3P3CA

Crystal structure of the aquifex aeolicus lpxc/lpc-009 complex
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
272
structure length
272
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQKLTRDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
publication title Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.
pubmed doi rcsb
source organism Aquifex aeolicus
molecule tags Hydrolase
total genus 86
structure length 272
sequence length 272
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2010-10-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 3p3cA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 3p3cA02
5DRRA 4FW4A 1XXEA 4U3DA 2GO3A 4U3BA 5DRQA 4FW7A 4LCFA 1P42A 3P3CA 2IESA 2GO4A 2IERA 3NZKA 3P3GA 4FW6A 3PS3A 1YHCA 4FW5A 4J3DA 5DRPA 4OKGA 2JT2A 4MQYA 3P76A 4OZEA 3PS2A 3UHMA 4FW3A 4LCHA 3P3EA 5DROA 1YH8A 4MDTA 2J65A 2O3ZA 4IS9A 4LCGA 3U1YA 3PS1A 4ISAA 2VESA
chains in the Genus database with same CATH superfamily
5DRRA 2NPFA 4DPUA 4KHPI 1Z0GA 5IWAE 1FNMA 4HYMA 3WU6A 1H7UA 4DV2E 1EI1A 5K36D 2EFGA 1UDNA 2UXDE 4HACB 3D4JA 1PKPA 3B82A 2PNZB 4FW6A 1XMOI 5FWKA 5K36B 5LMNI 2R3VA 1HNZE 4DR2E 1HNXE 3ZKBA 4OZEA 2JEBB 2HK3A 4KQVA 5C0XE 4LFAE 1YH8A 4B3MI 3PS1A 2NN6F 4DR5E 5EL9A 3L7ZB 4NXNE 2NN6C 4FWHA 5GMEA 4B3SE 4JI1E 3P3CA 4DV6I 1E3PA 1Z0CA 4DR4E 1Y60A 1KKHA 2R42A 4OKGA 2F1DA 3T1HE 1Y4SA 1N0VC 4FW9A 3Q1QA 3M6AA 2HKJA 4DR6I 5IT9Q 4QNJA 5DNXA 4FW4A 1XXEA 1FKAE 2PO1B 2GQ0A 4X64E 4B3TE 4OO1E 3B78A 4LF6E 5ELWA 4JI7E 4DV7I 1UDOA 4JV5E 1HR0I 2BA0G 4LF8E 1N32I 1S16A 3K1JA 4MU1A 4RPFA 4JI0E 2CGEA 4OX9I 1IBMI 2JT2A 4AM3A 5A2QC 4JI8I 1USUA 2X36A 2BA1G 2UUAE 4MU4A 4Z7CA 4YHHI 5IT9C 1FI4A 4WUDA 2DEJA 2VESA 2PO0B 3ZM7A 4K0KI 1A6FA 2VF3A 4LFCE 1N34E 4HXZA 2WP8B 1XMQI 1S4EA 3CDJA 3JAMQ 3CWVA 1OJ4A 2UUCE 5DRQA 5BR8E 1Z0VA 1XNRI 4B3RI 4LF5I 4MYUA 4IFDF 3OTOI 4DR3I 5K36E 2UU9E 1I94E 2NN6A 4IFDC 4DV1I 3PS2A 4JI6E 1HNWI 3P3EA 2C39A 4BA2B 4Z7YA 2DEIA 1IBME 4U3DA 1ZXMA 1MG7A 4JI8E 3J7AG 4U3BA 4LOMA 4YY3E 2PO2A 1MX0A 2C38B 1P42A 2O1VA 1UDQA 4JI3I 1USVA 4X62E 1NHHA 1XNQI 5LL6R 4LF7I 1HK7A 1N33E 2BR2B 3J80C 3P76A 2Z5CB 1IBKI 1WUUA 2WNRA 4X66I 2V2VA 2Z5BB 4LCHA 2C37A 4FWGA 4NXMI 2BV3A 4DUZE 3T1YI 4IZJD 3QT8A 1RHYA 4DV1E 3GLLA 4EMDA 5L3JA 1KIJA 1ZM2A 4IZJB 2ZBKB 4BA1B 4X65I 1FJGE 1H73A 4ZVIA 1J5EI 1Z5CA 4GKJI 3H1CA 2JEAA 1ZXNA 4AQYI 1B62A 1QZRA 1N36I 4LFBE 2VQEE 3WU3A 5C0XA 5LMUI 3V5RA 3GONA 4GKKI 2O1UA 1NHJA 2ZM6I 3M7NG 2E5LE 2NN6D 4IFDA 4MU3A 4LCFA 3J81C 4DUYE 4DR1E 3PYGA 2UXBE 3P3GA 3WU4A 4DU8A 2JE6A 4KHPE 4JG4A 4DV3I 3KRNA 3ZZTA 4JI4I 3UHMA 1RR9A 2V34A 3U1KA 5A2QQ 1XMOE 5DROA 4JI5I 2O3ZA 4IS9A 2HFUA 5LMNE 2GS8A 1KVKA 1PVGA 4FWDA 4OO1A 5LMUE 4DV0I 4FW7A 2UXCI 2HKEA 2OI2A 2F4VI 4B3ME 1ELOA 3HJCA 4URLA 2ZITA 4IZKA 2CVEA 5JEAD 1ZM9A 4USMA 2C37B 2PNMA 1KTVA 5JEAB 4DV6E 3U1YA 4LCGA 4N3OA 1UEKA 5C0XF 3ZZUA 3H4LA 2A2CA 5C0XC 4MYTA 3PYDA 1IBLI 3LPSA 5FLXC 4DR6E 1Z5BA 3V2UC 4HACA 2J7KA 2PNZA 5DRPA 2BA0D 5K36A 4DV5I 4MQYA 4DV0E 3Q6NA 2PNLA 4LF9I 3J80Q 3PRYA 4IFDD 4DV7E 1H72C 1H7SA 2JEBA 2BA1D 1N32E 2J65A 1HR0E 1MU5A 1ZM4A 1ZM3A 4JYAI 1N0UA 4JI2I 4OX9E 2O1WA 3L7ZA 3LTOA 2VQFI 2JE6B 4YHHE 4DV4I 3QT7A 4USKA 1YHCA 4K0KE 4OO1F 3GMEA 2V8PA 1XMQE 2NN6E 5IWAI 4OO1C 4DV2I 4I3HA 1IBLE 1XNRE 4B3RE 1K47A 4LF5E 2IOQA 2Z5EA 1RREA 3OTOE 4DR3E 1VI7A 1HNZI 4DR2I 1HNXI 4PU9A 2PO1A 3QT5A 1HNWE 3K17A 2HK2A 3F0NA 4LFAI 3CDIA 3PS3A 2A2DA 2E1RA 3J81Q 2V2QA 4DR5I 2XEXA 1EA6A 2X7IA 4NXNI 1U2RA 1Z0BA 4PRXA 4UTGA 4B3SI 4JI1I 4JI3E 5K36F 4DR4I 5JEAE 1XNQE 4LF7E 4NBQA 5DNLA 5K36C 3T1HI 2PO0A 3ZZ0A 1IBKE 1NHIA 4X66E 2WP8A 4FN5A 4NXME 2NN6B 3T1YE 1D6TA 4WUBA 3ZKDA 4P7AA 4X64I 4B3TI 2HHHI 2C39B 4LF6I 1PIEA 4X65E 4JI7I 4GKJE 1J5EE 4JV5I 4LF8I 4BA2A 4AQYE 2UUBI 2BM1A 2PO2B 4JI0I 1N36E 4IFDE 3M7ND 4UT4A 2UUAI 4GKKE 4AIMA 2C38A 4R1FA 5FLXQ 2ZM6E 4LFCI 1Y5YA 1VISA 2WNRB 1N34I 1BKNA 5GMDA 1FWKA 3P06A 2UUCI 2BR2A 3B8HA 5BR8I 2Z5CA 5EKWA 4MDTA 3DD6A 4DPYA 2Z5BA 4ED4A 2HHHE 4DV3E 2UU9I 4JI4E 4MU0A 1I94I 1Z0TA 4DXLA 5JEAF 4JI6I 4JI5E 1Z0EA 4LPFA 3Q6MA 2IERA 5JEAC 2JEAB 5C0XD 1NZ0A 1FWLA 4IZJA 1Z5AA 2WW4A 2UUBE 4BA1A 3M85G 3HKMA 5C0XB 2CG9A 1UDSA 4PRVA 4YY3I 2UXCE 2F4VE 3GCMA 4WUCA 4LF4I 4P52A 4HY1A 4ISAA 3LNUA 2Q2EB 4X62I 4IFDB 1N33I 4XTJA 3J7AM 4DPWA 3PYFA 3PYEA 1Y4UA 4AIDA 2IESA 2GO4A 4DR7I 1B63A 4DUZI 1Z0WA 1OYPA 2BM0A 3M85D 2CZ9A 1H74A 4FW3A 1OYRA 4OO1D 1E3HA 2UXDI 4M1KA 1FJGI 3K85A 4OO1B 1XHKA 2AJ4A 3JAMC 4DV5E 1Z59A 3WU5A 2GO3A 4DPXA 4DU7A 2LJPA 4LF9E 3QT6A 4DPTA 4QNKA 4LFBI 2VQEI 1OYSA 4LF4E 2AE8A 2IOPA 3NZKA 4IZKB 2O1TA 4JYAE 4JI2E 4FW5A 4J3DA 3B4TA 1Y6ZA 1R6MA 2VQFE 1DARA 4GQUA 1R6LA 2E5LI 2V2ZA 4DV4E 4DR7E 4DUYI 4DR1I 2UXBI 2HFSA 3HULA 5JEAA
chains in the Genus database with same CATH topology
5DRRA 4FW4A 1XXEA 4U3DA 2GO3A 4U3BA 5DRQA 4FW7A 4LCFA 1P42A 3P3CA 2IESA 2GO4A 2IERA 3NZKA 3P3GA 4FW6A 3PS3A 1YHCA 4FW5A 4J3DA 5DRPA 4OKGA 2JT2A 4MQYA 3P76A 4OZEA 3PS2A 3UHMA 4FW3A 4LCHA 3P3EA 5DROA 1YH8A 4MDTA 2J65A 2O3ZA 4IS9A 4LCGA 3U1YA 3PS1A 4ISAA 2VESA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DRR A;  4FW4 A;  1XXE A;  4U3D A;  2GO3 A;  4U3B A;  5DRQ A;  4FW7 A;  4LCF A;  1P42 A;  3P3C A;  2IES A;  2GO4 A;  2IER A;  3NZK A;  3P3G A;  4FW6 A;  3PS3 A;  1YHC A;  4FW5 A;  4J3D A;  5DRP A;  4OKG A;  2JT2 A;  4MQY A;  3P76 A;  4OZE A;  3PS2 A;  3UHM A;  4FW3 A;  4LCH A;  3P3E A;  5DRO A;  1YH8 A;  4MDT A;  2J65 A;  2O3Z A;  4IS9 A;  4LCG A;  3U1Y A;  3PS1 A;  4ISA A;  2VES A; 
#chains in the Genus database with same CATH topology
 5DRR A;  2NPF A;  4DPU A;  4KHP I;  1Z0G A;  5IWA E;  1FNM A;  4HYM A;  3WU6 A;  1H7U A;  4DV2 E;  1EI1 A;  5K36 D;  2EFG A;  1UDN A;  2UXD E;  4HAC B;  3D4J A;  1PKP A;  3B82 A;  2PNZ B;  4FW6 A;  1XMO I;  5FWK A;  5K36 B;  5LMN I;  2R3V A;  1HNZ E;  4DR2 E;  1HNX E;  3ZKB A;  4OZE A;  2JEB B;  2HK3 A;  4KQV A;  5C0X E;  4LFA E;  1YH8 A;  4B3M I;  3PS1 A;  2NN6 F;  4DR5 E;  5EL9 A;  3L7Z B;  4NXN E;  2NN6 C;  4FWH A;  5GME A;  4B3S E;  4JI1 E;  3P3C A;  4DV6 I;  1E3P A;  1Z0C A;  4DR4 E;  1Y60 A;  1KKH A;  2R42 A;  4OKG A;  2F1D A;  3T1H E;  1Y4S A;  1N0V C;  4FW9 A;  3Q1Q A;  3M6A A;  2HKJ A;  4DR6 I;  5IT9 Q;  4QNJ A;  5DNX A;  4FW4 A;  1XXE A;  1FKA E;  2PO1 B;  2GQ0 A;  4X64 E;  4B3T E;  4OO1 E;  3B78 A;  4LF6 E;  5ELW A;  4JI7 E;  4DV7 I;  1UDO A;  4JV5 E;  1HR0 I;  2BA0 G;  4LF8 E;  1N32 I;  1S16 A;  3K1J A;  4MU1 A;  4RPF A;  4JI0 E;  2CGE A;  4OX9 I;  1IBM I;  2JT2 A;  4AM3 A;  5A2Q C;  4JI8 I;  1USU A;  2X36 A;  2BA1 G;  2UUA E;  4MU4 A;  4Z7C A;  4YHH I;  5IT9 C;  1FI4 A;  4WUD A;  2DEJ A;  2VES A;  2PO0 B;  3ZM7 A;  4K0K I;  1A6F A;  2VF3 A;  4LFC E;  1N34 E;  4HXZ A;  2WP8 B;  1XMQ I;  1S4E A;  3CDJ A;  3JAM Q;  3CWV A;  1OJ4 A;  2UUC E;  5DRQ A;  5BR8 E;  1Z0V A;  1XNR I;  4B3R I;  4LF5 I;  4MYU A;  4IFD F;  3OTO I;  4DR3 I;  5K36 E;  2UU9 E;  1I94 E;  2NN6 A;  4IFD C;  4DV1 I;  3PS2 A;  4JI6 E;  1HNW I;  3P3E A;  2C39 A;  4BA2 B;  4Z7Y A;  2DEI A;  1IBM E;  4U3D A;  1ZXM A;  1MG7 A;  4JI8 E;  3J7A G;  4U3B A;  4LOM A;  4YY3 E;  2PO2 A;  1MX0 A;  2C38 B;  1P42 A;  2O1V A;  1UDQ A;  4JI3 I;  1USV A;  4X62 E;  1NHH A;  1XNQ I;  5LL6 R;  4LF7 I;  1HK7 A;  1N33 E;  2BR2 B;  3J80 C;  3P76 A;  2Z5C B;  1IBK I;  1WUU A;  2WNR A;  4X66 I;  2V2V A;  2Z5B B;  4LCH A;  2C37 A;  4FWG A;  4NXM I;  2BV3 A;  4DUZ E;  3T1Y I;  4IZJ D;  3QT8 A;  1RHY A;  4DV1 E;  3GLL A;  4EMD A;  5L3J A;  1KIJ A;  1ZM2 A;  4IZJ B;  2ZBK B;  4BA1 B;  4X65 I;  1FJG E;  1H73 A;  4ZVI A;  1J5E I;  1Z5C A;  4GKJ I;  3H1C A;  2JEA A;  1ZXN A;  4AQY I;  1B62 A;  1QZR A;  1N36 I;  4LFB E;  2VQE E;  3WU3 A;  5C0X A;  5LMU I;  3V5R A;  3GON A;  4GKK I;  2O1U A;  1NHJ A;  2ZM6 I;  3M7N G;  2E5L E;  2NN6 D;  4IFD A;  4MU3 A;  4LCF A;  3J81 C;  4DUY E;  4DR1 E;  3PYG A;  2UXB E;  3P3G A;  3WU4 A;  4DU8 A;  2JE6 A;  4KHP E;  4JG4 A;  4DV3 I;  3KRN A;  3ZZT A;  4JI4 I;  3UHM A;  1RR9 A;  2V34 A;  3U1K A;  5A2Q Q;  1XMO E;  5DRO A;  4JI5 I;  2O3Z A;  4IS9 A;  2HFU A;  5LMN E;  2GS8 A;  1KVK A;  1PVG A;  4FWD A;  4OO1 A;  5LMU E;  4DV0 I;  4FW7 A;  2UXC I;  2HKE A;  2OI2 A;  2F4V I;  4B3M E;  1ELO A;  3HJC A;  4URL A;  2ZIT A;  4IZK A;  2CVE A;  5JEA D;  1ZM9 A;  4USM A;  2C37 B;  2PNM A;  1KTV A;  5JEA B;  4DV6 E;  3U1Y A;  4LCG A;  4N3O A;  1UEK A;  5C0X F;  3ZZU A;  3H4L A;  2A2C A;  5C0X C;  4MYT A;  3PYD A;  1IBL I;  3LPS A;  5FLX C;  4DR6 E;  1Z5B A;  3V2U C;  4HAC A;  2J7K A;  2PNZ A;  5DRP A;  2BA0 D;  5K36 A;  4DV5 I;  4MQY A;  4DV0 E;  3Q6N A;  2PNL A;  4LF9 I;  3J80 Q;  3PRY A;  4IFD D;  4DV7 E;  1H72 C;  1H7S A;  2JEB A;  2BA1 D;  1N32 E;  2J65 A;  1HR0 E;  1MU5 A;  1ZM4 A;  1ZM3 A;  4JYA I;  1N0U A;  4JI2 I;  4OX9 E;  2O1W A;  3L7Z A;  3LTO A;  2VQF I;  2JE6 B;  4YHH E;  4DV4 I;  3QT7 A;  4USK A;  1YHC A;  4K0K E;  4OO1 F;  3GME A;  2V8P A;  1XMQ E;  2NN6 E;  5IWA I;  4OO1 C;  4DV2 I;  4I3H A;  1IBL E;  1XNR E;  4B3R E;  1K47 A;  4LF5 E;  2IOQ A;  2Z5E A;  1RRE A;  3OTO E;  4DR3 E;  1VI7 A;  1HNZ I;  4DR2 I;  1HNX I;  4PU9 A;  2PO1 A;  3QT5 A;  1HNW E;  3K17 A;  2HK2 A;  3F0N A;  4LFA I;  3CDI A;  3PS3 A;  2A2D A;  2E1R A;  3J81 Q;  2V2Q A;  4DR5 I;  2XEX A;  1EA6 A;  2X7I A;  4NXN I;  1U2R A;  1Z0B A;  4PRX A;  4UTG A;  4B3S I;  4JI1 I;  4JI3 E;  5K36 F;  4DR4 I;  5JEA E;  1XNQ E;  4LF7 E;  4NBQ A;  5DNL A;  5K36 C;  3T1H I;  2PO0 A;  3ZZ0 A;  1IBK E;  1NHI A;  4X66 E;  2WP8 A;  4FN5 A;  4NXM E;  2NN6 B;  3T1Y E;  1D6T A;  4WUB A;  3ZKD A;  4P7A A;  4X64 I;  4B3T I;  2HHH I;  2C39 B;  4LF6 I;  1PIE A;  4X65 E;  4JI7 I;  4GKJ E;  1J5E E;  4JV5 I;  4LF8 I;  4BA2 A;  4AQY E;  2UUB I;  2BM1 A;  2PO2 B;  4JI0 I;  1N36 E;  4IFD E;  3M7N D;  4UT4 A;  2UUA I;  4GKK E;  4AIM A;  2C38 A;  4R1F A;  5FLX Q;  2ZM6 E;  4LFC I;  1Y5Y A;  1VIS A;  2WNR B;  1N34 I;  1BKN A;  5GMD A;  1FWK A;  3P06 A;  2UUC I;  2BR2 A;  3B8H A;  5BR8 I;  2Z5C A;  5EKW A;  4MDT A;  3DD6 A;  4DPY A;  2Z5B A;  4ED4 A;  2HHH E;  4DV3 E;  2UU9 I;  4JI4 E;  4MU0 A;  1I94 I;  1Z0T A;  4DXL A;  5JEA F;  4JI6 I;  4JI5 E;  1Z0E A;  4LPF A;  3Q6M A;  2IER A;  5JEA C;  2JEA B;  5C0X D;  1NZ0 A;  1FWL A;  4IZJ A;  1Z5A A;  2WW4 A;  2UUB E;  4BA1 A;  3M85 G;  3HKM A;  5C0X B;  2CG9 A;  1UDS A;  4PRV A;  4YY3 I;  2UXC E;  2F4V E;  3GCM A;  4WUC A;  4LF4 I;  4P52 A;  4HY1 A;  4ISA A;  3LNU A;  2Q2E B;  4X62 I;  4IFD B;  1N33 I;  4XTJ A;  3J7A M;  4DPW A;  3PYF A;  3PYE A;  1Y4U A;  4AID A;  2IES A;  2GO4 A;  4DR7 I;  1B63 A;  4DUZ I;  1Z0W A;  1OYP A;  2BM0 A;  3M85 D;  2CZ9 A;  1H74 A;  4FW3 A;  1OYR A;  4OO1 D;  1E3H A;  2UXD I;  4M1K A;  1FJG I;  3K85 A;  4OO1 B;  1XHK A;  2AJ4 A;  3JAM C;  4DV5 E;  1Z59 A;  3WU5 A;  2GO3 A;  4DPX A;  4DU7 A;  2LJP A;  4LF9 E;  3QT6 A;  4DPT A;  4QNK A;  4LFB I;  2VQE I;  1OYS A;  4LF4 E;  2AE8 A;  2IOP A;  3NZK A;  4IZK B;  2O1T A;  4JYA E;  4JI2 E;  4FW5 A;  4J3D A;  3B4T A;  1Y6Z A;  1R6M A;  2VQF E;  1DAR A;  4GQU A;  1R6L A;  2E5L I;  2V2Z A;  4DV4 E;  4DR7 E;  4DUY I;  4DR1 I;  2UXB I;  2HFS A;  3HUL A;  5JEA A; 
#chains in the Genus database with same CATH homology
 5DRR A;  4FW4 A;  1XXE A;  4U3D A;  2GO3 A;  4U3B A;  5DRQ A;  4FW7 A;  4LCF A;  1P42 A;  3P3C A;  2IES A;  2GO4 A;  2IER A;  3NZK A;  3P3G A;  4FW6 A;  3PS3 A;  1YHC A;  4FW5 A;  4J3D A;  5DRP A;  4OKG A;  2JT2 A;  4MQY A;  3P76 A;  4OZE A;  3PS2 A;  3UHM A;  4FW3 A;  4LCH A;  3P3E A;  5DRO A;  1YH8 A;  4MDT A;  2J65 A;  2O3Z A;  4IS9 A;  4LCG A;  3U1Y A;  3PS1 A;  4ISA A;  2VES A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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