4QNKA

The structure of wt a. thaliana igpd2 in complex with mn2+ and phosphate
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
185
structure length
185
Chain Sequence
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
total genus 58
structure length 185
sequence length 185
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2014-06-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4qnkA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4qnkA02
5EKWA 2F1DA 4MU4A 4QNJA 5ELWA 1RHYA 5EL9A 4MU1A 4QNKA 4LOMA 5DNXA 4MU3A 2AE8A 4GQUA 4MU0A 4LPFA 5DNLA
chains in the Genus database with same CATH superfamily
4N3OA 3V5RA 1J5EE 4GKKE 4X64I 2VESA 5GMEA 1XNRI 1Z0GA 1N34E 4WUDA 2NN6F 4M1KA 4X65I 4JYAI 2O3ZA 5FLXQ 2JEAA 3J81Q 2C37A 3WU5A 4MYUA 4OZEA 4DPXA 4IFDF 4LF9E 4IFDE 2WP8B 4NXMI 4OX9I 1NHIA 4FW6A 1HNXI 4USMA 3M6AA 1Z5AA 1Z0VA 4MU4A 3CDJA 2PNMA 4MU3A 4LF8I 2Z5BB 2UXCI 3B78A 4U3BA 3D4JA 1MU5A 4DV2E 2WNRA 5C0XE 4GQUA 2VQFI 1HR0E 5FWKA 3M7NG 4ED4A 2HK3A 2J65A 2VF3A 4LCFA 4MYTA 4DR5I 2X36A 2CG9A 2HFSA 2CVEA 5A2QQ 4YY3I 4DV4E 3GLLA 4WUCA 4PRXA 2HHHE 4QNJA 2V2QA 1RHYA 4UT4A 4DUYI 3ZKBA 3DD6A 2NN6C 2OI2A 1S4EA 1HNZE 4JI6I 5IT9Q 2PNLA 2UUAI 4OKGA 2LJPA 4IFDC 2HKJA 4ISAA 4LCGA 4B3SI 3GMEA 4JI0I 3M7ND 4JI4E 1RR9A 2IOPA 4NXNI 2UXDE 5A2QC 4HXZA 4X62E 1RREA 1HNWE 5K36B 1IBLI 1N36I 3OTOI 3PS1A 1PKPA 3JAMQ 4JI3E 4JI8E 4Z7CA 1QZRA 5C0XC 1Z5BA 2UXBE 1B62A 1N33E 4ZVIA 4FW7A 1ZM4A 3PYGA 2UUCI 1ZM9A 5IT9C 1XNQI 2PO0A 4DV7I 4HACB 3LTOA 2Z5BA 1Z59A 4LF7E 1N0UA 1H7UA 2NN6A 3B82A 5LL6R 4B3TE 4DV0E 2CZ9A 4DR4I 2NN6D 1NZ0A 3PS3A 3JAMC 4PRVA 1EI1A 4HYMA 3CWVA 3V2UC 2Z5CA 4K0KI 4DR6I 1ZXNA 2GS8A 4JI5E 3T1HI 3T1YE 4OO1B 2BM1A 2F4VI 1IBKE 4DR1E 5BR8I 4DXLA 1EA6A 1FWLA 2BR2B 2BA0G 2PO2B 2ZITA 2JE6B 4DUZI 2A2DA 4JV5I 1Y4UA 4LFBE 3PYEA 4X66E 1U2RA 4BA2B 5IWAE 1Y4SA 1YHCA 4LF5E 5K36D 3HULA 3GCMA 2UU9I 2NPFA 4LF4I 2NN6E 5LMNI 1KTVA 1R6LA 1ZM2A 1UEKA 1NHHA 1J5EI 4GKKI 2BA0D 4DR3E 4DV6E 4GKJE 1XNRE 1N34I 4DPTA 4QNKA 4Z7YA 4LFCE 5LMUE 4LF9I 4NXME 4FW3A 1HNXE 1FI4A 1PIEA 2PO1B 4FW9A 4JI7E 5FLXC 3J81C 1H7SA 4EMDA 4FWHA 2PNZA 4DV5E 4OO1A 2AJ4A 4KHPE 3NZKA 1HR0I 4AQYE 2BM0A 3U1KA 2JEBB 1FNMA 4OO1D 1XMOE 2ZM6I 4LFAI 5K36F 3KRNA 2PO2A 2JE6A 5K36E 1XMQE 3J80Q 4YY3E 4DV4I 4B3ME 3P3CA 4LF6I 2O1TA 3P76A 3ZKDA 4IZJB 4FWDA 2C38B 4MU1A 4JI1E 4DUYE 2XEXA 2Q2EB 2E5LI 4DPWA 2R42A 1MG7A 2HK2A 1Z0EA 4DR2I 2J7KA 1OYPA 1HNZI 4JI6E 2UUAE 4FN5A 5GMDA 3QT8A 1Z0CA 5C0XB 1FWKA 1HK7A 1Y6ZA 4JI0E 1VISA 3K17A 2IERA 1OJ4A 2WP8A 2UXDI 2GO4A 4X62I 1OYRA 1HNWI 5EL9A 1E3HA 4FW5A 2GO3A 3M85G 4JI8I 3UHMA 3H4LA 4HY1A 1ZXMA 1I94I 4OO1F 2C39B 3U1YA 2UUCE 4OO1E 5DRPA 4DV3I 4PU9A 2PO1A 5K36C 1Y60A 4DV7E 4DR7I 4MDTA 4JI2I 4LF7I 1OYSA 1H74A 5JEAB 1FJGE 2JEAB 2C37B 3ZZ0A 1USUA 4DV0I 2BA1G 4DR4E 2JEBA 3QT7A 4MQYA 3WU3A 1UDNA 3WU6A 3M85D 1IBMI 2F1DA 4JG4A 1Z0TA 2UUBI 4YHHE 1N32E 3LNUA 4DV1I 3B4TA 4B3RE 2DEJA 3T1HE 2ZBKB 4IZJA 3T1YI 2WNRB 1FKAE 3J7AM 2F4VE 4IZJD 1IBKI 4DR1I 4DU7A 2WW4A 5K36A 2BV3A 2BA1D 5DNXA 2VQEE 4R1FA 5L3JA 1Y5YA 4IZKB 1Z0WA 4OO1C 3HKMA 4JV5E 5DRRA 2A2CA 3L7ZB 2V34A 4X66I 3LPSA 2JT2A 2EFGA 5IWAI 4X64E 4KQVA 4HACA 4LF5I 1ELOA 2O1WA 4X65E 4JYAE 4WUBA 3PS2A 1DARA 3ZM7A 1D6TA 1Z0BA 4DU8A 4DR3I 4GKJI 4DV6I 4URLA 4OX9E 1H73A 4RPFA 5JEAA 2V8PA 2HKEA 4LFCI 5LMUI 1KIJA 2IESA 4LF8E 2UXCE 5JEAD 4P7AA 4DV2I 3P06A 2VQFE 2DEIA 3QT6A 4JI7I 2PO0B 4LOMA 2BR2A 3H1CA 3Q1QA 4MU0A 4DR5E 1B63A 5DNLA 2NN6B 4DV5I 5C0XF 4KHPI 4BA1B 4AQYI 4IFDB 1H72C 3K85A 5EKWA 1XMOI 2HHHI 2ZM6E 1MX0A 4LFAE 1XXEA 4DPUA 4BA2A 2Z5CB 3Q6NA 1XMQI 4IZKA 4AIMA 4B3MI 4FWGA 4LF6E 1USVA 2V2VA 1WUUA 4DPYA 3L7ZA 1YH8A 4JI1I 2V2ZA 4B3SE 2CGEA 4IS9A 2E5LE 4JI4I 4DR2E 3WU4A 1K47A 3J80C 4NXNE 5JEAF 3PYFA 1IBLE 1N36E 3OTOE 5JEAE 4JI3I 1NHJA 2UXBI 2O1UA 4P52A 5DROA 1N33I 4FW4A 2IOQA 3J7AG 3PYDA 2O1VA 1P42A 1S16A 4J3DA 1XNQE 3F0NA 1KVKA 1KKHA 1I94E 3Q6MA 4B3TI 4DV3E 2HFUA 4DR7E 4XTJA 4JI2E 3P3EA 1FJGI 4LCHA 4BA1A 4K0KE 4DR6E 4JI5I 2E1RA 1UDQA 4IFDA 3ZZUA 2C38A 1Z5CA 3P3GA 1IBME 3QT5A 4IFDD 4YHHI 2UUBE 1N32I 2AE8A 4NBQA 5JEAC 1VI7A 5BR8E 4DV1E 2R3VA 4U3DA 4B3RI 3B8HA 2GQ0A 3CDIA 3HJCA 2PNZB 3K1JA 3GONA 1ZM3A 5C0XA 1XHKA 1BKNA 4DUZE 1PVGA 1R6MA 4USKA 5C0XD 4UTGA 4LFBI 3ZZTA 4LPFA 2Z5EA 4AIDA 3PRYA 1N0VC 2VQEI 5ELWA 1E3PA 2X7IA 1A6FA 1UDOA 5DRQA 4I3HA 2UU9E 4LF4E 2C39A 1UDSA 5LMNE 4AM3A
chains in the Genus database with same CATH topology
5EKWA 2F1DA 4MU4A 4QNJA 5ELWA 1RHYA 5EL9A 4MU1A 4QNKA 4LOMA 5DNXA 4MU3A 2AE8A 4GQUA 4MU0A 4LPFA 5DNLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EKW A;  2F1D A;  4MU4 A;  4QNJ A;  5ELW A;  1RHY A;  5EL9 A;  4MU1 A;  4QNK A;  4LOM A;  5DNX A;  4MU3 A;  2AE8 A;  4GQU A;  4MU0 A;  4LPF A;  5DNL A; 
#chains in the Genus database with same CATH topology
 4N3O A;  3V5R A;  1J5E E;  4GKK E;  4X64 I;  2VES A;  5GME A;  1XNR I;  1Z0G A;  1N34 E;  4WUD A;  2NN6 F;  4M1K A;  4X65 I;  4JYA I;  2O3Z A;  5FLX Q;  2JEA A;  3J81 Q;  2C37 A;  3WU5 A;  4MYU A;  4OZE A;  4DPX A;  4IFD F;  4LF9 E;  4IFD E;  2WP8 B;  4NXM I;  4OX9 I;  1NHI A;  4FW6 A;  1HNX I;  4USM A;  3M6A A;  1Z5A A;  1Z0V A;  4MU4 A;  3CDJ A;  2PNM A;  4MU3 A;  4LF8 I;  2Z5B B;  2UXC I;  3B78 A;  4U3B A;  3D4J A;  1MU5 A;  4DV2 E;  2WNR A;  5C0X E;  4GQU A;  2VQF I;  1HR0 E;  5FWK A;  3M7N G;  4ED4 A;  2HK3 A;  2J65 A;  2VF3 A;  4LCF A;  4MYT A;  4DR5 I;  2X36 A;  2CG9 A;  2HFS A;  2CVE A;  5A2Q Q;  4YY3 I;  4DV4 E;  3GLL A;  4WUC A;  4PRX A;  2HHH E;  4QNJ A;  2V2Q A;  1RHY A;  4UT4 A;  4DUY I;  3ZKB A;  3DD6 A;  2NN6 C;  2OI2 A;  1S4E A;  1HNZ E;  4JI6 I;  5IT9 Q;  2PNL A;  2UUA I;  4OKG A;  2LJP A;  4IFD C;  2HKJ A;  4ISA A;  4LCG A;  4B3S I;  3GME A;  4JI0 I;  3M7N D;  4JI4 E;  1RR9 A;  2IOP A;  4NXN I;  2UXD E;  5A2Q C;  4HXZ A;  4X62 E;  1RRE A;  1HNW E;  5K36 B;  1IBL I;  1N36 I;  3OTO I;  3PS1 A;  1PKP A;  3JAM Q;  4JI3 E;  4JI8 E;  4Z7C A;  1QZR A;  5C0X C;  1Z5B A;  2UXB E;  1B62 A;  1N33 E;  4ZVI A;  4FW7 A;  1ZM4 A;  3PYG A;  2UUC I;  1ZM9 A;  5IT9 C;  1XNQ I;  2PO0 A;  4DV7 I;  4HAC B;  3LTO A;  2Z5B A;  1Z59 A;  4LF7 E;  1N0U A;  1H7U A;  2NN6 A;  3B82 A;  5LL6 R;  4B3T E;  4DV0 E;  2CZ9 A;  4DR4 I;  2NN6 D;  1NZ0 A;  3PS3 A;  3JAM C;  4PRV A;  1EI1 A;  4HYM A;  3CWV A;  3V2U C;  2Z5C A;  4K0K I;  4DR6 I;  1ZXN A;  2GS8 A;  4JI5 E;  3T1H I;  3T1Y E;  4OO1 B;  2BM1 A;  2F4V I;  1IBK E;  4DR1 E;  5BR8 I;  4DXL A;  1EA6 A;  1FWL A;  2BR2 B;  2BA0 G;  2PO2 B;  2ZIT A;  2JE6 B;  4DUZ I;  2A2D A;  4JV5 I;  1Y4U A;  4LFB E;  3PYE A;  4X66 E;  1U2R A;  4BA2 B;  5IWA E;  1Y4S A;  1YHC A;  4LF5 E;  5K36 D;  3HUL A;  3GCM A;  2UU9 I;  2NPF A;  4LF4 I;  2NN6 E;  5LMN I;  1KTV A;  1R6L A;  1ZM2 A;  1UEK A;  1NHH A;  1J5E I;  4GKK I;  2BA0 D;  4DR3 E;  4DV6 E;  4GKJ E;  1XNR E;  1N34 I;  4DPT A;  4QNK A;  4Z7Y A;  4LFC E;  5LMU E;  4LF9 I;  4NXM E;  4FW3 A;  1HNX E;  1FI4 A;  1PIE A;  2PO1 B;  4FW9 A;  4JI7 E;  5FLX C;  3J81 C;  1H7S A;  4EMD A;  4FWH A;  2PNZ A;  4DV5 E;  4OO1 A;  2AJ4 A;  4KHP E;  3NZK A;  1HR0 I;  4AQY E;  2BM0 A;  3U1K A;  2JEB B;  1FNM A;  4OO1 D;  1XMO E;  2ZM6 I;  4LFA I;  5K36 F;  3KRN A;  2PO2 A;  2JE6 A;  5K36 E;  1XMQ E;  3J80 Q;  4YY3 E;  4DV4 I;  4B3M E;  3P3C A;  4LF6 I;  2O1T A;  3P76 A;  3ZKD A;  4IZJ B;  4FWD A;  2C38 B;  4MU1 A;  4JI1 E;  4DUY E;  2XEX A;  2Q2E B;  2E5L I;  4DPW A;  2R42 A;  1MG7 A;  2HK2 A;  1Z0E A;  4DR2 I;  2J7K A;  1OYP A;  1HNZ I;  4JI6 E;  2UUA E;  4FN5 A;  5GMD A;  3QT8 A;  1Z0C A;  5C0X B;  1FWK A;  1HK7 A;  1Y6Z A;  4JI0 E;  1VIS A;  3K17 A;  2IER A;  1OJ4 A;  2WP8 A;  2UXD I;  2GO4 A;  4X62 I;  1OYR A;  1HNW I;  5EL9 A;  1E3H A;  4FW5 A;  2GO3 A;  3M85 G;  4JI8 I;  3UHM A;  3H4L A;  4HY1 A;  1ZXM A;  1I94 I;  4OO1 F;  2C39 B;  3U1Y A;  2UUC E;  4OO1 E;  5DRP A;  4DV3 I;  4PU9 A;  2PO1 A;  5K36 C;  1Y60 A;  4DV7 E;  4DR7 I;  4MDT A;  4JI2 I;  4LF7 I;  1OYS A;  1H74 A;  5JEA B;  1FJG E;  2JEA B;  2C37 B;  3ZZ0 A;  1USU A;  4DV0 I;  2BA1 G;  4DR4 E;  2JEB A;  3QT7 A;  4MQY A;  3WU3 A;  1UDN A;  3WU6 A;  3M85 D;  1IBM I;  2F1D A;  4JG4 A;  1Z0T A;  2UUB I;  4YHH E;  1N32 E;  3LNU A;  4DV1 I;  3B4T A;  4B3R E;  2DEJ A;  3T1H E;  2ZBK B;  4IZJ A;  3T1Y I;  2WNR B;  1FKA E;  3J7A M;  2F4V E;  4IZJ D;  1IBK I;  4DR1 I;  4DU7 A;  2WW4 A;  5K36 A;  2BV3 A;  2BA1 D;  5DNX A;  2VQE E;  4R1F A;  5L3J A;  1Y5Y A;  4IZK B;  1Z0W A;  4OO1 C;  3HKM A;  4JV5 E;  5DRR A;  2A2C A;  3L7Z B;  2V34 A;  4X66 I;  3LPS A;  2JT2 A;  2EFG A;  5IWA I;  4X64 E;  4KQV A;  4HAC A;  4LF5 I;  1ELO A;  2O1W A;  4X65 E;  4JYA E;  4WUB A;  3PS2 A;  1DAR A;  3ZM7 A;  1D6T A;  1Z0B A;  4DU8 A;  4DR3 I;  4GKJ I;  4DV6 I;  4URL A;  4OX9 E;  1H73 A;  4RPF A;  5JEA A;  2V8P A;  2HKE A;  4LFC I;  5LMU I;  1KIJ A;  2IES A;  4LF8 E;  2UXC E;  5JEA D;  4P7A A;  4DV2 I;  3P06 A;  2VQF E;  2DEI A;  3QT6 A;  4JI7 I;  2PO0 B;  4LOM A;  2BR2 A;  3H1C A;  3Q1Q A;  4MU0 A;  4DR5 E;  1B63 A;  5DNL A;  2NN6 B;  4DV5 I;  5C0X F;  4KHP I;  4BA1 B;  4AQY I;  4IFD B;  1H72 C;  3K85 A;  5EKW A;  1XMO I;  2HHH I;  2ZM6 E;  1MX0 A;  4LFA E;  1XXE A;  4DPU A;  4BA2 A;  2Z5C B;  3Q6N A;  1XMQ I;  4IZK A;  4AIM A;  4B3M I;  4FWG A;  4LF6 E;  1USV A;  2V2V A;  1WUU A;  4DPY A;  3L7Z A;  1YH8 A;  4JI1 I;  2V2Z A;  4B3S E;  2CGE A;  4IS9 A;  2E5L E;  4JI4 I;  4DR2 E;  3WU4 A;  1K47 A;  3J80 C;  4NXN E;  5JEA F;  3PYF A;  1IBL E;  1N36 E;  3OTO E;  5JEA E;  4JI3 I;  1NHJ A;  2UXB I;  2O1U A;  4P52 A;  5DRO A;  1N33 I;  4FW4 A;  2IOQ A;  3J7A G;  3PYD A;  2O1V A;  1P42 A;  1S16 A;  4J3D A;  1XNQ E;  3F0N A;  1KVK A;  1KKH A;  1I94 E;  3Q6M A;  4B3T I;  4DV3 E;  2HFU A;  4DR7 E;  4XTJ A;  4JI2 E;  3P3E A;  1FJG I;  4LCH A;  4BA1 A;  4K0K E;  4DR6 E;  4JI5 I;  2E1R A;  1UDQ A;  4IFD A;  3ZZU A;  2C38 A;  1Z5C A;  3P3G A;  1IBM E;  3QT5 A;  4IFD D;  4YHH I;  2UUB E;  1N32 I;  2AE8 A;  4NBQ A;  5JEA C;  1VI7 A;  5BR8 E;  4DV1 E;  2R3V A;  4U3D A;  4B3R I;  3B8H A;  2GQ0 A;  3CDI A;  3HJC A;  2PNZ B;  3K1J A;  3GON A;  1ZM3 A;  5C0X A;  1XHK A;  1BKN A;  4DUZ E;  1PVG A;  1R6M A;  4USK A;  5C0X D;  4UTG A;  4LFB I;  3ZZT A;  4LPF A;  2Z5E A;  4AID A;  3PRY A;  1N0V C;  2VQE I;  5ELW A;  1E3P A;  2X7I A;  1A6F A;  1UDO A;  5DRQ A;  4I3H A;  2UU9 E;  4LF4 E;  2C39 A;  1UDS A;  5LMN E;  4AM3 A; 
#chains in the Genus database with same CATH homology
 5EKW A;  2F1D A;  4MU4 A;  4QNJ A;  5ELW A;  1RHY A;  5EL9 A;  4MU1 A;  4QNK A;  4LOM A;  5DNX A;  4MU3 A;  2AE8 A;  4GQU A;  4MU0 A;  4LPF A;  5DNL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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