3P3GA

Crystal structure of the escherichia coli lpxc/lpc-009 complex
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
300
structure length
300
Chain Sequence
MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIPIMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTIDFNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEYVTFQDDAELPLAFKAP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 85
structure length 300
sequence length 300
ec nomenclature ec 3.5.1.-:
pdb deposition date 2010-10-04
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3p3gA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3p3gA02
1XXEA 3U1YA 5DRRA 5DROA 4ISAA 4MQYA 4FW6A 1P42A 4FW5A 2VESA 3P3CA 3P76A 4U3BA 5DRPA 2GO4A 4OZEA 4LCHA 3P3EA 4J3DA 2GO3A 4IS9A 4OKGA 3UHMA 4LCFA 1YH8A 4FW3A 2O3ZA 3NZKA 3PS1A 3PS3A 4FW7A 1YHCA 2J65A 4LCGA 4FW4A 5DRQA 2IERA 3PS2A 2IESA 4U3DA 4MDTA 3P3GA 2JT2A
chains in the Genus database with same CATH superfamily
3Q6MA 3B78A 4LFCE 1Z5CA 1I94I 3QT7A 4HACB 3J7AG 1S4EA 3CDJA 2XEXA 1S16A 3P3EA 1N34I 4DV2I 3QT8A 3Q6NA 3QT5A 4WUBA 1ZM4A 3D4JA 1N33I 4MU1A 2BA1G 2C38B 1VISA 4DV6E 5LMUI 2PO2B 4JI4I 4LF5I 2HHHI 3CDIA 4OO1C 4YHHE 1IBKE 3T1HI 5IT9Q 1DARA 1NHJA 3PYFA 3DD6A 2AE8A 2UU9I 5C0XF 3WU5A 4DV3I 3M7NG 2VQEE 2HKJA 4KHPE 1IBLE 3ZZTA 4LOMA 4X62E 4DUZI 4MU4A 1Z0VA 2WNRA 1Z0TA 5C0XA 5C0XE 4KQVA 4JI0E 4NXME 5JEAD 1N36I 4P7AA 4MYTA 1ZXMA 4NXNI 4DXLA 4JI8I 2A2DA 2R3VA 4IZJD 1Y4UA 1ZM3A 2F1DA 1Z0EA 1K47A 5GMDA 1FWKA 4LF4I 2VQFE 4IS9A 5LMNI 4LFBE 2ZM6E 2CZ9A 1MG7A 1UDQA 3J81C 3PS2A 2X36A 2WNRB 3H1CA 2NN6D 4LFAE 3LNUA 5C0XB 2V34A 4IZKA 2CGEA 1OYSA 2EFGA 1KKHA 4YHHI 1IBKI 4DV1I 2WW4A 1Z0GA 2PO1A 1XNRE 4Z7YA 3U1KA 1FI4A 2GO4A 2HFUA 4OKGA 1H73A 3ZZUA 1R6MA 2O1VA 1FJGE 3LPSA 4FW3A 4WUCA 3GLLA 1UDNA 2IOQA 1VI7A 1Z59A 4KHPI 3QT6A 4FW4A 4QNJA 4B3ME 3B82A 1IBME 4IFDD 4LF7I 2X7IA 4DR4E 4NXMI 4JI0I 4DU8A 2HK3A 4HACA 1J5EE 3J81Q 4URLA 4OO1A 5EKWA 4OO1E 1UDOA 4HXZA 3PRYA 1XMOI 1ZM9A 3PYGA 2C38A 4OX9E 3HJCA 5JEAC 5IT9C 1XNQE 1HK7A 2ZM6I 4X66I 5K36C 3J80Q 2GS8A 4QNKA 1H72C 4AIDA 1XNRI 4LCFA 4AQYE 4JV5E 4AIMA 4OO1B 3GMEA 2OI2A 3PS3A 1OYRA 4NBQA 2NN6C 1MU5A 4B3TI 4Z7CA 1FJGI 4JI5E 1RR9A 2IESA 4DR2E 2V2VA 4USKA 2PNZB 5FLXQ 4B3MI 4FN5A 2NPFA 4JI1E 4ISAA 2F4VI 5A2QQ 4UT4A 4PU9A 4DR7E 3B8HA 2JEAB 5ELWA 1J5EI 4MU3A 1NHIA 2C39B 4YY3E 1HR0E 4J3DA 4FWDA 3T1YI 2E5LE 4LF8E 4LPFA 1PIEA 2CVEA 1E3PA 4DV5E 5C0XD 4IFDC 2BM0A 2UUBE 3F0NA 2J65A 1Z0CA 3WU4A 3PYDA 1XNQI 1A6FA 4JI7I 1RREA 1ZM2A 4EMDA 1FNMA 1HNWE 3WU3A 4MQYA 4X64E 1N32E 2UXCE 4LFCI 3UHMA 4GKKE 4DR1E 3LTOA 1H74A 1B63A 3P06A 3J7AM 5LL6R 4LCGA 4AQYI 1Z5AA 4U3DA 4DPUA 4DV0E 2VF3A 4DV6I 5IWAE 4B3SE 4JI5I 1XXEA 2Z5EA 4DR2I 2ZITA 3ZZ0A 4WUDA 4JI1I 2DEJA 4DR7I 5K36A 5K36E 4PRVA 4LCHA 4LF9E 1KVKA 1PKPA 3J80C 3GONA 1Z0BA 4JI2E 2VQEI 4LF8I 2BA0D 1EI1A 4JG4A 1IBLI 2GQ0A 1XMQE 4X62I 4OO1F 3CWVA 2J7KA 1QZRA 2AJ4A 4USMA 2A2CA 2O1UA 3L7ZB 4DR3E 1XHKA 4AM3A 4FW6A 4DPXA 5JEAB 5DNLA 1HNWI 3K1JA 4DR6E 2BR2B 5FWKA 4DV7E 3JAMQ 2BM1A 2GO3A 4X64I 5LMUE 2JE6B 5FLXC 1N32I 4DUYE 4DU7A 4LF5E 1D6TA 2UXCI 1UEKA 5K36B 2VQFI 1KIJA 2PNZA 5A2QC 2C37A 4GKKI 2UUAE 4LFBI 4JYAE 2WP8B 3P3GA 2UXBE 4DV0I 5DRRA 5DROA 2JEAA 4DV3E 5IWAI 2C39A 4LFAI 2ZBKB 2Q2EB 3M85D 2NN6B 4DPYA 3OTOE 1H7UA 5GMEA 4JI6E 3K17A 4DV4E 4FWGA 4PRXA 4JI3E 3NZKA 2JEBA 4FW9A 4LF9I 4P52A 5L3JA 2HFSA 2IERA 2BA0G 1BKNA 1Y5YA 2C37B 5BR8E 3U1YA 2V2ZA 1XMQI 5DNXA 1WUUA 1IBMI 2R42A 4LF4E 1U2RA 4I3HA 5LMNE 1H7SA 4DR4I 2UUCE 4IFDB 4DR3I 1RHYA 2O1TA 2DEIA 1YH8A 2V8PA 1NHHA 1N0VC 4DR6I 4DV7I 4DUYI 4OX9I 4MDTA 4LF6E 2JEBB 4DV1E 3V2UC 4DR5E 2UUAI 2HK2A 4MYUA 2Z5CA 4JYAI 4BA1B 2Z5BB 3M6AA 4FW5A 3P3CA 3P76A 2UXBI 4X65E 2LJPA 1Y4SA 3M85G 4HY1A 2IOPA 4K0KE 2PNMA 2UXDE 1Y60A 2PO0A 1PVGA 3Q1QA 1KTVA 5JEAF 1ELOA 3OTOI 4JI6I 3K85A 3KRNA 4DV4I 4LF7E 1YHCA 4HYMA 3V5RA 4JV5I 3ZM7A 4JI3I 1HNXE 4GQUA 4R1FA 3L7ZA 5K36F 1OJ4A 4MU0A 3JAMC 5JEAA 5EL9A 5JEAE 2HKEA 1HNZE 1XMOE 4B3RE 1Z5BA 2BR2A 2V2QA 5K36D 2VESA 5BR8I 5DRPA 3H4LA 2JE6A 2Z5CB 4IZJA 1B62A 2UUCI 4GKJE 1ZXNA 4BA2A 2O3ZA 3PS1A 4X66E 2NN6F 4YY3I 1HR0I 2WP8A 2PO0B 4N3OA 2E5LI 4M1KA 4DV5I 3ZKBA 3HULA 2UUBI 1R6LA 1I94E 4LF6I 1Y6ZA 1FKAE 2NN6A 1E3HA 1Z0WA 2NN6E 4OO1D 4DR5I 1N34E 4DV2E 4ED4A 1USVA 3HKMA 5C0XC 1N33E 3B4TA 4B3TE 4X65I 2BA1D 4IZJB 4JI4E 1USUA 4K0KI 2HHHE 4IFDF 1MX0A 2UXDI 4UTGA 4FW7A 5DRQA 4DPWA 4RPFA 3T1HE 4DR1I 1FWLA 4BA2B 2CG9A 2F4VE 1NZ0A 3ZKDA 2O1WA 2JT2A 1HNXI 2UU9E 4DPTA 4IFDA 4IFDE 4XTJA 1P42A 3T1YE 4IZKB 4FWHA 4U3BA 4B3SI 3PYEA 3GCMA 1HNZI 3M7ND 4B3RI 2E1RA 4DUZE 2BV3A 4OZEA 1UDSA 2PO1B 2PO2A 1OYPA 4ZVIA 3WU6A 1N36E 4GKJI 1EA6A 4JI7E 2PNLA 4NXNE 4JI8E 1N0UA 4BA1A 4JI2I 2Z5BA
chains in the Genus database with same CATH topology
1XXEA 3U1YA 5DRRA 5DROA 4ISAA 4MQYA 4FW6A 1P42A 4FW5A 2VESA 3P3CA 3P76A 4U3BA 5DRPA 2GO4A 4OZEA 4LCHA 3P3EA 4J3DA 2GO3A 4IS9A 4OKGA 3UHMA 4LCFA 1YH8A 4FW3A 2O3ZA 3NZKA 3PS1A 3PS3A 4FW7A 1YHCA 2J65A 4LCGA 4FW4A 5DRQA 2IERA 3PS2A 2IESA 4U3DA 4MDTA 3P3GA 2JT2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XXE A;  3U1Y A;  5DRR A;  5DRO A;  4ISA A;  4MQY A;  4FW6 A;  1P42 A;  4FW5 A;  2VES A;  3P3C A;  3P76 A;  4U3B A;  5DRP A;  2GO4 A;  4OZE A;  4LCH A;  3P3E A;  4J3D A;  2GO3 A;  4IS9 A;  4OKG A;  3UHM A;  4LCF A;  1YH8 A;  4FW3 A;  2O3Z A;  3NZK A;  3PS1 A;  3PS3 A;  4FW7 A;  1YHC A;  2J65 A;  4LCG A;  4FW4 A;  5DRQ A;  2IER A;  3PS2 A;  2IES A;  4U3D A;  4MDT A;  3P3G A;  2JT2 A; 
#chains in the Genus database with same CATH topology
 3Q6M A;  3B78 A;  4LFC E;  1Z5C A;  1I94 I;  3QT7 A;  4HAC B;  3J7A G;  1S4E A;  3CDJ A;  2XEX A;  1S16 A;  3P3E A;  1N34 I;  4DV2 I;  3QT8 A;  3Q6N A;  3QT5 A;  4WUB A;  1ZM4 A;  3D4J A;  1N33 I;  4MU1 A;  2BA1 G;  2C38 B;  1VIS A;  4DV6 E;  5LMU I;  2PO2 B;  4JI4 I;  4LF5 I;  2HHH I;  3CDI A;  4OO1 C;  4YHH E;  1IBK E;  3T1H I;  5IT9 Q;  1DAR A;  1NHJ A;  3PYF A;  3DD6 A;  2AE8 A;  2UU9 I;  5C0X F;  3WU5 A;  4DV3 I;  3M7N G;  2VQE E;  2HKJ A;  4KHP E;  1IBL E;  3ZZT A;  4LOM A;  4X62 E;  4DUZ I;  4MU4 A;  1Z0V A;  2WNR A;  1Z0T A;  5C0X A;  5C0X E;  4KQV A;  4JI0 E;  4NXM E;  5JEA D;  1N36 I;  4P7A A;  4MYT A;  1ZXM A;  4NXN I;  4DXL A;  4JI8 I;  2A2D A;  2R3V A;  4IZJ D;  1Y4U A;  1ZM3 A;  2F1D A;  1Z0E A;  1K47 A;  5GMD A;  1FWK A;  4LF4 I;  2VQF E;  4IS9 A;  5LMN I;  4LFB E;  2ZM6 E;  2CZ9 A;  1MG7 A;  1UDQ A;  3J81 C;  3PS2 A;  2X36 A;  2WNR B;  3H1C A;  2NN6 D;  4LFA E;  3LNU A;  5C0X B;  2V34 A;  4IZK A;  2CGE A;  1OYS A;  2EFG A;  1KKH A;  4YHH I;  1IBK I;  4DV1 I;  2WW4 A;  1Z0G A;  2PO1 A;  1XNR E;  4Z7Y A;  3U1K A;  1FI4 A;  2GO4 A;  2HFU A;  4OKG A;  1H73 A;  3ZZU A;  1R6M A;  2O1V A;  1FJG E;  3LPS A;  4FW3 A;  4WUC A;  3GLL A;  1UDN A;  2IOQ A;  1VI7 A;  1Z59 A;  4KHP I;  3QT6 A;  4FW4 A;  4QNJ A;  4B3M E;  3B82 A;  1IBM E;  4IFD D;  4LF7 I;  2X7I A;  4DR4 E;  4NXM I;  4JI0 I;  4DU8 A;  2HK3 A;  4HAC A;  1J5E E;  3J81 Q;  4URL A;  4OO1 A;  5EKW A;  4OO1 E;  1UDO A;  4HXZ A;  3PRY A;  1XMO I;  1ZM9 A;  3PYG A;  2C38 A;  4OX9 E;  3HJC A;  5JEA C;  5IT9 C;  1XNQ E;  1HK7 A;  2ZM6 I;  4X66 I;  5K36 C;  3J80 Q;  2GS8 A;  4QNK A;  1H72 C;  4AID A;  1XNR I;  4LCF A;  4AQY E;  4JV5 E;  4AIM A;  4OO1 B;  3GME A;  2OI2 A;  3PS3 A;  1OYR A;  4NBQ A;  2NN6 C;  1MU5 A;  4B3T I;  4Z7C A;  1FJG I;  4JI5 E;  1RR9 A;  2IES A;  4DR2 E;  2V2V A;  4USK A;  2PNZ B;  5FLX Q;  4B3M I;  4FN5 A;  2NPF A;  4JI1 E;  4ISA A;  2F4V I;  5A2Q Q;  4UT4 A;  4PU9 A;  4DR7 E;  3B8H A;  2JEA B;  5ELW A;  1J5E I;  4MU3 A;  1NHI A;  2C39 B;  4YY3 E;  1HR0 E;  4J3D A;  4FWD A;  3T1Y I;  2E5L E;  4LF8 E;  4LPF A;  1PIE A;  2CVE A;  1E3P A;  4DV5 E;  5C0X D;  4IFD C;  2BM0 A;  2UUB E;  3F0N A;  2J65 A;  1Z0C A;  3WU4 A;  3PYD A;  1XNQ I;  1A6F A;  4JI7 I;  1RRE A;  1ZM2 A;  4EMD A;  1FNM A;  1HNW E;  3WU3 A;  4MQY A;  4X64 E;  1N32 E;  2UXC E;  4LFC I;  3UHM A;  4GKK E;  4DR1 E;  3LTO A;  1H74 A;  1B63 A;  3P06 A;  3J7A M;  5LL6 R;  4LCG A;  4AQY I;  1Z5A A;  4U3D A;  4DPU A;  4DV0 E;  2VF3 A;  4DV6 I;  5IWA E;  4B3S E;  4JI5 I;  1XXE A;  2Z5E A;  4DR2 I;  2ZIT A;  3ZZ0 A;  4WUD A;  4JI1 I;  2DEJ A;  4DR7 I;  5K36 A;  5K36 E;  4PRV A;  4LCH A;  4LF9 E;  1KVK A;  1PKP A;  3J80 C;  3GON A;  1Z0B A;  4JI2 E;  2VQE I;  4LF8 I;  2BA0 D;  1EI1 A;  4JG4 A;  1IBL I;  2GQ0 A;  1XMQ E;  4X62 I;  4OO1 F;  3CWV A;  2J7K A;  1QZR A;  2AJ4 A;  4USM A;  2A2C A;  2O1U A;  3L7Z B;  4DR3 E;  1XHK A;  4AM3 A;  4FW6 A;  4DPX A;  5JEA B;  5DNL A;  1HNW I;  3K1J A;  4DR6 E;  2BR2 B;  5FWK A;  4DV7 E;  3JAM Q;  2BM1 A;  2GO3 A;  4X64 I;  5LMU E;  2JE6 B;  5FLX C;  1N32 I;  4DUY E;  4DU7 A;  4LF5 E;  1D6T A;  2UXC I;  1UEK A;  5K36 B;  2VQF I;  1KIJ A;  2PNZ A;  5A2Q C;  2C37 A;  4GKK I;  2UUA E;  4LFB I;  4JYA E;  2WP8 B;  3P3G A;  2UXB E;  4DV0 I;  5DRR A;  5DRO A;  2JEA A;  4DV3 E;  5IWA I;  2C39 A;  4LFA I;  2ZBK B;  2Q2E B;  3M85 D;  2NN6 B;  4DPY A;  3OTO E;  1H7U A;  5GME A;  4JI6 E;  3K17 A;  4DV4 E;  4FWG A;  4PRX A;  4JI3 E;  3NZK A;  2JEB A;  4FW9 A;  4LF9 I;  4P52 A;  5L3J A;  2HFS A;  2IER A;  2BA0 G;  1BKN A;  1Y5Y A;  2C37 B;  5BR8 E;  3U1Y A;  2V2Z A;  1XMQ I;  5DNX A;  1WUU A;  1IBM I;  2R42 A;  4LF4 E;  1U2R A;  4I3H A;  5LMN E;  1H7S A;  4DR4 I;  2UUC E;  4IFD B;  4DR3 I;  1RHY A;  2O1T A;  2DEI A;  1YH8 A;  2V8P A;  1NHH A;  1N0V C;  4DR6 I;  4DV7 I;  4DUY I;  4OX9 I;  4MDT A;  4LF6 E;  2JEB B;  4DV1 E;  3V2U C;  4DR5 E;  2UUA I;  2HK2 A;  4MYU A;  2Z5C A;  4JYA I;  4BA1 B;  2Z5B B;  3M6A A;  4FW5 A;  3P3C A;  3P76 A;  2UXB I;  4X65 E;  2LJP A;  1Y4S A;  3M85 G;  4HY1 A;  2IOP A;  4K0K E;  2PNM A;  2UXD E;  1Y60 A;  2PO0 A;  1PVG A;  3Q1Q A;  1KTV A;  5JEA F;  1ELO A;  3OTO I;  4JI6 I;  3K85 A;  3KRN A;  4DV4 I;  4LF7 E;  1YHC A;  4HYM A;  3V5R A;  4JV5 I;  3ZM7 A;  4JI3 I;  1HNX E;  4GQU A;  4R1F A;  3L7Z A;  5K36 F;  1OJ4 A;  4MU0 A;  3JAM C;  5JEA A;  5EL9 A;  5JEA E;  2HKE A;  1HNZ E;  1XMO E;  4B3R E;  1Z5B A;  2BR2 A;  2V2Q A;  5K36 D;  2VES A;  5BR8 I;  5DRP A;  3H4L A;  2JE6 A;  2Z5C B;  4IZJ A;  1B62 A;  2UUC I;  4GKJ E;  1ZXN A;  4BA2 A;  2O3Z A;  3PS1 A;  4X66 E;  2NN6 F;  4YY3 I;  1HR0 I;  2WP8 A;  2PO0 B;  4N3O A;  2E5L I;  4M1K A;  4DV5 I;  3ZKB A;  3HUL A;  2UUB I;  1R6L A;  1I94 E;  4LF6 I;  1Y6Z A;  1FKA E;  2NN6 A;  1E3H A;  1Z0W A;  2NN6 E;  4OO1 D;  4DR5 I;  1N34 E;  4DV2 E;  4ED4 A;  1USV A;  3HKM A;  5C0X C;  1N33 E;  3B4T A;  4B3T E;  4X65 I;  2BA1 D;  4IZJ B;  4JI4 E;  1USU A;  4K0K I;  2HHH E;  4IFD F;  1MX0 A;  2UXD I;  4UTG A;  4FW7 A;  5DRQ A;  4DPW A;  4RPF A;  3T1H E;  4DR1 I;  1FWL A;  4BA2 B;  2CG9 A;  2F4V E;  1NZ0 A;  3ZKD A;  2O1W A;  2JT2 A;  1HNX I;  2UU9 E;  4DPT A;  4IFD A;  4IFD E;  4XTJ A;  1P42 A;  3T1Y E;  4IZK B;  4FWH A;  4U3B A;  4B3S I;  3PYE A;  3GCM A;  1HNZ I;  3M7N D;  4B3R I;  2E1R A;  4DUZ E;  2BV3 A;  4OZE A;  1UDS A;  2PO1 B;  2PO2 A;  1OYP A;  4ZVI A;  3WU6 A;  1N36 E;  4GKJ I;  1EA6 A;  4JI7 E;  2PNL A;  4NXN E;  4JI8 E;  1N0U A;  4BA1 A;  4JI2 I;  2Z5B A; 
#chains in the Genus database with same CATH homology
 1XXE A;  3U1Y A;  5DRR A;  5DRO A;  4ISA A;  4MQY A;  4FW6 A;  1P42 A;  4FW5 A;  2VES A;  3P3C A;  3P76 A;  4U3B A;  5DRP A;  2GO4 A;  4OZE A;  4LCH A;  3P3E A;  4J3D A;  2GO3 A;  4IS9 A;  4OKG A;  3UHM A;  4LCF A;  1YH8 A;  4FW3 A;  2O3Z A;  3NZK A;  3PS1 A;  3PS3 A;  4FW7 A;  1YHC A;  2J65 A;  4LCG A;  4FW4 A;  5DRQ A;  2IER A;  3PS2 A;  2IES A;  4U3D A;  4MDT A;  3P3G A;  2JT2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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