4MU3A

The form a structure of an e21q catalytic mutant of a. thaliana igpd2 in complex with mn2+ and a mixture of its substrate, 2r3s-igp, and an inhibitor, 2s3s-igp, to 1.12 a resolution
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
186
structure length
186
Chain Sequence
SARIGEVKRETKQTNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase/lyase inhibitor
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
total genus 58
structure length 186
sequence length 186
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu3A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu3A02
4GQUA 4LOMA 1RHYA 2F1DA 4QNKA 4QNJA 4LPFA 5ELWA 5EKWA 4MU1A 4MU0A 5DNXA 4MU3A 5EL9A 4MU4A 2AE8A 5DNLA
chains in the Genus database with same CATH superfamily
4JI2I 3P06A 4DR6E 5C0XC 3ZKDA 3Q1QA 2HK2A 4NXMI 4MQYA 2GS8A 3ZZUA 4DV6I 1Z0VA 1MU5A 2UUAE 5JEAE 3D4JA 4J3DA 1PIEA 4X64E 4X62E 4X65I 2PNLA 1N36E 3U1KA 4MU3A 4JI0I 1XNRI 3UHMA 1YH8A 4MU0A 3WU3A 5JEAA 1N0UA 4FW9A 5C0XF 1USVA 4DR5E 5GMDA 1UDOA 4P52A 4UTGA 2NPFA 4ED4A 4FWGA 3K85A 2JEBA 2PO1A 4B3ME 4IFDF 2Z5BB 4DR7E 3H1CA 4DV3I 2A2CA 2BR2B 3H4LA 5LMNI 5LMUE 4NBQA 5GMEA 2ZITA 5K36B 1HR0E 2NN6D 1NHHA 1KIJA 4KHPE 1XNRE 1UDSA 4NXNE 1Y4SA 2PNZB 3WU6A 1ZM4A 4B3SE 3DD6A 3J7AM 2DEIA 4USMA 4YHHI 2Z5CA 4IFDA 4OO1E 1Z0EA 1I94E 4IFDE 4U3DA 2PNMA 2XEXA 1IBME 1XMOE 1N33E 3V5RA 3OTOE 4DV2E 2IERA 4DR3E 4JI6I 4DV1E 5JEAC 4OX9E 5K36D 4DV0E 1FI4A 2NN6B 4GKJE 2BM1A 4BA2A 2IESA 2O3ZA 3JAMC 5JEAD 4DV0I 5FLXC 2HKJA 5K36C 1RR9A 1Z0TA 3PYEA 4M1KA 3QT7A 5A2QC 2NN6A 1B63A 4JI7I 2VF3A 3LTOA 4DU8A 4ISAA 1J5EI 2F1DA 4JI1E 1Z5AA 1I94I 3Q6MA 2UXDE 4AIMA 3B82A 2JE6A 3K1JA 2PO2A 4DV2I 4DUZI 1UDNA 2C37B 4MYTA 1N36I 2UUCE 1FJGI 1K47A 5JEAB 1Z5BA 1FWKA 4JI7E 2WP8A 1U2RA 4DV4E 2J7KA 2JE6B 3CDIA 4DV5I 3P3EA 1IBKE 4FN5A 1MX0A 4NXNI 4KHPI 3J7AG 5A2QQ 5FWKA 4QNKA 2NN6E 5LMNE 1FJGE 2UUCI 3GMEA 2HFUA 4AM3A 3PYGA 2CZ9A 5LL6R 4YY3I 4X66E 2ZM6E 4Z7CA 4B3RI 4DR2I 2BA1D 1RHYA 3CDJA 4LF6I 2Z5CB 1MG7A 4IFDB 4HYMA 5BR8E 1NHIA 3F0NA 4P7AA 4JI0E 1HK7A 2ZBKB 4FW4A 4WUDA 4LF4I 4X66I 2NN6C 2ZM6I 4LFBI 4URLA 4DUYE 2BA1G 2PO0A 1NZ0A 4MDTA 4OO1A 5C0XA 4DV1I 4DR3I 2UUAI 4JI6E 4OX9I 2O1VA 4NXME 4LF9E 4GKKI 5DRRA 1FWLA 5DRPA 4JYAI 4FWDA 3ZZ0A 4B3MI 2PNZA 4LF8I 2GO4A 3L7ZA 1H72C 2C38B 1HNXE 4OO1F 1HNWE 4DR2E 3HJCA 4JI8I 3PRYA 3B4TA 2WW4A 3T1YE 2JT2A 2VQFE 4B3TE 2E1RA 4DXLA 3P3GA 1Z59A 2OI2A 2GO3A 4JG4A 1H74A 4DPWA 5LMUI 4EMDA 2IOQA 4FW3A 4LCHA 4DR7I 1S4EA 2CG9A 2GQ0A 4JI8E 1ZM2A 2E5LI 1Y4UA 1Z5CA 1Z0GA 4DV4I 1J5EE 1EI1A 1QZRA 4JV5I 4PU9A 2JEAA 2BM0A 4OO1C 3P76A 4LF8E 1XNQI 4DU7A 1PVGA 4DPYA 5L3JA 3T1HI 3GONA 5JEAF 2CGEA 4X65E 5ELWA 4IFDD 2VQFI 2X7IA 4LF4E 1OYSA 4FW7A 4X64I 1H7SA 2UXCE 5DNLA 1OYRA 4BA2B 4LF5I 4LPFA 5C0XE 2F4VI 3J81C 4LFCI 3U1YA 2V8PA 4LF7I 2UUBE 4QNJA 4B3SI 2AJ4A 1WUUA 4GQUA 1DARA 5IT9Q 3M85G 4JI5E 1ZXMA 4DUYI 1FNMA 4LFAI 1XMQI 1OYPA 2IOPA 1XMOI 3L7ZB 5IT9C 2C38A 4FWHA 2UXCI 3M85D 4IZKB 5EL9A 2HKEA 5K36A 4HXZA 1N32E 1Y6ZA 4BA1A 2UXBI 2J65A 2JEBB 4DR1I 2HHHI 4LF9I 4GKKE 3LNUA 3P3CA 2Q2EB 4JI1I 3JAMQ 3M7NG 4LOMA 4JI5I 3QT8A 4HACA 1HNWI 4DV7E 4IFDC 1E3HA 3HKMA 3LPSA 4OKGA 4N3OA 4JYAE 1S16A 1XXEA 3Q6NA 2JEAB 1N34I 2C39B 4LFAE 2BA0D 4LF6E 2BV3A 3B78A 1Y60A 4WUBA 2V2ZA 1ZXNA 1KKHA 3KRNA 1BKNA 4AIDA 5K36E 1H73A 3GCMA 2UUBI 4DR1E 2HHHE 4HY1A 4AQYI 2O1TA 5DRQA 2PO0B 5C0XB 3OTOI 1EA6A 3PS3A 1VI7A 2WP8B 2HK3A 5EKWA 4JI2E 4FW5A 4YHHE 1Z0BA 4OO1D 4YY3E 2X36A 4PRVA 2C37A 1P42A 3ZM7A 4DV7I 4GKJI 1XMQE 2VQEE 4LCFA 1ZM9A 5IWAE 3PS1A 4MU1A 2O1UA 4IZJB 1IBKI 4JI4I 4K0KE 1B62A 3WU4A 4WUCA 4MU4A 4PRXA 4IS9A 1XHKA 5C0XD 4JV5E 1A6FA 1D6TA 2R3VA 1N0VC 4IZJA 2E5LE 2LJPA 3NZKA 1HNZE 3J81Q 2V34A 1UDQA 4OO1B 2UU9I 1Y5YA 2NN6F 2WNRA 2UXBE 1KVKA 1HR0I 4JI4E 4JI3E 4DR4I 1N32I 3WU5A 4IZJD 4X62I 3T1HE 4BA1B 2VQEI 1UEKA 1HNXI 3QT6A 2PO2B 1XNQE 1E3PA 2Z5BA 1N34E 4R1FA 2EFGA 2F4VE 4DR6I 1IBMI 4ZVIA 4AQYE 3PS2A 2V2VA 5DROA 2BA0G 2R42A 2A2DA 4B3RE 1R6MA 4LCGA 4JI3I 4DR4E 1Z0WA 1ZM3A 1IBLI 2HFSA 2UXDI 3K17A 5K36F 5BR8I 4B3TI 3J80Q 2UU9E 2AE8A 2CVEA 3M7ND 1NHJA 4U3BA 2VESA 1RREA 3GLLA 1Z0CA 4DPXA 1R6LA 4DR5I 2BR2A 4KQVA 4RPFA 1VISA 3ZKBA 4I3HA 1ELOA 2PO1B 4K0KI 4IZKA 4Z7YA 4DV3E 5FLXQ 5DNXA 4FW6A 2O1WA 5IWAI 4DV5E 1FKAE 4UT4A 4LFBE 4MYUA 1USUA 1N33I 3PYDA 1HNZI 4LF7E 3T1YI 3B8HA 4LFCE 1YHCA 3QT5A 1PKPA 3ZZTA 3PYFA 1H7UA 4LF5E 2Z5EA 1IBLE 4USKA 4DUZE 4HACB 4DPTA 4DPUA 4OZEA 1KTVA 3M6AA 2C39A 3HULA 2WNRB 2V2QA 4XTJA 3CWVA 4DV6E 3V2UC 3J80C 1OJ4A 2DEJA
chains in the Genus database with same CATH topology
4GQUA 4LOMA 1RHYA 2F1DA 4QNKA 4QNJA 4LPFA 5ELWA 5EKWA 4MU1A 4MU0A 5DNXA 4MU3A 5EL9A 4MU4A 2AE8A 5DNLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GQU A;  4LOM A;  1RHY A;  2F1D A;  4QNK A;  4QNJ A;  4LPF A;  5ELW A;  5EKW A;  4MU1 A;  4MU0 A;  5DNX A;  4MU3 A;  5EL9 A;  4MU4 A;  2AE8 A;  5DNL A; 
#chains in the Genus database with same CATH topology
 4JI2 I;  3P06 A;  4DR6 E;  5C0X C;  3ZKD A;  3Q1Q A;  2HK2 A;  4NXM I;  4MQY A;  2GS8 A;  3ZZU A;  4DV6 I;  1Z0V A;  1MU5 A;  2UUA E;  5JEA E;  3D4J A;  4J3D A;  1PIE A;  4X64 E;  4X62 E;  4X65 I;  2PNL A;  1N36 E;  3U1K A;  4MU3 A;  4JI0 I;  1XNR I;  3UHM A;  1YH8 A;  4MU0 A;  3WU3 A;  5JEA A;  1N0U A;  4FW9 A;  5C0X F;  1USV A;  4DR5 E;  5GMD A;  1UDO A;  4P52 A;  4UTG A;  2NPF A;  4ED4 A;  4FWG A;  3K85 A;  2JEB A;  2PO1 A;  4B3M E;  4IFD F;  2Z5B B;  4DR7 E;  3H1C A;  4DV3 I;  2A2C A;  2BR2 B;  3H4L A;  5LMN I;  5LMU E;  4NBQ A;  5GME A;  2ZIT A;  5K36 B;  1HR0 E;  2NN6 D;  1NHH A;  1KIJ A;  4KHP E;  1XNR E;  1UDS A;  4NXN E;  1Y4S A;  2PNZ B;  3WU6 A;  1ZM4 A;  4B3S E;  3DD6 A;  3J7A M;  2DEI A;  4USM A;  4YHH I;  2Z5C A;  4IFD A;  4OO1 E;  1Z0E A;  1I94 E;  4IFD E;  4U3D A;  2PNM A;  2XEX A;  1IBM E;  1XMO E;  1N33 E;  3V5R A;  3OTO E;  4DV2 E;  2IER A;  4DR3 E;  4JI6 I;  4DV1 E;  5JEA C;  4OX9 E;  5K36 D;  4DV0 E;  1FI4 A;  2NN6 B;  4GKJ E;  2BM1 A;  4BA2 A;  2IES A;  2O3Z A;  3JAM C;  5JEA D;  4DV0 I;  5FLX C;  2HKJ A;  5K36 C;  1RR9 A;  1Z0T A;  3PYE A;  4M1K A;  3QT7 A;  5A2Q C;  2NN6 A;  1B63 A;  4JI7 I;  2VF3 A;  3LTO A;  4DU8 A;  4ISA A;  1J5E I;  2F1D A;  4JI1 E;  1Z5A A;  1I94 I;  3Q6M A;  2UXD E;  4AIM A;  3B82 A;  2JE6 A;  3K1J A;  2PO2 A;  4DV2 I;  4DUZ I;  1UDN A;  2C37 B;  4MYT A;  1N36 I;  2UUC E;  1FJG I;  1K47 A;  5JEA B;  1Z5B A;  1FWK A;  4JI7 E;  2WP8 A;  1U2R A;  4DV4 E;  2J7K A;  2JE6 B;  3CDI A;  4DV5 I;  3P3E A;  1IBK E;  4FN5 A;  1MX0 A;  4NXN I;  4KHP I;  3J7A G;  5A2Q Q;  5FWK A;  4QNK A;  2NN6 E;  5LMN E;  1FJG E;  2UUC I;  3GME A;  2HFU A;  4AM3 A;  3PYG A;  2CZ9 A;  5LL6 R;  4YY3 I;  4X66 E;  2ZM6 E;  4Z7C A;  4B3R I;  4DR2 I;  2BA1 D;  1RHY A;  3CDJ A;  4LF6 I;  2Z5C B;  1MG7 A;  4IFD B;  4HYM A;  5BR8 E;  1NHI A;  3F0N A;  4P7A A;  4JI0 E;  1HK7 A;  2ZBK B;  4FW4 A;  4WUD A;  4LF4 I;  4X66 I;  2NN6 C;  2ZM6 I;  4LFB I;  4URL A;  4DUY E;  2BA1 G;  2PO0 A;  1NZ0 A;  4MDT A;  4OO1 A;  5C0X A;  4DV1 I;  4DR3 I;  2UUA I;  4JI6 E;  4OX9 I;  2O1V A;  4NXM E;  4LF9 E;  4GKK I;  5DRR A;  1FWL A;  5DRP A;  4JYA I;  4FWD A;  3ZZ0 A;  4B3M I;  2PNZ A;  4LF8 I;  2GO4 A;  3L7Z A;  1H72 C;  2C38 B;  1HNX E;  4OO1 F;  1HNW E;  4DR2 E;  3HJC A;  4JI8 I;  3PRY A;  3B4T A;  2WW4 A;  3T1Y E;  2JT2 A;  2VQF E;  4B3T E;  2E1R A;  4DXL A;  3P3G A;  1Z59 A;  2OI2 A;  2GO3 A;  4JG4 A;  1H74 A;  4DPW A;  5LMU I;  4EMD A;  2IOQ A;  4FW3 A;  4LCH A;  4DR7 I;  1S4E A;  2CG9 A;  2GQ0 A;  4JI8 E;  1ZM2 A;  2E5L I;  1Y4U A;  1Z5C A;  1Z0G A;  4DV4 I;  1J5E E;  1EI1 A;  1QZR A;  4JV5 I;  4PU9 A;  2JEA A;  2BM0 A;  4OO1 C;  3P76 A;  4LF8 E;  1XNQ I;  4DU7 A;  1PVG A;  4DPY A;  5L3J A;  3T1H I;  3GON A;  5JEA F;  2CGE A;  4X65 E;  5ELW A;  4IFD D;  2VQF I;  2X7I A;  4LF4 E;  1OYS A;  4FW7 A;  4X64 I;  1H7S A;  2UXC E;  5DNL A;  1OYR A;  4BA2 B;  4LF5 I;  4LPF A;  5C0X E;  2F4V I;  3J81 C;  4LFC I;  3U1Y A;  2V8P A;  4LF7 I;  2UUB E;  4QNJ A;  4B3S I;  2AJ4 A;  1WUU A;  4GQU A;  1DAR A;  5IT9 Q;  3M85 G;  4JI5 E;  1ZXM A;  4DUY I;  1FNM A;  4LFA I;  1XMQ I;  1OYP A;  2IOP A;  1XMO I;  3L7Z B;  5IT9 C;  2C38 A;  4FWH A;  2UXC I;  3M85 D;  4IZK B;  5EL9 A;  2HKE A;  5K36 A;  4HXZ A;  1N32 E;  1Y6Z A;  4BA1 A;  2UXB I;  2J65 A;  2JEB B;  4DR1 I;  2HHH I;  4LF9 I;  4GKK E;  3LNU A;  3P3C A;  2Q2E B;  4JI1 I;  3JAM Q;  3M7N G;  4LOM A;  4JI5 I;  3QT8 A;  4HAC A;  1HNW I;  4DV7 E;  4IFD C;  1E3H A;  3HKM A;  3LPS A;  4OKG A;  4N3O A;  4JYA E;  1S16 A;  1XXE A;  3Q6N A;  2JEA B;  1N34 I;  2C39 B;  4LFA E;  2BA0 D;  4LF6 E;  2BV3 A;  3B78 A;  1Y60 A;  4WUB A;  2V2Z A;  1ZXN A;  1KKH A;  3KRN A;  1BKN A;  4AID A;  5K36 E;  1H73 A;  3GCM A;  2UUB I;  4DR1 E;  2HHH E;  4HY1 A;  4AQY I;  2O1T A;  5DRQ A;  2PO0 B;  5C0X B;  3OTO I;  1EA6 A;  3PS3 A;  1VI7 A;  2WP8 B;  2HK3 A;  5EKW A;  4JI2 E;  4FW5 A;  4YHH E;  1Z0B A;  4OO1 D;  4YY3 E;  2X36 A;  4PRV A;  2C37 A;  1P42 A;  3ZM7 A;  4DV7 I;  4GKJ I;  1XMQ E;  2VQE E;  4LCF A;  1ZM9 A;  5IWA E;  3PS1 A;  4MU1 A;  2O1U A;  4IZJ B;  1IBK I;  4JI4 I;  4K0K E;  1B62 A;  3WU4 A;  4WUC A;  4MU4 A;  4PRX A;  4IS9 A;  1XHK A;  5C0X D;  4JV5 E;  1A6F A;  1D6T A;  2R3V A;  1N0V C;  4IZJ A;  2E5L E;  2LJP A;  3NZK A;  1HNZ E;  3J81 Q;  2V34 A;  1UDQ A;  4OO1 B;  2UU9 I;  1Y5Y A;  2NN6 F;  2WNR A;  2UXB E;  1KVK A;  1HR0 I;  4JI4 E;  4JI3 E;  4DR4 I;  1N32 I;  3WU5 A;  4IZJ D;  4X62 I;  3T1H E;  4BA1 B;  2VQE I;  1UEK A;  1HNX I;  3QT6 A;  2PO2 B;  1XNQ E;  1E3P A;  2Z5B A;  1N34 E;  4R1F A;  2EFG A;  2F4V E;  4DR6 I;  1IBM I;  4ZVI A;  4AQY E;  3PS2 A;  2V2V A;  5DRO A;  2BA0 G;  2R42 A;  2A2D A;  4B3R E;  1R6M A;  4LCG A;  4JI3 I;  4DR4 E;  1Z0W A;  1ZM3 A;  1IBL I;  2HFS A;  2UXD I;  3K17 A;  5K36 F;  5BR8 I;  4B3T I;  3J80 Q;  2UU9 E;  2AE8 A;  2CVE A;  3M7N D;  1NHJ A;  4U3B A;  2VES A;  1RRE A;  3GLL A;  1Z0C A;  4DPX A;  1R6L A;  4DR5 I;  2BR2 A;  4KQV A;  4RPF A;  1VIS A;  3ZKB A;  4I3H A;  1ELO A;  2PO1 B;  4K0K I;  4IZK A;  4Z7Y A;  4DV3 E;  5FLX Q;  5DNX A;  4FW6 A;  2O1W A;  5IWA I;  4DV5 E;  1FKA E;  4UT4 A;  4LFB E;  4MYU A;  1USU A;  1N33 I;  3PYD A;  1HNZ I;  4LF7 E;  3T1Y I;  3B8H A;  4LFC E;  1YHC A;  3QT5 A;  1PKP A;  3ZZT A;  3PYF A;  1H7U A;  4LF5 E;  2Z5E A;  1IBL E;  4USK A;  4DUZ E;  4HAC B;  4DPT A;  4DPU A;  4OZE A;  1KTV A;  3M6A A;  2C39 A;  3HUL A;  2WNR B;  2V2Q A;  4XTJ A;  3CWV A;  4DV6 E;  3V2U C;  3J80 C;  1OJ4 A;  2DEJ A; 
#chains in the Genus database with same CATH homology
 4GQU A;  4LOM A;  1RHY A;  2F1D A;  4QNK A;  4QNJ A;  4LPF A;  5ELW A;  5EKW A;  4MU1 A;  4MU0 A;  5DNX A;  4MU3 A;  5EL9 A;  4MU4 A;  2AE8 A;  5DNL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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