5DRPA

Structure of the aalpxc/lpc-023 complex
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Drug design from the cryptic inhibitor envelope.
pubmed doi rcsb
source organism Aquifex aeolicus (strain vf5)
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 92
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2015-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 5drpA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 5drpA02
4MDTA 2VESA 3PS2A 4FW6A 1P42A 2IESA 4U3BA 1YHCA 3P3GA 1XXEA 2O3ZA 4J3DA 4IS9A 3UHMA 3PS1A 2IERA 4FW4A 4LCGA 4MQYA 3P3EA 4FW3A 4LCHA 3P3CA 4FW5A 5DROA 4U3DA 1YH8A 5DRPA 4OZEA 2GO3A 2J65A 2JT2A 5DRRA 4OKGA 2GO4A 3P76A 3NZKA 4ISAA 3PS3A 3U1YA 5DRQA 4FW7A 4LCFA
chains in the Genus database with same CATH superfamily
4NXNE 1IBKI 1WUUA 4ED4A 4YHHI 4DR1I 3M85D 1KVKA 2O1WA 3GCMA 4OO1E 1Z0EA 4USMA 4NXNI 4LFBE 1N33I 1DARA 4GKJI 4MQYA 3M7ND 4JI7E 2ZM6I 4HXZA 2HK2A 1Z5AA 3LPSA 1RHYA 2JE6A 1UDNA 2JEBA 2BM0A 1YH8A 3ZZ0A 5FWKA 4DV0E 1OYRA 3GLLA 3L7ZB 4LFCE 2C39B 2Z5BA 3PS3A 4DV6E 4FW7A 4LPFA 2Z5EA 3M85G 1OYPA 4BA1B 3V5RA 3JAMC 1XMOI 4FW4A 1IBME 4LF4I 4OO1A 2UU9I 1PVGA 3P06A 2V2QA 2PNLA 2HK3A 4AIMA 4DPUA 4DR6E 2V8PA 4FW9A 4LCHA 2DEJA 2PO1B 3B78A 2C39A 3WU4A 1XNRE 4LF9E 3PYEA 4GKKE 5A2QC 2V2VA 3H1CA 1PKPA 4B3RE 1HNWI 1USUA 1HK7A 5IWAE 4AIDA 2IOQA 3LTOA 2NN6B 3ZKDA 1NHIA 2UUAE 2A2CA 4JI0E 2IOPA 2PO2A 4PU9A 1ELOA 1Y4SA 5K36F 4JI0I 2UUAI 3M6AA 3LNUA 4DV3I 4P52A 4JG4A 2Z5CA 2HFSA 3B4TA 1ZM3A 5C0XA 3U1KA 4KQVA 3J81Q 5JEAC 4DR5E 4DR1E 5K36B 1H74A 1MX0A 2PO2B 2V2ZA 5GMEA 2IESA 1OJ4A 1ZXNA 4OX9I 2O3ZA 4DU7A 4IFDE 4URLA 4LF5I 3K17A 5C0XB 5K36E 4JV5E 4JI8E 4LFBI 4U3DA 4LF5E 4IZKB 2C38B 2ZITA 1N32E 4X66I 4X65E 5A2QQ 4P7AA 5C0XE 1Z0BA 4USKA 5LMNE 4Z7YA 3PYDA 2Z5BB 2UU9E 4LFCI 4LF8E 4IFDC 5JEAA 5LMNI 1Z0CA 2HKEA 2PNZB 1OYSA 1IBLI 4BA1A 2WNRB 2ZBKB 2R3VA 3CDIA 3ZM7A 3HULA 1XNRI 4JI1I 5FLXC 1XMOE 3P3CA 4LF4E 3L7ZA 1XNQI 2NPFA 2HKJA 2Q2EB 1J5EE 4JI1E 1XMQI 1PIEA 2JT2A 4OKGA 1B63A 5IWAI 5DNXA 4B3TI 4DPYA 2CG9A 4DU8A 2UUCE 4MYUA 5FLXQ 4PRXA 3K1JA 4B3RI 1HNWE 5JEAE 2UUCI 4FN5A 2CVEA 4WUBA 5C0XD 3F0NA 4DV1E 1R6MA 3QT7A 1N0VC 2J65A 3P76A 5L3JA 2E5LI 4LCFA 3PS2A 2GQ0A 5K36A 1N36I 2IERA 2O1TA 4MU0A 5JEAB 1S16A 3P3EA 2HFUA 4MYTA 1N36E 2BM1A 3PYGA 4JI3I 4IFDD 3KRNA 4JV5I 2NN6C 2JEBB 1UDQA 4JI8I 4MU1A 2CGEA 2AJ4A 3T1YE 4JI3E 4K0KE 4DR7E 3HJCA 2PO1A 1N32I 4JYAE 4DR3I 2UUBE 1Z5BA 2C37B 2HHHE 2GS8A 5ELWA 1HNXI 1VISA 1ZM2A 4B3SE 4RPFA 4LOMA 4OO1F 2J7KA 1IBLE 1HNZI 5K36C 1XMQE 2NN6E 4B3TE 5DROA 4B3SI 4M1KA 1BKNA 2UXBE 4AQYE 4IZJD 1UDSA 1XHKA 1Y5YA 2F4VI 1EA6A 2WP8A 5C0XC 4DR2I 2UXBI 2BA1D 1UDOA 1YHCA 1N0UA 3P3GA 4DR2E 1XXEA 4J3DA 4DV4I 5JEAD 4NXMI 4DV2I 3OTOI 5LL6R 2CZ9A 3PRYA 1U2RA 5BR8I 4NXME 5JEAF 4IFDB 5DNLA 2JE6B 2WP8B 5BR8E 3QT5A 1USVA 4ISAA 1E3HA 4OX9E 2PO0A 4JI2I 3HKMA 3B8HA 3J81C 1FKAE 4U3BA 4MU3A 2O1VA 5EL9A 4LCGA 2PNZA 3ZZUA 4X65I 2WW4A 3T1HE 4PRVA 4HACB 3ZKBA 3QT6A 4DV5I 4DR7I 4K0KI 5DRPA 4ZVIA 2VQFI 4DXLA 3K85A 2O1UA 4DR3E 1H7UA 2UUBI 1Y4UA 4DPWA 4UTGA 4R1FA 3T1HI 1Z59A 4LFAE 3NZKA 2VQFE 3J7AG 1D6TA 1P42A 1FI4A 1FJGI 3PYFA 3CDJA 2C37A 1Z5CA 5EKWA 4DUZI 4JYAI 4DPTA 2BV3A 4KHPE 2R42A 2Z5CB 1FWLA 2HHHI 4LF7E 1XNQE 3J80C 1Z0TA 4AQYI 1IBKE 1J5EI 1RR9A 2V34A 4N3OA 2F4VE 1HNXE 3Q6MA 1KIJA 4LF6E 4GKJE 4LF7I 4OO1C 4JI5E 4FWGA 4B3ME 1HNZE 4DV7E 5DRRA 2XEXA 1KTVA 4FW6A 4UT4A 4DV7I 1EI1A 1NZ0A 4HYMA 3J80Q 2DEIA 3V2UC 4EMDA 2VQEI 4DV1I 3Q6NA 2NN6A 1N34I 4DV4E 2EFGA 4BA2A 4X62I 2BA0G 4QNJA 4Z7CA 1N34E 2E5LE 3OTOE 4XTJA 2UXDE 2BR2A 5K36D 1FNMA 1NHJA 5IT9C 2GO4A 1R6LA 4DUYI 3GMEA 2X36A 4WUCA 4I3HA 2OI2A 4YY3I 1I94E 4FWHA 4JI2E 4DV5E 4WUDA 3DD6A 3T1YI 4FW5A 4LFAI 1K47A 4DR4E 4NBQA 3WU5A 1MU5A 2NN6F 2VQEE 1HR0E 1ZXMA 4OZEA 2C38A 1FJGE 1Z0VA 2F1DA 4JI6E 5GMDA 4DUZE 1B62A 4IZKA 1HR0I 2UXCE 1H73A 1UEKA 1N33E 3M7NG 1E3PA 1Y60A 1Y6ZA 2ZM6E 3Q1QA 5LMUE 4IS9A 1S4EA 3PS1A 3UHMA 2JEAA 4LF6I 4FWDA 4JI4I 3H4LA 1A6FA 4QNKA 4JI5I 4YHHE 5LMUI 3B82A 4IZJA 4JI4E 4DV6I 4JI7I 4BA2B 3WU3A 5IT9Q 4IFDF 3U1YA 3QT8A 1H7SA 4DV0I 2NN6D 4X66E 4X64I 4B3MI 1H72C 2VESA 1IBMI 2BR2B 1FWKA 4DV2E 1RREA 1ZM4A 2WNRA 2X7IA 4X64E 4LF8I 4FW3A 2UXDI 2BA1G 4GKKI 2LJPA 3JAMQ 1QZRA 1VI7A 2A2DA 4DPXA 3J7AM 3ZZTA 4DR6I 4X62E 4HACA 3WU6A 1I94I 5DRQA 1Z0WA 4MDTA 4LF9I 1Z0GA 2PO0B 5C0XF 4OO1B 4DUYE 1MG7A 4IFDA 1NHHA 2PNMA 2AE8A 4HY1A 4YY3E 2E1RA 2BA0D 4DR5I 2JEAB 3CWVA 1KKHA 2VF3A 4MU4A 4JI6I 4OO1D 3D4JA 4AM3A 2UXCI 2GO3A 1ZM9A 4DR4I 4DV3E 3GONA 4IZJB 4GQUA 4KHPI
chains in the Genus database with same CATH topology
4MDTA 2VESA 3PS2A 4FW6A 1P42A 2IESA 4U3BA 1YHCA 3P3GA 1XXEA 2O3ZA 4J3DA 4IS9A 3UHMA 3PS1A 2IERA 4FW4A 4LCGA 4MQYA 3P3EA 4FW3A 4LCHA 3P3CA 4FW5A 5DROA 4U3DA 1YH8A 5DRPA 4OZEA 2GO3A 2J65A 2JT2A 5DRRA 4OKGA 2GO4A 3P76A 3NZKA 4ISAA 3PS3A 3U1YA 5DRQA 4FW7A 4LCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MDT A;  2VES A;  3PS2 A;  4FW6 A;  1P42 A;  2IES A;  4U3B A;  1YHC A;  3P3G A;  1XXE A;  2O3Z A;  4J3D A;  4IS9 A;  3UHM A;  3PS1 A;  2IER A;  4FW4 A;  4LCG A;  4MQY A;  3P3E A;  4FW3 A;  4LCH A;  3P3C A;  4FW5 A;  5DRO A;  4U3D A;  1YH8 A;  5DRP A;  4OZE A;  2GO3 A;  2J65 A;  2JT2 A;  5DRR A;  4OKG A;  2GO4 A;  3P76 A;  3NZK A;  4ISA A;  3PS3 A;  3U1Y A;  5DRQ A;  4FW7 A;  4LCF A; 
#chains in the Genus database with same CATH topology
 4NXN E;  1IBK I;  1WUU A;  4ED4 A;  4YHH I;  4DR1 I;  3M85 D;  1KVK A;  2O1W A;  3GCM A;  4OO1 E;  1Z0E A;  4USM A;  4NXN I;  4LFB E;  1N33 I;  1DAR A;  4GKJ I;  4MQY A;  3M7N D;  4JI7 E;  2ZM6 I;  4HXZ A;  2HK2 A;  1Z5A A;  3LPS A;  1RHY A;  2JE6 A;  1UDN A;  2JEB A;  2BM0 A;  1YH8 A;  3ZZ0 A;  5FWK A;  4DV0 E;  1OYR A;  3GLL A;  3L7Z B;  4LFC E;  2C39 B;  2Z5B A;  3PS3 A;  4DV6 E;  4FW7 A;  4LPF A;  2Z5E A;  3M85 G;  1OYP A;  4BA1 B;  3V5R A;  3JAM C;  1XMO I;  4FW4 A;  1IBM E;  4LF4 I;  4OO1 A;  2UU9 I;  1PVG A;  3P06 A;  2V2Q A;  2PNL A;  2HK3 A;  4AIM A;  4DPU A;  4DR6 E;  2V8P A;  4FW9 A;  4LCH A;  2DEJ A;  2PO1 B;  3B78 A;  2C39 A;  3WU4 A;  1XNR E;  4LF9 E;  3PYE A;  4GKK E;  5A2Q C;  2V2V A;  3H1C A;  1PKP A;  4B3R E;  1HNW I;  1USU A;  1HK7 A;  5IWA E;  4AID A;  2IOQ A;  3LTO A;  2NN6 B;  3ZKD A;  1NHI A;  2UUA E;  2A2C A;  4JI0 E;  2IOP A;  2PO2 A;  4PU9 A;  1ELO A;  1Y4S A;  5K36 F;  4JI0 I;  2UUA I;  3M6A A;  3LNU A;  4DV3 I;  4P52 A;  4JG4 A;  2Z5C A;  2HFS A;  3B4T A;  1ZM3 A;  5C0X A;  3U1K A;  4KQV A;  3J81 Q;  5JEA C;  4DR5 E;  4DR1 E;  5K36 B;  1H74 A;  1MX0 A;  2PO2 B;  2V2Z A;  5GME A;  2IES A;  1OJ4 A;  1ZXN A;  4OX9 I;  2O3Z A;  4DU7 A;  4IFD E;  4URL A;  4LF5 I;  3K17 A;  5C0X B;  5K36 E;  4JV5 E;  4JI8 E;  4LFB I;  4U3D A;  4LF5 E;  4IZK B;  2C38 B;  2ZIT A;  1N32 E;  4X66 I;  4X65 E;  5A2Q Q;  4P7A A;  5C0X E;  1Z0B A;  4USK A;  5LMN E;  4Z7Y A;  3PYD A;  2Z5B B;  2UU9 E;  4LFC I;  4LF8 E;  4IFD C;  5JEA A;  5LMN I;  1Z0C A;  2HKE A;  2PNZ B;  1OYS A;  1IBL I;  4BA1 A;  2WNR B;  2ZBK B;  2R3V A;  3CDI A;  3ZM7 A;  3HUL A;  1XNR I;  4JI1 I;  5FLX C;  1XMO E;  3P3C A;  4LF4 E;  3L7Z A;  1XNQ I;  2NPF A;  2HKJ A;  2Q2E B;  1J5E E;  4JI1 E;  1XMQ I;  1PIE A;  2JT2 A;  4OKG A;  1B63 A;  5IWA I;  5DNX A;  4B3T I;  4DPY A;  2CG9 A;  4DU8 A;  2UUC E;  4MYU A;  5FLX Q;  4PRX A;  3K1J A;  4B3R I;  1HNW E;  5JEA E;  2UUC I;  4FN5 A;  2CVE A;  4WUB A;  5C0X D;  3F0N A;  4DV1 E;  1R6M A;  3QT7 A;  1N0V C;  2J65 A;  3P76 A;  5L3J A;  2E5L I;  4LCF A;  3PS2 A;  2GQ0 A;  5K36 A;  1N36 I;  2IER A;  2O1T A;  4MU0 A;  5JEA B;  1S16 A;  3P3E A;  2HFU A;  4MYT A;  1N36 E;  2BM1 A;  3PYG A;  4JI3 I;  4IFD D;  3KRN A;  4JV5 I;  2NN6 C;  2JEB B;  1UDQ A;  4JI8 I;  4MU1 A;  2CGE A;  2AJ4 A;  3T1Y E;  4JI3 E;  4K0K E;  4DR7 E;  3HJC A;  2PO1 A;  1N32 I;  4JYA E;  4DR3 I;  2UUB E;  1Z5B A;  2C37 B;  2HHH E;  2GS8 A;  5ELW A;  1HNX I;  1VIS A;  1ZM2 A;  4B3S E;  4RPF A;  4LOM A;  4OO1 F;  2J7K A;  1IBL E;  1HNZ I;  5K36 C;  1XMQ E;  2NN6 E;  4B3T E;  5DRO A;  4B3S I;  4M1K A;  1BKN A;  2UXB E;  4AQY E;  4IZJ D;  1UDS A;  1XHK A;  1Y5Y A;  2F4V I;  1EA6 A;  2WP8 A;  5C0X C;  4DR2 I;  2UXB I;  2BA1 D;  1UDO A;  1YHC A;  1N0U A;  3P3G A;  4DR2 E;  1XXE A;  4J3D A;  4DV4 I;  5JEA D;  4NXM I;  4DV2 I;  3OTO I;  5LL6 R;  2CZ9 A;  3PRY A;  1U2R A;  5BR8 I;  4NXM E;  5JEA F;  4IFD B;  5DNL A;  2JE6 B;  2WP8 B;  5BR8 E;  3QT5 A;  1USV A;  4ISA A;  1E3H A;  4OX9 E;  2PO0 A;  4JI2 I;  3HKM A;  3B8H A;  3J81 C;  1FKA E;  4U3B A;  4MU3 A;  2O1V A;  5EL9 A;  4LCG A;  2PNZ A;  3ZZU A;  4X65 I;  2WW4 A;  3T1H E;  4PRV A;  4HAC B;  3ZKB A;  3QT6 A;  4DV5 I;  4DR7 I;  4K0K I;  5DRP A;  4ZVI A;  2VQF I;  4DXL A;  3K85 A;  2O1U A;  4DR3 E;  1H7U A;  2UUB I;  1Y4U A;  4DPW A;  4UTG A;  4R1F A;  3T1H I;  1Z59 A;  4LFA E;  3NZK A;  2VQF E;  3J7A G;  1D6T A;  1P42 A;  1FI4 A;  1FJG I;  3PYF A;  3CDJ A;  2C37 A;  1Z5C A;  5EKW A;  4DUZ I;  4JYA I;  4DPT A;  2BV3 A;  4KHP E;  2R42 A;  2Z5C B;  1FWL A;  2HHH I;  4LF7 E;  1XNQ E;  3J80 C;  1Z0T A;  4AQY I;  1IBK E;  1J5E I;  1RR9 A;  2V34 A;  4N3O A;  2F4V E;  1HNX E;  3Q6M A;  1KIJ A;  4LF6 E;  4GKJ E;  4LF7 I;  4OO1 C;  4JI5 E;  4FWG A;  4B3M E;  1HNZ E;  4DV7 E;  5DRR A;  2XEX A;  1KTV A;  4FW6 A;  4UT4 A;  4DV7 I;  1EI1 A;  1NZ0 A;  4HYM A;  3J80 Q;  2DEI A;  3V2U C;  4EMD A;  2VQE I;  4DV1 I;  3Q6N A;  2NN6 A;  1N34 I;  4DV4 E;  2EFG A;  4BA2 A;  4X62 I;  2BA0 G;  4QNJ A;  4Z7C A;  1N34 E;  2E5L E;  3OTO E;  4XTJ A;  2UXD E;  2BR2 A;  5K36 D;  1FNM A;  1NHJ A;  5IT9 C;  2GO4 A;  1R6L A;  4DUY I;  3GME A;  2X36 A;  4WUC A;  4I3H A;  2OI2 A;  4YY3 I;  1I94 E;  4FWH A;  4JI2 E;  4DV5 E;  4WUD A;  3DD6 A;  3T1Y I;  4FW5 A;  4LFA I;  1K47 A;  4DR4 E;  4NBQ A;  3WU5 A;  1MU5 A;  2NN6 F;  2VQE E;  1HR0 E;  1ZXM A;  4OZE A;  2C38 A;  1FJG E;  1Z0V A;  2F1D A;  4JI6 E;  5GMD A;  4DUZ E;  1B62 A;  4IZK A;  1HR0 I;  2UXC E;  1H73 A;  1UEK A;  1N33 E;  3M7N G;  1E3P A;  1Y60 A;  1Y6Z A;  2ZM6 E;  3Q1Q A;  5LMU E;  4IS9 A;  1S4E A;  3PS1 A;  3UHM A;  2JEA A;  4LF6 I;  4FWD A;  4JI4 I;  3H4L A;  1A6F A;  4QNK A;  4JI5 I;  4YHH E;  5LMU I;  3B82 A;  4IZJ A;  4JI4 E;  4DV6 I;  4JI7 I;  4BA2 B;  3WU3 A;  5IT9 Q;  4IFD F;  3U1Y A;  3QT8 A;  1H7S A;  4DV0 I;  2NN6 D;  4X66 E;  4X64 I;  4B3M I;  1H72 C;  2VES A;  1IBM I;  2BR2 B;  1FWK A;  4DV2 E;  1RRE A;  1ZM4 A;  2WNR A;  2X7I A;  4X64 E;  4LF8 I;  4FW3 A;  2UXD I;  2BA1 G;  4GKK I;  2LJP A;  3JAM Q;  1QZR A;  1VI7 A;  2A2D A;  4DPX A;  3J7A M;  3ZZT A;  4DR6 I;  4X62 E;  4HAC A;  3WU6 A;  1I94 I;  5DRQ A;  1Z0W A;  4MDT A;  4LF9 I;  1Z0G A;  2PO0 B;  5C0X F;  4OO1 B;  4DUY E;  1MG7 A;  4IFD A;  1NHH A;  2PNM A;  2AE8 A;  4HY1 A;  4YY3 E;  2E1R A;  2BA0 D;  4DR5 I;  2JEA B;  3CWV A;  1KKH A;  2VF3 A;  4MU4 A;  4JI6 I;  4OO1 D;  3D4J A;  4AM3 A;  2UXC I;  2GO3 A;  1ZM9 A;  4DR4 I;  4DV3 E;  3GON A;  4IZJ B;  4GQU A;  4KHP I; 
#chains in the Genus database with same CATH homology
 4MDT A;  2VES A;  3PS2 A;  4FW6 A;  1P42 A;  2IES A;  4U3B A;  1YHC A;  3P3G A;  1XXE A;  2O3Z A;  4J3D A;  4IS9 A;  3UHM A;  3PS1 A;  2IER A;  4FW4 A;  4LCG A;  4MQY A;  3P3E A;  4FW3 A;  4LCH A;  3P3C A;  4FW5 A;  5DRO A;  4U3D A;  1YH8 A;  5DRP A;  4OZE A;  2GO3 A;  2J65 A;  2JT2 A;  5DRR A;  4OKG A;  2GO4 A;  3P76 A;  3NZK A;  4ISA A;  3PS3 A;  3U1Y A;  5DRQ A;  4FW7 A;  4LCF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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