4FW7A

Crystal structure of the lpxc in complex with n-[(2s,3r)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide inhibitor
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
301
structure length
301
Chain Sequence
NAMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Crystal Structure of the LpxC
rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase/hydrolase inhibitor
total genus 93
structure length 301
sequence length 301
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2012-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4fw7A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4fw7A02
3PS3A 3U1YA 4MDTA 4IS9A 4U3DA 4OKGA 4FW7A 4LCHA 5DRPA 4FW6A 1XXEA 3NZKA 4U3BA 2O3ZA 1YH8A 2VESA 3P3CA 5DRQA 4FW5A 4LCFA 3P3EA 2GO4A 1YHCA 3UHMA 5DRRA 3PS1A 2IERA 2GO3A 3PS2A 2J65A 4J3DA 1P42A 4OZEA 2JT2A 3P3GA 3P76A 4ISAA 4FW3A 4MQYA 5DROA 4FW4A 4LCGA 2IESA
chains in the Genus database with same CATH superfamily
1NHJA 3KRNA 5LMUE 3PRYA 4IS9A 3ZKDA 1XNQE 4IFDD 2V2ZA 1XMQI 1UDQA 2PO1A 3PYEA 2O1VA 4B3SI 1K47A 4DV3I 1HR0I 4DV1I 5LL6R 2R3VA 1I94E 1VISA 4AIDA 4OO1E 2Z5BB 1Z0VA 1H73A 4JYAI 1ELOA 2GQ0A 4OZEA 3T1HE 2F1DA 2UUAE 5LMUI 4OO1D 4FWGA 1XNQI 4DR2I 3B78A 4X66E 2NN6C 2AJ4A 4USKA 4IZKA 2NN6A 3CWVA 1PKPA 1FI4A 4FW6A 3ZZTA 1I94I 1E3HA 4AIMA 1HNZE 4EMDA 2R42A 3QT6A 3J81Q 4N3OA 2Z5CB 3T1HI 4BA2B 2UUAI 4LOMA 1OYPA 2C39A 2JE6A 2UU9E 4LFCE 5DROA 2NN6E 4X66I 1KTVA 4OO1B 2HFUA 4DR7E 1Z0WA 1Z0TA 3B8HA 4LF4E 2JEAA 2NN6D 1S4EA 2A2DA 1HNZI 4ZVIA 4DR4I 1Z0CA 3PYDA 1Z5AA 5C0XF 2UU9I 1B62A 2J65A 4LFCI 1MX0A 1OYSA 2PNMA 3ZZ0A 2EFGA 2E1RA 4DR7I 2F4VE 1ZM3A 4LF4I 4JI6E 4MDTA 5GMEA 2V34A 4UTGA 3CDJA 5FLXQ 1D6TA 4IZKB 4DR6E 4DV5E 1Y5YA 2Z5BA 4MYUA 5GMDA 3K17A 2PNLA 4IFDF 2F4VI 2VF3A 1H74A 4B3RE 3QT8A 4JI6I 1Z0EA 4JI1E 3V2UC 1ZM2A 4OX9I 5IWAE 4DR6I 4XTJA 4DV5I 4FW9A 3WU3A 2VESA 2JEAB 1Y4UA 2Z5CA 4LCFA 1Y60A 3GONA 4J3DA 4MU3A 3F0NA 1NHIA 4DR5E 4B3RI 3J80C 5JEAC 2WNRB 4DPUA 3QT7A 1XNRE 4JI1I 4DR1E 4LFBI 5IWAI 4JI4E 1USUA 4BA1B 1U2RA 3WU6A 4LF7E 3GMEA 1ZM9A 2IOQA 4Z7CA 3LTOA 3WU4A 4B3TI 2BA1G 2V8PA 1B63A 4FWDA 2VQFE 4DR2E 2CGEA 3M6AA 3QT5A 3NZKA 1BKNA 5FWKA 3HKMA 1YHCA 4URLA 4DR5I 5DRRA 1Y6ZA 3B4TA 3WU5A 4DV4E 2CVEA 4IZJB 1XNRI 1EA6A 4DR1I 3B82A 4JI4I 1UDSA 2V2QA 4DV0E 4LF7I 1Z5CA 2IESA 3ZZUA 1MU5A 5C0XB 4UT4A 3GLLA 2VQFI 2J7KA 4GKJE 3Q6NA 4LCHA 4B3ME 1XXEA 4LF5E 4KHPE 2BR2B 5DRQA 4AQYE 3U1KA 2Z5EA 4DR4E 4DV4I 1EI1A 4LPFA 3JAMC 2BV3A 1N34I 1P42A 4DV0I 2PO2B 3Q1QA 4PRVA 4DV2I 4DV7E 4MYTA 4GKJI 1H7UA 4DUYE 4NXNE 4JV5E 3GCMA 1UEKA 5JEAB 4B3MI 2ZM6E 1NHHA 5K36F 4LF5I 4KHPI 4AQYI 1KVKA 3M85G 1HK7A 3CDIA 2HK2A 3PS1A 2DEIA 4HYMA 2WNRA 4DV7I 3M85D 2X7IA 4USMA 1Z5BA 1FWLA 2JT2A 4NXNI 3P76A 4MQYA 4DUYI 4JV5I 4BA1A 3LNUA 2UXCE 2ZM6I 4K0KE 4MU1A 4WUCA 4OKGA 3L7ZB 4LF8E 2CG9A 2HFSA 4OX9E 5L3JA 2BM1A 2LJPA 3H1CA 5EKWA 4QNJA 4IZJA 4YY3E 3LPSA 4X64E 4DPTA 2UXDE 5C0XC 2UXCI 2VQEE 1S16A 3ZM7A 4RPFA 5C0XA 4FW4A 4YHHE 4JI3E 4K0KI 3K1JA 2IOPA 3T1YE 4DR3E 4LF8I 3PYFA 1FNMA 4U3DA 2C38B 4LFBE 5A2QC 2BR2A 5EL9A 3P3CA 4B3TE 1Y4SA 3J80Q 1HNWE 4YY3I 1HNXE 3HULA 4X64I 5C0XE 2UXDI 2PO2A 4OO1F 2VQEI 4IZJD 1Z59A 4QNKA 4YHHI 4JI3I 1PIEA 2OI2A 3P3GA 4PRXA 4FW3A 1N32E 5C0XD 3DD6A 5JEAA 4DR3I 3T1YI 3V5RA 4P52A 4IFDC 2HKEA 2XEXA 4JI0E 1UDOA 1MG7A 4FW7A 1HNWI 1OJ4A 1HNXI 4JI8E 4WUDA 2ZITA 3P3EA 4KQVA 5LMNE 3UHMA 5K36B 2IERA 1Z0GA 2BA1D 5JEAE 1N32I 5IT9C 4GQUA 1DARA 4X62E 2NN6F 4JI0I 1N34E 3J7AM 5JEAD 2PNZB 4DV2E 1R6MA 4R1FA 3L7ZA 4JI8I 4DXLA 4U3BA 2O3ZA 3JAMQ 5LMNI 1H72C 1FJGE 1USVA 4DPYA 1QZRA 1N36E 1KKHA 1NZ0A 4X62I 1ZXNA 4HACB 2JEBB 1J5EE 4JI2E 4LCGA 2C37B 4DUZE 4ED4A 1IBME 1Z0BA 2C38A 2V2VA 2PO0B 4GKKE 2AE8A 2WW4A 4DPXA 4IFDB 1YH8A 1FJGI 4WUBA 5DNXA 1N36I 1RR9A 4DU8A 2GO4A 4JG4A 2UXBE 1KIJA 1XHKA 2GO3A 3PYGA 2WP8B 3Q6MA 1J5EI 4LF9E 1PVGA 4JI2I 4DUZI 1IBMI 2UUBE 2BM0A 4JI7E 3J81C 4GKKI 2Q2EB 4PU9A 4LF6E 3H4LA 2E5LE 5DRPA 1FWKA 3ZKBA 2NPFA 2UXBI 5K36C 1UDNA 2PO1B 3M7NG 5K36A 2DEJA 4LF9I 4HY1A 1RREA 4DV6E 1IBLE 2ZBKB 3D4JA 2UUBI 1ZM4A 4JI7I 2HHHE 4AM3A 4DU7A 4JI5E 2CZ9A 5BR8E 4LFAE 3M7ND 1N0VC 2PNZA 1XMOE 5A2QQ 4NXME 2HKJA 4FWHA 1H7SA 4LF6I 2E5LI 1E3PA 3HJCA 1IBKE 5K36E 4X65E 2X36A 4I3HA 2NN6B 4DV6I 4FW5A 1IBLI 5K36D 5FLXC 2HHHI 1N33E 2GS8A 4DPWA 5JEAF 1FKAE 3PS2A 4JI5I 4HACA 5BR8I 3OTOE 4LFAI 2JEBA 1XMOI 4MU4A 4NXMI 2C37A 5DNLA 2O1TA 2C39B 2JE6B 2PO0A 1RHYA 1IBKI 1WUUA 4X65I 3PS3A 2O1WA 3U1YA 4FN5A 3P06A 1N0UA 4IFDA 2UUCE 2O1UA 4Z7YA 4NBQA 4HXZA 1A6FA 2HK3A 1XMQE 1N33I 4P7AA 5IT9Q 1R6LA 4BA2A 1OYRA 4B3SE 2WP8A 4MU0A 3OTOI 4DV3E 2BA0G 3K85A 1HR0E 4DV1E 3J7AG 1VI7A 4OO1C 5ELWA 1ZXMA 4ISAA 4IFDE 4JYAE 2A2CA 4OO1A 2UUCI 4M1KA 2BA0D
chains in the Genus database with same CATH topology
3PS3A 3U1YA 4MDTA 4IS9A 4U3DA 4OKGA 4FW7A 4LCHA 5DRPA 4FW6A 1XXEA 3NZKA 4U3BA 2O3ZA 1YH8A 2VESA 3P3CA 5DRQA 4FW5A 4LCFA 3P3EA 2GO4A 1YHCA 3UHMA 5DRRA 3PS1A 2IERA 2GO3A 3PS2A 2J65A 4J3DA 1P42A 4OZEA 2JT2A 3P3GA 3P76A 4ISAA 4FW3A 4MQYA 5DROA 4FW4A 4LCGA 2IESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PS3 A;  3U1Y A;  4MDT A;  4IS9 A;  4U3D A;  4OKG A;  4FW7 A;  4LCH A;  5DRP A;  4FW6 A;  1XXE A;  3NZK A;  4U3B A;  2O3Z A;  1YH8 A;  2VES A;  3P3C A;  5DRQ A;  4FW5 A;  4LCF A;  3P3E A;  2GO4 A;  1YHC A;  3UHM A;  5DRR A;  3PS1 A;  2IER A;  2GO3 A;  3PS2 A;  2J65 A;  4J3D A;  1P42 A;  4OZE A;  2JT2 A;  3P3G A;  3P76 A;  4ISA A;  4FW3 A;  4MQY A;  5DRO A;  4FW4 A;  4LCG A;  2IES A; 
#chains in the Genus database with same CATH topology
 1NHJ A;  3KRN A;  5LMU E;  3PRY A;  4IS9 A;  3ZKD A;  1XNQ E;  4IFD D;  2V2Z A;  1XMQ I;  1UDQ A;  2PO1 A;  3PYE A;  2O1V A;  4B3S I;  1K47 A;  4DV3 I;  1HR0 I;  4DV1 I;  5LL6 R;  2R3V A;  1I94 E;  1VIS A;  4AID A;  4OO1 E;  2Z5B B;  1Z0V A;  1H73 A;  4JYA I;  1ELO A;  2GQ0 A;  4OZE A;  3T1H E;  2F1D A;  2UUA E;  5LMU I;  4OO1 D;  4FWG A;  1XNQ I;  4DR2 I;  3B78 A;  4X66 E;  2NN6 C;  2AJ4 A;  4USK A;  4IZK A;  2NN6 A;  3CWV A;  1PKP A;  1FI4 A;  4FW6 A;  3ZZT A;  1I94 I;  1E3H A;  4AIM A;  1HNZ E;  4EMD A;  2R42 A;  3QT6 A;  3J81 Q;  4N3O A;  2Z5C B;  3T1H I;  4BA2 B;  2UUA I;  4LOM A;  1OYP A;  2C39 A;  2JE6 A;  2UU9 E;  4LFC E;  5DRO A;  2NN6 E;  4X66 I;  1KTV A;  4OO1 B;  2HFU A;  4DR7 E;  1Z0W A;  1Z0T A;  3B8H A;  4LF4 E;  2JEA A;  2NN6 D;  1S4E A;  2A2D A;  1HNZ I;  4ZVI A;  4DR4 I;  1Z0C A;  3PYD A;  1Z5A A;  5C0X F;  2UU9 I;  1B62 A;  2J65 A;  4LFC I;  1MX0 A;  1OYS A;  2PNM A;  3ZZ0 A;  2EFG A;  2E1R A;  4DR7 I;  2F4V E;  1ZM3 A;  4LF4 I;  4JI6 E;  4MDT A;  5GME A;  2V34 A;  4UTG A;  3CDJ A;  5FLX Q;  1D6T A;  4IZK B;  4DR6 E;  4DV5 E;  1Y5Y A;  2Z5B A;  4MYU A;  5GMD A;  3K17 A;  2PNL A;  4IFD F;  2F4V I;  2VF3 A;  1H74 A;  4B3R E;  3QT8 A;  4JI6 I;  1Z0E A;  4JI1 E;  3V2U C;  1ZM2 A;  4OX9 I;  5IWA E;  4DR6 I;  4XTJ A;  4DV5 I;  4FW9 A;  3WU3 A;  2VES A;  2JEA B;  1Y4U A;  2Z5C A;  4LCF A;  1Y60 A;  3GON A;  4J3D A;  4MU3 A;  3F0N A;  1NHI A;  4DR5 E;  4B3R I;  3J80 C;  5JEA C;  2WNR B;  4DPU A;  3QT7 A;  1XNR E;  4JI1 I;  4DR1 E;  4LFB I;  5IWA I;  4JI4 E;  1USU A;  4BA1 B;  1U2R A;  3WU6 A;  4LF7 E;  3GME A;  1ZM9 A;  2IOQ A;  4Z7C A;  3LTO A;  3WU4 A;  4B3T I;  2BA1 G;  2V8P A;  1B63 A;  4FWD A;  2VQF E;  4DR2 E;  2CGE A;  3M6A A;  3QT5 A;  3NZK A;  1BKN A;  5FWK A;  3HKM A;  1YHC A;  4URL A;  4DR5 I;  5DRR A;  1Y6Z A;  3B4T A;  3WU5 A;  4DV4 E;  2CVE A;  4IZJ B;  1XNR I;  1EA6 A;  4DR1 I;  3B82 A;  4JI4 I;  1UDS A;  2V2Q A;  4DV0 E;  4LF7 I;  1Z5C A;  2IES A;  3ZZU A;  1MU5 A;  5C0X B;  4UT4 A;  3GLL A;  2VQF I;  2J7K A;  4GKJ E;  3Q6N A;  4LCH A;  4B3M E;  1XXE A;  4LF5 E;  4KHP E;  2BR2 B;  5DRQ A;  4AQY E;  3U1K A;  2Z5E A;  4DR4 E;  4DV4 I;  1EI1 A;  4LPF A;  3JAM C;  2BV3 A;  1N34 I;  1P42 A;  4DV0 I;  2PO2 B;  3Q1Q A;  4PRV A;  4DV2 I;  4DV7 E;  4MYT A;  4GKJ I;  1H7U A;  4DUY E;  4NXN E;  4JV5 E;  3GCM A;  1UEK A;  5JEA B;  4B3M I;  2ZM6 E;  1NHH A;  5K36 F;  4LF5 I;  4KHP I;  4AQY I;  1KVK A;  3M85 G;  1HK7 A;  3CDI A;  2HK2 A;  3PS1 A;  2DEI A;  4HYM A;  2WNR A;  4DV7 I;  3M85 D;  2X7I A;  4USM A;  1Z5B A;  1FWL A;  2JT2 A;  4NXN I;  3P76 A;  4MQY A;  4DUY I;  4JV5 I;  4BA1 A;  3LNU A;  2UXC E;  2ZM6 I;  4K0K E;  4MU1 A;  4WUC A;  4OKG A;  3L7Z B;  4LF8 E;  2CG9 A;  2HFS A;  4OX9 E;  5L3J A;  2BM1 A;  2LJP A;  3H1C A;  5EKW A;  4QNJ A;  4IZJ A;  4YY3 E;  3LPS A;  4X64 E;  4DPT A;  2UXD E;  5C0X C;  2UXC I;  2VQE E;  1S16 A;  3ZM7 A;  4RPF A;  5C0X A;  4FW4 A;  4YHH E;  4JI3 E;  4K0K I;  3K1J A;  2IOP A;  3T1Y E;  4DR3 E;  4LF8 I;  3PYF A;  1FNM A;  4U3D A;  2C38 B;  4LFB E;  5A2Q C;  2BR2 A;  5EL9 A;  3P3C A;  4B3T E;  1Y4S A;  3J80 Q;  1HNW E;  4YY3 I;  1HNX E;  3HUL A;  4X64 I;  5C0X E;  2UXD I;  2PO2 A;  4OO1 F;  2VQE I;  4IZJ D;  1Z59 A;  4QNK A;  4YHH I;  4JI3 I;  1PIE A;  2OI2 A;  3P3G A;  4PRX A;  4FW3 A;  1N32 E;  5C0X D;  3DD6 A;  5JEA A;  4DR3 I;  3T1Y I;  3V5R A;  4P52 A;  4IFD C;  2HKE A;  2XEX A;  4JI0 E;  1UDO A;  1MG7 A;  4FW7 A;  1HNW I;  1OJ4 A;  1HNX I;  4JI8 E;  4WUD A;  2ZIT A;  3P3E A;  4KQV A;  5LMN E;  3UHM A;  5K36 B;  2IER A;  1Z0G A;  2BA1 D;  5JEA E;  1N32 I;  5IT9 C;  4GQU A;  1DAR A;  4X62 E;  2NN6 F;  4JI0 I;  1N34 E;  3J7A M;  5JEA D;  2PNZ B;  4DV2 E;  1R6M A;  4R1F A;  3L7Z A;  4JI8 I;  4DXL A;  4U3B A;  2O3Z A;  3JAM Q;  5LMN I;  1H72 C;  1FJG E;  1USV A;  4DPY A;  1QZR A;  1N36 E;  1KKH A;  1NZ0 A;  4X62 I;  1ZXN A;  4HAC B;  2JEB B;  1J5E E;  4JI2 E;  4LCG A;  2C37 B;  4DUZ E;  4ED4 A;  1IBM E;  1Z0B A;  2C38 A;  2V2V A;  2PO0 B;  4GKK E;  2AE8 A;  2WW4 A;  4DPX A;  4IFD B;  1YH8 A;  1FJG I;  4WUB A;  5DNX A;  1N36 I;  1RR9 A;  4DU8 A;  2GO4 A;  4JG4 A;  2UXB E;  1KIJ A;  1XHK A;  2GO3 A;  3PYG A;  2WP8 B;  3Q6M A;  1J5E I;  4LF9 E;  1PVG A;  4JI2 I;  4DUZ I;  1IBM I;  2UUB E;  2BM0 A;  4JI7 E;  3J81 C;  4GKK I;  2Q2E B;  4PU9 A;  4LF6 E;  3H4L A;  2E5L E;  5DRP A;  1FWK A;  3ZKB A;  2NPF A;  2UXB I;  5K36 C;  1UDN A;  2PO1 B;  3M7N G;  5K36 A;  2DEJ A;  4LF9 I;  4HY1 A;  1RRE A;  4DV6 E;  1IBL E;  2ZBK B;  3D4J A;  2UUB I;  1ZM4 A;  4JI7 I;  2HHH E;  4AM3 A;  4DU7 A;  4JI5 E;  2CZ9 A;  5BR8 E;  4LFA E;  3M7N D;  1N0V C;  2PNZ A;  1XMO E;  5A2Q Q;  4NXM E;  2HKJ A;  4FWH A;  1H7S A;  4LF6 I;  2E5L I;  1E3P A;  3HJC A;  1IBK E;  5K36 E;  4X65 E;  2X36 A;  4I3H A;  2NN6 B;  4DV6 I;  4FW5 A;  1IBL I;  5K36 D;  5FLX C;  2HHH I;  1N33 E;  2GS8 A;  4DPW A;  5JEA F;  1FKA E;  3PS2 A;  4JI5 I;  4HAC A;  5BR8 I;  3OTO E;  4LFA I;  2JEB A;  1XMO I;  4MU4 A;  4NXM I;  2C37 A;  5DNL A;  2O1T A;  2C39 B;  2JE6 B;  2PO0 A;  1RHY A;  1IBK I;  1WUU A;  4X65 I;  3PS3 A;  2O1W A;  3U1Y A;  4FN5 A;  3P06 A;  1N0U A;  4IFD A;  2UUC E;  2O1U A;  4Z7Y A;  4NBQ A;  4HXZ A;  1A6F A;  2HK3 A;  1XMQ E;  1N33 I;  4P7A A;  5IT9 Q;  1R6L A;  4BA2 A;  1OYR A;  4B3S E;  2WP8 A;  4MU0 A;  3OTO I;  4DV3 E;  2BA0 G;  3K85 A;  1HR0 E;  4DV1 E;  3J7A G;  1VI7 A;  4OO1 C;  5ELW A;  1ZXM A;  4ISA A;  4IFD E;  4JYA E;  2A2C A;  4OO1 A;  2UUC I;  4M1K A;  2BA0 D; 
#chains in the Genus database with same CATH homology
 3PS3 A;  3U1Y A;  4MDT A;  4IS9 A;  4U3D A;  4OKG A;  4FW7 A;  4LCH A;  5DRP A;  4FW6 A;  1XXE A;  3NZK A;  4U3B A;  2O3Z A;  1YH8 A;  2VES A;  3P3C A;  5DRQ A;  4FW5 A;  4LCF A;  3P3E A;  2GO4 A;  1YHC A;  3UHM A;  5DRR A;  3PS1 A;  2IER A;  2GO3 A;  3PS2 A;  2J65 A;  4J3D A;  1P42 A;  4OZE A;  2JT2 A;  3P3G A;  3P76 A;  4ISA A;  4FW3 A;  4MQY A;  5DRO A;  4FW4 A;  4LCG A;  2IES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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