5DRPA

Structure of the aalpxc/lpc-023 complex
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Drug design from the cryptic inhibitor envelope.
pubmed doi rcsb
source organism Aquifex aeolicus (strain vf5)
molecule tags Hydrolase/hydrolase inhibitor
total genus 92
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2015-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 5drpA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 5drpA02
4MDTA 3P3EA 5DRQA 2O3ZA 4ISAA 4MQYA 4U3DA 4FW6A 4LCFA 2JT2A 3UHMA 3P3CA 4LCHA 2GO3A 3PS3A 1XXEA 4LCGA 1YH8A 3P76A 2GO4A 4FW4A 4U3BA 3P3GA 2IESA 1YHCA 2VESA 5DRPA 3PS2A 3U1YA 4FW5A 4IS9A 3NZKA 5DROA 2J65A 4J3DA 4OKGA 4OZEA 3PS1A 2IERA 5DRRA 4FW3A 4FW7A 1P42A
chains in the Genus database with same CATH superfamily
4JYAE 4B3RE 1ZXMA 1ZXNA 3B78A 4JI5I 1KKHA 5LMUE 3JAMQ 4DV7I 1U2RA 1HNXI 5K36F 3GONA 4OO1E 4DR1I 4LF8I 2Q2EB 4X64E 2NN6A 4IZKB 4OX9E 2EFGA 2ZM6I 4USKA 5DROA 4IFDF 4OKGA 1N34I 3PRYA 1FJGE 1IBKI 1K47A 1B63A 3Q6MA 4K0KE 1Y4UA 4YY3I 3J81Q 4ED4A 4U3DA 2UUAE 4JI5E 3U1KA 3KRNA 2UXBI 4LF4I 2O1VA 4DV7E 4BA2B 1HNXE 3P06A 2UXCI 2J7KA 5C0XB 3OTOI 1PKPA 1XMOI 3CDJA 4DR1E 2O1UA 2HHHE 2NN6D 3NZKA 4DPTA 4J3DA 3WU3A 1H72C 5LMNI 2PNLA 3DD6A 3ZZTA 2ZM6E 5K36C 3F0NA 1N34E 3J7AG 3PYGA 2CZ9A 2X36A 4DV6I 4UTGA 4JV5I 1Z59A 5LL6R 4IFDC 4YY3E 5JEAA 2V8PA 3ZZUA 4MU0A 4U3BA 2C39A 4DU8A 2PO1A 5DRPA 2PO2A 3LPSA 4NBQA 2UXBE 4LF4E 4WUDA 2F1DA 3J81C 2UXCE 3OTOE 2IOPA 1XMOE 4OZEA 2A2DA 1Y4SA 2DEJA 2IERA 3PYEA 1PVGA 5LMNE 2E5LI 3P3EA 5IT9C 5K36A 1WUUA 1FKAE 2BM0A 2V2QA 4AIDA 2GO3A 4DV6E 4DR4E 4GKKI 3HULA 4QNJA 4JI7I 4JV5E 2UUCI 1E3PA 2UXDE 1N0UA 2WW4A 3PS2A 1UEKA 1HK7A 4IFDA 3PYFA 4DV2I 4FW5A 1ZM4A 1S4EA 4LFCI 3V5RA 4DUYI 1XMQE 4KQVA 4ZVIA 4X65I 1H7UA 4HY1A 2E5LE 2HK3A 1XHKA 2BM1A 4AIMA 4P52A 4I3HA 5K36D 4LF5I 3QT6A 2BA1G 4GKJI 1Z0GA 4GKKE 4JI7E 4BA1A 2VQEI 2OI2A 1IBMI 2UUCE 5IWAI 3WU6A 3L7ZB 3QT7A 4IFDD 2BA1D 2CGEA 1NHIA 4MYTA 3J80Q 4DV1I 2VF3A 2VQFE 4DUYE 4JI1I 4X65E 5FLXQ 3QT5A 4RPFA 2PNMA 2IESA 1HNZE 1H74A 2PNZA 4DR2I 4LFAE 4GKJE 4IS9A 3T1HI 2HKEA 2BV3A 4HYMA 1KVKA 2VQEE 1IBME 5IWAE 4DUZI 4AQYI 2C38A 4DR6I 2IOQA 4NXMI 2NN6B 4DPWA 4DV1E 5A2QC 4LF6I 3CWVA 5JEAC 4DR5I 2V34A 4YHHI 4NXNI 4KHPI 4B3TI 1USVA 2GO4A 1EA6A 5GMDA 4OO1F 3B8HA 4LF8E 2C37A 4DR2E 3JAMC 3PS1A 4FW3A 3GMEA 3T1HE 1A6FA 1OYRA 2WNRA 4DUZE 1OYPA 1IBKE 4DR6E 4MQYA 3K85A 4NXME 3H1CA 1PIEA 4LCFA 2A2CA 1Z0CA 1ZM2A 4WUCA 4LF6E 1XXEA 4YHHE 4Z7CA 2Z5CA 1NHJA 1MX0A 4JI0I 4NXNE 4KHPE 1YHCA 4B3SI 1UDSA 2BR2A 4B3TE 4USMA 2JEAA 2HK2A 2CG9A 4DV5I 3ZM7A 1KIJA 5JEAB 2JEBA 1HR0I 1S16A 3H4LA 3ZKDA 2PO1B 2C39B 4DV0I 3T1YI 2PO2B 2UUBI 4LPFA 5C0XE 4P7AA 1IBLI 1OYSA 1UDNA 4OO1C 4FW6A 1N33I 3P3CA 4IZJA 3PS3A 4LCGA 1MU5A 3ZZ0A 4UT4A 3B4TA 1XNQI 4FW4A 5L3JA 2PO0A 2VESA 4MYUA 5JEAD 4JI0E 4DU7A 4DV4I 5K36B 4WUBA 4B3SE 1VI7A 5DRRA 4QNKA 3ZKBA 2WP8A 1RR9A 4DPXA 1R6MA 3HJCA 1Y5YA 4IFDB 1HR0E 1FWLA 5C0XF 4JI2I 4DV0E 2UUBE 3WU5A 5DNLA 1J5EI 2JT2A 3WU4A 4DXLA 1IBLE 4OO1A 1N33E 5ELWA 2JE6A 4IZJD 2V2ZA 4DPUA 4JI3I 4HACA 2Z5BA 3D4JA 1QZRA 2E1RA 4DV4E 1P42A 4DV2E 1EI1A 4X62I 4LFCE 4EMDA 5DRQA 4B3MI 4FWGA 1NZ0A 4BA1B 1Z0WA 4ISAA 1Y60A 4JI2E 5DNXA 1J5EE 3LTOA 4AM3A 3M7ND 4IFDE 3M85G 4LF5E 4OO1D 1FJGI 3U1YA 1OJ4A 2O1TA 5C0XC 3LNUA 1N36I 4R1FA 4K0KI 3QT8A 1KTVA 1I94I 4Z7YA 3CDIA 4FWDA 3M85D 2UUAI 4IZKA 3PYDA 2PNZB 2O3ZA 2R3VA 4MU3A 4X62E 2ZITA 1HNWI 4JI1E 3UHMA 4B3ME 2NPFA 4JI6I 3J80C 4GQUA 1USUA 2HHHI 2C38B 1H73A 4LF9I 1FNMA 2R42A 1Z5CA 2X7IA 5FLXC 2GS8A 4HXZA 2AE8A 5EKWA 4BA2A 1N36E 5C0XA 1VISA 2LJPA 2GQ0A 3HKMA 1I94E 2XEXA 1R6LA 1N32I 4AQYE 4N3OA 4LF7I 2C37B 4LFBI 1YH8A 4DR5E 1D6TA 1N0VC 1HNWE 5IT9Q 3P3GA 1XNRI 2DEIA 1RREA 4JI6E 2WNRB 2NN6E 4LF9E 4DR3I 2J65A 4MU4A 2HKJA 3K1JA 2Z5CB 4FN5A 4PRVA 3Q1QA 2BR2B 4DR4I 2JEAB 5C0XD 5BR8I 1Z0TA 4LOMA 2UXDI 1N32E 1Z5AA 5FWKA 2F4VI 1Z0VA 2Z5EA 2ZBKB 4MU1A 2JEBB 4LF7E 1E3HA 1BKNA 1XMQI 4LFBE 2NN6F 4DV3I 1XNRE 2AJ4A 3J7AM 4FWHA 4IZJB 2CVEA 1Y6ZA 1NHHA 4DV5E 4DR3E 1DARA 4JI4I 3GLLA 5GMEA 2PO0B 1UDQA 4X66I 2UU9I 4JG4A 3T1YE 4DR7I 2V2VA 1Z5BA 1ZM3A 5BR8E 1FI4A 1FWKA 2WP8B 5JEAE 2F4VE 4URLA 4JI8I 2BA0G 4XTJA 1MG7A 3V2UC 2HFUA 2O1WA 4OX9I 1UDOA 1XNQE 4FW9A 1RHYA 1B62A 2VQFI 4JYAI 3Q6NA 4B3RI 4DV3E 2BA0D 1ZM9A 4MDTA 4OO1B 5LMUI 3GCMA 2JE6B 3K17A 4JI4E 3L7ZA 4HACB 4X66E 2Z5BB 4DPYA 1HNZI 2UU9E 2NN6C 5K36E 3M7NG 4LCHA 4X64I 4LFAI 3P76A 4M1KA 5EL9A 1H7SA 4DR7E 2HFSA 5JEAF 1Z0BA 5A2QQ 4PU9A 1ELOA 3B82A 4JI8E 1Z0EA 4PRXA 4FW7A 4JI3E 3M6AA
chains in the Genus database with same CATH topology
4MDTA 3P3EA 5DRQA 2O3ZA 4ISAA 4MQYA 4U3DA 4FW6A 4LCFA 2JT2A 3UHMA 3P3CA 4LCHA 2GO3A 3PS3A 1XXEA 4LCGA 1YH8A 3P76A 2GO4A 4FW4A 4U3BA 3P3GA 2IESA 1YHCA 2VESA 5DRPA 3PS2A 3U1YA 4FW5A 4IS9A 3NZKA 5DROA 2J65A 4J3DA 4OKGA 4OZEA 3PS1A 2IERA 5DRRA 4FW3A 4FW7A 1P42A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MDT A;  3P3E A;  5DRQ A;  2O3Z A;  4ISA A;  4MQY A;  4U3D A;  4FW6 A;  4LCF A;  2JT2 A;  3UHM A;  3P3C A;  4LCH A;  2GO3 A;  3PS3 A;  1XXE A;  4LCG A;  1YH8 A;  3P76 A;  2GO4 A;  4FW4 A;  4U3B A;  3P3G A;  2IES A;  1YHC A;  2VES A;  5DRP A;  3PS2 A;  3U1Y A;  4FW5 A;  4IS9 A;  3NZK A;  5DRO A;  2J65 A;  4J3D A;  4OKG A;  4OZE A;  3PS1 A;  2IER A;  5DRR A;  4FW3 A;  4FW7 A;  1P42 A; 
#chains in the Genus database with same CATH topology
 4JYA E;  4B3R E;  1ZXM A;  1ZXN A;  3B78 A;  4JI5 I;  1KKH A;  5LMU E;  3JAM Q;  4DV7 I;  1U2R A;  1HNX I;  5K36 F;  3GON A;  4OO1 E;  4DR1 I;  4LF8 I;  2Q2E B;  4X64 E;  2NN6 A;  4IZK B;  4OX9 E;  2EFG A;  2ZM6 I;  4USK A;  5DRO A;  4IFD F;  4OKG A;  1N34 I;  3PRY A;  1FJG E;  1IBK I;  1K47 A;  1B63 A;  3Q6M A;  4K0K E;  1Y4U A;  4YY3 I;  3J81 Q;  4ED4 A;  4U3D A;  2UUA E;  4JI5 E;  3U1K A;  3KRN A;  2UXB I;  4LF4 I;  2O1V A;  4DV7 E;  4BA2 B;  1HNX E;  3P06 A;  2UXC I;  2J7K A;  5C0X B;  3OTO I;  1PKP A;  1XMO I;  3CDJ A;  4DR1 E;  2O1U A;  2HHH E;  2NN6 D;  3NZK A;  4DPT A;  4J3D A;  3WU3 A;  1H72 C;  5LMN I;  2PNL A;  3DD6 A;  3ZZT A;  2ZM6 E;  5K36 C;  3F0N A;  1N34 E;  3J7A G;  3PYG A;  2CZ9 A;  2X36 A;  4DV6 I;  4UTG A;  4JV5 I;  1Z59 A;  5LL6 R;  4IFD C;  4YY3 E;  5JEA A;  2V8P A;  3ZZU A;  4MU0 A;  4U3B A;  2C39 A;  4DU8 A;  2PO1 A;  5DRP A;  2PO2 A;  3LPS A;  4NBQ A;  2UXB E;  4LF4 E;  4WUD A;  2F1D A;  3J81 C;  2UXC E;  3OTO E;  2IOP A;  1XMO E;  4OZE A;  2A2D A;  1Y4S A;  2DEJ A;  2IER A;  3PYE A;  1PVG A;  5LMN E;  2E5L I;  3P3E A;  5IT9 C;  5K36 A;  1WUU A;  1FKA E;  2BM0 A;  2V2Q A;  4AID A;  2GO3 A;  4DV6 E;  4DR4 E;  4GKK I;  3HUL A;  4QNJ A;  4JI7 I;  4JV5 E;  2UUC I;  1E3P A;  2UXD E;  1N0U A;  2WW4 A;  3PS2 A;  1UEK A;  1HK7 A;  4IFD A;  3PYF A;  4DV2 I;  4FW5 A;  1ZM4 A;  1S4E A;  4LFC I;  3V5R A;  4DUY I;  1XMQ E;  4KQV A;  4ZVI A;  4X65 I;  1H7U A;  4HY1 A;  2E5L E;  2HK3 A;  1XHK A;  2BM1 A;  4AIM A;  4P52 A;  4I3H A;  5K36 D;  4LF5 I;  3QT6 A;  2BA1 G;  4GKJ I;  1Z0G A;  4GKK E;  4JI7 E;  4BA1 A;  2VQE I;  2OI2 A;  1IBM I;  2UUC E;  5IWA I;  3WU6 A;  3L7Z B;  3QT7 A;  4IFD D;  2BA1 D;  2CGE A;  1NHI A;  4MYT A;  3J80 Q;  4DV1 I;  2VF3 A;  2VQF E;  4DUY E;  4JI1 I;  4X65 E;  5FLX Q;  3QT5 A;  4RPF A;  2PNM A;  2IES A;  1HNZ E;  1H74 A;  2PNZ A;  4DR2 I;  4LFA E;  4GKJ E;  4IS9 A;  3T1H I;  2HKE A;  2BV3 A;  4HYM A;  1KVK A;  2VQE E;  1IBM E;  5IWA E;  4DUZ I;  4AQY I;  2C38 A;  4DR6 I;  2IOQ A;  4NXM I;  2NN6 B;  4DPW A;  4DV1 E;  5A2Q C;  4LF6 I;  3CWV A;  5JEA C;  4DR5 I;  2V34 A;  4YHH I;  4NXN I;  4KHP I;  4B3T I;  1USV A;  2GO4 A;  1EA6 A;  5GMD A;  4OO1 F;  3B8H A;  4LF8 E;  2C37 A;  4DR2 E;  3JAM C;  3PS1 A;  4FW3 A;  3GME A;  3T1H E;  1A6F A;  1OYR A;  2WNR A;  4DUZ E;  1OYP A;  1IBK E;  4DR6 E;  4MQY A;  3K85 A;  4NXM E;  3H1C A;  1PIE A;  4LCF A;  2A2C A;  1Z0C A;  1ZM2 A;  4WUC A;  4LF6 E;  1XXE A;  4YHH E;  4Z7C A;  2Z5C A;  1NHJ A;  1MX0 A;  4JI0 I;  4NXN E;  4KHP E;  1YHC A;  4B3S I;  1UDS A;  2BR2 A;  4B3T E;  4USM A;  2JEA A;  2HK2 A;  2CG9 A;  4DV5 I;  3ZM7 A;  1KIJ A;  5JEA B;  2JEB A;  1HR0 I;  1S16 A;  3H4L A;  3ZKD A;  2PO1 B;  2C39 B;  4DV0 I;  3T1Y I;  2PO2 B;  2UUB I;  4LPF A;  5C0X E;  4P7A A;  1IBL I;  1OYS A;  1UDN A;  4OO1 C;  4FW6 A;  1N33 I;  3P3C A;  4IZJ A;  3PS3 A;  4LCG A;  1MU5 A;  3ZZ0 A;  4UT4 A;  3B4T A;  1XNQ I;  4FW4 A;  5L3J A;  2PO0 A;  2VES A;  4MYU A;  5JEA D;  4JI0 E;  4DU7 A;  4DV4 I;  5K36 B;  4WUB A;  4B3S E;  1VI7 A;  5DRR A;  4QNK A;  3ZKB A;  2WP8 A;  1RR9 A;  4DPX A;  1R6M A;  3HJC A;  1Y5Y A;  4IFD B;  1HR0 E;  1FWL A;  5C0X F;  4JI2 I;  4DV0 E;  2UUB E;  3WU5 A;  5DNL A;  1J5E I;  2JT2 A;  3WU4 A;  4DXL A;  1IBL E;  4OO1 A;  1N33 E;  5ELW A;  2JE6 A;  4IZJ D;  2V2Z A;  4DPU A;  4JI3 I;  4HAC A;  2Z5B A;  3D4J A;  1QZR A;  2E1R A;  4DV4 E;  1P42 A;  4DV2 E;  1EI1 A;  4X62 I;  4LFC E;  4EMD A;  5DRQ A;  4B3M I;  4FWG A;  1NZ0 A;  4BA1 B;  1Z0W A;  4ISA A;  1Y60 A;  4JI2 E;  5DNX A;  1J5E E;  3LTO A;  4AM3 A;  3M7N D;  4IFD E;  3M85 G;  4LF5 E;  4OO1 D;  1FJG I;  3U1Y A;  1OJ4 A;  2O1T A;  5C0X C;  3LNU A;  1N36 I;  4R1F A;  4K0K I;  3QT8 A;  1KTV A;  1I94 I;  4Z7Y A;  3CDI A;  4FWD A;  3M85 D;  2UUA I;  4IZK A;  3PYD A;  2PNZ B;  2O3Z A;  2R3V A;  4MU3 A;  4X62 E;  2ZIT A;  1HNW I;  4JI1 E;  3UHM A;  4B3M E;  2NPF A;  4JI6 I;  3J80 C;  4GQU A;  1USU A;  2HHH I;  2C38 B;  1H73 A;  4LF9 I;  1FNM A;  2R42 A;  1Z5C A;  2X7I A;  5FLX C;  2GS8 A;  4HXZ A;  2AE8 A;  5EKW A;  4BA2 A;  1N36 E;  5C0X A;  1VIS A;  2LJP A;  2GQ0 A;  3HKM A;  1I94 E;  2XEX A;  1R6L A;  1N32 I;  4AQY E;  4N3O A;  4LF7 I;  2C37 B;  4LFB I;  1YH8 A;  4DR5 E;  1D6T A;  1N0V C;  1HNW E;  5IT9 Q;  3P3G A;  1XNR I;  2DEI A;  1RRE A;  4JI6 E;  2WNR B;  2NN6 E;  4LF9 E;  4DR3 I;  2J65 A;  4MU4 A;  2HKJ A;  3K1J A;  2Z5C B;  4FN5 A;  4PRV A;  3Q1Q A;  2BR2 B;  4DR4 I;  2JEA B;  5C0X D;  5BR8 I;  1Z0T A;  4LOM A;  2UXD I;  1N32 E;  1Z5A A;  5FWK A;  2F4V I;  1Z0V A;  2Z5E A;  2ZBK B;  4MU1 A;  2JEB B;  4LF7 E;  1E3H A;  1BKN A;  1XMQ I;  4LFB E;  2NN6 F;  4DV3 I;  1XNR E;  2AJ4 A;  3J7A M;  4FWH A;  4IZJ B;  2CVE A;  1Y6Z A;  1NHH A;  4DV5 E;  4DR3 E;  1DAR A;  4JI4 I;  3GLL A;  5GME A;  2PO0 B;  1UDQ A;  4X66 I;  2UU9 I;  4JG4 A;  3T1Y E;  4DR7 I;  2V2V A;  1Z5B A;  1ZM3 A;  5BR8 E;  1FI4 A;  1FWK A;  2WP8 B;  5JEA E;  2F4V E;  4URL A;  4JI8 I;  2BA0 G;  4XTJ A;  1MG7 A;  3V2U C;  2HFU A;  2O1W A;  4OX9 I;  1UDO A;  1XNQ E;  4FW9 A;  1RHY A;  1B62 A;  2VQF I;  4JYA I;  3Q6N A;  4B3R I;  4DV3 E;  2BA0 D;  1ZM9 A;  4MDT A;  4OO1 B;  5LMU I;  3GCM A;  2JE6 B;  3K17 A;  4JI4 E;  3L7Z A;  4HAC B;  4X66 E;  2Z5B B;  4DPY A;  1HNZ I;  2UU9 E;  2NN6 C;  5K36 E;  3M7N G;  4LCH A;  4X64 I;  4LFA I;  3P76 A;  4M1K A;  5EL9 A;  1H7S A;  4DR7 E;  2HFS A;  5JEA F;  1Z0B A;  5A2Q Q;  4PU9 A;  1ELO A;  3B82 A;  4JI8 E;  1Z0E A;  4PRX A;  4FW7 A;  4JI3 E;  3M6A A; 
#chains in the Genus database with same CATH homology
 4MDT A;  3P3E A;  5DRQ A;  2O3Z A;  4ISA A;  4MQY A;  4U3D A;  4FW6 A;  4LCF A;  2JT2 A;  3UHM A;  3P3C A;  4LCH A;  2GO3 A;  3PS3 A;  1XXE A;  4LCG A;  1YH8 A;  3P76 A;  2GO4 A;  4FW4 A;  4U3B A;  3P3G A;  2IES A;  1YHC A;  2VES A;  5DRP A;  3PS2 A;  3U1Y A;  4FW5 A;  4IS9 A;  3NZK A;  5DRO A;  2J65 A;  4J3D A;  4OKG A;  4OZE A;  3PS1 A;  2IER A;  5DRR A;  4FW3 A;  4FW7 A;  1P42 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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