2O3ZA

X-ray crystal structure of lpxc complexed with 3-heptyloxybenzoate
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC.
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 91
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2o3zA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2o3zA02
2VESA 2GO3A 3PS1A 2JT2A 3NZKA 4IS9A 4LCHA 4U3DA 4U3BA 2O3ZA 4FW3A 4ISAA 4MDTA 4LCGA 4OZEA 5DROA 2J65A 1YH8A 2GO4A 1YHCA 2IERA 4FW5A 1P42A 3P3CA 4LCFA 4OKGA 4FW4A 4FW7A 4J3DA 3P76A 3PS3A 4MQYA 3UHMA 5DRPA 3P3EA 5DRRA 1XXEA 3PS2A 3P3GA 3U1YA 4FW6A 5DRQA 2IESA
chains in the Genus database with same CATH superfamily
1OYSA 2UUAE 3PS1A 4JI7E 2Z5CA 4B3SE 1FNMA 4WUCA 1U2RA 2GQ0A 1PIEA 4DR2I 2F4VE 4DV1E 4HXZA 4GKKE 4BA1B 4FW5A 4AIDA 4LF9I 4B3ME 4DR1I 1XNRE 4GKJI 4FWHA 2EFGA 2A2DA 1Y4SA 4DV2E 2VF3A 3T1YE 3WU5A 2VQEI 4LF5I 5DNLA 4Z7YA 3CDJA 1N34E 2JT2A 2JEAB 4U3BA 4JI8E 1H74A 4DPTA 1Z59A 4USKA 1USVA 3CWVA 4IZJB 2UU9I 4OKGA 4DV4E 4DR4I 1HNXE 3L7ZB 4LF6I 4LF7I 5LMUE 1VI7A 4AIMA 4LFBI 5JEAD 1N0UA 4N3OA 2C39A 2JE6A 2NN6B 3B4TA 4FW9A 3J80Q 4MU4A 2V2VA 4X64E 4DV7I 3Q1QA 3T1HE 1J5EI 4JI6E 1IBLI 2HK2A 4NBQA 1USUA 5BR8E 4JI2E 2PNLA 3V5RA 4HY1A 3M7ND 3HJCA 4B3TI 1MU5A 4DR2E 4BA1A 4X62I 1OYPA 1PKPA 4KHPI 3QT8A 4LF9E 3JAMQ 4IFDB 4X65E 4JI3I 2LJPA 1E3HA 4ZVIA 3H4LA 4JI7I 4OX9E 3HKMA 3ZKBA 4B3SI 2NN6E 2AJ4A 3PYEA 3PYGA 5IT9Q 5C0XB 4OO1B 4LF5E 3KRNA 1RR9A 1OYRA 4ISAA 2JEAA 4LCGA 3PYFA 4B3MI 4KQVA 4LPFA 3PYDA 1XNRI 5JEAC 1Z5BA 5C0XF 4IZJA 3T1YI 3DD6A 4GQUA 4DV6I 3L7ZA 4NXNI 4DR6I 4MDTA 1Y60A 2NN6A 4LF8E 4IFDE 1H7SA 4JV5E 5A2QQ 3PRYA 4DU7A 4JI8I 3WU4A 2PO1A 1FWLA 2OI2A 1J5EE 5C0XE 1IBLE 4OO1E 2PNMA 2BM0A 4DV4I 4QNKA 4DUYE 5IWAI 2BR2A 5K36F 1S16A 2V2ZA 3ZZUA 5EL9A 3P3EA 1B63A 4LFCE 4X64I 4IZKB 1XMOI 3T1HI 4JI0E 3K17A 4PRVA 4IFDA 5BR8I 4JI3E 4JYAE 1NHHA 1MX0A 5K36C 3ZKDA 4OO1A 1NHJA 5FLXC 2C38B 2WP8A 2BA1D 3Q6NA 1IBMI 3QT5A 1Z5AA 2O1TA 3J7AG 2ZBKB 4UTGA 4X65I 4DUZI 3D4JA 1K47A 4OX9I 2HKEA 4DR5I 2HHHE 4DR7E 2A2CA 2HKJA 4DV6E 2IESA 3PS3A 2VESA 4DR3E 2GO3A 1XHKA 2AE8A 4MU1A 2X36A 4NXNE 4DR6E 1UDNA 3V2UC 2Z5BB 2V34A 2F1DA 1WUUA 2UUCE 4JI4E 2PO2B 1FWKA 4USMA 4DV3E 4FW4A 2O1WA 4FW7A 3ZZ0A 2CVEA 1A6FA 5FWKA 1N32E 3HULA 5IWAE 4R1FA 4DV0E 4IZJD 2XEXA 4JV5I 1H72C 4LF8I 3Q6MA 4NXME 1PVGA 4BA2B 2UXCE 2IOPA 4IZKA 4JI1E 3QT6A 2O1UA 1XMOE 2NN6D 2C37B 4JI5I 5LMNE 2O1VA 4LF4E 3WU3A 4FW3A 3GONA 4DUYI 5JEAB 3QT7A 2IERA 1XNQE 1KTVA 4DPWA 1ZM9A 4LFCI 1KVKA 3J81Q 2E5LI 4DPYA 4JI0I 1IBME 1H7UA 1QZRA 2CG9A 4ED4A 3WU6A 1XMQI 4JYAI 3U1KA 4DUZE 1ZXNA 5JEAF 5DRQA 4P52A 4YHHE 4IFDD 4DR5E 4UT4A 1EA6A 1ELOA 2JEBB 3CDIA 2UXDE 5GMEA 2GO4A 1ZM4A 3K1JA 1Z0TA 1RREA 2Z5BA 4OO1D 2Q2EB 5JEAE 2PO2A 4YY3I 1Z0EA 1EI1A 3GCMA 2BA0G 2WNRB 2HHHI 4DR7I 4DR3I 3M6AA 4LOMA 1R6MA 1I94E 5K36B 1VISA 2VQFI 1Y4UA 4LCHA 1IBKE 4DV5I 1ZM3A 4DU8A 1HR0I 2UUCI 4JI4I 2O3ZA 4MYUA 4DV3I 3M85G 4FWDA 4JI5E 4FWGA 1P42A 5ELWA 1NHIA 1Y6ZA 1N32I 1Z0VA 3GLLA 4DV0I 3ZZTA 1Z5CA 3P76A 4MQYA 4NXMI 2UXCI 2DEJA 4JI1I 2BA0D 4MU3A 2E5LE 3P3GA 2ZM6I 5LMNI 4LF4I 4B3RE 4Z7CA 3F0NA 1XMQE 4AQYE 1S4EA 5K36E 4PU9A 1XNQI 5C0XA 2E1RA 1Z0WA 4K0KE 1KKHA 1FKAE 4MU0A 1Z0BA 4J3DA 2V8PA 3UHMA 3JAMC 4YY3E 2ZITA 2BV3A 4YHHI 2WNRA 3U1YA 3B82A 5IT9C 3B8HA 4MYTA 3ZM7A 2UXDI 5K36A 5DNXA 1HNZI 2VQFE 3P06A 4DV5E 1N33I 1HR0E 1HNWE 2R42A 1FI4A 1FJGE 1UDOA 2HK3A 2PO0B 1D6TA 4URLA 1I94I 1Z0CA 5DRRA 4DXLA 5EKWA 1R6LA 1IBKI 1YH8A 5A2QC 3M7NG 1HK7A 1B62A 1N36E 1Z0GA 2PNZB 2ZM6E 2UUBI 1DARA 2R3VA 3J7AM 2UXBE 4LCFA 1E3PA 2V2QA 2C38A 1H73A 3OTOE 2GS8A 1ZXMA 4JG4A 2HFUA 5LL6R 4X66E 4B3RI 4AQYI 2PO1B 3LNUA 1OJ4A 1UEKA 3K85A 2BR2B 4HYMA 2NN6F 4K0KI 4OZEA 4P7AA 3B78A 2NPFA 2X7IA 4LFAI 2J7KA 3GMEA 3LPSA 1HNZE 5C0XD 5FLXQ 3P3CA 4RPFA 1N33E 4HACB 4XTJA 2WW4A 4WUDA 4DR1E 4AM3A 2PO0A 2UUAI 1XXEA 4GKJE 2Z5CB 4FW6A 2NN6C 4EMDA 4IS9A 2VQEE 2F4VI 4PRXA 4DV1I 4GKKI 4BA2A 2WP8B 1HNWI 4IFDF 5K36D 2Z5EA 3H1CA 1Y5YA 2C37A 2J65A 5DROA 2PNZA 1FJGI 1YHCA 2DEIA 2UUBE 1UDSA 4DV2I 4QNJA 5JEAA 2UU9E 4OO1F 1ZM2A 1MG7A 4DR4E 5GMDA 3J80C 4LF6E 1N34I 4LF7E 1NZ0A 4DPUA 2BM1A 3PS2A 4LFBE 4IFDC 1N36I 4M1KA 3NZKA 4I3HA 4U3DA 4DV7E 1N0VC 5L3JA 4FN5A 2BA1G 2UXBI 5C0XC 4OO1C 1HNXI 1UDQA 5LMUI 2CGEA 2HFSA 1BKNA 3OTOI 2JEBA 2IOQA 2C39B 2JE6B 3LTOA 3J81C 3M85D 4LFAE 4B3TE 4X66I 5DRPA 1KIJA 4X62E 1RHYA 4HACA 4JI6I 2CZ9A 4KHPE 4DPXA 4WUBA 4JI2I
chains in the Genus database with same CATH topology
2VESA 2GO3A 3PS1A 2JT2A 3NZKA 4IS9A 4LCHA 4U3DA 4U3BA 2O3ZA 4FW3A 4ISAA 4MDTA 4LCGA 4OZEA 5DROA 2J65A 1YH8A 2GO4A 1YHCA 2IERA 4FW5A 1P42A 3P3CA 4LCFA 4OKGA 4FW4A 4FW7A 4J3DA 3P76A 3PS3A 4MQYA 3UHMA 5DRPA 3P3EA 5DRRA 1XXEA 3PS2A 3P3GA 3U1YA 4FW6A 5DRQA 2IESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VES A;  2GO3 A;  3PS1 A;  2JT2 A;  3NZK A;  4IS9 A;  4LCH A;  4U3D A;  4U3B A;  2O3Z A;  4FW3 A;  4ISA A;  4MDT A;  4LCG A;  4OZE A;  5DRO A;  2J65 A;  1YH8 A;  2GO4 A;  1YHC A;  2IER A;  4FW5 A;  1P42 A;  3P3C A;  4LCF A;  4OKG A;  4FW4 A;  4FW7 A;  4J3D A;  3P76 A;  3PS3 A;  4MQY A;  3UHM A;  5DRP A;  3P3E A;  5DRR A;  1XXE A;  3PS2 A;  3P3G A;  3U1Y A;  4FW6 A;  5DRQ A;  2IES A; 
#chains in the Genus database with same CATH topology
 1OYS A;  2UUA E;  3PS1 A;  4JI7 E;  2Z5C A;  4B3S E;  1FNM A;  4WUC A;  1U2R A;  2GQ0 A;  1PIE A;  4DR2 I;  2F4V E;  4DV1 E;  4HXZ A;  4GKK E;  4BA1 B;  4FW5 A;  4AID A;  4LF9 I;  4B3M E;  4DR1 I;  1XNR E;  4GKJ I;  4FWH A;  2EFG A;  2A2D A;  1Y4S A;  4DV2 E;  2VF3 A;  3T1Y E;  3WU5 A;  2VQE I;  4LF5 I;  5DNL A;  4Z7Y A;  3CDJ A;  1N34 E;  2JT2 A;  2JEA B;  4U3B A;  4JI8 E;  1H74 A;  4DPT A;  1Z59 A;  4USK A;  1USV A;  3CWV A;  4IZJ B;  2UU9 I;  4OKG A;  4DV4 E;  4DR4 I;  1HNX E;  3L7Z B;  4LF6 I;  4LF7 I;  5LMU E;  1VI7 A;  4AIM A;  4LFB I;  5JEA D;  1N0U A;  4N3O A;  2C39 A;  2JE6 A;  2NN6 B;  3B4T A;  4FW9 A;  3J80 Q;  4MU4 A;  2V2V A;  4X64 E;  4DV7 I;  3Q1Q A;  3T1H E;  1J5E I;  4JI6 E;  1IBL I;  2HK2 A;  4NBQ A;  1USU A;  5BR8 E;  4JI2 E;  2PNL A;  3V5R A;  4HY1 A;  3M7N D;  3HJC A;  4B3T I;  1MU5 A;  4DR2 E;  4BA1 A;  4X62 I;  1OYP A;  1PKP A;  4KHP I;  3QT8 A;  4LF9 E;  3JAM Q;  4IFD B;  4X65 E;  4JI3 I;  2LJP A;  1E3H A;  4ZVI A;  3H4L A;  4JI7 I;  4OX9 E;  3HKM A;  3ZKB A;  4B3S I;  2NN6 E;  2AJ4 A;  3PYE A;  3PYG A;  5IT9 Q;  5C0X B;  4OO1 B;  4LF5 E;  3KRN A;  1RR9 A;  1OYR A;  4ISA A;  2JEA A;  4LCG A;  3PYF A;  4B3M I;  4KQV A;  4LPF A;  3PYD A;  1XNR I;  5JEA C;  1Z5B A;  5C0X F;  4IZJ A;  3T1Y I;  3DD6 A;  4GQU A;  4DV6 I;  3L7Z A;  4NXN I;  4DR6 I;  4MDT A;  1Y60 A;  2NN6 A;  4LF8 E;  4IFD E;  1H7S A;  4JV5 E;  5A2Q Q;  3PRY A;  4DU7 A;  4JI8 I;  3WU4 A;  2PO1 A;  1FWL A;  2OI2 A;  1J5E E;  5C0X E;  1IBL E;  4OO1 E;  2PNM A;  2BM0 A;  4DV4 I;  4QNK A;  4DUY E;  5IWA I;  2BR2 A;  5K36 F;  1S16 A;  2V2Z A;  3ZZU A;  5EL9 A;  3P3E A;  1B63 A;  4LFC E;  4X64 I;  4IZK B;  1XMO I;  3T1H I;  4JI0 E;  3K17 A;  4PRV A;  4IFD A;  5BR8 I;  4JI3 E;  4JYA E;  1NHH A;  1MX0 A;  5K36 C;  3ZKD A;  4OO1 A;  1NHJ A;  5FLX C;  2C38 B;  2WP8 A;  2BA1 D;  3Q6N A;  1IBM I;  3QT5 A;  1Z5A A;  2O1T A;  3J7A G;  2ZBK B;  4UTG A;  4X65 I;  4DUZ I;  3D4J A;  1K47 A;  4OX9 I;  2HKE A;  4DR5 I;  2HHH E;  4DR7 E;  2A2C A;  2HKJ A;  4DV6 E;  2IES A;  3PS3 A;  2VES A;  4DR3 E;  2GO3 A;  1XHK A;  2AE8 A;  4MU1 A;  2X36 A;  4NXN E;  4DR6 E;  1UDN A;  3V2U C;  2Z5B B;  2V34 A;  2F1D A;  1WUU A;  2UUC E;  4JI4 E;  2PO2 B;  1FWK A;  4USM A;  4DV3 E;  4FW4 A;  2O1W A;  4FW7 A;  3ZZ0 A;  2CVE A;  1A6F A;  5FWK A;  1N32 E;  3HUL A;  5IWA E;  4R1F A;  4DV0 E;  4IZJ D;  2XEX A;  4JV5 I;  1H72 C;  4LF8 I;  3Q6M A;  4NXM E;  1PVG A;  4BA2 B;  2UXC E;  2IOP A;  4IZK A;  4JI1 E;  3QT6 A;  2O1U A;  1XMO E;  2NN6 D;  2C37 B;  4JI5 I;  5LMN E;  2O1V A;  4LF4 E;  3WU3 A;  4FW3 A;  3GON A;  4DUY I;  5JEA B;  3QT7 A;  2IER A;  1XNQ E;  1KTV A;  4DPW A;  1ZM9 A;  4LFC I;  1KVK A;  3J81 Q;  2E5L I;  4DPY A;  4JI0 I;  1IBM E;  1H7U A;  1QZR A;  2CG9 A;  4ED4 A;  3WU6 A;  1XMQ I;  4JYA I;  3U1K A;  4DUZ E;  1ZXN A;  5JEA F;  5DRQ A;  4P52 A;  4YHH E;  4IFD D;  4DR5 E;  4UT4 A;  1EA6 A;  1ELO A;  2JEB B;  3CDI A;  2UXD E;  5GME A;  2GO4 A;  1ZM4 A;  3K1J A;  1Z0T A;  1RRE A;  2Z5B A;  4OO1 D;  2Q2E B;  5JEA E;  2PO2 A;  4YY3 I;  1Z0E A;  1EI1 A;  3GCM A;  2BA0 G;  2WNR B;  2HHH I;  4DR7 I;  4DR3 I;  3M6A A;  4LOM A;  1R6M A;  1I94 E;  5K36 B;  1VIS A;  2VQF I;  1Y4U A;  4LCH A;  1IBK E;  4DV5 I;  1ZM3 A;  4DU8 A;  1HR0 I;  2UUC I;  4JI4 I;  2O3Z A;  4MYU A;  4DV3 I;  3M85 G;  4FWD A;  4JI5 E;  4FWG A;  1P42 A;  5ELW A;  1NHI A;  1Y6Z A;  1N32 I;  1Z0V A;  3GLL A;  4DV0 I;  3ZZT A;  1Z5C A;  3P76 A;  4MQY A;  4NXM I;  2UXC I;  2DEJ A;  4JI1 I;  2BA0 D;  4MU3 A;  2E5L E;  3P3G A;  2ZM6 I;  5LMN I;  4LF4 I;  4B3R E;  4Z7C A;  3F0N A;  1XMQ E;  4AQY E;  1S4E A;  5K36 E;  4PU9 A;  1XNQ I;  5C0X A;  2E1R A;  1Z0W A;  4K0K E;  1KKH A;  1FKA E;  4MU0 A;  1Z0B A;  4J3D A;  2V8P A;  3UHM A;  3JAM C;  4YY3 E;  2ZIT A;  2BV3 A;  4YHH I;  2WNR A;  3U1Y A;  3B82 A;  5IT9 C;  3B8H A;  4MYT A;  3ZM7 A;  2UXD I;  5K36 A;  5DNX A;  1HNZ I;  2VQF E;  3P06 A;  4DV5 E;  1N33 I;  1HR0 E;  1HNW E;  2R42 A;  1FI4 A;  1FJG E;  1UDO A;  2HK3 A;  2PO0 B;  1D6T A;  4URL A;  1I94 I;  1Z0C A;  5DRR A;  4DXL A;  5EKW A;  1R6L A;  1IBK I;  1YH8 A;  5A2Q C;  3M7N G;  1HK7 A;  1B62 A;  1N36 E;  1Z0G A;  2PNZ B;  2ZM6 E;  2UUB I;  1DAR A;  2R3V A;  3J7A M;  2UXB E;  4LCF A;  1E3P A;  2V2Q A;  2C38 A;  1H73 A;  3OTO E;  2GS8 A;  1ZXM A;  4JG4 A;  2HFU A;  5LL6 R;  4X66 E;  4B3R I;  4AQY I;  2PO1 B;  3LNU A;  1OJ4 A;  1UEK A;  3K85 A;  2BR2 B;  4HYM A;  2NN6 F;  4K0K I;  4OZE A;  4P7A A;  3B78 A;  2NPF A;  2X7I A;  4LFA I;  2J7K A;  3GME A;  3LPS A;  1HNZ E;  5C0X D;  5FLX Q;  3P3C A;  4RPF A;  1N33 E;  4HAC B;  4XTJ A;  2WW4 A;  4WUD A;  4DR1 E;  4AM3 A;  2PO0 A;  2UUA I;  1XXE A;  4GKJ E;  2Z5C B;  4FW6 A;  2NN6 C;  4EMD A;  4IS9 A;  2VQE E;  2F4V I;  4PRX A;  4DV1 I;  4GKK I;  4BA2 A;  2WP8 B;  1HNW I;  4IFD F;  5K36 D;  2Z5E A;  3H1C A;  1Y5Y A;  2C37 A;  2J65 A;  5DRO A;  2PNZ A;  1FJG I;  1YHC A;  2DEI A;  2UUB E;  1UDS A;  4DV2 I;  4QNJ A;  5JEA A;  2UU9 E;  4OO1 F;  1ZM2 A;  1MG7 A;  4DR4 E;  5GMD A;  3J80 C;  4LF6 E;  1N34 I;  4LF7 E;  1NZ0 A;  4DPU A;  2BM1 A;  3PS2 A;  4LFB E;  4IFD C;  1N36 I;  4M1K A;  3NZK A;  4I3H A;  4U3D A;  4DV7 E;  1N0V C;  5L3J A;  4FN5 A;  2BA1 G;  2UXB I;  5C0X C;  4OO1 C;  1HNX I;  1UDQ A;  5LMU I;  2CGE A;  2HFS A;  1BKN A;  3OTO I;  2JEB A;  2IOQ A;  2C39 B;  2JE6 B;  3LTO A;  3J81 C;  3M85 D;  4LFA E;  4B3T E;  4X66 I;  5DRP A;  1KIJ A;  4X62 E;  1RHY A;  4HAC A;  4JI6 I;  2CZ9 A;  4KHP E;  4DPX A;  4WUB A;  4JI2 I; 
#chains in the Genus database with same CATH homology
 2VES A;  2GO3 A;  3PS1 A;  2JT2 A;  3NZK A;  4IS9 A;  4LCH A;  4U3D A;  4U3B A;  2O3Z A;  4FW3 A;  4ISA A;  4MDT A;  4LCG A;  4OZE A;  5DRO A;  2J65 A;  1YH8 A;  2GO4 A;  1YHC A;  2IER A;  4FW5 A;  1P42 A;  3P3C A;  4LCF A;  4OKG A;  4FW4 A;  4FW7 A;  4J3D A;  3P76 A;  3PS3 A;  4MQY A;  3UHM A;  5DRP A;  3P3E A;  5DRR A;  1XXE A;  3PS2 A;  3P3G A;  3U1Y A;  4FW6 A;  5DRQ A;  2IES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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