4MU3A

The form a structure of an e21q catalytic mutant of a. thaliana igpd2 in complex with mn2+ and a mixture of its substrate, 2r3s-igp, and an inhibitor, 2s3s-igp, to 1.12 a resolution
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
186
structure length
186
Chain Sequence
SARIGEVKRETKQTNVSVKINLDGHGVSDSSTGIPFLDHMLDQLASHGLFDVHVRATGDTHIDDHHTNEDVALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGKNSHHIIEATFKAFARALRQATESDPRRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase/lyase inhibitor
molecule keywords Imidazoleglycerol-phosphate dehydratase 2, chloroplastic
publication title Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination.
pubmed doi rcsb
source organism Arabidopsis thaliana
total genus 58
structure length 186
sequence length 186
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2013-09-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu3A01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 4mu3A02
2F1DA 4QNKA 1RHYA 5EL9A 5ELWA 4GQUA 4MU1A 4LOMA 5DNLA 2AE8A 4MU0A 4MU3A 5EKWA 4MU4A 5DNXA 4QNJA 4LPFA
chains in the Genus database with same CATH superfamily
1RREA 2VESA 1N34E 4AIDA 3V2UC 4NXNI 4GKJI 1RHYA 5C0XB 2Z5BB 3CWVA 4JI6E 4N3OA 4USKA 5DNXA 4KHPI 1FKAE 2V34A 4GKKE 4NXNE 4FW4A 3QT7A 1OYPA 4FWGA 3B82A 5L3JA 4BA2B 4DR2I 4DR4E 1HNWE 1ELOA 3QT6A 3LPSA 5IT9C 4DPUA 2VF3A 2HK3A 4I3HA 4DV7I 4LF8E 4DR2E 4IS9A 4IFDA 2JEAB 1U2RA 4WUCA 1PIEA 2HHHI 3M85D 1OYSA 4JI8I 2GQ0A 3T1YI 1KVKA 4DPXA 4DV6E 4UTGA 4EMDA 1HNXE 4AIMA 2UXBI 2AE8A 4ED4A 3GMEA 1XMQI 4JI0E 3T1YE 3P3CA 4JI7E 4DUZE 4FW6A 4X65I 1H73A 2UXBE 4LF9I 2C39A 3M85G 1IBMI 4PRXA 3PS1A 2VQFE 2F1DA 1PVGA 3PYDA 1Z0GA 1UDOA 1N36I 3ZKBA 4JYAI 1NHJA 2V8PA 4FWDA 3Q6MA 2J65A 4OKGA 3CDIA 2UXDI 4LOMA 4X66I 3DD6A 3K1JA 1Z0EA 5C0XD 4LCGA 4B3RI 1ZM9A 1Y6ZA 3K85A 4X66E 4YY3I 5JEAC 1B63A 1ZXMA 4OO1F 1P42A 1QZRA 4B3RE 2HFUA 1N0UA 2UUCI 1VISA 2WNRA 4JG4A 2A2DA 2UU9E 4RPFA 3H1CA 1S16A 4HYMA 2WW4A 5JEAE 4DV2I 3Q6NA 4DV0E 4B3MI 4WUBA 4IFDC 2BA0D 3L7ZB 4WUDA 4DUYI 2UUBI 3WU3A 3ZZTA 1N33I 4B3ME 4X62I 4DXLA 4DUYE 4IFDD 2V2VA 1OJ4A 2PO1B 3KRNA 4LFAI 4NXMI 5C0XF 4IFDE 4AQYI 4JI2E 4JI3E 1KKHA 3LTOA 2NN6C 2F4VI 1HNZI 2BA0G 4QNJA 4USMA 3ZM7A 1HK7A 5A2QC 4LF5E 2Z5EA 5BR8I 1N34I 1FNMA 3B4TA 1HNZE 3U1KA 2NN6D 4JI6I 3J80C 2NN6E 4J3DA 5BR8E 4GKKI 2PO0B 1N32I 4DPTA 1IBLE 3GCMA 4URLA 2BM1A 1WUUA 1HNWI 4DR4I 1XXEA 5FLXQ 1VI7A 2CZ9A 2JEBA 5JEAA 4DR3E 3JAMQ 1UEKA 1N32E 4IFDF 2GO3A 4IZKA 4LF8I 1R6MA 2PNLA 3B8HA 1XMOE 1E3PA 1H72C 5JEAB 3ZZUA 3GONA 5DRQA 5LMUE 4DV6I 4IZKB 1HNXI 1Z0BA 4LFCI 2EFGA 2LJPA 4JI0I 1S4EA 2ZM6I 4LF7I 4QNKA 1EA6A 4JI7I 4DUZI 4DU7A 4IZJA 4LFCE 4IFDB 2CG9A 1Z0TA 2UUAI 2C37A 5DNLA 2ZM6E 4LF7E 1MX0A 2VQFI 2NN6A 1MG7A 1I94I 4YHHI 1FI4A 2WP8A 4DV4E 1RR9A 2UUAE 1MU5A 2J7KA 4HACA 2V2ZA 4ZVIA 2C37B 2JE6A 1USUA 4YHHE 1I94E 4FW7A 2NN6B 2C39B 3U1YA 3UHMA 3PYGA 3J7AG 5K36A 2C38A 1ZM2A 4DR6E 4JI5I 3P06A 3PS2A 3PRYA 4DU8A 1N0VC 4JI1E 4JI5E 2AJ4A 2E1RA 2ZITA 3J81Q 1J5EI 4FN5A 1K47A 4HXZA 5EL9A 2UU9I 1HR0I 1A6FA 4DR5I 1Y4UA 3P76A 3PYEA 3PS3A 4U3BA 1J5EE 4U3DA 4DV0I 1HR0E 1H7SA 4DR5E 3T1HI 5JEAD 1OYRA 1PKPA 4MU0A 2HKJA 3P3EA 2O1TA 2R3VA 2WNRB 3T1HE 3P3GA 5DROA 3QT8A 4FW9A 3D4JA 4JI4I 4JI2I 4K0KE 1Z59A 4JI3I 4OZEA 5DRPA 2PNMA 3WU5A 1KTVA 2CVEA 4DPWA 2Z5CA 4LF5I 2E5LE 4JI4E 2VQEE 2HK2A 2CGEA 4PRVA 4OO1A 3HKMA 4MDTA 5IT9Q 1ZM4A 4IZJD 4DV3E 1NZ0A 2O3ZA 2BM0A 4DPYA 1BKNA 2PO2A 3H4LA 4LFBE 2BV3A 4DR1I 4BA1A 1IBLI 2IESA 5JEAF 4DR7E 4Z7YA 5K36C 1UDSA 1Z5CA 3J81C 4DR3I 3NZKA 4DR1E 3OTOE 1NHIA 2PO2B 2NPFA 1XNRI 4BA1B 5K36D 1XMOI 4FW3A 5GMDA 4DV5I 1FJGE 5K36E 2XEXA 2V2QA 4B3TE 4MU4A 1XNRE 5LMUI 3HJCA 2UXCE 3ZZ0A 4DV5E 1Y5YA 2JEBB 1IBKI 2JT2A 4OX9E 4BA2A 4NBQA 3B78A 4LF4I 1ZM3A 4AM3A 1D6TA 4M1KA 3QT5A 1IBKE 1B62A 4GKJE 2NN6F 5LL6R 4JV5I 4B3SI 4LF4E 2JEAA 2O1VA 2O1WA 4ISAA 1H74A 4KHPE 4DV4I 3Q1QA 1ZXNA 4LCHA 4JV5E 2A2CA 4B3SE 3M6AA 5K36F 4IZJB 1UDQA 1FWLA 1Z0WA 1UDNA 2O1UA 4DR6I 3ZKDA 4DV7E 4OO1C 2BR2A 2HKEA 2WP8B 2HHHE 5GMEA 4JI1I 4JI8E 1XHKA 2DEJA 4HACB 2ZBKB 5IWAI 5FLXC 4OO1D 2JE6B 2IERA 4OO1E 2BR2B 2X7IA 3JAMC 3GLLA 3V5RA 4DV1I 1YHCA 1XMQE 1YH8A 4P7AA 5K36B 5IWAE 2C38B 2R42A 4X65E 4MYTA 1Z5AA 4R1FA 4LF6I 4LF9E 4LPFA 1NHHA 4DV1E 1Z0VA 2GO4A 4FWHA 5FWKA 1IBME 5C0XC 1Y60A 4LF6E 2DEIA 2BA1D 3PYFA 5A2QQ 5LMNI 2IOQA 2PNZA 1XNQI 3J80Q 1N36E 1Z5BA 4JYAE 4K0KI 5C0XE 4MYUA 5LMNE 2UXDE 1XNQE 4MU1A 3F0NA 2PNZB 1DARA 2E5LI 2IOPA 2VQEI 2BA1G 1Y4SA 4KQVA 3L7ZA 2OI2A 4UT4A 3M7ND 4DV3I 1USVA 4YY3E 3CDJA 1R6LA 2X36A 4MQYA 4FW5A 4X64I 2UUCE 4XTJA 4LFBI 2PO1A 4GQUA 3J7AM 3LNUA 3WU4A 4DR7I 4Z7CA 3HULA 1EI1A 3K17A 2GS8A 2Z5CB 5ELWA 4X64E 4DV2E 5EKWA 4PU9A 3OTOI 3M7NG 4OO1B 2Q2EB 1KIJA 2UUBE 4HY1A 1FJGI 1N33E 1H7UA 1E3HA 4X62E 4LCFA 4P52A 4B3TI 4LFAE 1Z0CA 4NXME 2UXCI 5DRRA 4AQYE 3WU6A 2HFSA 5C0XA 2PO0A 2Z5BA 4MU3A 4OX9I 2F4VE 1FWKA
chains in the Genus database with same CATH topology
2F1DA 4QNKA 1RHYA 5EL9A 5ELWA 4GQUA 4MU1A 4LOMA 5DNLA 2AE8A 4MU0A 4MU3A 5EKWA 4MU4A 5DNXA 4QNJA 4LPFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2F1D A;  4QNK A;  1RHY A;  5EL9 A;  5ELW A;  4GQU A;  4MU1 A;  4LOM A;  5DNL A;  2AE8 A;  4MU0 A;  4MU3 A;  5EKW A;  4MU4 A;  5DNX A;  4QNJ A;  4LPF A; 
#chains in the Genus database with same CATH topology
 1RRE A;  2VES A;  1N34 E;  4AID A;  3V2U C;  4NXN I;  4GKJ I;  1RHY A;  5C0X B;  2Z5B B;  3CWV A;  4JI6 E;  4N3O A;  4USK A;  5DNX A;  4KHP I;  1FKA E;  2V34 A;  4GKK E;  4NXN E;  4FW4 A;  3QT7 A;  1OYP A;  4FWG A;  3B82 A;  5L3J A;  4BA2 B;  4DR2 I;  4DR4 E;  1HNW E;  1ELO A;  3QT6 A;  3LPS A;  5IT9 C;  4DPU A;  2VF3 A;  2HK3 A;  4I3H A;  4DV7 I;  4LF8 E;  4DR2 E;  4IS9 A;  4IFD A;  2JEA B;  1U2R A;  4WUC A;  1PIE A;  2HHH I;  3M85 D;  1OYS A;  4JI8 I;  2GQ0 A;  3T1Y I;  1KVK A;  4DPX A;  4DV6 E;  4UTG A;  4EMD A;  1HNX E;  4AIM A;  2UXB I;  2AE8 A;  4ED4 A;  3GME A;  1XMQ I;  4JI0 E;  3T1Y E;  3P3C A;  4JI7 E;  4DUZ E;  4FW6 A;  4X65 I;  1H73 A;  2UXB E;  4LF9 I;  2C39 A;  3M85 G;  1IBM I;  4PRX A;  3PS1 A;  2VQF E;  2F1D A;  1PVG A;  3PYD A;  1Z0G A;  1UDO A;  1N36 I;  3ZKB A;  4JYA I;  1NHJ A;  2V8P A;  4FWD A;  3Q6M A;  2J65 A;  4OKG A;  3CDI A;  2UXD I;  4LOM A;  4X66 I;  3DD6 A;  3K1J A;  1Z0E A;  5C0X D;  4LCG A;  4B3R I;  1ZM9 A;  1Y6Z A;  3K85 A;  4X66 E;  4YY3 I;  5JEA C;  1B63 A;  1ZXM A;  4OO1 F;  1P42 A;  1QZR A;  4B3R E;  2HFU A;  1N0U A;  2UUC I;  1VIS A;  2WNR A;  4JG4 A;  2A2D A;  2UU9 E;  4RPF A;  3H1C A;  1S16 A;  4HYM A;  2WW4 A;  5JEA E;  4DV2 I;  3Q6N A;  4DV0 E;  4B3M I;  4WUB A;  4IFD C;  2BA0 D;  3L7Z B;  4WUD A;  4DUY I;  2UUB I;  3WU3 A;  3ZZT A;  1N33 I;  4B3M E;  4X62 I;  4DXL A;  4DUY E;  4IFD D;  2V2V A;  1OJ4 A;  2PO1 B;  3KRN A;  4LFA I;  4NXM I;  5C0X F;  4IFD E;  4AQY I;  4JI2 E;  4JI3 E;  1KKH A;  3LTO A;  2NN6 C;  2F4V I;  1HNZ I;  2BA0 G;  4QNJ A;  4USM A;  3ZM7 A;  1HK7 A;  5A2Q C;  4LF5 E;  2Z5E A;  5BR8 I;  1N34 I;  1FNM A;  3B4T A;  1HNZ E;  3U1K A;  2NN6 D;  4JI6 I;  3J80 C;  2NN6 E;  4J3D A;  5BR8 E;  4GKK I;  2PO0 B;  1N32 I;  4DPT A;  1IBL E;  3GCM A;  4URL A;  2BM1 A;  1WUU A;  1HNW I;  4DR4 I;  1XXE A;  5FLX Q;  1VI7 A;  2CZ9 A;  2JEB A;  5JEA A;  4DR3 E;  3JAM Q;  1UEK A;  1N32 E;  4IFD F;  2GO3 A;  4IZK A;  4LF8 I;  1R6M A;  2PNL A;  3B8H A;  1XMO E;  1E3P A;  1H72 C;  5JEA B;  3ZZU A;  3GON A;  5DRQ A;  5LMU E;  4DV6 I;  4IZK B;  1HNX I;  1Z0B A;  4LFC I;  2EFG A;  2LJP A;  4JI0 I;  1S4E A;  2ZM6 I;  4LF7 I;  4QNK A;  1EA6 A;  4JI7 I;  4DUZ I;  4DU7 A;  4IZJ A;  4LFC E;  4IFD B;  2CG9 A;  1Z0T A;  2UUA I;  2C37 A;  5DNL A;  2ZM6 E;  4LF7 E;  1MX0 A;  2VQF I;  2NN6 A;  1MG7 A;  1I94 I;  4YHH I;  1FI4 A;  2WP8 A;  4DV4 E;  1RR9 A;  2UUA E;  1MU5 A;  2J7K A;  4HAC A;  2V2Z A;  4ZVI A;  2C37 B;  2JE6 A;  1USU A;  4YHH E;  1I94 E;  4FW7 A;  2NN6 B;  2C39 B;  3U1Y A;  3UHM A;  3PYG A;  3J7A G;  5K36 A;  2C38 A;  1ZM2 A;  4DR6 E;  4JI5 I;  3P06 A;  3PS2 A;  3PRY A;  4DU8 A;  1N0V C;  4JI1 E;  4JI5 E;  2AJ4 A;  2E1R A;  2ZIT A;  3J81 Q;  1J5E I;  4FN5 A;  1K47 A;  4HXZ A;  5EL9 A;  2UU9 I;  1HR0 I;  1A6F A;  4DR5 I;  1Y4U A;  3P76 A;  3PYE A;  3PS3 A;  4U3B A;  1J5E E;  4U3D A;  4DV0 I;  1HR0 E;  1H7S A;  4DR5 E;  3T1H I;  5JEA D;  1OYR A;  1PKP A;  4MU0 A;  2HKJ A;  3P3E A;  2O1T A;  2R3V A;  2WNR B;  3T1H E;  3P3G A;  5DRO A;  3QT8 A;  4FW9 A;  3D4J A;  4JI4 I;  4JI2 I;  4K0K E;  1Z59 A;  4JI3 I;  4OZE A;  5DRP A;  2PNM A;  3WU5 A;  1KTV A;  2CVE A;  4DPW A;  2Z5C A;  4LF5 I;  2E5L E;  4JI4 E;  2VQE E;  2HK2 A;  2CGE A;  4PRV A;  4OO1 A;  3HKM A;  4MDT A;  5IT9 Q;  1ZM4 A;  4IZJ D;  4DV3 E;  1NZ0 A;  2O3Z A;  2BM0 A;  4DPY A;  1BKN A;  2PO2 A;  3H4L A;  4LFB E;  2BV3 A;  4DR1 I;  4BA1 A;  1IBL I;  2IES A;  5JEA F;  4DR7 E;  4Z7Y A;  5K36 C;  1UDS A;  1Z5C A;  3J81 C;  4DR3 I;  3NZK A;  4DR1 E;  3OTO E;  1NHI A;  2PO2 B;  2NPF A;  1XNR I;  4BA1 B;  5K36 D;  1XMO I;  4FW3 A;  5GMD A;  4DV5 I;  1FJG E;  5K36 E;  2XEX A;  2V2Q A;  4B3T E;  4MU4 A;  1XNR E;  5LMU I;  3HJC A;  2UXC E;  3ZZ0 A;  4DV5 E;  1Y5Y A;  2JEB B;  1IBK I;  2JT2 A;  4OX9 E;  4BA2 A;  4NBQ A;  3B78 A;  4LF4 I;  1ZM3 A;  4AM3 A;  1D6T A;  4M1K A;  3QT5 A;  1IBK E;  1B62 A;  4GKJ E;  2NN6 F;  5LL6 R;  4JV5 I;  4B3S I;  4LF4 E;  2JEA A;  2O1V A;  2O1W A;  4ISA A;  1H74 A;  4KHP E;  4DV4 I;  3Q1Q A;  1ZXN A;  4LCH A;  4JV5 E;  2A2C A;  4B3S E;  3M6A A;  5K36 F;  4IZJ B;  1UDQ A;  1FWL A;  1Z0W A;  1UDN A;  2O1U A;  4DR6 I;  3ZKD A;  4DV7 E;  4OO1 C;  2BR2 A;  2HKE A;  2WP8 B;  2HHH E;  5GME A;  4JI1 I;  4JI8 E;  1XHK A;  2DEJ A;  4HAC B;  2ZBK B;  5IWA I;  5FLX C;  4OO1 D;  2JE6 B;  2IER A;  4OO1 E;  2BR2 B;  2X7I A;  3JAM C;  3GLL A;  3V5R A;  4DV1 I;  1YHC A;  1XMQ E;  1YH8 A;  4P7A A;  5K36 B;  5IWA E;  2C38 B;  2R42 A;  4X65 E;  4MYT A;  1Z5A A;  4R1F A;  4LF6 I;  4LF9 E;  4LPF A;  1NHH A;  4DV1 E;  1Z0V A;  2GO4 A;  4FWH A;  5FWK A;  1IBM E;  5C0X C;  1Y60 A;  4LF6 E;  2DEI A;  2BA1 D;  3PYF A;  5A2Q Q;  5LMN I;  2IOQ A;  2PNZ A;  1XNQ I;  3J80 Q;  1N36 E;  1Z5B A;  4JYA E;  4K0K I;  5C0X E;  4MYU A;  5LMN E;  2UXD E;  1XNQ E;  4MU1 A;  3F0N A;  2PNZ B;  1DAR A;  2E5L I;  2IOP A;  2VQE I;  2BA1 G;  1Y4S A;  4KQV A;  3L7Z A;  2OI2 A;  4UT4 A;  3M7N D;  4DV3 I;  1USV A;  4YY3 E;  3CDJ A;  1R6L A;  2X36 A;  4MQY A;  4FW5 A;  4X64 I;  2UUC E;  4XTJ A;  4LFB I;  2PO1 A;  4GQU A;  3J7A M;  3LNU A;  3WU4 A;  4DR7 I;  4Z7C A;  3HUL A;  1EI1 A;  3K17 A;  2GS8 A;  2Z5C B;  5ELW A;  4X64 E;  4DV2 E;  5EKW A;  4PU9 A;  3OTO I;  3M7N G;  4OO1 B;  2Q2E B;  1KIJ A;  2UUB E;  4HY1 A;  1FJG I;  1N33 E;  1H7U A;  1E3H A;  4X62 E;  4LCF A;  4P52 A;  4B3T I;  4LFA E;  1Z0C A;  4NXM E;  2UXC I;  5DRR A;  4AQY E;  3WU6 A;  2HFS A;  5C0X A;  2PO0 A;  2Z5B A;  4MU3 A;  4OX9 I;  2F4V E;  1FWK A; 
#chains in the Genus database with same CATH homology
 2F1D A;  4QNK A;  1RHY A;  5EL9 A;  5ELW A;  4GQU A;  4MU1 A;  4LOM A;  5DNL A;  2AE8 A;  4MU0 A;  4MU3 A;  5EKW A;  4MU4 A;  5DNX A;  4QNJ A;  4LPF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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