2O3ZA

X-ray crystal structure of lpxc complexed with 3-heptyloxybenzoate
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC.
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 91
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2o3zA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2o3zA02
5DROA 2GO3A 1YH8A 3U1YA 3PS1A 3P76A 2J65A 3P3CA 4FW6A 3P3EA 4FW3A 3P3GA 4J3DA 4ISAA 4OKGA 4OZEA 1XXEA 2IESA 3NZKA 4U3DA 4LCFA 5DRPA 4MDTA 3PS3A 2GO4A 2JT2A 1YHCA 2IERA 4IS9A 4U3BA 4FW7A 3PS2A 4LCGA 3UHMA 4MQYA 2O3ZA 4FW4A 1P42A 2VESA 5DRRA 4LCHA 5DRQA 4FW5A
chains in the Genus database with same CATH superfamily
3QT6A 3D4JA 1H74A 1RR9A 4R1FA 4MYUA 2PO1A 1OYSA 2J65A 4I3HA 1HNXI 1N33E 3ZKDA 2X7IA 1S4EA 3NZKA 3CDJA 1ZM3A 3GONA 4JYAE 5LMUE 2GO4A 4OO1D 4DPWA 5K36F 4BA1B 3K1JA 4LOMA 5K36B 2ZBKB 2Z5BB 5BR8E 1I94I 1FJGE 2WP8A 3WU3A 1R6LA 4OO1B 2WP8B 4DUYE 1MU5A 4JI3E 5DNXA 4DPUA 2HKEA 2XEXA 5IT9C 1HNZI 4X65I 4U3DA 4IFDC 5LMNI 4DV6E 2F4VI 4JV5I 4HACB 2CZ9A 1YHCA 3V2UC 4IZJD 4FW7A 2Z5CB 5FWKA 2JEBA 1ZXNA 2Z5CA 3WU5A 2PO2B 5A2QQ 2UUAE 1Z5CA 5DNLA 4FWHA 5DRRA 4HY1A 1OJ4A 4DR3I 3J7AG 4DR7E 4GKKE 1Z0TA 3QT7A 2E1RA 4LF5I 2UXBE 4Z7CA 2BA0D 1A6FA 4AQYI 1FWLA 3CDIA 4JI7I 4DR4I 2UUCI 1N32I 2E5LI 2BA1D 2IOQA 2VQFE 4OO1A 4DR7I 4MU1A 4XTJA 4LCGA 4PRXA 1XMQI 1Z0VA 4BA1A 4YY3I 4B3ME 3PRYA 2Z5BA 4FW4A 2AE8A 2UUAI 2UU9I 2O1TA 2VESA 4GQUA 4IZKB 2Z5EA 4OO1F 3J80C 4B3SE 3U1YA 5K36D 5K36C 4DV6I 3P3CA 2F4VE 1QZRA 1S16A 2BR2B 2HFUA 4DR1E 2HKJA 2IESA 4DR2E 4M1KA 2HFSA 4JI3I 3HJCA 1R6MA 4MYTA 2Q2EB 1J5EE 1HNWI 4JI8E 4LFCE 4IFDD 3M85D 1NHHA 3J81C 2UXCE 1DARA 1KKHA 4AIDA 2NN6A 1D6TA 3PYEA 2NN6B 2DEIA 3LPSA 2ZM6E 4FN5A 1Z0GA 1XMOE 4OX9E 4DR6E 4DUZI 4IFDA 3QT5A 2WNRA 2ZITA 4EMDA 4BA2B 1Y60A 5L3JA 2O1WA 2A2DA 4OO1C 4JI2E 3Q6MA 4LFBI 1B63A 4HYMA 4DV2I 3Q1QA 4AIMA 2EFGA 1IBME 2LJPA 2BV3A 2PNMA 4LF8E 3B4TA 4N3OA 3OTOE 1XNQI 1Y4UA 4NXNI 3T1YE 1MG7A 4FW3A 2HHHE 1RHYA 4JI6E 4KHPE 2VQEI 4GKJE 4DU7A 3B78A 4MDTA 1XNRE 2V2QA 4DV0E 2VQEE 2HK3A 4JI6I 4YHHI 2HHHI 5JEAC 5ELWA 4U3BA 1IBMI 1Z5AA 2NPFA 3OTOI 5C0XA 4LF8I 3PYFA 4UTGA 4LF6I 4NXMI 1ZM9A 1OYPA 5EL9A 4B3RE 2WW4A 4X66E 1UDQA 2C37A 1Z0CA 4FW9A 2O1VA 2O1UA 4DV7I 1PKPA 3M6AA 4DUZE 4DR6I 1E3HA 2ZM6I 4IS9A 1UDNA 4OX9I 1XMOI 1HK7A 3P06A 2O3ZA 3K17A 4LF4E 3LTOA 4DPYA 5IWAE 4JI8I 5JEAD 1NHJA 2CG9A 3PS1A 1HNWE 4X62E 4DV5E 2V2VA 4DR2I 1J5EI 2PO0B 4DR1I 2UUBI 1UDSA 2BA1G 3K85A 4USMA 4IFDB 2BA0G 4PU9A 1Z0BA 4K0KI 1FWKA 1ZXMA 2JEBB 1HR0E 4B3MI 2IOPA 5DRQA 1Y6ZA 1KTVA 4JI4I 3LNUA 1USVA 1VISA 2J7KA 4YY3E 4IZJA 1XMQE 1N36I 4RPFA 2UXDE 2X36A 1USUA 1N32E 2UUCE 4QNKA 3PYGA 3H1CA 2E5LE 1N0UA 4JI7E 3GLLA 4LF5E 4AQYE 3F0NA 1N36E 2UXBI 3B82A 4DPXA 4DR5E 4JI4E 4GKKI 1P42A 4DR3E 3WU6A 4BA2A 4P52A 4FW5A 5IT9Q 4K0KE 2GO3A 4JG4A 4OO1E 3P3EA 1KVKA 3P3GA 4J3DA 1XXEA 1NHIA 3J81Q 4X65E 3GMEA 2PNLA 4X62I 4DV5I 1PVGA 3HKMA 2NN6F 4DUYI 4IZJB 1FJGI 4WUBA 1IBLI 5IWAI 2A2CA 4ED4A 1ZM4A 1I94E 5FLXQ 3M85G 4ZVIA 5BR8I 5LMUI 5C0XD 1KIJA 4B3TI 4DU8A 4OKGA 4OZEA 1UDOA 4JYAI 4IZKA 4B3TE 4PRVA 1HNXE 5JEAB 1Z0EA 1Y4SA 1H73A 2BM0A 1H7SA 1N33I 3PS2A 4MQYA 1IBLE 2CVEA 2DEJA 1N0VC 2HK2A 4B3RI 1UEKA 3WU4A 1EA6A 1WUUA 1FI4A 4LCHA 2PNZB 4NXME 4AM3A 3QT8A 4LFAE 5C0XC 4JI5I 1VI7A 3M7NG 5K36A 4MU0A 1XNRI 4JI0I 4Z7YA 3ZM7A 2R3VA 4GKJI 2GQ0A 2PO2A 3T1YI 4NXNE 4QNJA 3JAMQ 2C37B 1Y5YA 3T1HE 4DPTA 3GCMA 4HACA 2F1DA 4DR5I 4DV2E 4WUDA 2PO0A 1BKNA 1K47A 5JEAF 1ELOA 2C39A 2JE6A 3L7ZA 5DROA 4LF9E 4MU3A 3P76A 2V34A 4ISAA 5C0XB 1ZM2A 4IFDF 2UXDI 4WUCA 5A2QC 2C38B 5JEAE 2BM1A 4DV3E 4DV1E 3ZZ0A 1HR0I 2JEAB 3J7AM 1MX0A 1EI1A 4X64E 4DV4E 2UXCI 1PIEA 1IBKI 4FWDA 1FNMA 4LFCI 4DXLA 5FLXC 4JI1E 4FW6A 3PYDA 1NZ0A 2UUBE 2PO1B 5GMDA 4LF7E 1N34E 1N34I 1U2RA 1B62A 4LF7I 4LCFA 2C39B 2JE6B 2NN6D 2V8PA 2GS8A 3L7ZB 3PS3A 4P7AA 2JT2A 3ZZTA 2IERA 5JEAA 1FKAE 4NBQA 4JI1I 4B3SI 4FWGA 4DV4I 2R42A 1IBKE 4LF4I 2VF3A 4X64I 1Z0WA 2UU9E 1E3PA 4IFDE 3DD6A 2OI2A 4LPFA 4DV1I 1YH8A 4DV3I 4HXZA 3J80Q 5GMEA 2NN6E 2VQFI 3Q6NA 4MU4A 4DV7E 3H4LA 1OYRA 3B8HA 5DRPA 4DR4E 4X66I 5K36E 5LL6R 3U1KA 3ZZUA 2BR2A 2PNZA 4LF9I 4LF6E 3M7ND 4KQVA 1RREA 3T1HI 1H72C 5C0XF 4YHHE 3KRNA 4DV0I 2JEAA 3ZKBA 1H7UA 2NN6C 2WNRB 2C38A 3HULA 4JI0E 3CWVA 4JV5E 2CGEA 4KHPI 2AJ4A 2V2ZA 5LMNE 3JAMC 1XHKA 4USKA 1HNZE 5EKWA 1XNQE 3V5RA 5C0XE 1Z59A 4JI5E 3UHMA 4URLA 4UT4A 1Z5BA 4LFAI 4LFBE 4JI2I
chains in the Genus database with same CATH topology
5DROA 2GO3A 1YH8A 3U1YA 3PS1A 3P76A 2J65A 3P3CA 4FW6A 3P3EA 4FW3A 3P3GA 4J3DA 4ISAA 4OKGA 4OZEA 1XXEA 2IESA 3NZKA 4U3DA 4LCFA 5DRPA 4MDTA 3PS3A 2GO4A 2JT2A 1YHCA 2IERA 4IS9A 4U3BA 4FW7A 3PS2A 4LCGA 3UHMA 4MQYA 2O3ZA 4FW4A 1P42A 2VESA 5DRRA 4LCHA 5DRQA 4FW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DRO A;  2GO3 A;  1YH8 A;  3U1Y A;  3PS1 A;  3P76 A;  2J65 A;  3P3C A;  4FW6 A;  3P3E A;  4FW3 A;  3P3G A;  4J3D A;  4ISA A;  4OKG A;  4OZE A;  1XXE A;  2IES A;  3NZK A;  4U3D A;  4LCF A;  5DRP A;  4MDT A;  3PS3 A;  2GO4 A;  2JT2 A;  1YHC A;  2IER A;  4IS9 A;  4U3B A;  4FW7 A;  3PS2 A;  4LCG A;  3UHM A;  4MQY A;  2O3Z A;  4FW4 A;  1P42 A;  2VES A;  5DRR A;  4LCH A;  5DRQ A;  4FW5 A; 
#chains in the Genus database with same CATH topology
 3QT6 A;  3D4J A;  1H74 A;  1RR9 A;  4R1F A;  4MYU A;  2PO1 A;  1OYS A;  2J65 A;  4I3H A;  1HNX I;  1N33 E;  3ZKD A;  2X7I A;  1S4E A;  3NZK A;  3CDJ A;  1ZM3 A;  3GON A;  4JYA E;  5LMU E;  2GO4 A;  4OO1 D;  4DPW A;  5K36 F;  4BA1 B;  3K1J A;  4LOM A;  5K36 B;  2ZBK B;  2Z5B B;  5BR8 E;  1I94 I;  1FJG E;  2WP8 A;  3WU3 A;  1R6L A;  4OO1 B;  2WP8 B;  4DUY E;  1MU5 A;  4JI3 E;  5DNX A;  4DPU A;  2HKE A;  2XEX A;  5IT9 C;  1HNZ I;  4X65 I;  4U3D A;  4IFD C;  5LMN I;  4DV6 E;  2F4V I;  4JV5 I;  4HAC B;  2CZ9 A;  1YHC A;  3V2U C;  4IZJ D;  4FW7 A;  2Z5C B;  5FWK A;  2JEB A;  1ZXN A;  2Z5C A;  3WU5 A;  2PO2 B;  5A2Q Q;  2UUA E;  1Z5C A;  5DNL A;  4FWH A;  5DRR A;  4HY1 A;  1OJ4 A;  4DR3 I;  3J7A G;  4DR7 E;  4GKK E;  1Z0T A;  3QT7 A;  2E1R A;  4LF5 I;  2UXB E;  4Z7C A;  2BA0 D;  1A6F A;  4AQY I;  1FWL A;  3CDI A;  4JI7 I;  4DR4 I;  2UUC I;  1N32 I;  2E5L I;  2BA1 D;  2IOQ A;  2VQF E;  4OO1 A;  4DR7 I;  4MU1 A;  4XTJ A;  4LCG A;  4PRX A;  1XMQ I;  1Z0V A;  4BA1 A;  4YY3 I;  4B3M E;  3PRY A;  2Z5B A;  4FW4 A;  2AE8 A;  2UUA I;  2UU9 I;  2O1T A;  2VES A;  4GQU A;  4IZK B;  2Z5E A;  4OO1 F;  3J80 C;  4B3S E;  3U1Y A;  5K36 D;  5K36 C;  4DV6 I;  3P3C A;  2F4V E;  1QZR A;  1S16 A;  2BR2 B;  2HFU A;  4DR1 E;  2HKJ A;  2IES A;  4DR2 E;  4M1K A;  2HFS A;  4JI3 I;  3HJC A;  1R6M A;  4MYT A;  2Q2E B;  1J5E E;  1HNW I;  4JI8 E;  4LFC E;  4IFD D;  3M85 D;  1NHH A;  3J81 C;  2UXC E;  1DAR A;  1KKH A;  4AID A;  2NN6 A;  1D6T A;  3PYE A;  2NN6 B;  2DEI A;  3LPS A;  2ZM6 E;  4FN5 A;  1Z0G A;  1XMO E;  4OX9 E;  4DR6 E;  4DUZ I;  4IFD A;  3QT5 A;  2WNR A;  2ZIT A;  4EMD A;  4BA2 B;  1Y60 A;  5L3J A;  2O1W A;  2A2D A;  4OO1 C;  4JI2 E;  3Q6M A;  4LFB I;  1B63 A;  4HYM A;  4DV2 I;  3Q1Q A;  4AIM A;  2EFG A;  1IBM E;  2LJP A;  2BV3 A;  2PNM A;  4LF8 E;  3B4T A;  4N3O A;  3OTO E;  1XNQ I;  1Y4U A;  4NXN I;  3T1Y E;  1MG7 A;  4FW3 A;  2HHH E;  1RHY A;  4JI6 E;  4KHP E;  2VQE I;  4GKJ E;  4DU7 A;  3B78 A;  4MDT A;  1XNR E;  2V2Q A;  4DV0 E;  2VQE E;  2HK3 A;  4JI6 I;  4YHH I;  2HHH I;  5JEA C;  5ELW A;  4U3B A;  1IBM I;  1Z5A A;  2NPF A;  3OTO I;  5C0X A;  4LF8 I;  3PYF A;  4UTG A;  4LF6 I;  4NXM I;  1ZM9 A;  1OYP A;  5EL9 A;  4B3R E;  2WW4 A;  4X66 E;  1UDQ A;  2C37 A;  1Z0C A;  4FW9 A;  2O1V A;  2O1U A;  4DV7 I;  1PKP A;  3M6A A;  4DUZ E;  4DR6 I;  1E3H A;  2ZM6 I;  4IS9 A;  1UDN A;  4OX9 I;  1XMO I;  1HK7 A;  3P06 A;  2O3Z A;  3K17 A;  4LF4 E;  3LTO A;  4DPY A;  5IWA E;  4JI8 I;  5JEA D;  1NHJ A;  2CG9 A;  3PS1 A;  1HNW E;  4X62 E;  4DV5 E;  2V2V A;  4DR2 I;  1J5E I;  2PO0 B;  4DR1 I;  2UUB I;  1UDS A;  2BA1 G;  3K85 A;  4USM A;  4IFD B;  2BA0 G;  4PU9 A;  1Z0B A;  4K0K I;  1FWK A;  1ZXM A;  2JEB B;  1HR0 E;  4B3M I;  2IOP A;  5DRQ A;  1Y6Z A;  1KTV A;  4JI4 I;  3LNU A;  1USV A;  1VIS A;  2J7K A;  4YY3 E;  4IZJ A;  1XMQ E;  1N36 I;  4RPF A;  2UXD E;  2X36 A;  1USU A;  1N32 E;  2UUC E;  4QNK A;  3PYG A;  3H1C A;  2E5L E;  1N0U A;  4JI7 E;  3GLL A;  4LF5 E;  4AQY E;  3F0N A;  1N36 E;  2UXB I;  3B82 A;  4DPX A;  4DR5 E;  4JI4 E;  4GKK I;  1P42 A;  4DR3 E;  3WU6 A;  4BA2 A;  4P52 A;  4FW5 A;  5IT9 Q;  4K0K E;  2GO3 A;  4JG4 A;  4OO1 E;  3P3E A;  1KVK A;  3P3G A;  4J3D A;  1XXE A;  1NHI A;  3J81 Q;  4X65 E;  3GME A;  2PNL A;  4X62 I;  4DV5 I;  1PVG A;  3HKM A;  2NN6 F;  4DUY I;  4IZJ B;  1FJG I;  4WUB A;  1IBL I;  5IWA I;  2A2C A;  4ED4 A;  1ZM4 A;  1I94 E;  5FLX Q;  3M85 G;  4ZVI A;  5BR8 I;  5LMU I;  5C0X D;  1KIJ A;  4B3T I;  4DU8 A;  4OKG A;  4OZE A;  1UDO A;  4JYA I;  4IZK A;  4B3T E;  4PRV A;  1HNX E;  5JEA B;  1Z0E A;  1Y4S A;  1H73 A;  2BM0 A;  1H7S A;  1N33 I;  3PS2 A;  4MQY A;  1IBL E;  2CVE A;  2DEJ A;  1N0V C;  2HK2 A;  4B3R I;  1UEK A;  3WU4 A;  1EA6 A;  1WUU A;  1FI4 A;  4LCH A;  2PNZ B;  4NXM E;  4AM3 A;  3QT8 A;  4LFA E;  5C0X C;  4JI5 I;  1VI7 A;  3M7N G;  5K36 A;  4MU0 A;  1XNR I;  4JI0 I;  4Z7Y A;  3ZM7 A;  2R3V A;  4GKJ I;  2GQ0 A;  2PO2 A;  3T1Y I;  4NXN E;  4QNJ A;  3JAM Q;  2C37 B;  1Y5Y A;  3T1H E;  4DPT A;  3GCM A;  4HAC A;  2F1D A;  4DR5 I;  4DV2 E;  4WUD A;  2PO0 A;  1BKN A;  1K47 A;  5JEA F;  1ELO A;  2C39 A;  2JE6 A;  3L7Z A;  5DRO A;  4LF9 E;  4MU3 A;  3P76 A;  2V34 A;  4ISA A;  5C0X B;  1ZM2 A;  4IFD F;  2UXD I;  4WUC A;  5A2Q C;  2C38 B;  5JEA E;  2BM1 A;  4DV3 E;  4DV1 E;  3ZZ0 A;  1HR0 I;  2JEA B;  3J7A M;  1MX0 A;  1EI1 A;  4X64 E;  4DV4 E;  2UXC I;  1PIE A;  1IBK I;  4FWD A;  1FNM A;  4LFC I;  4DXL A;  5FLX C;  4JI1 E;  4FW6 A;  3PYD A;  1NZ0 A;  2UUB E;  2PO1 B;  5GMD A;  4LF7 E;  1N34 E;  1N34 I;  1U2R A;  1B62 A;  4LF7 I;  4LCF A;  2C39 B;  2JE6 B;  2NN6 D;  2V8P A;  2GS8 A;  3L7Z B;  3PS3 A;  4P7A A;  2JT2 A;  3ZZT A;  2IER A;  5JEA A;  1FKA E;  4NBQ A;  4JI1 I;  4B3S I;  4FWG A;  4DV4 I;  2R42 A;  1IBK E;  4LF4 I;  2VF3 A;  4X64 I;  1Z0W A;  2UU9 E;  1E3P A;  4IFD E;  3DD6 A;  2OI2 A;  4LPF A;  4DV1 I;  1YH8 A;  4DV3 I;  4HXZ A;  3J80 Q;  5GME A;  2NN6 E;  2VQF I;  3Q6N A;  4MU4 A;  4DV7 E;  3H4L A;  1OYR A;  3B8H A;  5DRP A;  4DR4 E;  4X66 I;  5K36 E;  5LL6 R;  3U1K A;  3ZZU A;  2BR2 A;  2PNZ A;  4LF9 I;  4LF6 E;  3M7N D;  4KQV A;  1RRE A;  3T1H I;  1H72 C;  5C0X F;  4YHH E;  3KRN A;  4DV0 I;  2JEA A;  3ZKB A;  1H7U A;  2NN6 C;  2WNR B;  2C38 A;  3HUL A;  4JI0 E;  3CWV A;  4JV5 E;  2CGE A;  4KHP I;  2AJ4 A;  2V2Z A;  5LMN E;  3JAM C;  1XHK A;  4USK A;  1HNZ E;  5EKW A;  1XNQ E;  3V5R A;  5C0X E;  1Z59 A;  4JI5 E;  3UHM A;  4URL A;  4UT4 A;  1Z5B A;  4LFA I;  4LFB E;  4JI2 I; 
#chains in the Genus database with same CATH homology
 5DRO A;  2GO3 A;  1YH8 A;  3U1Y A;  3PS1 A;  3P76 A;  2J65 A;  3P3C A;  4FW6 A;  3P3E A;  4FW3 A;  3P3G A;  4J3D A;  4ISA A;  4OKG A;  4OZE A;  1XXE A;  2IES A;  3NZK A;  4U3D A;  4LCF A;  5DRP A;  4MDT A;  3PS3 A;  2GO4 A;  2JT2 A;  1YHC A;  2IER A;  4IS9 A;  4U3B A;  4FW7 A;  3PS2 A;  4LCG A;  3UHM A;  4MQY A;  2O3Z A;  4FW4 A;  1P42 A;  2VES A;  5DRR A;  4LCH A;  5DRQ A;  4FW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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