FW4A 1FWKA 4DR6I 4JG4A 4GKJI 2GO3A 2R42A 1OYPA 2BV3A 4B3TE 3HKMA 2WW4A 3H1CA 5C0XD 3V2UC 1H7UA 2O1WA 1E3PA 4DR6E 1N32I 2V2VA 1ZM3A 1XHKA 4DUYI 4LCHA 1Z5CA 4GKJE 5JEAB 4OKGA 5LMNE 4X65I 4FN5A 1P42A 1Z0CA 2O1TA 5FLXC 4DR1I 1H72C 3F0NA 1FWLA 3NZKA 1Z0BA 1N32E 2GO4A 1K47A 4DUYE 5GMDA 4DV3I 2C39B 5JEAE 3M85G 4PRXA 4UT4A 1N33E 4DR1E 4OX9E 4BA2A 1FJGI 1IBLE 1Z0GA 4DV5I 1UDQA 2E1RA 4ZVIA 1ZXNA 4YHHI 1EI1A 2ZM6I 2O1VA 4LFCI 4EMDA 1NHIA 4P52A 3HULA 1EA6A 4X66I 4P7AA 2WNRB 3J80Q 2C37B 4B3RI 4OO1F 4DV5E 2EFGA 3WU3A 4YHHE 1Z0TA 4DV0E 2ZM6E 3P3EA 5FWKA 4IFDD 5L3JA 4LFCE 5K36D 5C0XC 4LCGA 1PVGA 4JI0I 1VISA 3LNUA 4USKA 4JI8I 5DNLA 3ZKBA 5A2QQ 3OTOE 4BA2B 3ZZUA 1IBMI 4MU4A 5IWAI 4JI5E 2HKEA 4MQYA 5BR8I 1VI7A 1PIEA 3Q6NA 4DR7I 2NPFA 4FWHA 1FI4A 2HK3A 2UUBI 3J81Q 4JI8E 5ELWA 1HNWI 4IZJB 4X62I 5IWAE 2GS8A 4JI2E 1H74A 2Z5CB 3KRNA 5BR8E 1YHCA 4DR7E 4M1KA 3P76A 4OO1A 2NN6B 2UUBE 4DPUA 1S16A 1HNWE 3QT5A 4LFAI 4X62E 2J7KA 3PYDA 3UHMA 1RR9A 3J80C 1XNQE 3Q1QA 3B82A 1D6TA 4HACB 2HKJA 2HFUA 3GCMA 1H73A 1Y60A 5FLXQ 4DR4I 5LL6R 4AIDA 4IFDC 5K36C 2BA0D 1BKNA 5A2QC 4LF8I 1USUA 1FKAE 1Y6ZA 4DV1I 4KQVA 3WU4A 1N0UA 2C38B 1H7SA 4B3TI 4GKKI 1Y4UA 3J81C 1USVA 4DR2I 1HNXE 2V8PA 4DU8A 3B4TA 4LF8E 1E3HA 4MDTA 4DV1E 2CZ9A 2C39A 4DPTA 4LFBE 1ZM4A 5DRQA 4OO1E 5LMNI 4GKKE 4DR2E 1KTVA 1MU5A 1HR0E 3LTOA 2HFSA 4PRVA 2VQFI 1Z0VA 2HK2A 2JE6B 2R3VA 5LMUI 2LJPA 2PO1B 2PNZB 1Y4SA 4DV2E 2WNRA 1S4EA 2C37A 2NN6F 1N33I 4OX9I 5JEAD 1MX0A 3JAMQ 1IBLI 2VQFE 4LOMA 2IOQA 1N0VC 5LMUE 3GONA 4MYTA 3K17A 2V2ZA 2JEAB 4HXZA 2A2CA 2PO0B 1ZM9A 1RREA 4B3SE 3M6AA 4DV7E 4DV0I 1UDNA 4UTGA 3PS2A 4FW5A 4JI6I 2JEBB 4DV4I 4LCFA 2PO2A 2ZITA 1UEKA 3K1JA 4XTJA 4IZJA 5DRRA 5DROA 3OTOI 4LF5I 2Z5CA 4R1FA 2F1DA 4JI1I 4JI5I 1J5EI 4JI6E 3CDIA 2UUCI 3ZZTA 2NN6A 4DV4E 4I3HA 4MU3A 4FW9A 4AQYI 2Z5BB 4LF9E 4FW3A 4LF5E 2PNMA 2V2QA 4JI1E 4MU1A 4HACA 3L7ZB 1J5EE 3JAMC 4JI2I 3PRYA 2UUCE 4IFDB 5K36B 2UXBI 5JEAC 3WU6A 3GLLA 3J7AM 4DV6I 4AQYE 1ZXMA 1I94E 2PO2B 1WUUA 4JI3I 1XNQI 5C0XF 4DUZI 2JEBA 3T1YE 4N3OA 4FW7A 5GMEA 2UXBE 2C38A 4DV6E 5EKWA 4MU0A 1XXEA 5DNXA 2GQ0A 2WP8B 2UXCE 4OZEA 4K0KI 4JI3E 4DUZE 2XEXA 3HJCA 4QNKA 1DARA 2Z5EA 4JYAI 4LPFA 2CGEA 2BR2B 2DEIA 2NN6E 2BA1D 4U3BA 4DXLA 2F4VI 4K0KE 2DEJA 2V34A 4LF4I 3P3CA 1Z5AA 1HNXI 4DPYA 3V5RA 2JE6A 2X7IA
chains in the Genus database with same CATH topology
3PS1A 4FW3A 4LCHA 5DRPA 1YH8A 1XXEA 2IERA 2VESA 4OKGA 3UHMA 3PS2A 3P3GA 4FW5A 2O3ZA 4MQYA 4OZEA 1P42A 4J3DA 4LCFA 4FW4A 4FW6A 3NZKA 2JT2A 4IS9A 4MDTA 5DRRA 2GO4A 4U3DA 5DROA 2GO3A 3P3EA 2J65A 4U3BA 5DRQA 4LCGA 1YHCA 3P3CA 4ISAA 3U1YA 3P76A 3PS3A 4FW7A 2IESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PS1 A;  4FW3 A;  4LCH A;  5DRP A;  1YH8 A;  1XXE A;  2IER A;  2VES A;  4OKG A;  3UHM A;  3PS2 A;  3P3G A;  4FW5 A;  2O3Z A;  4MQY A;  4OZE A;  1P42 A;  4J3D A;  4LCF A;  4FW4 A;  4FW6 A;  3NZK A;  2JT2 A;  4IS9 A;  4MDT A;  5DRR A;  2GO4 A;  4U3D A;  5DRO A;  2GO3 A;  3P3E A;  2J65 A;  4U3B A;  5DRQ A;  4LCG A;  1YHC A;  3P3C A;  4ISA A;  3U1Y A;  3P76 A;  3PS3 A;  4FW7 A;  2IES A; 
#chains in the Genus database with same CATH topology
 2VF3 A;  4ED4 A;  2PO1 A;  4JYA E;  2PNZ A;  4NXM E;  1ELO A;  1OYS A;  4LFB I;  1ZM2 A;  3M85 D;  1U2R A;  2O3Z A;  1Z0W A;  3K85 A;  2F4V E;  4LF4 E;  2CG9 A;  3D4J A;  4OO1 D;  3Q6M A;  4URL A;  2JT2 A;  1HR0 I;  4IS9 A;  4PU9 A;  4Z7C A;  2AE8 A;  2JEA A;  3P06 A;  2PO0 A;  4IFD F;  5K36 F;  4DV2 I;  4GQU A;  4B3M E;  3LPS A;  4LF6 E;  2BM1 A;  5DRP A;  4AIM A;  1Z59 A;  4DR3 E;  1RHY A;  3M7N D;  2E5L I;  1MG7 A;  3GME A;  4NXN I;  4FW6 A;  1QZR A;  5C0X B;  1XMQ E;  4X64 I;  1NHH A;  2UUA I;  4B3S I;  4DV7 I;  3CDJ A;  2OI2 A;  1Z0E A;  1R6M A;  4YY3 I;  3QT7 A;  4WUB A;  2E5L E;  2O1U A;  1B62 A;  4NXN E;  2Z5B A;  2IES A;  3J7A G;  4X64 E;  5C0X E;  3B8H A;  2BA1 G;  2UUA E;  3L7Z A;  1XMO I;  4HY1 A;  4YY3 E;  4IFD A;  2BA0 G;  5K36 A;  4USM A;  2HHH I;  2UXD I;  4J3D A;  3QT6 A;  4BA1 A;  4OO1 C;  4AM3 A;  2A2D A;  4RPF A;  4LF9 I;  4X65 E;  5IT9 Q;  2VQE I;  3CWV A;  1XMO E;  4KHP I;  1IBK I;  1PKP A;  2HHH E;  4JV5 I;  4ISA A;  4LF7 I;  3ZZ0 A;  2UXD E;  3U1Y A;  4NBQ A;  2PNL A;  2UU9 I;  2WP8 A;  1I94 I;  1OJ4 A;  4DV3 E;  2IER A;  2VQE E;  1NZ0 A;  3P3G A;  1NHJ A;  4KHP E;  1IBK E;  3H4L A;  4JV5 E;  4IZK A;  4LF7 E;  1FJG E;  3T1Y I;  2BR2 A;  4U3D A;  4BA1 B;  2UU9 E;  1UDS A;  3M7N G;  2Q2E B;  4X66 E;  2UXC I;  4B3R E;  3PYF A;  1A6F A;  4IZJ D;  1Z5B A;  2AJ4 A;  4IFD E;  4DPW A;  5K36 E;  4DPX A;  2CVE A;  4DU7 A;  2VES A;  3WU5 A;  4FWG A;  3T1H I;  1R6L A;  3ZM7 A;  4JI0 E;  2NN6 D;  1FNM A;  3ZKD A;  4HYM A;  4DR5 I;  1N36 I;  5JEA F;  5IT9 C;  1KVK A;  4IZK B;  1IBM E;  1Y5Y A;  4NXM I;  2J65 A;  3T1H E;  1OYR A;  3U1K A;  3PS3 A;  4DR5 E;  1N36 E;  2BM0 A;  1HNZ I;  3PS1 A;  1XNR I;  1YH8 A;  4WUD A;  4Z7Y A;  3B78 A;  5C0X A;  4JI7 I;  4B3M I;  3PYE A;  4FWD A;  1B63 A;  4LFA E;  1HNZ E;  1XNR E;  5EL9 A;  4LF6 I;  4JI4 I;  2ZBK B;  4DR3 I;  1N34 I;  4JI7 E;  1KKH A;  3DD6 A;  5JEA A;  1XMQ I;  3PYG A;  4OO1 B;  2IOP A;  2X36 A;  4DR4 E;  4WUC A;  1HK7 A;  1UDO A;  4JI4 E;  4MYU A;  1KIJ A;  2NN6 C;  4QNJ A;  1N34 E;  3QT8 A;  4FW4 A;  1FWK A;  4DR6 I;  4JG4 A;  4GKJ I;  2GO3 A;  2R42 A;  1OYP A;  2BV3 A;  4B3T E;  3HKM A;  2WW4 A;  3H1C A;  5C0X D;  3V2U C;  1H7U A;  2O1W A;  1E3P A;  4DR6 E;  1N32 I;  2V2V A;  1ZM3 A;  1XHK A;  4DUY I;  4LCH A;  1Z5C A;  4GKJ E;  5JEA B;  4OKG A;  5LMN E;  4X65 I;  4FN5 A;  1P42 A;  1Z0C A;  2O1T A;  5FLX C;  4DR1 I;  1H72 C;  3F0N A;  1FWL A;  3NZK A;  1Z0B A;  1N32 E;  2GO4 A;  1K47 A;  4DUY E;  5GMD A;  4DV3 I;  2C39 B;  5JEA E;  3M85 G;  4PRX A;  4UT4 A;  1N33 E;  4DR1 E;  4OX9 E;  4BA2 A;  1FJG I;  1IBL E;  1Z0G A;  4DV5 I;  1UDQ A;  2E1R A;  4ZVI A;  1ZXN A;  4YHH I;  1EI1 A;  2ZM6 I;  2O1V A;  4LFC I;  4EMD A;  1NHI A;  4P52 A;  3HUL A;  1EA6 A;  4X66 I;  4P7A A;  2WNR B;  3J80 Q;  2C37 B;  4B3R I;  4OO1 F;  4DV5 E;  2EFG A;  3WU3 A;  4YHH E;  1Z0T A;  4DV0 E;  2ZM6 E;  3P3E A;  5FWK A;  4IFD D;  5L3J A;  4LFC E;  5K36 D;  5C0X C;  4LCG A;  1PVG A;  4JI0 I;  1VIS A;  3LNU A;  4USK A;  4JI8 I;  5DNL A;  3ZKB A;  5A2Q Q;  3OTO E;  4BA2 B;  3ZZU A;  1IBM I;  4MU4 A;  5IWA I;  4JI5 E;  2HKE A;  4MQY A;  5BR8 I;  1VI7 A;  1PIE A;  3Q6N A;  4DR7 I;  2NPF A;  4FWH A;  1FI4 A;  2HK3 A;  2UUB I;  3J81 Q;  4JI8 E;  5ELW A;  1HNW I;  4IZJ B;  4X62 I;  5IWA E;  2GS8 A;  4JI2 E;  1H74 A;  2Z5C B;  3KRN A;  5BR8 E;  1YHC A;  4DR7 E;  4M1K A;  3P76 A;  4OO1 A;  2NN6 B;  2UUB E;  4DPU A;  1S16 A;  1HNW E;  3QT5 A;  4LFA I;  4X62 E;  2J7K A;  3PYD A;  3UHM A;  1RR9 A;  3J80 C;  1XNQ E;  3Q1Q A;  3B82 A;  1D6T A;  4HAC B;  2HKJ A;  2HFU A;  3GCM A;  1H73 A;  1Y60 A;  5FLX Q;  4DR4 I;  5LL6 R;  4AID A;  4IFD C;  5K36 C;  2BA0 D;  1BKN A;  5A2Q C;  4LF8 I;  1USU A;  1FKA E;  1Y6Z A;  4DV1 I;  4KQV A;  3WU4 A;  1N0U A;  2C38 B;  1H7S A;  4B3T I;  4GKK I;  1Y4U A;  3J81 C;  1USV A;  4DR2 I;  1HNX E;  2V8P A;  4DU8 A;  3B4T A;  4LF8 E;  1E3H A;  4MDT A;  4DV1 E;  2CZ9 A;  2C39 A;  4DPT A;  4LFB E;  1ZM4 A;  5DRQ A;  4OO1 E;  5LMN I;  4GKK E;  4DR2 E;  1KTV A;  1MU5 A;  1HR0 E;  3LTO A;  2HFS A;  4PRV A;  2VQF I;  1Z0V A;  2HK2 A;  2JE6 B;  2R3V A;  5LMU I;  2LJP A;  2PO1 B;  2PNZ B;  1Y4S A;  4DV2 E;  2WNR A;  1S4E A;  2C37 A;  2NN6 F;  1N33 I;  4OX9 I;  5JEA D;  1MX0 A;  3JAM Q;  1IBL I;  2VQF E;  4LOM A;  2IOQ A;  1N0V C;  5LMU E;  3GON A;  4MYT A;  3K17 A;  2V2Z A;  2JEA B;  4HXZ A;  2A2C A;  2PO0 B;  1ZM9 A;  1RRE A;  4B3S E;  3M6A A;  4DV7 E;  4DV0 I;  1UDN A;  4UTG A;  3PS2 A;  4FW5 A;  4JI6 I;  2JEB B;  4DV4 I;  4LCF A;  2PO2 A;  2ZIT A;  1UEK A;  3K1J A;  4XTJ A;  4IZJ A;  5DRR A;  5DRO A;  3OTO I;  4LF5 I;  2Z5C A;  4R1F A;  2F1D A;  4JI1 I;  4JI5 I;  1J5E I;  4JI6 E;  3CDI A;  2UUC I;  3ZZT A;  2NN6 A;  4DV4 E;  4I3H A;  4MU3 A;  4FW9 A;  4AQY I;  2Z5B B;  4LF9 E;  4FW3 A;  4LF5 E;  2PNM A;  2V2Q A;  4JI1 E;  4MU1 A;  4HAC A;  3L7Z B;  1J5E E;  3JAM C;  4JI2 I;  3PRY A;  2UUC E;  4IFD B;  5K36 B;  2UXB I;  5JEA C;  3WU6 A;  3GLL A;  3J7A M;  4DV6 I;  4AQY E;  1ZXM A;  1I94 E;  2PO2 B;  1WUU A;  4JI3 I;  1XNQ I;  5C0X F;  4DUZ I;  2JEB A;  3T1Y E;  4N3O A;  4FW7 A;  5GME A;  2UXB E;  2C38 A;  4DV6 E;  5EKW A;  4MU0 A;  1XXE A;  5DNX A;  2GQ0 A;  2WP8 B;  2UXC E;  4OZE A;  4K0K I;  4JI3 E;  4DUZ E;  2XEX A;  3HJC A;  4QNK A;  1DAR A;  2Z5E A;  4JYA I;  4LPF A;  2CGE A;  2BR2 B;  2DEI A;  2NN6 E;  2BA1 D;  4U3B A;  4DXL A;  2F4V I;  4K0K E;  2DEJ A;  2V34 A;  4LF4 I;  3P3C A;  1Z5A A;  1HNX I;  4DPY A;  3V5R A;  2JE6 A;  2X7I A; 
#chains in the Genus database with same CATH homology
 3PS1 A;  4FW3 A;  4LCH A;  5DRP A;  1YH8 A;  1XXE A;  2IER A;  2VES A;  4OKG A;  3UHM A;  3PS2 A;  3P3G A;  4FW5 A;  2O3Z A;  4MQY A;  4OZE A;  1P42 A;  4J3D A;  4LCF A;  4FW4 A;  4FW6 A;  3NZK A;  2JT2 A;  4IS9 A;  4MDT A;  5DRR A;  2GO4 A;  4U3D A;  5DRO A;  2GO3 A;  3P3E A;  2J65 A;  4U3B A;  5DRQ A;  4LCG A;  1YHC A;  3P3C A;  4ISA A;  3U1Y A;  3P76 A;  3PS3 A;  4FW7 A;  2IES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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