4MU4A

The form b structure of an e21q catalytic mutant of a. thaliana igpd2 in complex with mn2+ and its substrate, 2r3s-igp, to 1.41 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
199
structure length
199
Chain Sequence
SARIGEVKRETKQTNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRGGTIPSSKGVLSRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
total genus 63
structure length 199
sequence length 199
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu4A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu4A02
2F1DA 4MU0A 4MU1A 4MU3A 1RHYA 4MU4A 5EL9A 4QNJA 5EKWA 4GQUA 5DNLA 5DNXA 2AE8A 4QNKA 4LOMA 4LPFA 5ELWA
chains in the Genus database with same CATH superfamily
4LFBI 1N33I 4DUZE 4B3TI 3T1HE 4FWHA 3GCMA 5DRQA 4FW9A 3K85A 4DV7I 2UUBE 2BR2A 4LF9I 2BR2B 1XNQE 2UU9E 4JI1E 4LF6E 4FW6A 4YHHE 1Z5BA 1FWKA 4WUDA 4LF5E 1PVGA 3CDIA 1UEKA 4NBQA 3OTOE 1XNRI 1FKAE 1IBKE 1ZXNA 5EL9A 2JT2A 5IWAE 2JE6B 1HNXI 2R42A 4MYTA 5LMUE 1FJGI 4FWGA 1HR0I 1Y4UA 4OO1E 1OJ4A 3NZKA 2O3ZA 2PO0A 3P3CA 4KHPE 1R6MA 4HXZA 4B3RI 5K36D 1J5EI 3CWVA 2O1WA 2UUCE 4LF7I 2O1TA 2UXDI 1NZ0A 2ZITA 1OYSA 1E3PA 4DV2I 2F1DA 4K0KI 1MG7A 3K17A 4OO1C 3WU5A 5JEAB 2WW4A 4FWDA 2F4VE 1RR9A 4DPTA 3ZM7A 4BA1B 1ZM2A 1EA6A 5DROA 4B3MI 2CVEA 1KIJA 4OO1A 4LF4E 4JV5I 1B63A 4DV1E 2HHHI 3J80C 4JI8I 1HNWI 1KTVA 1N32I 1IBME 4LPFA 1XXEA 3WU4A 4X62I 1D6TA 1IBLE 4FN5A 5LMNE 4UT4A 5JEAF 4DR4I 5IT9C 3HULA 4IFDE 4I3HA 2VF3A 3PYFA 2GS8A 2C39A 4JI6I 2BA0D 1P42A 4LFAI 2E5LI 2HFUA 4DR2I 3P3GA 2UXBI 2Z5BB 1NHIA 2VESA 2Q2EB 4YY3E 4X66I 4IZKB 3M7ND 1N0UA 3J81C 4JI2I 2ZBKB 4OO1F 3H1CA 4EMDA 4OX9I 1N36E 2BA0G 2ZM6E 4IFDC 5DRRA 4DV0I 4LF8E 4P7AA 4USKA 4JYAI 4DU7A 1H7SA 3J80Q 3Q1QA 4DUYE 4PU9A 3B78A 4Z7CA 3M7NG 1PKPA 4FW3A 3WU3A 4HY1A 4OO1D 4JI4I 4DR3I 1I94E 2JEAA 5IT9Q 2JEBB 4JI5E 1A6FA 3PRYA 1FNMA 3P76A 2GO4A 1UDOA 4X65E 2X7IA 1S16A 4IFDA 2NN6E 5BR8I 4MU4A 3J81Q 1Y60A 5JEAE 4B3SE 1Y5YA 4MQYA 2A2CA 5A2QC 2HK3A 4JI7E 3PYDA 3T1YI 1Z5CA 2Z5CB 4NXNI 4U3BA 2WP8B 2PO1B 4DPYA 2UU9I 4DV5I 4LF6I 2JE6A 4LFBE 1N33E 1MU5A 4B3TE 1H7UA 1MX0A 3L7ZB 2PO2B 1RHYA 4DV7E 2UXCI 3M6AA 4LF9E 4DXLA 2V2VA 1XHKA 2NN6C 2A2DA 3GLLA 1HNZI 5JEAC 4IFDF 1FWLA 5C0XE 2IOPA 3D4JA 1ZM4A 4GKKE 2HKJA 2HK2A 2LJPA 1FJGE 3LTOA 5A2QQ 1N34I 2AJ4A 4IFDD 4Z7YA 2NN6B 4KQVA 3H4LA 4LCHA 2VQEI 4JI0E 1BKNA 2GQ0A 2OI2A 3U1KA 5JEAA 1ZXMA 1USVA 4GKJI 4AQYE 1XMOI 1J5EE 5C0XC 3Q6MA 3PS1A 4LF7E 1WUUA 1R6LA 4MU0A 1DARA 2UXDE 4BA1A 2X36A 4PRXA 1K47A 2F4VI 4QNJA 2VQFI 1OYPA 3ZKDA 3B8HA 4RPFA 4DV4I 2EFGA 2UUAE 4GQUA 1RREA 2NN6F 2BA1G 5DNXA 4IS9A 5C0XB 1UDNA 4MDTA 1EI1A 2C38A 1XMQE 4AIDA 2C38B 4LFCI 4DPXA 4B3ME 4J3DA 2DEIA 1Z0BA 1H72C 1IBLI 5FLXC 4DPUA 5DNLA 1HNWE 4JI8E 4ED4A 4DV3I 3HJCA 4DR7I 1N32E 1ELOA 3QT6A 1OYRA 2Z5BA 4X62E 4X64I 4IZKA 5JEAD 4IZJB 4MU3A 4M1KA 5K36E 4YY3I 3U1YA 2BV3A 2C37B 2J7KA 3GMEA 4LFAE 2E5LE 4USMA 5C0XF 4DR2E 2UXBE 2AE8A 2J65A 3PS2A 3QT7A 4LOMA 4DR6I 4X66E 5FWKA 2O1UA 3V5RA 3J7AG 4MU1A 4DR5I 4JG4A 4P52A 2JEBA 3P3EA 4OX9E 1PIEA 4AM3A 5ELWA 4JYAE 5FLXQ 4DV0E 4BA2B 2O1VA 4URLA 1UDSA 5K36C 3M85G 3GONA 3P06A 4DV6E 4NXMI 4QNKA 1Z0WA 4JI3I 3HKMA 4HYMA 1H74A 1Z59A 3QT8A 4JI4E 4DR3E 4PRVA 2PNMA 4DR1E 2Z5CA 4DUZI 2WNRA 3T1HI 2WNRB 2PNZB 2WP8A 4ZVIA 2BM0A 2UUBI 2PO1A 1XNQI 4JI1I 5BR8E 2GO3A 5K36A 3KRNA 4YHHI 5K36B 4LF5I 3JAMC 3L7ZA 3OTOI 2PO2A 1KVKA 5LL6R 1IBKI 1KKHA 3T1YE 5IWAI 4NXNE 2PNLA 1ZM9A 2CG9A 1XNRE 1N0VC 4DV5E 5LMUI 2V8PA 1Y4SA 3ZZ0A 1USUA 1HNXE 2UXCE 1Z0TA 4KHPI 4ISAA 1HR0E 1Z0EA 5DRPA 3QT5A 1Y6ZA 3LPSA 2IESA 1HNZE 4GKKI 1NHJA 2NN6A 3ZZUA 5K36F 2HKEA 2IERA 2UUCI 1HK7A 1VI7A 3B82A 2PO0B 2BM1A 4B3RE 4JI0I 5L3JA 4WUBA 3JAMQ 4AIMA 3B4TA 1N34E 1QZRA 2BA1D 3PS3A 3ZKBA 1YHCA 4AQYI 4DV2E 4K0KE 2VQEE 4HACA 4HACB 5EKWA 2XEXA 3PYGA 4GKJE 1XMOE 2Z5EA 4LCFA 2IOQA 4MYUA 3WU6A 5C0XA 3V2UC 3ZZTA 4LF4I 2VQFE 4DV1I 2UUAI 3CDJA 1IBMI 1H73A 1VISA 4DV4E 3K1JA 1XMQI 5LMNI 1E3HA 4JV5E 2HFSA 4XTJA 2HHHE 1NHHA 2NN6D 3J7AM 1Z0GA 2CGEA 2DEJA 3Q6NA 4OO1B 4IZJA 4LFCE 4DR4E 2V2ZA 4FW5A 1B62A 2C37A 4DPWA 4JI6E 1U2RA 4DV3E 4DR7E 1UDQA 2CZ9A 3M85D 4FW4A 4X64E 4DU8A 3F0NA 4UTGA 2C39B 1N36I 4JI2E 2ZM6I 1S4EA 4LF8I 4FW7A 5GMDA 4U3DA 4DUYI 5C0XD 1Z0CA 2V34A 4BA2A 1Z5AA 4DR6E 1I94I 4JI5I 4R1FA 1Z0VA 5GMEA 4DR5E 3LNUA 4DV6I 4X65I 2E1RA 3DD6A 4IZJD 4N3OA 2R3VA 3UHMA 2PNZA 2JEAB 3PYEA 4B3SI 4NXME 4DR1I 4JI3E 4JI7I 4LCGA 4OZEA 1FI4A 1ZM3A 4OKGA 4WUCA 2V2QA 4IFDB 2NPFA 1YH8A
chains in the Genus database with same CATH topology
2F1DA 4MU0A 4MU1A 4MU3A 1RHYA 4MU4A 5EL9A 4QNJA 5EKWA 4GQUA 5DNLA 5DNXA 2AE8A 4QNKA 4LOMA 4LPFA 5ELWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1D A;  4MU0 A;  4MU1 A;  4MU3 A;  1RHY A;  4MU4 A;  5EL9 A;  4QNJ A;  5EKW A;  4GQU A;  5DNL A;  5DNX A;  2AE8 A;  4QNK A;  4LOM A;  4LPF A;  5ELW A; 
#chains in the Genus database with same CATH topology
 4LFB I;  1N33 I;  4DUZ E;  4B3T I;  3T1H E;  4FWH A;  3GCM A;  5DRQ A;  4FW9 A;  3K85 A;  4DV7 I;  2UUB E;  2BR2 A;  4LF9 I;  2BR2 B;  1XNQ E;  2UU9 E;  4JI1 E;  4LF6 E;  4FW6 A;  4YHH E;  1Z5B A;  1FWK A;  4WUD A;  4LF5 E;  1PVG A;  3CDI A;  1UEK A;  4NBQ A;  3OTO E;  1XNR I;  1FKA E;  1IBK E;  1ZXN A;  5EL9 A;  2JT2 A;  5IWA E;  2JE6 B;  1HNX I;  2R42 A;  4MYT A;  5LMU E;  1FJG I;  4FWG A;  1HR0 I;  1Y4U A;  4OO1 E;  1OJ4 A;  3NZK A;  2O3Z A;  2PO0 A;  3P3C A;  4KHP E;  1R6M A;  4HXZ A;  4B3R I;  5K36 D;  1J5E I;  3CWV A;  2O1W A;  2UUC E;  4LF7 I;  2O1T A;  2UXD I;  1NZ0 A;  2ZIT A;  1OYS A;  1E3P A;  4DV2 I;  2F1D A;  4K0K I;  1MG7 A;  3K17 A;  4OO1 C;  3WU5 A;  5JEA B;  2WW4 A;  4FWD A;  2F4V E;  1RR9 A;  4DPT A;  3ZM7 A;  4BA1 B;  1ZM2 A;  1EA6 A;  5DRO A;  4B3M I;  2CVE A;  1KIJ A;  4OO1 A;  4LF4 E;  4JV5 I;  1B63 A;  4DV1 E;  2HHH I;  3J80 C;  4JI8 I;  1HNW I;  1KTV A;  1N32 I;  1IBM E;  4LPF A;  1XXE A;  3WU4 A;  4X62 I;  1D6T A;  1IBL E;  4FN5 A;  5LMN E;  4UT4 A;  5JEA F;  4DR4 I;  5IT9 C;  3HUL A;  4IFD E;  4I3H A;  2VF3 A;  3PYF A;  2GS8 A;  2C39 A;  4JI6 I;  2BA0 D;  1P42 A;  4LFA I;  2E5L I;  2HFU A;  4DR2 I;  3P3G A;  2UXB I;  2Z5B B;  1NHI A;  2VES A;  2Q2E B;  4YY3 E;  4X66 I;  4IZK B;  3M7N D;  1N0U A;  3J81 C;  4JI2 I;  2ZBK B;  4OO1 F;  3H1C A;  4EMD A;  4OX9 I;  1N36 E;  2BA0 G;  2ZM6 E;  4IFD C;  5DRR A;  4DV0 I;  4LF8 E;  4P7A A;  4USK A;  4JYA I;  4DU7 A;  1H7S A;  3J80 Q;  3Q1Q A;  4DUY E;  4PU9 A;  3B78 A;  4Z7C A;  3M7N G;  1PKP A;  4FW3 A;  3WU3 A;  4HY1 A;  4OO1 D;  4JI4 I;  4DR3 I;  1I94 E;  2JEA A;  5IT9 Q;  2JEB B;  4JI5 E;  1A6F A;  3PRY A;  1FNM A;  3P76 A;  2GO4 A;  1UDO A;  4X65 E;  2X7I A;  1S16 A;  4IFD A;  2NN6 E;  5BR8 I;  4MU4 A;  3J81 Q;  1Y60 A;  5JEA E;  4B3S E;  1Y5Y A;  4MQY A;  2A2C A;  5A2Q C;  2HK3 A;  4JI7 E;  3PYD A;  3T1Y I;  1Z5C A;  2Z5C B;  4NXN I;  4U3B A;  2WP8 B;  2PO1 B;  4DPY A;  2UU9 I;  4DV5 I;  4LF6 I;  2JE6 A;  4LFB E;  1N33 E;  1MU5 A;  4B3T E;  1H7U A;  1MX0 A;  3L7Z B;  2PO2 B;  1RHY A;  4DV7 E;  2UXC I;  3M6A A;  4LF9 E;  4DXL A;  2V2V A;  1XHK A;  2NN6 C;  2A2D A;  3GLL A;  1HNZ I;  5JEA C;  4IFD F;  1FWL A;  5C0X E;  2IOP A;  3D4J A;  1ZM4 A;  4GKK E;  2HKJ A;  2HK2 A;  2LJP A;  1FJG E;  3LTO A;  5A2Q Q;  1N34 I;  2AJ4 A;  4IFD D;  4Z7Y A;  2NN6 B;  4KQV A;  3H4L A;  4LCH A;  2VQE I;  4JI0 E;  1BKN A;  2GQ0 A;  2OI2 A;  3U1K A;  5JEA A;  1ZXM A;  1USV A;  4GKJ I;  4AQY E;  1XMO I;  1J5E E;  5C0X C;  3Q6M A;  3PS1 A;  4LF7 E;  1WUU A;  1R6L A;  4MU0 A;  1DAR A;  2UXD E;  4BA1 A;  2X36 A;  4PRX A;  1K47 A;  2F4V I;  4QNJ A;  2VQF I;  1OYP A;  3ZKD A;  3B8H A;  4RPF A;  4DV4 I;  2EFG A;  2UUA E;  4GQU A;  1RRE A;  2NN6 F;  2BA1 G;  5DNX A;  4IS9 A;  5C0X B;  1UDN A;  4MDT A;  1EI1 A;  2C38 A;  1XMQ E;  4AID A;  2C38 B;  4LFC I;  4DPX A;  4B3M E;  4J3D A;  2DEI A;  1Z0B A;  1H72 C;  1IBL I;  5FLX C;  4DPU A;  5DNL A;  1HNW E;  4JI8 E;  4ED4 A;  4DV3 I;  3HJC A;  4DR7 I;  1N32 E;  1ELO A;  3QT6 A;  1OYR A;  2Z5B A;  4X62 E;  4X64 I;  4IZK A;  5JEA D;  4IZJ B;  4MU3 A;  4M1K A;  5K36 E;  4YY3 I;  3U1Y A;  2BV3 A;  2C37 B;  2J7K A;  3GME A;  4LFA E;  2E5L E;  4USM A;  5C0X F;  4DR2 E;  2UXB E;  2AE8 A;  2J65 A;  3PS2 A;  3QT7 A;  4LOM A;  4DR6 I;  4X66 E;  5FWK A;  2O1U A;  3V5R A;  3J7A G;  4MU1 A;  4DR5 I;  4JG4 A;  4P52 A;  2JEB A;  3P3E A;  4OX9 E;  1PIE A;  4AM3 A;  5ELW A;  4JYA E;  5FLX Q;  4DV0 E;  4BA2 B;  2O1V A;  4URL A;  1UDS A;  5K36 C;  3M85 G;  3GON A;  3P06 A;  4DV6 E;  4NXM I;  4QNK A;  1Z0W A;  4JI3 I;  3HKM A;  4HYM A;  1H74 A;  1Z59 A;  3QT8 A;  4JI4 E;  4DR3 E;  4PRV A;  2PNM A;  4DR1 E;  2Z5C A;  4DUZ I;  2WNR A;  3T1H I;  2WNR B;  2PNZ B;  2WP8 A;  4ZVI A;  2BM0 A;  2UUB I;  2PO1 A;  1XNQ I;  4JI1 I;  5BR8 E;  2GO3 A;  5K36 A;  3KRN A;  4YHH I;  5K36 B;  4LF5 I;  3JAM C;  3L7Z A;  3OTO I;  2PO2 A;  1KVK A;  5LL6 R;  1IBK I;  1KKH A;  3T1Y E;  5IWA I;  4NXN E;  2PNL A;  1ZM9 A;  2CG9 A;  1XNR E;  1N0V C;  4DV5 E;  5LMU I;  2V8P A;  1Y4S A;  3ZZ0 A;  1USU A;  1HNX E;  2UXC E;  1Z0T A;  4KHP I;  4ISA A;  1HR0 E;  1Z0E A;  5DRP A;  3QT5 A;  1Y6Z A;  3LPS A;  2IES A;  1HNZ E;  4GKK I;  1NHJ A;  2NN6 A;  3ZZU A;  5K36 F;  2HKE A;  2IER A;  2UUC I;  1HK7 A;  1VI7 A;  3B82 A;  2PO0 B;  2BM1 A;  4B3R E;  4JI0 I;  5L3J A;  4WUB A;  3JAM Q;  4AIM A;  3B4T A;  1N34 E;  1QZR A;  2BA1 D;  3PS3 A;  3ZKB A;  1YHC A;  4AQY I;  4DV2 E;  4K0K E;  2VQE E;  4HAC A;  4HAC B;  5EKW A;  2XEX A;  3PYG A;  4GKJ E;  1XMO E;  2Z5E A;  4LCF A;  2IOQ A;  4MYU A;  3WU6 A;  5C0X A;  3V2U C;  3ZZT A;  4LF4 I;  2VQF E;  4DV1 I;  2UUA I;  3CDJ A;  1IBM I;  1H73 A;  1VIS A;  4DV4 E;  3K1J A;  1XMQ I;  5LMN I;  1E3H A;  4JV5 E;  2HFS A;  4XTJ A;  2HHH E;  1NHH A;  2NN6 D;  3J7A M;  1Z0G A;  2CGE A;  2DEJ A;  3Q6N A;  4OO1 B;  4IZJ A;  4LFC E;  4DR4 E;  2V2Z A;  4FW5 A;  1B62 A;  2C37 A;  4DPW A;  4JI6 E;  1U2R A;  4DV3 E;  4DR7 E;  1UDQ A;  2CZ9 A;  3M85 D;  4FW4 A;  4X64 E;  4DU8 A;  3F0N A;  4UTG A;  2C39 B;  1N36 I;  4JI2 E;  2ZM6 I;  1S4E A;  4LF8 I;  4FW7 A;  5GMD A;  4U3D A;  4DUY I;  5C0X D;  1Z0C A;  2V34 A;  4BA2 A;  1Z5A A;  4DR6 E;  1I94 I;  4JI5 I;  4R1F A;  1Z0V A;  5GME A;  4DR5 E;  3LNU A;  4DV6 I;  4X65 I;  2E1R A;  3DD6 A;  4IZJ D;  4N3O A;  2R3V A;  3UHM A;  2PNZ A;  2JEA B;  3PYE A;  4B3S I;  4NXM E;  4DR1 I;  4JI3 E;  4JI7 I;  4LCG A;  4OZE A;  1FI4 A;  1ZM3 A;  4OKG A;  4WUC A;  2V2Q A;  4IFD B;  2NPF A;  1YH8 A; 
#chains in the Genus database with same CATH homology
 2F1D A;  4MU0 A;  4MU1 A;  4MU3 A;  1RHY A;  4MU4 A;  5EL9 A;  4QNJ A;  5EKW A;  4GQU A;  5DNL A;  5DNX A;  2AE8 A;  4QNK A;  4LOM A;  4LPF A;  5ELW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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