4QNKA

The structure of wt a. thaliana igpd2 in complex with mn2+ and phosphate
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
185
structure length
185
Chain Sequence
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
total genus 58
structure length 185
sequence length 185
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2014-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4qnkA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4qnkA02
2F1DA 5DNXA 4QNKA 4MU0A 4MU3A 4MU4A 4LOMA 5DNLA 5ELWA 5EKWA 1RHYA 5EL9A 4MU1A 4LPFA 4QNJA 2AE8A 4GQUA
chains in the Genus database with same CATH superfamily
4X62E 2O1WA 3P3EA 4LFAI 1N0UA 4LF8E 4X65E 4LF5I 4OO1E 1E3HA 4GKJI 4JI5E 3PS2A 1PVGA 3ZM7A 1P42A 3CWVA 3GONA 1UDNA 4HACA 4AQYE 1N36I 4NXMI 1ZXNA 2PO1A 2A2DA 1Z5AA 4JI8I 4U3BA 4N3OA 4FW6A 3Q6NA 4UT4A 2R42A 4QNJA 3OTOE 1USUA 1XXEA 4LF9E 4JV5E 1Y6ZA 1YH8A 3K17A 1Z0EA 4ZVIA 4FWGA 1UDOA 3T1HI 2HHHE 4FW5A 1FNMA 4DV5E 1PIEA 5A2QC 1HNZI 4LF6E 5DRRA 2IOQA 1Y4UA 4JI0I 1N32I 3ZKDA 2WP8B 3LPSA 1B62A 4FW9A 4JI4E 4OX9I 4HYMA 1VI7A 4DV2E 4MQYA 3UHMA 2DEJA 4IZJA 2JEBA 3DD6A 3P76A 4LFBE 3HKMA 2O1VA 2A2CA 1NZ0A 2NN6F 4LF4E 2CZ9A 4X65I 2CG9A 1BKNA 4IZKB 2O1TA 4DR1E 4RPFA 5C0XA 2BA1D 2AE8A 1OJ4A 4BA1A 4P7AA 4DV6I 4B3MI 1Z0BA 5EKWA 3WU6A 3T1YE 1E3PA 4Z7CA 1FKAE 5IT9C 4OO1C 1Z5CA 4KHPI 4KQVA 2JT2A 2Z5EA 1FWKA 3K85A 3GMEA 2AJ4A 4LFAE 5K36B 2PO0A 1HK7A 4X62I 1R6LA 4DR1I 2NN6A 1Y60A 4MYTA 2NN6B 2C39B 4USKA 2ZM6I 4BA2A 5JEAF 1FWLA 1Z5BA 4IFDC 3H1CA 4EMDA 3V2UC 4DR2I 1HNWI 1MU5A 2VQEI 2J7KA 2HKEA 4FW3A 3L7ZB 5DNLA 2C39A 4LFCI 2BV3A 4DUYE 2UUAE 5GMEA 4JI1I 1NHHA 2UXDE 4DV7E 4OO1F 4MU3A 3ZZUA 3Q6MA 1Z0GA 2IESA 3F0NA 1HNZE 4LF6I 1ZM4A 5C0XE 5JEAE 2R3VA 2NN6E 2IERA 3M85G 4PRVA 3P06A 4NBQA 4XTJA 1Z0TA 1HR0E 2UUBI 4LF4I 4GQUA 5C0XB 3QT5A 4MU4A 2V34A 4IZKA 1N0VC 1KKHA 2BM0A 1Z0CA 4DV7I 4DV2I 2Z5BB 1N36E 4NXME 5FLXC 4JI4I 2CVEA 4B3RE 3M6AA 5K36F 4B3RI 2WNRA 4DV3I 2X36A 3KRNA 2GS8A 4DXLA 1Z59A 1N34I 2WW4A 3QT7A 3HJCA 2BA0G 4WUCA 2GO4A 3PYDA 4LCHA 4UTGA 1MG7A 1IBMI 1Z0WA 1ZXMA 3GLLA 4DV5I 2F4VE 1RR9A 2C37A 4IS9A 4BA1B 3M7ND 1H72C 4OO1D 3WU3A 4FN5A 4LCFA 1PKPA 1VISA 3ZKBA 1KVKA 4OKGA 1NHIA 3HULA 4JI7E 2PO1B 4MU0A 5IWAI 3D4JA 2JEBB 2VQFI 4JI5I 4B3TI 5JEAD 2VQFE 1XNRI 4JI3I 2OI2A 1XMOE 3B78A 4OZEA 4HXZA 2PNLA 3WU4A 4IFDF 1OYPA 5GMDA 4IFDE 1MX0A 4DR3E 4DPXA 4YHHI 4JI6E 2BM1A 4USMA 4DV1E 4YY3E 2HK3A 1QZRA 2V8PA 4PRXA 2GQ0A 2UXDI 3PRYA 1ZM9A 4DR5I 1H7UA 4IZJB 2F4VI 1J5EE 4DPYA 1A6FA 2BA0D 3J81Q 4LFCE 3M85D 4MU1A 2UXCE 1Y4SA 2UU9I 4DR7E 2PO2A 4JG4A 3B4TA 2V2ZA 1S16A 1XNQI 5DNXA 4QNKA 4I3HA 4MDTA 2BA1G 1H73A 4J3DA 2DEIA 5LMUE 4NXNE 4GKKI 1I94I 4JI3E 2CGEA 4P52A 4OX9E 4LF7I 5JEAB 4B3TE 1OYRA 4X66I 1FJGI 2UXBE 1RHYA 2VESA 2PNMA 2UUBE 3QT8A 1XMQE 1WUUA 4JI2E 2F1DA 4DUZI 4DR6E 2EFGA 4DR4E 2HK2A 2Z5BA 2O3ZA 1IBKE 1UEKA 4DR7I 3L7ZA 3CDJA 4FW7A 5IT9Q 2UU9E 2HFSA 2UXCI 2ZBKB 3JAMQ 4JV5I 4IZJD 3V5RA 1OYSA 3H4LA 3OTOI 4JI8E 1D6TA 1USVA 1FJGE 5L3JA 3M7NG 2O1UA 2PNZB 2JE6B 4LF7E 3B8HA 2NPFA 2V2VA 4DUZE 1RREA 1XMQI 1HNXI 4DV4I 4DR2E 2C38B 1UDQA 5EL9A 1N32E 1K47A 4ISAA 3Q1QA 3ZZ0A 2ZM6E 2HHHI 1XMOI 2JEAA 3T1HE 2VF3A 1HR0I 1B63A 5DRQA 5BR8I 4DPUA 1N33I 4JYAI 3K1JA 1J5EI 2X7IA 4DV4E 4URLA 5IWAE 4BA2B 4WUDA 3PYFA 4FWHA 3GCMA 2PNZA 2UUCE 3CDIA 5K36E 4B3ME 1YHCA 4DR5E 2J65A 4X64E 3U1KA 1KTVA 4LF8I 4IFDB 4YHHE 4JI6I 4Z7YA 1XHKA 5LL6R 2Z5CB 4LOMA 5DRPA 4B3SE 2Z5CA 4M1KA 1Y5YA 5BR8E 1N33E 2UXBI 2JEAB 4K0KI 1HNWE 2JE6A 4DV0E 2LJPA 1N34E 5C0XF 3J7AM 4HY1A 4DPTA 3J80Q 2C38A 5LMNI 1KIJA 4X66E 4AM3A 4FWDA 1EI1A 2BR2B 4MYUA 4IFDA 2E5LI 5FWKA 4JI7I 4KHPE 4GKKE 1S4EA 4NXNI 5LMUI 1Z0VA 3PYGA 1IBLI 3NZKA 3JAMC 3WU5A 3J80C 5K36A 1IBME 2WP8A 1DARA 4FW4A 3PS1A 4LPFA 3J81C 2XEXA 4DR4I 4DR6I 4DV6E 4X64I 2E5LE 3LTOA 2NN6C 4IFDD 4JI1E 4DR3I 5C0XC 1IBKI 4DUYI 5LMNE 5A2QQ 4DV1I 5K36C 2PO0B 3J7AG 4JI2I 4AQYI 4DU7A 1H74A 2E1RA 4K0KE 5K36D 3LNUA 2VQEE 4R1FA 2Q2EB 4JI0E 4AIDA 4GKJE 4HACB 5C0XD 4LF5E 1NHJA 3ZZTA 2NN6D 1I94E 1ZM2A 4OO1A 1U2RA 5JEAC 2WNRB 3PS3A 4DPWA 5FLXQ 1XNQE 1H7SA 3QT6A 3U1YA 1HNXE 1IBLE 3PYEA 1EA6A 4U3DA 5DROA 3T1YI 4YY3I 1UDSA 5JEAA 5ELWA 3P3CA 4LF9I 1ELOA 2ZITA 2UUCI 3B82A 4JYAE 4AIMA 4DU8A 4LCGA 2C37B 2GO3A 3P3GA 4DV0I 4ED4A 2UUAI 4OO1B 1FI4A 2V2QA 1XNRE 1ZM3A 4WUBA 2BR2A 4PU9A 2PO2B 4DV3E 2IOPA 4B3SI 2HKJA 2HFUA 1R6MA 4LFBI
chains in the Genus database with same CATH topology
2F1DA 5DNXA 4QNKA 4MU0A 4MU3A 4MU4A 4LOMA 5DNLA 5ELWA 5EKWA 1RHYA 5EL9A 4MU1A 4LPFA 4QNJA 2AE8A 4GQUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1D A;  5DNX A;  4QNK A;  4MU0 A;  4MU3 A;  4MU4 A;  4LOM A;  5DNL A;  5ELW A;  5EKW A;  1RHY A;  5EL9 A;  4MU1 A;  4LPF A;  4QNJ A;  2AE8 A;  4GQU A; 
#chains in the Genus database with same CATH topology
 4X62 E;  2O1W A;  3P3E A;  4LFA I;  1N0U A;  4LF8 E;  4X65 E;  4LF5 I;  4OO1 E;  1E3H A;  4GKJ I;  4JI5 E;  3PS2 A;  1PVG A;  3ZM7 A;  1P42 A;  3CWV A;  3GON A;  1UDN A;  4HAC A;  4AQY E;  1N36 I;  4NXM I;  1ZXN A;  2PO1 A;  2A2D A;  1Z5A A;  4JI8 I;  4U3B A;  4N3O A;  4FW6 A;  3Q6N A;  4UT4 A;  2R42 A;  4QNJ A;  3OTO E;  1USU A;  1XXE A;  4LF9 E;  4JV5 E;  1Y6Z A;  1YH8 A;  3K17 A;  1Z0E A;  4ZVI A;  4FWG A;  1UDO A;  3T1H I;  2HHH E;  4FW5 A;  1FNM A;  4DV5 E;  1PIE A;  5A2Q C;  1HNZ I;  4LF6 E;  5DRR A;  2IOQ A;  1Y4U A;  4JI0 I;  1N32 I;  3ZKD A;  2WP8 B;  3LPS A;  1B62 A;  4FW9 A;  4JI4 E;  4OX9 I;  4HYM A;  1VI7 A;  4DV2 E;  4MQY A;  3UHM A;  2DEJ A;  4IZJ A;  2JEB A;  3DD6 A;  3P76 A;  4LFB E;  3HKM A;  2O1V A;  2A2C A;  1NZ0 A;  2NN6 F;  4LF4 E;  2CZ9 A;  4X65 I;  2CG9 A;  1BKN A;  4IZK B;  2O1T A;  4DR1 E;  4RPF A;  5C0X A;  2BA1 D;  2AE8 A;  1OJ4 A;  4BA1 A;  4P7A A;  4DV6 I;  4B3M I;  1Z0B A;  5EKW A;  3WU6 A;  3T1Y E;  1E3P A;  4Z7C A;  1FKA E;  5IT9 C;  4OO1 C;  1Z5C A;  4KHP I;  4KQV A;  2JT2 A;  2Z5E A;  1FWK A;  3K85 A;  3GME A;  2AJ4 A;  4LFA E;  5K36 B;  2PO0 A;  1HK7 A;  4X62 I;  1R6L A;  4DR1 I;  2NN6 A;  1Y60 A;  4MYT A;  2NN6 B;  2C39 B;  4USK A;  2ZM6 I;  4BA2 A;  5JEA F;  1FWL A;  1Z5B A;  4IFD C;  3H1C A;  4EMD A;  3V2U C;  4DR2 I;  1HNW I;  1MU5 A;  2VQE I;  2J7K A;  2HKE A;  4FW3 A;  3L7Z B;  5DNL A;  2C39 A;  4LFC I;  2BV3 A;  4DUY E;  2UUA E;  5GME A;  4JI1 I;  1NHH A;  2UXD E;  4DV7 E;  4OO1 F;  4MU3 A;  3ZZU A;  3Q6M A;  1Z0G A;  2IES A;  3F0N A;  1HNZ E;  4LF6 I;  1ZM4 A;  5C0X E;  5JEA E;  2R3V A;  2NN6 E;  2IER A;  3M85 G;  4PRV A;  3P06 A;  4NBQ A;  4XTJ A;  1Z0T A;  1HR0 E;  2UUB I;  4LF4 I;  4GQU A;  5C0X B;  3QT5 A;  4MU4 A;  2V34 A;  4IZK A;  1N0V C;  1KKH A;  2BM0 A;  1Z0C A;  4DV7 I;  4DV2 I;  2Z5B B;  1N36 E;  4NXM E;  5FLX C;  4JI4 I;  2CVE A;  4B3R E;  3M6A A;  5K36 F;  4B3R I;  2WNR A;  4DV3 I;  2X36 A;  3KRN A;  2GS8 A;  4DXL A;  1Z59 A;  1N34 I;  2WW4 A;  3QT7 A;  3HJC A;  2BA0 G;  4WUC A;  2GO4 A;  3PYD A;  4LCH A;  4UTG A;  1MG7 A;  1IBM I;  1Z0W A;  1ZXM A;  3GLL A;  4DV5 I;  2F4V E;  1RR9 A;  2C37 A;  4IS9 A;  4BA1 B;  3M7N D;  1H72 C;  4OO1 D;  3WU3 A;  4FN5 A;  4LCF A;  1PKP A;  1VIS A;  3ZKB A;  1KVK A;  4OKG A;  1NHI A;  3HUL A;  4JI7 E;  2PO1 B;  4MU0 A;  5IWA I;  3D4J A;  2JEB B;  2VQF I;  4JI5 I;  4B3T I;  5JEA D;  2VQF E;  1XNR I;  4JI3 I;  2OI2 A;  1XMO E;  3B78 A;  4OZE A;  4HXZ A;  2PNL A;  3WU4 A;  4IFD F;  1OYP A;  5GMD A;  4IFD E;  1MX0 A;  4DR3 E;  4DPX A;  4YHH I;  4JI6 E;  2BM1 A;  4USM A;  4DV1 E;  4YY3 E;  2HK3 A;  1QZR A;  2V8P A;  4PRX A;  2GQ0 A;  2UXD I;  3PRY A;  1ZM9 A;  4DR5 I;  1H7U A;  4IZJ B;  2F4V I;  1J5E E;  4DPY A;  1A6F A;  2BA0 D;  3J81 Q;  4LFC E;  3M85 D;  4MU1 A;  2UXC E;  1Y4S A;  2UU9 I;  4DR7 E;  2PO2 A;  4JG4 A;  3B4T A;  2V2Z A;  1S16 A;  1XNQ I;  5DNX A;  4QNK A;  4I3H A;  4MDT A;  2BA1 G;  1H73 A;  4J3D A;  2DEI A;  5LMU E;  4NXN E;  4GKK I;  1I94 I;  4JI3 E;  2CGE A;  4P52 A;  4OX9 E;  4LF7 I;  5JEA B;  4B3T E;  1OYR A;  4X66 I;  1FJG I;  2UXB E;  1RHY A;  2VES A;  2PNM A;  2UUB E;  3QT8 A;  1XMQ E;  1WUU A;  4JI2 E;  2F1D A;  4DUZ I;  4DR6 E;  2EFG A;  4DR4 E;  2HK2 A;  2Z5B A;  2O3Z A;  1IBK E;  1UEK A;  4DR7 I;  3L7Z A;  3CDJ A;  4FW7 A;  5IT9 Q;  2UU9 E;  2HFS A;  2UXC I;  2ZBK B;  3JAM Q;  4JV5 I;  4IZJ D;  3V5R A;  1OYS A;  3H4L A;  3OTO I;  4JI8 E;  1D6T A;  1USV A;  1FJG E;  5L3J A;  3M7N G;  2O1U A;  2PNZ B;  2JE6 B;  4LF7 E;  3B8H A;  2NPF A;  2V2V A;  4DUZ E;  1RRE A;  1XMQ I;  1HNX I;  4DV4 I;  4DR2 E;  2C38 B;  1UDQ A;  5EL9 A;  1N32 E;  1K47 A;  4ISA A;  3Q1Q A;  3ZZ0 A;  2ZM6 E;  2HHH I;  1XMO I;  2JEA A;  3T1H E;  2VF3 A;  1HR0 I;  1B63 A;  5DRQ A;  5BR8 I;  4DPU A;  1N33 I;  4JYA I;  3K1J A;  1J5E I;  2X7I A;  4DV4 E;  4URL A;  5IWA E;  4BA2 B;  4WUD A;  3PYF A;  4FWH A;  3GCM A;  2PNZ A;  2UUC E;  3CDI A;  5K36 E;  4B3M E;  1YHC A;  4DR5 E;  2J65 A;  4X64 E;  3U1K A;  1KTV A;  4LF8 I;  4IFD B;  4YHH E;  4JI6 I;  4Z7Y A;  1XHK A;  5LL6 R;  2Z5C B;  4LOM A;  5DRP A;  4B3S E;  2Z5C A;  4M1K A;  1Y5Y A;  5BR8 E;  1N33 E;  2UXB I;  2JEA B;  4K0K I;  1HNW E;  2JE6 A;  4DV0 E;  2LJP A;  1N34 E;  5C0X F;  3J7A M;  4HY1 A;  4DPT A;  3J80 Q;  2C38 A;  5LMN I;  1KIJ A;  4X66 E;  4AM3 A;  4FWD A;  1EI1 A;  2BR2 B;  4MYU A;  4IFD A;  2E5L I;  5FWK A;  4JI7 I;  4KHP E;  4GKK E;  1S4E A;  4NXN I;  5LMU I;  1Z0V A;  3PYG A;  1IBL I;  3NZK A;  3JAM C;  3WU5 A;  3J80 C;  5K36 A;  1IBM E;  2WP8 A;  1DAR A;  4FW4 A;  3PS1 A;  4LPF A;  3J81 C;  2XEX A;  4DR4 I;  4DR6 I;  4DV6 E;  4X64 I;  2E5L E;  3LTO A;  2NN6 C;  4IFD D;  4JI1 E;  4DR3 I;  5C0X C;  1IBK I;  4DUY I;  5LMN E;  5A2Q Q;  4DV1 I;  5K36 C;  2PO0 B;  3J7A G;  4JI2 I;  4AQY I;  4DU7 A;  1H74 A;  2E1R A;  4K0K E;  5K36 D;  3LNU A;  2VQE E;  4R1F A;  2Q2E B;  4JI0 E;  4AID A;  4GKJ E;  4HAC B;  5C0X D;  4LF5 E;  1NHJ A;  3ZZT A;  2NN6 D;  1I94 E;  1ZM2 A;  4OO1 A;  1U2R A;  5JEA C;  2WNR B;  3PS3 A;  4DPW A;  5FLX Q;  1XNQ E;  1H7S A;  3QT6 A;  3U1Y A;  1HNX E;  1IBL E;  3PYE A;  1EA6 A;  4U3D A;  5DRO A;  3T1Y I;  4YY3 I;  1UDS A;  5JEA A;  5ELW A;  3P3C A;  4LF9 I;  1ELO A;  2ZIT A;  2UUC I;  3B82 A;  4JYA E;  4AIM A;  4DU8 A;  4LCG A;  2C37 B;  2GO3 A;  3P3G A;  4DV0 I;  4ED4 A;  2UUA I;  4OO1 B;  1FI4 A;  2V2Q A;  1XNR E;  1ZM3 A;  4WUB A;  2BR2 A;  4PU9 A;  2PO2 B;  4DV3 E;  2IOP A;  4B3S I;  2HKJ A;  2HFU A;  1R6M A;  4LFB I; 
#chains in the Genus database with same CATH homology
 2F1D A;  5DNX A;  4QNK A;  4MU0 A;  4MU3 A;  4MU4 A;  4LOM A;  5DNL A;  5ELW A;  5EKW A;  1RHY A;  5EL9 A;  4MU1 A;  4LPF A;  4QNJ A;  2AE8 A;  4GQU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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