4QNKA

The structure of wt a. thaliana igpd2 in complex with mn2+ and phosphate
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
185
structure length
185
Chain Sequence
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
total genus 58
structure length 185
sequence length 185
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2014-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4qnkA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4qnkA02
5ELWA 5DNXA 4QNJA 1RHYA 4QNKA 2AE8A 5DNLA 4MU3A 4GQUA 5EL9A 4LPFA 4LOMA 4MU0A 4MU1A 2F1DA 5EKWA 4MU4A
chains in the Genus database with same CATH superfamily
3T1YI 1IBKI 3LTOA 1I94I 1FWKA 4OO1D 3K17A 3KRNA 4DV6E 4KHPI 1PVGA 2E5LI 3GMEA 1DARA 3U1KA 4K0KI 4IZJD 2DEIA 4QNJA 4DV2I 1NHJA 5DNLA 4AIDA 3HJCA 5FLXQ 2C37B 3B8HA 5DNXA 4BA1A 2VESA 2UXBE 1VISA 4DV5I 2R42A 2C38A 1RREA 2NPFA 4MYTA 1B63A 1XXEA 2V2QA 3H1CA 5C0XE 2PNMA 3CDIA 4LCHA 4ZVIA 3WU3A 1UDSA 1XNQE 2C39A 2JT2A 4USMA 4DR7I 4IFDB 1E3HA 1XHKA 2JEAA 1OYSA 4ISAA 4LFCE 4B3RE 1USUA 2E1RA 4DU7A 3QT5A 1H7UA 3LNUA 5LMNE 3PS2A 4DR5I 2EFGA 5K36E 3PS3A 4DUYE 1HNWE 4NXNI 1RHYA 4IFDE 5IT9C 4X64I 1MX0A 4BA2A 1Z0WA 4DV5E 4FWDA 1KVKA 2NN6C 3QT6A 2GS8A 2IOPA 4X65E 2JE6B 3PRYA 4X62I 3B78A 2X7IA 2A2DA 4U3DA 2V8PA 1R6LA 4GKJI 4DV3E 4YHHE 2IOQA 1Y5YA 4USKA 4DPTA 4UTGA 3WU6A 4YHHI 4YY3I 1J5EE 4IZJB 3M7NG 4JYAI 4HXZA 5C0XF 3J81C 3Q6MA 4OO1A 1H7SA 5A2QC 5DROA 2WP8B 2CVEA 5JEAA 3L7ZA 4DUZI 4P7AA 4DR2I 1FJGI 1VI7A 4PU9A 4DR1E 4B3SI 4LF6E 1FWLA 4DV0I 3PYFA 4NXNE 4DR3I 1NZ0A 5LMNI 2O1WA 2PNZB 2O1UA 2UU9I 1FNMA 1HNWI 3J80C 4UT4A 1HK7A 1I94E 1N32E 3P3CA 3M85D 4OO1F 4IZJA 5K36F 3ZKBA 2J7KA 4JI0I 4OO1C 2WP8A 4Z7CA 5A2QQ 2J65A 4LF4I 1KKHA 1RR9A 4B3TI 3UHMA 2JE6A 5JEAC 4X66I 4JI5E 4DR4E 4WUDA 3HULA 1B62A 4FN5A 4DXLA 4X62E 1FI4A 4LFBI 1OJ4A 4DV7E 4FW4A 4M1KA 4AQYI 1Z0GA 2BR2A 4ED4A 2Q2EB 3QT7A 1XMQI 3PS1A 4B3RI 4OKGA 4XTJA 1XMQE 4NXMI 3L7ZB 4J3DA 1YH8A 2HHHE 2WNRA 4FW5A 2UXCI 1HNZI 2HFSA 4AIMA 4DV2E 2GO3A 3QT8A 4FW6A 3Q6NA 1Y60A 4QNKA 2UUAI 2BR2B 1ZM3A 4X66E 2F4VI 4DR6E 3J7AM 1Z5BA 4DV3I 1MG7A 2PNLA 1HR0I 2UU9E 1PIEA 1HR0E 1USVA 4YY3E 2BA1D 2BA0D 2O3ZA 2PO0A 1BKNA 2HK3A 2Z5BB 1H72C 2JEBA 4HACB 4MYUA 4OZEA 5DRRA 2IESA 3WU5A 3PYEA 1EA6A 4LPFA 3F0NA 1N33I 4NBQA 2R3VA 3J81Q 2CZ9A 4DR3E 4IFDD 4X65I 1Z0EA 1UDOA 5L3JA 3M85G 4LF8I 2HHHI 4GKJE 4DR2E 1FJGE 5C0XD 1YHCA 1N34E 3B4TA 1Z5CA 2UUCE 3WU4A 1N34I 1NHHA 1MU5A 4B3ME 2Z5BA 4DR5E 4DPYA 4DV4E 1HNXE 4JG4A 4HY1A 1K47A 2VQEE 1OYRA 4IS9A 3DD6A 4Z7YA 4DPUA 1N0VC 1Z59A 1Y4SA 2O1TA 2WW4A 4N3OA 2VQFI 4DU8A 3CDJA 4FW9A 4JI6E 3P06A 4MU4A 2BM0A 2V34A 4MQYA 3PYDA 1A6FA 4JI7E 4I3HA 4OO1B 4PRVA 1ZM2A 2CG9A 5JEAB 3J80Q 4GKKE 4DR6I 2AJ4A 4DV7I 5C0XC 1IBME 1IBLE 3PYGA 4LFBE 1H73A 2C39B 3GONA 4IFDA 2CGEA 3CWVA 1HNZE 3ZZUA 4B3MI 1U2RA 5FWKA 2F1DA 2X36A 3P3GA 1N36E 3JAMQ 4DR4I 2UXCE 4LF8E 4FWGA 5JEAD 4DR1I 4AQYE 5IWAE 2ZBKB 4MU3A 1KIJA 2V2ZA 4LOMA 4R1FA 2BA0G 3T1YE 2E5LE 3K1JA 3J7AG 4JI2I 2BM1A 1UEKA 5BR8I 5DRPA 2UXDE 5K36C 4OX9I 4JI2E 5K36D 3H4LA 5C0XA 3M6AA 4LF9I 4IFDC 3ZKDA 2GO4A 2OI2A 1D6TA 3V5RA 2NN6E 4JI5I 1WUUA 4LF4E 3T1HE 2GQ0A 2NN6B 2DEJA 1ZXMA 2HK2A 4AM3A 2LJPA 2Z5EA 3K85A 2UUBI 1XMOI 2NN6F 2HFUA 2UUCI 1Y6ZA 5K36A 2PO1A 4JV5E 5GMDA 1S4EA 4MU1A 4DPXA 2BA1G 2V2VA 4WUBA 5DRQA 4LFAI 4FWHA 1Y4UA 2PNZA 4LF6I 4MU0A 1PKPA 4FW7A 4JI1I 1Z5AA 1XNRI 1N33E 4OX9E 4LCGA 3ZZ0A 3OTOE 3OTOI 3GCMA 5LMUE 4DV1I 3NZKA 1Z0VA 2VQEI 2C37A 2UUAE 1Z0CA 3M7ND 4DR7E 5JEAF 4LF7I 5EL9A 1Z0TA 2UXDI 4JI8I 1R6MA 3GLLA 5K36B 2XEXA 4MDTA 2HKEA 3T1HI 2NN6A 2F4VE 4OO1E 4JI3I 4DUYI 4URLA 4WUCA 2UXBI 3V2UC 5JEAE 3U1YA 3LPSA 2C38B 1N0UA 4JI4I 2IERA 1NHIA 1Z0BA 4GKKI 4LF5E 2BV3A 4RPFA 4BA2B 1OYPA 2PO1B 1ELOA 1ZM9A 1KTVA 4B3SE 4DPWA 1IBLI 1QZRA 1IBKE 4PRXA 4DUZE 4NXME 2JEAB 5FLXC 5LL6R 4LFCI 2Z5CB 3JAMC 2VQFE 5GMEA 2PO0B 4LCFA 1XNQI 4JI6I 1HNXI 2HKJA 4IZKA 4KQVA 5IWAI 2PO2B 4LF7E 4DV4I 5BR8E 4GQUA 5LMUI 4DV1E 4JI1E 4DV6I 1N32I 4JI8E 3P3EA 4B3TE 4K0KE 4EMDA 1P42A 5IT9Q 4IFDF 4JI4E 2WNRB 3D4JA 1S16A 4KHPE 3B82A 4JI7I 4JI0E 2ZM6E 4LF5I 3ZZTA 1XMOE 4X64E 4JI3E 1H74A 1UDQA 2ZM6I 1E3PA 2ZITA 5C0XB 4JYAE 4LFAE 3P76A 4P52A 1ZXNA 2PO2A 4FW3A 1XNRE 1IBMI 2NN6D 4HYMA 2VF3A 2AE8A 3Q1QA 2Z5CA 1FKAE 4DV0E 3HKMA 5ELWA 1EI1A 4U3BA 5EKWA 1ZM4A 1J5EI 2UUBE 4BA1B 3ZM7A 2JEBB 4LF9E 4HACA 2A2CA 4IZKB 4JV5I 1UDNA 2O1VA 1N36I
chains in the Genus database with same CATH topology
5ELWA 5DNXA 4QNJA 1RHYA 4QNKA 2AE8A 5DNLA 4MU3A 4GQUA 5EL9A 4LPFA 4LOMA 4MU0A 4MU1A 2F1DA 5EKWA 4MU4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5ELW A;  5DNX A;  4QNJ A;  1RHY A;  4QNK A;  2AE8 A;  5DNL A;  4MU3 A;  4GQU A;  5EL9 A;  4LPF A;  4LOM A;  4MU0 A;  4MU1 A;  2F1D A;  5EKW A;  4MU4 A; 
#chains in the Genus database with same CATH topology
 3T1Y I;  1IBK I;  3LTO A;  1I94 I;  1FWK A;  4OO1 D;  3K17 A;  3KRN A;  4DV6 E;  4KHP I;  1PVG A;  2E5L I;  3GME A;  1DAR A;  3U1K A;  4K0K I;  4IZJ D;  2DEI A;  4QNJ A;  4DV2 I;  1NHJ A;  5DNL A;  4AID A;  3HJC A;  5FLX Q;  2C37 B;  3B8H A;  5DNX A;  4BA1 A;  2VES A;  2UXB E;  1VIS A;  4DV5 I;  2R42 A;  2C38 A;  1RRE A;  2NPF A;  4MYT A;  1B63 A;  1XXE A;  2V2Q A;  3H1C A;  5C0X E;  2PNM A;  3CDI A;  4LCH A;  4ZVI A;  3WU3 A;  1UDS A;  1XNQ E;  2C39 A;  2JT2 A;  4USM A;  4DR7 I;  4IFD B;  1E3H A;  1XHK A;  2JEA A;  1OYS A;  4ISA A;  4LFC E;  4B3R E;  1USU A;  2E1R A;  4DU7 A;  3QT5 A;  1H7U A;  3LNU A;  5LMN E;  3PS2 A;  4DR5 I;  2EFG A;  5K36 E;  3PS3 A;  4DUY E;  1HNW E;  4NXN I;  1RHY A;  4IFD E;  5IT9 C;  4X64 I;  1MX0 A;  4BA2 A;  1Z0W A;  4DV5 E;  4FWD A;  1KVK A;  2NN6 C;  3QT6 A;  2GS8 A;  2IOP A;  4X65 E;  2JE6 B;  3PRY A;  4X62 I;  3B78 A;  2X7I A;  2A2D A;  4U3D A;  2V8P A;  1R6L A;  4GKJ I;  4DV3 E;  4YHH E;  2IOQ A;  1Y5Y A;  4USK A;  4DPT A;  4UTG A;  3WU6 A;  4YHH I;  4YY3 I;  1J5E E;  4IZJ B;  3M7N G;  4JYA I;  4HXZ A;  5C0X F;  3J81 C;  3Q6M A;  4OO1 A;  1H7S A;  5A2Q C;  5DRO A;  2WP8 B;  2CVE A;  5JEA A;  3L7Z A;  4DUZ I;  4P7A A;  4DR2 I;  1FJG I;  1VI7 A;  4PU9 A;  4DR1 E;  4B3S I;  4LF6 E;  1FWL A;  4DV0 I;  3PYF A;  4NXN E;  4DR3 I;  1NZ0 A;  5LMN I;  2O1W A;  2PNZ B;  2O1U A;  2UU9 I;  1FNM A;  1HNW I;  3J80 C;  4UT4 A;  1HK7 A;  1I94 E;  1N32 E;  3P3C A;  3M85 D;  4OO1 F;  4IZJ A;  5K36 F;  3ZKB A;  2J7K A;  4JI0 I;  4OO1 C;  2WP8 A;  4Z7C A;  5A2Q Q;  2J65 A;  4LF4 I;  1KKH A;  1RR9 A;  4B3T I;  3UHM A;  2JE6 A;  5JEA C;  4X66 I;  4JI5 E;  4DR4 E;  4WUD A;  3HUL A;  1B62 A;  4FN5 A;  4DXL A;  4X62 E;  1FI4 A;  4LFB I;  1OJ4 A;  4DV7 E;  4FW4 A;  4M1K A;  4AQY I;  1Z0G A;  2BR2 A;  4ED4 A;  2Q2E B;  3QT7 A;  1XMQ I;  3PS1 A;  4B3R I;  4OKG A;  4XTJ A;  1XMQ E;  4NXM I;  3L7Z B;  4J3D A;  1YH8 A;  2HHH E;  2WNR A;  4FW5 A;  2UXC I;  1HNZ I;  2HFS A;  4AIM A;  4DV2 E;  2GO3 A;  3QT8 A;  4FW6 A;  3Q6N A;  1Y60 A;  4QNK A;  2UUA I;  2BR2 B;  1ZM3 A;  4X66 E;  2F4V I;  4DR6 E;  3J7A M;  1Z5B A;  4DV3 I;  1MG7 A;  2PNL A;  1HR0 I;  2UU9 E;  1PIE A;  1HR0 E;  1USV A;  4YY3 E;  2BA1 D;  2BA0 D;  2O3Z A;  2PO0 A;  1BKN A;  2HK3 A;  2Z5B B;  1H72 C;  2JEB A;  4HAC B;  4MYU A;  4OZE A;  5DRR A;  2IES A;  3WU5 A;  3PYE A;  1EA6 A;  4LPF A;  3F0N A;  1N33 I;  4NBQ A;  2R3V A;  3J81 Q;  2CZ9 A;  4DR3 E;  4IFD D;  4X65 I;  1Z0E A;  1UDO A;  5L3J A;  3M85 G;  4LF8 I;  2HHH I;  4GKJ E;  4DR2 E;  1FJG E;  5C0X D;  1YHC A;  1N34 E;  3B4T A;  1Z5C A;  2UUC E;  3WU4 A;  1N34 I;  1NHH A;  1MU5 A;  4B3M E;  2Z5B A;  4DR5 E;  4DPY A;  4DV4 E;  1HNX E;  4JG4 A;  4HY1 A;  1K47 A;  2VQE E;  1OYR A;  4IS9 A;  3DD6 A;  4Z7Y A;  4DPU A;  1N0V C;  1Z59 A;  1Y4S A;  2O1T A;  2WW4 A;  4N3O A;  2VQF I;  4DU8 A;  3CDJ A;  4FW9 A;  4JI6 E;  3P06 A;  4MU4 A;  2BM0 A;  2V34 A;  4MQY A;  3PYD A;  1A6F A;  4JI7 E;  4I3H A;  4OO1 B;  4PRV A;  1ZM2 A;  2CG9 A;  5JEA B;  3J80 Q;  4GKK E;  4DR6 I;  2AJ4 A;  4DV7 I;  5C0X C;  1IBM E;  1IBL E;  3PYG A;  4LFB E;  1H73 A;  2C39 B;  3GON A;  4IFD A;  2CGE A;  3CWV A;  1HNZ E;  3ZZU A;  4B3M I;  1U2R A;  5FWK A;  2F1D A;  2X36 A;  3P3G A;  1N36 E;  3JAM Q;  4DR4 I;  2UXC E;  4LF8 E;  4FWG A;  5JEA D;  4DR1 I;  4AQY E;  5IWA E;  2ZBK B;  4MU3 A;  1KIJ A;  2V2Z A;  4LOM A;  4R1F A;  2BA0 G;  3T1Y E;  2E5L E;  3K1J A;  3J7A G;  4JI2 I;  2BM1 A;  1UEK A;  5BR8 I;  5DRP A;  2UXD E;  5K36 C;  4OX9 I;  4JI2 E;  5K36 D;  3H4L A;  5C0X A;  3M6A A;  4LF9 I;  4IFD C;  3ZKD A;  2GO4 A;  2OI2 A;  1D6T A;  3V5R A;  2NN6 E;  4JI5 I;  1WUU A;  4LF4 E;  3T1H E;  2GQ0 A;  2NN6 B;  2DEJ A;  1ZXM A;  2HK2 A;  4AM3 A;  2LJP A;  2Z5E A;  3K85 A;  2UUB I;  1XMO I;  2NN6 F;  2HFU A;  2UUC I;  1Y6Z A;  5K36 A;  2PO1 A;  4JV5 E;  5GMD A;  1S4E A;  4MU1 A;  4DPX A;  2BA1 G;  2V2V A;  4WUB A;  5DRQ A;  4LFA I;  4FWH A;  1Y4U A;  2PNZ A;  4LF6 I;  4MU0 A;  1PKP A;  4FW7 A;  4JI1 I;  1Z5A A;  1XNR I;  1N33 E;  4OX9 E;  4LCG A;  3ZZ0 A;  3OTO E;  3OTO I;  3GCM A;  5LMU E;  4DV1 I;  3NZK A;  1Z0V A;  2VQE I;  2C37 A;  2UUA E;  1Z0C A;  3M7N D;  4DR7 E;  5JEA F;  4LF7 I;  5EL9 A;  1Z0T A;  2UXD I;  4JI8 I;  1R6M A;  3GLL A;  5K36 B;  2XEX A;  4MDT A;  2HKE A;  3T1H I;  2NN6 A;  2F4V E;  4OO1 E;  4JI3 I;  4DUY I;  4URL A;  4WUC A;  2UXB I;  3V2U C;  5JEA E;  3U1Y A;  3LPS A;  2C38 B;  1N0U A;  4JI4 I;  2IER A;  1NHI A;  1Z0B A;  4GKK I;  4LF5 E;  2BV3 A;  4RPF A;  4BA2 B;  1OYP A;  2PO1 B;  1ELO A;  1ZM9 A;  1KTV A;  4B3S E;  4DPW A;  1IBL I;  1QZR A;  1IBK E;  4PRX A;  4DUZ E;  4NXM E;  2JEA B;  5FLX C;  5LL6 R;  4LFC I;  2Z5C B;  3JAM C;  2VQF E;  5GME A;  2PO0 B;  4LCF A;  1XNQ I;  4JI6 I;  1HNX I;  2HKJ A;  4IZK A;  4KQV A;  5IWA I;  2PO2 B;  4LF7 E;  4DV4 I;  5BR8 E;  4GQU A;  5LMU I;  4DV1 E;  4JI1 E;  4DV6 I;  1N32 I;  4JI8 E;  3P3E A;  4B3T E;  4K0K E;  4EMD A;  1P42 A;  5IT9 Q;  4IFD F;  4JI4 E;  2WNR B;  3D4J A;  1S16 A;  4KHP E;  3B82 A;  4JI7 I;  4JI0 E;  2ZM6 E;  4LF5 I;  3ZZT A;  1XMO E;  4X64 E;  4JI3 E;  1H74 A;  1UDQ A;  2ZM6 I;  1E3P A;  2ZIT A;  5C0X B;  4JYA E;  4LFA E;  3P76 A;  4P52 A;  1ZXN A;  2PO2 A;  4FW3 A;  1XNR E;  1IBM I;  2NN6 D;  4HYM A;  2VF3 A;  2AE8 A;  3Q1Q A;  2Z5C A;  1FKA E;  4DV0 E;  3HKM A;  5ELW A;  1EI1 A;  4U3B A;  5EKW A;  1ZM4 A;  1J5E I;  2UUB E;  4BA1 B;  3ZM7 A;  2JEB B;  4LF9 E;  4HAC A;  2A2C A;  4IZK B;  4JV5 I;  1UDN A;  2O1V A;  1N36 I; 
#chains in the Genus database with same CATH homology
 5ELW A;  5DNX A;  4QNJ A;  1RHY A;  4QNK A;  2AE8 A;  5DNL A;  4MU3 A;  4GQU A;  5EL9 A;  4LPF A;  4LOM A;  4MU0 A;  4MU1 A;  2F1D A;  5EKW A;  4MU4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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