4FW4A

Crystal structure of the lpxc in complex with n-[(1s,2r)-2-hydroxy-1-(hydroxycarbamoyl)propyl]-4-(4-phenylbuta-1,3-diyn-1-yl)benzamide inhibitor
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
300
structure length
300
Chain Sequence
b'AMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Crystal Structure of the LpxC
rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase/hydrolase inhibitor
total genus 89
structure length 300
sequence length 300
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4fw4A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4fw4A02
2IESA 1YH8A 2J65A 4FW4A 4FW7A 5DRQA 3NZKA 4ISAA 4J3DA 4U3DA 5DROA 3PS3A 4IS9A 2O3ZA 4U3BA 2VESA 4MQYA 5DRRA 2JT2A 4LCFA 3UHMA 4OKGA 3PS1A 1YHCA 4MDTA 4OZEA 4LCHA 4FW5A 2GO4A 3P3GA 3P3CA 5DRPA 3P3EA 3U1YA 3P76A 2IERA 1XXEA 4FW3A 4FW6A 1P42A 4LCGA 2GO3A 3PS2A
chains in the Genus database with same CATH superfamily
4FW4A 2UUBE 1OYPA 1RR9A 2Z5EA 1E3PA 4J3DA 3GMEA 2A2CA 2ZBKB 4MQYA 2UXDI 1B63A 4FWGA 4JI0E 4DR6I 4OX9I 1Y6ZA 2NN6A 3J7AG 4LPFA 2C37B 3U1YA 4AM3A 4YY3I 4LF7I 3M6AA 3PYGA 1VISA 1E3HA 4OO1D 4DR5E 4LF5I 2IESA 4LF9I 4OO1B 4RPFA 2BA0G 4JI6I 1FWLA 2UXCE 1KIJA 4JI4I 1PIEA 3J7AM 3PYEA 1I94E 4OO1E 5K36C 4PRXA 4YY3E 4B3TI 2NN6F 5GMDA 4LF8E 4UT4A 1IBLI 2BM1A 4LFBE 4GKJE 1PKPA 1Z0EA 4LF9E 4MU1A 4DV6I 2VQEE 3J80C 4NXME 4DR2E 4GKKE 4FW9A 3J81C 2AJ4A 4P52A 1D6TA 4B3TE 1IBKI 5K36A 3J80Q 3GCMA 2X36A 1QZRA 2BV3A 2WW4A 5C0XD 5BR8I 4LF4E 3J81Q 3D4JA 4MDTA 4X66I 4I3HA 3ZM7A 4FWDA 2E5LE 2GO4A 4IZKA 5DRPA 1XXEA 4JV5E 4ZVIA 4HACA 2BA1D 1DARA 2C38A 2WP8A 2JEAA 1EI1A 5JEAA 4USKA 5DNLA 4DV5I 3PYFA 1WUUA 3V5RA 4JI5I 2J7KA 2A2DA 1N32I 2JE6A 2CVEA 4Z7YA 2Z5BB 1Z5AA 2PNMA 4AIMA 4AQYE 1N34E 4X62I 1XNQE 3M7NG 4MYUA 1ZXMA 1HNWI 1J5EE 1R6MA 1HNZI 1KKHA 4PU9A 2HFUA 4P7AA 3V2UC 4DV1I 2Z5CB 1H74A 3T1HI 4KHPE 4NBQA 1Z0VA 3K1JA 4MU4A 4DUYE 1EA6A 3QT5A 3LTOA 2O1UA 1N32E 1N0VC 1Y4SA 2V2QA 1H72C 4X64E 4DR1I 4WUDA 4DUZE 4QNJA 5FLXC 4YHHI 4IZJD 4U3BA 4Z7CA 4LFAE 1UDNA 3L7ZB 1HNZE 4BA1A 2UUBI 5FLXQ 1N33E 4K0KE 1S4EA 4UTGA 4JI1E 2HHHE 3P3EA 3B82A 2R42A 3CDIA 2V2VA 4FWHA 4DV7E 2UU9E 2HFSA 1HNXE 4JI0I 2NN6C 4BA2B 2O1WA 4LF6E 2BR2A 3H4LA 1UDOA 2PO2B 3NZKA 4DV3E 2UUCE 4B3ME 1XHKA 2X7IA 3HJCA 5DROA 3KRNA 4N3OA 2O3ZA 4DPUA 5ELWA 4DR5I 2ZM6E 1FJGE 2UXCI 3LPSA 1HR0E 2F4VE 1I94I 3PRYA 4FW6A 4LF8I 5EL9A 4LFBI 5EKWA 4JG4A 2NPFA 4GKJI 4JI8I 4OO1F 3ZKDA 2VQFE 5LMNE 4JI2E 4DU7A 1OYSA 2GQ0A 3Q6NA 2VQEI 4B3RE 4NXMI 3CDJA 4DR2I 4GKKI 4IFDD 1R6LA 2VESA 1N36E 1RHYA 5FWKA 1Y60A 1Z0BA 2F1DA 3B78A 4DPTA 4LFCE 4JI8E 4LF4I 3P76A 4JI7E 4DV4E 2E5LI 1VI7A 2AE8A 2VF3A 3PYDA 4JV5I 4JYAE 4DPXA 2UXBE 2NN6D 2CZ9A 1A6FA 5DRRA 1ZM2A 2HKJA 5JEAC 2PO0B 4OZEA 5C0XB 3WU6A 1Z59A 2Z5BA 3P3GA 1MG7A 3Q1QA 5C0XE 4AQYI 1N34I 4NXNI 4HXZA 1FKAE 1XNQI 1FNMA 4DR3E 1YH8A 2Z5CA 4FW7A 4MU0A 4MU3A 2C39B 1J5EI 1UEKA 1Z5BA 1KVKA 4ISAA 4KHPI 4DUYI 5DNXA 4DR7E 1FI4A 1Z0TA 1ZM3A 3GONA 4DPYA 4X64I 4DUZI 3ZKBA 4NXNE 4FW5A 2OI2A 3L7ZA 4LFAI 1S16A 5K36D 1NHIA 1P42A 1N33I 2JEBB 4K0KI 4JI1I 2HHHI 3QT6A 4DV0E 5GMEA 4B3SE 4BA2A 1Z0GA 5LL6R 4DV7I 2UU9I 1HNXI 1H73A 1N0UA 3UHMA 4LF6I 1XMQE 4IZJB 4OO1C 5IWAE 4DV3I 2UUCI 4DPWA 4GQUA 4B3MI 3P3CA 2ZM6I 2BM0A 5JEAD 3JAMC 1FJGI 2WP8B 4DXLA 3DD6A 3M85G 4LOMA 2PNZB 2C37A 2CG9A 1XNRE 4DV2I 1HR0I 2F4VI 4URLA 4M1KA 3JAMQ 2JE6B 4MYTA 5A2QC 1Y5YA 4JI3I 4OO1A 1NHJA 1Z0CA 2VQFI 5A2QQ 3WU4A 5LMNI 1MU5A 4JI2I 4B3RI 1FWKA 1MX0A 4DV2E 1N36I 2UUAE 4PRVA 1XMOE 2O1VA 3ZZTA 2WNRB 1ZM4A 4JI3E 2EFGA 4LFCI 5L3JA 1ZXNA 5IT9C 4WUBA 4DR4E 4HYMA 1IBME 4X65E 4JI7I 1USVA 1USUA 4U3DA 4BA1B 4DV4I 5LMUE 3LNUA 4IS9A 3K17A 2BA0D 5IT9Q 4IFDF 2ZITA 2E1RA 4IFDB 4JYAI 2CGEA 2PO1B 2UXBI 2V2ZA 3T1YI 3GLLA 2PO0A 5C0XA 1NZ0A 4IFDE 4EMDA 2BR2B 3ZZ0A 4XTJA 1KTVA 2UXDE 1UDSA 5DRQA 2O1TA 4DR6E 4OX9E 2C39A 3T1YE 1Z5CA 1ELOA 4DR3I 4HY1A 2GS8A 4LF7E 3PS1A 1YHCA 2NN6B 3OTOI 5C0XF 1PVGA 4LF5E 1U2RA 2IERA 4JI6E 3B8HA 4DR7I 2NN6E 4FW3A 4WUCA 4JI4E 2XEXA 1H7UA 4LCGA 3Q6MA 4DU8A 2JEBA 2V34A 1IBLE 4R1FA 3OTOE 1H7SA 1K47A 2IOPA 3CWVA 4LCFA 2DEJA 4DV0I 4DV6E 4B3SI 4LCHA 1NHHA 1ZM9A 2BA1G 2DEIA 4IZJA 1Y4UA 1IBKE 3B4TA 1XMQI 3M7ND 2V8PA 4ED4A 5K36F 4KQVA 3PS2A 5IWAI 5BR8E 5K36B 3K85A 4USMA 4X66E 2PNZA 5K36E 1BKNA 1XNRI 4AIDA 2IOQA 3F0NA 4QNKA 2HK3A 2PO2A 3H1CA 4OKGA 4IZKB 1OYRA 4HACB 2HK2A 2PNLA 1OJ4A 3WU5A 2C38B 1HK7A 4DV5E 2GO3A 2LJPA 2JEAB 5JEAF 3P06A 4IFDC 4JI5E 5JEAB 4FN5A 2J65A 2WNRA 3M85D 2UUAI 1UDQA 4X62E 2Q2EB 1XMOI 3QT8A 3PS3A 5JEAE 1HNWE 2JT2A 3QT7A 4DV1E 3T1HE 2R3VA 4DR4I 1IBMI 4X65I 3WU3A 3HULA 1Z0WA 3HKMA 5LMUI 4IFDA 2HKEA 1RREA 4DR1E 2PO1A 1B62A 4YHHE 3ZZUA 5C0XC 3U1KA
chains in the Genus database with same CATH topology
2IESA 1YH8A 2J65A 4FW4A 4FW7A 5DRQA 3NZKA 4ISAA 4J3DA 4U3DA 5DROA 3PS3A 4IS9A 2O3ZA 4U3BA 2VESA 4MQYA 5DRRA 2JT2A 4LCFA 3UHMA 4OKGA 3PS1A 1YHCA 4MDTA 4OZEA 4LCHA 4FW5A 2GO4A 3P3GA 3P3CA 5DRPA 3P3EA 3U1YA 3P76A 2IERA 1XXEA 4FW3A 4FW6A 1P42A 4LCGA 2GO3A 3PS2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IES A;  1YH8 A;  2J65 A;  4FW4 A;  4FW7 A;  5DRQ A;  3NZK A;  4ISA A;  4J3D A;  4U3D A;  5DRO A;  3PS3 A;  4IS9 A;  2O3Z A;  4U3B A;  2VES A;  4MQY A;  5DRR A;  2JT2 A;  4LCF A;  3UHM A;  4OKG A;  3PS1 A;  1YHC A;  4MDT A;  4OZE A;  4LCH A;  4FW5 A;  2GO4 A;  3P3G A;  3P3C A;  5DRP A;  3P3E A;  3U1Y A;  3P76 A;  2IER A;  1XXE A;  4FW3 A;  4FW6 A;  1P42 A;  4LCG A;  2GO3 A;  3PS2 A; 
#chains in the Genus database with same CATH topology
 4FW4 A;  2UUB E;  1OYP A;  1RR9 A;  2Z5E A;  1E3P A;  4J3D A;  3GME A;  2A2C A;  2ZBK B;  4MQY A;  2UXD I;  1B63 A;  4FWG A;  4JI0 E;  4DR6 I;  4OX9 I;  1Y6Z A;  2NN6 A;  3J7A G;  4LPF A;  2C37 B;  3U1Y A;  4AM3 A;  4YY3 I;  4LF7 I;  3M6A A;  3PYG A;  1VIS A;  1E3H A;  4OO1 D;  4DR5 E;  4LF5 I;  2IES A;  4LF9 I;  4OO1 B;  4RPF A;  2BA0 G;  4JI6 I;  1FWL A;  2UXC E;  1KIJ A;  4JI4 I;  1PIE A;  3J7A M;  3PYE A;  1I94 E;  4OO1 E;  5K36 C;  4PRX A;  4YY3 E;  4B3T I;  2NN6 F;  5GMD A;  4LF8 E;  4UT4 A;  1IBL I;  2BM1 A;  4LFB E;  4GKJ E;  1PKP A;  1Z0E A;  4LF9 E;  4MU1 A;  4DV6 I;  2VQE E;  3J80 C;  4NXM E;  4DR2 E;  4GKK E;  4FW9 A;  3J81 C;  2AJ4 A;  4P52 A;  1D6T A;  4B3T E;  1IBK I;  5K36 A;  3J80 Q;  3GCM A;  2X36 A;  1QZR A;  2BV3 A;  2WW4 A;  5C0X D;  5BR8 I;  4LF4 E;  3J81 Q;  3D4J A;  4MDT A;  4X66 I;  4I3H A;  3ZM7 A;  4FWD A;  2E5L E;  2GO4 A;  4IZK A;  5DRP A;  1XXE A;  4JV5 E;  4ZVI A;  4HAC A;  2BA1 D;  1DAR A;  2C38 A;  2WP8 A;  2JEA A;  1EI1 A;  5JEA A;  4USK A;  5DNL A;  4DV5 I;  3PYF A;  1WUU A;  3V5R A;  4JI5 I;  2J7K A;  2A2D A;  1N32 I;  2JE6 A;  2CVE A;  4Z7Y A;  2Z5B B;  1Z5A A;  2PNM A;  4AIM A;  4AQY E;  1N34 E;  4X62 I;  1XNQ E;  3M7N G;  4MYU A;  1ZXM A;  1HNW I;  1J5E E;  1R6M A;  1HNZ I;  1KKH A;  4PU9 A;  2HFU A;  4P7A A;  3V2U C;  4DV1 I;  2Z5C B;  1H74 A;  3T1H I;  4KHP E;  4NBQ A;  1Z0V A;  3K1J A;  4MU4 A;  4DUY E;  1EA6 A;  3QT5 A;  3LTO A;  2O1U A;  1N32 E;  1N0V C;  1Y4S A;  2V2Q A;  1H72 C;  4X64 E;  4DR1 I;  4WUD A;  4DUZ E;  4QNJ A;  5FLX C;  4YHH I;  4IZJ D;  4U3B A;  4Z7C A;  4LFA E;  1UDN A;  3L7Z B;  1HNZ E;  4BA1 A;  2UUB I;  5FLX Q;  1N33 E;  4K0K E;  1S4E A;  4UTG A;  4JI1 E;  2HHH E;  3P3E A;  3B82 A;  2R42 A;  3CDI A;  2V2V A;  4FWH A;  4DV7 E;  2UU9 E;  2HFS A;  1HNX E;  4JI0 I;  2NN6 C;  4BA2 B;  2O1W A;  4LF6 E;  2BR2 A;  3H4L A;  1UDO A;  2PO2 B;  3NZK A;  4DV3 E;  2UUC E;  4B3M E;  1XHK A;  2X7I A;  3HJC A;  5DRO A;  3KRN A;  4N3O A;  2O3Z A;  4DPU A;  5ELW A;  4DR5 I;  2ZM6 E;  1FJG E;  2UXC I;  3LPS A;  1HR0 E;  2F4V E;  1I94 I;  3PRY A;  4FW6 A;  4LF8 I;  5EL9 A;  4LFB I;  5EKW A;  4JG4 A;  2NPF A;  4GKJ I;  4JI8 I;  4OO1 F;  3ZKD A;  2VQF E;  5LMN E;  4JI2 E;  4DU7 A;  1OYS A;  2GQ0 A;  3Q6N A;  2VQE I;  4B3R E;  4NXM I;  3CDJ A;  4DR2 I;  4GKK I;  4IFD D;  1R6L A;  2VES A;  1N36 E;  1RHY A;  5FWK A;  1Y60 A;  1Z0B A;  2F1D A;  3B78 A;  4DPT A;  4LFC E;  4JI8 E;  4LF4 I;  3P76 A;  4JI7 E;  4DV4 E;  2E5L I;  1VI7 A;  2AE8 A;  2VF3 A;  3PYD A;  4JV5 I;  4JYA E;  4DPX A;  2UXB E;  2NN6 D;  2CZ9 A;  1A6F A;  5DRR A;  1ZM2 A;  2HKJ A;  5JEA C;  2PO0 B;  4OZE A;  5C0X B;  3WU6 A;  1Z59 A;  2Z5B A;  3P3G A;  1MG7 A;  3Q1Q A;  5C0X E;  4AQY I;  1N34 I;  4NXN I;  4HXZ A;  1FKA E;  1XNQ I;  1FNM A;  4DR3 E;  1YH8 A;  2Z5C A;  4FW7 A;  4MU0 A;  4MU3 A;  2C39 B;  1J5E I;  1UEK A;  1Z5B A;  1KVK A;  4ISA A;  4KHP I;  4DUY I;  5DNX A;  4DR7 E;  1FI4 A;  1Z0T A;  1ZM3 A;  3GON A;  4DPY A;  4X64 I;  4DUZ I;  3ZKB A;  4NXN E;  4FW5 A;  2OI2 A;  3L7Z A;  4LFA I;  1S16 A;  5K36 D;  1NHI A;  1P42 A;  1N33 I;  2JEB B;  4K0K I;  4JI1 I;  2HHH I;  3QT6 A;  4DV0 E;  5GME A;  4B3S E;  4BA2 A;  1Z0G A;  5LL6 R;  4DV7 I;  2UU9 I;  1HNX I;  1H73 A;  1N0U A;  3UHM A;  4LF6 I;  1XMQ E;  4IZJ B;  4OO1 C;  5IWA E;  4DV3 I;  2UUC I;  4DPW A;  4GQU A;  4B3M I;  3P3C A;  2ZM6 I;  2BM0 A;  5JEA D;  3JAM C;  1FJG I;  2WP8 B;  4DXL A;  3DD6 A;  3M85 G;  4LOM A;  2PNZ B;  2C37 A;  2CG9 A;  1XNR E;  4DV2 I;  1HR0 I;  2F4V I;  4URL A;  4M1K A;  3JAM Q;  2JE6 B;  4MYT A;  5A2Q C;  1Y5Y A;  4JI3 I;  4OO1 A;  1NHJ A;  1Z0C A;  2VQF I;  5A2Q Q;  3WU4 A;  5LMN I;  1MU5 A;  4JI2 I;  4B3R I;  1FWK A;  1MX0 A;  4DV2 E;  1N36 I;  2UUA E;  4PRV A;  1XMO E;  2O1V A;  3ZZT A;  2WNR B;  1ZM4 A;  4JI3 E;  2EFG A;  4LFC I;  5L3J A;  1ZXN A;  5IT9 C;  4WUB A;  4DR4 E;  4HYM A;  1IBM E;  4X65 E;  4JI7 I;  1USV A;  1USU A;  4U3D A;  4BA1 B;  4DV4 I;  5LMU E;  3LNU A;  4IS9 A;  3K17 A;  2BA0 D;  5IT9 Q;  4IFD F;  2ZIT A;  2E1R A;  4IFD B;  4JYA I;  2CGE A;  2PO1 B;  2UXB I;  2V2Z A;  3T1Y I;  3GLL A;  2PO0 A;  5C0X A;  1NZ0 A;  4IFD E;  4EMD A;  2BR2 B;  3ZZ0 A;  4XTJ A;  1KTV A;  2UXD E;  1UDS A;  5DRQ A;  2O1T A;  4DR6 E;  4OX9 E;  2C39 A;  3T1Y E;  1Z5C A;  1ELO A;  4DR3 I;  4HY1 A;  2GS8 A;  4LF7 E;  3PS1 A;  1YHC A;  2NN6 B;  3OTO I;  5C0X F;  1PVG A;  4LF5 E;  1U2R A;  2IER A;  4JI6 E;  3B8H A;  4DR7 I;  2NN6 E;  4FW3 A;  4WUC A;  4JI4 E;  2XEX A;  1H7U A;  4LCG A;  3Q6M A;  4DU8 A;  2JEB A;  2V34 A;  1IBL E;  4R1F A;  3OTO E;  1H7S A;  1K47 A;  2IOP A;  3CWV A;  4LCF A;  2DEJ A;  4DV0 I;  4DV6 E;  4B3S I;  4LCH A;  1NHH A;  1ZM9 A;  2BA1 G;  2DEI A;  4IZJ A;  1Y4U A;  1IBK E;  3B4T A;  1XMQ I;  3M7N D;  2V8P A;  4ED4 A;  5K36 F;  4KQV A;  3PS2 A;  5IWA I;  5BR8 E;  5K36 B;  3K85 A;  4USM A;  4X66 E;  2PNZ A;  5K36 E;  1BKN A;  1XNR I;  4AID A;  2IOQ A;  3F0N A;  4QNK A;  2HK3 A;  2PO2 A;  3H1C A;  4OKG A;  4IZK B;  1OYR A;  4HAC B;  2HK2 A;  2PNL A;  1OJ4 A;  3WU5 A;  2C38 B;  1HK7 A;  4DV5 E;  2GO3 A;  2LJP A;  2JEA B;  5JEA F;  3P06 A;  4IFD C;  4JI5 E;  5JEA B;  4FN5 A;  2J65 A;  2WNR A;  3M85 D;  2UUA I;  1UDQ A;  4X62 E;  2Q2E B;  1XMO I;  3QT8 A;  3PS3 A;  5JEA E;  1HNW E;  2JT2 A;  3QT7 A;  4DV1 E;  3T1H E;  2R3V A;  4DR4 I;  1IBM I;  4X65 I;  3WU3 A;  3HUL A;  1Z0W A;  3HKM A;  5LMU I;  4IFD A;  2HKE A;  1RRE A;  4DR1 E;  2PO1 A;  1B62 A;  4YHH E;  3ZZU A;  5C0X C;  3U1K A; 
#chains in the Genus database with same CATH homology
 2IES A;  1YH8 A;  2J65 A;  4FW4 A;  4FW7 A;  5DRQ A;  3NZK A;  4ISA A;  4J3D A;  4U3D A;  5DRO A;  3PS3 A;  4IS9 A;  2O3Z A;  4U3B A;  2VES A;  4MQY A;  5DRR A;  2JT2 A;  4LCF A;  3UHM A;  4OKG A;  3PS1 A;  1YHC A;  4MDT A;  4OZE A;  4LCH A;  4FW5 A;  2GO4 A;  3P3G A;  3P3C A;  5DRP A;  3P3E A;  3U1Y A;  3P76 A;  2IER A;  1XXE A;  4FW3 A;  4FW6 A;  1P42 A;  4LCG A;  2GO3 A;  3PS2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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