3P76A

X-ray crystal structure of aquifex aeolicus lpxc complexed sch1379777
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Design and synthesis of potent Gram-negative specific LpxC inhibitors.
pubmed doi rcsb
total genus 91
structure length 267
sequence length 267
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2010-10-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3p76A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3p76A02
1YHCA 2GO4A 2O3ZA 4IS9A 4MDTA 4U3DA 2JT2A 3NZKA 2GO3A 5DRRA 4FW3A 4U3BA 4LCHA 3P3GA 4LCFA 4OKGA 3PS2A 3U1YA 2VESA 5DROA 2IERA 1P42A 2IESA 1YH8A 4MQYA 3PS3A 5DRQA 4FW7A 3PS1A 4LCGA 3UHMA 4FW4A 4ISAA 5DRPA 1XXEA 3P3EA 4OZEA 4FW6A 3P3CA 3P76A 4J3DA 2J65A 4FW5A
chains in the Genus database with same CATH superfamily
1EA6A 1J5EI 2O1WA 1HNWI 1XMOE 3T1YE 2GS8A 4LCHA 5DNXA 1Z0WA 5EL9A 4IFDA 4LF4E 1IBLE 2UXBI 5DRQA 4DPXA 2NN6E 2GQ0A 5DRPA 4FWGA 2R42A 1ZXNA 4ZVIA 2UXCI 4JI3E 2V34A 3P3CA 2UUCI 4JI5I 2C38B 5JEAB 2WNRB 4OO1E 3M85D 1Y6ZA 4DU7A 4DR4I 1N34E 3J80Q 4USKA 5K36D 2IOPA 1E3HA 5EKWA 2PO0B 3PS2A 1XMOI 3J7AM 5IWAI 1XHKA 1MX0A 4LFCI 5LMUI 3GONA 1P42A 4EMDA 5A2QQ 1BKNA 4K0KE 1Z0CA 1WUUA 4HXZA 4URLA 3B82A 4DV6E 1DARA 3HJCA 4KHPE 4OO1C 2BV3A 1OJ4A 2C38A 2PNZB 5JEAA 2WNRA 3HULA 4DV1E 4B3RE 4JI3I 4U3DA 2PNMA 3J80C 2PO0A 1PIEA 3P3GA 1OYPA 1N34I 2WP8A 5ELWA 2Z5EA 5A2QC 4HY1A 5C0XE 4FW7A 4BA1B 2UXDE 1N0UA 4LPFA 2PNZA 5GMEA 2BA1G 1Y4UA 4IZKB 5IT9C 2O1UA 4JI6E 1IBKI 3PYDA 4DR5I 4X65E 1KTVA 3H4LA 4JI8I 2ZM6E 4DV1I 5DRRA 3ZZTA 4Z7CA 4B3RI 1B63A 5C0XC 2J7KA 2PO1A 1PVGA 1ZM2A 4GKKE 2ZBKB 4LF6E 4Z7YA 4BA1A 3CDIA 4GQUA 4DU8A 4MYTA 2UUBE 1FJGE 3GCMA 4DR3E 4IZKA 4DPUA 2XEXA 1K47A 3P06A 4OO1B 1USUA 2UXDI 4JI4I 1N32E 4DV0I 3CWVA 2GO3A 1UDNA 1Z5AA 2HHHE 2X7IA 4X62E 1UEKA 3GMEA 4DV2I 4IFDF 5BR8I 3Q1QA 2IERA 5JEAD 1RR9A 1YH8A 4R1FA 4DPWA 1H72C 2EFGA 2Z5CB 1KKHA 4LF8I 4DV3I 4B3SE 3H1CA 4NXNE 4OO1A 4LF6I 4JI1I 4AIMA 1ZM9A 4LF5I 2HK3A 1HNZE 4B3TE 4BA2B 1XNQE 1Z0VA 1Z5BA 4FN5A 1FJGI 1ZM4A 4B3ME 1QZRA 2AE8A 4HYMA 3V2UC 4MU4A 2A2DA 2BA1D 1S16A 1NHHA 3F0NA 2V8PA 1N32I 4PU9A 2VESA 3OTOE 4LFBI 1Z0GA 4GKJE 4P52A 4X64I 2Z5CA 1Y4SA 3PS3A 4JI7E 1I94E 3K17A 4PRVA 3UHMA 1B62A 1XMQE 4DV7E 4BA2A 5K36E 4B3SI 2VF3A 4NXNI 2V2VA 4MU0A 4LF9I 4LFAE 4JG4A 4FW5A 5JEAF 4DR7E 1Z59A 4JYAI 2UUAE 4DV4E 1USVA 2O3ZA 3QT5A 1HNZI 5LL6R 2AJ4A 4JI2E 2BM1A 3T1YI 2NN6C 4LF7E 1FWKA 2WP8B 3J7AG 5K36C 1XNRE 4LF4I 3B78A 1KVKA 1UDOA 4ISAA 1HR0E 1IBLI 4AQYE 2PO2B 3P3EA 4HACB 3PYFA 3K1JA 1IBME 2CG9A 3CDJA 4KQVA 3ZKDA 1XMQI 2VQEE 4AIDA 1UDQA 3M7ND 2O1TA 3DD6A 3WU4A 4X66E 4DV5E 2VQFE 4YHHE 2PO1B 2E5LE 4YY3E 5LMNE 2PO2A 4HACA 3WU6A 4LF7I 1A6FA 3LTOA 1HNXE 5L3JA 4K0KI 1VISA 4DUZE 2Z5BB 1HR0I 4IFDD 1R6LA 4DV6I 3T1HE 4KHPI 2GO4A 4IS9A 1IBMI 3NZKA 3ZZUA 2BA0G 2HFUA 2VQEI 4JV5E 5DNLA 2NN6F 4OX9E 2NN6B 4FWDA 3ZZ0A 4P7AA 2DEIA 4WUBA 5K36B 4FWHA 1N36E 1KIJA 2Z5BA 4OO1F 2JEAA 3QT8A 1NZ0A 2X36A 1H73A 1HNXI 1MU5A 2JT2A 3Q6NA 4DUYE 2C37B 4FW3A 4JI6I 1N33E 2F4VE 4X65I 2HFSA 2ZITA 2HKEA 1NHJA 2NN6A 2ZM6I 2DEJA 3PYEA 5K36A 4UTGA 4NBQA 4GKKI 3M7NG 2CVEA 1E3PA 2CZ9A 2NPFA 1FWLA 2J65A 2UUBI 4LOMA 1N36I 4DR3I 2C37A 1FKAE 4NXME 4MDTA 2V2QA 4DR1E 4U3BA 2BR2A 4LCFA 4N3OA 5C0XF 3L7ZB 5C0XB 1N33I 2UXCE 2BA0D 4DR6E 3PYGA 2HHHI 4X62I 2O1VA 5FWKA 4DR4E 3HKMA 1Y5YA 4WUCA 4JI0E 3J81Q 5IWAE 4LFCE 5LMUE 4IZJB 4B3TI 1XNQI 3L7ZA 1RHYA 5C0XA 2IOQA 4MU3A 4OKGA 4B3MI 4NXMI 4RPFA 2JEBB 4DR1I 3WU3A 3OTOI 1U2RA 4GKJI 5FLXQ 1VI7A 1H74A 2JE6A 4DR6I 4FW9A 4JI7I 4MYUA 1I94I 1N0VC 3J81C 2NN6D 4I3HA 1H7UA 4DV7I 4IZJA 4ED4A 4JI0I 4LFAI 4DR7I 3ZKBA 3QT7A 2JEBA 4QNJA 2UUAI 4DV4I 3QT6A 4OO1D 1Z0EA 2UU9E 3GLLA 3U1KA 4JI2I 4DXLA 3PS1A 4IFDE 1IBKE 4PRXA 4USMA 5FLXC 4DR5E 1Z0BA 5IT9Q 4JI8E 4J3DA 1XNRI 2JEAB 3JAMQ 4AQYI 2WW4A 3V5RA 5GMDA 3Q6MA 4IFDC 3B8HA 3LNUA 3B4TA 1Z5CA 3D4JA 2F1DA 4MQYA 1EI1A 4X66I 4DV5I 4UT4A 4JI4E 2HKJA 1S4EA 2A2CA 5K36F 2E1RA 2UU9I 4DV0E 1NHIA 3ZM7A 4DPTA 2VQFI 4YHHI 2E5LI 1ZXMA 3P76A 4YY3I 5C0XD 4XTJA 2LJPA 3LPSA 5LMNI 1YHCA 4DV2E 3JAMC 5BR8E 2V2ZA 5JEAE 2C39B 4DUZI 3T1HI 2Q2EB 3M6AA 4LF8E 3U1YA 4DV3E 1FI4A 2BR2B 1OYSA 4JI1E 2IESA 1Z0TA 4LF5E 4JV5I 4IZJD 4LCGA 4DR2E 3M85G 2OI2A 3KRNA 4OX9I 1HK7A 4AM3A 4M1KA 1J5EE 4WUDA 1OYRA 3WU5A 1HNWE 2CGEA 1PKPA 5JEAC 1ZM3A 2PNLA 2C39A 2BM0A 4LFBE 1D6TA 1Y60A 4X64E 1FNMA 2UXBE 3K85A 1ELOA 3PRYA 5DROA 4DUYI 4QNKA 4IFDB 4MU1A 1H7SA 2F4VI 2HK2A 4LF9E 1RREA 2UUCE 4FW4A 4JI5E 4JYAE 1UDSA 2R3VA 1XXEA 4OZEA 4FW6A 4DR2I 4DPYA 1MG7A 1R6MA 2JE6B
chains in the Genus database with same CATH topology
1YHCA 2GO4A 2O3ZA 4IS9A 4MDTA 4U3DA 2JT2A 3NZKA 2GO3A 5DRRA 4FW3A 4U3BA 4LCHA 3P3GA 4LCFA 4OKGA 3PS2A 3U1YA 2VESA 5DROA 2IERA 1P42A 2IESA 1YH8A 4MQYA 3PS3A 5DRQA 4FW7A 3PS1A 4LCGA 3UHMA 4FW4A 4ISAA 5DRPA 1XXEA 3P3EA 4OZEA 4FW6A 3P3CA 3P76A 4J3DA 2J65A 4FW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YHC A;  2GO4 A;  2O3Z A;  4IS9 A;  4MDT A;  4U3D A;  2JT2 A;  3NZK A;  2GO3 A;  5DRR A;  4FW3 A;  4U3B A;  4LCH A;  3P3G A;  4LCF A;  4OKG A;  3PS2 A;  3U1Y A;  2VES A;  5DRO A;  2IER A;  1P42 A;  2IES A;  1YH8 A;  4MQY A;  3PS3 A;  5DRQ A;  4FW7 A;  3PS1 A;  4LCG A;  3UHM A;  4FW4 A;  4ISA A;  5DRP A;  1XXE A;  3P3E A;  4OZE A;  4FW6 A;  3P3C A;  3P76 A;  4J3D A;  2J65 A;  4FW5 A; 
#chains in the Genus database with same CATH topology
 1EA6 A;  1J5E I;  2O1W A;  1HNW I;  1XMO E;  3T1Y E;  2GS8 A;  4LCH A;  5DNX A;  1Z0W A;  5EL9 A;  4IFD A;  4LF4 E;  1IBL E;  2UXB I;  5DRQ A;  4DPX A;  2NN6 E;  2GQ0 A;  5DRP A;  4FWG A;  2R42 A;  1ZXN A;  4ZVI A;  2UXC I;  4JI3 E;  2V34 A;  3P3C A;  2UUC I;  4JI5 I;  2C38 B;  5JEA B;  2WNR B;  4OO1 E;  3M85 D;  1Y6Z A;  4DU7 A;  4DR4 I;  1N34 E;  3J80 Q;  4USK A;  5K36 D;  2IOP A;  1E3H A;  5EKW A;  2PO0 B;  3PS2 A;  1XMO I;  3J7A M;  5IWA I;  1XHK A;  1MX0 A;  4LFC I;  5LMU I;  3GON A;  1P42 A;  4EMD A;  5A2Q Q;  1BKN A;  4K0K E;  1Z0C A;  1WUU A;  4HXZ A;  4URL A;  3B82 A;  4DV6 E;  1DAR A;  3HJC A;  4KHP E;  4OO1 C;  2BV3 A;  1OJ4 A;  2C38 A;  2PNZ B;  5JEA A;  2WNR A;  3HUL A;  4DV1 E;  4B3R E;  4JI3 I;  4U3D A;  2PNM A;  3J80 C;  2PO0 A;  1PIE A;  3P3G A;  1OYP A;  1N34 I;  2WP8 A;  5ELW A;  2Z5E A;  5A2Q C;  4HY1 A;  5C0X E;  4FW7 A;  4BA1 B;  2UXD E;  1N0U A;  4LPF A;  2PNZ A;  5GME A;  2BA1 G;  1Y4U A;  4IZK B;  5IT9 C;  2O1U A;  4JI6 E;  1IBK I;  3PYD A;  4DR5 I;  4X65 E;  1KTV A;  3H4L A;  4JI8 I;  2ZM6 E;  4DV1 I;  5DRR A;  3ZZT A;  4Z7C A;  4B3R I;  1B63 A;  5C0X C;  2J7K A;  2PO1 A;  1PVG A;  1ZM2 A;  4GKK E;  2ZBK B;  4LF6 E;  4Z7Y A;  4BA1 A;  3CDI A;  4GQU A;  4DU8 A;  4MYT A;  2UUB E;  1FJG E;  3GCM A;  4DR3 E;  4IZK A;  4DPU A;  2XEX A;  1K47 A;  3P06 A;  4OO1 B;  1USU A;  2UXD I;  4JI4 I;  1N32 E;  4DV0 I;  3CWV A;  2GO3 A;  1UDN A;  1Z5A A;  2HHH E;  2X7I A;  4X62 E;  1UEK A;  3GME A;  4DV2 I;  4IFD F;  5BR8 I;  3Q1Q A;  2IER A;  5JEA D;  1RR9 A;  1YH8 A;  4R1F A;  4DPW A;  1H72 C;  2EFG A;  2Z5C B;  1KKH A;  4LF8 I;  4DV3 I;  4B3S E;  3H1C A;  4NXN E;  4OO1 A;  4LF6 I;  4JI1 I;  4AIM A;  1ZM9 A;  4LF5 I;  2HK3 A;  1HNZ E;  4B3T E;  4BA2 B;  1XNQ E;  1Z0V A;  1Z5B A;  4FN5 A;  1FJG I;  1ZM4 A;  4B3M E;  1QZR A;  2AE8 A;  4HYM A;  3V2U C;  4MU4 A;  2A2D A;  2BA1 D;  1S16 A;  1NHH A;  3F0N A;  2V8P A;  1N32 I;  4PU9 A;  2VES A;  3OTO E;  4LFB I;  1Z0G A;  4GKJ E;  4P52 A;  4X64 I;  2Z5C A;  1Y4S A;  3PS3 A;  4JI7 E;  1I94 E;  3K17 A;  4PRV A;  3UHM A;  1B62 A;  1XMQ E;  4DV7 E;  4BA2 A;  5K36 E;  4B3S I;  2VF3 A;  4NXN I;  2V2V A;  4MU0 A;  4LF9 I;  4LFA E;  4JG4 A;  4FW5 A;  5JEA F;  4DR7 E;  1Z59 A;  4JYA I;  2UUA E;  4DV4 E;  1USV A;  2O3Z A;  3QT5 A;  1HNZ I;  5LL6 R;  2AJ4 A;  4JI2 E;  2BM1 A;  3T1Y I;  2NN6 C;  4LF7 E;  1FWK A;  2WP8 B;  3J7A G;  5K36 C;  1XNR E;  4LF4 I;  3B78 A;  1KVK A;  1UDO A;  4ISA A;  1HR0 E;  1IBL I;  4AQY E;  2PO2 B;  3P3E A;  4HAC B;  3PYF A;  3K1J A;  1IBM E;  2CG9 A;  3CDJ A;  4KQV A;  3ZKD A;  1XMQ I;  2VQE E;  4AID A;  1UDQ A;  3M7N D;  2O1T A;  3DD6 A;  3WU4 A;  4X66 E;  4DV5 E;  2VQF E;  4YHH E;  2PO1 B;  2E5L E;  4YY3 E;  5LMN E;  2PO2 A;  4HAC A;  3WU6 A;  4LF7 I;  1A6F A;  3LTO A;  1HNX E;  5L3J A;  4K0K I;  1VIS A;  4DUZ E;  2Z5B B;  1HR0 I;  4IFD D;  1R6L A;  4DV6 I;  3T1H E;  4KHP I;  2GO4 A;  4IS9 A;  1IBM I;  3NZK A;  3ZZU A;  2BA0 G;  2HFU A;  2VQE I;  4JV5 E;  5DNL A;  2NN6 F;  4OX9 E;  2NN6 B;  4FWD A;  3ZZ0 A;  4P7A A;  2DEI A;  4WUB A;  5K36 B;  4FWH A;  1N36 E;  1KIJ A;  2Z5B A;  4OO1 F;  2JEA A;  3QT8 A;  1NZ0 A;  2X36 A;  1H73 A;  1HNX I;  1MU5 A;  2JT2 A;  3Q6N A;  4DUY E;  2C37 B;  4FW3 A;  4JI6 I;  1N33 E;  2F4V E;  4X65 I;  2HFS A;  2ZIT A;  2HKE A;  1NHJ A;  2NN6 A;  2ZM6 I;  2DEJ A;  3PYE A;  5K36 A;  4UTG A;  4NBQ A;  4GKK I;  3M7N G;  2CVE A;  1E3P A;  2CZ9 A;  2NPF A;  1FWL A;  2J65 A;  2UUB I;  4LOM A;  1N36 I;  4DR3 I;  2C37 A;  1FKA E;  4NXM E;  4MDT A;  2V2Q A;  4DR1 E;  4U3B A;  2BR2 A;  4LCF A;  4N3O A;  5C0X F;  3L7Z B;  5C0X B;  1N33 I;  2UXC E;  2BA0 D;  4DR6 E;  3PYG A;  2HHH I;  4X62 I;  2O1V A;  5FWK A;  4DR4 E;  3HKM A;  1Y5Y A;  4WUC A;  4JI0 E;  3J81 Q;  5IWA E;  4LFC E;  5LMU E;  4IZJ B;  4B3T I;  1XNQ I;  3L7Z A;  1RHY A;  5C0X A;  2IOQ A;  4MU3 A;  4OKG A;  4B3M I;  4NXM I;  4RPF A;  2JEB B;  4DR1 I;  3WU3 A;  3OTO I;  1U2R A;  4GKJ I;  5FLX Q;  1VI7 A;  1H74 A;  2JE6 A;  4DR6 I;  4FW9 A;  4JI7 I;  4MYU A;  1I94 I;  1N0V C;  3J81 C;  2NN6 D;  4I3H A;  1H7U A;  4DV7 I;  4IZJ A;  4ED4 A;  4JI0 I;  4LFA I;  4DR7 I;  3ZKB A;  3QT7 A;  2JEB A;  4QNJ A;  2UUA I;  4DV4 I;  3QT6 A;  4OO1 D;  1Z0E A;  2UU9 E;  3GLL A;  3U1K A;  4JI2 I;  4DXL A;  3PS1 A;  4IFD E;  1IBK E;  4PRX A;  4USM A;  5FLX C;  4DR5 E;  1Z0B A;  5IT9 Q;  4JI8 E;  4J3D A;  1XNR I;  2JEA B;  3JAM Q;  4AQY I;  2WW4 A;  3V5R A;  5GMD A;  3Q6M A;  4IFD C;  3B8H A;  3LNU A;  3B4T A;  1Z5C A;  3D4J A;  2F1D A;  4MQY A;  1EI1 A;  4X66 I;  4DV5 I;  4UT4 A;  4JI4 E;  2HKJ A;  1S4E A;  2A2C A;  5K36 F;  2E1R A;  2UU9 I;  4DV0 E;  1NHI A;  3ZM7 A;  4DPT A;  2VQF I;  4YHH I;  2E5L I;  1ZXM A;  3P76 A;  4YY3 I;  5C0X D;  4XTJ A;  2LJP A;  3LPS A;  5LMN I;  1YHC A;  4DV2 E;  3JAM C;  5BR8 E;  2V2Z A;  5JEA E;  2C39 B;  4DUZ I;  3T1H I;  2Q2E B;  3M6A A;  4LF8 E;  3U1Y A;  4DV3 E;  1FI4 A;  2BR2 B;  1OYS A;  4JI1 E;  2IES A;  1Z0T A;  4LF5 E;  4JV5 I;  4IZJ D;  4LCG A;  4DR2 E;  3M85 G;  2OI2 A;  3KRN A;  4OX9 I;  1HK7 A;  4AM3 A;  4M1K A;  1J5E E;  4WUD A;  1OYR A;  3WU5 A;  1HNW E;  2CGE A;  1PKP A;  5JEA C;  1ZM3 A;  2PNL A;  2C39 A;  2BM0 A;  4LFB E;  1D6T A;  1Y60 A;  4X64 E;  1FNM A;  2UXB E;  3K85 A;  1ELO A;  3PRY A;  5DRO A;  4DUY I;  4QNK A;  4IFD B;  4MU1 A;  1H7S A;  2F4V I;  2HK2 A;  4LF9 E;  1RRE A;  2UUC E;  4FW4 A;  4JI5 E;  4JYA E;  1UDS A;  2R3V A;  1XXE A;  4OZE A;  4FW6 A;  4DR2 I;  4DPY A;  1MG7 A;  1R6M A;  2JE6 B; 
#chains in the Genus database with same CATH homology
 1YHC A;  2GO4 A;  2O3Z A;  4IS9 A;  4MDT A;  4U3D A;  2JT2 A;  3NZK A;  2GO3 A;  5DRR A;  4FW3 A;  4U3B A;  4LCH A;  3P3G A;  4LCF A;  4OKG A;  3PS2 A;  3U1Y A;  2VES A;  5DRO A;  2IER A;  1P42 A;  2IES A;  1YH8 A;  4MQY A;  3PS3 A;  5DRQ A;  4FW7 A;  3PS1 A;  4LCG A;  3UHM A;  4FW4 A;  4ISA A;  5DRP A;  1XXE A;  3P3E A;  4OZE A;  4FW6 A;  3P3C A;  3P76 A;  4J3D A;  2J65 A;  4FW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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