4MU1A

The structure of wt a. thaliana igpd2 in complex with mn2+, imidazole, and sulfate at 1.5 a resolution
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
185
structure length
184
Chain Sequence
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLAHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
total genus 54
structure length 184
sequence length 185
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu1A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu1A02
4QNJA 2AE8A 5EL9A 5DNLA 5DNXA 4MU3A 5EKWA 4LPFA 4LOMA 4MU0A 4MU1A 4QNKA 4MU4A 1RHYA 5ELWA 4GQUA 2F1DA
chains in the Genus database with same CATH superfamily
2IOPA 4USKA 1XHKA 2E5LI 2PO1A 3PYDA 2ZBKB 2ZM6E 1VI7A 3K1JA 4JI7E 4KHPE 1H74A 2ZITA 3WU6A 1S16A 1HR0E 4NXNI 3P76A 5C0XE 3PYFA 1H7UA 2V2VA 1Z0BA 1DARA 4HACB 1HNZI 2CVEA 2VQFI 4DPWA 2NN6D 4UT4A 4NBQA 1E3PA 2IESA 4MU4A 3D4JA 3Q6NA 1EA6A 4B3RE 2NN6C 3GMEA 5FWKA 4X65E 2JE6A 4DV1E 3GCMA 5L3JA 2OI2A 2VF3A 4DV7I 4JI5I 5LMUI 4DR6E 1N34E 4DV0I 1FI4A 4PRXA 2WNRA 1B63A 1ZM9A 4B3ME 1N32E 2O1UA 5K36A 2BA0D 4FWGA 4AQYE 4OO1F 1FJGI 1Z0GA 4OX9I 3F0NA 4DV5I 2C38B 3B8HA 2NN6B 1XNRE 1R6MA 2JE6B 4P52A 4LCHA 4FW3A 2WP8A 3LPSA 5JEAD 4DV2E 4B3TI 2JEAB 1RHYA 4JI3E 4DR1I 3J7AG 3B82A 3L7ZB 5JEAC 1FNMA 4LOMA 1Y4UA 4FW4A 5ELWA 1Y4SA 4BA1A 1ZXMA 5JEAE 4DPYA 1ZM3A 2C37B 2Z5BB 3M85D 4YHHI 2BM1A 5DROA 4JI6I 3M85G 5DNLA 4DUYE 4DV3I 4JI1I 2WW4A 4B3SE 3CWVA 2PO2B 4OO1A 1UDNA 5C0XF 3PYEA 4EMDA 1MG7A 4FW6A 4JI4E 5IWAI 2CGEA 2JT2A 4MU0A 3PS3A 5C0XD 2HK3A 2Z5EA 4USMA 4FWDA 4DU8A 4LFCE 2NN6A 2HKEA 3ZM7A 1XMQI 3LNUA 4DV4I 3K17A 2DEIA 4K0KI 3B78A 4DPXA 3J81Q 4LF7I 4X62E 1Z0CA 1USUA 3ZZUA 4J3DA 5C0XC 4LF4I 2UUCI 2C37A 4UTGA 4DR5I 1K47A 4JV5I 2AJ4A 2BA0G 2V2ZA 2UXBI 1Y5YA 1FWKA 2PO0B 2UUBE 4X66I 2R42A 3M6AA 2E1RA 4LF8E 2HFSA 2PNMA 4JI0E 1WUUA 4GKKI 3LTOA 1OJ4A 1IBLI 3NZKA 3ZKBA 5GMEA 5LMNE 3JAMQ 4IFDB 1Z0VA 5EL9A 2Q2EB 4IFDF 3WU4A 3T1HE 2GQ0A 4LFAE 5K36B 4LF9E 3T1YI 3ZZTA 4JI8I 4WUCA 2VQFE 3Q1QA 1I94E 4DR7I 4IFDD 4R1FA 3OTOI 3J80C 5DRPA 4XTJA 1KIJA 4HACA 1Z0TA 2XEXA 2BV3A 1N33I 4PRVA 5BR8I 2VQEE 2BA1G 4U3BA 1KVKA 3PS1A 2AE8A 1NHJA 2J7KA 2UXDI 4DR6I 1NHIA 2IERA 1Z5AA 5JEAA 2F4VI 2PO0A 3J80Q 4IZKB 4URLA 2CZ9A 2ZM6I 1MU5A 1D6TA 4JI7I 3P3CA 4KHPI 4X64I 2CG9A 1NHHA 5LL6R 1HR0I 5JEAF 1EI1A 1OYSA 4OX9E 2WP8B 5FLXC 1N0VC 1HNZE 4DUZE 4DV6I 1XNRI 4IZJB 3L7ZA 5GMDA 3QT6A 1XMOI 1YHCA 4LF5E 2BR2B 4DR2E 1OYRA 3B4TA 4NXMI 4ZVIA 2O1TA 4GKJE 2C38A 2NN6E 2PNZB 2C39B 1R6LA 1Y6ZA 5DRRA 3PRYA 4DV1I 3CDIA 1KKHA 1NZ0A 5EKWA 2EFGA 1N34I 4JI1E 1VISA 4BA1B 1RREA 1ZM4A 2HHHE 4I3HA 4AQYI 4JI4I 5IWAE 2J65A 1PIEA 1J5EI 4LCFA 2PO2A 4OO1B 1IBMI 4LF6E 3QT5A 4LFCI 2V34A 4QNKA 1XNQI 2VESA 4DV2I 4DPUA 2JEAA 4JI3I 4DR4E 2GS8A 2V2QA 2O1WA 2BA1D 4X62I 2PO1B 3U1KA 4FN5A 2UUCE 1HNWI 1UDOA 1Z5CA 4U3DA 1FWLA 4DPTA 4YHHE 4LFBI 3JAMC 4JI6E 4JI2I 1YH8A 4JV5E 1U2RA 4YY3I 2UU9E 5A2QQ 4JYAI 1N36I 4B3SI 1PKPA 2Z5CB 3H1CA 2UUAI 1HNXI 3GONA 2UXCE 4JI0I 5JEAB 3QT8A 2E5LE 5LMNI 4JG4A 4IZJD 1PVGA 2BM0A 4Z7YA 1MX0A 4NXNE 1XMQE 2F1DA 4JI8E 4MQYA 3DD6A 1Z59A 2O1VA 1I94I 1UDSA 3M7NG 3HKMA 2Z5CA 3P3EA 1IBKE 4ISAA 4LF4E 4DR3E 1USVA 4IS9A 4GQUA 1N33E 4RPFA 4B3RI 4FW9A 3WU3A 4Z7CA 3ZZ0A 4X65I 4X66E 1FKAE 1UEKA 3V2UC 4P7AA 4DV7E 4JI5E 5C0XB 1Z5BA 2IOQA 1BKNA 4MDTA 3P06A 3J7AM 1OYPA 1S4EA 1IBLE 1H73A 4M1KA 4B3MI 3CDJA 1N32I 4X64E 4DU7A 4IZJA 3T1HI 1ELOA 1FJGE 3T1YE 4QNJA 2GO4A 3Q6MA 4FW5A 4DV6E 4PU9A 4LPFA 3GLLA 4OO1C 3PS2A 4LF5I 4DR2I 2C39A 2NPFA 3OTOE 3HJCA 4KQVA 3J81C 2A2CA 4DR1E 1A6FA 2HK2A 4IFDE 2NN6F 4FW7A 2VQEI 1Y60A 2WNRB 2BR2A 2X36A 3V5RA 5FLXQ 2UXDE 2F4VE 4LCGA 5LMUE 3UHMA 4DV0E 4DV3E 5C0XA 2HHHI 4AM3A 1Z0WA 5DNXA 1J5EE 4DXLA 3M7ND 4DUZI 4AIMA 1IBME 4DV5E 4LF6I 1XMOE 2Z5BA 5A2QC 4OO1D 4DR4I 4B3TE 1B62A 4IZKA 3WU5A 4NXME 4GKJI 4K0KE 2JEBA 4LF7E 5K36D 3P3GA 4FWHA 4N3OA 3U1YA 1HNWE 4LFBE 1H7SA 4OZEA 5K36C 2V8PA 4JI2E 3ZKDA 4MU1A 1QZRA 4DR5E 1RR9A 4JYAE 4DUYI 5K36E 2A2DA 2HKJA 5K36F 3K85A 1UDQA 4MYTA 4ED4A 2UXBE 1Z0EA 2DEJA 2R3VA 2UUAE 2UUBI 2PNLA 4LF8I 2UXCI 2PNZA 4GKKE 1E3HA 2HFUA 4HXZA 2GO3A 5IT9Q 1KTVA 1P42A 5DRQA 4OKGA 3KRNA 4BA2B 1XNQE 4LFAI 4HY1A 4LF9I 2LJPA 4DV4E 1N0UA 4IFDC 4WUDA 1IBKI 4DR7E 4DR3I 2JEBB 1XXEA 5IT9C 4HYMA 1HK7A 2O3ZA 4WUBA 2X7IA 4MU3A 4OO1E 4YY3E 2UU9I 1ZXNA 1H72C 3HULA 3PYGA 1ZM2A 1N36E 5BR8E 4BA2A 3QT7A 4MYUA 3H4LA 4IFDA 4AIDA 1HNXE
chains in the Genus database with same CATH topology
4QNJA 2AE8A 5EL9A 5DNLA 5DNXA 4MU3A 5EKWA 4LPFA 4LOMA 4MU0A 4MU1A 4QNKA 4MU4A 1RHYA 5ELWA 4GQUA 2F1DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QNJ A;  2AE8 A;  5EL9 A;  5DNL A;  5DNX A;  4MU3 A;  5EKW A;  4LPF A;  4LOM A;  4MU0 A;  4MU1 A;  4QNK A;  4MU4 A;  1RHY A;  5ELW A;  4GQU A;  2F1D A; 
#chains in the Genus database with same CATH topology
 2IOP A;  4USK A;  1XHK A;  2E5L I;  2PO1 A;  3PYD A;  2ZBK B;  2ZM6 E;  1VI7 A;  3K1J A;  4JI7 E;  4KHP E;  1H74 A;  2ZIT A;  3WU6 A;  1S16 A;  1HR0 E;  4NXN I;  3P76 A;  5C0X E;  3PYF A;  1H7U A;  2V2V A;  1Z0B A;  1DAR A;  4HAC B;  1HNZ I;  2CVE A;  2VQF I;  4DPW A;  2NN6 D;  4UT4 A;  4NBQ A;  1E3P A;  2IES A;  4MU4 A;  3D4J A;  3Q6N A;  1EA6 A;  4B3R E;  2NN6 C;  3GME A;  5FWK A;  4X65 E;  2JE6 A;  4DV1 E;  3GCM A;  5L3J A;  2OI2 A;  2VF3 A;  4DV7 I;  4JI5 I;  5LMU I;  4DR6 E;  1N34 E;  4DV0 I;  1FI4 A;  4PRX A;  2WNR A;  1B63 A;  1ZM9 A;  4B3M E;  1N32 E;  2O1U A;  5K36 A;  2BA0 D;  4FWG A;  4AQY E;  4OO1 F;  1FJG I;  1Z0G A;  4OX9 I;  3F0N A;  4DV5 I;  2C38 B;  3B8H A;  2NN6 B;  1XNR E;  1R6M A;  2JE6 B;  4P52 A;  4LCH A;  4FW3 A;  2WP8 A;  3LPS A;  5JEA D;  4DV2 E;  4B3T I;  2JEA B;  1RHY A;  4JI3 E;  4DR1 I;  3J7A G;  3B82 A;  3L7Z B;  5JEA C;  1FNM A;  4LOM A;  1Y4U A;  4FW4 A;  5ELW A;  1Y4S A;  4BA1 A;  1ZXM A;  5JEA E;  4DPY A;  1ZM3 A;  2C37 B;  2Z5B B;  3M85 D;  4YHH I;  2BM1 A;  5DRO A;  4JI6 I;  3M85 G;  5DNL A;  4DUY E;  4DV3 I;  4JI1 I;  2WW4 A;  4B3S E;  3CWV A;  2PO2 B;  4OO1 A;  1UDN A;  5C0X F;  3PYE A;  4EMD A;  1MG7 A;  4FW6 A;  4JI4 E;  5IWA I;  2CGE A;  2JT2 A;  4MU0 A;  3PS3 A;  5C0X D;  2HK3 A;  2Z5E A;  4USM A;  4FWD A;  4DU8 A;  4LFC E;  2NN6 A;  2HKE A;  3ZM7 A;  1XMQ I;  3LNU A;  4DV4 I;  3K17 A;  2DEI A;  4K0K I;  3B78 A;  4DPX A;  3J81 Q;  4LF7 I;  4X62 E;  1Z0C A;  1USU A;  3ZZU A;  4J3D A;  5C0X C;  4LF4 I;  2UUC I;  2C37 A;  4UTG A;  4DR5 I;  1K47 A;  4JV5 I;  2AJ4 A;  2BA0 G;  2V2Z A;  2UXB I;  1Y5Y A;  1FWK A;  2PO0 B;  2UUB E;  4X66 I;  2R42 A;  3M6A A;  2E1R A;  4LF8 E;  2HFS A;  2PNM A;  4JI0 E;  1WUU A;  4GKK I;  3LTO A;  1OJ4 A;  1IBL I;  3NZK A;  3ZKB A;  5GME A;  5LMN E;  3JAM Q;  4IFD B;  1Z0V A;  5EL9 A;  2Q2E B;  4IFD F;  3WU4 A;  3T1H E;  2GQ0 A;  4LFA E;  5K36 B;  4LF9 E;  3T1Y I;  3ZZT A;  4JI8 I;  4WUC A;  2VQF E;  3Q1Q A;  1I94 E;  4DR7 I;  4IFD D;  4R1F A;  3OTO I;  3J80 C;  5DRP A;  4XTJ A;  1KIJ A;  4HAC A;  1Z0T A;  2XEX A;  2BV3 A;  1N33 I;  4PRV A;  5BR8 I;  2VQE E;  2BA1 G;  4U3B A;  1KVK A;  3PS1 A;  2AE8 A;  1NHJ A;  2J7K A;  2UXD I;  4DR6 I;  1NHI A;  2IER A;  1Z5A A;  5JEA A;  2F4V I;  2PO0 A;  3J80 Q;  4IZK B;  4URL A;  2CZ9 A;  2ZM6 I;  1MU5 A;  1D6T A;  4JI7 I;  3P3C A;  4KHP I;  4X64 I;  2CG9 A;  1NHH A;  5LL6 R;  1HR0 I;  5JEA F;  1EI1 A;  1OYS A;  4OX9 E;  2WP8 B;  5FLX C;  1N0V C;  1HNZ E;  4DUZ E;  4DV6 I;  1XNR I;  4IZJ B;  3L7Z A;  5GMD A;  3QT6 A;  1XMO I;  1YHC A;  4LF5 E;  2BR2 B;  4DR2 E;  1OYR A;  3B4T A;  4NXM I;  4ZVI A;  2O1T A;  4GKJ E;  2C38 A;  2NN6 E;  2PNZ B;  2C39 B;  1R6L A;  1Y6Z A;  5DRR A;  3PRY A;  4DV1 I;  3CDI A;  1KKH A;  1NZ0 A;  5EKW A;  2EFG A;  1N34 I;  4JI1 E;  1VIS A;  4BA1 B;  1RRE A;  1ZM4 A;  2HHH E;  4I3H A;  4AQY I;  4JI4 I;  5IWA E;  2J65 A;  1PIE A;  1J5E I;  4LCF A;  2PO2 A;  4OO1 B;  1IBM I;  4LF6 E;  3QT5 A;  4LFC I;  2V34 A;  4QNK A;  1XNQ I;  2VES A;  4DV2 I;  4DPU A;  2JEA A;  4JI3 I;  4DR4 E;  2GS8 A;  2V2Q A;  2O1W A;  2BA1 D;  4X62 I;  2PO1 B;  3U1K A;  4FN5 A;  2UUC E;  1HNW I;  1UDO A;  1Z5C A;  4U3D A;  1FWL A;  4DPT A;  4YHH E;  4LFB I;  3JAM C;  4JI6 E;  4JI2 I;  1YH8 A;  4JV5 E;  1U2R A;  4YY3 I;  2UU9 E;  5A2Q Q;  4JYA I;  1N36 I;  4B3S I;  1PKP A;  2Z5C B;  3H1C A;  2UUA I;  1HNX I;  3GON A;  2UXC E;  4JI0 I;  5JEA B;  3QT8 A;  2E5L E;  5LMN I;  4JG4 A;  4IZJ D;  1PVG A;  2BM0 A;  4Z7Y A;  1MX0 A;  4NXN E;  1XMQ E;  2F1D A;  4JI8 E;  4MQY A;  3DD6 A;  1Z59 A;  2O1V A;  1I94 I;  1UDS A;  3M7N G;  3HKM A;  2Z5C A;  3P3E A;  1IBK E;  4ISA A;  4LF4 E;  4DR3 E;  1USV A;  4IS9 A;  4GQU A;  1N33 E;  4RPF A;  4B3R I;  4FW9 A;  3WU3 A;  4Z7C A;  3ZZ0 A;  4X65 I;  4X66 E;  1FKA E;  1UEK A;  3V2U C;  4P7A A;  4DV7 E;  4JI5 E;  5C0X B;  1Z5B A;  2IOQ A;  1BKN A;  4MDT A;  3P06 A;  3J7A M;  1OYP A;  1S4E A;  1IBL E;  1H73 A;  4M1K A;  4B3M I;  3CDJ A;  1N32 I;  4X64 E;  4DU7 A;  4IZJ A;  3T1H I;  1ELO A;  1FJG E;  3T1Y E;  4QNJ A;  2GO4 A;  3Q6M A;  4FW5 A;  4DV6 E;  4PU9 A;  4LPF A;  3GLL A;  4OO1 C;  3PS2 A;  4LF5 I;  4DR2 I;  2C39 A;  2NPF A;  3OTO E;  3HJC A;  4KQV A;  3J81 C;  2A2C A;  4DR1 E;  1A6F A;  2HK2 A;  4IFD E;  2NN6 F;  4FW7 A;  2VQE I;  1Y60 A;  2WNR B;  2BR2 A;  2X36 A;  3V5R A;  5FLX Q;  2UXD E;  2F4V E;  4LCG A;  5LMU E;  3UHM A;  4DV0 E;  4DV3 E;  5C0X A;  2HHH I;  4AM3 A;  1Z0W A;  5DNX A;  1J5E E;  4DXL A;  3M7N D;  4DUZ I;  4AIM A;  1IBM E;  4DV5 E;  4LF6 I;  1XMO E;  2Z5B A;  5A2Q C;  4OO1 D;  4DR4 I;  4B3T E;  1B62 A;  4IZK A;  3WU5 A;  4NXM E;  4GKJ I;  4K0K E;  2JEB A;  4LF7 E;  5K36 D;  3P3G A;  4FWH A;  4N3O A;  3U1Y A;  1HNW E;  4LFB E;  1H7S A;  4OZE A;  5K36 C;  2V8P A;  4JI2 E;  3ZKD A;  4MU1 A;  1QZR A;  4DR5 E;  1RR9 A;  4JYA E;  4DUY I;  5K36 E;  2A2D A;  2HKJ A;  5K36 F;  3K85 A;  1UDQ A;  4MYT A;  4ED4 A;  2UXB E;  1Z0E A;  2DEJ A;  2R3V A;  2UUA E;  2UUB I;  2PNL A;  4LF8 I;  2UXC I;  2PNZ A;  4GKK E;  1E3H A;  2HFU A;  4HXZ A;  2GO3 A;  5IT9 Q;  1KTV A;  1P42 A;  5DRQ A;  4OKG A;  3KRN A;  4BA2 B;  1XNQ E;  4LFA I;  4HY1 A;  4LF9 I;  2LJP A;  4DV4 E;  1N0U A;  4IFD C;  4WUD A;  1IBK I;  4DR7 E;  4DR3 I;  2JEB B;  1XXE A;  5IT9 C;  4HYM A;  1HK7 A;  2O3Z A;  4WUB A;  2X7I A;  4MU3 A;  4OO1 E;  4YY3 E;  2UU9 I;  1ZXN A;  1H72 C;  3HUL A;  3PYG A;  1ZM2 A;  1N36 E;  5BR8 E;  4BA2 A;  3QT7 A;  4MYU A;  3H4L A;  4IFD A;  4AID A;  1HNX E; 
#chains in the Genus database with same CATH homology
 4QNJ A;  2AE8 A;  5EL9 A;  5DNL A;  5DNX A;  4MU3 A;  5EKW A;  4LPF A;  4LOM A;  4MU0 A;  4MU1 A;  4QNK A;  4MU4 A;  1RHY A;  5ELW A;  4GQU A;  2F1D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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