4FW6A

Crystal structure of the lpxc in complex with n-[(2s,3r)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]-4-(phenylethynyl)benzamide inhibitor
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
300
structure length
300
Chain Sequence
AMIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structure of the LpxC
rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Pseudomonas aeruginosa
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 88
structure length 300
sequence length 300
chains with identical sequence B, C, D
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2012-06-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4fw6A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4fw6A02
4MDTA 1YH8A 3PS1A 4FW7A 4MQYA 3UHMA 1YHCA 4J3DA 2IESA 4FW3A 2JT2A 3PS2A 4FW4A 2GO4A 5DRRA 1XXEA 5DROA 4ISAA 3U1YA 3P3GA 3P3EA 4FW6A 5DRQA 4U3BA 5DRPA 3PS3A 4OZEA 4LCFA 4U3DA 2O3ZA 4IS9A 2GO3A 3P3CA 4OKGA 4LCGA 3P76A 4FW5A 3NZKA 1P42A 2J65A 2IERA 2VESA 4LCHA
chains in the Genus database with same CATH superfamily
4P52A 2UUAI 4LF4I 1HNWE 1OJ4A 1YHCA 3LPSA 4NBQA 4GQUA 4WUCA 4DV3I 1N32I 4DU7A 1FNMA 4DUYE 3P3GA 2C39B 1OYPA 3PS3A 1Y4UA 1EI1A 1I94E 4GKJE 4DV6E 1Y60A 4LCGA 3V5RA 3B8HA 3GONA 4B3RE 4OO1D 4LPFA 5C0XC 4MU3A 2NN6C 3QT7A 4JI8I 3Q6MA 1H7UA 4OO1E 4PRVA 4JI4E 1PKPA 4DV2I 3CWVA 2PO2B 3LTOA 4FW4A 5JEAF 4IZJB 4LF9I 1S16A 1RHYA 3WU3A 1BKNA 4DV7E 4JI3I 4ED4A 4AM3A 4DV4E 2V2QA 4LFBI 4DV0E 2C38B 1UDQA 4OX9E 1IBMI 2ZM6I 1IBLE 1UDNA 3KRNA 4I3HA 1A6FA 1N0VC 4J3DA 2V8PA 4LF8E 4UT4A 4DV5I 1XMQE 4JI0I 1RR9A 5EL9A 1XXEA 1ZM2A 4LFAE 5DRQA 1HNXI 3QT5A 2F1DA 4DR4E 1D6TA 5GMEA 2O1TA 1MG7A 2GO3A 1Z59A 2UXCI 4IFDF 5K36C 4X64I 3M85D 5DNLA 2JEBA 2VQFE 4WUBA 1P42A 4YHHE 2IOQA 4Z7YA 1NHIA 3OTOI 2PO0A 3K17A 4DPWA 3UHMA 1N34I 3J80Q 2JT2A 1QZRA 4AQYE 4LF5E 1ELOA 1ZM4A 3GMEA 4DPXA 5DROA 5IWAI 2C39A 4JI7E 4X65I 2VQEE 3LNUA 5BR8E 4BA1B 4FW9A 2HFUA 4N3OA 3Q6NA 4OO1F 1XNRI 3J81Q 5IT9Q 2WNRB 4JI2E 5K36A 2BR2B 2IESA 4FW3A 5C0XB 4DV1I 2NN6B 2PO2A 4DR5I 4NXNI 4IZJA 1R6MA 3J7AG 1VI7A 2F4VI 2Q2EB 3B78A 1N36I 1ZXNA 4FN5A 1Y6ZA 1Z0GA 4BA2B 4IS9A 3F0NA 5GMDA 1FI4A 2R42A 4B3TI 2O1WA 4LFCI 1K47A 2HHHI 1KIJA 1IBKI 4DR7E 2O1UA 2HK3A 2X36A 1UEKA 3GLLA 1NHJA 4X66I 1ZM3A 1FWKA 4LF6I 3PYEA 1NHHA 2GO4A 3JAMQ 3U1YA 5LMUI 4FW6A 1H73A 4WUDA 1NZ0A 5LL6R 5ELWA 1KTVA 4AIMA 2E5LE 1B62A 4DR6E 1HR0I 4DV5E 2CGEA 5C0XD 4LF7I 2NN6D 2UUBE 4FW7A 4DUZE 5K36B 2DEIA 5C0XE 2UUCE 4DR1E 2NN6E 2UXCE 2Z5BB 2UU9E 4JI1I 5DRPA 1FJGE 2CVEA 1XMOE 4JV5I 3OTOE 5EKWA 4KHPI 4JI5I 1Z5CA 3CDIA 4BA1A 4Z7CA 4NXMI 3WU6A 1N33E 1H7SA 2A2CA 1Y4SA 1J5EI 3PS1A 1USUA 2WNRA 3T1HI 4GKKI 4QNJA 2BR2A 4MYUA 5C0XA 1B63A 2HKEA 2NN6A 5JEAB 4K0KE 1HNWI 4USKA 4ISAA 4MU1A 3T1YE 1XNQE 4B3ME 4B3SI 4BA2A 4DUYI 1XNRE 4OKGA 1HK7A 2O1VA 2EFGA 1I94I 4GKJI 4DXLA 2J65A 4B3RI 2VF3A 2LJPA 3B82A 4FWGA 2VESA 4LCHA 1N0UA 4DR5E 2UXBI 5K36D 4MDTA 4IZJD 4XTJA 4DR3I 2R3VA 3PYGA 5LMNE 1N36E 5K36E 2DEJA 1U2RA 2IOPA 4MYTA 2OI2A 2BA1D 1FKAE 3H1CA 1HNZE 4U3DA 4YY3E 4DV7I 5L3JA 4IFDB 5A2QQ 1R6LA 2UUAE 4LF4E 4DV4I 5JEAC 3J80C 2JEAB 4DV0I 2HFSA 4DV3E 1WUUA 1E3HA 2X7IA 4OX9I 2BM0A 1N32E 1Z5AA 1RREA 2PNLA 4MQYA 5C0XF 2NN6F 2V34A 1IBLI 2ZBKB 5JEAE 2Z5BA 3ZZUA 4LF8I 3J7AM 5FLXQ 4LCFA 3P3CA 4AIDA 4JI8E 4LFAI 4PU9A 1Z0EA 4LOMA 3J81C 5IT9C 4DR4I 1OYRA 2BA1G 2UXDI 4DV2E 2IERA 2C37A 1OYSA 4LF9E 2VQFI 4USMA 2Z5CB 4YHHI 4JI3E 1Z0TA 5JEAA 4IFDC 5FWKA 5DRRA 1H74A 1DARA 1Z0WA 4LFBE 2NPFA 2GS8A 3GCMA 3ZKBA 2V2ZA 3HULA 1IBME 4LF5I 2PNZA 2ZM6E 4JYAI 3T1HE 4IFDE 4JI7I 4GKKE 4JG4A 4DPTA 5BR8I 4JI6I 3M7ND 1YH8A 3JAMC 4JI0E 5K36F 1HNXE 4B3SE 4DR2I 4JI2I 2CG9A 2PNMA 3HKMA 1Y5YA 4HXZA 1E3PA 4X64E 4OO1C 4HY1A 2O3ZA 4HACB 4DU8A 4QNKA 2UXBE 4URLA 4X62I 4IFDA 3B4TA 4DR3E 4KQVA 3WU5A 1UDSA 2WP8B 3ZZ0A 1N34E 2JEAA 2C37B 4DPUA 4DR7I 3M6AA 5IWAE 1FWLA 2PO1B 1H72C 1MX0A 4X65E 2BA0D 4FWHA 4DPYA 3M7NG 4FWDA 3QT8A 4ZVIA 4IZKB 3Q1QA 2CZ9A 2PNZB 2JE6B 4EMDA 2HK2A 2AJ4A 4FW5A 1Z0BA 1Z5BA 1VISA 4OO1A 4DV6I 4DV1E 3H4LA 3P06A 4NXNE 4R1FA 2E5LI 4UTGA 4DR6I 2Z5CA 2F4VE 1PIEA 2BV3A 2UUBI 3L7ZA 2A2DA 4DUZI 4JI4I 4P7AA 4B3TE 4LFCE 3CDJA 2Z5EA 2UUCI 4DR1I 1KVKA 2UXDE 2HHHE 1IBKE 2AE8A 2UU9I 3P76A 2BA0G 4MU0A 1FJGI 4X66E 3WU4A 2HKJA 3DD6A 1XMOI 3NZKA 3PYDA 1Z0CA 4LF6E 3D4JA 3PRYA 2BM1A 2E1RA 5JEAD 5DNXA 1XHKA 4HYMA 5LMUE 4M1KA 1N33I 3PS2A 3PYFA 3ZKDA 1USVA 2XEXA 4JYAE 1KKHA 2ZITA 5A2QC 4MU4A 4OZEA 4K0KI 1XMQI 3HJCA 4HACA 3T1YI 1HR0E 1XNQI 4JI6E 1UDOA 4LF7E 3K1JA 4B3MI 2WP8A 1MU5A 4DR2E 4OO1B 3U1KA 3ZM7A 1ZXMA 3M85G 1Z0VA 2V2VA 4JI1E 5FLXC 2PO1A 2WW4A 1S4EA 3L7ZB 5LMNI 1EA6A 4PRXA 2J7KA 4X62E 4JV5E 3P3EA 4KHPE 1PVGA 4U3BA 4JI5E 4AQYI 4IFDD 4IZKA 3K85A 4NXME 2C38A 1ZM9A 1HNZI 2JE6A 3QT6A 3V2UC 2JEBB 1J5EE 3ZZTA 4YY3I 4RPFA 2VQEI 2GQ0A 2PO0B
chains in the Genus database with same CATH topology
4MDTA 1YH8A 3PS1A 4FW7A 4MQYA 3UHMA 1YHCA 4J3DA 2IESA 4FW3A 2JT2A 3PS2A 4FW4A 2GO4A 5DRRA 1XXEA 5DROA 4ISAA 3U1YA 3P3GA 3P3EA 4FW6A 5DRQA 4U3BA 5DRPA 3PS3A 4OZEA 4LCFA 4U3DA 2O3ZA 4IS9A 2GO3A 3P3CA 4OKGA 4LCGA 3P76A 4FW5A 3NZKA 1P42A 2J65A 2IERA 2VESA 4LCHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MDT A;  1YH8 A;  3PS1 A;  4FW7 A;  4MQY A;  3UHM A;  1YHC A;  4J3D A;  2IES A;  4FW3 A;  2JT2 A;  3PS2 A;  4FW4 A;  2GO4 A;  5DRR A;  1XXE A;  5DRO A;  4ISA A;  3U1Y A;  3P3G A;  3P3E A;  4FW6 A;  5DRQ A;  4U3B A;  5DRP A;  3PS3 A;  4OZE A;  4LCF A;  4U3D A;  2O3Z A;  4IS9 A;  2GO3 A;  3P3C A;  4OKG A;  4LCG A;  3P76 A;  4FW5 A;  3NZK A;  1P42 A;  2J65 A;  2IER A;  2VES A;  4LCH A; 
#chains in the Genus database with same CATH topology
 4P52 A;  2UUA I;  4LF4 I;  1HNW E;  1OJ4 A;  1YHC A;  3LPS A;  4NBQ A;  4GQU A;  4WUC A;  4DV3 I;  1N32 I;  4DU7 A;  1FNM A;  4DUY E;  3P3G A;  2C39 B;  1OYP A;  3PS3 A;  1Y4U A;  1EI1 A;  1I94 E;  4GKJ E;  4DV6 E;  1Y60 A;  4LCG A;  3V5R A;  3B8H A;  3GON A;  4B3R E;  4OO1 D;  4LPF A;  5C0X C;  4MU3 A;  2NN6 C;  3QT7 A;  4JI8 I;  3Q6M A;  1H7U A;  4OO1 E;  4PRV A;  4JI4 E;  1PKP A;  4DV2 I;  3CWV A;  2PO2 B;  3LTO A;  4FW4 A;  5JEA F;  4IZJ B;  4LF9 I;  1S16 A;  1RHY A;  3WU3 A;  1BKN A;  4DV7 E;  4JI3 I;  4ED4 A;  4AM3 A;  4DV4 E;  2V2Q A;  4LFB I;  4DV0 E;  2C38 B;  1UDQ A;  4OX9 E;  1IBM I;  2ZM6 I;  1IBL E;  1UDN A;  3KRN A;  4I3H A;  1A6F A;  1N0V C;  4J3D A;  2V8P A;  4LF8 E;  4UT4 A;  4DV5 I;  1XMQ E;  4JI0 I;  1RR9 A;  5EL9 A;  1XXE A;  1ZM2 A;  4LFA E;  5DRQ A;  1HNX I;  3QT5 A;  2F1D A;  4DR4 E;  1D6T A;  5GME A;  2O1T A;  1MG7 A;  2GO3 A;  1Z59 A;  2UXC I;  4IFD F;  5K36 C;  4X64 I;  3M85 D;  5DNL A;  2JEB A;  2VQF E;  4WUB A;  1P42 A;  4YHH E;  2IOQ A;  4Z7Y A;  1NHI A;  3OTO I;  2PO0 A;  3K17 A;  4DPW A;  3UHM A;  1N34 I;  3J80 Q;  2JT2 A;  1QZR A;  4AQY E;  4LF5 E;  1ELO A;  1ZM4 A;  3GME A;  4DPX A;  5DRO A;  5IWA I;  2C39 A;  4JI7 E;  4X65 I;  2VQE E;  3LNU A;  5BR8 E;  4BA1 B;  4FW9 A;  2HFU A;  4N3O A;  3Q6N A;  4OO1 F;  1XNR I;  3J81 Q;  5IT9 Q;  2WNR B;  4JI2 E;  5K36 A;  2BR2 B;  2IES A;  4FW3 A;  5C0X B;  4DV1 I;  2NN6 B;  2PO2 A;  4DR5 I;  4NXN I;  4IZJ A;  1R6M A;  3J7A G;  1VI7 A;  2F4V I;  2Q2E B;  3B78 A;  1N36 I;  1ZXN A;  4FN5 A;  1Y6Z A;  1Z0G A;  4BA2 B;  4IS9 A;  3F0N A;  5GMD A;  1FI4 A;  2R42 A;  4B3T I;  2O1W A;  4LFC I;  1K47 A;  2HHH I;  1KIJ A;  1IBK I;  4DR7 E;  2O1U A;  2HK3 A;  2X36 A;  1UEK A;  3GLL A;  1NHJ A;  4X66 I;  1ZM3 A;  1FWK A;  4LF6 I;  3PYE A;  1NHH A;  2GO4 A;  3JAM Q;  3U1Y A;  5LMU I;  4FW6 A;  1H73 A;  4WUD A;  1NZ0 A;  5LL6 R;  5ELW A;  1KTV A;  4AIM A;  2E5L E;  1B62 A;  4DR6 E;  1HR0 I;  4DV5 E;  2CGE A;  5C0X D;  4LF7 I;  2NN6 D;  2UUB E;  4FW7 A;  4DUZ E;  5K36 B;  2DEI A;  5C0X E;  2UUC E;  4DR1 E;  2NN6 E;  2UXC E;  2Z5B B;  2UU9 E;  4JI1 I;  5DRP A;  1FJG E;  2CVE A;  1XMO E;  4JV5 I;  3OTO E;  5EKW A;  4KHP I;  4JI5 I;  1Z5C A;  3CDI A;  4BA1 A;  4Z7C A;  4NXM I;  3WU6 A;  1N33 E;  1H7S A;  2A2C A;  1Y4S A;  1J5E I;  3PS1 A;  1USU A;  2WNR A;  3T1H I;  4GKK I;  4QNJ A;  2BR2 A;  4MYU A;  5C0X A;  1B63 A;  2HKE A;  2NN6 A;  5JEA B;  4K0K E;  1HNW I;  4USK A;  4ISA A;  4MU1 A;  3T1Y E;  1XNQ E;  4B3M E;  4B3S I;  4BA2 A;  4DUY I;  1XNR E;  4OKG A;  1HK7 A;  2O1V A;  2EFG A;  1I94 I;  4GKJ I;  4DXL A;  2J65 A;  4B3R I;  2VF3 A;  2LJP A;  3B82 A;  4FWG A;  2VES A;  4LCH A;  1N0U A;  4DR5 E;  2UXB I;  5K36 D;  4MDT A;  4IZJ D;  4XTJ A;  4DR3 I;  2R3V A;  3PYG A;  5LMN E;  1N36 E;  5K36 E;  2DEJ A;  1U2R A;  2IOP A;  4MYT A;  2OI2 A;  2BA1 D;  1FKA E;  3H1C A;  1HNZ E;  4U3D A;  4YY3 E;  4DV7 I;  5L3J A;  4IFD B;  5A2Q Q;  1R6L A;  2UUA E;  4LF4 E;  4DV4 I;  5JEA C;  3J80 C;  2JEA B;  4DV0 I;  2HFS A;  4DV3 E;  1WUU A;  1E3H A;  2X7I A;  4OX9 I;  2BM0 A;  1N32 E;  1Z5A A;  1RRE A;  2PNL A;  4MQY A;  5C0X F;  2NN6 F;  2V34 A;  1IBL I;  2ZBK B;  5JEA E;  2Z5B A;  3ZZU A;  4LF8 I;  3J7A M;  5FLX Q;  4LCF A;  3P3C A;  4AID A;  4JI8 E;  4LFA I;  4PU9 A;  1Z0E A;  4LOM A;  3J81 C;  5IT9 C;  4DR4 I;  1OYR A;  2BA1 G;  2UXD I;  4DV2 E;  2IER A;  2C37 A;  1OYS A;  4LF9 E;  2VQF I;  4USM A;  2Z5C B;  4YHH I;  4JI3 E;  1Z0T A;  5JEA A;  4IFD C;  5FWK A;  5DRR A;  1H74 A;  1DAR A;  1Z0W A;  4LFB E;  2NPF A;  2GS8 A;  3GCM A;  3ZKB A;  2V2Z A;  3HUL A;  1IBM E;  4LF5 I;  2PNZ A;  2ZM6 E;  4JYA I;  3T1H E;  4IFD E;  4JI7 I;  4GKK E;  4JG4 A;  4DPT A;  5BR8 I;  4JI6 I;  3M7N D;  1YH8 A;  3JAM C;  4JI0 E;  5K36 F;  1HNX E;  4B3S E;  4DR2 I;  4JI2 I;  2CG9 A;  2PNM A;  3HKM A;  1Y5Y A;  4HXZ A;  1E3P A;  4X64 E;  4OO1 C;  4HY1 A;  2O3Z A;  4HAC B;  4DU8 A;  4QNK A;  2UXB E;  4URL A;  4X62 I;  4IFD A;  3B4T A;  4DR3 E;  4KQV A;  3WU5 A;  1UDS A;  2WP8 B;  3ZZ0 A;  1N34 E;  2JEA A;  2C37 B;  4DPU A;  4DR7 I;  3M6A A;  5IWA E;  1FWL A;  2PO1 B;  1H72 C;  1MX0 A;  4X65 E;  2BA0 D;  4FWH A;  4DPY A;  3M7N G;  4FWD A;  3QT8 A;  4ZVI A;  4IZK B;  3Q1Q A;  2CZ9 A;  2PNZ B;  2JE6 B;  4EMD A;  2HK2 A;  2AJ4 A;  4FW5 A;  1Z0B A;  1Z5B A;  1VIS A;  4OO1 A;  4DV6 I;  4DV1 E;  3H4L A;  3P06 A;  4NXN E;  4R1F A;  2E5L I;  4UTG A;  4DR6 I;  2Z5C A;  2F4V E;  1PIE A;  2BV3 A;  2UUB I;  3L7Z A;  2A2D A;  4DUZ I;  4JI4 I;  4P7A A;  4B3T E;  4LFC E;  3CDJ A;  2Z5E A;  2UUC I;  4DR1 I;  1KVK A;  2UXD E;  2HHH E;  1IBK E;  2AE8 A;  2UU9 I;  3P76 A;  2BA0 G;  4MU0 A;  1FJG I;  4X66 E;  3WU4 A;  2HKJ A;  3DD6 A;  1XMO I;  3NZK A;  3PYD A;  1Z0C A;  4LF6 E;  3D4J A;  3PRY A;  2BM1 A;  2E1R A;  5JEA D;  5DNX A;  1XHK A;  4HYM A;  5LMU E;  4M1K A;  1N33 I;  3PS2 A;  3PYF A;  3ZKD A;  1USV A;  2XEX A;  4JYA E;  1KKH A;  2ZIT A;  5A2Q C;  4MU4 A;  4OZE A;  4K0K I;  1XMQ I;  3HJC A;  4HAC A;  3T1Y I;  1HR0 E;  1XNQ I;  4JI6 E;  1UDO A;  4LF7 E;  3K1J A;  4B3M I;  2WP8 A;  1MU5 A;  4DR2 E;  4OO1 B;  3U1K A;  3ZM7 A;  1ZXM A;  3M85 G;  1Z0V A;  2V2V A;  4JI1 E;  5FLX C;  2PO1 A;  2WW4 A;  1S4E A;  3L7Z B;  5LMN I;  1EA6 A;  4PRX A;  2J7K A;  4X62 E;  4JV5 E;  3P3E A;  4KHP E;  1PVG A;  4U3B A;  4JI5 E;  4AQY I;  4IFD D;  4IZK A;  3K85 A;  4NXM E;  2C38 A;  1ZM9 A;  1HNZ I;  2JE6 A;  3QT6 A;  3V2U C;  2JEB B;  1J5E E;  3ZZT A;  4YY3 I;  4RPF A;  2VQE I;  2GQ0 A;  2PO0 B; 
#chains in the Genus database with same CATH homology
 4MDT A;  1YH8 A;  3PS1 A;  4FW7 A;  4MQY A;  3UHM A;  1YHC A;  4J3D A;  2IES A;  4FW3 A;  2JT2 A;  3PS2 A;  4FW4 A;  2GO4 A;  5DRR A;  1XXE A;  5DRO A;  4ISA A;  3U1Y A;  3P3G A;  3P3E A;  4FW6 A;  5DRQ A;  4U3B A;  5DRP A;  3PS3 A;  4OZE A;  4LCF A;  4U3D A;  2O3Z A;  4IS9 A;  2GO3 A;  3P3C A;  4OKG A;  4LCG A;  3P76 A;  4FW5 A;  3NZK A;  1P42 A;  2J65 A;  2IER A;  2VES A;  4LCH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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