4MU4A

The form b structure of an e21q catalytic mutant of a. thaliana igpd2 in complex with mn2+ and its substrate, 2r3s-igp, to 1.41 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
199
structure length
199
Chain Sequence
b'SARIGEVKRETKQTNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRGGTIPSSKGVLSRS'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
total genus 63
structure length 199
sequence length 199
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu4A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu4A02
4QNKA 4MU0A 4LPFA 4QNJA 4GQUA 2F1DA 4MU4A 4MU1A 5EL9A 2AE8A 5ELWA 4LOMA 1RHYA 4MU3A 5DNLA 5EKWA 5DNXA
chains in the Genus database with same CATH superfamily
5C0XD 4YHHE 1UDSA 1S16A 1I94E 4DPTA 5IT9Q 4JG4A 2JT2A 1EA6A 1IBKE 4DV2I 1HNXE 1ZXMA 4DU8A 3U1KA 2F4VE 4JI4E 2GO4A 1WUUA 5JEAC 2AJ4A 2HFSA 2PO0B 4BA2A 2HHHI 1XMOI 2O1VA 3J80Q 1PVGA 3T1YI 1N0VC 4UTGA 4PU9A 4OX9I 1Z5BA 1FJGE 4LOMA 2C38B 4LCGA 4NXNI 5IWAE 2UXBI 2NPFA 2Z5BA 2BA0G 5JEAE 4FW9A 1XNRI 1KIJA 3K1JA 2ZM6E 1H73A 4X65E 2BA1G 4MQYA 2UXDE 3P3CA 4DR6E 3P3GA 4X64I 1PKPA 1IBLI 1PIEA 4LF7E 1OJ4A 4BA2B 3K85A 4JV5I 4WUDA 4IFDF 2V34A 2E5LI 1OYSA 1QZRA 3ZKDA 4PRVA 5LMNI 2E1RA 5A2QQ 2Z5BB 4AM3A 3PYDA 4EMDA 4GKJI 2GQ0A 3PYFA 4B3SE 3PYGA 1N34E 2A2DA 2PNLA 1HR0I 3P76A 4IZKA 4IFDB 3PYEA 4DR5E 2JEBA 4JI0E 4IFDD 3ZZUA 1Z0CA 4DR1I 1HNZE 3Q1QA 4JI2E 2CVEA 5EL9A 1XMQI 1FWKA 4JI3I 1Z5CA 1A6FA 4USMA 4X66I 4FWHA 4MDTA 2UUBE 2HFUA 4B3RI 2NN6F 3PS3A 4IZJA 4JI8I 2V2QA 5DNXA 4DV3E 2PNZA 5GMDA 4IZKB 2VQFI 2XEXA 4FN5A 4Z7YA 1HK7A 4DV0I 4HY1A 3Q6MA 2IESA 4X62E 1KKHA 3PS2A 1ELOA 1MG7A 4P7AA 4DUYI 5L3JA 1IBMI 2VESA 2NN6B 3QT7A 4DV7E 2CGEA 3WU6A 2NN6D 2BV3A 3HJCA 2O1TA 1H7UA 3KRNA 1ZM9A 1XHKA 1E3HA 2PO2A 4IZJB 4LFBI 4JI5E 3WU5A 4IZJD 3LTOA 4JI1I 2JEAA 1Z0BA 2PNZB 3H4LA 3OTOE 4LF9I 1R6MA 2WNRA 1S4EA 3K17A 1K47A 5BR8I 1P42A 1I94I 2IOQA 2J7KA 1FI4A 3J81Q 1XNQI 4HACB 4ED4A 2VF3A 3GLLA 4N3OA 4DV5E 1IBKI 1HNXI 4DR7E 2C37B 4JI7E 5JEAA 2F4VI 5K36C 3J7AG 4NXME 4LFCE 2UXCE 4P52A 3T1HE 3ZZ0A 5K36A 2PO2B 4MU0A 2HHHE 5JEAF 4B3ME 4KQVA 4DPYA 5DRPA 4GKKE 2PO1A 3T1YE 1J5EE 2CZ9A 2IERA 3CDJA 1FJGI 2EFGA 4YY3E 4K0KE 5K36E 3M6AA 1R6LA 1B63A 4B3TE 4OO1C 4U3BA 1XNRE 1N36E 2WP8A 2OI2A 2UUAE 3JAMC 5JEAB 2UXDI 4DR6I 5JEAD 4AQYE 4LF7I 1RREA 1Y4UA 4M1KA 3B78A 4LF4E 2PO1B 4LF6E 1FNMA 4OO1E 2BA0D 2V2VA 4IS9A 2DEIA 4BA1A 4J3DA 3M85G 2VQEI 2V8PA 5LMUI 2BA1D 4KHPE 5DROA 3ZZTA 4GKJE 5IT9C 2WP8B 1KTVA 1N34I 3F0NA 1FWLA 1Y6ZA 4MU3A 1ZM3A 4DV4E 1Z0GA 3HKMA 2UU9E 4DR2E 1USVA 1HNZI 4LF9E 4MU1A 1XMQE 1Y60A 1EI1A 2R42A 5GMEA 3J80C 1D6TA 4NBQA 3GMEA 4U3DA 2UUCE 4DR3E 3GONA 3PS1A 4WUCA 1N32E 1NHHA 4LPFA 4B3RE 5DRRA 5C0XC 2JEBB 4JI6E 2ZITA 4DUZE 4DV3I 4OZEA 4DV1E 1N0UA 3V2UC 3M7NG 2ZBKB 1H74A 4JYAE 4LFAE 1USUA 1H72C 4DU7A 2X36A 4DR4E 1ZM4A 4RPFA 5ELWA 4LF5E 4X62I 4ZVIA 1HNWE 2WW4A 5LL6R 5C0XE 1UDQA 4DV6E 4R1FA 3CWVA 4LF8E 4MU4A 2HKEA 1N33I 1ZXNA 4YHHI 3HULA 3H1CA 4JI5I 5FLXC 4USKA 5A2QC 3ZM7A 4JI1E 3QT5A 3ZKBA 1XXEA 3U1YA 3OTOI 4DV2E 3UHMA 2BR2A 1ZM2A 4JI4I 1B62A 5BR8E 1XNQE 2O1UA 4DV5I 4DR7I 3WU3A 4FW3A 1XMOE 5DNLA 3PRYA 4JI7I 5EKWA 2IOPA 2JEAB 4FW7A 1H7SA 1Z59A 4LFCI 4NXMI 2UXCI 4OX9E 3T1HI 2HK2A 1Y5YA 5K36F 5IWAI 4NXNE 3QT6A 2WNRB 2UXBE 4UT4A 4B3MI 4GKKI 4URLA 1FKAE 4Z7CA 1J5EI 4WUBA 2LJPA 4GQUA 1YHCA 2DEJA 2ZM6I 2Q2EB 4X65I 3WU4A 2BR2B 4YY3I 2X7IA 4K0KI 4OO1A 4AIDA 3QT8A 4MYUA 4FW4A 3V5RA 4X64E 1IBLE 4B3TI 1N36I 4I3HA 2GO3A 5K36B 2J65A 4IFDC 3LNUA 2UUAI 4OO1F 5K36D 3NZKA 4JV5E 4AQYI 4LCFA 4IFDA 1UDNA 3CDIA 2E5LE 4MYTA 2HKJA 4LF4I 5LMNE 4LF6I 5FWKA 2BM0A 1KVKA 2BM1A 2V2ZA 2C39A 2JE6A 2VQEE 4B3SI 4IFDE 5DRQA 4OO1B 5FLXQ 5LMUE 4KHPI 2GS8A 1HR0E 4OO1D 4DR5I 1RHYA 4JI0I 1UEKA 1MX0A 4ISAA 3J81C 4DR1E 2F1DA 1MU5A 1Z0VA 4JI2I 4DPXA 4DV4I 1OYRA 4FW6A 2CG9A 3D4JA 4JI3E 4AIMA 2UU9I 1VI7A 4BA1B 3L7ZA 1RR9A 1Z0TA 2AE8A 4DR2I 2O3ZA 4X66E 2NN6C 3M85D 2R3VA 4LCHA 1DARA 2UUBI 1NHIA 3GCMA 1E3PA 2HK3A 2NN6A 4JI8E 1NHJA 2C39B 2JE6B 2UUCI 4DR3I 4QNJA 1YH8A 1OYPA 2Z5CA 4FW5A 2PNMA 1N32I 5C0XA 3P06A 4QNKA 2VQFE 4OKGA 3P3EA 4HXZA 4DV0E 4JI6I 3J7AM 4DUZI 1Z0WA 2NN6E 4DV1I 2Z5EA 4PRXA 5C0XF 3B82A 4DUYE 1VISA 3JAMQ 1IBME 4DPUA 1Z0EA 4JYAI 4LFAI 1Z5AA 4DV7I 1NZ0A 2O1WA 4FWDA 4DR4I 3L7ZB 2A2CA 4LF5I 1U2RA 4HACA 1HNWI 1Y4SA 2PO0A 1BKNA 1UDOA 3B4TA 4DPWA 4LFBE 3B8HA 4DV6I 2C37A 3Q6NA 4FWGA 4XTJA 4LF8I 2Z5CB 3DD6A 4HYMA 5C0XB 4DXLA 1N33E 3LPSA 2C38A 3M7ND
chains in the Genus database with same CATH topology
4QNKA 4MU0A 4LPFA 4QNJA 4GQUA 2F1DA 4MU4A 4MU1A 5EL9A 2AE8A 5ELWA 4LOMA 1RHYA 4MU3A 5DNLA 5EKWA 5DNXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QNK A;  4MU0 A;  4LPF A;  4QNJ A;  4GQU A;  2F1D A;  4MU4 A;  4MU1 A;  5EL9 A;  2AE8 A;  5ELW A;  4LOM A;  1RHY A;  4MU3 A;  5DNL A;  5EKW A;  5DNX A; 
#chains in the Genus database with same CATH topology
 5C0X D;  4YHH E;  1UDS A;  1S16 A;  1I94 E;  4DPT A;  5IT9 Q;  4JG4 A;  2JT2 A;  1EA6 A;  1IBK E;  4DV2 I;  1HNX E;  1ZXM A;  4DU8 A;  3U1K A;  2F4V E;  4JI4 E;  2GO4 A;  1WUU A;  5JEA C;  2AJ4 A;  2HFS A;  2PO0 B;  4BA2 A;  2HHH I;  1XMO I;  2O1V A;  3J80 Q;  1PVG A;  3T1Y I;  1N0V C;  4UTG A;  4PU9 A;  4OX9 I;  1Z5B A;  1FJG E;  4LOM A;  2C38 B;  4LCG A;  4NXN I;  5IWA E;  2UXB I;  2NPF A;  2Z5B A;  2BA0 G;  5JEA E;  4FW9 A;  1XNR I;  1KIJ A;  3K1J A;  2ZM6 E;  1H73 A;  4X65 E;  2BA1 G;  4MQY A;  2UXD E;  3P3C A;  4DR6 E;  3P3G A;  4X64 I;  1PKP A;  1IBL I;  1PIE A;  4LF7 E;  1OJ4 A;  4BA2 B;  3K85 A;  4JV5 I;  4WUD A;  4IFD F;  2V34 A;  2E5L I;  1OYS A;  1QZR A;  3ZKD A;  4PRV A;  5LMN I;  2E1R A;  5A2Q Q;  2Z5B B;  4AM3 A;  3PYD A;  4EMD A;  4GKJ I;  2GQ0 A;  3PYF A;  4B3S E;  3PYG A;  1N34 E;  2A2D A;  2PNL A;  1HR0 I;  3P76 A;  4IZK A;  4IFD B;  3PYE A;  4DR5 E;  2JEB A;  4JI0 E;  4IFD D;  3ZZU A;  1Z0C A;  4DR1 I;  1HNZ E;  3Q1Q A;  4JI2 E;  2CVE A;  5EL9 A;  1XMQ I;  1FWK A;  4JI3 I;  1Z5C A;  1A6F A;  4USM A;  4X66 I;  4FWH A;  4MDT A;  2UUB E;  2HFU A;  4B3R I;  2NN6 F;  3PS3 A;  4IZJ A;  4JI8 I;  2V2Q A;  5DNX A;  4DV3 E;  2PNZ A;  5GMD A;  4IZK B;  2VQF I;  2XEX A;  4FN5 A;  4Z7Y A;  1HK7 A;  4DV0 I;  4HY1 A;  3Q6M A;  2IES A;  4X62 E;  1KKH A;  3PS2 A;  1ELO A;  1MG7 A;  4P7A A;  4DUY I;  5L3J A;  1IBM I;  2VES A;  2NN6 B;  3QT7 A;  4DV7 E;  2CGE A;  3WU6 A;  2NN6 D;  2BV3 A;  3HJC A;  2O1T A;  1H7U A;  3KRN A;  1ZM9 A;  1XHK A;  1E3H A;  2PO2 A;  4IZJ B;  4LFB I;  4JI5 E;  3WU5 A;  4IZJ D;  3LTO A;  4JI1 I;  2JEA A;  1Z0B A;  2PNZ B;  3H4L A;  3OTO E;  4LF9 I;  1R6M A;  2WNR A;  1S4E A;  3K17 A;  1K47 A;  5BR8 I;  1P42 A;  1I94 I;  2IOQ A;  2J7K A;  1FI4 A;  3J81 Q;  1XNQ I;  4HAC B;  4ED4 A;  2VF3 A;  3GLL A;  4N3O A;  4DV5 E;  1IBK I;  1HNX I;  4DR7 E;  2C37 B;  4JI7 E;  5JEA A;  2F4V I;  5K36 C;  3J7A G;  4NXM E;  4LFC E;  2UXC E;  4P52 A;  3T1H E;  3ZZ0 A;  5K36 A;  2PO2 B;  4MU0 A;  2HHH E;  5JEA F;  4B3M E;  4KQV A;  4DPY A;  5DRP A;  4GKK E;  2PO1 A;  3T1Y E;  1J5E E;  2CZ9 A;  2IER A;  3CDJ A;  1FJG I;  2EFG A;  4YY3 E;  4K0K E;  5K36 E;  3M6A A;  1R6L A;  1B63 A;  4B3T E;  4OO1 C;  4U3B A;  1XNR E;  1N36 E;  2WP8 A;  2OI2 A;  2UUA E;  3JAM C;  5JEA B;  2UXD I;  4DR6 I;  5JEA D;  4AQY E;  4LF7 I;  1RRE A;  1Y4U A;  4M1K A;  3B78 A;  4LF4 E;  2PO1 B;  4LF6 E;  1FNM A;  4OO1 E;  2BA0 D;  2V2V A;  4IS9 A;  2DEI A;  4BA1 A;  4J3D A;  3M85 G;  2VQE I;  2V8P A;  5LMU I;  2BA1 D;  4KHP E;  5DRO A;  3ZZT A;  4GKJ E;  5IT9 C;  2WP8 B;  1KTV A;  1N34 I;  3F0N A;  1FWL A;  1Y6Z A;  4MU3 A;  1ZM3 A;  4DV4 E;  1Z0G A;  3HKM A;  2UU9 E;  4DR2 E;  1USV A;  1HNZ I;  4LF9 E;  4MU1 A;  1XMQ E;  1Y60 A;  1EI1 A;  2R42 A;  5GME A;  3J80 C;  1D6T A;  4NBQ A;  3GME A;  4U3D A;  2UUC E;  4DR3 E;  3GON A;  3PS1 A;  4WUC A;  1N32 E;  1NHH A;  4LPF A;  4B3R E;  5DRR A;  5C0X C;  2JEB B;  4JI6 E;  2ZIT A;  4DUZ E;  4DV3 I;  4OZE A;  4DV1 E;  1N0U A;  3V2U C;  3M7N G;  2ZBK B;  1H74 A;  4JYA E;  4LFA E;  1USU A;  1H72 C;  4DU7 A;  2X36 A;  4DR4 E;  1ZM4 A;  4RPF A;  5ELW A;  4LF5 E;  4X62 I;  4ZVI A;  1HNW E;  2WW4 A;  5LL6 R;  5C0X E;  1UDQ A;  4DV6 E;  4R1F A;  3CWV A;  4LF8 E;  4MU4 A;  2HKE A;  1N33 I;  1ZXN A;  4YHH I;  3HUL A;  3H1C A;  4JI5 I;  5FLX C;  4USK A;  5A2Q C;  3ZM7 A;  4JI1 E;  3QT5 A;  3ZKB A;  1XXE A;  3U1Y A;  3OTO I;  4DV2 E;  3UHM A;  2BR2 A;  1ZM2 A;  4JI4 I;  1B62 A;  5BR8 E;  1XNQ E;  2O1U A;  4DV5 I;  4DR7 I;  3WU3 A;  4FW3 A;  1XMO E;  5DNL A;  3PRY A;  4JI7 I;  5EKW A;  2IOP A;  2JEA B;  4FW7 A;  1H7S A;  1Z59 A;  4LFC I;  4NXM I;  2UXC I;  4OX9 E;  3T1H I;  2HK2 A;  1Y5Y A;  5K36 F;  5IWA I;  4NXN E;  3QT6 A;  2WNR B;  2UXB E;  4UT4 A;  4B3M I;  4GKK I;  4URL A;  1FKA E;  4Z7C A;  1J5E I;  4WUB A;  2LJP A;  4GQU A;  1YHC A;  2DEJ A;  2ZM6 I;  2Q2E B;  4X65 I;  3WU4 A;  2BR2 B;  4YY3 I;  2X7I A;  4K0K I;  4OO1 A;  4AID A;  3QT8 A;  4MYU A;  4FW4 A;  3V5R A;  4X64 E;  1IBL E;  4B3T I;  1N36 I;  4I3H A;  2GO3 A;  5K36 B;  2J65 A;  4IFD C;  3LNU A;  2UUA I;  4OO1 F;  5K36 D;  3NZK A;  4JV5 E;  4AQY I;  4LCF A;  4IFD A;  1UDN A;  3CDI A;  2E5L E;  4MYT A;  2HKJ A;  4LF4 I;  5LMN E;  4LF6 I;  5FWK A;  2BM0 A;  1KVK A;  2BM1 A;  2V2Z A;  2C39 A;  2JE6 A;  2VQE E;  4B3S I;  4IFD E;  5DRQ A;  4OO1 B;  5FLX Q;  5LMU E;  4KHP I;  2GS8 A;  1HR0 E;  4OO1 D;  4DR5 I;  1RHY A;  4JI0 I;  1UEK A;  1MX0 A;  4ISA A;  3J81 C;  4DR1 E;  2F1D A;  1MU5 A;  1Z0V A;  4JI2 I;  4DPX A;  4DV4 I;  1OYR A;  4FW6 A;  2CG9 A;  3D4J A;  4JI3 E;  4AIM A;  2UU9 I;  1VI7 A;  4BA1 B;  3L7Z A;  1RR9 A;  1Z0T A;  2AE8 A;  4DR2 I;  2O3Z A;  4X66 E;  2NN6 C;  3M85 D;  2R3V A;  4LCH A;  1DAR A;  2UUB I;  1NHI A;  3GCM A;  1E3P A;  2HK3 A;  2NN6 A;  4JI8 E;  1NHJ A;  2C39 B;  2JE6 B;  2UUC I;  4DR3 I;  4QNJ A;  1YH8 A;  1OYP A;  2Z5C A;  4FW5 A;  2PNM A;  1N32 I;  5C0X A;  3P06 A;  4QNK A;  2VQF E;  4OKG A;  3P3E A;  4HXZ A;  4DV0 E;  4JI6 I;  3J7A M;  4DUZ I;  1Z0W A;  2NN6 E;  4DV1 I;  2Z5E A;  4PRX A;  5C0X F;  3B82 A;  4DUY E;  1VIS A;  3JAM Q;  1IBM E;  4DPU A;  1Z0E A;  4JYA I;  4LFA I;  1Z5A A;  4DV7 I;  1NZ0 A;  2O1W A;  4FWD A;  4DR4 I;  3L7Z B;  2A2C A;  4LF5 I;  1U2R A;  4HAC A;  1HNW I;  1Y4S A;  2PO0 A;  1BKN A;  1UDO A;  3B4T A;  4DPW A;  4LFB E;  3B8H A;  4DV6 I;  2C37 A;  3Q6N A;  4FWG A;  4XTJ A;  4LF8 I;  2Z5C B;  3DD6 A;  4HYM A;  5C0X B;  4DXL A;  1N33 E;  3LPS A;  2C38 A;  3M7N D; 
#chains in the Genus database with same CATH homology
 4QNK A;  4MU0 A;  4LPF A;  4QNJ A;  4GQU A;  2F1D A;  4MU4 A;  4MU1 A;  5EL9 A;  2AE8 A;  5ELW A;  4LOM A;  1RHY A;  4MU3 A;  5DNL A;  5EKW A;  5DNX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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