4QNKA

The structure of wt a. thaliana igpd2 in complex with mn2+ and phosphate
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
185
structure length
185
Chain Sequence
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
total genus 58
structure length 185
sequence length 185
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2014-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4qnkA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4qnkA02
4MU0A 1RHYA 5EKWA 5ELWA 4QNKA 5DNLA 4MU3A 5DNXA 4MU4A 4MU1A 5EL9A 4QNJA 4LOMA 2AE8A 4LPFA 4GQUA 2F1DA
chains in the Genus database with same CATH superfamily
3H4LA 4JV5I 4IFDC 2UXDE 1XMQE 5C0XD 4JI7I 3PYEA 2GO3A 3M7NG 2IESA 4MU0A 2ZITA 2C38B 3GONA 1MG7A 1B62A 1HNZE 2HHHI 1FJGE 2AE8A 2UUAI 2BR2A 1RHYA 5JEAD 4IFDE 4JI4E 1VI7A 2HKEA 4GKJE 3J81Q 4DR5E 1R6MA 1R6LA 4MQYA 3P3EA 4HYMA 4DR6E 3PYFA 4OZEA 1NZ0A 5DNXA 5BR8E 3L7ZB 2C38A 3T1HI 4IFDF 2X7IA 1Z0WA 3NZKA 2VESA 4X66I 1XMQI 4FWHA 4Z7CA 4LCGA 2PO0B 2VQFI 1FJGI 5EL9A 4OO1F 5DRPA 4JI4I 1J5EE 5K36B 4IS9A 4OO1B 4P52A 4GKJI 4DR5I 1Z0BA 1Y4UA 1HNXE 4LOMA 5C0XC 1EI1A 4X62E 5BR8I 2X36A 4AQYE 4FW5A 4MU3A 1DARA 4B3SI 3ZKBA 4JI1E 2NN6A 3K85A 1IBLE 5JEAC 1Z0TA 5C0XE 2UUBI 2NN6B 3Q6MA 5FLXQ 4ISAA 4AM3A 1J5EI 2Z5EA 4KHPE 3ZZTA 5C0XF 5JEAE 2E1RA 1HNXI 4PU9A 5A2QQ 2VQEI 4KQVA 4U3DA 4JI1I 5IT9C 1HR0E 4P7AA 4DV3E 1S16A 4DUZE 3CDIA 4DPWA 1IBLI 3QT5A 4WUDA 4YHHE 2BM0A 4DPXA 1KTVA 1H7UA 4NXNI 4X65I 1XXEA 5LL6R 1N34E 5LMUE 4OX9E 4KHPI 1Y6ZA 2J65A 3CDJA 2C37A 4LF6E 4YY3I 1A6FA 3OTOI 2Z5BB 3B4TA 2IOPA 1Y4SA 2BA1D 2PO1B 2WP8B 2Z5CA 1HR0I 4DV3I 5DRQA 1UDOA 4OKGA 4LF7E 4LF8E 3J7AM 4YHHI 2CVEA 4JI0I 3K17A 3JAMC 1NHIA 1Y60A 2Q2EB 1FKAE 5LMUI 1WUUA 4JI7E 2UU9E 4NXMI 4LF6I 1ELOA 4IZJA 4BA1A 1B63A 2O1WA 4M1KA 3PS1A 3QT7A 4BA2B 1USUA 3B8HA 4LF7I 1OYSA 2GO4A 1Z0VA 3J80C 3T1HE 4ZVIA 2BA1G 4X66E 5DROA 2UU9I 4DR2E 4WUCA 1N0VC 1IBKI 3LPSA 3F0NA 3CWVA 1PVGA 2VQFE 3HULA 1N32I 2DEJA 2NN6D 4DU7A 3L7ZA 3P06A 4DPYA 1U2RA 2NPFA 4HACB 2UXCE 4DR1I 4GKKE 4B3SE 2IERA 2PO0A 5ELWA 2A2DA 3WU5A 4DV6E 4AIDA 4IFDB 4DR2I 1H74A 4DV5I 4LF5E 3P3GA 4X64E 5K36A 4OO1A 3P3CA 4ED4A 4UT4A 2PNMA 4DR7I 4DR3E 1UDSA 2OI2A 3M6AA 2UUBE 1PIEA 4LFBE 4JI6E 4JYAE 1P42A 2WW4A 3PYDA 2DEIA 4DPTA 3ZM7A 2O3ZA 2HK3A 1Z5BA 1ZM4A 4GQUA 2UXCI 2JEBB 3T1YI 5DRRA 4GKKI 1USVA 2CG9A 1K47A 2VQEE 4MYUA 4DV6I 1Z5CA 4QNKA 4LF5I 2CZ9A 2NN6C 4X64I 5IT9Q 4DV7I 4DR3I 4DV2E 4NXNE 3U1KA 1MX0A 3ZKDA 4LFBI 4X65E 4JI6I 4JYAI 1E3PA 1VISA 1H72C 4PRVA 1FNMA 2EFGA 2NN6E 2V2VA 4YY3E 3KRNA 4LF4I 1FWKA 3OTOE 2V2ZA 5C0XB 5IWAI 2BV3A 5JEAF 4LFAE 4IZJD 4Z7YA 4JI0E 1OYRA 4U3BA 4WUBA 3WU6A 4DV2I 4DPUA 3ZZ0A 1Z0CA 3WU4A 2Z5BA 3V2UC 2O1TA 2BA0D 4USKA 2PO1A 1Z59A 1MU5A 2WP8A 4NXME 3JAMQ 2GS8A 2F4VI 4FW6A 4LF9E 4MU1A 3Q6NA 1H73A 4R1FA 4LFAI 3PRYA 3V5RA 5FLXC 1PKPA 2F1DA 2PO2A 1OYPA 5GMEA 5DNLA 3H1CA 1H7SA 5A2QC 2JE6A 4DV0E 2PNZA 1XMOI 3J80Q 2PO2B 1KVKA 1IBKE 4BA2A 2V34A 2C39B 4FW9A 4LF9I 1HNWE 2R3VA 2JE6B 4B3ME 1NHHA 2PNZB 1UDQA 1N32E 5LMNE 2CGEA 4DXLA 1ZM2A 1N36I 2JEAB 5K36D 3PYGA 4OO1D 1EA6A 3LTOA 4DR1E 3J7AG 2BM1A 1RR9A 1N0UA 4DV4E 4DV0I 1KIJA 4K0KI 4DV5E 2V2QA 1HNWI 1KKHA 1ZXNA 4DR7E 4DUYI 4B3MI 3GCMA 4HACA 4XTJA 5LMNI 4FW7A 2UUCI 3P76A 1E3HA 2JT2A 2UXBI 4IFDA 3T1YE 2VF3A 4JI3I 4DV4I 2PNLA 3PS3A 4MDTA 3B82A 4JI8I 3PS2A 4DV7E 1UEKA 3D4JA 1UDNA 2AJ4A 5K36C 2JEBA 4OO1C 4JI2E 4B3TE 4FW3A 1OJ4A 2BR2B 1HK7A 3UHMA 4LF4E 3WU3A 2E5LE 1XNRE 1XHKA 4JI5E 1IBME 4DR4E 5K36E 4OO1E 2UXDI 5IWAE 1I94E 1Z0EA 4AIMA 4HXZA 2R42A 1HNZI 5EKWA 3J81C 5K36F 2HFUA 4USMA 1Z0GA 3M85D 1FI4A 4JI2I 4JG4A 5C0XA 4B3TI 4FW4A 4DU8A 4DR6I 4NBQA 2F4VE 2WNRA 2E5LI 1XNRI 4JI5I 4HY1A 1IBMI 4DR4I 5JEAA 4FN5A 1FWLA 1D6TA 4N3OA 3ZZUA 1N33E 2WNRB 2NN6F 1I94I 1ZXMA 2HKJA 5JEAB 2J7KA 1ZM9A 1RREA 4FWDA 5FWKA 4B3RE 1XNQE 1XMOE 2ZBKB 1YHCA 4DV1E 2GQ0A 3QT8A 4X62I 4AQYI 4EMDA 4FWGA 2A2CA 1S4EA 2O1VA 3M85G 3DD6A 1N33I 3HJCA 5GMDA 1N36E 4RPFA 2XEXA 1Z5AA 2C39A 1Y5YA 4B3RI 2ZM6E 1XNQI 3HKMA 3Q1QA 4K0KE 4URLA 2V8PA 4DV1I 4IFDD 1YH8A 2HFSA 2IOQA 2JEAA 4DUYE 3GMEA 4LCFA 2C37B 3M7ND 4DUZI 2O1UA 3LNUA 4MYTA 2UUCE 4LFCE 2LJPA 2HK2A 1ZM3A 2BA0G 2Z5CB 2UXBE 3GLLA 4PRXA 4JV5E 4JI3E 4LPFA 3U1YA 1N34I 2ZM6I 4OX9I 4I3HA 1NHJA 4IZKA 1BKNA 2HHHE 4JI8E 2UUAE 4MU4A 4IZKB 4UTGA 4IZJB 4BA1B 3B78A 5L3JA 4LFCI 4LF8I 3K1JA 4QNJA 1QZRA 4J3DA 3QT6A 4LCHA
chains in the Genus database with same CATH topology
4MU0A 1RHYA 5EKWA 5ELWA 4QNKA 5DNLA 4MU3A 5DNXA 4MU4A 4MU1A 5EL9A 4QNJA 4LOMA 2AE8A 4LPFA 4GQUA 2F1DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MU0 A;  1RHY A;  5EKW A;  5ELW A;  4QNK A;  5DNL A;  4MU3 A;  5DNX A;  4MU4 A;  4MU1 A;  5EL9 A;  4QNJ A;  4LOM A;  2AE8 A;  4LPF A;  4GQU A;  2F1D A; 
#chains in the Genus database with same CATH topology
 3H4L A;  4JV5 I;  4IFD C;  2UXD E;  1XMQ E;  5C0X D;  4JI7 I;  3PYE A;  2GO3 A;  3M7N G;  2IES A;  4MU0 A;  2ZIT A;  2C38 B;  3GON A;  1MG7 A;  1B62 A;  1HNZ E;  2HHH I;  1FJG E;  2AE8 A;  2UUA I;  2BR2 A;  1RHY A;  5JEA D;  4IFD E;  4JI4 E;  1VI7 A;  2HKE A;  4GKJ E;  3J81 Q;  4DR5 E;  1R6M A;  1R6L A;  4MQY A;  3P3E A;  4HYM A;  4DR6 E;  3PYF A;  4OZE A;  1NZ0 A;  5DNX A;  5BR8 E;  3L7Z B;  2C38 A;  3T1H I;  4IFD F;  2X7I A;  1Z0W A;  3NZK A;  2VES A;  4X66 I;  1XMQ I;  4FWH A;  4Z7C A;  4LCG A;  2PO0 B;  2VQF I;  1FJG I;  5EL9 A;  4OO1 F;  5DRP A;  4JI4 I;  1J5E E;  5K36 B;  4IS9 A;  4OO1 B;  4P52 A;  4GKJ I;  4DR5 I;  1Z0B A;  1Y4U A;  1HNX E;  4LOM A;  5C0X C;  1EI1 A;  4X62 E;  5BR8 I;  2X36 A;  4AQY E;  4FW5 A;  4MU3 A;  1DAR A;  4B3S I;  3ZKB A;  4JI1 E;  2NN6 A;  3K85 A;  1IBL E;  5JEA C;  1Z0T A;  5C0X E;  2UUB I;  2NN6 B;  3Q6M A;  5FLX Q;  4ISA A;  4AM3 A;  1J5E I;  2Z5E A;  4KHP E;  3ZZT A;  5C0X F;  5JEA E;  2E1R A;  1HNX I;  4PU9 A;  5A2Q Q;  2VQE I;  4KQV A;  4U3D A;  4JI1 I;  5IT9 C;  1HR0 E;  4P7A A;  4DV3 E;  1S16 A;  4DUZ E;  3CDI A;  4DPW A;  1IBL I;  3QT5 A;  4WUD A;  4YHH E;  2BM0 A;  4DPX A;  1KTV A;  1H7U A;  4NXN I;  4X65 I;  1XXE A;  5LL6 R;  1N34 E;  5LMU E;  4OX9 E;  4KHP I;  1Y6Z A;  2J65 A;  3CDJ A;  2C37 A;  4LF6 E;  4YY3 I;  1A6F A;  3OTO I;  2Z5B B;  3B4T A;  2IOP A;  1Y4S A;  2BA1 D;  2PO1 B;  2WP8 B;  2Z5C A;  1HR0 I;  4DV3 I;  5DRQ A;  1UDO A;  4OKG A;  4LF7 E;  4LF8 E;  3J7A M;  4YHH I;  2CVE A;  4JI0 I;  3K17 A;  3JAM C;  1NHI A;  1Y60 A;  2Q2E B;  1FKA E;  5LMU I;  1WUU A;  4JI7 E;  2UU9 E;  4NXM I;  4LF6 I;  1ELO A;  4IZJ A;  4BA1 A;  1B63 A;  2O1W A;  4M1K A;  3PS1 A;  3QT7 A;  4BA2 B;  1USU A;  3B8H A;  4LF7 I;  1OYS A;  2GO4 A;  1Z0V A;  3J80 C;  3T1H E;  4ZVI A;  2BA1 G;  4X66 E;  5DRO A;  2UU9 I;  4DR2 E;  4WUC A;  1N0V C;  1IBK I;  3LPS A;  3F0N A;  3CWV A;  1PVG A;  2VQF E;  3HUL A;  1N32 I;  2DEJ A;  2NN6 D;  4DU7 A;  3L7Z A;  3P06 A;  4DPY A;  1U2R A;  2NPF A;  4HAC B;  2UXC E;  4DR1 I;  4GKK E;  4B3S E;  2IER A;  2PO0 A;  5ELW A;  2A2D A;  3WU5 A;  4DV6 E;  4AID A;  4IFD B;  4DR2 I;  1H74 A;  4DV5 I;  4LF5 E;  3P3G A;  4X64 E;  5K36 A;  4OO1 A;  3P3C A;  4ED4 A;  4UT4 A;  2PNM A;  4DR7 I;  4DR3 E;  1UDS A;  2OI2 A;  3M6A A;  2UUB E;  1PIE A;  4LFB E;  4JI6 E;  4JYA E;  1P42 A;  2WW4 A;  3PYD A;  2DEI A;  4DPT A;  3ZM7 A;  2O3Z A;  2HK3 A;  1Z5B A;  1ZM4 A;  4GQU A;  2UXC I;  2JEB B;  3T1Y I;  5DRR A;  4GKK I;  1USV A;  2CG9 A;  1K47 A;  2VQE E;  4MYU A;  4DV6 I;  1Z5C A;  4QNK A;  4LF5 I;  2CZ9 A;  2NN6 C;  4X64 I;  5IT9 Q;  4DV7 I;  4DR3 I;  4DV2 E;  4NXN E;  3U1K A;  1MX0 A;  3ZKD A;  4LFB I;  4X65 E;  4JI6 I;  4JYA I;  1E3P A;  1VIS A;  1H72 C;  4PRV A;  1FNM A;  2EFG A;  2NN6 E;  2V2V A;  4YY3 E;  3KRN A;  4LF4 I;  1FWK A;  3OTO E;  2V2Z A;  5C0X B;  5IWA I;  2BV3 A;  5JEA F;  4LFA E;  4IZJ D;  4Z7Y A;  4JI0 E;  1OYR A;  4U3B A;  4WUB A;  3WU6 A;  4DV2 I;  4DPU A;  3ZZ0 A;  1Z0C A;  3WU4 A;  2Z5B A;  3V2U C;  2O1T A;  2BA0 D;  4USK A;  2PO1 A;  1Z59 A;  1MU5 A;  2WP8 A;  4NXM E;  3JAM Q;  2GS8 A;  2F4V I;  4FW6 A;  4LF9 E;  4MU1 A;  3Q6N A;  1H73 A;  4R1F A;  4LFA I;  3PRY A;  3V5R A;  5FLX C;  1PKP A;  2F1D A;  2PO2 A;  1OYP A;  5GME A;  5DNL A;  3H1C A;  1H7S A;  5A2Q C;  2JE6 A;  4DV0 E;  2PNZ A;  1XMO I;  3J80 Q;  2PO2 B;  1KVK A;  1IBK E;  4BA2 A;  2V34 A;  2C39 B;  4FW9 A;  4LF9 I;  1HNW E;  2R3V A;  2JE6 B;  4B3M E;  1NHH A;  2PNZ B;  1UDQ A;  1N32 E;  5LMN E;  2CGE A;  4DXL A;  1ZM2 A;  1N36 I;  2JEA B;  5K36 D;  3PYG A;  4OO1 D;  1EA6 A;  3LTO A;  4DR1 E;  3J7A G;  2BM1 A;  1RR9 A;  1N0U A;  4DV4 E;  4DV0 I;  1KIJ A;  4K0K I;  4DV5 E;  2V2Q A;  1HNW I;  1KKH A;  1ZXN A;  4DR7 E;  4DUY I;  4B3M I;  3GCM A;  4HAC A;  4XTJ A;  5LMN I;  4FW7 A;  2UUC I;  3P76 A;  1E3H A;  2JT2 A;  2UXB I;  4IFD A;  3T1Y E;  2VF3 A;  4JI3 I;  4DV4 I;  2PNL A;  3PS3 A;  4MDT A;  3B82 A;  4JI8 I;  3PS2 A;  4DV7 E;  1UEK A;  3D4J A;  1UDN A;  2AJ4 A;  5K36 C;  2JEB A;  4OO1 C;  4JI2 E;  4B3T E;  4FW3 A;  1OJ4 A;  2BR2 B;  1HK7 A;  3UHM A;  4LF4 E;  3WU3 A;  2E5L E;  1XNR E;  1XHK A;  4JI5 E;  1IBM E;  4DR4 E;  5K36 E;  4OO1 E;  2UXD I;  5IWA E;  1I94 E;  1Z0E A;  4AIM A;  4HXZ A;  2R42 A;  1HNZ I;  5EKW A;  3J81 C;  5K36 F;  2HFU A;  4USM A;  1Z0G A;  3M85 D;  1FI4 A;  4JI2 I;  4JG4 A;  5C0X A;  4B3T I;  4FW4 A;  4DU8 A;  4DR6 I;  4NBQ A;  2F4V E;  2WNR A;  2E5L I;  1XNR I;  4JI5 I;  4HY1 A;  1IBM I;  4DR4 I;  5JEA A;  4FN5 A;  1FWL A;  1D6T A;  4N3O A;  3ZZU A;  1N33 E;  2WNR B;  2NN6 F;  1I94 I;  1ZXM A;  2HKJ A;  5JEA B;  2J7K A;  1ZM9 A;  1RRE A;  4FWD A;  5FWK A;  4B3R E;  1XNQ E;  1XMO E;  2ZBK B;  1YHC A;  4DV1 E;  2GQ0 A;  3QT8 A;  4X62 I;  4AQY I;  4EMD A;  4FWG A;  2A2C A;  1S4E A;  2O1V A;  3M85 G;  3DD6 A;  1N33 I;  3HJC A;  5GMD A;  1N36 E;  4RPF A;  2XEX A;  1Z5A A;  2C39 A;  1Y5Y A;  4B3R I;  2ZM6 E;  1XNQ I;  3HKM A;  3Q1Q A;  4K0K E;  4URL A;  2V8P A;  4DV1 I;  4IFD D;  1YH8 A;  2HFS A;  2IOQ A;  2JEA A;  4DUY E;  3GME A;  4LCF A;  2C37 B;  3M7N D;  4DUZ I;  2O1U A;  3LNU A;  4MYT A;  2UUC E;  4LFC E;  2LJP A;  2HK2 A;  1ZM3 A;  2BA0 G;  2Z5C B;  2UXB E;  3GLL A;  4PRX A;  4JV5 E;  4JI3 E;  4LPF A;  3U1Y A;  1N34 I;  2ZM6 I;  4OX9 I;  4I3H A;  1NHJ A;  4IZK A;  1BKN A;  2HHH E;  4JI8 E;  2UUA E;  4MU4 A;  4IZK B;  4UTG A;  4IZJ B;  4BA1 B;  3B78 A;  5L3J A;  4LFC I;  4LF8 I;  3K1J A;  4QNJ A;  1QZR A;  4J3D A;  3QT6 A;  4LCH A; 
#chains in the Genus database with same CATH homology
 4MU0 A;  1RHY A;  5EKW A;  5ELW A;  4QNK A;  5DNL A;  4MU3 A;  5DNX A;  4MU4 A;  4MU1 A;  5EL9 A;  4QNJ A;  4LOM A;  2AE8 A;  4LPF A;  4GQU A;  2F1D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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