3P3CA

Crystal structure of the aquifex aeolicus lpxc/lpc-009 complex
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
272
structure length
272
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQKLTRDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
pubmed doi rcsb
source organism Aquifex aeolicus
total genus 86
structure length 272
sequence length 272
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3p3cA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3p3cA02
3PS2A 4FW5A 5DRPA 4FW3A 3P3CA 2VESA 4ISAA 3PS3A 4FW4A 5DROA 3PS1A 4FW7A 2O3ZA 4OKGA 1YH8A 4U3DA 3NZKA 5DRQA 2GO4A 4LCGA 3P76A 3UHMA 2JT2A 4FW6A 2GO3A 4IS9A 3U1YA 4OZEA 1P42A 4MDTA 3P3GA 2IERA 4LCFA 4LCHA 1XXEA 3P3EA 2IESA 5DRRA 4J3DA 2J65A 4MQYA 4U3BA 1YHCA
chains in the Genus database with same CATH superfamily
3PS2A 4URLA 3JAMQ 4BA1B 3LNUA 4DV7E 4IFDF 1FNMA 4LF6I 4DR5E 4IS9A 4LCFA 4WUCA 1XXEA 1H7SA 4YHHE 3U1KA 5IT9C 1DARA 3QT7A 4JI8E 3GONA 2PNLA 2UXDI 4HYMA 3ZKDA 1IBLI 2PO2A 2NN6D 4LFCI 5K36D 2F4VI 1ZM3A 2UUCE 4DU7A 5LL6R 4DV2E 4LFBI 2O1VA 2C37B 3QT6A 5IWAE 4DV0I 2J7KA 2UUAE 4DV5I 4JV5I 4M1KA 5JEAF 4DR3I 4MQYA 2UXCE 4DPTA 1UDNA 4IFDD 4JI7I 4B3SE 4JYAE 2AE8A 4FW3A 5GMEA 4ISAA 4I3HA 3ZM7A 4DPWA 2PNZB 4DV4E 3KRNA 3HJCA 3WU5A 2GO4A 4DR6E 1Z0BA 4NBQA 2V8PA 2PO0A 2WP8B 2HHHE 5K36C 3CDIA 2BV3A 4X65I 5FLXQ 5C0XF 4AM3A 2GQ0A 2CVEA 4B3TI 1I94I 4IZKB 2VQFI 3Q1QA 4GKKI 3J80Q 3J7AG 2DEIA 2ZITA 5DRPA 2C39A 2BM1A 1MU5A 3P3CA 4KQVA 4USKA 4P52A 4B3RE 4FW7A 5K36A 1NHIA 5JEAD 3B8HA 3HKMA 1N34I 1IBMI 1FWKA 4DPUA 4AQYI 4DV6I 2JEBB 1J5EI 1IBLE 2E1RA 2F4VE 3GLLA 4B3ME 2BA1G 2J65A 4DPYA 3ZZUA 5K36E 3PYGA 4DPXA 3T1HI 4X66I 2BA0G 3M85D 4DV3I 2NN6B 1HK7A 4DV0E 1RHYA 1XHKA 1KVKA 1HR0I 4OX9I 4JV5E 4OKGA 4ZVIA 2LJPA 4BA1A 4DUYE 4JI7E 1RREA 4JG4A 1IBKI 1XNQI 4LF9E 2VQEI 4NXMI 1USUA 4QNJA 4BA2B 3WU6A 4LPFA 4KHPI 4PRVA 1NHJA 1XMOI 3WU4A 1E3HA 1WUUA 4IFDB 1FJGI 4NXNI 5FWKA 1H73A 2WNRB 3J81C 1K47A 1Z59A 5LMNI 3PS3A 5DNLA 3ZKBA 3ZZTA 4AIMA 4JI3E 1I94E 2VQFE 4GKKE 1VISA 4UTGA 2HFUA 4DUZI 3T1YI 2HFSA 5DNXA 2A2CA 2O1TA 2C37A 3P3EA 1N0UA 4LFAI 4JI5I 4X64E 1UDOA 4JI4E 3PYFA 4OO1D 2Z5EA 1N34E 4JI6I 1N36I 1U2RA 1D6TA 4DV6E 4JI2E 5JEAE 1J5EE 5IT9Q 5JEAB 1KKHA 2IOPA 1OYPA 1Z5AA 1N33I 4AIDA 3P76A 1E3PA 2PNZA 3M85G 4DV3E 1FWLA 3PRYA 5ELWA 1BKNA 3F0NA 1MG7A 2WP8A 1HR0E 1XNRI 4DV1I 3DD6A 4Z7CA 1ZXNA 5EL9A 3UHMA 1XMQI 3HULA 4IZKA 1ZXMA 1IBKE 1XNQE 2VQEE 1KIJA 2NPFA 5C0XB 4PU9A 1PKPA 3M7ND 1XMOE 4LCGA 4DR7I 4HACB 2IOQA 2NN6C 3K85A 1FJGE 1NHHA 2C38B 4NXNE 3B82A 5A2QC 2JEBA 4FWDA 5LMNE 4DR2I 4LF7I 4FWGA 3ZZ0A 4X62I 1FI4A 4DUZE 4LF6E 2Z5BB 1Z5CA 4FW5A 4LF5I 4GKJI 3CDJA 2WW4A 2NN6A 4LFAE 3PYDA 2UU9I 2O3ZA 2O1UA 4MU4A 4DXLA 4U3DA 1Z0VA 3NZKA 4IFDC 4JI6E 2UXDE 2EFGA 4GQUA 1RR9A 1FKAE 4OO1E 2JE6B 2PO1B 4LFCE 2JEAA 2IESA 4MU1A 1HNZI 2R42A 2NN6E 3CWVA 4Z7YA 4BA2A 4OO1B 1Z0WA 3QT8A 2CZ9A 4LFBE 2HK2A 4YHHI 4IFDA 4HY1A 4WUDA 2WNRA 1QZRA 4JI8I 3PS1A 4DV5E 1XNRE 2GS8A 5C0XD 4DR3E 2DEJA 2JT2A 3H4LA 4FW6A 3V5RA 4DR4I 2Z5CB 2UXBI 1R6LA 1H74A 2X7IA 2CGEA 2JEAB 1PIEA 2UUCI 1S16A 4IFDE 5JEAC 3PYEA 1UDQA 4DV2I 4EMDA 1Z0TA 4XTJA 3M7NG 4MU0A 4FN5A 4DR7E 1HNWI 1YHCA 2HKEA 4MDTA 1ELOA 2BM0A 4MYTA 2XEXA 2O1WA 4X65E 4DR2E 2UXCI 4LF7E 1UEKA 4B3TE 5EKWA 3K1JA 5JEAA 1KTVA 4JYAI 1OYSA 5K36F 1Y60A 3GCMA 2E5LI 4GKJE 1OJ4A 1USVA 1ZM2A 5C0XC 2VF3A 2X36A 4JI0I 2UU9E 3JAMC 4DR1I 4DR6I 1Z0GA 3GMEA 4R1FA 1IBME 4IZJB 4AQYE 1EI1A 3OTOI 4USMA 2OI2A 4LF4I 1B62A 2BR2B 4PRXA 5LMUI 1HNZE 2F1DA 4HXZA 5C0XA 3T1HE 2GO3A 4X66E 3L7ZB 2PNMA 2ZM6I 1Z0EA 2IERA 4HACA 4B3RI 2C38A 4OX9E 5DRRA 4RPFA 3P06A 4DR4E 2V2VA 5C0XE 2UXBE 1ZM4A 4NXME 1H7UA 2AJ4A 2Z5BA 3WU3A 4B3MI 4MYUA 3H1CA 4FW4A 2BA1D 5BR8I 4OO1C 3QT5A 4KHPE 5DRQA 2BA0D 4N3OA 5GMDA 1HNWE 1N0VC 4P7AA 1P42A 3P3GA 4LOMA 4QNKA 2JE6A 2PO1A 4JI1I 2PO2B 1R6MA 1NZ0A 4DUYI 1Y4UA 2HK3A 3Q6MA 1UDSA 4LF9I 4OO1A 3T1YE 5A2QQ 1N32I 4IZJD 2UUBI 2ZBKB 4FWHA 1HNXI 2E5LE 4YY3I 4LF8I 1Y5YA 1B63A 5DROA 5FLXC 2V2QA 4JI0E 4JI5E 4DR1E 4FW9A 4K0KI 4WUBA 1N36E 4OZEA 3J80C 3OTOE 3B78A 2Z5CA 1Z5BA 4LF4E 4JI3I 3J7AM 5LMUE 4DV7I 4DR5I 1N33E 1VI7A 2ZM6E 1S4EA 2VESA 4X64I 4JI4I 1Y4SA 2V34A 1YH8A 1Z0CA 1Y6ZA 3Q6NA 2PO0B 4DV1E 2Q2EB 4JI2I 3U1YA 2V2ZA 1XMQE 3V2UC 4LCHA 4J3DA 5BR8E 4U3BA 2HKJA 3LTOA 1MX0A 2C39B 5IWAI 4MU3A 3LPSA 3B4TA 4ED4A 1ZM9A 2UUAI 5K36B 3K17A 4IZJA 4OO1F 1H72C 4JI1E 1EA6A 2BR2A 4UT4A 2NN6F 4B3SI 3M6AA 4X62E 3J81Q 2R3VA 2UUBE 1N32E 1HNXE 4LF5E 3L7ZA 5L3JA 4YY3E 4LF8E 1A6FA 1PVGA 4DV4I 2A2DA 4K0KE 3D4JA 4DU8A 2HHHI 2CG9A 1OYRA
chains in the Genus database with same CATH topology
3PS2A 4FW5A 5DRPA 4FW3A 3P3CA 2VESA 4ISAA 3PS3A 4FW4A 5DROA 3PS1A 4FW7A 2O3ZA 4OKGA 1YH8A 4U3DA 3NZKA 5DRQA 2GO4A 4LCGA 3P76A 3UHMA 2JT2A 4FW6A 2GO3A 4IS9A 3U1YA 4OZEA 1P42A 4MDTA 3P3GA 2IERA 4LCFA 4LCHA 1XXEA 3P3EA 2IESA 5DRRA 4J3DA 2J65A 4MQYA 4U3BA 1YHCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PS2 A;  4FW5 A;  5DRP A;  4FW3 A;  3P3C A;  2VES A;  4ISA A;  3PS3 A;  4FW4 A;  5DRO A;  3PS1 A;  4FW7 A;  2O3Z A;  4OKG A;  1YH8 A;  4U3D A;  3NZK A;  5DRQ A;  2GO4 A;  4LCG A;  3P76 A;  3UHM A;  2JT2 A;  4FW6 A;  2GO3 A;  4IS9 A;  3U1Y A;  4OZE A;  1P42 A;  4MDT A;  3P3G A;  2IER A;  4LCF A;  4LCH A;  1XXE A;  3P3E A;  2IES A;  5DRR A;  4J3D A;  2J65 A;  4MQY A;  4U3B A;  1YHC A; 
#chains in the Genus database with same CATH topology
 3PS2 A;  4URL A;  3JAM Q;  4BA1 B;  3LNU A;  4DV7 E;  4IFD F;  1FNM A;  4LF6 I;  4DR5 E;  4IS9 A;  4LCF A;  4WUC A;  1XXE A;  1H7S A;  4YHH E;  3U1K A;  5IT9 C;  1DAR A;  3QT7 A;  4JI8 E;  3GON A;  2PNL A;  2UXD I;  4HYM A;  3ZKD A;  1IBL I;  2PO2 A;  2NN6 D;  4LFC I;  5K36 D;  2F4V I;  1ZM3 A;  2UUC E;  4DU7 A;  5LL6 R;  4DV2 E;  4LFB I;  2O1V A;  2C37 B;  3QT6 A;  5IWA E;  4DV0 I;  2J7K A;  2UUA E;  4DV5 I;  4JV5 I;  4M1K A;  5JEA F;  4DR3 I;  4MQY A;  2UXC E;  4DPT A;  1UDN A;  4IFD D;  4JI7 I;  4B3S E;  4JYA E;  2AE8 A;  4FW3 A;  5GME A;  4ISA A;  4I3H A;  3ZM7 A;  4DPW A;  2PNZ B;  4DV4 E;  3KRN A;  3HJC A;  3WU5 A;  2GO4 A;  4DR6 E;  1Z0B A;  4NBQ A;  2V8P A;  2PO0 A;  2WP8 B;  2HHH E;  5K36 C;  3CDI A;  2BV3 A;  4X65 I;  5FLX Q;  5C0X F;  4AM3 A;  2GQ0 A;  2CVE A;  4B3T I;  1I94 I;  4IZK B;  2VQF I;  3Q1Q A;  4GKK I;  3J80 Q;  3J7A G;  2DEI A;  2ZIT A;  5DRP A;  2C39 A;  2BM1 A;  1MU5 A;  3P3C A;  4KQV A;  4USK A;  4P52 A;  4B3R E;  4FW7 A;  5K36 A;  1NHI A;  5JEA D;  3B8H A;  3HKM A;  1N34 I;  1IBM I;  1FWK A;  4DPU A;  4AQY I;  4DV6 I;  2JEB B;  1J5E I;  1IBL E;  2E1R A;  2F4V E;  3GLL A;  4B3M E;  2BA1 G;  2J65 A;  4DPY A;  3ZZU A;  5K36 E;  3PYG A;  4DPX A;  3T1H I;  4X66 I;  2BA0 G;  3M85 D;  4DV3 I;  2NN6 B;  1HK7 A;  4DV0 E;  1RHY A;  1XHK A;  1KVK A;  1HR0 I;  4OX9 I;  4JV5 E;  4OKG A;  4ZVI A;  2LJP A;  4BA1 A;  4DUY E;  4JI7 E;  1RRE A;  4JG4 A;  1IBK I;  1XNQ I;  4LF9 E;  2VQE I;  4NXM I;  1USU A;  4QNJ A;  4BA2 B;  3WU6 A;  4LPF A;  4KHP I;  4PRV A;  1NHJ A;  1XMO I;  3WU4 A;  1E3H A;  1WUU A;  4IFD B;  1FJG I;  4NXN I;  5FWK A;  1H73 A;  2WNR B;  3J81 C;  1K47 A;  1Z59 A;  5LMN I;  3PS3 A;  5DNL A;  3ZKB A;  3ZZT A;  4AIM A;  4JI3 E;  1I94 E;  2VQF E;  4GKK E;  1VIS A;  4UTG A;  2HFU A;  4DUZ I;  3T1Y I;  2HFS A;  5DNX A;  2A2C A;  2O1T A;  2C37 A;  3P3E A;  1N0U A;  4LFA I;  4JI5 I;  4X64 E;  1UDO A;  4JI4 E;  3PYF A;  4OO1 D;  2Z5E A;  1N34 E;  4JI6 I;  1N36 I;  1U2R A;  1D6T A;  4DV6 E;  4JI2 E;  5JEA E;  1J5E E;  5IT9 Q;  5JEA B;  1KKH A;  2IOP A;  1OYP A;  1Z5A A;  1N33 I;  4AID A;  3P76 A;  1E3P A;  2PNZ A;  3M85 G;  4DV3 E;  1FWL A;  3PRY A;  5ELW A;  1BKN A;  3F0N A;  1MG7 A;  2WP8 A;  1HR0 E;  1XNR I;  4DV1 I;  3DD6 A;  4Z7C A;  1ZXN A;  5EL9 A;  3UHM A;  1XMQ I;  3HUL A;  4IZK A;  1ZXM A;  1IBK E;  1XNQ E;  2VQE E;  1KIJ A;  2NPF A;  5C0X B;  4PU9 A;  1PKP A;  3M7N D;  1XMO E;  4LCG A;  4DR7 I;  4HAC B;  2IOQ A;  2NN6 C;  3K85 A;  1FJG E;  1NHH A;  2C38 B;  4NXN E;  3B82 A;  5A2Q C;  2JEB A;  4FWD A;  5LMN E;  4DR2 I;  4LF7 I;  4FWG A;  3ZZ0 A;  4X62 I;  1FI4 A;  4DUZ E;  4LF6 E;  2Z5B B;  1Z5C A;  4FW5 A;  4LF5 I;  4GKJ I;  3CDJ A;  2WW4 A;  2NN6 A;  4LFA E;  3PYD A;  2UU9 I;  2O3Z A;  2O1U A;  4MU4 A;  4DXL A;  4U3D A;  1Z0V A;  3NZK A;  4IFD C;  4JI6 E;  2UXD E;  2EFG A;  4GQU A;  1RR9 A;  1FKA E;  4OO1 E;  2JE6 B;  2PO1 B;  4LFC E;  2JEA A;  2IES A;  4MU1 A;  1HNZ I;  2R42 A;  2NN6 E;  3CWV A;  4Z7Y A;  4BA2 A;  4OO1 B;  1Z0W A;  3QT8 A;  2CZ9 A;  4LFB E;  2HK2 A;  4YHH I;  4IFD A;  4HY1 A;  4WUD A;  2WNR A;  1QZR A;  4JI8 I;  3PS1 A;  4DV5 E;  1XNR E;  2GS8 A;  5C0X D;  4DR3 E;  2DEJ A;  2JT2 A;  3H4L A;  4FW6 A;  3V5R A;  4DR4 I;  2Z5C B;  2UXB I;  1R6L A;  1H74 A;  2X7I A;  2CGE A;  2JEA B;  1PIE A;  2UUC I;  1S16 A;  4IFD E;  5JEA C;  3PYE A;  1UDQ A;  4DV2 I;  4EMD A;  1Z0T A;  4XTJ A;  3M7N G;  4MU0 A;  4FN5 A;  4DR7 E;  1HNW I;  1YHC A;  2HKE A;  4MDT A;  1ELO A;  2BM0 A;  4MYT A;  2XEX A;  2O1W A;  4X65 E;  4DR2 E;  2UXC I;  4LF7 E;  1UEK A;  4B3T E;  5EKW A;  3K1J A;  5JEA A;  1KTV A;  4JYA I;  1OYS A;  5K36 F;  1Y60 A;  3GCM A;  2E5L I;  4GKJ E;  1OJ4 A;  1USV A;  1ZM2 A;  5C0X C;  2VF3 A;  2X36 A;  4JI0 I;  2UU9 E;  3JAM C;  4DR1 I;  4DR6 I;  1Z0G A;  3GME A;  4R1F A;  1IBM E;  4IZJ B;  4AQY E;  1EI1 A;  3OTO I;  4USM A;  2OI2 A;  4LF4 I;  1B62 A;  2BR2 B;  4PRX A;  5LMU I;  1HNZ E;  2F1D A;  4HXZ A;  5C0X A;  3T1H E;  2GO3 A;  4X66 E;  3L7Z B;  2PNM A;  2ZM6 I;  1Z0E A;  2IER A;  4HAC A;  4B3R I;  2C38 A;  4OX9 E;  5DRR A;  4RPF A;  3P06 A;  4DR4 E;  2V2V A;  5C0X E;  2UXB E;  1ZM4 A;  4NXM E;  1H7U A;  2AJ4 A;  2Z5B A;  3WU3 A;  4B3M I;  4MYU A;  3H1C A;  4FW4 A;  2BA1 D;  5BR8 I;  4OO1 C;  3QT5 A;  4KHP E;  5DRQ A;  2BA0 D;  4N3O A;  5GMD A;  1HNW E;  1N0V C;  4P7A A;  1P42 A;  3P3G A;  4LOM A;  4QNK A;  2JE6 A;  2PO1 A;  4JI1 I;  2PO2 B;  1R6M A;  1NZ0 A;  4DUY I;  1Y4U A;  2HK3 A;  3Q6M A;  1UDS A;  4LF9 I;  4OO1 A;  3T1Y E;  5A2Q Q;  1N32 I;  4IZJ D;  2UUB I;  2ZBK B;  4FWH A;  1HNX I;  2E5L E;  4YY3 I;  4LF8 I;  1Y5Y A;  1B63 A;  5DRO A;  5FLX C;  2V2Q A;  4JI0 E;  4JI5 E;  4DR1 E;  4FW9 A;  4K0K I;  4WUB A;  1N36 E;  4OZE A;  3J80 C;  3OTO E;  3B78 A;  2Z5C A;  1Z5B A;  4LF4 E;  4JI3 I;  3J7A M;  5LMU E;  4DV7 I;  4DR5 I;  1N33 E;  1VI7 A;  2ZM6 E;  1S4E A;  2VES A;  4X64 I;  4JI4 I;  1Y4S A;  2V34 A;  1YH8 A;  1Z0C A;  1Y6Z A;  3Q6N A;  2PO0 B;  4DV1 E;  2Q2E B;  4JI2 I;  3U1Y A;  2V2Z A;  1XMQ E;  3V2U C;  4LCH A;  4J3D A;  5BR8 E;  4U3B A;  2HKJ A;  3LTO A;  1MX0 A;  2C39 B;  5IWA I;  4MU3 A;  3LPS A;  3B4T A;  4ED4 A;  1ZM9 A;  2UUA I;  5K36 B;  3K17 A;  4IZJ A;  4OO1 F;  1H72 C;  4JI1 E;  1EA6 A;  2BR2 A;  4UT4 A;  2NN6 F;  4B3S I;  3M6A A;  4X62 E;  3J81 Q;  2R3V A;  2UUB E;  1N32 E;  1HNX E;  4LF5 E;  3L7Z A;  5L3J A;  4YY3 E;  4LF8 E;  1A6F A;  1PVG A;  4DV4 I;  2A2D A;  4K0K E;  3D4J A;  4DU8 A;  2HHH I;  2CG9 A;  1OYR A; 
#chains in the Genus database with same CATH homology
 3PS2 A;  4FW5 A;  5DRP A;  4FW3 A;  3P3C A;  2VES A;  4ISA A;  3PS3 A;  4FW4 A;  5DRO A;  3PS1 A;  4FW7 A;  2O3Z A;  4OKG A;  1YH8 A;  4U3D A;  3NZK A;  5DRQ A;  2GO4 A;  4LCG A;  3P76 A;  3UHM A;  2JT2 A;  4FW6 A;  2GO3 A;  4IS9 A;  3U1Y A;  4OZE A;  1P42 A;  4MDT A;  3P3G A;  2IER A;  4LCF A;  4LCH A;  1XXE A;  3P3E A;  2IES A;  5DRR A;  4J3D A;  2J65 A;  4MQY A;  4U3B A;  1YHC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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