4FW7A

Crystal structure of the lpxc in complex with n-[(2s,3r)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]biphenyl-4-carboxamide inhibitor
Total Genus 93
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
93
sequence length
301
structure length
301
Chain Sequence
NAMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Crystal Structure of the LpxC
rcsb
source organism Pseudomonas aeruginosa
total genus 93
structure length 301
sequence length 301
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2012-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4fw7A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4fw7A02
4OKGA 4LCGA 5DRRA 2GO4A 2O3ZA 3P3EA 5DROA 5DRPA 4FW6A 4U3BA 5DRQA 2JT2A 2IESA 4FW3A 4MQYA 3NZKA 2VESA 4LCFA 3P3CA 1P42A 2GO3A 1YH8A 2J65A 3U1YA 3PS3A 4LCHA 4IS9A 4ISAA 3P3GA 2IERA 3PS2A 1YHCA 4U3DA 4FW4A 1XXEA 3PS1A 3UHMA 4MDTA 3P76A 4J3DA 4FW7A 4FW5A 4OZEA
chains in the Genus database with same CATH superfamily
4P52A 2HFSA 1D6TA 4DR5I 2HHHE 3GMEA 4Z7YA 2UU9I 4LF6I 4JV5I 2WP8B 2UUBE 4JI6E 5LMNI 1Z0GA 4DV2E 4B3RE 1WUUA 1NZ0A 4DR7E 5K36D 1HNZI 4KQVA 4LF5I 4HY1A 3ZZTA 2C39A 4NBQA 5JEAB 3ZZUA 4FW7A 4IZJD 4USKA 2HHHI 4DV3E 4RPFA 1Z5CA 3L7ZB 2DEIA 4JI6I 1N32I 1Z5BA 4FW6A 2Z5BB 4JYAE 2UXCE 2BR2B 4DV2I 4MU3A 2NN6E 2VF3A 5A2QC 4B3RI 4LF9I 4LCFA 1Y4SA 4DPYA 1FI4A 1Y4UA 4LF8E 4DV3I 1EI1A 1J5EE 3QT6A 3F0NA 4MDTA 1KKHA 2CVEA 2UUCE 4JI0E 4JYAI 1OYSA 2UXCI 4JI7E 4X64E 2O1UA 2PO1B 3J80Q 1RR9A 4AIDA 2NN6D 3QT8A 4K0KE 4HACA 2HKJA 2VESA 4GQUA 1RHYA 4B3ME 5IWAE 4PRVA 2LJPA 4OO1A 3U1YA 4LCHA 2IERA 4X66E 5FLXC 3B8HA 4FW9A 4JI0I 2C38A 4JG4A 4X64I 4MU4A 4DV6E 2BM0A 4MU0A 4K0KI 3HULA 1MU5A 2GS8A 2J7KA 2JEAA 4B3MI 5IWAI 1HNWE 5JEAD 4X62I 3ZZ0A 4IZJB 4LOMA 4X66I 1N0VC 2HKEA 3PS3A 2NPFA 4AQYE 3DD6A 4DR6I 5EL9A 3P3GA 1FNMA 2BA1G 4DV6I 1Z0BA 1IBLE 4JI1E 3WU5A 4IFDA 4M1KA 3PYFA 4HACB 1MX0A 2GO4A 1UDOA 2EFGA 5C0XA 4OO1B 2HK3A 4NXNI 1IBKE 4AQYI 2V8PA 2O1WA 3P3CA 2C38B 2PNZB 1P42A 2E1RA 2CGEA 1Y5YA 4JI5E 1IBLI 4OX9E 4JI1I 4EMDA 3PYGA 2Z5EA 3GCMA 1YHCA 5LMNE 4FN5A 1USUA 3KRNA 3PYDA 4LPFA 1BKNA 2JEAB 4YHHE 2VQFE 1B63A 4DUYE 2CZ9A 4JI2E 1R6MA 2UXDE 1Z0CA 2V2QA 3CWVA 1IBKI 5GMDA 5K36F 4JI5I 4LF7E 4OX9I 1N32E 1N0UA 2PO0A 5A2QQ 3LNUA 3CDIA 4YHHI 4IFDB 2VQFI 4LF9E 3H1CA 4DUYI 4JI2I 4N3OA 2UXDI 4DPWA 4DPTA 4X65E 2X36A 5C0XB 2R3VA 1PKPA 3ZKDA 4DV4E 2PO2B 4LF7I 4JI4E 1XMOI 4BA2A 4Z7CA 3GONA 3B4TA 3P06A 2DEJA 2IOPA 1Z5AA 5LMUE 1KIJA 4AIMA 2O1TA 5K36C 3M85D 4X65I 3PS2A 1H72C 1XMQE 4QNKA 4OO1D 4DV4I 1R6LA 2VQEE 4DR3E 5FLXQ 2NN6F 3ZKBA 4JI4I 1Y6ZA 4I3HA 4WUBA 5EKWA 3M85G 1Y60A 2OI2A 4DU7A 5L3JA 3PYEA 2HFUA 4NXME 5LMUI 2IESA 4FW3A 5GMEA 1USVA 5JEAE 4P7AA 1XMQI 2C39B 4QNJA 4DR1E 4AM3A 4X62E 2VQEI 1UEKA 3J7AM 4DR3I 3J81C 1XXEA 4GKKI 2WNRA 2AJ4A 4DPUA 4KHPE 4DR6E 1B62A 4BA2B 4NXMI 4OZEA 3K85A 5JEAF 3OTOE 5DRRA 1ZM2A 3WU6A 1QZRA 2JE6A 3H4LA 2C37A 1VI7A 2NN6C 4DUZE 4LFBE 4R1FA 4IFDD 2BA1D 2O1VA 4DR1I 3T1YE 4HYMA 5C0XD 4FWGA 4MYTA 2J65A 1UDQA 2JEBA 4NXNE 4KHPI 2XEXA 3OTOI 3LTOA 2V34A 1Z0VA 4XTJA 1H7SA 4DUZI 4LFBI 1NHIA 2NN6A 4JI8E 3T1HI 3T1YI 3HJCA 2A2CA 5JEAC 1FJGE 1PVGA 5FWKA 1ZXNA 3PRYA 1ZM9A 4WUCA 2ZM6I 2WP8A 2BM1A 1N36E 4JI8I 2JE6B 3HKMA 3P76A 2C37B 4J3DA 1I94I 3J7AG 3V2UC 1FJGI 5DRPA 1ZM4A 4DV0I 2JEBB 2JT2A 3L7ZA 1HK7A 4MQYA 3NZKA 2ZBKB 4B3SI 2Q2EB 1XMOE 2BR2A 2GQ0A 3M6AA 1N36I 1OJ4A 1H73A 3B78A 1K47A 3Q1QA 4U3DA 4B3TE 4LF4E 4OO1E 1Z0WA 4IZKA 4MU1A 1MG7A 3GLLA 1EA6A 4GKJE 4LCGA 4BA1A 2HK2A 5DROA 4DV5I 1N34E 4FWHA 1XNRE 2F1DA 4DU8A 4PU9A 4ED4A 2PO1A 4OO1F 2UUAE 4UTGA 3JAMQ 4B3TI 2A2DA 2Z5CA 4LF4I 1VISA 3V5RA 3LPSA 2X7IA 4GKJI 5BR8E 1UDSA 2BV3A 1E3HA 1A6FA 4YY3E 1N34I 3J81Q 3WU3A 1XNRI 4GKKE 1KTVA 2PNLA 1ZXMA 2UUBI 1NHHA 2UXBE 1DARA 1XHKA 2UUAI 4JI3E 3JAMC 1HNXE 4USMA 4DR7I 4IFDE 2PO0B 5K36A 1ZM3A 1PIEA 1OYPA 5C0XE 5BR8I 3Q6MA 4IZKB 1FKAE 2V2ZA 4IZJA 4OO1C 3K1JA 4YY3I 4FW4A 5ELWA 3CDJA 4BA1B 4IFDF 3WU4A 2UXBI 4DV1E 4JI3I 1ELOA 1S16A 1HNXI 5C0XF 2ZITA 1H74A 3P3EA 5DNLA 4HXZA 4U3BA 2Z5CB 1FWKA 4DR4E 3T1HE 4LF8I 3Q6NA 1KVKA 4LFAE 4DR2E 1J5EI 4ZVIA 1Z0EA 1YH8A 4ISAA 2UUCI 2PNZA 3M7ND 4DV1I 4JI7I 1H7UA 2ZM6E 4MYUA 1FWLA 3J80C 2CG9A 2AE8A 2V2VA 1RREA 5K36B 4DR4I 4IFDC 3M7NG 1I94E 4LFAI 5DNXA 1Z0TA 5DRQA 4DR2I 5C0XC 3B82A 2E5LE 4LFCE 4DV0E 2WNRB 4URLA 4DV7E 2PNMA 4DXLA 1IBME 1HR0E 1UDNA 2F4VE 4B3SE 4DPXA 3UHMA 1N33E 2WW4A 2BA0D 5LL6R 1U2RA 1OYRA 4OKGA 1HNWI 1XNQE 4WUDA 3QT5A 5JEAA 3K17A 2O3ZA 5IT9Q 1S4EA 2R42A 2E5LI 1E3PA 3QT7A 4LFCI 4DR5E 2BA0G 2PO2A 4DV7I 1NHJA 2UU9E 1IBMI 4DV5E 2IOQA 4FWDA 1HR0I 3D4JA 2F4VI 2GO3A 2Z5BA 4UT4A 4LF6E 4JV5E 3ZM7A 1N33I 4IS9A 5K36E 4PRXA 3U1KA 2NN6B 3PS1A 1XNQI 1HNZE 4LF5E 4FW5A 1Z59A 5IT9C
chains in the Genus database with same CATH topology
4OKGA 4LCGA 5DRRA 2GO4A 2O3ZA 3P3EA 5DROA 5DRPA 4FW6A 4U3BA 5DRQA 2JT2A 2IESA 4FW3A 4MQYA 3NZKA 2VESA 4LCFA 3P3CA 1P42A 2GO3A 1YH8A 2J65A 3U1YA 3PS3A 4LCHA 4IS9A 4ISAA 3P3GA 2IERA 3PS2A 1YHCA 4U3DA 4FW4A 1XXEA 3PS1A 3UHMA 4MDTA 3P76A 4J3DA 4FW7A 4FW5A 4OZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OKG A;  4LCG A;  5DRR A;  2GO4 A;  2O3Z A;  3P3E A;  5DRO A;  5DRP A;  4FW6 A;  4U3B A;  5DRQ A;  2JT2 A;  2IES A;  4FW3 A;  4MQY A;  3NZK A;  2VES A;  4LCF A;  3P3C A;  1P42 A;  2GO3 A;  1YH8 A;  2J65 A;  3U1Y A;  3PS3 A;  4LCH A;  4IS9 A;  4ISA A;  3P3G A;  2IER A;  3PS2 A;  1YHC A;  4U3D A;  4FW4 A;  1XXE A;  3PS1 A;  3UHM A;  4MDT A;  3P76 A;  4J3D A;  4FW7 A;  4FW5 A;  4OZE A; 
#chains in the Genus database with same CATH topology
 4P52 A;  2HFS A;  1D6T A;  4DR5 I;  2HHH E;  3GME A;  4Z7Y A;  2UU9 I;  4LF6 I;  4JV5 I;  2WP8 B;  2UUB E;  4JI6 E;  5LMN I;  1Z0G A;  4DV2 E;  4B3R E;  1WUU A;  1NZ0 A;  4DR7 E;  5K36 D;  1HNZ I;  4KQV A;  4LF5 I;  4HY1 A;  3ZZT A;  2C39 A;  4NBQ A;  5JEA B;  3ZZU A;  4FW7 A;  4IZJ D;  4USK A;  2HHH I;  4DV3 E;  4RPF A;  1Z5C A;  3L7Z B;  2DEI A;  4JI6 I;  1N32 I;  1Z5B A;  4FW6 A;  2Z5B B;  4JYA E;  2UXC E;  2BR2 B;  4DV2 I;  4MU3 A;  2NN6 E;  2VF3 A;  5A2Q C;  4B3R I;  4LF9 I;  4LCF A;  1Y4S A;  4DPY A;  1FI4 A;  1Y4U A;  4LF8 E;  4DV3 I;  1EI1 A;  1J5E E;  3QT6 A;  3F0N A;  4MDT A;  1KKH A;  2CVE A;  2UUC E;  4JI0 E;  4JYA I;  1OYS A;  2UXC I;  4JI7 E;  4X64 E;  2O1U A;  2PO1 B;  3J80 Q;  1RR9 A;  4AID A;  2NN6 D;  3QT8 A;  4K0K E;  4HAC A;  2HKJ A;  2VES A;  4GQU A;  1RHY A;  4B3M E;  5IWA E;  4PRV A;  2LJP A;  4OO1 A;  3U1Y A;  4LCH A;  2IER A;  4X66 E;  5FLX C;  3B8H A;  4FW9 A;  4JI0 I;  2C38 A;  4JG4 A;  4X64 I;  4MU4 A;  4DV6 E;  2BM0 A;  4MU0 A;  4K0K I;  3HUL A;  1MU5 A;  2GS8 A;  2J7K A;  2JEA A;  4B3M I;  5IWA I;  1HNW E;  5JEA D;  4X62 I;  3ZZ0 A;  4IZJ B;  4LOM A;  4X66 I;  1N0V C;  2HKE A;  3PS3 A;  2NPF A;  4AQY E;  3DD6 A;  4DR6 I;  5EL9 A;  3P3G A;  1FNM A;  2BA1 G;  4DV6 I;  1Z0B A;  1IBL E;  4JI1 E;  3WU5 A;  4IFD A;  4M1K A;  3PYF A;  4HAC B;  1MX0 A;  2GO4 A;  1UDO A;  2EFG A;  5C0X A;  4OO1 B;  2HK3 A;  4NXN I;  1IBK E;  4AQY I;  2V8P A;  2O1W A;  3P3C A;  2C38 B;  2PNZ B;  1P42 A;  2E1R A;  2CGE A;  1Y5Y A;  4JI5 E;  1IBL I;  4OX9 E;  4JI1 I;  4EMD A;  3PYG A;  2Z5E A;  3GCM A;  1YHC A;  5LMN E;  4FN5 A;  1USU A;  3KRN A;  3PYD A;  4LPF A;  1BKN A;  2JEA B;  4YHH E;  2VQF E;  1B63 A;  4DUY E;  2CZ9 A;  4JI2 E;  1R6M A;  2UXD E;  1Z0C A;  2V2Q A;  3CWV A;  1IBK I;  5GMD A;  5K36 F;  4JI5 I;  4LF7 E;  4OX9 I;  1N32 E;  1N0U A;  2PO0 A;  5A2Q Q;  3LNU A;  3CDI A;  4YHH I;  4IFD B;  2VQF I;  4LF9 E;  3H1C A;  4DUY I;  4JI2 I;  4N3O A;  2UXD I;  4DPW A;  4DPT A;  4X65 E;  2X36 A;  5C0X B;  2R3V A;  1PKP A;  3ZKD A;  4DV4 E;  2PO2 B;  4LF7 I;  4JI4 E;  1XMO I;  4BA2 A;  4Z7C A;  3GON A;  3B4T A;  3P06 A;  2DEJ A;  2IOP A;  1Z5A A;  5LMU E;  1KIJ A;  4AIM A;  2O1T A;  5K36 C;  3M85 D;  4X65 I;  3PS2 A;  1H72 C;  1XMQ E;  4QNK A;  4OO1 D;  4DV4 I;  1R6L A;  2VQE E;  4DR3 E;  5FLX Q;  2NN6 F;  3ZKB A;  4JI4 I;  1Y6Z A;  4I3H A;  4WUB A;  5EKW A;  3M85 G;  1Y60 A;  2OI2 A;  4DU7 A;  5L3J A;  3PYE A;  2HFU A;  4NXM E;  5LMU I;  2IES A;  4FW3 A;  5GME A;  1USV A;  5JEA E;  4P7A A;  1XMQ I;  2C39 B;  4QNJ A;  4DR1 E;  4AM3 A;  4X62 E;  2VQE I;  1UEK A;  3J7A M;  4DR3 I;  3J81 C;  1XXE A;  4GKK I;  2WNR A;  2AJ4 A;  4DPU A;  4KHP E;  4DR6 E;  1B62 A;  4BA2 B;  4NXM I;  4OZE A;  3K85 A;  5JEA F;  3OTO E;  5DRR A;  1ZM2 A;  3WU6 A;  1QZR A;  2JE6 A;  3H4L A;  2C37 A;  1VI7 A;  2NN6 C;  4DUZ E;  4LFB E;  4R1F A;  4IFD D;  2BA1 D;  2O1V A;  4DR1 I;  3T1Y E;  4HYM A;  5C0X D;  4FWG A;  4MYT A;  2J65 A;  1UDQ A;  2JEB A;  4NXN E;  4KHP I;  2XEX A;  3OTO I;  3LTO A;  2V34 A;  1Z0V A;  4XTJ A;  1H7S A;  4DUZ I;  4LFB I;  1NHI A;  2NN6 A;  4JI8 E;  3T1H I;  3T1Y I;  3HJC A;  2A2C A;  5JEA C;  1FJG E;  1PVG A;  5FWK A;  1ZXN A;  3PRY A;  1ZM9 A;  4WUC A;  2ZM6 I;  2WP8 A;  2BM1 A;  1N36 E;  4JI8 I;  2JE6 B;  3HKM A;  3P76 A;  2C37 B;  4J3D A;  1I94 I;  3J7A G;  3V2U C;  1FJG I;  5DRP A;  1ZM4 A;  4DV0 I;  2JEB B;  2JT2 A;  3L7Z A;  1HK7 A;  4MQY A;  3NZK A;  2ZBK B;  4B3S I;  2Q2E B;  1XMO E;  2BR2 A;  2GQ0 A;  3M6A A;  1N36 I;  1OJ4 A;  1H73 A;  3B78 A;  1K47 A;  3Q1Q A;  4U3D A;  4B3T E;  4LF4 E;  4OO1 E;  1Z0W A;  4IZK A;  4MU1 A;  1MG7 A;  3GLL A;  1EA6 A;  4GKJ E;  4LCG A;  4BA1 A;  2HK2 A;  5DRO A;  4DV5 I;  1N34 E;  4FWH A;  1XNR E;  2F1D A;  4DU8 A;  4PU9 A;  4ED4 A;  2PO1 A;  4OO1 F;  2UUA E;  4UTG A;  3JAM Q;  4B3T I;  2A2D A;  2Z5C A;  4LF4 I;  1VIS A;  3V5R A;  3LPS A;  2X7I A;  4GKJ I;  5BR8 E;  1UDS A;  2BV3 A;  1E3H A;  1A6F A;  4YY3 E;  1N34 I;  3J81 Q;  3WU3 A;  1XNR I;  4GKK E;  1KTV A;  2PNL A;  1ZXM A;  2UUB I;  1NHH A;  2UXB E;  1DAR A;  1XHK A;  2UUA I;  4JI3 E;  3JAM C;  1HNX E;  4USM A;  4DR7 I;  4IFD E;  2PO0 B;  5K36 A;  1ZM3 A;  1PIE A;  1OYP A;  5C0X E;  5BR8 I;  3Q6M A;  4IZK B;  1FKA E;  2V2Z A;  4IZJ A;  4OO1 C;  3K1J A;  4YY3 I;  4FW4 A;  5ELW A;  3CDJ A;  4BA1 B;  4IFD F;  3WU4 A;  2UXB I;  4DV1 E;  4JI3 I;  1ELO A;  1S16 A;  1HNX I;  5C0X F;  2ZIT A;  1H74 A;  3P3E A;  5DNL A;  4HXZ A;  4U3B A;  2Z5C B;  1FWK A;  4DR4 E;  3T1H E;  4LF8 I;  3Q6N A;  1KVK A;  4LFA E;  4DR2 E;  1J5E I;  4ZVI A;  1Z0E A;  1YH8 A;  4ISA A;  2UUC I;  2PNZ A;  3M7N D;  4DV1 I;  4JI7 I;  1H7U A;  2ZM6 E;  4MYU A;  1FWL A;  3J80 C;  2CG9 A;  2AE8 A;  2V2V A;  1RRE A;  5K36 B;  4DR4 I;  4IFD C;  3M7N G;  1I94 E;  4LFA I;  5DNX A;  1Z0T A;  5DRQ A;  4DR2 I;  5C0X C;  3B82 A;  2E5L E;  4LFC E;  4DV0 E;  2WNR B;  4URL A;  4DV7 E;  2PNM A;  4DXL A;  1IBM E;  1HR0 E;  1UDN A;  2F4V E;  4B3S E;  4DPX A;  3UHM A;  1N33 E;  2WW4 A;  2BA0 D;  5LL6 R;  1U2R A;  1OYR A;  4OKG A;  1HNW I;  1XNQ E;  4WUD A;  3QT5 A;  5JEA A;  3K17 A;  2O3Z A;  5IT9 Q;  1S4E A;  2R42 A;  2E5L I;  1E3P A;  3QT7 A;  4LFC I;  4DR5 E;  2BA0 G;  2PO2 A;  4DV7 I;  1NHJ A;  2UU9 E;  1IBM I;  4DV5 E;  2IOQ A;  4FWD A;  1HR0 I;  3D4J A;  2F4V I;  2GO3 A;  2Z5B A;  4UT4 A;  4LF6 E;  4JV5 E;  3ZM7 A;  1N33 I;  4IS9 A;  5K36 E;  4PRX A;  3U1K A;  2NN6 B;  3PS1 A;  1XNQ I;  1HNZ E;  4LF5 E;  4FW5 A;  1Z59 A;  5IT9 C; 
#chains in the Genus database with same CATH homology
 4OKG A;  4LCG A;  5DRR A;  2GO4 A;  2O3Z A;  3P3E A;  5DRO A;  5DRP A;  4FW6 A;  4U3B A;  5DRQ A;  2JT2 A;  2IES A;  4FW3 A;  4MQY A;  3NZK A;  2VES A;  4LCF A;  3P3C A;  1P42 A;  2GO3 A;  1YH8 A;  2J65 A;  3U1Y A;  3PS3 A;  4LCH A;  4IS9 A;  4ISA A;  3P3G A;  2IER A;  3PS2 A;  1YHC A;  4U3D A;  4FW4 A;  1XXE A;  3PS1 A;  3UHM A;  4MDT A;  3P76 A;  4J3D A;  4FW7 A;  4FW5 A;  4OZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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