4MU4A

The form b structure of an e21q catalytic mutant of a. thaliana igpd2 in complex with mn2+ and its substrate, 2r3s-igp, to 1.41 a resolution
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
199
structure length
199
Chain Sequence
SARIGEVKRETKQTNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRGGTIPSSKGVLSRS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
total genus 63
structure length 199
sequence length 199
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu4A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu4A02
4QNJA 4QNKA 4LPFA 5DNXA 5DNLA 1RHYA 4MU4A 2AE8A 4MU1A 5EL9A 5ELWA 4MU3A 4GQUA 4LOMA 2F1DA 4MU0A 5EKWA
chains in the Genus database with same CATH superfamily
4FW5A 1N34E 2WP8B 3GMEA 2C39A 2BV3A 1I94I 4FWGA 4IFDB 2A2CA 5L3JA 4DV4E 4JI0I 4X65E 5K36F 4R1FA 3JAMQ 1ZM2A 5IWAE 3T1HI 4DV1I 1XMQI 4B3TI 4OO1A 4DR7I 4KHPE 5EKWA 2EFGA 1D6TA 3V2UC 2NN6C 3H1CA 1H73A 1OYRA 4DR2I 3K85A 3B8HA 2V8PA 4WUCA 4DUZE 4DU7A 4NXME 1KVKA 4IZKB 4DR6E 4WUDA 2NN6A 2HFUA 3V5RA 4DPYA 3ZZTA 1RHYA 4DR1I 1UDOA 1YHCA 4DUYE 1J5EE 4X66I 3M7NG 4AM3A 1YH8A 4LFAI 4DPWA 2O1WA 1A6FA 4JI3I 1XHKA 4AQYI 2GS8A 1RREA 4YHHE 3ZZ0A 2NN6B 5IT9C 4DUYI 3WU6A 4DV4I 1R6LA 1N32I 3WU3A 4LFAE 1Y60A 3L7ZA 2WNRB 4DR5I 3PYGA 3K17A 3GLLA 4MU0A 4NXNI 2VQFE 4URLA 4IFDC 5BR8I 2IESA 2CZ9A 5LMNI 2HK3A 2JEAB 4FW4A 4JI1E 1FWKA 2AE8A 4B3MI 3J81C 1MU5A 2NPFA 4LF9I 1HNXI 4DR4E 2BR2B 3GONA 4ISAA 2JT2A 1R6MA 2R42A 4RPFA 1IBLE 4U3BA 4BA2B 2BA1G 4LF9E 4KQVA 3QT8A 4JV5E 5DROA 2VQEE 2PO1B 4LCHA 4IFDA 1QZRA 2DEIA 5DRPA 4JI7I 1ZXNA 2PO2A 2C37A 4PU9A 5FLXC 3QT6A 2F1DA 3GCMA 1Y5YA 3KRNA 4HXZA 4DV6I 2HHHE 5K36B 1XMOE 3LNUA 4IFDF 4JV5I 1KTVA 4AIMA 2PO0B 4X65I 4X64E 4JI0E 2UXCE 5LL6R 3U1KA 4UTGA 3M7ND 4LF4I 1XMOI 1S16A 4IS9A 4MU4A 5A2QQ 4LF7I 1HNWE 2IOPA 2WNRA 4GKKE 2UXCI 1HR0I 1H72C 2PO0A 3CWVA 5JEAF 4LFBI 1WUUA 4NXNE 5ELWA 2BM1A 1NHIA 5LMUI 3PYEA 2WP8A 3PRYA 3T1HE 4HYMA 2ZBKB 4DV7I 2C38B 4JI6I 4USKA 2IERA 1XNQE 2CVEA 4K0KI 1ZM3A 3NZKA 1ELOA 4LF6I 5A2QC 3Q6MA 3T1YE 4B3SE 1H7UA 1FJGI 1RR9A 3PS1A 2CG9A 2VQEI 2HK2A 4NBQA 4JI7E 4IZKA 4OX9E 1N0UA 5K36A 1Y4SA 1EA6A 1XXEA 5JEAB 2NN6E 3T1YI 2UUBI 5FLXQ 4YHHI 4HACA 5C0XB 2UXDI 1K47A 3WU4A 1OYPA 1B62A 1PKPA 4GKJI 4DU8A 2JEBA 2O1TA 2Z5CB 4FW6A 5DNXA 2NN6F 3ZKBA 1USVA 2Z5CA 1J5EI 4PRXA 4X66E 2UUAE 4IFDE 5EL9A 4JI8I 5C0XF 1PVGA 1FJGE 3HULA 2BA0D 2JEBB 2V34A 1BKNA 3CDJA 4OO1E 2BA1D 2V2ZA 3P76A 4UT4A 2JEAA 2C39B 1Z0BA 1U2RA 4P7AA 1KKHA 3B78A 2V2VA 2IOQA 4MU1A 4Z7YA 1N0VC 2LJPA 1IBKE 3L7ZB 1Z0VA 4LPFA 1USUA 5DRQA 1DARA 1XNQI 4LF5E 3OTOI 1Z0GA 1B63A 4M1KA 1NHJA 5IT9Q 1Z0CA 4JI3E 4B3ME 2E5LI 2HKJA 4OO1C 2HHHI 2ZM6E 3Q6NA 2PO2B 2BR2A 5DRRA 4DR5E 1IBLI 4JI5I 4LCFA 4OO1B 1IBME 4IFDD 3J81Q 1OJ4A 1FNMA 4IZJA 1E3HA 2GQ0A 2ZITA 4MU3A 4DV0E 1HNZI 2UXBE 4IZJB 4LF6E 4DV1E 4DR7E 4KHPI 4P52A 4B3RE 4BA1B 1Z5BA 4QNJA 3LTOA 4WUBA 2UXBI 3F0NA 3JAMC 1NHHA 2J65A 3B4TA 1N36E 4FW7A 2X36A 1MG7A 4DR3I 1Z59A 4DV5I 1EI1A 2F4VI 3QT7A 4FWDA 4LF7E 1HNWI 5JEAE 4ED4A 3HJCA 2BA0G 5IWAI 1N33I 4GKJE 4DV3E 4LOMA 1IBKI 4AIDA 2O1VA 5C0XD 4LF5I 4U3DA 1UEKA 5K36E 3M6AA 4X64I 5C0XC 2HKEA 4OX9I 4DV3I 2A2DA 4DR6I 2J7KA 1XNRE 3PYFA 3M85D 2DEJA 3PS2A 2PO1A 2AJ4A 4FW9A 3J80Q 2ZM6I 5GMDA 5BR8E 2C38A 4J3DA 2R3VA 5LMNE 1HR0E 3DD6A 3U1YA 1N36I 5FWKA 4BA2A 5JEAA 4YY3E 1ZM4A 4DR3E 2Z5BA 1XNRI 3LPSA 4B3SI 4HACB 5GMEA 4MYUA 3ZM7A 2UUCE 4GQUA 2UU9E 3P3CA 3UHMA 4B3RI 4LCGA 4DPTA 2PNMA 3K1JA 4JI4I 1I94E 2UXDE 2NN6D 1FWLA 3PYDA 4OKGA 4PRVA 3WU5A 4LFCI 4EMDA 4JI2E 5K36D 3P3EA 3ZKDA 4FW3A 5DNLA 4LFBE 4DV5E 2V2QA 4JI4E 2E1RA 2HFSA 1PIEA 3P06A 1N32E 2X7IA 2GO4A 1UDSA 3H4LA 1Z5AA 2WW4A 4MYTA 3ZZUA 4DV7E 2UUBE 1ZM9A 4X62I 4DR1E 1H74A 4K0KE 4DXLA 3PS3A 1P42A 4FWHA 1VI7A 4OO1F 1Z5CA 4XTJA 4JI1I 4JI5E 4OO1D 1FI4A 1ZXMA 4DV6E 3QT5A 2F4VE 4IZJD 4DR2E 1H7SA 3D4JA 4DPUA 5LMUE 2UUAI 2Z5BB 1VISA 2PNZA 4JG4A 4JI8E 4USMA 4N3OA 4HY1A 2XEXA 5C0XA 4JI6E 1E3PA 4QNKA 1MX0A 2UUCI 1S4EA 2C37B 1XMQE 4BA1A 1UDNA 4B3TE 4OZEA 4AQYE 3Q1QA 4MDTA 1IBMI 1Z0WA 2O3ZA 4DR4I 2JE6A 4DV2E 4I3HA 2PNLA 4JYAI 3B82A 3J7AG 1Y6ZA 1KIJA 4DUZI 4JI2I 4LFCE 2E5LE 4DPXA 2VF3A 4LF4E 1Y4UA 2Z5EA 1UDQA 2CGEA 4JYAE 4FN5A 3M85G 4GKKI 2UU9I 2JE6B 4LF8E 2VESA 5JEAC 3CDIA 3J80C 2O1UA 1Z0TA 1HNXE 5JEAD 3OTOE 4X62E 4DV0I 4Z7CA 1HNZE 1FKAE 3J7AM 3P3GA 3HKMA 2OI2A 4ZVIA 2Q2EB 4LF8I 1N33E 4YY3I 1N34I 1Z0EA 4NXMI 5C0XE 5K36C 1NZ0A 1OYSA 1HK7A 2GO3A 2VQFI 4DV2I 4MQYA 2PNZB 2BM0A
chains in the Genus database with same CATH topology
4QNJA 4QNKA 4LPFA 5DNXA 5DNLA 1RHYA 4MU4A 2AE8A 4MU1A 5EL9A 5ELWA 4MU3A 4GQUA 4LOMA 2F1DA 4MU0A 5EKWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QNJ A;  4QNK A;  4LPF A;  5DNX A;  5DNL A;  1RHY A;  4MU4 A;  2AE8 A;  4MU1 A;  5EL9 A;  5ELW A;  4MU3 A;  4GQU A;  4LOM A;  2F1D A;  4MU0 A;  5EKW A; 
#chains in the Genus database with same CATH topology
 4FW5 A;  1N34 E;  2WP8 B;  3GME A;  2C39 A;  2BV3 A;  1I94 I;  4FWG A;  4IFD B;  2A2C A;  5L3J A;  4DV4 E;  4JI0 I;  4X65 E;  5K36 F;  4R1F A;  3JAM Q;  1ZM2 A;  5IWA E;  3T1H I;  4DV1 I;  1XMQ I;  4B3T I;  4OO1 A;  4DR7 I;  4KHP E;  5EKW A;  2EFG A;  1D6T A;  3V2U C;  2NN6 C;  3H1C A;  1H73 A;  1OYR A;  4DR2 I;  3K85 A;  3B8H A;  2V8P A;  4WUC A;  4DUZ E;  4DU7 A;  4NXM E;  1KVK A;  4IZK B;  4DR6 E;  4WUD A;  2NN6 A;  2HFU A;  3V5R A;  4DPY A;  3ZZT A;  1RHY A;  4DR1 I;  1UDO A;  1YHC A;  4DUY E;  1J5E E;  4X66 I;  3M7N G;  4AM3 A;  1YH8 A;  4LFA I;  4DPW A;  2O1W A;  1A6F A;  4JI3 I;  1XHK A;  4AQY I;  2GS8 A;  1RRE A;  4YHH E;  3ZZ0 A;  2NN6 B;  5IT9 C;  4DUY I;  3WU6 A;  4DV4 I;  1R6L A;  1N32 I;  3WU3 A;  4LFA E;  1Y60 A;  3L7Z A;  2WNR B;  4DR5 I;  3PYG A;  3K17 A;  3GLL A;  4MU0 A;  4NXN I;  2VQF E;  4URL A;  4IFD C;  5BR8 I;  2IES A;  2CZ9 A;  5LMN I;  2HK3 A;  2JEA B;  4FW4 A;  4JI1 E;  1FWK A;  2AE8 A;  4B3M I;  3J81 C;  1MU5 A;  2NPF A;  4LF9 I;  1HNX I;  4DR4 E;  2BR2 B;  3GON A;  4ISA A;  2JT2 A;  1R6M A;  2R42 A;  4RPF A;  1IBL E;  4U3B A;  4BA2 B;  2BA1 G;  4LF9 E;  4KQV A;  3QT8 A;  4JV5 E;  5DRO A;  2VQE E;  2PO1 B;  4LCH A;  4IFD A;  1QZR A;  2DEI A;  5DRP A;  4JI7 I;  1ZXN A;  2PO2 A;  2C37 A;  4PU9 A;  5FLX C;  3QT6 A;  2F1D A;  3GCM A;  1Y5Y A;  3KRN A;  4HXZ A;  4DV6 I;  2HHH E;  5K36 B;  1XMO E;  3LNU A;  4IFD F;  4JV5 I;  1KTV A;  4AIM A;  2PO0 B;  4X65 I;  4X64 E;  4JI0 E;  2UXC E;  5LL6 R;  3U1K A;  4UTG A;  3M7N D;  4LF4 I;  1XMO I;  1S16 A;  4IS9 A;  4MU4 A;  5A2Q Q;  4LF7 I;  1HNW E;  2IOP A;  2WNR A;  4GKK E;  2UXC I;  1HR0 I;  1H72 C;  2PO0 A;  3CWV A;  5JEA F;  4LFB I;  1WUU A;  4NXN E;  5ELW A;  2BM1 A;  1NHI A;  5LMU I;  3PYE A;  2WP8 A;  3PRY A;  3T1H E;  4HYM A;  2ZBK B;  4DV7 I;  2C38 B;  4JI6 I;  4USK A;  2IER A;  1XNQ E;  2CVE A;  4K0K I;  1ZM3 A;  3NZK A;  1ELO A;  4LF6 I;  5A2Q C;  3Q6M A;  3T1Y E;  4B3S E;  1H7U A;  1FJG I;  1RR9 A;  3PS1 A;  2CG9 A;  2VQE I;  2HK2 A;  4NBQ A;  4JI7 E;  4IZK A;  4OX9 E;  1N0U A;  5K36 A;  1Y4S A;  1EA6 A;  1XXE A;  5JEA B;  2NN6 E;  3T1Y I;  2UUB I;  5FLX Q;  4YHH I;  4HAC A;  5C0X B;  2UXD I;  1K47 A;  3WU4 A;  1OYP A;  1B62 A;  1PKP A;  4GKJ I;  4DU8 A;  2JEB A;  2O1T A;  2Z5C B;  4FW6 A;  5DNX A;  2NN6 F;  3ZKB A;  1USV A;  2Z5C A;  1J5E I;  4PRX A;  4X66 E;  2UUA E;  4IFD E;  5EL9 A;  4JI8 I;  5C0X F;  1PVG A;  1FJG E;  3HUL A;  2BA0 D;  2JEB B;  2V34 A;  1BKN A;  3CDJ A;  4OO1 E;  2BA1 D;  2V2Z A;  3P76 A;  4UT4 A;  2JEA A;  2C39 B;  1Z0B A;  1U2R A;  4P7A A;  1KKH A;  3B78 A;  2V2V A;  2IOQ A;  4MU1 A;  4Z7Y A;  1N0V C;  2LJP A;  1IBK E;  3L7Z B;  1Z0V A;  4LPF A;  1USU A;  5DRQ A;  1DAR A;  1XNQ I;  4LF5 E;  3OTO I;  1Z0G A;  1B63 A;  4M1K A;  1NHJ A;  5IT9 Q;  1Z0C A;  4JI3 E;  4B3M E;  2E5L I;  2HKJ A;  4OO1 C;  2HHH I;  2ZM6 E;  3Q6N A;  2PO2 B;  2BR2 A;  5DRR A;  4DR5 E;  1IBL I;  4JI5 I;  4LCF A;  4OO1 B;  1IBM E;  4IFD D;  3J81 Q;  1OJ4 A;  1FNM A;  4IZJ A;  1E3H A;  2GQ0 A;  2ZIT A;  4MU3 A;  4DV0 E;  1HNZ I;  2UXB E;  4IZJ B;  4LF6 E;  4DV1 E;  4DR7 E;  4KHP I;  4P52 A;  4B3R E;  4BA1 B;  1Z5B A;  4QNJ A;  3LTO A;  4WUB A;  2UXB I;  3F0N A;  3JAM C;  1NHH A;  2J65 A;  3B4T A;  1N36 E;  4FW7 A;  2X36 A;  1MG7 A;  4DR3 I;  1Z59 A;  4DV5 I;  1EI1 A;  2F4V I;  3QT7 A;  4FWD A;  4LF7 E;  1HNW I;  5JEA E;  4ED4 A;  3HJC A;  2BA0 G;  5IWA I;  1N33 I;  4GKJ E;  4DV3 E;  4LOM A;  1IBK I;  4AID A;  2O1V A;  5C0X D;  4LF5 I;  4U3D A;  1UEK A;  5K36 E;  3M6A A;  4X64 I;  5C0X C;  2HKE A;  4OX9 I;  4DV3 I;  2A2D A;  4DR6 I;  2J7K A;  1XNR E;  3PYF A;  3M85 D;  2DEJ A;  3PS2 A;  2PO1 A;  2AJ4 A;  4FW9 A;  3J80 Q;  2ZM6 I;  5GMD A;  5BR8 E;  2C38 A;  4J3D A;  2R3V A;  5LMN E;  1HR0 E;  3DD6 A;  3U1Y A;  1N36 I;  5FWK A;  4BA2 A;  5JEA A;  4YY3 E;  1ZM4 A;  4DR3 E;  2Z5B A;  1XNR I;  3LPS A;  4B3S I;  4HAC B;  5GME A;  4MYU A;  3ZM7 A;  2UUC E;  4GQU A;  2UU9 E;  3P3C A;  3UHM A;  4B3R I;  4LCG A;  4DPT A;  2PNM A;  3K1J A;  4JI4 I;  1I94 E;  2UXD E;  2NN6 D;  1FWL A;  3PYD A;  4OKG A;  4PRV A;  3WU5 A;  4LFC I;  4EMD A;  4JI2 E;  5K36 D;  3P3E A;  3ZKD A;  4FW3 A;  5DNL A;  4LFB E;  4DV5 E;  2V2Q A;  4JI4 E;  2E1R A;  2HFS A;  1PIE A;  3P06 A;  1N32 E;  2X7I A;  2GO4 A;  1UDS A;  3H4L A;  1Z5A A;  2WW4 A;  4MYT A;  3ZZU A;  4DV7 E;  2UUB E;  1ZM9 A;  4X62 I;  4DR1 E;  1H74 A;  4K0K E;  4DXL A;  3PS3 A;  1P42 A;  4FWH A;  1VI7 A;  4OO1 F;  1Z5C A;  4XTJ A;  4JI1 I;  4JI5 E;  4OO1 D;  1FI4 A;  1ZXM A;  4DV6 E;  3QT5 A;  2F4V E;  4IZJ D;  4DR2 E;  1H7S A;  3D4J A;  4DPU A;  5LMU E;  2UUA I;  2Z5B B;  1VIS A;  2PNZ A;  4JG4 A;  4JI8 E;  4USM A;  4N3O A;  4HY1 A;  2XEX A;  5C0X A;  4JI6 E;  1E3P A;  4QNK A;  1MX0 A;  2UUC I;  1S4E A;  2C37 B;  1XMQ E;  4BA1 A;  1UDN A;  4B3T E;  4OZE A;  4AQY E;  3Q1Q A;  4MDT A;  1IBM I;  1Z0W A;  2O3Z A;  4DR4 I;  2JE6 A;  4DV2 E;  4I3H A;  2PNL A;  4JYA I;  3B82 A;  3J7A G;  1Y6Z A;  1KIJ A;  4DUZ I;  4JI2 I;  4LFC E;  2E5L E;  4DPX A;  2VF3 A;  4LF4 E;  1Y4U A;  2Z5E A;  1UDQ A;  2CGE A;  4JYA E;  4FN5 A;  3M85 G;  4GKK I;  2UU9 I;  2JE6 B;  4LF8 E;  2VES A;  5JEA C;  3CDI A;  3J80 C;  2O1U A;  1Z0T A;  1HNX E;  5JEA D;  3OTO E;  4X62 E;  4DV0 I;  4Z7C A;  1HNZ E;  1FKA E;  3J7A M;  3P3G A;  3HKM A;  2OI2 A;  4ZVI A;  2Q2E B;  4LF8 I;  1N33 E;  4YY3 I;  1N34 I;  1Z0E A;  4NXM I;  5C0X E;  5K36 C;  1NZ0 A;  1OYS A;  1HK7 A;  2GO3 A;  2VQF I;  4DV2 I;  4MQY A;  2PNZ B;  2BM0 A; 
#chains in the Genus database with same CATH homology
 4QNJ A;  4QNK A;  4LPF A;  5DNX A;  5DNL A;  1RHY A;  4MU4 A;  2AE8 A;  4MU1 A;  5EL9 A;  5ELW A;  4MU3 A;  4GQU A;  4LOM A;  2F1D A;  4MU0 A;  5EKW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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