4MU1A

The structure of wt a. thaliana igpd2 in complex with mn2+, imidazole, and sulfate at 1.5 a resolution
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
185
structure length
184
Chain Sequence
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLAHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
total genus 54
structure length 184
sequence length 185
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu1A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu1A02
4LOMA 5EKWA 4MU0A 2F1DA 5EL9A 4MU3A 4GQUA 4LPFA 5DNLA 4QNJA 1RHYA 2AE8A 4QNKA 5DNXA 4MU1A 4MU4A 5ELWA
chains in the Genus database with same CATH superfamily
5LMNE 4LFBE 4HACB 4BA2B 4X66I 2JEBB 4DPXA 2CGEA 2UU9I 4FW4A 2PO1A 5BR8E 1HNWE 1XNRI 2BR2B 3GONA 1Z5CA 3K17A 1HK7A 4NXNI 1N36I 2PO0B 5JEAB 2C37B 5C0XF 2WP8B 3ZZUA 1NZ0A 4UTGA 4DV6E 4X65I 4OO1E 2PNZB 2E5LE 3ZZ0A 4DR2I 2BM1A 4IZKA 5IT9C 5K36F 4I3HA 1WUUA 4FWDA 4DV1E 2V2QA 4LCHA 1ZXMA 4FW5A 1I94I 4FWHA 2OI2A 2PO1B 5LMUI 1Z0GA 2DEJA 1USVA 5DNLA 2V2VA 4ED4A 3JAMQ 1XNQI 4MYUA 2IOQA 4OX9E 5C0XA 1N32I 2GO3A 1XXEA 4JI1E 2O1UA 1S16A 4NBQA 4QNKA 4IZJB 1FJGI 2A2CA 4B3RE 2GS8A 3UHMA 1UDQA 4LPFA 2NN6C 4DV0I 4IZKB 2UXBE 5A2QQ 4DPWA 5K36A 2AJ4A 4MU3A 3PS1A 5FWKA 2F4VE 4PRXA 1IBME 4LF5E 4R1FA 4B3SE 1A6FA 2NN6B 1NHHA 2CZ9A 2HFSA 4YHHE 2VQEE 5DRRA 2O1WA 1J5EI 2E1RA 3J81C 1OJ4A 1N34I 2V8PA 2X7IA 2ZBKB 1Z0WA 4DV2E 4KHPE 4XTJA 4PRVA 3K1JA 4JI7E 2HHHE 4GKJE 2J65A 4EMDA 3WU4A 2BV3A 2WW4A 2V2ZA 3ZZTA 2V34A 5JEAF 4DR1E 1UDNA 3L7ZA 3P3GA 4KQVA 5DNXA 3QT6A 1MG7A 3T1YE 1Z0EA 3QT7A 3OTOE 2IOPA 2PNMA 2UXDE 3GCMA 4HACA 5GMDA 2UUBI 3WU5A 4N3OA 4JI8I 4B3TI 4DU7A 4BA2A 2AE8A 1PVGA 1D6TA 4DR6I 2JEBA 1N33E 1HR0I 2EFGA 3M85D 3Q6NA 4LF5I 4IFDE 5C0XD 4DXLA 2BR2A 4DV3I 4DR4E 4JI4I 1YH8A 4AIDA 1E3PA 1XMOI 1Y6ZA 2PO0A 1XMQI 4DPYA 4DV2I 1QZRA 3L7ZB 5K36D 2HHHI 4DUYI 4U3BA 3PYFA 2BM0A 4LF9E 4P52A 1B62A 4JV5I 2R3VA 4LCGA 5EKWA 1H74A 4OO1B 4JI5I 3T1YI 1HNXE 4OZEA 2DEIA 1KKHA 1N0UA 4AQYE 4DV5E 1KIJA 1OYPA 2PNLA 2GQ0A 1H7UA 2NN6F 1FWKA 2HFUA 3T1HE 4DU8A 3J7AG 4JI6I 4GKKE 3PYDA 1Z5AA 4JYAE 4LF8I 1Y5YA 2UUCI 2UXCI 2BA0D 4DR4I 4DR3I 1ZM9A 1VI7A 3ZKDA 2X36A 4IZJA 1XHKA 4YY3E 4FW9A 4MYTA 3ZKBA 1Y60A 3HKMA 4QNJA 4WUDA 4ZVIA 4LF4E 5LMNI 5LL6R 4LFBI 2Q2EB 4HY1A 3V5RA 2NN6A 2VQFE 1PIEA 1Z0BA 5DROA 1P42A 1IBLE 4LF7E 1HNZE 5BR8I 1HNWI 4X64E 1IBKE 3J7AM 5JEAD 2GO4A 4U3DA 1FKAE 4FW7A 4FW6A 3P06A 4DPUA 1FI4A 4LFCE 5JEAE 4DV6I 2C39B 2HKJA 3B4TA 2E5LI 3U1KA 4ISAA 4AIMA 4P7AA 4DV1I 4IFDC 4DR7E 4OO1F 4LF4I 3H1CA 2UUAE 3JAMC 1H73A 2O1VA 2VQFI 4K0KE 2CG9A 2BA1D 4LF6E 3CDJA 4LF7I 4OX9I 4IFDB 2BA0G 5C0XC 2LJPA 4IZJD 3Q6MA 3B78A 4HXZA 4JI1I 3J80Q 3CDIA 1Z0TA 4JI2E 1U2RA 1ZM2A 4NXME 4B3RI 1RREA 2HKEA 1R6LA 5A2QC 2UXBI 5K36C 4LOMA 4DV4E 3GMEA 5IWAE 4JI3E 4OO1A 5FLXQ 2NN6D 2F4VI 1IBMI 4JI0E 3B8HA 3P3CA 1VISA 2F1DA 1E3HA 1EA6A 4PU9A 4B3SI 3U1YA 4Z7YA 2PO2A 2JEAB 4YHHI 2VQEI 3LTOA 1Z0CA 3F0NA 1YHCA 1N0VC 3NZKA 3PS3A 4KHPI 2UU9E 5C0XE 2JT2A 1MX0A 1S4EA 1XNRE 4MDTA 4JI7I 3DD6A 4GKJI 4MU0A 3PRYA 4RPFA 5EL9A 4DR1I 4M1KA 4BA1A 1ZXNA 4UT4A 5K36E 1FNMA 1USUA 3OTOI 4MU1A 2UXDI 1Y4SA 4X65E 2PO2B 3QT8A 2O3ZA 3PYEA 4DR2E 5DRPA 2CVEA 4JI0I 4AM3A 1FWLA 1ZM3A 4MQYA 4DR5E 1N33I 5IT9Q 4HYMA 2J7KA 2JE6A 2C38B 5LMUE 1NHJA 1H72C 4X62E 1XNQE 2WNRB 2HK3A 1H7SA 5JEAC 4IFDF 4WUCA 4BA1B 3PS2A 1N32E 1B63A 1NHIA 2C39A 4LF9I 4OO1D 1FJGE 3V2UC 4J3DA 1KVKA 4DV0E 3GLLA 3M85G 1HNXI 2Z5BB 2ZM6E 2IERA 4DUZE 3K85A 4AQYI 2JE6B 4DV5I 1Y4UA 3T1HI 3M7ND 1Z0VA 5DRQA 4B3ME 4DR5I 3LNUA 4GKKI 4IFDA 4JYAI 4FWGA 1J5EE 4FW3A 2IESA 4GQUA 3J81Q 1R6MA 1Z5BA 5GMEA 1N34E 4X62I 1UDOA 4YY3I 2HK2A 4LFAE 5L3JA 3WU6A 4JG4A 2R42A 3LPSA 4FN5A 3P76A 2Z5EA 1UEKA 2VESA 4DPTA 2JEAA 3ZM7A 2ZM6I 1ELOA 4DUZI 1IBLI 2UUBE 1OYRA 4JI8E 4B3TE 1HNZI 4X64I 4DR6E 1RHYA 1IBKI 4USMA 1HR0E 4B3MI 3KRNA 3P3EA 3Q1QA 1OYSA 2XEXA 4DV3E 4JI4E 2Z5CA 5C0XB 4LFCI 1XMOE 1XMQE 3HJCA 4OKGA 2NPFA 4LFAI 1UDSA 4DV7E 4DUYE 1ZM4A 1PKPA 3PYGA 4JV5E 5ELWA 5K36B 4DR7I 4LCFA 2UUAI 2NN6E 4X66E 4JI5E 3M7NG 1EI1A 3HULA 4IFDD 4K0KI 4LF6I 2C38A 3H4LA 1Z59A 4USKA 4WUBA 2WNRA 3QT5A 3J80C 3D4JA 2Z5CB 4JI6E 1N36E 4NXNE 1K47A 4JI2I 1MU5A 2VF3A 3WU3A 4LF8E 1KTVA 4NXMI 4IS9A 1BKNA 4Z7CA 2UUCE 2UXCE 1RR9A 3B82A 4DR3E 4URLA 2O1TA 5JEAA 2C37A 5FLXC 5IWAI 4DV4I 4JI3I 4MU4A 4OO1C 3M6AA 4DV7I 2Z5BA 2WP8A 1DARA 3CWVA 2BA1G 2A2DA 2ZITA 2PNZA 1I94E
chains in the Genus database with same CATH topology
4LOMA 5EKWA 4MU0A 2F1DA 5EL9A 4MU3A 4GQUA 4LPFA 5DNLA 4QNJA 1RHYA 2AE8A 4QNKA 5DNXA 4MU1A 4MU4A 5ELWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LOM A;  5EKW A;  4MU0 A;  2F1D A;  5EL9 A;  4MU3 A;  4GQU A;  4LPF A;  5DNL A;  4QNJ A;  1RHY A;  2AE8 A;  4QNK A;  5DNX A;  4MU1 A;  4MU4 A;  5ELW A; 
#chains in the Genus database with same CATH topology
 5LMN E;  4LFB E;  4HAC B;  4BA2 B;  4X66 I;  2JEB B;  4DPX A;  2CGE A;  2UU9 I;  4FW4 A;  2PO1 A;  5BR8 E;  1HNW E;  1XNR I;  2BR2 B;  3GON A;  1Z5C A;  3K17 A;  1HK7 A;  4NXN I;  1N36 I;  2PO0 B;  5JEA B;  2C37 B;  5C0X F;  2WP8 B;  3ZZU A;  1NZ0 A;  4UTG A;  4DV6 E;  4X65 I;  4OO1 E;  2PNZ B;  2E5L E;  3ZZ0 A;  4DR2 I;  2BM1 A;  4IZK A;  5IT9 C;  5K36 F;  4I3H A;  1WUU A;  4FWD A;  4DV1 E;  2V2Q A;  4LCH A;  1ZXM A;  4FW5 A;  1I94 I;  4FWH A;  2OI2 A;  2PO1 B;  5LMU I;  1Z0G A;  2DEJ A;  1USV A;  5DNL A;  2V2V A;  4ED4 A;  3JAM Q;  1XNQ I;  4MYU A;  2IOQ A;  4OX9 E;  5C0X A;  1N32 I;  2GO3 A;  1XXE A;  4JI1 E;  2O1U A;  1S16 A;  4NBQ A;  4QNK A;  4IZJ B;  1FJG I;  2A2C A;  4B3R E;  2GS8 A;  3UHM A;  1UDQ A;  4LPF A;  2NN6 C;  4DV0 I;  4IZK B;  2UXB E;  5A2Q Q;  4DPW A;  5K36 A;  2AJ4 A;  4MU3 A;  3PS1 A;  5FWK A;  2F4V E;  4PRX A;  1IBM E;  4LF5 E;  4R1F A;  4B3S E;  1A6F A;  2NN6 B;  1NHH A;  2CZ9 A;  2HFS A;  4YHH E;  2VQE E;  5DRR A;  2O1W A;  1J5E I;  2E1R A;  3J81 C;  1OJ4 A;  1N34 I;  2V8P A;  2X7I A;  2ZBK B;  1Z0W A;  4DV2 E;  4KHP E;  4XTJ A;  4PRV A;  3K1J A;  4JI7 E;  2HHH E;  4GKJ E;  2J65 A;  4EMD A;  3WU4 A;  2BV3 A;  2WW4 A;  2V2Z A;  3ZZT A;  2V34 A;  5JEA F;  4DR1 E;  1UDN A;  3L7Z A;  3P3G A;  4KQV A;  5DNX A;  3QT6 A;  1MG7 A;  3T1Y E;  1Z0E A;  3QT7 A;  3OTO E;  2IOP A;  2PNM A;  2UXD E;  3GCM A;  4HAC A;  5GMD A;  2UUB I;  3WU5 A;  4N3O A;  4JI8 I;  4B3T I;  4DU7 A;  4BA2 A;  2AE8 A;  1PVG A;  1D6T A;  4DR6 I;  2JEB A;  1N33 E;  1HR0 I;  2EFG A;  3M85 D;  3Q6N A;  4LF5 I;  4IFD E;  5C0X D;  4DXL A;  2BR2 A;  4DV3 I;  4DR4 E;  4JI4 I;  1YH8 A;  4AID A;  1E3P A;  1XMO I;  1Y6Z A;  2PO0 A;  1XMQ I;  4DPY A;  4DV2 I;  1QZR A;  3L7Z B;  5K36 D;  2HHH I;  4DUY I;  4U3B A;  3PYF A;  2BM0 A;  4LF9 E;  4P52 A;  1B62 A;  4JV5 I;  2R3V A;  4LCG A;  5EKW A;  1H74 A;  4OO1 B;  4JI5 I;  3T1Y I;  1HNX E;  4OZE A;  2DEI A;  1KKH A;  1N0U A;  4AQY E;  4DV5 E;  1KIJ A;  1OYP A;  2PNL A;  2GQ0 A;  1H7U A;  2NN6 F;  1FWK A;  2HFU A;  3T1H E;  4DU8 A;  3J7A G;  4JI6 I;  4GKK E;  3PYD A;  1Z5A A;  4JYA E;  4LF8 I;  1Y5Y A;  2UUC I;  2UXC I;  2BA0 D;  4DR4 I;  4DR3 I;  1ZM9 A;  1VI7 A;  3ZKD A;  2X36 A;  4IZJ A;  1XHK A;  4YY3 E;  4FW9 A;  4MYT A;  3ZKB A;  1Y60 A;  3HKM A;  4QNJ A;  4WUD A;  4ZVI A;  4LF4 E;  5LMN I;  5LL6 R;  4LFB I;  2Q2E B;  4HY1 A;  3V5R A;  2NN6 A;  2VQF E;  1PIE A;  1Z0B A;  5DRO A;  1P42 A;  1IBL E;  4LF7 E;  1HNZ E;  5BR8 I;  1HNW I;  4X64 E;  1IBK E;  3J7A M;  5JEA D;  2GO4 A;  4U3D A;  1FKA E;  4FW7 A;  4FW6 A;  3P06 A;  4DPU A;  1FI4 A;  4LFC E;  5JEA E;  4DV6 I;  2C39 B;  2HKJ A;  3B4T A;  2E5L I;  3U1K A;  4ISA A;  4AIM A;  4P7A A;  4DV1 I;  4IFD C;  4DR7 E;  4OO1 F;  4LF4 I;  3H1C A;  2UUA E;  3JAM C;  1H73 A;  2O1V A;  2VQF I;  4K0K E;  2CG9 A;  2BA1 D;  4LF6 E;  3CDJ A;  4LF7 I;  4OX9 I;  4IFD B;  2BA0 G;  5C0X C;  2LJP A;  4IZJ D;  3Q6M A;  3B78 A;  4HXZ A;  4JI1 I;  3J80 Q;  3CDI A;  1Z0T A;  4JI2 E;  1U2R A;  1ZM2 A;  4NXM E;  4B3R I;  1RRE A;  2HKE A;  1R6L A;  5A2Q C;  2UXB I;  5K36 C;  4LOM A;  4DV4 E;  3GME A;  5IWA E;  4JI3 E;  4OO1 A;  5FLX Q;  2NN6 D;  2F4V I;  1IBM I;  4JI0 E;  3B8H A;  3P3C A;  1VIS A;  2F1D A;  1E3H A;  1EA6 A;  4PU9 A;  4B3S I;  3U1Y A;  4Z7Y A;  2PO2 A;  2JEA B;  4YHH I;  2VQE I;  3LTO A;  1Z0C A;  3F0N A;  1YHC A;  1N0V C;  3NZK A;  3PS3 A;  4KHP I;  2UU9 E;  5C0X E;  2JT2 A;  1MX0 A;  1S4E A;  1XNR E;  4MDT A;  4JI7 I;  3DD6 A;  4GKJ I;  4MU0 A;  3PRY A;  4RPF A;  5EL9 A;  4DR1 I;  4M1K A;  4BA1 A;  1ZXN A;  4UT4 A;  5K36 E;  1FNM A;  1USU A;  3OTO I;  4MU1 A;  2UXD I;  1Y4S A;  4X65 E;  2PO2 B;  3QT8 A;  2O3Z A;  3PYE A;  4DR2 E;  5DRP A;  2CVE A;  4JI0 I;  4AM3 A;  1FWL A;  1ZM3 A;  4MQY A;  4DR5 E;  1N33 I;  5IT9 Q;  4HYM A;  2J7K A;  2JE6 A;  2C38 B;  5LMU E;  1NHJ A;  1H72 C;  4X62 E;  1XNQ E;  2WNR B;  2HK3 A;  1H7S A;  5JEA C;  4IFD F;  4WUC A;  4BA1 B;  3PS2 A;  1N32 E;  1B63 A;  1NHI A;  2C39 A;  4LF9 I;  4OO1 D;  1FJG E;  3V2U C;  4J3D A;  1KVK A;  4DV0 E;  3GLL A;  3M85 G;  1HNX I;  2Z5B B;  2ZM6 E;  2IER A;  4DUZ E;  3K85 A;  4AQY I;  2JE6 B;  4DV5 I;  1Y4U A;  3T1H I;  3M7N D;  1Z0V A;  5DRQ A;  4B3M E;  4DR5 I;  3LNU A;  4GKK I;  4IFD A;  4JYA I;  4FWG A;  1J5E E;  4FW3 A;  2IES A;  4GQU A;  3J81 Q;  1R6M A;  1Z5B A;  5GME A;  1N34 E;  4X62 I;  1UDO A;  4YY3 I;  2HK2 A;  4LFA E;  5L3J A;  3WU6 A;  4JG4 A;  2R42 A;  3LPS A;  4FN5 A;  3P76 A;  2Z5E A;  1UEK A;  2VES A;  4DPT A;  2JEA A;  3ZM7 A;  2ZM6 I;  1ELO A;  4DUZ I;  1IBL I;  2UUB E;  1OYR A;  4JI8 E;  4B3T E;  1HNZ I;  4X64 I;  4DR6 E;  1RHY A;  1IBK I;  4USM A;  1HR0 E;  4B3M I;  3KRN A;  3P3E A;  3Q1Q A;  1OYS A;  2XEX A;  4DV3 E;  4JI4 E;  2Z5C A;  5C0X B;  4LFC I;  1XMO E;  1XMQ E;  3HJC A;  4OKG A;  2NPF A;  4LFA I;  1UDS A;  4DV7 E;  4DUY E;  1ZM4 A;  1PKP A;  3PYG A;  4JV5 E;  5ELW A;  5K36 B;  4DR7 I;  4LCF A;  2UUA I;  2NN6 E;  4X66 E;  4JI5 E;  3M7N G;  1EI1 A;  3HUL A;  4IFD D;  4K0K I;  4LF6 I;  2C38 A;  3H4L A;  1Z59 A;  4USK A;  4WUB A;  2WNR A;  3QT5 A;  3J80 C;  3D4J A;  2Z5C B;  4JI6 E;  1N36 E;  4NXN E;  1K47 A;  4JI2 I;  1MU5 A;  2VF3 A;  3WU3 A;  4LF8 E;  1KTV A;  4NXM I;  4IS9 A;  1BKN A;  4Z7C A;  2UUC E;  2UXC E;  1RR9 A;  3B82 A;  4DR3 E;  4URL A;  2O1T A;  5JEA A;  2C37 A;  5FLX C;  5IWA I;  4DV4 I;  4JI3 I;  4MU4 A;  4OO1 C;  3M6A A;  4DV7 I;  2Z5B A;  2WP8 A;  1DAR A;  3CWV A;  2BA1 G;  2A2D A;  2ZIT A;  2PNZ A;  1I94 E; 
#chains in the Genus database with same CATH homology
 4LOM A;  5EKW A;  4MU0 A;  2F1D A;  5EL9 A;  4MU3 A;  4GQU A;  4LPF A;  5DNL A;  4QNJ A;  1RHY A;  2AE8 A;  4QNK A;  5DNX A;  4MU1 A;  4MU4 A;  5ELW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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