1XXEA

Rdc refined solution structure of the aalpxc/tu-514 complex
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
268
structure length
268
Chain Sequence
b'LEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFCFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQKLT'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
molecule tags Hydrolase
source organism Aquifex aeolicus
publication title Refined Solution Structure of the LpxC-TU-514 Complex and pK(a) Analysis of an Active Site Histidine: Insights into the Mechanism and Inhibitor Design
pubmed doi rcsb
total genus 63
structure length 268
sequence length 268
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2004-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 1xxeA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 1xxeA02
3PS2A 3P3EA 3P3CA 4J3DA 4FW7A 5DROA 2VESA 5DRQA 4MQYA 1YH8A 3U1YA 4MDTA 4U3DA 5DRRA 4FW3A 4FW4A 3UHMA 4IS9A 3P76A 2GO4A 3PS3A 4OZEA 2O3ZA 2J65A 4U3BA 3NZKA 5DRPA 1P42A 3PS1A 2GO3A 4FW6A 2IESA 1YHCA 4OKGA 2JT2A 4FW5A 4ISAA 4LCHA 1XXEA 2IERA 4LCGA 3P3GA 4LCFA
chains in the Genus database with same CATH superfamily
4IZKA 1Z0WA 4P52A 1N33E 2VQFI 4IFDD 3J7AM 4DV3E 4JV5I 1H7SA 4DUZI 2WP8B 4JG4A 4MDTA 1H72C 3WU5A 1IBLE 1HNZE 3U1KA 3OTOI 2UUBE 2R3VA 1FKAE 5C0XE 2BM1A 5ELWA 5LMUE 1VISA 1ZM4A 4DV1E 2PNMA 4LFBE 4IFDC 3PYFA 4LOMA 4LCFA 4LFBI 5BR8E 1B63A 2UU9I 2O1VA 5FWKA 3QT6A 1XMQE 3GCMA 5K36D 4HXZA 2Z5BB 3CDIA 4PRXA 4B3MI 1Y4UA 1OYSA 3GONA 2PNZB 3M85G 4DR7E 2ZM6E 3QT8A 2VQFE 4X66I 2X7IA 4FW5A 4X66E 1D6TA 2ZM6I 3Q6NA 5LL6R 4JI8E 4LPFA 1NZ0A 2VF3A 1ELOA 4NBQA 3V2UC 3CWVA 5K36C 4OX9I 2PO2B 3PYDA 4U3DA 4JI3I 1PIEA 3WU6A 4QNJA 4JI4I 4BA2B 5BR8I 4DPTA 2O1UA 4MU4A 1ZM2A 1EA6A 1A6FA 4BA1A 4JI6E 4DV5E 1IBMI 2Q2EB 2JE6B 4DR2I 2JT2A 3H4LA 5LMUI 1MU5A 1XMOI 3LNUA 4Z7YA 4LFAE 4LF8I 5C0XB 4LFCI 4FN5A 4HYMA 4K0KI 4M1KA 4DPUA 5DROA 2C39B 4KHPE 4PU9A 5DRQA 2JEBB 3ZZTA 2C39A 2PO0B 4X64I 4DR1E 5JEAA 2GO4A 4LFCE 3WU3A 2PO1B 5K36A 1XNRE 2V2QA 2E5LE 4DUYE 4OO1D 4B3TI 4LF7I 1OJ4A 2IESA 1QZRA 1FJGE 1Z0CA 1N0VC 2JE6A 4B3TE 4ISAA 4DV5I 1IBME 2Z5CB 1UDNA 3P3EA 4J3DA 1RR9A 2BR2A 4JI3E 2BA1D 4DV0I 2BM0A 1YH8A 2X36A 3ZKDA 2HKEA 4FW4A 5DNXA 1Z5AA 5K36B 1Y6ZA 3NZKA 4ED4A 1U2RA 3J80Q 4FWHA 1XMOE 2F4VE 3L7ZB 5DNLA 4JI0E 3J7AG 5JEAC 4LF6I 2DEIA 5FLXQ 1Z0GA 2UXDE 4B3ME 1R6LA 3JAMQ 1XMQI 2UUCE 1S4EA 1HNXE 4MYUA 4QNKA 1WUUA 5JEAE 2BR2B 3L7ZA 4WUCA 3PS3A 1KVKA 3HULA 3D4JA 4GQUA 4WUDA 3ZZ0A 3CDJA 2Z5CA 2ZITA 4JI7E 5C0XF 4MU3A 4DV2I 1Y4SA 4LF6E 2IERA 1E3PA 4DPWA 2O1WA 1VI7A 3LPSA 1Z0EA 3LTOA 4DR4E 5JEAB 5A2QC 1IBLI 4OO1B 1N0UA 4DPYA 2CG9A 2HK3A 4DV7I 2NN6A 4DUZE 2UU9E 4URLA 5JEAF 4FWDA 2PNLA 4GKKE 3Q6MA 1NHHA 2O3ZA 4DV0E 3T1YE 2HK2A 4LF5I 1MG7A 2O1TA 2EFGA 3GMEA 4DU8A 4DR5E 4NXMI 4X65I 4DV4E 4JI2E 2BA1G 4JYAE 5EL9A 5FLXC 3OTOE 4P7AA 3P3CA 1RHYA 4BA2A 4YY3E 4FW7A 1XNRI 4JI5I 2C37A 5C0XC 4JV5E 3ZM7A 3P76A 4MYTA 3HJCA 1N33I 4GKJI 2GO3A 3ZKBA 3PRYA 2JEBA 4JYAI 1IBKE 3T1HI 3QT5A 4X65E 4DV4I 2HKJA 4JI6I 4HY1A 1UDQA 4DV2E 5IT9Q 2BA0G 4JI1E 4JI7I 2V2VA 2UUAI 3J81C 2PO1A 3F0NA 1UDSA 2UXCI 4MQYA 2PO0A 2NN6B 4DV7E 4IS9A 2UUCI 4OX9E 4OO1A 4DPXA 4WUBA 4DR3I 4IZJD 5L3JA 2GQ0A 4AM3A 2R42A 2IOQA 1PKPA 4N3OA 4BA1B 2E1RA 3DD6A 5A2QQ 4UTGA 1USVA 1ZM9A 2WP8A 1I94I 2J65A 1R6MA 4IFDE 4RPFA 1OYPA 5IT9C 3ZZUA 2BA0D 3M6AA 3H1CA 2UUAE 4FW6A 1N32I 1ZM3A 1HK7A 1XXEA 2AJ4A 3P3GA 3T1HE 3B8HA 3PYEA 3K85A 3PS2A 4OO1F 1Z0VA 4LF9I 1HNZI 1I94E 2E5LI 4HACB 4UT4A 1Z0TA 2Z5BA 4X64E 1KKHA 1Z59A 3UHMA 2A2CA 1N34E 3P06A 4JI5E 4MU0A 2HHHI 4K0KE 4I3HA 2JEAA 1S16A 4DV3I 1RREA 1YHCA 4OKGA 4R1FA 1Z0BA 4IZJA 4Z7CA 4JI2I 1H74A 2OI2A 2Z5EA 4XTJA 1BKNA 4AIDA 1Z5CA 1KIJA 3K1JA 4LF7E 4USMA 2WW4A 4B3RI 3QT7A 3B78A 5K36E 2V34A 1XNQE 3K17A 4GKKI 3V5RA 4DR1I 3J81Q 5DRRA 4X62I 4IFDA 1Y60A 2VQEI 1ZXNA 4OZEA 2NPFA 4DXLA 4DV6I 3Q1QA 2HFUA 2PNZA 4DR4I 1H73A 5C0XA 1HNWI 2CVEA 4IZJB 3B82A 4LF8E 4YHHE 2HHHE 5LMNE 3M85D 2C38B 2VESA 4DR6I 3M7ND 2CZ9A 1OYRA 2LJPA 4EMDA 4JI4E 2A2DA 4B3RE 1FWLA 4YY3I 4OO1E 2UXBI 2PO2A 2NN6E 1HNXI 4U3BA 3WU4A 5GMEA 5DRPA 4PRVA 4AIMA 4DR5I 2UXDI 4JI8I 4LCHA 1NHJA 4LF5E 1ZXMA 2DEJA 1H7UA 5EKWA 2J7KA 3GLLA 4MU1A 4DV1I 1N34I 1FNMA 4KQVA 4LF4E 2XEXA 3B4TA 5IWAI 1HR0I 4DR7I 2UUBI 2ZBKB 2BV3A 5IWAE 1HR0E 1E3HA 2V2ZA 4USKA 3JAMC 4LF9E 2F1DA 3KRNA 2CGEA 4LF4I 1P42A 2WNRA 1N32E 2IOPA 1UEKA 1Y5YA 1NHIA 1Z5BA 4HACA 1B62A 4LCGA 2NN6C 1USUA 1J5EE 2NN6F 2WNRB 4OO1C 5C0XD 1FWKA 1K47A 2UXBE 4IFDB 5K36F 4DU7A 4DR6E 4IFDF 4FW3A 4AQYI 1MX0A 4JI1I 4KHPI 4NXNI 4B3SI 3PYGA 2NN6D 4ZVIA 4JI0I 4IZKB 5GMDA 1EI1A 5LMNI 4LFAI 4FW9A 2F4VI 4DR3E 4YHHI 2AE8A 2JEAB 1FI4A 1DARA 2C38A 4DR2E 1HNWE 1UDOA 3J80C 2HFSA 4FWGA 4X62E 4DV6E 4B3SE 4NXNE 5JEAD 2C37B 2UXCE 1XNQI 3U1YA 2VQEE 1N36E 3HKMA 4AQYE 1KTVA 3M7NG 1N36I 1XHKA 2V8PA 2GS8A 4NXME 3PS1A 1IBKI 1FJGI 1PVGA 1J5EI 4DUYI 3T1YI 4GKJE
chains in the Genus database with same CATH topology
3PS2A 3P3EA 3P3CA 4J3DA 4FW7A 5DROA 2VESA 5DRQA 4MQYA 1YH8A 3U1YA 4MDTA 4U3DA 5DRRA 4FW3A 4FW4A 3UHMA 4IS9A 3P76A 2GO4A 3PS3A 4OZEA 2O3ZA 2J65A 4U3BA 3NZKA 5DRPA 1P42A 3PS1A 2GO3A 4FW6A 2IESA 1YHCA 4OKGA 2JT2A 4FW5A 4ISAA 4LCHA 1XXEA 2IERA 4LCGA 3P3GA 4LCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PS2 A;  3P3E A;  3P3C A;  4J3D A;  4FW7 A;  5DRO A;  2VES A;  5DRQ A;  4MQY A;  1YH8 A;  3U1Y A;  4MDT A;  4U3D A;  5DRR A;  4FW3 A;  4FW4 A;  3UHM A;  4IS9 A;  3P76 A;  2GO4 A;  3PS3 A;  4OZE A;  2O3Z A;  2J65 A;  4U3B A;  3NZK A;  5DRP A;  1P42 A;  3PS1 A;  2GO3 A;  4FW6 A;  2IES A;  1YHC A;  4OKG A;  2JT2 A;  4FW5 A;  4ISA A;  4LCH A;  1XXE A;  2IER A;  4LCG A;  3P3G A;  4LCF A; 
#chains in the Genus database with same CATH topology
 4IZK A;  1Z0W A;  4P52 A;  1N33 E;  2VQF I;  4IFD D;  3J7A M;  4DV3 E;  4JV5 I;  1H7S A;  4DUZ I;  2WP8 B;  4JG4 A;  4MDT A;  1H72 C;  3WU5 A;  1IBL E;  1HNZ E;  3U1K A;  3OTO I;  2UUB E;  2R3V A;  1FKA E;  5C0X E;  2BM1 A;  5ELW A;  5LMU E;  1VIS A;  1ZM4 A;  4DV1 E;  2PNM A;  4LFB E;  4IFD C;  3PYF A;  4LOM A;  4LCF A;  4LFB I;  5BR8 E;  1B63 A;  2UU9 I;  2O1V A;  5FWK A;  3QT6 A;  1XMQ E;  3GCM A;  5K36 D;  4HXZ A;  2Z5B B;  3CDI A;  4PRX A;  4B3M I;  1Y4U A;  1OYS A;  3GON A;  2PNZ B;  3M85 G;  4DR7 E;  2ZM6 E;  3QT8 A;  2VQF E;  4X66 I;  2X7I A;  4FW5 A;  4X66 E;  1D6T A;  2ZM6 I;  3Q6N A;  5LL6 R;  4JI8 E;  4LPF A;  1NZ0 A;  2VF3 A;  1ELO A;  4NBQ A;  3V2U C;  3CWV A;  5K36 C;  4OX9 I;  2PO2 B;  3PYD A;  4U3D A;  4JI3 I;  1PIE A;  3WU6 A;  4QNJ A;  4JI4 I;  4BA2 B;  5BR8 I;  4DPT A;  2O1U A;  4MU4 A;  1ZM2 A;  1EA6 A;  1A6F A;  4BA1 A;  4JI6 E;  4DV5 E;  1IBM I;  2Q2E B;  2JE6 B;  4DR2 I;  2JT2 A;  3H4L A;  5LMU I;  1MU5 A;  1XMO I;  3LNU A;  4Z7Y A;  4LFA E;  4LF8 I;  5C0X B;  4LFC I;  4FN5 A;  4HYM A;  4K0K I;  4M1K A;  4DPU A;  5DRO A;  2C39 B;  4KHP E;  4PU9 A;  5DRQ A;  2JEB B;  3ZZT A;  2C39 A;  2PO0 B;  4X64 I;  4DR1 E;  5JEA A;  2GO4 A;  4LFC E;  3WU3 A;  2PO1 B;  5K36 A;  1XNR E;  2V2Q A;  2E5L E;  4DUY E;  4OO1 D;  4B3T I;  4LF7 I;  1OJ4 A;  2IES A;  1QZR A;  1FJG E;  1Z0C A;  1N0V C;  2JE6 A;  4B3T E;  4ISA A;  4DV5 I;  1IBM E;  2Z5C B;  1UDN A;  3P3E A;  4J3D A;  1RR9 A;  2BR2 A;  4JI3 E;  2BA1 D;  4DV0 I;  2BM0 A;  1YH8 A;  2X36 A;  3ZKD A;  2HKE A;  4FW4 A;  5DNX A;  1Z5A A;  5K36 B;  1Y6Z A;  3NZK A;  4ED4 A;  1U2R A;  3J80 Q;  4FWH A;  1XMO E;  2F4V E;  3L7Z B;  5DNL A;  4JI0 E;  3J7A G;  5JEA C;  4LF6 I;  2DEI A;  5FLX Q;  1Z0G A;  2UXD E;  4B3M E;  1R6L A;  3JAM Q;  1XMQ I;  2UUC E;  1S4E A;  1HNX E;  4MYU A;  4QNK A;  1WUU A;  5JEA E;  2BR2 B;  3L7Z A;  4WUC A;  3PS3 A;  1KVK A;  3HUL A;  3D4J A;  4GQU A;  4WUD A;  3ZZ0 A;  3CDJ A;  2Z5C A;  2ZIT A;  4JI7 E;  5C0X F;  4MU3 A;  4DV2 I;  1Y4S A;  4LF6 E;  2IER A;  1E3P A;  4DPW A;  2O1W A;  1VI7 A;  3LPS A;  1Z0E A;  3LTO A;  4DR4 E;  5JEA B;  5A2Q C;  1IBL I;  4OO1 B;  1N0U A;  4DPY A;  2CG9 A;  2HK3 A;  4DV7 I;  2NN6 A;  4DUZ E;  2UU9 E;  4URL A;  5JEA F;  4FWD A;  2PNL A;  4GKK E;  3Q6M A;  1NHH A;  2O3Z A;  4DV0 E;  3T1Y E;  2HK2 A;  4LF5 I;  1MG7 A;  2O1T A;  2EFG A;  3GME A;  4DU8 A;  4DR5 E;  4NXM I;  4X65 I;  4DV4 E;  4JI2 E;  2BA1 G;  4JYA E;  5EL9 A;  5FLX C;  3OTO E;  4P7A A;  3P3C A;  1RHY A;  4BA2 A;  4YY3 E;  4FW7 A;  1XNR I;  4JI5 I;  2C37 A;  5C0X C;  4JV5 E;  3ZM7 A;  3P76 A;  4MYT A;  3HJC A;  1N33 I;  4GKJ I;  2GO3 A;  3ZKB A;  3PRY A;  2JEB A;  4JYA I;  1IBK E;  3T1H I;  3QT5 A;  4X65 E;  4DV4 I;  2HKJ A;  4JI6 I;  4HY1 A;  1UDQ A;  4DV2 E;  5IT9 Q;  2BA0 G;  4JI1 E;  4JI7 I;  2V2V A;  2UUA I;  3J81 C;  2PO1 A;  3F0N A;  1UDS A;  2UXC I;  4MQY A;  2PO0 A;  2NN6 B;  4DV7 E;  4IS9 A;  2UUC I;  4OX9 E;  4OO1 A;  4DPX A;  4WUB A;  4DR3 I;  4IZJ D;  5L3J A;  2GQ0 A;  4AM3 A;  2R42 A;  2IOQ A;  1PKP A;  4N3O A;  4BA1 B;  2E1R A;  3DD6 A;  5A2Q Q;  4UTG A;  1USV A;  1ZM9 A;  2WP8 A;  1I94 I;  2J65 A;  1R6M A;  4IFD E;  4RPF A;  1OYP A;  5IT9 C;  3ZZU A;  2BA0 D;  3M6A A;  3H1C A;  2UUA E;  4FW6 A;  1N32 I;  1ZM3 A;  1HK7 A;  1XXE A;  2AJ4 A;  3P3G A;  3T1H E;  3B8H A;  3PYE A;  3K85 A;  3PS2 A;  4OO1 F;  1Z0V A;  4LF9 I;  1HNZ I;  1I94 E;  2E5L I;  4HAC B;  4UT4 A;  1Z0T A;  2Z5B A;  4X64 E;  1KKH A;  1Z59 A;  3UHM A;  2A2C A;  1N34 E;  3P06 A;  4JI5 E;  4MU0 A;  2HHH I;  4K0K E;  4I3H A;  2JEA A;  1S16 A;  4DV3 I;  1RRE A;  1YHC A;  4OKG A;  4R1F A;  1Z0B A;  4IZJ A;  4Z7C A;  4JI2 I;  1H74 A;  2OI2 A;  2Z5E A;  4XTJ A;  1BKN A;  4AID A;  1Z5C A;  1KIJ A;  3K1J A;  4LF7 E;  4USM A;  2WW4 A;  4B3R I;  3QT7 A;  3B78 A;  5K36 E;  2V34 A;  1XNQ E;  3K17 A;  4GKK I;  3V5R A;  4DR1 I;  3J81 Q;  5DRR A;  4X62 I;  4IFD A;  1Y60 A;  2VQE I;  1ZXN A;  4OZE A;  2NPF A;  4DXL A;  4DV6 I;  3Q1Q A;  2HFU A;  2PNZ A;  4DR4 I;  1H73 A;  5C0X A;  1HNW I;  2CVE A;  4IZJ B;  3B82 A;  4LF8 E;  4YHH E;  2HHH E;  5LMN E;  3M85 D;  2C38 B;  2VES A;  4DR6 I;  3M7N D;  2CZ9 A;  1OYR A;  2LJP A;  4EMD A;  4JI4 E;  2A2D A;  4B3R E;  1FWL A;  4YY3 I;  4OO1 E;  2UXB I;  2PO2 A;  2NN6 E;  1HNX I;  4U3B A;  3WU4 A;  5GME A;  5DRP A;  4PRV A;  4AIM A;  4DR5 I;  2UXD I;  4JI8 I;  4LCH A;  1NHJ A;  4LF5 E;  1ZXM A;  2DEJ A;  1H7U A;  5EKW A;  2J7K A;  3GLL A;  4MU1 A;  4DV1 I;  1N34 I;  1FNM A;  4KQV A;  4LF4 E;  2XEX A;  3B4T A;  5IWA I;  1HR0 I;  4DR7 I;  2UUB I;  2ZBK B;  2BV3 A;  5IWA E;  1HR0 E;  1E3H A;  2V2Z A;  4USK A;  3JAM C;  4LF9 E;  2F1D A;  3KRN A;  2CGE A;  4LF4 I;  1P42 A;  2WNR A;  1N32 E;  2IOP A;  1UEK A;  1Y5Y A;  1NHI A;  1Z5B A;  4HAC A;  1B62 A;  4LCG A;  2NN6 C;  1USU A;  1J5E E;  2NN6 F;  2WNR B;  4OO1 C;  5C0X D;  1FWK A;  1K47 A;  2UXB E;  4IFD B;  5K36 F;  4DU7 A;  4DR6 E;  4IFD F;  4FW3 A;  4AQY I;  1MX0 A;  4JI1 I;  4KHP I;  4NXN I;  4B3S I;  3PYG A;  2NN6 D;  4ZVI A;  4JI0 I;  4IZK B;  5GMD A;  1EI1 A;  5LMN I;  4LFA I;  4FW9 A;  2F4V I;  4DR3 E;  4YHH I;  2AE8 A;  2JEA B;  1FI4 A;  1DAR A;  2C38 A;  4DR2 E;  1HNW E;  1UDO A;  3J80 C;  2HFS A;  4FWG A;  4X62 E;  4DV6 E;  4B3S E;  4NXN E;  5JEA D;  2C37 B;  2UXC E;  1XNQ I;  3U1Y A;  2VQE E;  1N36 E;  3HKM A;  4AQY E;  1KTV A;  3M7N G;  1N36 I;  1XHK A;  2V8P A;  2GS8 A;  4NXM E;  3PS1 A;  1IBK I;  1FJG I;  1PVG A;  1J5E I;  4DUY I;  3T1Y I;  4GKJ E; 
#chains in the Genus database with same CATH homology
 3PS2 A;  3P3E A;  3P3C A;  4J3D A;  4FW7 A;  5DRO A;  2VES A;  5DRQ A;  4MQY A;  1YH8 A;  3U1Y A;  4MDT A;  4U3D A;  5DRR A;  4FW3 A;  4FW4 A;  3UHM A;  4IS9 A;  3P76 A;  2GO4 A;  3PS3 A;  4OZE A;  2O3Z A;  2J65 A;  4U3B A;  3NZK A;  5DRP A;  1P42 A;  3PS1 A;  2GO3 A;  4FW6 A;  2IES A;  1YHC A;  4OKG A;  2JT2 A;  4FW5 A;  4ISA A;  4LCH A;  1XXE A;  2IER A;  4LCG A;  3P3G A;  4LCF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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