1RHYA

Crystal structure of imidazole glycerol phosphate dehydratase
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
186
structure length
180
Chain Sequence
SERIASVERTTSETHISCTIDLDHIPGVTEQKINVSTGIGFLDHMFTALAKHGGMSLQLQCKGDLTAEDCALALGEAFKKALGERKGIKRYGYAYAPLDESLSRAVIDISSRPYFMCHLPFTREKVGDLSTEMVSHLLQSFAFAAGVTLHIDSIRGENNHHIAESAFKALALAIRMAISR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of imidazole glycerol-phosphate dehydratase: duplication of an unusual fold
pubmed doi rcsb
molecule tags Lyase
source organism Filobasidiella neoformans
molecule keywords Imidazole glycerol phosphate dehydratase
total genus 55
structure length 180
sequence length 186
chains with identical sequence B
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2003-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 1rhyA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 1rhyA02
5EKWA 2AE8A 2F1DA 4QNJA 4GQUA 4MU4A 4MU1A 1RHYA 4QNKA 5DNLA 5EL9A 5ELWA 5DNXA 4MU3A 4MU0A 4LPFA 4LOMA
chains in the Genus database with same CATH superfamily
4ED4A 4B3RE 2NPFA 1Y4SA 2A2DA 4ZVIA 2R3VA 4MDTA 5C0XE 4BA2B 4NXNI 2ZM6I 3ZZTA 4DU8A 1Y60A 4FN5A 4BA1B 4IS9A 4DV4I 4HXZA 1OYPA 2UXCI 3U1KA 2JEBA 5C0XA 3B82A 3P76A 1RHYA 4NXNE 5L3JA 2ZM6E 3GONA 1Y6ZA 1YH8A 4DV4E 2C37A 3M85G 4WUDA 5A2QQ 4DPYA 3M6AA 2Q2EB 3H1CA 4JG4A 3M85D 1A6FA 4N3OA 3HKMA 2JT2A 4DV7I 2BR2A 1DARA 1Z0BA 4FWDA 3K1JA 4R1FA 1BKNA 4NBQA 2PO1A 4KHPI 2CG9A 1P42A 3LPSA 4DV7E 1UDNA 3ZM7A 1FNMA 2NN6C 4GQUA 1EI1A 3OTOI 4JI3I 2NN6B 4KHPE 2EFGA 2BM1A 4DU7A 2WNRA 1ELOA 2VQFI 2GQ0A 4DV2E 4OX9I 2UXBI 3WU6A 2IERA 4DV1I 4YY3I 4LFAE 2F1DA 3OTOE 4JI3E 1Z5CA 2F4VE 2V34A 4OX9E 2VQFE 1Z0VA 3LTOA 2Z5CB 3PS3A 2UXBE 1U2RA 4BA2A 4LF6I 4YY3E 4GKKI 2O1TA 3HJCA 4BA1A 3DD6A 3H4LA 2CGEA 2ZITA 3V2UC 4IZJD 1E3HA 5K36C 1XNRI 4LF6E 4GKKE 4FW4A 5K36B 4MQYA 2JE6B 3NZKA 1H7SA 2IOPA 4LCGA 3K85A 4LF9I 1XNRE 5JEAC 5DROA 2JEAB 2UXDI 2V2VA 2VESA 4MU4A 5JEAB 1KKHA 3ZZUA 4LF9E 4IFDB 2UXDE 4DV0I 2NN6E 1UEKA 2X7IA 3QT6A 3QT5A 4RPFA 1H7UA 4DXLA 2UU9I 3KRNA 4LCHA 4B3TI 1HNWI 2NN6A 2VF3A 5BR8I 4DR5I 4GKJE 4DPUA 2UU9E 1Z0GA 4UT4A 4LF5I 4DR3I 1HNXI 1HNWE 1ZM3A 1B63A 5BR8E 4OO1F 4P52A 1UDSA 2Z5CA 4DR5E 4X64I 4LF5E 4DR3E 5K36E 1HNXE 1Y5YA 4DV5E 2BM0A 4M1KA 3GCMA 2CZ9A 4DV6E 4X64E 5IWAI 5K36A 3K17A 2DEIA 4OO1D 2JE6A 1USVA 4MYTA 5JEAE 2C38B 4USKA 3QT8A 4HY1A 1RR9A 4IZKB 5IWAE 3L7ZB 2JEAA 3B8HA 3JAMC 5JEAA 4X66I 4ISAA 5IT9Q 4DR4I 4IFDA 4DPTA 1Z5BA 3T1YI 4JI6I 4FW7A 3WU5A 3ZZ0A 3V5RA 1FWLA 1XNQI 4X66E 1KTVA 4LF7E 4I3HA 4DR4E 1Z0TA 4DR6I 3T1YE 4JI6E 4DV2I 4LFCI 5GMEA 2UUBI 2Z5BB 1XNQE 4B3MI 4LFAI 3CDIA 1XXEA 4DR6E 2F4VI 4LFCE 4Z7CA 2UUBE 3D4JA 4AIDA 1ZM9A 5K36F 1N32I 4B3ME 1FKAE 4DUYI 5C0XF 1Z5AA 3F0NA 4FWGA 4PRVA 4DR1E 2J65A 1N33I 4NXME 1Z0WA 2GS8A 1QZRA 1N0VC 2HK3A 1XMOE 1PIEA 1R6MA 2WP8B 1N32E 4DUYE 4U3BA 5JEAF 1ZM4A 4FW5A 5LMNI 1IBME 3JAMQ 1N33E 1OJ4A 2V2ZA 2V8PA 1NZ0A 2C38A 2Z5EA 4HACB 4LPFA 5K36D 3Q6NA 1KVKA 5DNLA 5C0XD 1IBLI 4IZKA 5LMNE 4JYAI 2XEXA 3L7ZA 4LOMA 3WU4A 4X62I 5ELWA 4JI0I 1K47A 4LF4I 5JEAD 1IBLE 1S4EA 1PKPA 4JI7I 2HFUA 4JYAE 3T1HI 5DRQA 5DNXA 4IFDC 1R6LA 4X62E 3GLLA 4JI0E 1Z59A 3GMEA 4LF4E 3U1YA 4WUCA 4IZJB 4X65E 4JI7E 3T1HE 2PO0B 4GKJI 2Z5BA 4XTJA 4EMDA 2BA0D 5IT9C 4JI8E 1J5EI 4K0KE 2A2CA 2AJ4A 3J80C 3CWVA 1UDOA 5LMUI 2O3ZA 1IBKI 4DR7I 2HHHI 1J5EE 1N34E 1E3PA 4KQVA 5DRPA 5FWKA 1VI7A 5EKWA 4DV5I 4JI1E 5LMUE 4URLA 1IBKE 4DR7E 2PO2B 2WP8A 2HHHE 2GO4A 4QNJA 4DV6I 1NHJA 2IESA 4JI2I 4LFBI 4HACA 1H73A 4FW3A 2UUCE 4FW6A 4FW9A 2PNZB 5GMDA 1MX0A 4JI2E 1NHHA 1S16A 2X36A 3HULA 1HNZI 2VQEI 4LFBE 1EA6A 1Y4UA 2HK2A 3PS1A 3PS2A 3ZKDA 1PVGA 4IFDE 2O1WA 1H72C 2PNMA 4DR2E 2WW4A 1XMQI 1I94I 1HNZE 2VQEE 4P7AA 2NN6F 4LF7I 4MU3A 3J81C 3QT7A 3B78A 2GO3A 4DUZI 4IZJA 1YHCA 3WU3A 2BV3A 3J80Q 4Z7YA 1XMQE 4OO1C 2PO0A 1I94E 3CDJA 4LF8I 1FJGI 2E5LI 1USUA 2UUAI 4OO1B 1WUUA 1Z0EA 3B4TA 4J3DA 4DUZE 1B62A 4JI5I 2UXCE 3UHMA 3P06A 4LF8E 2NN6D 1FJGE 2C39B 2E1RA 2E5LE 2UUAE 3J7AM 4DR1I 4OKGA 4DV3I 4MYUA 5EL9A 4B3SI 2O1UA 4NXMI 4JI5E 1XMOI 5DRRA 1OYRA 3P3GA 2PO2A 4YHHI 2OI2A 2J7KA 4DV3E 1HR0I 2ZBKB 1IBMI 4B3SE 4FWHA 2LJPA 2V2QA 1H74A 3M7NG 4YHHE 1HR0E 1RREA 4PU9A 1ZXMA 2PNZA 3P3EA 4IFDF 4AIMA 3M7ND 3J81Q 5LL6R 2BA1G 2DEJA 4JV5I 1HK7A 4MU1A 3PYGA 4AM3A 1UDQA 2CVEA 2BA1D 1D6TA 1ZXNA 4QNKA 4X65I 4DV1E 4WUBA 3PYFA 4AQYI 4OO1E 4JV5E 1FWKA 5FLXC 4IFDD 2R42A 4DPXA 4DPWA 1MU5A 1VISA 3LNUA 1N0UA 2IOQA 2PNLA 3J7AG 3PYDA 4JI8I 4USMA 2BA0G 4OO1A 4AQYE 5C0XC 4K0KI 1OYSA 3P3CA 2JEBB 5C0XB 4HYMA 2AE8A 2C39A 2HKEA 1N34I 1XHKA 2C37B 1Z0CA 4JI1I 4LCFA 3Q1QA 4JI4I 1N36I 1NHIA 5A2QC 2BR2B 1MG7A 2HFSA 1KIJA 2UUCI 4OZEA 3PYEA 2PO1B 4JI4E 1N36E 1FI4A 3ZKBA 4DV0E 3Q6MA 4B3RI 2HKJA 4PRXA 4U3DA 3PRYA 4B3TE 4DR2I 5FLXQ 4UTGA 1ZM2A 2WNRB 2O1VA 4MU0A
chains in the Genus database with same CATH topology
5EKWA 2AE8A 2F1DA 4QNJA 4GQUA 4MU4A 4MU1A 1RHYA 4QNKA 5DNLA 5EL9A 5ELWA 5DNXA 4MU3A 4MU0A 4LPFA 4LOMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EKW A;  2AE8 A;  2F1D A;  4QNJ A;  4GQU A;  4MU4 A;  4MU1 A;  1RHY A;  4QNK A;  5DNL A;  5EL9 A;  5ELW A;  5DNX A;  4MU3 A;  4MU0 A;  4LPF A;  4LOM A; 
#chains in the Genus database with same CATH topology
 4ED4 A;  4B3R E;  2NPF A;  1Y4S A;  2A2D A;  4ZVI A;  2R3V A;  4MDT A;  5C0X E;  4BA2 B;  4NXN I;  2ZM6 I;  3ZZT A;  4DU8 A;  1Y60 A;  4FN5 A;  4BA1 B;  4IS9 A;  4DV4 I;  4HXZ A;  1OYP A;  2UXC I;  3U1K A;  2JEB A;  5C0X A;  3B82 A;  3P76 A;  1RHY A;  4NXN E;  5L3J A;  2ZM6 E;  3GON A;  1Y6Z A;  1YH8 A;  4DV4 E;  2C37 A;  3M85 G;  4WUD A;  5A2Q Q;  4DPY A;  3M6A A;  2Q2E B;  3H1C A;  4JG4 A;  3M85 D;  1A6F A;  4N3O A;  3HKM A;  2JT2 A;  4DV7 I;  2BR2 A;  1DAR A;  1Z0B A;  4FWD A;  3K1J A;  4R1F A;  1BKN A;  4NBQ A;  2PO1 A;  4KHP I;  2CG9 A;  1P42 A;  3LPS A;  4DV7 E;  1UDN A;  3ZM7 A;  1FNM A;  2NN6 C;  4GQU A;  1EI1 A;  3OTO I;  4JI3 I;  2NN6 B;  4KHP E;  2EFG A;  2BM1 A;  4DU7 A;  2WNR A;  1ELO A;  2VQF I;  2GQ0 A;  4DV2 E;  4OX9 I;  2UXB I;  3WU6 A;  2IER A;  4DV1 I;  4YY3 I;  4LFA E;  2F1D A;  3OTO E;  4JI3 E;  1Z5C A;  2F4V E;  2V34 A;  4OX9 E;  2VQF E;  1Z0V A;  3LTO A;  2Z5C B;  3PS3 A;  2UXB E;  1U2R A;  4BA2 A;  4LF6 I;  4YY3 E;  4GKK I;  2O1T A;  3HJC A;  4BA1 A;  3DD6 A;  3H4L A;  2CGE A;  2ZIT A;  3V2U C;  4IZJ D;  1E3H A;  5K36 C;  1XNR I;  4LF6 E;  4GKK E;  4FW4 A;  5K36 B;  4MQY A;  2JE6 B;  3NZK A;  1H7S A;  2IOP A;  4LCG A;  3K85 A;  4LF9 I;  1XNR E;  5JEA C;  5DRO A;  2JEA B;  2UXD I;  2V2V A;  2VES A;  4MU4 A;  5JEA B;  1KKH A;  3ZZU A;  4LF9 E;  4IFD B;  2UXD E;  4DV0 I;  2NN6 E;  1UEK A;  2X7I A;  3QT6 A;  3QT5 A;  4RPF A;  1H7U A;  4DXL A;  2UU9 I;  3KRN A;  4LCH A;  4B3T I;  1HNW I;  2NN6 A;  2VF3 A;  5BR8 I;  4DR5 I;  4GKJ E;  4DPU A;  2UU9 E;  1Z0G A;  4UT4 A;  4LF5 I;  4DR3 I;  1HNX I;  1HNW E;  1ZM3 A;  1B63 A;  5BR8 E;  4OO1 F;  4P52 A;  1UDS A;  2Z5C A;  4DR5 E;  4X64 I;  4LF5 E;  4DR3 E;  5K36 E;  1HNX E;  1Y5Y A;  4DV5 E;  2BM0 A;  4M1K A;  3GCM A;  2CZ9 A;  4DV6 E;  4X64 E;  5IWA I;  5K36 A;  3K17 A;  2DEI A;  4OO1 D;  2JE6 A;  1USV A;  4MYT A;  5JEA E;  2C38 B;  4USK A;  3QT8 A;  4HY1 A;  1RR9 A;  4IZK B;  5IWA E;  3L7Z B;  2JEA A;  3B8H A;  3JAM C;  5JEA A;  4X66 I;  4ISA A;  5IT9 Q;  4DR4 I;  4IFD A;  4DPT A;  1Z5B A;  3T1Y I;  4JI6 I;  4FW7 A;  3WU5 A;  3ZZ0 A;  3V5R A;  1FWL A;  1XNQ I;  4X66 E;  1KTV A;  4LF7 E;  4I3H A;  4DR4 E;  1Z0T A;  4DR6 I;  3T1Y E;  4JI6 E;  4DV2 I;  4LFC I;  5GME A;  2UUB I;  2Z5B B;  1XNQ E;  4B3M I;  4LFA I;  3CDI A;  1XXE A;  4DR6 E;  2F4V I;  4LFC E;  4Z7C A;  2UUB E;  3D4J A;  4AID A;  1ZM9 A;  5K36 F;  1N32 I;  4B3M E;  1FKA E;  4DUY I;  5C0X F;  1Z5A A;  3F0N A;  4FWG A;  4PRV A;  4DR1 E;  2J65 A;  1N33 I;  4NXM E;  1Z0W A;  2GS8 A;  1QZR A;  1N0V C;  2HK3 A;  1XMO E;  1PIE A;  1R6M A;  2WP8 B;  1N32 E;  4DUY E;  4U3B A;  5JEA F;  1ZM4 A;  4FW5 A;  5LMN I;  1IBM E;  3JAM Q;  1N33 E;  1OJ4 A;  2V2Z A;  2V8P A;  1NZ0 A;  2C38 A;  2Z5E A;  4HAC B;  4LPF A;  5K36 D;  3Q6N A;  1KVK A;  5DNL A;  5C0X D;  1IBL I;  4IZK A;  5LMN E;  4JYA I;  2XEX A;  3L7Z A;  4LOM A;  3WU4 A;  4X62 I;  5ELW A;  4JI0 I;  1K47 A;  4LF4 I;  5JEA D;  1IBL E;  1S4E A;  1PKP A;  4JI7 I;  2HFU A;  4JYA E;  3T1H I;  5DRQ A;  5DNX A;  4IFD C;  1R6L A;  4X62 E;  3GLL A;  4JI0 E;  1Z59 A;  3GME A;  4LF4 E;  3U1Y A;  4WUC A;  4IZJ B;  4X65 E;  4JI7 E;  3T1H E;  2PO0 B;  4GKJ I;  2Z5B A;  4XTJ A;  4EMD A;  2BA0 D;  5IT9 C;  4JI8 E;  1J5E I;  4K0K E;  2A2C A;  2AJ4 A;  3J80 C;  3CWV A;  1UDO A;  5LMU I;  2O3Z A;  1IBK I;  4DR7 I;  2HHH I;  1J5E E;  1N34 E;  1E3P A;  4KQV A;  5DRP A;  5FWK A;  1VI7 A;  5EKW A;  4DV5 I;  4JI1 E;  5LMU E;  4URL A;  1IBK E;  4DR7 E;  2PO2 B;  2WP8 A;  2HHH E;  2GO4 A;  4QNJ A;  4DV6 I;  1NHJ A;  2IES A;  4JI2 I;  4LFB I;  4HAC A;  1H73 A;  4FW3 A;  2UUC E;  4FW6 A;  4FW9 A;  2PNZ B;  5GMD A;  1MX0 A;  4JI2 E;  1NHH A;  1S16 A;  2X36 A;  3HUL A;  1HNZ I;  2VQE I;  4LFB E;  1EA6 A;  1Y4U A;  2HK2 A;  3PS1 A;  3PS2 A;  3ZKD A;  1PVG A;  4IFD E;  2O1W A;  1H72 C;  2PNM A;  4DR2 E;  2WW4 A;  1XMQ I;  1I94 I;  1HNZ E;  2VQE E;  4P7A A;  2NN6 F;  4LF7 I;  4MU3 A;  3J81 C;  3QT7 A;  3B78 A;  2GO3 A;  4DUZ I;  4IZJ A;  1YHC A;  3WU3 A;  2BV3 A;  3J80 Q;  4Z7Y A;  1XMQ E;  4OO1 C;  2PO0 A;  1I94 E;  3CDJ A;  4LF8 I;  1FJG I;  2E5L I;  1USU A;  2UUA I;  4OO1 B;  1WUU A;  1Z0E A;  3B4T A;  4J3D A;  4DUZ E;  1B62 A;  4JI5 I;  2UXC E;  3UHM A;  3P06 A;  4LF8 E;  2NN6 D;  1FJG E;  2C39 B;  2E1R A;  2E5L E;  2UUA E;  3J7A M;  4DR1 I;  4OKG A;  4DV3 I;  4MYU A;  5EL9 A;  4B3S I;  2O1U A;  4NXM I;  4JI5 E;  1XMO I;  5DRR A;  1OYR A;  3P3G A;  2PO2 A;  4YHH I;  2OI2 A;  2J7K A;  4DV3 E;  1HR0 I;  2ZBK B;  1IBM I;  4B3S E;  4FWH A;  2LJP A;  2V2Q A;  1H74 A;  3M7N G;  4YHH E;  1HR0 E;  1RRE A;  4PU9 A;  1ZXM A;  2PNZ A;  3P3E A;  4IFD F;  4AIM A;  3M7N D;  3J81 Q;  5LL6 R;  2BA1 G;  2DEJ A;  4JV5 I;  1HK7 A;  4MU1 A;  3PYG A;  4AM3 A;  1UDQ A;  2CVE A;  2BA1 D;  1D6T A;  1ZXN A;  4QNK A;  4X65 I;  4DV1 E;  4WUB A;  3PYF A;  4AQY I;  4OO1 E;  4JV5 E;  1FWK A;  5FLX C;  4IFD D;  2R42 A;  4DPX A;  4DPW A;  1MU5 A;  1VIS A;  3LNU A;  1N0U A;  2IOQ A;  2PNL A;  3J7A G;  3PYD A;  4JI8 I;  4USM A;  2BA0 G;  4OO1 A;  4AQY E;  5C0X C;  4K0K I;  1OYS A;  3P3C A;  2JEB B;  5C0X B;  4HYM A;  2AE8 A;  2C39 A;  2HKE A;  1N34 I;  1XHK A;  2C37 B;  1Z0C A;  4JI1 I;  4LCF A;  3Q1Q A;  4JI4 I;  1N36 I;  1NHI A;  5A2Q C;  2BR2 B;  1MG7 A;  2HFS A;  1KIJ A;  2UUC I;  4OZE A;  3PYE A;  2PO1 B;  4JI4 E;  1N36 E;  1FI4 A;  3ZKB A;  4DV0 E;  3Q6M A;  4B3R I;  2HKJ A;  4PRX A;  4U3D A;  3PRY A;  4B3T E;  4DR2 I;  5FLX Q;  4UTG A;  1ZM2 A;  2WNR B;  2O1V A;  4MU0 A; 
#chains in the Genus database with same CATH homology
 5EKW A;  2AE8 A;  2F1D A;  4QNJ A;  4GQU A;  4MU4 A;  4MU1 A;  1RHY A;  4QNK A;  5DNL A;  5EL9 A;  5ELW A;  5DNX A;  4MU3 A;  4MU0 A;  4LPF A;  4LOM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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