4MU4A

The form b structure of an e21q catalytic mutant of a. thaliana igpd2 in complex with mn2+ and its substrate, 2r3s-igp, to 1.41 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
199
structure length
199
Chain Sequence
SARIGEVKRETKQTNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRGGTIPSSKGVLSRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
total genus 63
structure length 199
sequence length 199
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu4A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu4A02
4QNJA 4MU3A 4GQUA 4MU0A 4LPFA 4MU1A 2AE8A 4QNKA 5ELWA 5EKWA 2F1DA 4LOMA 1RHYA 5DNXA 5DNLA 5EL9A 4MU4A
chains in the Genus database with same CATH superfamily
1NZ0A 5ELWA 1N36E 2PNLA 4DPWA 1J5EE 4JI0E 4DXLA 2HFUA 2VQEE 4OO1E 1Y4UA 4LF6I 4RPFA 4DR6E 4DR7E 1N0UA 4DV5I 1PIEA 4DPTA 4FWGA 4DV6E 4FW6A 4LFAI 5JEAD 1RHYA 2V2QA 3CDIA 2BA0G 2IERA 4X64E 4BA2B 1PVGA 3K85A 3J80C 1N34E 4DR4E 4BA1A 4MQYA 3M7ND 2ZM6I 3M7NG 4QNJA 4JI3I 3V5RA 4M1KA 1H72C 4PRVA 1Z0GA 4LFCI 4PU9A 1S16A 4DR1E 3LPSA 1ZXNA 2WP8A 5JEAA 4Z7YA 5DNXA 4JI4E 1OJ4A 2BM1A 2NN6E 4GQUA 4MU0A 1MU5A 2V8PA 2AE8A 5LMNI 4DV0I 3T1HI 2CVEA 4JI8I 2NN6B 2BA1G 1Z5BA 2IESA 4DR2E 4QNKA 5IWAI 1IBME 3HULA 1KKHA 2XEXA 4R1FA 5BR8E 1HR0I 4HACB 1OYSA 5IT9Q 1A6FA 3WU5A 1N36I 1DARA 2LJPA 1BKNA 4X66E 5EL9A 2UXCI 4DUYI 4DR7I 2WNRA 3DD6A 2JEBB 4OX9I 1NHHA 1XMOI 1OYRA 3QT6A 1HNWE 2UUAI 4FW5A 4MU3A 2J7KA 1YHCA 2BM0A 1USVA 4DUZE 2JEBA 4B3RI 4OO1C 4LF8E 4DPYA 4WUDA 3Q1QA 4JV5I 2Z5BA 4JI1I 4MYUA 2PO1A 1HNXI 1UDQA 3P3GA 4LFCE 4B3ME 4URLA 3K1JA 1K47A 2HK2A 3JAMQ 4LF4E 2PO1B 2NN6D 4IFDC 3B78A 5FLXQ 1XMQE 1XNQI 3GLLA 5DRRA 3L7ZB 2Z5CA 1ZM4A 4JI8E 2CG9A 4DU7A 2C39A 4DR2I 1N32I 4IS9A 1Y4SA 3ZKDA 4FWDA 2WW4A 2PO0A 3Q6NA 2O1VA 4KHPI 2WP8B 5GMDA 1FJGE 1Y60A 1IBKE 5BR8I 1HK7A 1Y5YA 2PO0B 4DR5I 2GO3A 4AIDA 4WUCA 2J65A 4B3TE 4X66I 4GKJE 4LCGA 2UXCE 1Z0BA 3F0NA 4GKKI 1VI7A 4WUBA 4FW9A 2PO2B 2Q2EB 1N33I 1N0VC 2UU9E 3L7ZA 1HNWI 2C38A 3V2UC 4IFDD 5DROA 1Z0CA 4DUZI 2F4VI 4BA2A 2PO2A 3PRYA 4LF8I 1XNRE 1E3PA 4DV3I 4JV5E 5FLXC 4JI1E 4JI5I 1HNXE 4I3HA 4USMA 2HHHE 3UHMA 3KRNA 2O1WA 5DRPA 4LF4I 2NN6F 5K36E 1EI1A 1XNQE 2BR2B 4OO1A 4LF7E 2O1UA 4IFDE 5C0XA 1J5EI 3T1YE 4HY1A 1NHIA 4PRXA 4LOMA 4LCFA 4LF6E 1N32E 3U1KA 4MDTA 2V2ZA 5C0XB 4JI6E 1P42A 4KHPE 3WU4A 2A2CA 4YY3E 4JI2I 4AQYI 2Z5CB 4DR4I 4DR3E 1EA6A 2BA1D 5K36D 4DR5E 2UUCE 5C0XC 3H4LA 2EFGA 4IZJD 4B3TI 1KTVA 4U3DA 2A2DA 4YHHE 4OKGA 1D6TA 4P52A 1FI4A 4FN5A 3PYGA 2IOQA 1OYPA 2PNMA 1MG7A 2VESA 3PS3A 4JI4I 2F4VE 5LMNE 4ED4A 1XNRI 1ZM9A 3LTOA 4JI5E 2AJ4A 1NHJA 4NXMI 2CZ9A 3M6AA 3OTOE 2JE6A 4J3DA 3PYEA 5K36F 2BR2A 5DNLA 4DV2I 4OO1B 2C37A 2C38B 3U1YA 4LF9E 3K17A 4ZVIA 2NPFA 4HACA 2ZBKB 4LF7I 1KIJA 2C37B 4Z7CA 3J80Q 2PNZB 3T1YI 1PKPA 2UXBE 1IBLE 5C0XD 2BV3A 4DUYE 2X36A 4LCHA 4OO1F 3HJCA 4JI6I 2UUAE 5GMEA 1R6LA 2E5LE 3M85D 4YY3I 2R3VA 4JI2E 4B3RE 2UUBE 2JEAA 2VF3A 3P3CA 2UUCI 4NBQA 2O3ZA 4MU1A 1Y6ZA 1H74A 3D4JA 4ISAA 1H7UA 4B3MI 5C0XE 4JI7I 2ZITA 1HNZE 2JE6B 3Q6MA 4IFDB 5LL6R 2IOPA 5A2QQ 3CWVA 1KVKA 4FW3A 4X65I 4DV4E 4JYAI 3B82A 3OTOI 4IZKB 1XXEA 4DV2E 2O1TA 3ZZ0A 2V2VA 2UXDE 1R6MA 1FKAE 3ZZUA 4LF5I 1RREA 5IT9C 4N3OA 4IFDF 1B63A 4MYTA 2UXBI 2Z5EA 3PYFA 2GO4A 2VQEI 1UEKA 3ZKBA 3P3EA 2JEAB 4DV5E 4IFDA 1YH8A 4UTGA 5L3JA 4DV6I 1E3HA 4LFAE 3M85G 2E1RA 1RR9A 4X64I 2UUBI 1S4EA 4DV3E 4OO1D 2JT2A 2ZM6E 1H7SA 4B3SI 5FWKA 4IZJB 4DV7E 3J7AM 4JI7E 3J7AG 1UDSA 2NN6C 3LNUA 4X62I 3P06A 4UT4A 4AM3A 4HXZA 1HNZI 4IZKA 1U2RA 1I94I 3J81C 4X65E 4DV4I 4JYAE 5IWAE 1Z5CA 1FWLA 5K36B 1Z0TA 5K36C 1H73A 5JEAC 4DV1I 4LF5E 2VQFI 1HR0E 4AQYE 4DR3I 4FW4A 2GS8A 4IZJA 4DPUA 1ZXMA 1ZM2A 5LMUI 1XHKA 4YHHI 4OZEA 4LPFA 4OX9E 1MX0A 4KQVA 3CDJA 1XMOE 3JAMC 1QZRA 1UDOA 4HYMA 4FW7A 3J81Q 1UDNA 4P7AA 3ZM7A 4AIMA 4DU8A 5DRQA 3GONA 1USUA 4NXME 2DEIA 5C0XF 4B3SE 4U3BA 4DV7I 1WUUA 3WU6A 1B62A 4X62E 4LFBE 4FWHA 4LF9I 1Z5AA 4K0KE 4NXNE 3QT8A 1XMQI 1FNMA 1ELOA 3B8HA 5JEAF 1FWKA 3P76A 4JI0I 2PNZA 1IBLI 4USKA 1I94E 3PYDA 2HKJA 4DR6I 3ZZTA 2NN6A 3B4TA 2R42A 4JG4A 3PS1A 4DV1E 1Z0EA 2E5LI 1FJGI 3WU3A 1VISA 4XTJA 1IBKI 2VQFE 5JEAB 3H1CA 1N34I 2HK3A 3GCMA 4DPXA 1Z0WA 4MU4A 1Z59A 2Z5BB 5LMUE 5EKWA 4JI3E 4GKJI 3QT5A 3QT7A 4GKKE 1ZM3A 5K36A 1N33E 3HKMA 4DR1I 2UU9I 2F1DA 2OI2A 2V34A 2WNRB 5A2QC 2DEJA 2HKEA 2CGEA 4EMDA 2HFSA 4DV0E 3T1HE 1Z0VA 2C39B 3PS2A 3NZKA 1IBMI 2BA0D 2HHHI 5JEAE 3GMEA 4BA1B 2UXDI 4LFBI 2GQ0A 4K0KI 2X7IA 4NXNI
chains in the Genus database with same CATH topology
4QNJA 4MU3A 4GQUA 4MU0A 4LPFA 4MU1A 2AE8A 4QNKA 5ELWA 5EKWA 2F1DA 4LOMA 1RHYA 5DNXA 5DNLA 5EL9A 4MU4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QNJ A;  4MU3 A;  4GQU A;  4MU0 A;  4LPF A;  4MU1 A;  2AE8 A;  4QNK A;  5ELW A;  5EKW A;  2F1D A;  4LOM A;  1RHY A;  5DNX A;  5DNL A;  5EL9 A;  4MU4 A; 
#chains in the Genus database with same CATH topology
 1NZ0 A;  5ELW A;  1N36 E;  2PNL A;  4DPW A;  1J5E E;  4JI0 E;  4DXL A;  2HFU A;  2VQE E;  4OO1 E;  1Y4U A;  4LF6 I;  4RPF A;  4DR6 E;  4DR7 E;  1N0U A;  4DV5 I;  1PIE A;  4DPT A;  4FWG A;  4DV6 E;  4FW6 A;  4LFA I;  5JEA D;  1RHY A;  2V2Q A;  3CDI A;  2BA0 G;  2IER A;  4X64 E;  4BA2 B;  1PVG A;  3K85 A;  3J80 C;  1N34 E;  4DR4 E;  4BA1 A;  4MQY A;  3M7N D;  2ZM6 I;  3M7N G;  4QNJ A;  4JI3 I;  3V5R A;  4M1K A;  1H72 C;  4PRV A;  1Z0G A;  4LFC I;  4PU9 A;  1S16 A;  4DR1 E;  3LPS A;  1ZXN A;  2WP8 A;  5JEA A;  4Z7Y A;  5DNX A;  4JI4 E;  1OJ4 A;  2BM1 A;  2NN6 E;  4GQU A;  4MU0 A;  1MU5 A;  2V8P A;  2AE8 A;  5LMN I;  4DV0 I;  3T1H I;  2CVE A;  4JI8 I;  2NN6 B;  2BA1 G;  1Z5B A;  2IES A;  4DR2 E;  4QNK A;  5IWA I;  1IBM E;  3HUL A;  1KKH A;  2XEX A;  4R1F A;  5BR8 E;  1HR0 I;  4HAC B;  1OYS A;  5IT9 Q;  1A6F A;  3WU5 A;  1N36 I;  1DAR A;  2LJP A;  1BKN A;  4X66 E;  5EL9 A;  2UXC I;  4DUY I;  4DR7 I;  2WNR A;  3DD6 A;  2JEB B;  4OX9 I;  1NHH A;  1XMO I;  1OYR A;  3QT6 A;  1HNW E;  2UUA I;  4FW5 A;  4MU3 A;  2J7K A;  1YHC A;  2BM0 A;  1USV A;  4DUZ E;  2JEB A;  4B3R I;  4OO1 C;  4LF8 E;  4DPY A;  4WUD A;  3Q1Q A;  4JV5 I;  2Z5B A;  4JI1 I;  4MYU A;  2PO1 A;  1HNX I;  1UDQ A;  3P3G A;  4LFC E;  4B3M E;  4URL A;  3K1J A;  1K47 A;  2HK2 A;  3JAM Q;  4LF4 E;  2PO1 B;  2NN6 D;  4IFD C;  3B78 A;  5FLX Q;  1XMQ E;  1XNQ I;  3GLL A;  5DRR A;  3L7Z B;  2Z5C A;  1ZM4 A;  4JI8 E;  2CG9 A;  4DU7 A;  2C39 A;  4DR2 I;  1N32 I;  4IS9 A;  1Y4S A;  3ZKD A;  4FWD A;  2WW4 A;  2PO0 A;  3Q6N A;  2O1V A;  4KHP I;  2WP8 B;  5GMD A;  1FJG E;  1Y60 A;  1IBK E;  5BR8 I;  1HK7 A;  1Y5Y A;  2PO0 B;  4DR5 I;  2GO3 A;  4AID A;  4WUC A;  2J65 A;  4B3T E;  4X66 I;  4GKJ E;  4LCG A;  2UXC E;  1Z0B A;  3F0N A;  4GKK I;  1VI7 A;  4WUB A;  4FW9 A;  2PO2 B;  2Q2E B;  1N33 I;  1N0V C;  2UU9 E;  3L7Z A;  1HNW I;  2C38 A;  3V2U C;  4IFD D;  5DRO A;  1Z0C A;  4DUZ I;  2F4V I;  4BA2 A;  2PO2 A;  3PRY A;  4LF8 I;  1XNR E;  1E3P A;  4DV3 I;  4JV5 E;  5FLX C;  4JI1 E;  4JI5 I;  1HNX E;  4I3H A;  4USM A;  2HHH E;  3UHM A;  3KRN A;  2O1W A;  5DRP A;  4LF4 I;  2NN6 F;  5K36 E;  1EI1 A;  1XNQ E;  2BR2 B;  4OO1 A;  4LF7 E;  2O1U A;  4IFD E;  5C0X A;  1J5E I;  3T1Y E;  4HY1 A;  1NHI A;  4PRX A;  4LOM A;  4LCF A;  4LF6 E;  1N32 E;  3U1K A;  4MDT A;  2V2Z A;  5C0X B;  4JI6 E;  1P42 A;  4KHP E;  3WU4 A;  2A2C A;  4YY3 E;  4JI2 I;  4AQY I;  2Z5C B;  4DR4 I;  4DR3 E;  1EA6 A;  2BA1 D;  5K36 D;  4DR5 E;  2UUC E;  5C0X C;  3H4L A;  2EFG A;  4IZJ D;  4B3T I;  1KTV A;  4U3D A;  2A2D A;  4YHH E;  4OKG A;  1D6T A;  4P52 A;  1FI4 A;  4FN5 A;  3PYG A;  2IOQ A;  1OYP A;  2PNM A;  1MG7 A;  2VES A;  3PS3 A;  4JI4 I;  2F4V E;  5LMN E;  4ED4 A;  1XNR I;  1ZM9 A;  3LTO A;  4JI5 E;  2AJ4 A;  1NHJ A;  4NXM I;  2CZ9 A;  3M6A A;  3OTO E;  2JE6 A;  4J3D A;  3PYE A;  5K36 F;  2BR2 A;  5DNL A;  4DV2 I;  4OO1 B;  2C37 A;  2C38 B;  3U1Y A;  4LF9 E;  3K17 A;  4ZVI A;  2NPF A;  4HAC A;  2ZBK B;  4LF7 I;  1KIJ A;  2C37 B;  4Z7C A;  3J80 Q;  2PNZ B;  3T1Y I;  1PKP A;  2UXB E;  1IBL E;  5C0X D;  2BV3 A;  4DUY E;  2X36 A;  4LCH A;  4OO1 F;  3HJC A;  4JI6 I;  2UUA E;  5GME A;  1R6L A;  2E5L E;  3M85 D;  4YY3 I;  2R3V A;  4JI2 E;  4B3R E;  2UUB E;  2JEA A;  2VF3 A;  3P3C A;  2UUC I;  4NBQ A;  2O3Z A;  4MU1 A;  1Y6Z A;  1H74 A;  3D4J A;  4ISA A;  1H7U A;  4B3M I;  5C0X E;  4JI7 I;  2ZIT A;  1HNZ E;  2JE6 B;  3Q6M A;  4IFD B;  5LL6 R;  2IOP A;  5A2Q Q;  3CWV A;  1KVK A;  4FW3 A;  4X65 I;  4DV4 E;  4JYA I;  3B82 A;  3OTO I;  4IZK B;  1XXE A;  4DV2 E;  2O1T A;  3ZZ0 A;  2V2V A;  2UXD E;  1R6M A;  1FKA E;  3ZZU A;  4LF5 I;  1RRE A;  5IT9 C;  4N3O A;  4IFD F;  1B63 A;  4MYT A;  2UXB I;  2Z5E A;  3PYF A;  2GO4 A;  2VQE I;  1UEK A;  3ZKB A;  3P3E A;  2JEA B;  4DV5 E;  4IFD A;  1YH8 A;  4UTG A;  5L3J A;  4DV6 I;  1E3H A;  4LFA E;  3M85 G;  2E1R A;  1RR9 A;  4X64 I;  2UUB I;  1S4E A;  4DV3 E;  4OO1 D;  2JT2 A;  2ZM6 E;  1H7S A;  4B3S I;  5FWK A;  4IZJ B;  4DV7 E;  3J7A M;  4JI7 E;  3J7A G;  1UDS A;  2NN6 C;  3LNU A;  4X62 I;  3P06 A;  4UT4 A;  4AM3 A;  4HXZ A;  1HNZ I;  4IZK A;  1U2R A;  1I94 I;  3J81 C;  4X65 E;  4DV4 I;  4JYA E;  5IWA E;  1Z5C A;  1FWL A;  5K36 B;  1Z0T A;  5K36 C;  1H73 A;  5JEA C;  4DV1 I;  4LF5 E;  2VQF I;  1HR0 E;  4AQY E;  4DR3 I;  4FW4 A;  2GS8 A;  4IZJ A;  4DPU A;  1ZXM A;  1ZM2 A;  5LMU I;  1XHK A;  4YHH I;  4OZE A;  4LPF A;  4OX9 E;  1MX0 A;  4KQV A;  3CDJ A;  1XMO E;  3JAM C;  1QZR A;  1UDO A;  4HYM A;  4FW7 A;  3J81 Q;  1UDN A;  4P7A A;  3ZM7 A;  4AIM A;  4DU8 A;  5DRQ A;  3GON A;  1USU A;  4NXM E;  2DEI A;  5C0X F;  4B3S E;  4U3B A;  4DV7 I;  1WUU A;  3WU6 A;  1B62 A;  4X62 E;  4LFB E;  4FWH A;  4LF9 I;  1Z5A A;  4K0K E;  4NXN E;  3QT8 A;  1XMQ I;  1FNM A;  1ELO A;  3B8H A;  5JEA F;  1FWK A;  3P76 A;  4JI0 I;  2PNZ A;  1IBL I;  4USK A;  1I94 E;  3PYD A;  2HKJ A;  4DR6 I;  3ZZT A;  2NN6 A;  3B4T A;  2R42 A;  4JG4 A;  3PS1 A;  4DV1 E;  1Z0E A;  2E5L I;  1FJG I;  3WU3 A;  1VIS A;  4XTJ A;  1IBK I;  2VQF E;  5JEA B;  3H1C A;  1N34 I;  2HK3 A;  3GCM A;  4DPX A;  1Z0W A;  4MU4 A;  1Z59 A;  2Z5B B;  5LMU E;  5EKW A;  4JI3 E;  4GKJ I;  3QT5 A;  3QT7 A;  4GKK E;  1ZM3 A;  5K36 A;  1N33 E;  3HKM A;  4DR1 I;  2UU9 I;  2F1D A;  2OI2 A;  2V34 A;  2WNR B;  5A2Q C;  2DEJ A;  2HKE A;  2CGE A;  4EMD A;  2HFS A;  4DV0 E;  3T1H E;  1Z0V A;  2C39 B;  3PS2 A;  3NZK A;  1IBM I;  2BA0 D;  2HHH I;  5JEA E;  3GME A;  4BA1 B;  2UXD I;  4LFB I;  2GQ0 A;  4K0K I;  2X7I A;  4NXN I; 
#chains in the Genus database with same CATH homology
 4QNJ A;  4MU3 A;  4GQU A;  4MU0 A;  4LPF A;  4MU1 A;  2AE8 A;  4QNK A;  5ELW A;  5EKW A;  2F1D A;  4LOM A;  1RHY A;  5DNX A;  5DNL A;  5EL9 A;  4MU4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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