1Y5YA

Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (fae) from methylobacterium extorquens am1
Total Genus 55

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
159
structure length
159
Chain Sequence
AKITKVQVGEALVGDGNEVAHIDLIIGPRGSPAETAFCNGLVNNKHGFTSLLAVIAPNLPCKPNTLMFNKVTINDARQAVQMFGPAQHGVAMAVQDAVAEGIIPADEADDLYVLVGVFIHWEAADDAKIQKYNYEATKLSIQRAVNGEPKASVVTEQRK

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
EMPTYTVIII1 (102-105)TI2 (105-108)S2 (21-29)AH3 (127-147)S1 (8-14)TI1 (17-20)TII'1 (16-19)TI6 (121-124)TII1 (29-32)TI3 (106-109)TI4 (108-111)AH1 (33-43)S7 (112-119)TII2 (46-49)TIV3 (70-73)S3 (51-53)S6 (66-70)S5 (60-61)TIV2 (62-65)AH2 (77-101)AH4 (152-157)S4 (55-57)TII3 (57-60)TIV4 (148-151)Updating...
connected with : NaN
molecule tags Lyase
source organism Methylobacterium extorquens
publication title How an enzyme binds the C1-carrier tetrahydromethanopterin: Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1
pubmed doi rcsb
molecule keywords Formaldehyde-activating enzyme fae
total genus 55
structure length 159
sequence length 159
chains with identical sequence B, C, D, E
ec nomenclature ec 4.2.1.147: 5,6,7,8-tetrahydromethanopterin hydro-lyase.
pdb deposition date 2004-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08714 Fae Formaldehyde-activating enzyme (Fae)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.60 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Formaldehyde-activating enzyme 1y5yA00
1Y5YA 1Y60A
chains in the Genus database with same CATH superfamily
2NN6C 4DV0E 4NXMI 4PU9A 4JI7E 5LMNE 5LMUE 4AM3A 2UU9E 2UXCE 1VISA 2CVEA 4JI3I 4DPYA 4B3SE 1N33E 2C37B 2PO0B 1N0UA 1ZM2A 1HNWI 1QZRA 1IBKI 2UXDI 5DRPA 4X66I 1FNMA 3CDJA 1WUUA 5GMEA 1H72C 4DV3I 2NPFA 2CZ9A 4DPUA 4BA2B 1B62A 3OTOI 4IFDB 4DV0I 5DRQA 4JI6I 5K36E 4JYAI 2E1RA 1XMQE 5LMNI 3NZKA 2UU9I 2UXCI 1D6TA 4RPFA 4DU7A 4LPFA 2A2DA 3H4LA 1USUA 2JT2A 3GLLA 4HACA 2WNRB 2IESA 3WU6A 2E5LE 4DR5E 4X62E 3P3GA 3HULA 4X64E 2UXBI 3M7ND 1IBLE 2CGEA 4DV5E 1NZ0A 1Z0EA 2Z5BB 5A2QC 3T1HE 4DUZE 3ZZTA 1ZM4A 2BR2A 3P06A 3Q6MA 2HK2A 4LFCE 3J80Q 5C0XB 1PIEA 1Y5YA 5GMDA 2PNZB 3LPSA 4LOMA 4JI4E 4IFDD 4B3RE 1NHJA 1K47A 1ZXMA 2E5LI 4OO1C 4DR5I 2C37A 2PO0A 4BA1B 1XMOE 4X62I 4JG4A 5DNLA 4NBQA 4X64I 4LF5E 1ZM3A 1IBLI 3T1YI 4DV5I 3CDIA 3T1HI 4DUZI 5IT9C 3QT8A 3M85D 4IS9A 1FWLA 2C39B 3PRYA 4DV2E 4GKKE 4LFCI 2F1DA 2HFSA 4IFDA 2Z5EA 4GQUA 3LTOA 4KQVA 1IBME 4I3HA 5IT9Q 4JV5E 2BV3A 4FW6A 5C0XD 4DV4E 3LNUA 1XMOI 1UEKA 2WNRA 4LF5I 4WUCA 1RREA 3PS2A 3DD6A 2WP8B 4HYMA 4PRVA 1KTVA 3HKMA 4DR3E 4OKGA 2X7IA 1FI4A 4N3OA 4FN5A 4DR4E 4QNKA 5DNXA 2Z5BA 4UTGA 1H7UA 5K36B 1N36E 4DV2I 4GKKI 5JEAC 2JEBA 1Z0BA 1ZXNA 2GO3A 4LF4E 4DR6E 1HK7A 4LF7E 1KIJA 1IBMI 5C0XA 2ZBKB 3ZZ0A 4JV5I 4K0KE 4IFDF 4P52A 1HNXE 1OJ4A 1RHYA 1I94E 4DR7I 2C38B 2NN6B 3B8HA 3ZM7A 4DUYE 2PNMA 4FW5A 4LFAE 4PRXA 4OX9E 4DR3I 1N34E 3P3EA 2VQFE 4URLA 4U3BA 1Z0VA 4DR4I 1N36I 4B3ME 3M6AA 1XHKA 2WW4A 2BA1G 4LF4I 1N32I 4DR6I 4MDTA 2VQEE 2O3ZA 1UDSA 4LF7I 5K36D 2Q2EB 5FLXC 4JI7I 5LMUI 4UT4A 2HHHE 2JE6B 1A6FA 4K0KI 4IZKB 1HNXI 1MG7A 4B3SI 3H1CA 5C0XF 1YHCA 1N33I 3CWVA 3PYGA 2IERA 4DU8A 5FLXQ 4J3DA 2ZM6E 4JI0E 2WP8A 3PYFA 2VQFI 2V8PA 2NN6D 3B4TA 5EL9A 2NN6E 4LCHA 3ZKBA 1OYRA 1RR9A 1S16A 2HK3A 4B3MI 4YHHE 3P3CA 5K36A 4DV6E 5DROA 1HR0E 2VQEI 4HY1A 1Z0WA 1FKAE 4AIMA 1XMQI 3GCMA 3J7AM 4DV7E 2HHHI 4LF8E 4MU4A 2BM1A 5L3JA 5A2QQ 1ZM9A 2O1VA 4DPWA 4B3TE 2PO1B 1H74A 1B63A 4DR1E 4JI1E 3GMEA 2AE8A 2CG9A 4JI0I 1MX0A 1USVA 2HKEA 3WU5A 4FWGA 4JI8E 3UHMA 2Z5CB 3PS1A 1XNQE 4YHHI 4OO1B 1Z0TA 2VF3A 3D4JA 2IOQA 4MQYA 4AIDA 3ZZUA 1HR0I 1UDNA 1Z5BA 1BKNA 4BA2A 3J7AG 5FWKA 5K36F 4DV7I 2VESA 2HKJA 4LF8I 4WUBA 2PNLA 1YH8A 1FJGE 4JI4I 1R6LA 2UUCE 4B3TI 4IZKA 4B3RI 1EI1A 4DR1I 2R42A 5IWAE 4JI1I 4MU0A 2IOPA 4LFBE 3Q6NA 4MYUA 1XNQI 3ZKDA 2NN6F 2BA0D 2GS8A 5EKWA 3L7ZB 3U1YA 2O1TA 4OO1D 4JI5E 4HACB 4OO1E 1PKPA 2BA0G 4USKA 4JI2E 3F0NA 2UUCI 5JEAB 2PNZA 1Z59A 1ELOA 4YY3E 5IWAI 2PO1A 1OYPA 4DV4I 4LFBI 2BA1D 4BA1A 4DPXA 4WUDA 2XEXA 1OYSA 4JI6E 4USMA 4R1FA 4JYAE 4KHPE 4Z7CA 2DEJA 1HNZE 1UDOA 1UDQA 2C39A 4LCGA 4JI5I 2UUAE 4LF6E 1XNRE 3Q1QA 1Y6ZA 3PS3A 1Y60A 4JI2I 1H73A 3GONA 1H7SA 4FWDA 4YY3I 3QT6A 2UXBE 1KVKA 3QT5A 4DR2E 1I94I 4DUYI 4LFAI 3KRNA 4IFDC 5JEAD 3B78A 5JEAE 4OX9I 1N34I 2JEAB 2ZITA 1Z5AA 5DRRA 1S4EA 3B82A 3V5RA 2F4VE 4KHPI 1R6MA 1HNZI 1Z0GA 2X36A 3L7ZA 1DARA 2UUAI 4LF6I 1XNRI 3PYEA 2O1UA 4DV1E 4OO1F 5BR8E 1Y4UA 1KKHA 2J65A 2A2CA 5JEAA 3WU3A 3PYDA 4DR2I 3J80C 2PO2B 3T1YE 3K1JA 3HJCA 4FW9A 2C38A 2NN6A 5C0XC 1VI7A 2ZM6I 4NXNE 1N0VC 4IZJB 2JEBB 4U3DA 2LJPA 2O1WA 5ELWA 4LCFA 2V34A 2F4VI 1U2RA 3M7NG 1NHHA 4ISAA 3WU4A 4MYTA 4X65E 4DV6I 5LL6R 4LF9E 4ED4A 1MU5A 4DV1I 2GQ0A 5BR8I 1XXEA 4M1KA 4IFDE 2R3VA 2V2ZA 4OZEA 4FW4A 1PVGA 4GKJE 2V2QA 2UUBE 2JE6A 1EA6A 3P76A 4ZVIA 1NHIA 3J81C 2DEIA 5JEAF 4NXNI 1Z0CA 1E3HA 2EFGA 4Z7YA 2J7KA 4AQYE 2JEAA 4JI8I 3J81Q 4LF9I 4DXLA 4X65I 4IZJD 1J5EE 4HXZA 4NXME 4XTJA 1Z5CA 3K17A 3M85G 2BM0A 2V2VA 1E3PA 4QNJA 3K85A 4JI3E 4GKJI 5C0XE 2OI2A 4DR7E 4MU3A 4DPTA 3QT7A 2UUBI 5K36C 4EMDA 1FJGI 2AJ4A 1HNWE 3JAMC 1IBKE 1FWKA 4FW3A 2PO2A 2UXDE 3U1KA 3V2UC 4X66E 2GO4A 4MU1A 1P42A 4AQYI 2HFUA 1Y4SA 4IZJA 2BR2B 4DV3E 4FWHA 4P7AA 4FW7A 1N32E 3JAMQ 2Z5CA 1J5EI 3OTOE 4OO1A
chains in the Genus database with same CATH topology
1Y5YA 1Y60A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1Y5Y A;  1Y60 A; 
#chains in the Genus database with same CATH topology
 2NN6 C;  4DV0 E;  4NXM I;  4PU9 A;  4JI7 E;  5LMN E;  5LMU E;  4AM3 A;  2UU9 E;  2UXC E;  1VIS A;  2CVE A;  4JI3 I;  4DPY A;  4B3S E;  1N33 E;  2C37 B;  2PO0 B;  1N0U A;  1ZM2 A;  1HNW I;  1QZR A;  1IBK I;  2UXD I;  5DRP A;  4X66 I;  1FNM A;  3CDJ A;  1WUU A;  5GME A;  1H72 C;  4DV3 I;  2NPF A;  2CZ9 A;  4DPU A;  4BA2 B;  1B62 A;  3OTO I;  4IFD B;  4DV0 I;  5DRQ A;  4JI6 I;  5K36 E;  4JYA I;  2E1R A;  1XMQ E;  5LMN I;  3NZK A;  2UU9 I;  2UXC I;  1D6T A;  4RPF A;  4DU7 A;  4LPF A;  2A2D A;  3H4L A;  1USU A;  2JT2 A;  3GLL A;  4HAC A;  2WNR B;  2IES A;  3WU6 A;  2E5L E;  4DR5 E;  4X62 E;  3P3G A;  3HUL A;  4X64 E;  2UXB I;  3M7N D;  1IBL E;  2CGE A;  4DV5 E;  1NZ0 A;  1Z0E A;  2Z5B B;  5A2Q C;  3T1H E;  4DUZ E;  3ZZT A;  1ZM4 A;  2BR2 A;  3P06 A;  3Q6M A;  2HK2 A;  4LFC E;  3J80 Q;  5C0X B;  1PIE A;  1Y5Y A;  5GMD A;  2PNZ B;  3LPS A;  4LOM A;  4JI4 E;  4IFD D;  4B3R E;  1NHJ A;  1K47 A;  1ZXM A;  2E5L I;  4OO1 C;  4DR5 I;  2C37 A;  2PO0 A;  4BA1 B;  1XMO E;  4X62 I;  4JG4 A;  5DNL A;  4NBQ A;  4X64 I;  4LF5 E;  1ZM3 A;  1IBL I;  3T1Y I;  4DV5 I;  3CDI A;  3T1H I;  4DUZ I;  5IT9 C;  3QT8 A;  3M85 D;  4IS9 A;  1FWL A;  2C39 B;  3PRY A;  4DV2 E;  4GKK E;  4LFC I;  2F1D A;  2HFS A;  4IFD A;  2Z5E A;  4GQU A;  3LTO A;  4KQV A;  1IBM E;  4I3H A;  5IT9 Q;  4JV5 E;  2BV3 A;  4FW6 A;  5C0X D;  4DV4 E;  3LNU A;  1XMO I;  1UEK A;  2WNR A;  4LF5 I;  4WUC A;  1RRE A;  3PS2 A;  3DD6 A;  2WP8 B;  4HYM A;  4PRV A;  1KTV A;  3HKM A;  4DR3 E;  4OKG A;  2X7I A;  1FI4 A;  4N3O A;  4FN5 A;  4DR4 E;  4QNK A;  5DNX A;  2Z5B A;  4UTG A;  1H7U A;  5K36 B;  1N36 E;  4DV2 I;  4GKK I;  5JEA C;  2JEB A;  1Z0B A;  1ZXN A;  2GO3 A;  4LF4 E;  4DR6 E;  1HK7 A;  4LF7 E;  1KIJ A;  1IBM I;  5C0X A;  2ZBK B;  3ZZ0 A;  4JV5 I;  4K0K E;  4IFD F;  4P52 A;  1HNX E;  1OJ4 A;  1RHY A;  1I94 E;  4DR7 I;  2C38 B;  2NN6 B;  3B8H A;  3ZM7 A;  4DUY E;  2PNM A;  4FW5 A;  4LFA E;  4PRX A;  4OX9 E;  4DR3 I;  1N34 E;  3P3E A;  2VQF E;  4URL A;  4U3B A;  1Z0V A;  4DR4 I;  1N36 I;  4B3M E;  3M6A A;  1XHK A;  2WW4 A;  2BA1 G;  4LF4 I;  1N32 I;  4DR6 I;  4MDT A;  2VQE E;  2O3Z A;  1UDS A;  4LF7 I;  5K36 D;  2Q2E B;  5FLX C;  4JI7 I;  5LMU I;  4UT4 A;  2HHH E;  2JE6 B;  1A6F A;  4K0K I;  4IZK B;  1HNX I;  1MG7 A;  4B3S I;  3H1C A;  5C0X F;  1YHC A;  1N33 I;  3CWV A;  3PYG A;  2IER A;  4DU8 A;  5FLX Q;  4J3D A;  2ZM6 E;  4JI0 E;  2WP8 A;  3PYF A;  2VQF I;  2V8P A;  2NN6 D;  3B4T A;  5EL9 A;  2NN6 E;  4LCH A;  3ZKB A;  1OYR A;  1RR9 A;  1S16 A;  2HK3 A;  4B3M I;  4YHH E;  3P3C A;  5K36 A;  4DV6 E;  5DRO A;  1HR0 E;  2VQE I;  4HY1 A;  1Z0W A;  1FKA E;  4AIM A;  1XMQ I;  3GCM A;  3J7A M;  4DV7 E;  2HHH I;  4LF8 E;  4MU4 A;  2BM1 A;  5L3J A;  5A2Q Q;  1ZM9 A;  2O1V A;  4DPW A;  4B3T E;  2PO1 B;  1H74 A;  1B63 A;  4DR1 E;  4JI1 E;  3GME A;  2AE8 A;  2CG9 A;  4JI0 I;  1MX0 A;  1USV A;  2HKE A;  3WU5 A;  4FWG A;  4JI8 E;  3UHM A;  2Z5C B;  3PS1 A;  1XNQ E;  4YHH I;  4OO1 B;  1Z0T A;  2VF3 A;  3D4J A;  2IOQ A;  4MQY A;  4AID A;  3ZZU A;  1HR0 I;  1UDN A;  1Z5B A;  1BKN A;  4BA2 A;  3J7A G;  5FWK A;  5K36 F;  4DV7 I;  2VES A;  2HKJ A;  4LF8 I;  4WUB A;  2PNL A;  1YH8 A;  1FJG E;  4JI4 I;  1R6L A;  2UUC E;  4B3T I;  4IZK A;  4B3R I;  1EI1 A;  4DR1 I;  2R42 A;  5IWA E;  4JI1 I;  4MU0 A;  2IOP A;  4LFB E;  3Q6N A;  4MYU A;  1XNQ I;  3ZKD A;  2NN6 F;  2BA0 D;  2GS8 A;  5EKW A;  3L7Z B;  3U1Y A;  2O1T A;  4OO1 D;  4JI5 E;  4HAC B;  4OO1 E;  1PKP A;  2BA0 G;  4USK A;  4JI2 E;  3F0N A;  2UUC I;  5JEA B;  2PNZ A;  1Z59 A;  1ELO A;  4YY3 E;  5IWA I;  2PO1 A;  1OYP A;  4DV4 I;  4LFB I;  2BA1 D;  4BA1 A;  4DPX A;  4WUD A;  2XEX A;  1OYS A;  4JI6 E;  4USM A;  4R1F A;  4JYA E;  4KHP E;  4Z7C A;  2DEJ A;  1HNZ E;  1UDO A;  1UDQ A;  2C39 A;  4LCG A;  4JI5 I;  2UUA E;  4LF6 E;  1XNR E;  3Q1Q A;  1Y6Z A;  3PS3 A;  1Y60 A;  4JI2 I;  1H73 A;  3GON A;  1H7S A;  4FWD A;  4YY3 I;  3QT6 A;  2UXB E;  1KVK A;  3QT5 A;  4DR2 E;  1I94 I;  4DUY I;  4LFA I;  3KRN A;  4IFD C;  5JEA D;  3B78 A;  5JEA E;  4OX9 I;  1N34 I;  2JEA B;  2ZIT A;  1Z5A A;  5DRR A;  1S4E A;  3B82 A;  3V5R A;  2F4V E;  4KHP I;  1R6M A;  1HNZ I;  1Z0G A;  2X36 A;  3L7Z A;  1DAR A;  2UUA I;  4LF6 I;  1XNR I;  3PYE A;  2O1U A;  4DV1 E;  4OO1 F;  5BR8 E;  1Y4U A;  1KKH A;  2J65 A;  2A2C A;  5JEA A;  3WU3 A;  3PYD A;  4DR2 I;  3J80 C;  2PO2 B;  3T1Y E;  3K1J A;  3HJC A;  4FW9 A;  2C38 A;  2NN6 A;  5C0X C;  1VI7 A;  2ZM6 I;  4NXN E;  1N0V C;  4IZJ B;  2JEB B;  4U3D A;  2LJP A;  2O1W A;  5ELW A;  4LCF A;  2V34 A;  2F4V I;  1U2R A;  3M7N G;  1NHH A;  4ISA A;  3WU4 A;  4MYT A;  4X65 E;  4DV6 I;  5LL6 R;  4LF9 E;  4ED4 A;  1MU5 A;  4DV1 I;  2GQ0 A;  5BR8 I;  1XXE A;  4M1K A;  4IFD E;  2R3V A;  2V2Z A;  4OZE A;  4FW4 A;  1PVG A;  4GKJ E;  2V2Q A;  2UUB E;  2JE6 A;  1EA6 A;  3P76 A;  4ZVI A;  1NHI A;  3J81 C;  2DEI A;  5JEA F;  4NXN I;  1Z0C A;  1E3H A;  2EFG A;  4Z7Y A;  2J7K A;  4AQY E;  2JEA A;  4JI8 I;  3J81 Q;  4LF9 I;  4DXL A;  4X65 I;  4IZJ D;  1J5E E;  4HXZ A;  4NXM E;  4XTJ A;  1Z5C A;  3K17 A;  3M85 G;  2BM0 A;  2V2V A;  1E3P A;  4QNJ A;  3K85 A;  4JI3 E;  4GKJ I;  5C0X E;  2OI2 A;  4DR7 E;  4MU3 A;  4DPT A;  3QT7 A;  2UUB I;  5K36 C;  4EMD A;  1FJG I;  2AJ4 A;  1HNW E;  3JAM C;  1IBK E;  1FWK A;  4FW3 A;  2PO2 A;  2UXD E;  3U1K A;  3V2U C;  4X66 E;  2GO4 A;  4MU1 A;  1P42 A;  4AQY I;  2HFU A;  1Y4S A;  4IZJ A;  2BR2 B;  4DV3 E;  4FWH A;  4P7A A;  4FW7 A;  1N32 E;  3JAM Q;  2Z5C A;  1J5E I;  3OTO E;  4OO1 A; 
#chains in the Genus database with same CATH homology
 1Y5Y A;  1Y60 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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