4MU1A

The structure of wt a. thaliana igpd2 in complex with mn2+, imidazole, and sulfate at 1.5 a resolution
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
185
structure length
184
Chain Sequence
SARIGEVKRETKETNVSVKINLDGHGVSDSSTGIPFLDHMLDQLAHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
total genus 54
structure length 184
sequence length 185
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu1A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu1A02
4MU1A 2F1DA 4MU4A 4QNKA 4LOMA 4GQUA 5EL9A 2AE8A 5EKWA 5DNLA 4MU0A 1RHYA 4QNJA 4MU3A 5ELWA 5DNXA 4LPFA
chains in the Genus database with same CATH superfamily
1Z5AA 2PO1A 4UTGA 4USMA 5DRPA 2JE6B 1XMOE 4DR6I 2WNRB 1RR9A 2UU9E 4KHPE 4NXNE 1MG7A 3H4LA 3P76A 3QT8A 2BM0A 4YY3I 4JYAE 2UUBI 2UUCE 1I94I 4DV7E 4FW6A 2HKJA 1N36E 4MU4A 1H72C 4LF7E 4DR7E 5K36B 4DR5E 4DV1E 1N33I 1Z5BA 4DPYA 1RREA 1FWKA 1H73A 4X64I 4J3DA 3LTOA 4DV6I 1N34I 2HHHE 1FJGE 3T1YI 3LPSA 3M7NG 3NZKA 4DV3I 4QNJA 1XXEA 1J5EE 4DPXA 4I3HA 4LF6I 2WP8B 2UXCE 5IWAI 4IZKB 5FWKA 3J7AM 1D6TA 4LPFA 4HACB 5A2QC 1FJGI 4B3RE 4LF6E 4USKA 1Z59A 4DR1I 4IZJD 3K17A 4DV4I 1IBKE 1OYSA 1EA6A 2LJPA 4WUDA 3ZZTA 5DRRA 1USUA 4LF4E 2O1UA 4JI7I 1E3PA 4HXZA 1HR0E 5IT9Q 1OYRA 3L7ZA 1WUUA 4JI5E 3M85G 4MYUA 4DR7I 5FLXQ 1HR0I 1NHHA 2HHHI 3B78A 4Z7YA 1HNWI 3H1CA 2PO2A 2NPFA 2VF3A 3P3EA 2JEBA 4YY3E 2CGEA 5JEAB 2IESA 1Z5CA 3M85D 4DV2E 5JEAC 1QZRA 2NN6C 4YHHI 2UXDE 1UDQA 4NXMI 4LFBE 4QNKA 4DR4E 1I94E 2CG9A 3P06A 2Q2EB 2EFGA 2C39B 5LL6R 2GQ0A 5IWAE 3HJCA 1IBKI 4X62I 4JI1E 4LOMA 5BR8E 2HK2A 4FN5A 5K36A 4M1KA 4DR1E 1ZM9A 3J81Q 2IOQA 2BR2A 5GMDA 4FW7A 4UT4A 2Z5BB 3U1YA 2PO0B 4OO1A 2Z5EA 2ZM6E 5BR8I 4OX9I 4MU0A 4LF8I 2UXCI 2Z5CB 5C0XC 4DV3E 1N33E 3T1HE 2C37B 2PO1B 5C0XB 2JE6A 1IBME 1Z0WA 4WUBA 2X36A 4JI2I 2WP8A 3PYGA 2BA1D 2ZBKB 4HYMA 5JEAD 4DV2I 2CVEA 3CDJA 3PRYA 2PNZA 3GONA 2UUAI 5DNLA 1FKAE 5K36D 2JEAB 4JI6I 4IFDC 2BA1G 3F0NA 4DR4I 2R3VA 4DUZI 4WUCA 4DPWA 4GKJE 1Y4SA 2IOPA 5K36E 4DU8A 4P7AA 4U3BA 2PNLA 4JYAI 3DD6A 2NN6E 2F1DA 4LCGA 5JEAE 4IFDE 2O1WA 3QT5A 4GKJI 5C0XF 3OTOI 1A6FA 4U3DA 4MYTA 1UDSA 4N3OA 4IZJA 4URLA 2PNMA 1MU5A 5L3JA 3QT7A 4BA2B 3WU5A 1R6LA 1ELOA 4DUYI 4DV4E 4OO1E 5JEAF 5LMNE 1USVA 4LF7I 4MU3A 4ISAA 4DV5E 3PS2A 3P3CA 2AJ4A 4IZKA 2ZM6I 4LFAE 3ZZ0A 2JEBB 4JI3I 3GLLA 4P52A 4LF4I 3PS3A 2HFUA 1U2RA 4OO1D 1NZ0A 4PRVA 4OZEA 2VQFE 2UXBI 1XNQI 3P3GA 4JI4E 5ELWA 1XMQE 2WW4A 1IBMI 2HK3A 2NN6B 4B3TI 4DXLA 4JI3E 1S4EA 3GCMA 4PU9A 1ZXMA 3Q6MA 3LNUA 3QT6A 3GMEA 1HNXE 1XNQE 5DROA 4LFCE 3J80C 4DR3I 1XNRE 3Q6NA 4ZVIA 5DNXA 1B62A 4JV5I 1DARA 5LMUE 2GO4A 1E3HA 1J5EI 1ZM4A 4DUYE 2UUAE 1MX0A 2O3ZA 3M6AA 3K85A 4LFAI 1Y6ZA 2V2ZA 4DU7A 1N36I 4X66I 4JI0I 4DR2E 2IERA 5LMNI 1EI1A 3T1HI 3ZZUA 2UUCI 1XHKA 2DEJA 5A2QQ 1FWLA 4RPFA 4DPUA 1Z0GA 1FI4A 5DRQA 2GO3A 1N0UA 2C38A 2J7KA 4BA1A 1RHYA 2O1TA 4IFDB 3B82A 2R42A 2X7IA 2V8PA 4X65I 4DR3E 1XNRI 4LFCI 2UU9I 1UDOA 2DEIA 5IT9C 1N32I 1Z0CA 4EMDA 2XEXA 4JI6E 4FWHA 4AIDA 1S16A 1XMQI 1Z0TA 1PVGA 4X64E 2F4VE 2E5LE 3HULA 2PNZB 4JI4I 1UEKA 4FWGA 2E1RA 3J80Q 4LCFA 1KTVA 1YH8A 3WU3A 2BM1A 4DR2I 1YHCA 4DV5I 4JI1I 4JI8I 1HNZE 4DV7I 1NHJA 1Z0VA 3PYFA 5JEAA 4HACA 2C39A 4DR5I 1HK7A 2A2CA 4HY1A 2OI2A 2BV3A 4R1FA 4JV5E 2J65A 3JAMC 4AQYI 2Z5BA 4B3SE 2PO0A 3B4TA 4OO1B 1IBLI 4NXME 4LFBI 1VI7A 4LF9E 2PO2B 1XMOI 2V2QA 1H7UA 4OO1C 2BR2B 3PYDA 2O1VA 4JI5I 3CWVA 1ZM3A 3J81C 4AIMA 3ZKBA 1HNXI 2HFSA 1H74A 4OX9E 4DUZE 1HNWE 5C0XD 2C37A 2NN6A 5GMEA 4MU1A 4OKGA 1NHIA 1Y4UA 2VQEE 3ZM7A 1FNMA 2WNRA 4JI2E 1Z0BA 1R6MA 4JI7E 2VQFI 2UXBE 4IFDA 4DV1I 4NBQA 3U1KA 3Q1QA 4B3TE 4B3MI 1OYPA 3V5RA 5K36C 4K0KE 4DV0E 4JI0E 1Y60A 3OTOE 4YHHE 2UXDI 1KKHA 2E5LI 4DV6E 1N34E 5K36F 4LF5E 3M7ND 3JAMQ 4IFDF 5FLXC 4XTJA 3UHMA 2BA0D 5C0XE 3D4JA 1PKPA 5C0XA 4LF9I 5LMUI 3K1JA 2CZ9A 4AQYE 4B3SI 4MQYA 4GKKI 1OJ4A 4DPTA 2V2VA 4Z7CA 4X65E 3WU4A 4PRXA 1N0VC 3KRNA 4KHPI 4IFDD 3T1YE 4KQVA 4X66E 3ZKDA 1ZXNA 1Y5YA 2C38B 4BA1B 2UUBE 4DR6E 4GQUA 2JEAA 1BKNA 2V34A 4GKKE 5EL9A 4NXNI 2NN6F 4LCHA 3CDIA 4JG4A 4JI8E 2VQEI 2NN6D 1UDNA 4FW3A 4B3ME 4K0KI 1KVKA 2HKEA 1K47A 2ZITA 4BA2A 4LF5I 4FW5A 1HNZI 4LF8E 4OO1F 3J7AG 1KIJA 4FWDA 1P42A 4IZJB 4DV0I 1Z0EA 2A2DA 1H7SA 4IS9A 2JT2A 3L7ZB 3B8HA 4FW4A 1VISA 1B63A 1PIEA 5EKWA 2AE8A 2BA0G 4FW9A 1N32E 4AM3A 1IBLE 2F4VI 2VESA 4X62E 3V2UC 3HKMA 2Z5CA 3WU6A 4B3RI 2GS8A 1ZM2A 4MDTA 3PS1A 3PYEA 4ED4A
chains in the Genus database with same CATH topology
4MU1A 2F1DA 4MU4A 4QNKA 4LOMA 4GQUA 5EL9A 2AE8A 5EKWA 5DNLA 4MU0A 1RHYA 4QNJA 4MU3A 5ELWA 5DNXA 4LPFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MU1 A;  2F1D A;  4MU4 A;  4QNK A;  4LOM A;  4GQU A;  5EL9 A;  2AE8 A;  5EKW A;  5DNL A;  4MU0 A;  1RHY A;  4QNJ A;  4MU3 A;  5ELW A;  5DNX A;  4LPF A; 
#chains in the Genus database with same CATH topology
 1Z5A A;  2PO1 A;  4UTG A;  4USM A;  5DRP A;  2JE6 B;  1XMO E;  4DR6 I;  2WNR B;  1RR9 A;  2UU9 E;  4KHP E;  4NXN E;  1MG7 A;  3H4L A;  3P76 A;  3QT8 A;  2BM0 A;  4YY3 I;  4JYA E;  2UUB I;  2UUC E;  1I94 I;  4DV7 E;  4FW6 A;  2HKJ A;  1N36 E;  4MU4 A;  1H72 C;  4LF7 E;  4DR7 E;  5K36 B;  4DR5 E;  4DV1 E;  1N33 I;  1Z5B A;  4DPY A;  1RRE A;  1FWK A;  1H73 A;  4X64 I;  4J3D A;  3LTO A;  4DV6 I;  1N34 I;  2HHH E;  1FJG E;  3T1Y I;  3LPS A;  3M7N G;  3NZK A;  4DV3 I;  4QNJ A;  1XXE A;  1J5E E;  4DPX A;  4I3H A;  4LF6 I;  2WP8 B;  2UXC E;  5IWA I;  4IZK B;  5FWK A;  3J7A M;  1D6T A;  4LPF A;  4HAC B;  5A2Q C;  1FJG I;  4B3R E;  4LF6 E;  4USK A;  1Z59 A;  4DR1 I;  4IZJ D;  3K17 A;  4DV4 I;  1IBK E;  1OYS A;  1EA6 A;  2LJP A;  4WUD A;  3ZZT A;  5DRR A;  1USU A;  4LF4 E;  2O1U A;  4JI7 I;  1E3P A;  4HXZ A;  1HR0 E;  5IT9 Q;  1OYR A;  3L7Z A;  1WUU A;  4JI5 E;  3M85 G;  4MYU A;  4DR7 I;  5FLX Q;  1HR0 I;  1NHH A;  2HHH I;  3B78 A;  4Z7Y A;  1HNW I;  3H1C A;  2PO2 A;  2NPF A;  2VF3 A;  3P3E A;  2JEB A;  4YY3 E;  2CGE A;  5JEA B;  2IES A;  1Z5C A;  3M85 D;  4DV2 E;  5JEA C;  1QZR A;  2NN6 C;  4YHH I;  2UXD E;  1UDQ A;  4NXM I;  4LFB E;  4QNK A;  4DR4 E;  1I94 E;  2CG9 A;  3P06 A;  2Q2E B;  2EFG A;  2C39 B;  5LL6 R;  2GQ0 A;  5IWA E;  3HJC A;  1IBK I;  4X62 I;  4JI1 E;  4LOM A;  5BR8 E;  2HK2 A;  4FN5 A;  5K36 A;  4M1K A;  4DR1 E;  1ZM9 A;  3J81 Q;  2IOQ A;  2BR2 A;  5GMD A;  4FW7 A;  4UT4 A;  2Z5B B;  3U1Y A;  2PO0 B;  4OO1 A;  2Z5E A;  2ZM6 E;  5BR8 I;  4OX9 I;  4MU0 A;  4LF8 I;  2UXC I;  2Z5C B;  5C0X C;  4DV3 E;  1N33 E;  3T1H E;  2C37 B;  2PO1 B;  5C0X B;  2JE6 A;  1IBM E;  1Z0W A;  4WUB A;  2X36 A;  4JI2 I;  2WP8 A;  3PYG A;  2BA1 D;  2ZBK B;  4HYM A;  5JEA D;  4DV2 I;  2CVE A;  3CDJ A;  3PRY A;  2PNZ A;  3GON A;  2UUA I;  5DNL A;  1FKA E;  5K36 D;  2JEA B;  4JI6 I;  4IFD C;  2BA1 G;  3F0N A;  4DR4 I;  2R3V A;  4DUZ I;  4WUC A;  4DPW A;  4GKJ E;  1Y4S A;  2IOP A;  5K36 E;  4DU8 A;  4P7A A;  4U3B A;  2PNL A;  4JYA I;  3DD6 A;  2NN6 E;  2F1D A;  4LCG A;  5JEA E;  4IFD E;  2O1W A;  3QT5 A;  4GKJ I;  5C0X F;  3OTO I;  1A6F A;  4U3D A;  4MYT A;  1UDS A;  4N3O A;  4IZJ A;  4URL A;  2PNM A;  1MU5 A;  5L3J A;  3QT7 A;  4BA2 B;  3WU5 A;  1R6L A;  1ELO A;  4DUY I;  4DV4 E;  4OO1 E;  5JEA F;  5LMN E;  1USV A;  4LF7 I;  4MU3 A;  4ISA A;  4DV5 E;  3PS2 A;  3P3C A;  2AJ4 A;  4IZK A;  2ZM6 I;  4LFA E;  3ZZ0 A;  2JEB B;  4JI3 I;  3GLL A;  4P52 A;  4LF4 I;  3PS3 A;  2HFU A;  1U2R A;  4OO1 D;  1NZ0 A;  4PRV A;  4OZE A;  2VQF E;  2UXB I;  1XNQ I;  3P3G A;  4JI4 E;  5ELW A;  1XMQ E;  2WW4 A;  1IBM I;  2HK3 A;  2NN6 B;  4B3T I;  4DXL A;  4JI3 E;  1S4E A;  3GCM A;  4PU9 A;  1ZXM A;  3Q6M A;  3LNU A;  3QT6 A;  3GME A;  1HNX E;  1XNQ E;  5DRO A;  4LFC E;  3J80 C;  4DR3 I;  1XNR E;  3Q6N A;  4ZVI A;  5DNX A;  1B62 A;  4JV5 I;  1DAR A;  5LMU E;  2GO4 A;  1E3H A;  1J5E I;  1ZM4 A;  4DUY E;  2UUA E;  1MX0 A;  2O3Z A;  3M6A A;  3K85 A;  4LFA I;  1Y6Z A;  2V2Z A;  4DU7 A;  1N36 I;  4X66 I;  4JI0 I;  4DR2 E;  2IER A;  5LMN I;  1EI1 A;  3T1H I;  3ZZU A;  2UUC I;  1XHK A;  2DEJ A;  5A2Q Q;  1FWL A;  4RPF A;  4DPU A;  1Z0G A;  1FI4 A;  5DRQ A;  2GO3 A;  1N0U A;  2C38 A;  2J7K A;  4BA1 A;  1RHY A;  2O1T A;  4IFD B;  3B82 A;  2R42 A;  2X7I A;  2V8P A;  4X65 I;  4DR3 E;  1XNR I;  4LFC I;  2UU9 I;  1UDO A;  2DEI A;  5IT9 C;  1N32 I;  1Z0C A;  4EMD A;  2XEX A;  4JI6 E;  4FWH A;  4AID A;  1S16 A;  1XMQ I;  1Z0T A;  1PVG A;  4X64 E;  2F4V E;  2E5L E;  3HUL A;  2PNZ B;  4JI4 I;  1UEK A;  4FWG A;  2E1R A;  3J80 Q;  4LCF A;  1KTV A;  1YH8 A;  3WU3 A;  2BM1 A;  4DR2 I;  1YHC A;  4DV5 I;  4JI1 I;  4JI8 I;  1HNZ E;  4DV7 I;  1NHJ A;  1Z0V A;  3PYF A;  5JEA A;  4HAC A;  2C39 A;  4DR5 I;  1HK7 A;  2A2C A;  4HY1 A;  2OI2 A;  2BV3 A;  4R1F A;  4JV5 E;  2J65 A;  3JAM C;  4AQY I;  2Z5B A;  4B3S E;  2PO0 A;  3B4T A;  4OO1 B;  1IBL I;  4NXM E;  4LFB I;  1VI7 A;  4LF9 E;  2PO2 B;  1XMO I;  2V2Q A;  1H7U A;  4OO1 C;  2BR2 B;  3PYD A;  2O1V A;  4JI5 I;  3CWV A;  1ZM3 A;  3J81 C;  4AIM A;  3ZKB A;  1HNX I;  2HFS A;  1H74 A;  4OX9 E;  4DUZ E;  1HNW E;  5C0X D;  2C37 A;  2NN6 A;  5GME A;  4MU1 A;  4OKG A;  1NHI A;  1Y4U A;  2VQE E;  3ZM7 A;  1FNM A;  2WNR A;  4JI2 E;  1Z0B A;  1R6M A;  4JI7 E;  2VQF I;  2UXB E;  4IFD A;  4DV1 I;  4NBQ A;  3U1K A;  3Q1Q A;  4B3T E;  4B3M I;  1OYP A;  3V5R A;  5K36 C;  4K0K E;  4DV0 E;  4JI0 E;  1Y60 A;  3OTO E;  4YHH E;  2UXD I;  1KKH A;  2E5L I;  4DV6 E;  1N34 E;  5K36 F;  4LF5 E;  3M7N D;  3JAM Q;  4IFD F;  5FLX C;  4XTJ A;  3UHM A;  2BA0 D;  5C0X E;  3D4J A;  1PKP A;  5C0X A;  4LF9 I;  5LMU I;  3K1J A;  2CZ9 A;  4AQY E;  4B3S I;  4MQY A;  4GKK I;  1OJ4 A;  4DPT A;  2V2V A;  4Z7C A;  4X65 E;  3WU4 A;  4PRX A;  1N0V C;  3KRN A;  4KHP I;  4IFD D;  3T1Y E;  4KQV A;  4X66 E;  3ZKD A;  1ZXN A;  1Y5Y A;  2C38 B;  4BA1 B;  2UUB E;  4DR6 E;  4GQU A;  2JEA A;  1BKN A;  2V34 A;  4GKK E;  5EL9 A;  4NXN I;  2NN6 F;  4LCH A;  3CDI A;  4JG4 A;  4JI8 E;  2VQE I;  2NN6 D;  1UDN A;  4FW3 A;  4B3M E;  4K0K I;  1KVK A;  2HKE A;  1K47 A;  2ZIT A;  4BA2 A;  4LF5 I;  4FW5 A;  1HNZ I;  4LF8 E;  4OO1 F;  3J7A G;  1KIJ A;  4FWD A;  1P42 A;  4IZJ B;  4DV0 I;  1Z0E A;  2A2D A;  1H7S A;  4IS9 A;  2JT2 A;  3L7Z B;  3B8H A;  4FW4 A;  1VIS A;  1B63 A;  1PIE A;  5EKW A;  2AE8 A;  2BA0 G;  4FW9 A;  1N32 E;  4AM3 A;  1IBL E;  2F4V I;  2VES A;  4X62 E;  3V2U C;  3HKM A;  2Z5C A;  3WU6 A;  4B3R I;  2GS8 A;  1ZM2 A;  4MDT A;  3PS1 A;  3PYE A;  4ED4 A; 
#chains in the Genus database with same CATH homology
 4MU1 A;  2F1D A;  4MU4 A;  4QNK A;  4LOM A;  4GQU A;  5EL9 A;  2AE8 A;  5EKW A;  5DNL A;  4MU0 A;  1RHY A;  4QNJ A;  4MU3 A;  5ELW A;  5DNX A;  4LPF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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