4MU3A

The form a structure of an e21q catalytic mutant of a. thaliana igpd2 in complex with mn2+ and a mixture of its substrate, 2r3s-igp, and an inhibitor, 2s3s-igp, to 1.12 a resolution
Total Genus 58
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
186
structure length
186
Chain Sequence
SARIGEVKRETKQTNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRG
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
molecule tags Lyase/lyase inhibitor
total genus 58
structure length 186
sequence length 186
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu3A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu3A02
4QNKA 5DNLA 4LPFA 4GQUA 4MU4A 5EKWA 4MU1A 2F1DA 4QNJA 5ELWA 1RHYA 4MU3A 5DNXA 5EL9A 2AE8A 4LOMA 4MU0A
chains in the Genus database with same CATH superfamily
2Z5EA 1HNWE 4X65I 5IT9Q 2UXCE 1E3PA 4JI3E 4GKKE 3P3CA 2HK3A 5IWAE 4JI7I 4PRVA 5DRRA 1I94E 3LPSA 1FKAE 3J81C 2PNZB 3JAMQ 4OO1F 4IFDE 4KHPE 4IFDC 5K36B 2BV3A 1S16A 1XMOI 3K85A 3ZZTA 3V5RA 4FWHA 4LF5E 1D6TA 2J65A 4DR5I 3PYDA 1PIEA 1RREA 3V2UC 4LFAI 3NZKA 5EKWA 1HNZE 4URLA 4DU7A 2O1WA 4LFBE 4ED4A 4DPWA 2DEJA 5LMNI 4LPFA 4B3TI 4N3OA 3ZM7A 1XNQI 1Z5AA 2HHHI 1FJGE 4MU0A 4QNKA 3B78A 2BM1A 4P7AA 4LF6E 2UUCE 4JI2E 4B3MI 4NXME 4DR4E 2UXDI 4JV5E 1N34I 5ELWA 4DV6E 4MU3A 1N0VC 4IZJB 4LF4E 2Z5BB 4LCFA 1N32I 4DV1I 4K0KE 1VI7A 5LL6R 4LCHA 4DV7E 3T1YI 2XEXA 1XMQE 4ISAA 2VQFE 4BA2A 4R1FA 5JEAA 4IZJD 4LFCE 1B63A 1J5EE 5K36F 1UDOA 4USMA 4DUYI 4JI6I 4HY1A 2NN6A 4MU1A 1BKNA 2IESA 3WU6A 4X65E 1KIJA 4LF7I 2GQ0A 4OO1B 4DR7I 1KKHA 1USVA 4JI7E 4YHHI 1UDNA 1H7SA 3J81Q 2A2CA 3PS3A 4DR3I 3B8HA 4FW6A 2IOPA 2EFGA 4FW7A 4YY3E 4OO1D 3M85D 3Q6MA 4DV4I 1MG7A 2ZM6I 1XMOE 5DRPA 3H1CA 2JEBA 1MX0A 2GO3A 5L3JA 4BA1A 4DR5E 1IBMI 5JEAE 2BA1D 4X62I 2PO1B 5JEAC 4HACA 2PO0B 1WUUA 2UUBE 4EMDA 2NN6E 1RHYA 2C37A 4DPUA 2WNRB 2X7IA 2NN6C 5C0XA 3HKMA 2C38A 2GS8A 5LMNE 2IERA 4AQYI 1UDQA 4M1KA 3CDJA 2PNMA 4HYMA 1H72C 3L7ZA 4DXLA 1USUA 1XXEA 1FWLA 3T1HI 1A6FA 5BR8I 5GMDA 2F4VI 4B3ME 4UTGA 3GONA 1OYSA 2UXDE 1RR9A 1N34E 1Y5YA 4DPYA 1NHJA 3M6AA 1Z0GA 4DR6I 3WU3A 1KVKA 4ZVIA 1IBKI 2WP8A 1N36I 4UT4A 4JI0I 1N32E 5EL9A 2CZ9A 2UXBI 3GMEA 3H4LA 2WW4A 2F1DA 1B62A 2V2ZA 1Z0CA 3UHMA 4XTJA 1U2RA 4RPFA 4DR2I 1H7UA 4DUYE 4B3SI 5K36D 4JI6E 5LMUE 5C0XE 1XNRI 4DUZI 4DV2I 3F0NA 3J80C 2UU9I 3GLLA 5C0XC 4LF8I 4LF7E 4DR7E 1FWKA 3P3GA 2PNZA 2BR2B 1H73A 4YHHE 3OTOI 1FI4A 5A2QC 3P3EA 4LOMA 3K17A 4X64I 4DR3E 1IBLE 4QNJA 3M7NG 2JE6A 4GQUA 4IZKA 4JYAI 4JI8I 2VESA 4JI1I 2VQEI 4AM3A 3QT6A 4HXZA 4NXNI 4KQVA 1Z5BA 4BA2B 2ZITA 2Z5CB 1Y4SA 4DV0I 1HNXI 1ZM4A 4X62E 4FW3A 4OZEA 4JI3I 1Z0TA 1NHIA 2JEAA 3ZZ0A 1P42A 1YH8A 4X66I 2O1VA 3J7AG 3P06A 4GKJE 4AQYE 1Z5CA 1PKPA 3JAMC 2JT2A 4NBQA 2E5LI 4MU4A 2AJ4A 3T1HE 4JI4I 5BR8E 3Q1QA 1ZM3A 2BA0G 1Y4UA 4IZJA 3ZKBA 2HKEA 1FNMA 3M7ND 2Z5BA 1XHKA 4IFDB 4MDTA 1IBKE 4MYUA 5DNLA 1N36E 1OJ4A 4JI0E 4U3DA 5DNXA 4B3RI 2GO4A 4FW5A 2V2VA 4HACB 4LF9I 3LTOA 3GCMA 4MYTA 4DR2E 4IFDD 2LJPA 4Z7CA 2CGEA 4B3SE 3KRNA 2C37B 2PO2A 4OO1A 4AIMA 5C0XB 1FJGI 2AE8A 4LFAE 1XNRE 4DUZE 3J80Q 2DEIA 2UU9E 1Z59A 1Z0WA 5JEAF 4B3TE 1NHHA 3OTOE 3WU5A 5A2QQ 4DV6I 1XNQE 2X36A 2HHHE 4DV5I 1ELOA 4USKA 3K1JA 4LF4I 1E3HA 2HKJA 3PS2A 2NN6F 2CG9A 3QT8A 1EA6A 2V2QA 2WP8B 4OX9I 1R6LA 3PS1A 4JYAE 4K0KI 2R42A 4JI8E 2HFUA 4JI1E 3PYGA 2C39A 2PO1A 2PO0A 4DR1I 2HFSA 1Z0BA 4DV1E 1QZRA 4FW4A 4DV0E 1HNXE 3U1YA 3T1YE 4DV3I 2WNRA 3HJCA 3HULA 4FN5A 2O1TA 3Q6NA 4PRXA 1DARA 4DU8A 1N33I 4IFDF 4OO1E 1OYPA 4OO1C 4X66E 5DRQA 4J3DA 3WU4A 3ZZUA 1OYRA 2O1UA 5FLXC 1MU5A 4JG4A 3B82A 4LCGA 1UDSA 4YY3I 2E5LE 4JI4E 3B4TA 1R6MA 4P52A 2JE6B 1HR0I 1H74A 5C0XF 1Z0VA 5K36A 4IZKB 4OKGA 2OI2A 3PYFA 3QT5A 2A2DA 3QT7A 2UUAI 4JI5I 5GMEA 1PVGA 3P76A 2O3ZA 2J7KA 1Y60A 2R3VA 4DV4E 2ZM6E 4B3RE 2UUBI 2CVEA 3LNUA 4LF9E 1UEKA 2JEAB 3D4JA 5JEAB 4WUBA 2V8PA 1IBME 4FWGA 1HNWI 5IT9C 2VF3A 3U1KA 2UXCI 1VISA 2BR2A 2IOQA 4GKKI 2NN6B 1HK7A 1EI1A 5IWAI 4MQYA 4FWDA 4I3HA 3J7AM 3DD6A 1I94I 2ZBKB 3CDIA 5JEAD 3M85G 4DV5E 1ZM9A 4KHPI 1NZ0A 5K36E 2BM0A 2NN6D 5K36C 1YHCA 4OX9E 2F4VE 4LF5I 2Z5CA 2BA1G 2Q2EB 4AIDA 2E1RA 4DPXA 4DR6E 1K47A 2PNLA 1KTVA 4DR1E 5LMUI 2JEBB 1Z0EA 1S4EA 4BA1B 5FWKA 2UXBE 4DV3E 1HNZI 1ZXNA 4LFBI 2PO2B 4DPTA 1N33E 5DROA 4WUDA 1ZXMA 5FLXQ 2C38B 3ZKDA 1IBLI 4DV2E 2V34A 4LF6I 4LF8E 2UUCI 4IS9A 4U3BA 4Z7YA 4JI2I 4DR4I 1ZM2A 3L7ZB 4NXMI 1HR0E 4IFDA 4JV5I 3CWVA 4X64E 4FW9A 5C0XD 2BA0D 3PYEA 2UUAE 2C39B 4PU9A 4JI5E 1N0UA 2NPFA 4DV7I 1Y6ZA 4WUCA 1XMQI 2VQFI 2HK2A 2VQEE 4NXNE 3PRYA 4LFCI 1J5EI 4GKJI
chains in the Genus database with same CATH topology
4QNKA 5DNLA 4LPFA 4GQUA 4MU4A 5EKWA 4MU1A 2F1DA 4QNJA 5ELWA 1RHYA 4MU3A 5DNXA 5EL9A 2AE8A 4LOMA 4MU0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QNK A;  5DNL A;  4LPF A;  4GQU A;  4MU4 A;  5EKW A;  4MU1 A;  2F1D A;  4QNJ A;  5ELW A;  1RHY A;  4MU3 A;  5DNX A;  5EL9 A;  2AE8 A;  4LOM A;  4MU0 A; 
#chains in the Genus database with same CATH topology
 2Z5E A;  1HNW E;  4X65 I;  5IT9 Q;  2UXC E;  1E3P A;  4JI3 E;  4GKK E;  3P3C A;  2HK3 A;  5IWA E;  4JI7 I;  4PRV A;  5DRR A;  1I94 E;  3LPS A;  1FKA E;  3J81 C;  2PNZ B;  3JAM Q;  4OO1 F;  4IFD E;  4KHP E;  4IFD C;  5K36 B;  2BV3 A;  1S16 A;  1XMO I;  3K85 A;  3ZZT A;  3V5R A;  4FWH A;  4LF5 E;  1D6T A;  2J65 A;  4DR5 I;  3PYD A;  1PIE A;  1RRE A;  3V2U C;  4LFA I;  3NZK A;  5EKW A;  1HNZ E;  4URL A;  4DU7 A;  2O1W A;  4LFB E;  4ED4 A;  4DPW A;  2DEJ A;  5LMN I;  4LPF A;  4B3T I;  4N3O A;  3ZM7 A;  1XNQ I;  1Z5A A;  2HHH I;  1FJG E;  4MU0 A;  4QNK A;  3B78 A;  2BM1 A;  4P7A A;  4LF6 E;  2UUC E;  4JI2 E;  4B3M I;  4NXM E;  4DR4 E;  2UXD I;  4JV5 E;  1N34 I;  5ELW A;  4DV6 E;  4MU3 A;  1N0V C;  4IZJ B;  4LF4 E;  2Z5B B;  4LCF A;  1N32 I;  4DV1 I;  4K0K E;  1VI7 A;  5LL6 R;  4LCH A;  4DV7 E;  3T1Y I;  2XEX A;  1XMQ E;  4ISA A;  2VQF E;  4BA2 A;  4R1F A;  5JEA A;  4IZJ D;  4LFC E;  1B63 A;  1J5E E;  5K36 F;  1UDO A;  4USM A;  4DUY I;  4JI6 I;  4HY1 A;  2NN6 A;  4MU1 A;  1BKN A;  2IES A;  3WU6 A;  4X65 E;  1KIJ A;  4LF7 I;  2GQ0 A;  4OO1 B;  4DR7 I;  1KKH A;  1USV A;  4JI7 E;  4YHH I;  1UDN A;  1H7S A;  3J81 Q;  2A2C A;  3PS3 A;  4DR3 I;  3B8H A;  4FW6 A;  2IOP A;  2EFG A;  4FW7 A;  4YY3 E;  4OO1 D;  3M85 D;  3Q6M A;  4DV4 I;  1MG7 A;  2ZM6 I;  1XMO E;  5DRP A;  3H1C A;  2JEB A;  1MX0 A;  2GO3 A;  5L3J A;  4BA1 A;  4DR5 E;  1IBM I;  5JEA E;  2BA1 D;  4X62 I;  2PO1 B;  5JEA C;  4HAC A;  2PO0 B;  1WUU A;  2UUB E;  4EMD A;  2NN6 E;  1RHY A;  2C37 A;  4DPU A;  2WNR B;  2X7I A;  2NN6 C;  5C0X A;  3HKM A;  2C38 A;  2GS8 A;  5LMN E;  2IER A;  4AQY I;  1UDQ A;  4M1K A;  3CDJ A;  2PNM A;  4HYM A;  1H72 C;  3L7Z A;  4DXL A;  1USU A;  1XXE A;  1FWL A;  3T1H I;  1A6F A;  5BR8 I;  5GMD A;  2F4V I;  4B3M E;  4UTG A;  3GON A;  1OYS A;  2UXD E;  1RR9 A;  1N34 E;  1Y5Y A;  4DPY A;  1NHJ A;  3M6A A;  1Z0G A;  4DR6 I;  3WU3 A;  1KVK A;  4ZVI A;  1IBK I;  2WP8 A;  1N36 I;  4UT4 A;  4JI0 I;  1N32 E;  5EL9 A;  2CZ9 A;  2UXB I;  3GME A;  3H4L A;  2WW4 A;  2F1D A;  1B62 A;  2V2Z A;  1Z0C A;  3UHM A;  4XTJ A;  1U2R A;  4RPF A;  4DR2 I;  1H7U A;  4DUY E;  4B3S I;  5K36 D;  4JI6 E;  5LMU E;  5C0X E;  1XNR I;  4DUZ I;  4DV2 I;  3F0N A;  3J80 C;  2UU9 I;  3GLL A;  5C0X C;  4LF8 I;  4LF7 E;  4DR7 E;  1FWK A;  3P3G A;  2PNZ A;  2BR2 B;  1H73 A;  4YHH E;  3OTO I;  1FI4 A;  5A2Q C;  3P3E A;  4LOM A;  3K17 A;  4X64 I;  4DR3 E;  1IBL E;  4QNJ A;  3M7N G;  2JE6 A;  4GQU A;  4IZK A;  4JYA I;  4JI8 I;  2VES A;  4JI1 I;  2VQE I;  4AM3 A;  3QT6 A;  4HXZ A;  4NXN I;  4KQV A;  1Z5B A;  4BA2 B;  2ZIT A;  2Z5C B;  1Y4S A;  4DV0 I;  1HNX I;  1ZM4 A;  4X62 E;  4FW3 A;  4OZE A;  4JI3 I;  1Z0T A;  1NHI A;  2JEA A;  3ZZ0 A;  1P42 A;  1YH8 A;  4X66 I;  2O1V A;  3J7A G;  3P06 A;  4GKJ E;  4AQY E;  1Z5C A;  1PKP A;  3JAM C;  2JT2 A;  4NBQ A;  2E5L I;  4MU4 A;  2AJ4 A;  3T1H E;  4JI4 I;  5BR8 E;  3Q1Q A;  1ZM3 A;  2BA0 G;  1Y4U A;  4IZJ A;  3ZKB A;  2HKE A;  1FNM A;  3M7N D;  2Z5B A;  1XHK A;  4IFD B;  4MDT A;  1IBK E;  4MYU A;  5DNL A;  1N36 E;  1OJ4 A;  4JI0 E;  4U3D A;  5DNX A;  4B3R I;  2GO4 A;  4FW5 A;  2V2V A;  4HAC B;  4LF9 I;  3LTO A;  3GCM A;  4MYT A;  4DR2 E;  4IFD D;  2LJP A;  4Z7C A;  2CGE A;  4B3S E;  3KRN A;  2C37 B;  2PO2 A;  4OO1 A;  4AIM A;  5C0X B;  1FJG I;  2AE8 A;  4LFA E;  1XNR E;  4DUZ E;  3J80 Q;  2DEI A;  2UU9 E;  1Z59 A;  1Z0W A;  5JEA F;  4B3T E;  1NHH A;  3OTO E;  3WU5 A;  5A2Q Q;  4DV6 I;  1XNQ E;  2X36 A;  2HHH E;  4DV5 I;  1ELO A;  4USK A;  3K1J A;  4LF4 I;  1E3H A;  2HKJ A;  3PS2 A;  2NN6 F;  2CG9 A;  3QT8 A;  1EA6 A;  2V2Q A;  2WP8 B;  4OX9 I;  1R6L A;  3PS1 A;  4JYA E;  4K0K I;  2R42 A;  4JI8 E;  2HFU A;  4JI1 E;  3PYG A;  2C39 A;  2PO1 A;  2PO0 A;  4DR1 I;  2HFS A;  1Z0B A;  4DV1 E;  1QZR A;  4FW4 A;  4DV0 E;  1HNX E;  3U1Y A;  3T1Y E;  4DV3 I;  2WNR A;  3HJC A;  3HUL A;  4FN5 A;  2O1T A;  3Q6N A;  4PRX A;  1DAR A;  4DU8 A;  1N33 I;  4IFD F;  4OO1 E;  1OYP A;  4OO1 C;  4X66 E;  5DRQ A;  4J3D A;  3WU4 A;  3ZZU A;  1OYR A;  2O1U A;  5FLX C;  1MU5 A;  4JG4 A;  3B82 A;  4LCG A;  1UDS A;  4YY3 I;  2E5L E;  4JI4 E;  3B4T A;  1R6M A;  4P52 A;  2JE6 B;  1HR0 I;  1H74 A;  5C0X F;  1Z0V A;  5K36 A;  4IZK B;  4OKG A;  2OI2 A;  3PYF A;  3QT5 A;  2A2D A;  3QT7 A;  2UUA I;  4JI5 I;  5GME A;  1PVG A;  3P76 A;  2O3Z A;  2J7K A;  1Y60 A;  2R3V A;  4DV4 E;  2ZM6 E;  4B3R E;  2UUB I;  2CVE A;  3LNU A;  4LF9 E;  1UEK A;  2JEA B;  3D4J A;  5JEA B;  4WUB A;  2V8P A;  1IBM E;  4FWG A;  1HNW I;  5IT9 C;  2VF3 A;  3U1K A;  2UXC I;  1VIS A;  2BR2 A;  2IOQ A;  4GKK I;  2NN6 B;  1HK7 A;  1EI1 A;  5IWA I;  4MQY A;  4FWD A;  4I3H A;  3J7A M;  3DD6 A;  1I94 I;  2ZBK B;  3CDI A;  5JEA D;  3M85 G;  4DV5 E;  1ZM9 A;  4KHP I;  1NZ0 A;  5K36 E;  2BM0 A;  2NN6 D;  5K36 C;  1YHC A;  4OX9 E;  2F4V E;  4LF5 I;  2Z5C A;  2BA1 G;  2Q2E B;  4AID A;  2E1R A;  4DPX A;  4DR6 E;  1K47 A;  2PNL A;  1KTV A;  4DR1 E;  5LMU I;  2JEB B;  1Z0E A;  1S4E A;  4BA1 B;  5FWK A;  2UXB E;  4DV3 E;  1HNZ I;  1ZXN A;  4LFB I;  2PO2 B;  4DPT A;  1N33 E;  5DRO A;  4WUD A;  1ZXM A;  5FLX Q;  2C38 B;  3ZKD A;  1IBL I;  4DV2 E;  2V34 A;  4LF6 I;  4LF8 E;  2UUC I;  4IS9 A;  4U3B A;  4Z7Y A;  4JI2 I;  4DR4 I;  1ZM2 A;  3L7Z B;  4NXM I;  1HR0 E;  4IFD A;  4JV5 I;  3CWV A;  4X64 E;  4FW9 A;  5C0X D;  2BA0 D;  3PYE A;  2UUA E;  2C39 B;  4PU9 A;  4JI5 E;  1N0U A;  2NPF A;  4DV7 I;  1Y6Z A;  4WUC A;  1XMQ I;  2VQF I;  2HK2 A;  2VQE E;  4NXN E;  3PRY A;  4LFC I;  1J5E I;  4GKJ I; 
#chains in the Genus database with same CATH homology
 4QNK A;  5DNL A;  4LPF A;  4GQU A;  4MU4 A;  5EKW A;  4MU1 A;  2F1D A;  4QNJ A;  5ELW A;  1RHY A;  4MU3 A;  5DNX A;  5EL9 A;  2AE8 A;  4LOM A;  4MU0 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...