3NZKA

Structure of lpxc from yersinia enterocolitica complexed with chir090 inhibitor
Total Genus 94
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
94
sequence length
298
structure length
298
Chain Sequence
MIKQRTLKRIVQATGVGLHTGKKVTLTMRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIIIEVNAPEVPIMDGSASPFVYLLLDAGIEELNSAKKFLRLKETVRVEDGDKWAELSPFNGFRLDFTIDFNHPAIDSSTQRYRLDFSADSFVRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDEAEMPLAFK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090 .
pubmed doi rcsb
source organism Yersinia enterocolitica
molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 94
structure length 298
sequence length 298
chains with identical sequence B
ec nomenclature ec 3.5.1.33: N-acetylglucosamine deacetylase.
pdb deposition date 2010-07-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3nzkA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3nzkA02
3P3EA 4LCFA 1XXEA 5DRRA 5DROA 2JT2A 4MQYA 1YH8A 4ISAA 2IESA 4IS9A 2J65A 4FW5A 4FW3A 4FW4A 2GO3A 2IERA 2VESA 5DRQA 1YHCA 2GO4A 5DRPA 3PS2A 3P3GA 4MDTA 3U1YA 4LCGA 4J3DA 4LCHA 4FW7A 4OKGA 3P76A 4FW6A 3PS3A 2O3ZA 3UHMA 3PS1A 4U3DA 4OZEA 4U3BA 3NZKA 1P42A 3P3CA
chains in the Genus database with same CATH superfamily
1NZ0A 5JEAB 1N33I 4QNKA 2HFUA 4ZVIA 3CWVA 3LNUA 4DXLA 1XNQI 3ZZUA 1IBKE 3M7NG 2WP8A 4JI7I 3L7ZB 5BR8I 3OTOE 5GMEA 4DV4I 3WU5A 4IFDD 3U1YA 3J80C 1MG7A 4LCHA 2UXCI 3H4LA 1ZM4A 3PS3A 1Z59A 2UXCE 4OO1A 1N36I 1HNWE 2C37B 1S4EA 4R1FA 2UUBE 4IFDC 1FWKA 1Z0CA 4DR2I 4AQYE 4WUDA 2BR2B 2J65A 4DU7A 4BA2B 1ELOA 2GQ0A 5DRQA 4DV5E 4IFDA 3T1YI 2C37A 4DV6I 4IFDE 4JI6I 4B3TE 2VF3A 2Z5EA 4LF8E 3J7AG 4OKGA 1UDOA 1IBMI 1VI7A 4DU8A 1FJGE 5LMNI 3GLLA 4X66E 1OJ4A 3F0NA 1N34I 1I94E 3M6AA 3M85D 2JT2A 4B3MI 2ZBKB 2V8PA 1VISA 2BA1G 2UUCI 4DR2E 4AQYI 2GO3A 3ZZTA 4IZKB 2DEIA 4DV0E 4JI6E 4J3DA 5JEAA 3LPSA 3M85G 1R6LA 2CVEA 1FJGI 2BA1D 4GKKI 4KQVA 3ZKBA 4HXZA 4ISAA 2IESA 4NXMI 2Z5CA 4JI7E 2IERA 1HR0E 2JEBA 4B3SI 3T1YE 5K36E 2UUAE 2CG9A 2O1WA 4NXNI 1U2RA 4KHPE 2HHHI 4LFAI 2LJPA 5IWAI 4LFBE 2HHHE 3U1KA 3WU3A 1N0VC 5DNXA 4YY3I 4WUBA 4JI4I 1ZM3A 2A2DA 3K85A 1HNXE 3B82A 3QT7A 1XNRI 4IS9A 4IZKA 3J81C 1IBLE 1Z0WA 4LF4I 2GO4A 1WUUA 5DRPA 1FKAE 2PO2A 4MYTA 5LMUI 2X36A 2JEAA 1XMOI 2PNZA 2GS8A 3Q6MA 1Z0BA 3B78A 4DR1I 4FW6A 4DR1E 2HKEA 1Y5YA 4K0KI 4LF7E 4K0KE 1NHHA 2AJ4A 4DV3I 1N32I 2WW4A 1EI1A 4B3RI 1NHJA 5EL9A 2UUCE 4IFDB 2PO0B 1YHCA 3GMEA 3M7ND 3CDJA 1A6FA 2UU9I 3B8HA 1Z0VA 4FW7A 4JI4E 1IBLI 4LF4E 2PO0A 4LFAE 3Q6NA 4JI8E 3HULA 3PS1A 2BR2A 1UDSA 2UUAI 1S16A 1ZXMA 3ZZ0A 3CDIA 3L7ZA 4HACA 3T1HE 4YY3E 4JG4A 2Z5BA 3PYFA 2UU9E 1Y4SA 2JEAB 3LTOA 4OO1D 4LF9E 1N34E 1I94I 2V2ZA 4OX9E 5IWAE 4AM3A 1Z0TA 4P7AA 1H72C 2VESA 1H7SA 2BA0D 4IZJB 2C39B 4B3RE 4KHPI 3ZM7A 5EKWA 3WU6A 2NN6E 1BKNA 3K17A 1PKPA 1XHKA 1XNRE 4NXME 3PYGA 4I3HA 2X7IA 3GONA 3P3EA 4QNJA 1HNZE 5LL6R 3OTOI 4P52A 1N32E 4JYAE 4FW9A 2UUBI 5LMUE 1H7UA 4MU4A 4OO1C 4X64E 1Z5BA 4LF5I 4FW3A 2JEBB 5JEAD 3PYEA 1HR0I 4B3SE 4B3TI 4IZJA 2IOQA 4LOMA 4LF6I 3V5RA 3D4JA 4JI8I 2F4VE 4DPWA 2XEXA 5JEAF 1P42A 2NN6C 1Z5CA 4YHHI 5DRRA 5DROA 2PNMA 1B63A 2HK3A 4UT4A 4FW5A 1OYSA 4FW4A 5A2QQ 5FLXQ 4DR3E 4DR7E 2NN6B 1USUA 4DV1I 4BA1A 2Z5BB 4B3ME 3H1CA 4DR6E 5GMDA 4USMA 4DR6I 3JAMQ 5A2QC 1Z0EA 2WNRA 4LF5E 4LCFA 3QT5A 5DNLA 5C0XD 3B4TA 4DV0I 1FWLA 2OI2A 4HACB 2PNLA 4IFDF 5JEAE 1RREA 4X65E 4DV7I 4DUYE 1XNQE 4DPXA 4LF6E 1RR9A 4YHHE 2BM1A 4AIMA 4M1KA 4FWHA 4Z7CA 2ZM6I 3T1HI 5K36B 2AE8A 2V34A 1OYRA 1H73A 4DV7E 4OO1F 2O1VA 4X64I 3K1JA 5FWKA 4U3BA 1N0UA 2WP8B 2UXBI 1E3HA 4FWGA 1UEKA 2A2CA 4FWDA 4MQYA 3KRNA 4OO1B 3PYDA 1Y60A 2DEJA 5C0XC 5JEAC 4DV5I 2JE6A 4DR3I 5C0XE 4DR7I 1HNZI 2HK2A 4X65I 3J7AM 3ZKDA 2HFSA 2V2VA 3QT8A 2O1UA 5C0XA 1N33E 2VQFI 3UHMA 2VQFE 1XMQI 1NHIA 2BV3A 4JI3I 1N36E 1HNWI 2C38B 2R42A 1ZM9A 1D6TA 1ZM2A 1R6MA 3PRYA 1EA6A 1DARA 1E3PA 1YH8A 2V2QA 3HKMA 1FNMA 1IBKI 4JI0I 2NN6D 4OO1E 4WUCA 4DV1E 4X66I 1UDNA 1QZRA 2UXBE 5K36D 3JAMC 3DD6A 2O1TA 3WU4A 4OZEA 4DV2E 3P3CA 2C39A 3Q1QA 2NN6F 1USVA 1B62A 1MU5A 1Z5AA 1KIJA 1XXEA 4DV3E 2ZM6E 4GKJI 1RHYA 3QT6A 4DR4I 4LPFA 1J5EE 3J81Q 2JE6B 2E5LE 5C0XB 5K36A 4NBQA 3HJCA 1FI4A 4UTGA 4NXNE 4EMDA 4DPUA 4HYMA 4IZJD 4LFCI 1Y6ZA 3GCMA 5L3JA 2VQEI 2UXDE 4FN5A 4HY1A 1PIEA 4JI5I 4DUZI 4BA2A 4N3OA 4JYAI 2WNRB 4DUZE 4LF9I 1ZXNA 4LFBI 2PO1B 2CZ9A 2BM0A 1KTVA 4JI1I 2ZITA 4JI3E 4JV5I 4JI1E 2J7KA 2F1DA 3PS2A 4PU9A 4DR4E 1HK7A 1HNXI 3V2UC 1XMOE 2E5LI 2F4VI 5ELWA 4DR5E 4JI2I 2EFGA 2PO1A 2CGEA 4RPFA 4JV5E 4JI0E 4Z7YA 4URLA 2IOPA 4DPYA 2PNZB 4BA1B 2NPFA 5K36C 5K36F 2PO2B 4MU3A 2VQEE 4DV2I 3J80Q 2HKJA 4USKA 2E1RA 4MU0A 4X62I 2NN6A 4MDTA 4JI5E 4LCGA 2Z5CB 4MU1A 1KVKA 3P76A 1J5EI 2O3ZA 2BA0G 1Z0GA 3P06A 3NZKA 1XMQE 4DV4E 5FLXC 4AIDA 5IT9C 4X62E 2C38A 5BR8E 4GKKE 1MX0A 4PRXA 2R3VA 1K47A 2UXDI 1IBME 4PRVA 4OX9I 1KKHA 4LFCE 4LF8I 4DPTA 1Y4UA 4XTJA 1UDQA 3P3GA 4GQUA 1H74A 4GKJE 2Q2EB 5LMNE 1OYPA 4ED4A 4MYUA 4DUYI 1PVGA 4DR5I 4JI2E 5IT9Q 4U3DA 5C0XF 4DV6E 4LF7I
chains in the Genus database with same CATH topology
3P3EA 4LCFA 1XXEA 5DRRA 5DROA 2JT2A 4MQYA 1YH8A 4ISAA 2IESA 4IS9A 2J65A 4FW5A 4FW3A 4FW4A 2GO3A 2IERA 2VESA 5DRQA 1YHCA 2GO4A 5DRPA 3PS2A 3P3GA 4MDTA 3U1YA 4LCGA 4J3DA 4LCHA 4FW7A 4OKGA 3P76A 4FW6A 3PS3A 2O3ZA 3UHMA 3PS1A 4U3DA 4OZEA 4U3BA 3NZKA 1P42A 3P3CA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3P3E A;  4LCF A;  1XXE A;  5DRR A;  5DRO A;  2JT2 A;  4MQY A;  1YH8 A;  4ISA A;  2IES A;  4IS9 A;  2J65 A;  4FW5 A;  4FW3 A;  4FW4 A;  2GO3 A;  2IER A;  2VES A;  5DRQ A;  1YHC A;  2GO4 A;  5DRP A;  3PS2 A;  3P3G A;  4MDT A;  3U1Y A;  4LCG A;  4J3D A;  4LCH A;  4FW7 A;  4OKG A;  3P76 A;  4FW6 A;  3PS3 A;  2O3Z A;  3UHM A;  3PS1 A;  4U3D A;  4OZE A;  4U3B A;  3NZK A;  1P42 A;  3P3C A; 
#chains in the Genus database with same CATH topology
 1NZ0 A;  5JEA B;  1N33 I;  4QNK A;  2HFU A;  4ZVI A;  3CWV A;  3LNU A;  4DXL A;  1XNQ I;  3ZZU A;  1IBK E;  3M7N G;  2WP8 A;  4JI7 I;  3L7Z B;  5BR8 I;  3OTO E;  5GME A;  4DV4 I;  3WU5 A;  4IFD D;  3U1Y A;  3J80 C;  1MG7 A;  4LCH A;  2UXC I;  3H4L A;  1ZM4 A;  3PS3 A;  1Z59 A;  2UXC E;  4OO1 A;  1N36 I;  1HNW E;  2C37 B;  1S4E A;  4R1F A;  2UUB E;  4IFD C;  1FWK A;  1Z0C A;  4DR2 I;  4AQY E;  4WUD A;  2BR2 B;  2J65 A;  4DU7 A;  4BA2 B;  1ELO A;  2GQ0 A;  5DRQ A;  4DV5 E;  4IFD A;  3T1Y I;  2C37 A;  4DV6 I;  4IFD E;  4JI6 I;  4B3T E;  2VF3 A;  2Z5E A;  4LF8 E;  3J7A G;  4OKG A;  1UDO A;  1IBM I;  1VI7 A;  4DU8 A;  1FJG E;  5LMN I;  3GLL A;  4X66 E;  1OJ4 A;  3F0N A;  1N34 I;  1I94 E;  3M6A A;  3M85 D;  2JT2 A;  4B3M I;  2ZBK B;  2V8P A;  1VIS A;  2BA1 G;  2UUC I;  4DR2 E;  4AQY I;  2GO3 A;  3ZZT A;  4IZK B;  2DEI A;  4DV0 E;  4JI6 E;  4J3D A;  5JEA A;  3LPS A;  3M85 G;  1R6L A;  2CVE A;  1FJG I;  2BA1 D;  4GKK I;  4KQV A;  3ZKB A;  4HXZ A;  4ISA A;  2IES A;  4NXM I;  2Z5C A;  4JI7 E;  2IER A;  1HR0 E;  2JEB A;  4B3S I;  3T1Y E;  5K36 E;  2UUA E;  2CG9 A;  2O1W A;  4NXN I;  1U2R A;  4KHP E;  2HHH I;  4LFA I;  2LJP A;  5IWA I;  4LFB E;  2HHH E;  3U1K A;  3WU3 A;  1N0V C;  5DNX A;  4YY3 I;  4WUB A;  4JI4 I;  1ZM3 A;  2A2D A;  3K85 A;  1HNX E;  3B82 A;  3QT7 A;  1XNR I;  4IS9 A;  4IZK A;  3J81 C;  1IBL E;  1Z0W A;  4LF4 I;  2GO4 A;  1WUU A;  5DRP A;  1FKA E;  2PO2 A;  4MYT A;  5LMU I;  2X36 A;  2JEA A;  1XMO I;  2PNZ A;  2GS8 A;  3Q6M A;  1Z0B A;  3B78 A;  4DR1 I;  4FW6 A;  4DR1 E;  2HKE A;  1Y5Y A;  4K0K I;  4LF7 E;  4K0K E;  1NHH A;  2AJ4 A;  4DV3 I;  1N32 I;  2WW4 A;  1EI1 A;  4B3R I;  1NHJ A;  5EL9 A;  2UUC E;  4IFD B;  2PO0 B;  1YHC A;  3GME A;  3M7N D;  3CDJ A;  1A6F A;  2UU9 I;  3B8H A;  1Z0V A;  4FW7 A;  4JI4 E;  1IBL I;  4LF4 E;  2PO0 A;  4LFA E;  3Q6N A;  4JI8 E;  3HUL A;  3PS1 A;  2BR2 A;  1UDS A;  2UUA I;  1S16 A;  1ZXM A;  3ZZ0 A;  3CDI A;  3L7Z A;  4HAC A;  3T1H E;  4YY3 E;  4JG4 A;  2Z5B A;  3PYF A;  2UU9 E;  1Y4S A;  2JEA B;  3LTO A;  4OO1 D;  4LF9 E;  1N34 E;  1I94 I;  2V2Z A;  4OX9 E;  5IWA E;  4AM3 A;  1Z0T A;  4P7A A;  1H72 C;  2VES A;  1H7S A;  2BA0 D;  4IZJ B;  2C39 B;  4B3R E;  4KHP I;  3ZM7 A;  5EKW A;  3WU6 A;  2NN6 E;  1BKN A;  3K17 A;  1PKP A;  1XHK A;  1XNR E;  4NXM E;  3PYG A;  4I3H A;  2X7I A;  3GON A;  3P3E A;  4QNJ A;  1HNZ E;  5LL6 R;  3OTO I;  4P52 A;  1N32 E;  4JYA E;  4FW9 A;  2UUB I;  5LMU E;  1H7U A;  4MU4 A;  4OO1 C;  4X64 E;  1Z5B A;  4LF5 I;  4FW3 A;  2JEB B;  5JEA D;  3PYE A;  1HR0 I;  4B3S E;  4B3T I;  4IZJ A;  2IOQ A;  4LOM A;  4LF6 I;  3V5R A;  3D4J A;  4JI8 I;  2F4V E;  4DPW A;  2XEX A;  5JEA F;  1P42 A;  2NN6 C;  1Z5C A;  4YHH I;  5DRR A;  5DRO A;  2PNM A;  1B63 A;  2HK3 A;  4UT4 A;  4FW5 A;  1OYS A;  4FW4 A;  5A2Q Q;  5FLX Q;  4DR3 E;  4DR7 E;  2NN6 B;  1USU A;  4DV1 I;  4BA1 A;  2Z5B B;  4B3M E;  3H1C A;  4DR6 E;  5GMD A;  4USM A;  4DR6 I;  3JAM Q;  5A2Q C;  1Z0E A;  2WNR A;  4LF5 E;  4LCF A;  3QT5 A;  5DNL A;  5C0X D;  3B4T A;  4DV0 I;  1FWL A;  2OI2 A;  4HAC B;  2PNL A;  4IFD F;  5JEA E;  1RRE A;  4X65 E;  4DV7 I;  4DUY E;  1XNQ E;  4DPX A;  4LF6 E;  1RR9 A;  4YHH E;  2BM1 A;  4AIM A;  4M1K A;  4FWH A;  4Z7C A;  2ZM6 I;  3T1H I;  5K36 B;  2AE8 A;  2V34 A;  1OYR A;  1H73 A;  4DV7 E;  4OO1 F;  2O1V A;  4X64 I;  3K1J A;  5FWK A;  4U3B A;  1N0U A;  2WP8 B;  2UXB I;  1E3H A;  4FWG A;  1UEK A;  2A2C A;  4FWD A;  4MQY A;  3KRN A;  4OO1 B;  3PYD A;  1Y60 A;  2DEJ A;  5C0X C;  5JEA C;  4DV5 I;  2JE6 A;  4DR3 I;  5C0X E;  4DR7 I;  1HNZ I;  2HK2 A;  4X65 I;  3J7A M;  3ZKD A;  2HFS A;  2V2V A;  3QT8 A;  2O1U A;  5C0X A;  1N33 E;  2VQF I;  3UHM A;  2VQF E;  1XMQ I;  1NHI A;  2BV3 A;  4JI3 I;  1N36 E;  1HNW I;  2C38 B;  2R42 A;  1ZM9 A;  1D6T A;  1ZM2 A;  1R6M A;  3PRY A;  1EA6 A;  1DAR A;  1E3P A;  1YH8 A;  2V2Q A;  3HKM A;  1FNM A;  1IBK I;  4JI0 I;  2NN6 D;  4OO1 E;  4WUC A;  4DV1 E;  4X66 I;  1UDN A;  1QZR A;  2UXB E;  5K36 D;  3JAM C;  3DD6 A;  2O1T A;  3WU4 A;  4OZE A;  4DV2 E;  3P3C A;  2C39 A;  3Q1Q A;  2NN6 F;  1USV A;  1B62 A;  1MU5 A;  1Z5A A;  1KIJ A;  1XXE A;  4DV3 E;  2ZM6 E;  4GKJ I;  1RHY A;  3QT6 A;  4DR4 I;  4LPF A;  1J5E E;  3J81 Q;  2JE6 B;  2E5L E;  5C0X B;  5K36 A;  4NBQ A;  3HJC A;  1FI4 A;  4UTG A;  4NXN E;  4EMD A;  4DPU A;  4HYM A;  4IZJ D;  4LFC I;  1Y6Z A;  3GCM A;  5L3J A;  2VQE I;  2UXD E;  4FN5 A;  4HY1 A;  1PIE A;  4JI5 I;  4DUZ I;  4BA2 A;  4N3O A;  4JYA I;  2WNR B;  4DUZ E;  4LF9 I;  1ZXN A;  4LFB I;  2PO1 B;  2CZ9 A;  2BM0 A;  1KTV A;  4JI1 I;  2ZIT A;  4JI3 E;  4JV5 I;  4JI1 E;  2J7K A;  2F1D A;  3PS2 A;  4PU9 A;  4DR4 E;  1HK7 A;  1HNX I;  3V2U C;  1XMO E;  2E5L I;  2F4V I;  5ELW A;  4DR5 E;  4JI2 I;  2EFG A;  2PO1 A;  2CGE A;  4RPF A;  4JV5 E;  4JI0 E;  4Z7Y A;  4URL A;  2IOP A;  4DPY A;  2PNZ B;  4BA1 B;  2NPF A;  5K36 C;  5K36 F;  2PO2 B;  4MU3 A;  2VQE E;  4DV2 I;  3J80 Q;  2HKJ A;  4USK A;  2E1R A;  4MU0 A;  4X62 I;  2NN6 A;  4MDT A;  4JI5 E;  4LCG A;  2Z5C B;  4MU1 A;  1KVK A;  3P76 A;  1J5E I;  2O3Z A;  2BA0 G;  1Z0G A;  3P06 A;  3NZK A;  1XMQ E;  4DV4 E;  5FLX C;  4AID A;  5IT9 C;  4X62 E;  2C38 A;  5BR8 E;  4GKK E;  1MX0 A;  4PRX A;  2R3V A;  1K47 A;  2UXD I;  1IBM E;  4PRV A;  4OX9 I;  1KKH A;  4LFC E;  4LF8 I;  4DPT A;  1Y4U A;  4XTJ A;  1UDQ A;  3P3G A;  4GQU A;  1H74 A;  4GKJ E;  2Q2E B;  5LMN E;  1OYP A;  4ED4 A;  4MYU A;  4DUY I;  1PVG A;  4DR5 I;  4JI2 E;  5IT9 Q;  4U3D A;  5C0X F;  4DV6 E;  4LF7 I; 
#chains in the Genus database with same CATH homology
 3P3E A;  4LCF A;  1XXE A;  5DRR A;  5DRO A;  2JT2 A;  4MQY A;  1YH8 A;  4ISA A;  2IES A;  4IS9 A;  2J65 A;  4FW5 A;  4FW3 A;  4FW4 A;  2GO3 A;  2IER A;  2VES A;  5DRQ A;  1YHC A;  2GO4 A;  5DRP A;  3PS2 A;  3P3G A;  4MDT A;  3U1Y A;  4LCG A;  4J3D A;  4LCH A;  4FW7 A;  4OKG A;  3P76 A;  4FW6 A;  3PS3 A;  2O3Z A;  3UHM A;  3PS1 A;  4U3D A;  4OZE A;  4U3B A;  3NZK A;  1P42 A;  3P3C A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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