2F1DA

X-ray structure of imidazoleglycerol-phosphate dehydratase
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
183
structure length
183
Chain Sequence
GRIGEVKRVTKETNVSVKINLDGTGVADSSSGIPFLDHMLDQLASHGLFDVHVRATGDVHIDDHHTNEDIALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGENSHHIIEATFKAFARALRQATETDPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of imidazoleglycerol-phosphate dehydratase.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
molecule keywords Imidazoleglycerol-phosphate dehydratase 1
total genus 54
structure length 183
sequence length 183
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2005-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 2f1dA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 2f1dA02
4QNKA 5EL9A 5EKWA 4GQUA 4MU4A 4LPFA 4QNJA 2AE8A 4MU1A 5DNLA 5ELWA 2F1DA 1RHYA 4MU0A 5DNXA 4LOMA 4MU3A
chains in the Genus database with same CATH superfamily
4BA1A 2O1TA 2NN6F 2IOQA 4FW3A 1RREA 5DNLA 4JI1I 5EKWA 4IS9A 4JI1E 5K36E 2CGEA 1IBMI 4USMA 1H73A 2UU9E 5GMDA 4JV5E 1Z0BA 3PRYA 4X64E 5LMNE 2A2CA 1ZXMA 3H1CA 4M1KA 2JEAB 1R6MA 4YHHI 3PYEA 4OZEA 1EA6A 2BA0D 2BM1A 1FWKA 4MDTA 2AJ4A 1ZM2A 2AE8A 4URLA 2E5LI 2UXBE 4FWHA 1YHCA 1XMQI 1Y4UA 2BM0A 2HK3A 3Q6MA 2UXDI 1WUUA 1Z0GA 4U3DA 2IOPA 2C38B 2ZM6I 1DARA 4ISAA 4FW7A 3T1YI 4LF9E 1OYRA 3WU3A 5C0XE 2UXCI 4FW9A 4LFAE 1XNQE 1HNZE 4FN5A 3V5RA 2PO2B 4KHPI 4IZJB 4JI4E 2C39A 4OO1A 2Z5BB 1USVA 4B3MI 2PO2A 2E5LE 4MYTA 1S4EA 3P3GA 3PYFA 4DR5I 4JI8E 4EMDA 5A2QC 2BA1G 2JT2A 4LF9I 3M7ND 2JEBB 4DPXA 1XMQE 1NHIA 4IFDE 2Z5CB 4WUDA 4J3DA 1N36E 3M7NG 3LPSA 2NN6C 4YY3E 2HHHI 5K36D 1BKNA 2VQEE 1PKPA 2IESA 4DU8A 2PNZB 4LF5I 1N0VC 4DR2I 3PS2A 1ZM3A 2JEAA 3U1KA 4B3SI 4DR4I 1HNWI 4FWGA 2ZBKB 3T1HI 3QT6A 2C38A 4U3BA 2CVEA 3QT8A 4GKJI 4DV6I 4IZJA 3J80Q 3U1YA 2C39B 4LCHA 3GCMA 4LF7I 4DPWA 4AIDA 3CWVA 1PIEA 4N3OA 1FNMA 5K36C 2V8PA 2CZ9A 3B8HA 4DV3I 4BA2B 2BV3A 4PRXA 4LF5E 2C37A 3V2UC 1S16A 5EL9A 2PNLA 2V2VA 3GONA 3B78A 3UHMA 4P7AA 4DXLA 1MG7A 2WNRA 2GO4A 4DR3E 4K0KE 4JI7E 4DV0I 2CG9A 4B3SE 1XXEA 3F0NA 4P52A 2V2QA 2GQ0A 4B3RI 1P42A 1B63A 3QT7A 3ZZ0A 1VI7A 4LF7E 1XNQI 1OJ4A 1E3HA 4DV1I 2UU9I 2BR2B 4JI0I 4QNKA 5A2QQ 2PNMA 3PYDA 4OO1F 3ZM7A 3K17A 1H7UA 1Y60A 5LL6R 4JI7I 1E3PA 2R42A 1Z0WA 4JI8I 1D6TA 4BA1B 1USUA 1N32I 2HK2A 5JEAE 3ZZUA 4DV6E 4HACB 1I94E 1KIJA 5FLXQ 1IBME 4LF8E 3HKMA 4KQVA 4FW4A 2HFSA 4MU0A 2ZITA 4AQYE 4HXZA 4B3RE 4OKGA 4LPFA 1ELOA 5DNXA 2NPFA 2UXCE 4IZKB 2NN6A 4Z7CA 3M6AA 3ZZTA 2F4VI 4WUBA 2GS8A 2HKJA 4JI0E 1R6LA 2F4VE 4OO1D 5JEAC 3T1HE 5IWAE 4DR7E 2VF3A 3NZKA 4JI3E 3PS3A 4DR3I 3JAMC 4MU4A 1RHYA 3CDJA 4DV3E 4X62E 4DPUA 4X62I 1H74A 4JI2I 3J7AG 2O1WA 4KHPE 2OI2A 4IFDA 1N36I 4LCGA 2PO1B 2WP8A 2DEIA 5DRRA 5JEAD 4MU1A 5FWKA 4RPFA 4NXMI 2PO1A 2JE6B 4B3TE 1UDNA 4DV0E 1IBLI 2VQFI 3JAMQ 3J7AM 4JI6I 2PNZA 1HNWE 5IWAI 4DR7I 2X7IA 4LF6E 1N32E 1XMOE 5C0XB 4LF6I 4FW6A 5DROA 1KTVA 1N33I 2IERA 2J7KA 2UXDE 4DR6E 1HR0E 3K85A 4YY3I 1Z0TA 4UTGA 4MQYA 2Z5BA 1FJGE 3PYGA 5LMUE 4HY1A 3LTOA 2HFUA 5JEAA 4GKJE 2NN6B 4AIMA 3P76A 4IZJD 4LFBE 2GO3A 4DUYI 1UDSA 4IFDB 4GKKE 4LFBI 4OO1B 4DV2E 4R1FA 1Z5AA 2VQFE 1B62A 1EI1A 4PU9A 2UUAI 4AQYI 4XTJA 3OTOE 1FKAE 3Q6NA 2O1UA 2WP8B 2ZM6E 5K36A 3P06A 2XEXA 5IT9C 2VESA 4DPTA 2C37B 4GQUA 4USKA 4Z7YA 1HR0I 5GMEA 1FI4A 4DR1I 3PS1A 4JI5I 4JV5I 4JI5E 3DD6A 5K36B 1OYSA 1Z0CA 1KVKA 4AM3A 2BA0G 4MYUA 1FJGI 4LFCE 4DV7E 3ZKDA 4DR2E 4IFDF 5L3JA 2UUAE 1Y6ZA 3OTOI 4LCFA 2UUCI 1H72C 4I3HA 1I94I 4FW5A 1N33E 3Q1QA 1OYPA 2WW4A 1Y4SA 3QT5A 3L7ZB 3J81C 1Y5YA 1PVGA 4JYAE 1UDQA 4NXNI 4BA2A 5JEAB 3H4LA 4NXNE 4MU3A 4NXME 2E1RA 4DV5I 1KKHA 5LMUI 4OO1C 2LJPA 1A6FA 5DRPA 5C0XF 4JI6E 1Z5CA 2JEBA 2V34A 1N34E 3J80C 2F1DA 4DV4I 4JI3I 4LFCI 4DV4E 2UXBI 1MU5A 4HYMA 3WU5A 1U2RA 3HULA 1XNRI 1J5EE 4LOMA 4HACA 2R3VA 4DPYA 4DR5E 3WU6A 2BA1D 2J65A 4IZKA 4JI2E 1HNXI 3P3EA 1ZXNA 2Q2EB 3GMEA 4FWDA 4QNJA 2Z5CA 1IBKE 5BR8E 2WNRB 3K1JA 5C0XC 1ZM4A 5C0XA 4WUCA 5IT9Q 2O3ZA 3L7ZA 4DV2I 1H7SA 1NHJA 3M85D 1XNRE 3CDIA 1FWLA 2JE6A 2X36A 2Z5EA 1HK7A 4X66E 4X66I 5K36F 4DR4E 1XMOI 2PO0A 1RR9A 3ZKBA 3M85G 1NHHA 4LF4I 1Z59A 3P3CA 1NZ0A 1J5EI 4LF4E 4X65I 4DV1E 1QZRA 2EFGA 3D4JA 4UT4A 1MX0A 1UDOA 1Z5BA 5LMNI 2PO0B 1XHKA 1Z0EA 2O1VA 4IFDC 2DEJA 3KRNA 1YH8A 2VQEI 4LFAI 4DV7I 1IBLE 3GLLA 1HNZI 1IBKI 5ELWA 1VISA 3J81Q 4DV5E 2UUBE 3B82A 4NBQA 3HJCA 2UUBI 1ZM9A 4IFDD 4ED4A 3B4TA 5DRQA 5FLXC 2UUCE 1Z0VA 4DUYE 4GKKI 1UEKA 4DR6I 3WU4A 4K0KI 4LF8I 1K47A 1N0UA 2HKEA 2NN6E 4JYAI 4DUZE 4DUZI 3T1YE 4OO1E 4DU7A 2BR2A 2NN6D 1HNXE 4YHHE 4X65E 2V2ZA 4DR1E 2A2DA 5JEAF 5BR8I 4JI4I 4X64I 1N34I 3LNUA 5C0XD 2HHHE 4OX9E 4B3ME 4OX9I 4ZVIA 4JG4A 4PRVA 4B3TI
chains in the Genus database with same CATH topology
4QNKA 5EL9A 5EKWA 4GQUA 4MU4A 4LPFA 4QNJA 2AE8A 4MU1A 5DNLA 5ELWA 2F1DA 1RHYA 4MU0A 5DNXA 4LOMA 4MU3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QNK A;  5EL9 A;  5EKW A;  4GQU A;  4MU4 A;  4LPF A;  4QNJ A;  2AE8 A;  4MU1 A;  5DNL A;  5ELW A;  2F1D A;  1RHY A;  4MU0 A;  5DNX A;  4LOM A;  4MU3 A; 
#chains in the Genus database with same CATH topology
 4BA1 A;  2O1T A;  2NN6 F;  2IOQ A;  4FW3 A;  1RRE A;  5DNL A;  4JI1 I;  5EKW A;  4IS9 A;  4JI1 E;  5K36 E;  2CGE A;  1IBM I;  4USM A;  1H73 A;  2UU9 E;  5GMD A;  4JV5 E;  1Z0B A;  3PRY A;  4X64 E;  5LMN E;  2A2C A;  1ZXM A;  3H1C A;  4M1K A;  2JEA B;  1R6M A;  4YHH I;  3PYE A;  4OZE A;  1EA6 A;  2BA0 D;  2BM1 A;  1FWK A;  4MDT A;  2AJ4 A;  1ZM2 A;  2AE8 A;  4URL A;  2E5L I;  2UXB E;  4FWH A;  1YHC A;  1XMQ I;  1Y4U A;  2BM0 A;  2HK3 A;  3Q6M A;  2UXD I;  1WUU A;  1Z0G A;  4U3D A;  2IOP A;  2C38 B;  2ZM6 I;  1DAR A;  4ISA A;  4FW7 A;  3T1Y I;  4LF9 E;  1OYR A;  3WU3 A;  5C0X E;  2UXC I;  4FW9 A;  4LFA E;  1XNQ E;  1HNZ E;  4FN5 A;  3V5R A;  2PO2 B;  4KHP I;  4IZJ B;  4JI4 E;  2C39 A;  4OO1 A;  2Z5B B;  1USV A;  4B3M I;  2PO2 A;  2E5L E;  4MYT A;  1S4E A;  3P3G A;  3PYF A;  4DR5 I;  4JI8 E;  4EMD A;  5A2Q C;  2BA1 G;  2JT2 A;  4LF9 I;  3M7N D;  2JEB B;  4DPX A;  1XMQ E;  1NHI A;  4IFD E;  2Z5C B;  4WUD A;  4J3D A;  1N36 E;  3M7N G;  3LPS A;  2NN6 C;  4YY3 E;  2HHH I;  5K36 D;  1BKN A;  2VQE E;  1PKP A;  2IES A;  4DU8 A;  2PNZ B;  4LF5 I;  1N0V C;  4DR2 I;  3PS2 A;  1ZM3 A;  2JEA A;  3U1K A;  4B3S I;  4DR4 I;  1HNW I;  4FWG A;  2ZBK B;  3T1H I;  3QT6 A;  2C38 A;  4U3B A;  2CVE A;  3QT8 A;  4GKJ I;  4DV6 I;  4IZJ A;  3J80 Q;  3U1Y A;  2C39 B;  4LCH A;  3GCM A;  4LF7 I;  4DPW A;  4AID A;  3CWV A;  1PIE A;  4N3O A;  1FNM A;  5K36 C;  2V8P A;  2CZ9 A;  3B8H A;  4DV3 I;  4BA2 B;  2BV3 A;  4PRX A;  4LF5 E;  2C37 A;  3V2U C;  1S16 A;  5EL9 A;  2PNL A;  2V2V A;  3GON A;  3B78 A;  3UHM A;  4P7A A;  4DXL A;  1MG7 A;  2WNR A;  2GO4 A;  4DR3 E;  4K0K E;  4JI7 E;  4DV0 I;  2CG9 A;  4B3S E;  1XXE A;  3F0N A;  4P52 A;  2V2Q A;  2GQ0 A;  4B3R I;  1P42 A;  1B63 A;  3QT7 A;  3ZZ0 A;  1VI7 A;  4LF7 E;  1XNQ I;  1OJ4 A;  1E3H A;  4DV1 I;  2UU9 I;  2BR2 B;  4JI0 I;  4QNK A;  5A2Q Q;  2PNM A;  3PYD A;  4OO1 F;  3ZM7 A;  3K17 A;  1H7U A;  1Y60 A;  5LL6 R;  4JI7 I;  1E3P A;  2R42 A;  1Z0W A;  4JI8 I;  1D6T A;  4BA1 B;  1USU A;  1N32 I;  2HK2 A;  5JEA E;  3ZZU A;  4DV6 E;  4HAC B;  1I94 E;  1KIJ A;  5FLX Q;  1IBM E;  4LF8 E;  3HKM A;  4KQV A;  4FW4 A;  2HFS A;  4MU0 A;  2ZIT A;  4AQY E;  4HXZ A;  4B3R E;  4OKG A;  4LPF A;  1ELO A;  5DNX A;  2NPF A;  2UXC E;  4IZK B;  2NN6 A;  4Z7C A;  3M6A A;  3ZZT A;  2F4V I;  4WUB A;  2GS8 A;  2HKJ A;  4JI0 E;  1R6L A;  2F4V E;  4OO1 D;  5JEA C;  3T1H E;  5IWA E;  4DR7 E;  2VF3 A;  3NZK A;  4JI3 E;  3PS3 A;  4DR3 I;  3JAM C;  4MU4 A;  1RHY A;  3CDJ A;  4DV3 E;  4X62 E;  4DPU A;  4X62 I;  1H74 A;  4JI2 I;  3J7A G;  2O1W A;  4KHP E;  2OI2 A;  4IFD A;  1N36 I;  4LCG A;  2PO1 B;  2WP8 A;  2DEI A;  5DRR A;  5JEA D;  4MU1 A;  5FWK A;  4RPF A;  4NXM I;  2PO1 A;  2JE6 B;  4B3T E;  1UDN A;  4DV0 E;  1IBL I;  2VQF I;  3JAM Q;  3J7A M;  4JI6 I;  2PNZ A;  1HNW E;  5IWA I;  4DR7 I;  2X7I A;  4LF6 E;  1N32 E;  1XMO E;  5C0X B;  4LF6 I;  4FW6 A;  5DRO A;  1KTV A;  1N33 I;  2IER A;  2J7K A;  2UXD E;  4DR6 E;  1HR0 E;  3K85 A;  4YY3 I;  1Z0T A;  4UTG A;  4MQY A;  2Z5B A;  1FJG E;  3PYG A;  5LMU E;  4HY1 A;  3LTO A;  2HFU A;  5JEA A;  4GKJ E;  2NN6 B;  4AIM A;  3P76 A;  4IZJ D;  4LFB E;  2GO3 A;  4DUY I;  1UDS A;  4IFD B;  4GKK E;  4LFB I;  4OO1 B;  4DV2 E;  4R1F A;  1Z5A A;  2VQF E;  1B62 A;  1EI1 A;  4PU9 A;  2UUA I;  4AQY I;  4XTJ A;  3OTO E;  1FKA E;  3Q6N A;  2O1U A;  2WP8 B;  2ZM6 E;  5K36 A;  3P06 A;  2XEX A;  5IT9 C;  2VES A;  4DPT A;  2C37 B;  4GQU A;  4USK A;  4Z7Y A;  1HR0 I;  5GME A;  1FI4 A;  4DR1 I;  3PS1 A;  4JI5 I;  4JV5 I;  4JI5 E;  3DD6 A;  5K36 B;  1OYS A;  1Z0C A;  1KVK A;  4AM3 A;  2BA0 G;  4MYU A;  1FJG I;  4LFC E;  4DV7 E;  3ZKD A;  4DR2 E;  4IFD F;  5L3J A;  2UUA E;  1Y6Z A;  3OTO I;  4LCF A;  2UUC I;  1H72 C;  4I3H A;  1I94 I;  4FW5 A;  1N33 E;  3Q1Q A;  1OYP A;  2WW4 A;  1Y4S A;  3QT5 A;  3L7Z B;  3J81 C;  1Y5Y A;  1PVG A;  4JYA E;  1UDQ A;  4NXN I;  4BA2 A;  5JEA B;  3H4L A;  4NXN E;  4MU3 A;  4NXM E;  2E1R A;  4DV5 I;  1KKH A;  5LMU I;  4OO1 C;  2LJP A;  1A6F A;  5DRP A;  5C0X F;  4JI6 E;  1Z5C A;  2JEB A;  2V34 A;  1N34 E;  3J80 C;  2F1D A;  4DV4 I;  4JI3 I;  4LFC I;  4DV4 E;  2UXB I;  1MU5 A;  4HYM A;  3WU5 A;  1U2R A;  3HUL A;  1XNR I;  1J5E E;  4LOM A;  4HAC A;  2R3V A;  4DPY A;  4DR5 E;  3WU6 A;  2BA1 D;  2J65 A;  4IZK A;  4JI2 E;  1HNX I;  3P3E A;  1ZXN A;  2Q2E B;  3GME A;  4FWD A;  4QNJ A;  2Z5C A;  1IBK E;  5BR8 E;  2WNR B;  3K1J A;  5C0X C;  1ZM4 A;  5C0X A;  4WUC A;  5IT9 Q;  2O3Z A;  3L7Z A;  4DV2 I;  1H7S A;  1NHJ A;  3M85 D;  1XNR E;  3CDI A;  1FWL A;  2JE6 A;  2X36 A;  2Z5E A;  1HK7 A;  4X66 E;  4X66 I;  5K36 F;  4DR4 E;  1XMO I;  2PO0 A;  1RR9 A;  3ZKB A;  3M85 G;  1NHH A;  4LF4 I;  1Z59 A;  3P3C A;  1NZ0 A;  1J5E I;  4LF4 E;  4X65 I;  4DV1 E;  1QZR A;  2EFG A;  3D4J A;  4UT4 A;  1MX0 A;  1UDO A;  1Z5B A;  5LMN I;  2PO0 B;  1XHK A;  1Z0E A;  2O1V A;  4IFD C;  2DEJ A;  3KRN A;  1YH8 A;  2VQE I;  4LFA I;  4DV7 I;  1IBL E;  3GLL A;  1HNZ I;  1IBK I;  5ELW A;  1VIS A;  3J81 Q;  4DV5 E;  2UUB E;  3B82 A;  4NBQ A;  3HJC A;  2UUB I;  1ZM9 A;  4IFD D;  4ED4 A;  3B4T A;  5DRQ A;  5FLX C;  2UUC E;  1Z0V A;  4DUY E;  4GKK I;  1UEK A;  4DR6 I;  3WU4 A;  4K0K I;  4LF8 I;  1K47 A;  1N0U A;  2HKE A;  2NN6 E;  4JYA I;  4DUZ E;  4DUZ I;  3T1Y E;  4OO1 E;  4DU7 A;  2BR2 A;  2NN6 D;  1HNX E;  4YHH E;  4X65 E;  2V2Z A;  4DR1 E;  2A2D A;  5JEA F;  5BR8 I;  4JI4 I;  4X64 I;  1N34 I;  3LNU A;  5C0X D;  2HHH E;  4OX9 E;  4B3M E;  4OX9 I;  4ZVI A;  4JG4 A;  4PRV A;  4B3T I; 
#chains in the Genus database with same CATH homology
 4QNK A;  5EL9 A;  5EKW A;  4GQU A;  4MU4 A;  4LPF A;  4QNJ A;  2AE8 A;  4MU1 A;  5DNL A;  5ELW A;  2F1D A;  1RHY A;  4MU0 A;  5DNX A;  4LOM A;  4MU3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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