3NZKA

Structure of lpxc from yersinia enterocolitica complexed with chir090 inhibitor
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
298
structure length
298
Chain Sequence
MIKQRTLKRIVQATGVGLHTGKKVTLTMRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIIIEVNAPEVPIMDGSASPFVYLLLDAGIEELNSAKKFLRLKETVRVEDGDKWAELSPFNGFRLDFTIDFNHPAIDSSTQRYRLDFSADSFVRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDEAEMPLAFK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Structure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090 .
pubmed doi rcsb
source organism Yersinia enterocolitica
molecule tags Hydrolase
total genus 94
structure length 298
sequence length 298
chains with identical sequence B
ec nomenclature ec 3.5.1.33: N-acetylglucosamine deacetylase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3nzkA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3nzkA02
2GO4A 4OKGA 4OZEA 4MDTA 3NZKA 4U3BA 5DROA 4U3DA 2JT2A 5DRRA 2IESA 4LCHA 2IERA 4LCFA 2O3ZA 3P76A 3P3EA 2GO3A 1YHCA 2VESA 4LCGA 4FW6A 5DRQA 4FW4A 4IS9A 3PS1A 3PS3A 3P3CA 3U1YA 4MQYA 2J65A 5DRPA 1XXEA 3PS2A 1YH8A 4ISAA 4FW5A 3UHMA 4J3DA 4FW3A 4FW7A 3P3GA 1P42A
chains in the Genus database with same CATH superfamily
1A6FA 3LNUA 4DR6E 1QZRA 3LPSA 3GONA 2Z5BB 1N32I 4RPFA 4JI1E 4JI4I 3L7ZA 3P76A 5DNLA 3WU3A 2UU9E 1Z0GA 2F4VE 2LJPA 2PO1A 4USKA 4ZVIA 2IOPA 4YHHE 4DV7I 2UXDE 3PS1A 1D6TA 1Z0VA 2F1DA 3B4TA 2V2QA 2CVEA 2NN6F 4FW5A 2NN6C 2HFUA 1P42A 1FNMA 2NN6B 1FJGE 1EI1A 5A2QQ 1Z0BA 5JEAF 1Z5CA 1Y4UA 2WP8A 1XNRE 2NN6E 1I94I 3JAMC 4IFDD 2BR2A 5BR8E 2HK3A 5K36F 2UUCE 2C39A 2O1UA 1XMQI 2C37A 3PYFA 5K36C 2O1VA 5JEAE 5K36B 1NHHA 4JI3E 1N36I 1B63A 4DUYE 1HNXI 1XHKA 2HKEA 5GMEA 2DEIA 4B3SE 5K36E 2WNRB 1YH8A 4NXME 4LPFA 4USMA 3T1YE 1N32E 1XNQI 1H73A 1WUUA 3GMEA 4DUZI 2BM1A 4LF9E 2VF3A 3ZZUA 5IT9C 4GKKI 4PU9A 4FWHA 4DV7E 1FWKA 3WU5A 4B3RI 3B8HA 1J5EE 3P3EA 4YY3E 4BA1B 2PO0B 2UXBE 1PVGA 4DV2I 4JI2E 5IWAI 1ZM9A 5ELWA 3M85G 2UUBI 2Q2EB 4JI8E 3ZM7A 4URLA 5C0XA 2ZM6I 3QT8A 2X36A 4J3DA 4MU3A 4DPWA 4JYAI 4HY1A 3K1JA 4HYMA 3NZKA 3J7AG 4DPYA 4KQVA 4FWDA 4OX9E 4OO1F 3B78A 3J80C 1KIJA 4LCGA 3HJCA 2EFGA 3GCMA 2Z5BA 1XNQE 4B3TE 4JI1I 4OO1E 2UU9I 2F4VI 1UEKA 5LMUI 4DV6E 3T1HI 1N33E 1VI7A 3HKMA 2GO4A 1NHIA 2UXCE 4BA2B 1HNZE 4DV2E 4X66I 2JT2A 5DRRA 1N0UA 4B3ME 2NN6A 1UDOA 1MX0A 4KHPI 1FJGI 1BKNA 2CZ9A 3ZKDA 4MU0A 1XNRI 4HACB 2UUCI 1USVA 2XEXA 1NHJA 3PYEA 4DPTA 4AM3A 4LFBI 5K36A 2C38B 4LCFA 4JI3I 4DUYI 1ZM2A 4XTJA 2WNRA 4B3SI 2O1WA 1Z5AA 4N3OA 4NXMI 5L3JA 4GQUA 3M85D 1B62A 3T1YI 4JV5E 1Z0WA 5A2QC 5LMUE 3T1HE 4LF9I 1MG7A 2BA0D 3D4JA 4MQYA 1J5EI 1VISA 4YY3I 2V2VA 1IBLE 4BA1A 2PO0A 3QT7A 4DV4E 4DR5E 2UXBI 3UHMA 1N34E 1HR0I 4X66E 4JI2I 1Y4SA 1ZXMA 4KHPE 4U3BA 4JI8I 2PNLA 1PKPA 5JEAC 3LTOA 4NXNI 4LF5E 1UDSA 5JEAB 2PNMA 1Z5BA 2DEJA 4WUDA 3ZZTA 4FN5A 4LFBE 4X64E 4EMDA 1OYSA 3J7AM 4OX9I 4IS9A 3P3CA 1R6LA 4GKJI 4LOMA 5FLXQ 4B3TI 5EL9A 3M6AA 5C0XD 3CWVA 4DV6I 4DR7E 3Q6NA 5GMDA 4DV0E 2BV3A 4AIDA 1N33I 2BM0A 4LF4E 3PYDA 2Z5CB 4LF6I 3ZKBA 4DR3E 2UXCI 4WUCA 2VESA 4BA2A 4FW6A 1HNZI 1HR0E 1DARA 4QNJA 4X65E 1Y60A 4B3MI 2JEAA 4FWGA 4AQYE 4JI6E 4IZJB 4M1KA 1FWLA 1RR9A 4NXNE 1ZM4A 4HACA 4OKGA 2PO1B 4JI0I 3CDJA 3H4LA 1KVKA 2C38A 2X7IA 2CG9A 1FI4A 4OO1C 2UUAE 2NN6D 4OO1B 4GKJE 1OYRA 4UT4A 4QNKA 1OYPA 4LFAI 2WP8B 4JV5I 5JEAD 2V34A 4HXZA 4ED4A 4K0KE 4DU7A 4IZKB 3CDIA 4OZEA 4DV1E 3QT6A 4LF6E 2HKJA 2E5LE 4WUBA 3U1KA 5K36D 1N0VC 1OJ4A 1IBLI 3HULA 5DROA 4DR5I 4DV4I 4JI5E 1N34I 1UDQA 2A2DA 2O3ZA 5LL6R 1PIEA 2JE6B 4X62E 4LF7I 4IFDF 1Z0EA 4IFDC 5JEAA 4LF5I 4IFDB 1ELOA 1UDNA 4LFCE 3K17A 5DRPA 2VQEE 3OTOI 3WU6A 4JI0E 4MU1A 3Q1QA 4I3HA 1Z0TA 4X64I 3J81Q 2GS8A 3V2UC 4IFDE 3ZZ0A 4P52A 4MU4A 1H74A 4JG4A 4U3DA 2NPFA 5C0XF 1Y5YA 4P7AA 2O1TA 4IZJD 4DR2E 1HNWE 4LFAE 4UTGA 1FKAE 1XMOI 3Q6MA 4DR7I 2R3VA 4DV0I 3M7NG 4LF4I 2WW4A 2Z5CA 2IOQA 3P3GA 4DR3I 2PO2B 1E3HA 2J7KA 4X65I 4OO1D 1RHYA 4LF7E 2PNZB 4AQYI 4IZJA 4JI6I 1MU5A 2IESA 2VQFE 4LCHA 2IERA 3F0NA 2GO3A 5FLXC 4MYUA 3OTOE 1NZ0A 5DNXA 1K47A 1U2RA 1IBKI 2V2ZA 5DRQA 4AIMA 3H1CA 4DV3E 4ISAA 4DPUA 4DPXA 2Z5EA 4OO1A 2UUAI 3V5RA 2HHHE 4DR1I 4DR4I 2ZITA 5EKWA 3PYGA 4R1FA 3QT5A 1XMOE 2A2CA 4K0KI 1H72C 4IZKA 4PRXA 4DV1I 3KRNA 1YHCA 2E5LI 4DV5E 1Z59A 4LF8E 5LMNE 2AE8A 4JI5I 2JEBB 4FW4A 1RREA 4NBQA 2HFSA 3JAMQ 1KTVA 2JE6A 3WU4A 4X62I 2HK2A 4JI4E 2CGEA 3L7ZB 4IFDA 4LFCI 2VQEI 5FWKA 2BA1G 1IBKE 3M7ND 2AJ4A 4JI7I 3DD6A 1R6MA 1S16A 1KKHA 3PRYA 1HK7A 1IBMI 4DR1E 4DR4E 3U1YA 1USUA 4DR2I 1HNWI 1XXEA 5IT9Q 1I94E 2BR2B 2BA0G 3B82A 1XMQE 2C39B 4PRVA 2C37B 4Z7CA 1N36E 2PO2A 2V8PA 1HNXE 1H7SA 3J81C 4DR6I 4DXLA 3P06A 2PNZA 4MYTA 2VQFI 3PS3A 2R42A 2J65A 4DU8A 4DUZE 3PS2A 2OI2A 2ZBKB 4Z7YA 4FW9A 1EA6A 4GKKE 1H7UA 4YHHI 1Y6ZA 4FW7A 4B3RE 2UXDI 4JI7E 3J80Q 4MDTA 1ZM3A 4DV3I 5IWAE 1E3PA 1ZXNA 3K85A 1IBME 2HHHI 2UUBE 2JEAB 1Z0CA 5C0XC 5C0XB 2ZM6E 5BR8I 4JYAE 3GLLA 1S4EA 5C0XE 2BA1D 4DV5I 2E1RA 5LMNI 4LF8I 4FW3A 2GQ0A 2JEBA
chains in the Genus database with same CATH topology
2GO4A 4OKGA 4OZEA 4MDTA 3NZKA 4U3BA 5DROA 4U3DA 2JT2A 5DRRA 2IESA 4LCHA 2IERA 4LCFA 2O3ZA 3P76A 3P3EA 2GO3A 1YHCA 2VESA 4LCGA 4FW6A 5DRQA 4FW4A 4IS9A 3PS1A 3PS3A 3P3CA 3U1YA 4MQYA 2J65A 5DRPA 1XXEA 3PS2A 1YH8A 4ISAA 4FW5A 3UHMA 4J3DA 4FW3A 4FW7A 3P3GA 1P42A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GO4 A;  4OKG A;  4OZE A;  4MDT A;  3NZK A;  4U3B A;  5DRO A;  4U3D A;  2JT2 A;  5DRR A;  2IES A;  4LCH A;  2IER A;  4LCF A;  2O3Z A;  3P76 A;  3P3E A;  2GO3 A;  1YHC A;  2VES A;  4LCG A;  4FW6 A;  5DRQ A;  4FW4 A;  4IS9 A;  3PS1 A;  3PS3 A;  3P3C A;  3U1Y A;  4MQY A;  2J65 A;  5DRP A;  1XXE A;  3PS2 A;  1YH8 A;  4ISA A;  4FW5 A;  3UHM A;  4J3D A;  4FW3 A;  4FW7 A;  3P3G A;  1P42 A; 
#chains in the Genus database with same CATH topology
 1A6F A;  3LNU A;  4DR6 E;  1QZR A;  3LPS A;  3GON A;  2Z5B B;  1N32 I;  4RPF A;  4JI1 E;  4JI4 I;  3L7Z A;  3P76 A;  5DNL A;  3WU3 A;  2UU9 E;  1Z0G A;  2F4V E;  2LJP A;  2PO1 A;  4USK A;  4ZVI A;  2IOP A;  4YHH E;  4DV7 I;  2UXD E;  3PS1 A;  1D6T A;  1Z0V A;  2F1D A;  3B4T A;  2V2Q A;  2CVE A;  2NN6 F;  4FW5 A;  2NN6 C;  2HFU A;  1P42 A;  1FNM A;  2NN6 B;  1FJG E;  1EI1 A;  5A2Q Q;  1Z0B A;  5JEA F;  1Z5C A;  1Y4U A;  2WP8 A;  1XNR E;  2NN6 E;  1I94 I;  3JAM C;  4IFD D;  2BR2 A;  5BR8 E;  2HK3 A;  5K36 F;  2UUC E;  2C39 A;  2O1U A;  1XMQ I;  2C37 A;  3PYF A;  5K36 C;  2O1V A;  5JEA E;  5K36 B;  1NHH A;  4JI3 E;  1N36 I;  1B63 A;  4DUY E;  1HNX I;  1XHK A;  2HKE A;  5GME A;  2DEI A;  4B3S E;  5K36 E;  2WNR B;  1YH8 A;  4NXM E;  4LPF A;  4USM A;  3T1Y E;  1N32 E;  1XNQ I;  1H73 A;  1WUU A;  3GME A;  4DUZ I;  2BM1 A;  4LF9 E;  2VF3 A;  3ZZU A;  5IT9 C;  4GKK I;  4PU9 A;  4FWH A;  4DV7 E;  1FWK A;  3WU5 A;  4B3R I;  3B8H A;  1J5E E;  3P3E A;  4YY3 E;  4BA1 B;  2PO0 B;  2UXB E;  1PVG A;  4DV2 I;  4JI2 E;  5IWA I;  1ZM9 A;  5ELW A;  3M85 G;  2UUB I;  2Q2E B;  4JI8 E;  3ZM7 A;  4URL A;  5C0X A;  2ZM6 I;  3QT8 A;  2X36 A;  4J3D A;  4MU3 A;  4DPW A;  4JYA I;  4HY1 A;  3K1J A;  4HYM A;  3NZK A;  3J7A G;  4DPY A;  4KQV A;  4FWD A;  4OX9 E;  4OO1 F;  3B78 A;  3J80 C;  1KIJ A;  4LCG A;  3HJC A;  2EFG A;  3GCM A;  2Z5B A;  1XNQ E;  4B3T E;  4JI1 I;  4OO1 E;  2UU9 I;  2F4V I;  1UEK A;  5LMU I;  4DV6 E;  3T1H I;  1N33 E;  1VI7 A;  3HKM A;  2GO4 A;  1NHI A;  2UXC E;  4BA2 B;  1HNZ E;  4DV2 E;  4X66 I;  2JT2 A;  5DRR A;  1N0U A;  4B3M E;  2NN6 A;  1UDO A;  1MX0 A;  4KHP I;  1FJG I;  1BKN A;  2CZ9 A;  3ZKD A;  4MU0 A;  1XNR I;  4HAC B;  2UUC I;  1USV A;  2XEX A;  1NHJ A;  3PYE A;  4DPT A;  4AM3 A;  4LFB I;  5K36 A;  2C38 B;  4LCF A;  4JI3 I;  4DUY I;  1ZM2 A;  4XTJ A;  2WNR A;  4B3S I;  2O1W A;  1Z5A A;  4N3O A;  4NXM I;  5L3J A;  4GQU A;  3M85 D;  1B62 A;  3T1Y I;  4JV5 E;  1Z0W A;  5A2Q C;  5LMU E;  3T1H E;  4LF9 I;  1MG7 A;  2BA0 D;  3D4J A;  4MQY A;  1J5E I;  1VIS A;  4YY3 I;  2V2V A;  1IBL E;  4BA1 A;  2PO0 A;  3QT7 A;  4DV4 E;  4DR5 E;  2UXB I;  3UHM A;  1N34 E;  1HR0 I;  4X66 E;  4JI2 I;  1Y4S A;  1ZXM A;  4KHP E;  4U3B A;  4JI8 I;  2PNL A;  1PKP A;  5JEA C;  3LTO A;  4NXN I;  4LF5 E;  1UDS A;  5JEA B;  2PNM A;  1Z5B A;  2DEJ A;  4WUD A;  3ZZT A;  4FN5 A;  4LFB E;  4X64 E;  4EMD A;  1OYS A;  3J7A M;  4OX9 I;  4IS9 A;  3P3C A;  1R6L A;  4GKJ I;  4LOM A;  5FLX Q;  4B3T I;  5EL9 A;  3M6A A;  5C0X D;  3CWV A;  4DV6 I;  4DR7 E;  3Q6N A;  5GMD A;  4DV0 E;  2BV3 A;  4AID A;  1N33 I;  2BM0 A;  4LF4 E;  3PYD A;  2Z5C B;  4LF6 I;  3ZKB A;  4DR3 E;  2UXC I;  4WUC A;  2VES A;  4BA2 A;  4FW6 A;  1HNZ I;  1HR0 E;  1DAR A;  4QNJ A;  4X65 E;  1Y60 A;  4B3M I;  2JEA A;  4FWG A;  4AQY E;  4JI6 E;  4IZJ B;  4M1K A;  1FWL A;  1RR9 A;  4NXN E;  1ZM4 A;  4HAC A;  4OKG A;  2PO1 B;  4JI0 I;  3CDJ A;  3H4L A;  1KVK A;  2C38 A;  2X7I A;  2CG9 A;  1FI4 A;  4OO1 C;  2UUA E;  2NN6 D;  4OO1 B;  4GKJ E;  1OYR A;  4UT4 A;  4QNK A;  1OYP A;  4LFA I;  2WP8 B;  4JV5 I;  5JEA D;  2V34 A;  4HXZ A;  4ED4 A;  4K0K E;  4DU7 A;  4IZK B;  3CDI A;  4OZE A;  4DV1 E;  3QT6 A;  4LF6 E;  2HKJ A;  2E5L E;  4WUB A;  3U1K A;  5K36 D;  1N0V C;  1OJ4 A;  1IBL I;  3HUL A;  5DRO A;  4DR5 I;  4DV4 I;  4JI5 E;  1N34 I;  1UDQ A;  2A2D A;  2O3Z A;  5LL6 R;  1PIE A;  2JE6 B;  4X62 E;  4LF7 I;  4IFD F;  1Z0E A;  4IFD C;  5JEA A;  4LF5 I;  4IFD B;  1ELO A;  1UDN A;  4LFC E;  3K17 A;  5DRP A;  2VQE E;  3OTO I;  3WU6 A;  4JI0 E;  4MU1 A;  3Q1Q A;  4I3H A;  1Z0T A;  4X64 I;  3J81 Q;  2GS8 A;  3V2U C;  4IFD E;  3ZZ0 A;  4P52 A;  4MU4 A;  1H74 A;  4JG4 A;  4U3D A;  2NPF A;  5C0X F;  1Y5Y A;  4P7A A;  2O1T A;  4IZJ D;  4DR2 E;  1HNW E;  4LFA E;  4UTG A;  1FKA E;  1XMO I;  3Q6M A;  4DR7 I;  2R3V A;  4DV0 I;  3M7N G;  4LF4 I;  2WW4 A;  2Z5C A;  2IOQ A;  3P3G A;  4DR3 I;  2PO2 B;  1E3H A;  2J7K A;  4X65 I;  4OO1 D;  1RHY A;  4LF7 E;  2PNZ B;  4AQY I;  4IZJ A;  4JI6 I;  1MU5 A;  2IES A;  2VQF E;  4LCH A;  2IER A;  3F0N A;  2GO3 A;  5FLX C;  4MYU A;  3OTO E;  1NZ0 A;  5DNX A;  1K47 A;  1U2R A;  1IBK I;  2V2Z A;  5DRQ A;  4AIM A;  3H1C A;  4DV3 E;  4ISA A;  4DPU A;  4DPX A;  2Z5E A;  4OO1 A;  2UUA I;  3V5R A;  2HHH E;  4DR1 I;  4DR4 I;  2ZIT A;  5EKW A;  3PYG A;  4R1F A;  3QT5 A;  1XMO E;  2A2C A;  4K0K I;  1H72 C;  4IZK A;  4PRX A;  4DV1 I;  3KRN A;  1YHC A;  2E5L I;  4DV5 E;  1Z59 A;  4LF8 E;  5LMN E;  2AE8 A;  4JI5 I;  2JEB B;  4FW4 A;  1RRE A;  4NBQ A;  2HFS A;  3JAM Q;  1KTV A;  2JE6 A;  3WU4 A;  4X62 I;  2HK2 A;  4JI4 E;  2CGE A;  3L7Z B;  4IFD A;  4LFC I;  2VQE I;  5FWK A;  2BA1 G;  1IBK E;  3M7N D;  2AJ4 A;  4JI7 I;  3DD6 A;  1R6M A;  1S16 A;  1KKH A;  3PRY A;  1HK7 A;  1IBM I;  4DR1 E;  4DR4 E;  3U1Y A;  1USU A;  4DR2 I;  1HNW I;  1XXE A;  5IT9 Q;  1I94 E;  2BR2 B;  2BA0 G;  3B82 A;  1XMQ E;  2C39 B;  4PRV A;  2C37 B;  4Z7C A;  1N36 E;  2PO2 A;  2V8P A;  1HNX E;  1H7S A;  3J81 C;  4DR6 I;  4DXL A;  3P06 A;  2PNZ A;  4MYT A;  2VQF I;  3PS3 A;  2R42 A;  2J65 A;  4DU8 A;  4DUZ E;  3PS2 A;  2OI2 A;  2ZBK B;  4Z7Y A;  4FW9 A;  1EA6 A;  4GKK E;  1H7U A;  4YHH I;  1Y6Z A;  4FW7 A;  4B3R E;  2UXD I;  4JI7 E;  3J80 Q;  4MDT A;  1ZM3 A;  4DV3 I;  5IWA E;  1E3P A;  1ZXN A;  3K85 A;  1IBM E;  2HHH I;  2UUB E;  2JEA B;  1Z0C A;  5C0X C;  5C0X B;  2ZM6 E;  5BR8 I;  4JYA E;  3GLL A;  1S4E A;  5C0X E;  2BA1 D;  4DV5 I;  2E1R A;  5LMN I;  4LF8 I;  4FW3 A;  2GQ0 A;  2JEB A; 
#chains in the Genus database with same CATH homology
 2GO4 A;  4OKG A;  4OZE A;  4MDT A;  3NZK A;  4U3B A;  5DRO A;  4U3D A;  2JT2 A;  5DRR A;  2IES A;  4LCH A;  2IER A;  4LCF A;  2O3Z A;  3P76 A;  3P3E A;  2GO3 A;  1YHC A;  2VES A;  4LCG A;  4FW6 A;  5DRQ A;  4FW4 A;  4IS9 A;  3PS1 A;  3PS3 A;  3P3C A;  3U1Y A;  4MQY A;  2J65 A;  5DRP A;  1XXE A;  3PS2 A;  1YH8 A;  4ISA A;  4FW5 A;  3UHM A;  4J3D A;  4FW3 A;  4FW7 A;  3P3G A;  1P42 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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