2F1DA

X-ray structure of imidazoleglycerol-phosphate dehydratase
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
183
structure length
183
Chain Sequence
GRIGEVKRVTKETNVSVKINLDGTGVADSSSGIPFLDHMLDQLASHGLFDVHVRATGDVHIDDHHTNEDIALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGENSHHIIEATFKAFARALRQATETDPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of imidazoleglycerol-phosphate dehydratase.
pubmed doi rcsb
molecule tags Lyase
source organism Arabidopsis thaliana
molecule keywords Imidazoleglycerol-phosphate dehydratase 1
total genus 54
structure length 183
sequence length 183
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2005-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 2f1dA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 2f1dA02
4MU3A 4QNKA 4MU4A 2AE8A 4LOMA 4MU1A 5EL9A 5EKWA 1RHYA 5DNLA 4GQUA 5ELWA 4MU0A 4QNJA 4LPFA 5DNXA 2F1DA
chains in the Genus database with same CATH superfamily
3Q6MA 5JEAE 1J5EI 2ZITA 4DR5I 1ZXNA 1USUA 3M85D 4ED4A 4FWHA 2DEJA 2PO0A 3H4LA 3NZKA 2IESA 4DR5E 4LPFA 4IFDB 4LF8I 4UTGA 1PIEA 5IT9Q 5K36F 3P06A 4LFAI 2O1VA 2OI2A 4DR3I 4JI0I 1R6LA 5DRRA 4X65I 4OO1B 4OO1D 4JI8E 1Z0CA 2NN6B 4OO1C 5GMEA 4JI0E 3PYFA 1ZM3A 1ZM2A 4X65E 1HNZI 4OO1E 4MU1A 4IFDA 4R1FA 4DR4I 1B63A 1ZM4A 4JYAI 2E1RA 4FWDA 1Y60A 4J3DA 4AQYI 4DR4E 3U1YA 5DROA 3GCMA 4OO1A 1IBLE 4JI5I 3CWVA 2LJPA 4NXNI 4OKGA 4AQYE 3ZKDA 3PYEA 2UXCI 4DUYI 3WU3A 1N34I 1FNMA 4JI5E 1ELOA 5EKWA 1XHKA 5DRQA 1ZXMA 4FN5A 4X62I 4QNJA 1FI4A 4MDTA 5FLXC 2UXCE 4DUYE 5BR8E 1XMQI 4WUDA 1UDNA 4FW4A 4KQVA 3L7ZB 5GMDA 2JT2A 4MU0A 4LF4I 5JEAF 1XMQE 2IERA 4DR1E 4RPFA 1FJGI 2E5LE 2IOPA 3QT6A 1IBMI 4LF9E 2V2ZA 1OYRA 1HK7A 5C0XB 3PYGA 4DV4E 1K47A 3P3EA 3UHMA 1Z0BA 2O3ZA 3L7ZA 1XNQE 4MU3A 4LCHA 2PO2B 4FW5A 1HR0E 2WNRB 3OTOE 4HY1A 5FLXQ 4DV6I 2F4VI 4DUZI 5LL6R 1WUUA 4JI7I 3ZKBA 4GKJI 2F4VE 5C0XA 4DUZE 3P76A 2WP8B 4MYTA 4YHHI 4JI7E 2VQFI 4GKJE 5DRPA 1USVA 4DPTA 2PO2A 2UUBI 2WNRA 3J7AG 4B3RI 4JG4A 4KHPI 4LF6I 4USKA 1N0UA 1FWLA 4U3BA 3QT5A 2GO4A 1KTVA 1Y6ZA 4PU9A 1OYSA 2VESA 4GKKE 4KHPE 2V8PA 5ELWA 5L3JA 4LF6E 2WW4A 1Y4SA 4OX9I 3QT7A 3PS1A 3HKMA 4DV3I 2WP8A 4ZVIA 4EMDA 1J5EE 3T1YI 4IFDD 4OX9E 4FW6A 1E3PA 4IFDC 3KRNA 3J81C 4USMA 4IFDE 3K85A 4LCGA 1HNWI 4LF8E 4DPWA 1S4EA 2BA0G 4LFAE 2HFUA 4DR3E 2NN6D 4X64I 4YY3I 4LF5I 1FWKA 3F0NA 2NN6C 3V5RA 4UT4A 3ZZTA 1IBKI 1NZ0A 1KIJA 1P42A 2UU9I 2NN6E 3P3CA 4DR6I 1Z5CA 4LOMA 4DR2I 2BA1G 2C37B 1HNZE 4U3DA 3ZZUA 3ZZ0A 2BR2B 1VISA 3CDIA 4DV1I 1E3HA 4JYAE 2Z5BB 4IZJB 1Z5AA 4DR2E 2NN6A 1S16A 4IZKB 3J81Q 1PKPA 5LMNI 4MQYA 4NXNE 1NHIA 4JV5I 4IS9A 4ISAA 2C37A 2BR2A 5EL9A 1N34E 1NHJA 2Z5BA 1RREA 4IZJA 1H73A 2VQEI 4X62E 2PO1B 1UDQA 2AE8A 1OJ4A 3HULA 4DV0I 4JI4I 4IZKA 1Z59A 4QNKA 4X66I 2VQEE 1VI7A 4AIMA 2C38B 3U1KA 3J80Q 2O1WA 5K36B 4BA1B 2UUCI 2HFSA 4JI6I 4LF4E 5A2QC 5DNXA 5C0XD 1FJGE 2V2QA 2R3VA 5C0XC 1I94I 2BA0D 2PO1A 4LFBI 4JI6E 2X36A 1EI1A 3LTOA 1IBME 2UXDI 1H74A 4K0KI 1RR9A 5C0XE 4IFDF 2UXBI 3GMEA 1N0VC 2BM0A 1XMOI 1XNRI 2C38A 2AJ4A 2ZM6I 2CVEA 1KVKA 3WU4A 2V34A 2BA1D 1XNRE 4OO1F 4DV6E 2HHHI 4DPUA 4WUBA 2NN6F 3M6AA 2PNLA 4BA2B 2XEXA 4NXMI 4B3SI 2CGEA 2HHHE 4PRVA 2ZBKB 1DARA 2O1TA 4DV2I 5A2QQ 2Z5EA 4YHHE 1Z0TA 4HACB 4B3MI 2VQFE 2HK2A 1Z0WA 2O1UA 4JI1I 1N32I 2HK3A 3GONA 1Z0GA 1Y5YA 2BM1A 2UUBE 1R6MA 4DV2E 2DEIA 4B3RE 1U2RA 4DV5I 2GO3A 1RHYA 4FW9A 2PNMA 1EA6A 3P3GA 3HJCA 3B4TA 1A6FA 1QZRA 5JEAB 4WUCA 3D4JA 4DV3E 4HACA 4URLA 3WU5A 3T1YE 4DPXA 4GQUA 4AM3A 4JI3I 3B78A 3LPSA 4P52A 3J7AM 4PRXA 2HKJA 4JI3E 1HNWE 1FKAE 2JE6B 3QT8A 4B3TI 5JEAA 2J7KA 4X64E 4YY3E 4LF5E 1NHHA 4OZEA 4JI8I 2JEBB 4DU8A 2A2DA 1IBKE 2UU9E 4B3TE 5C0XF 3J80C 4DR6E 5DNLA 4IZJD 5FWKA 3M7NG 3PYDA 4DV1E 2JE6A 1D6TA 1H72C 1XXEA 1Z5BA 1IBLI 3ZM7A 2JEBA 1MX0A 3H1CA 2NPFA 1PVGA 1BKNA 5LMNE 2PNZB 2CG9A 4FW3A 4DR7I 4Z7CA 5LMUI 4DPYA 4JV5E 4LFCI 1MG7A 2IOQA 3PRYA 4JI2I 4DR7E 5LMUE 2HKEA 5BR8I 2F1DA 3WU6A 4LFCE 4DV0E 4JI4E 2Z5CB 3GLLA 5K36D 4JI2E 3JAMC 5K36C 4M1KA 4X66E 4DXLA 1KKHA 4AIDA 4MYUA 2EFGA 2PNZA 5K36E 3M85G 1Z0EA 2UUCE 4DR1I 3K17A 2GQ0A 3K1JA 2E5LI 2BV3A 2J65A 5IWAI 3DD6A 4LF9I 3PS2A 1I94E 3LNUA 4LFBE 4I3HA 2X7IA 2UXDE 4K0KE 4P7AA 1H7UA 2C39B 2Z5CA 5K36A 2UXBE 3B82A 4BA1A 4DV4I 5IWAE 4FW7A 1ZM9A 1N36I 1XNQI 4HXZA 1XMOE 1YH8A 4DV7I 1HR0I 2R42A 2ZM6E 3OTOI 3Q1QA 1N36E 3M7ND 3V2UC 4NBQA 4DU7A 4DV7E 2Q2EB 2JEAB 2UUAI 3JAMQ 1HNXI 1MU5A 1UEKA 3CDJA 2V2VA 4NXME 4B3SE 1N33I 2C39A 4Z7YA 2CZ9A 2GS8A 2UUAE 3T1HI 5IT9C 1Z0VA 1HNXE 3Q6NA 4FWGA 4B3ME 4LF7I 4MU4A 2VF3A 4JI1E 1N32E 1N33E 3B8HA 3T1HE 2PO0B 4BA2A 4DV5E 4HYMA 4LCFA 4XTJA 4LF7E 2JEAA 5JEAD 4N3OA 4GKKI 1UDOA 1Y4UA 1B62A 5JEAC 2A2CA 1YHCA 3PS3A 1OYPA 1UDSA 1H7SA
chains in the Genus database with same CATH topology
4MU3A 4QNKA 4MU4A 2AE8A 4LOMA 4MU1A 5EL9A 5EKWA 1RHYA 5DNLA 4GQUA 5ELWA 4MU0A 4QNJA 4LPFA 5DNXA 2F1DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MU3 A;  4QNK A;  4MU4 A;  2AE8 A;  4LOM A;  4MU1 A;  5EL9 A;  5EKW A;  1RHY A;  5DNL A;  4GQU A;  5ELW A;  4MU0 A;  4QNJ A;  4LPF A;  5DNX A;  2F1D A; 
#chains in the Genus database with same CATH topology
 3Q6M A;  5JEA E;  1J5E I;  2ZIT A;  4DR5 I;  1ZXN A;  1USU A;  3M85 D;  4ED4 A;  4FWH A;  2DEJ A;  2PO0 A;  3H4L A;  3NZK A;  2IES A;  4DR5 E;  4LPF A;  4IFD B;  4LF8 I;  4UTG A;  1PIE A;  5IT9 Q;  5K36 F;  3P06 A;  4LFA I;  2O1V A;  2OI2 A;  4DR3 I;  4JI0 I;  1R6L A;  5DRR A;  4X65 I;  4OO1 B;  4OO1 D;  4JI8 E;  1Z0C A;  2NN6 B;  4OO1 C;  5GME A;  4JI0 E;  3PYF A;  1ZM3 A;  1ZM2 A;  4X65 E;  1HNZ I;  4OO1 E;  4MU1 A;  4IFD A;  4R1F A;  4DR4 I;  1B63 A;  1ZM4 A;  4JYA I;  2E1R A;  4FWD A;  1Y60 A;  4J3D A;  4AQY I;  4DR4 E;  3U1Y A;  5DRO A;  3GCM A;  4OO1 A;  1IBL E;  4JI5 I;  3CWV A;  2LJP A;  4NXN I;  4OKG A;  4AQY E;  3ZKD A;  3PYE A;  2UXC I;  4DUY I;  3WU3 A;  1N34 I;  1FNM A;  4JI5 E;  1ELO A;  5EKW A;  1XHK A;  5DRQ A;  1ZXM A;  4FN5 A;  4X62 I;  4QNJ A;  1FI4 A;  4MDT A;  5FLX C;  2UXC E;  4DUY E;  5BR8 E;  1XMQ I;  4WUD A;  1UDN A;  4FW4 A;  4KQV A;  3L7Z B;  5GMD A;  2JT2 A;  4MU0 A;  4LF4 I;  5JEA F;  1XMQ E;  2IER A;  4DR1 E;  4RPF A;  1FJG I;  2E5L E;  2IOP A;  3QT6 A;  1IBM I;  4LF9 E;  2V2Z A;  1OYR A;  1HK7 A;  5C0X B;  3PYG A;  4DV4 E;  1K47 A;  3P3E A;  3UHM A;  1Z0B A;  2O3Z A;  3L7Z A;  1XNQ E;  4MU3 A;  4LCH A;  2PO2 B;  4FW5 A;  1HR0 E;  2WNR B;  3OTO E;  4HY1 A;  5FLX Q;  4DV6 I;  2F4V I;  4DUZ I;  5LL6 R;  1WUU A;  4JI7 I;  3ZKB A;  4GKJ I;  2F4V E;  5C0X A;  4DUZ E;  3P76 A;  2WP8 B;  4MYT A;  4YHH I;  4JI7 E;  2VQF I;  4GKJ E;  5DRP A;  1USV A;  4DPT A;  2PO2 A;  2UUB I;  2WNR A;  3J7A G;  4B3R I;  4JG4 A;  4KHP I;  4LF6 I;  4USK A;  1N0U A;  1FWL A;  4U3B A;  3QT5 A;  2GO4 A;  1KTV A;  1Y6Z A;  4PU9 A;  1OYS A;  2VES A;  4GKK E;  4KHP E;  2V8P A;  5ELW A;  5L3J A;  4LF6 E;  2WW4 A;  1Y4S A;  4OX9 I;  3QT7 A;  3PS1 A;  3HKM A;  4DV3 I;  2WP8 A;  4ZVI A;  4EMD A;  1J5E E;  3T1Y I;  4IFD D;  4OX9 E;  4FW6 A;  1E3P A;  4IFD C;  3KRN A;  3J81 C;  4USM A;  4IFD E;  3K85 A;  4LCG A;  1HNW I;  4LF8 E;  4DPW A;  1S4E A;  2BA0 G;  4LFA E;  2HFU A;  4DR3 E;  2NN6 D;  4X64 I;  4YY3 I;  4LF5 I;  1FWK A;  3F0N A;  2NN6 C;  3V5R A;  4UT4 A;  3ZZT A;  1IBK I;  1NZ0 A;  1KIJ A;  1P42 A;  2UU9 I;  2NN6 E;  3P3C A;  4DR6 I;  1Z5C A;  4LOM A;  4DR2 I;  2BA1 G;  2C37 B;  1HNZ E;  4U3D A;  3ZZU A;  3ZZ0 A;  2BR2 B;  1VIS A;  3CDI A;  4DV1 I;  1E3H A;  4JYA E;  2Z5B B;  4IZJ B;  1Z5A A;  4DR2 E;  2NN6 A;  1S16 A;  4IZK B;  3J81 Q;  1PKP A;  5LMN I;  4MQY A;  4NXN E;  1NHI A;  4JV5 I;  4IS9 A;  4ISA A;  2C37 A;  2BR2 A;  5EL9 A;  1N34 E;  1NHJ A;  2Z5B A;  1RRE A;  4IZJ A;  1H73 A;  2VQE I;  4X62 E;  2PO1 B;  1UDQ A;  2AE8 A;  1OJ4 A;  3HUL A;  4DV0 I;  4JI4 I;  4IZK A;  1Z59 A;  4QNK A;  4X66 I;  2VQE E;  1VI7 A;  4AIM A;  2C38 B;  3U1K A;  3J80 Q;  2O1W A;  5K36 B;  4BA1 B;  2UUC I;  2HFS A;  4JI6 I;  4LF4 E;  5A2Q C;  5DNX A;  5C0X D;  1FJG E;  2V2Q A;  2R3V A;  5C0X C;  1I94 I;  2BA0 D;  2PO1 A;  4LFB I;  4JI6 E;  2X36 A;  1EI1 A;  3LTO A;  1IBM E;  2UXD I;  1H74 A;  4K0K I;  1RR9 A;  5C0X E;  4IFD F;  2UXB I;  3GME A;  1N0V C;  2BM0 A;  1XMO I;  1XNR I;  2C38 A;  2AJ4 A;  2ZM6 I;  2CVE A;  1KVK A;  3WU4 A;  2V34 A;  2BA1 D;  1XNR E;  4OO1 F;  4DV6 E;  2HHH I;  4DPU A;  4WUB A;  2NN6 F;  3M6A A;  2PNL A;  4BA2 B;  2XEX A;  4NXM I;  4B3S I;  2CGE A;  2HHH E;  4PRV A;  2ZBK B;  1DAR A;  2O1T A;  4DV2 I;  5A2Q Q;  2Z5E A;  4YHH E;  1Z0T A;  4HAC B;  4B3M I;  2VQF E;  2HK2 A;  1Z0W A;  2O1U A;  4JI1 I;  1N32 I;  2HK3 A;  3GON A;  1Z0G A;  1Y5Y A;  2BM1 A;  2UUB E;  1R6M A;  4DV2 E;  2DEI A;  4B3R E;  1U2R A;  4DV5 I;  2GO3 A;  1RHY A;  4FW9 A;  2PNM A;  1EA6 A;  3P3G A;  3HJC A;  3B4T A;  1A6F A;  1QZR A;  5JEA B;  4WUC A;  3D4J A;  4DV3 E;  4HAC A;  4URL A;  3WU5 A;  3T1Y E;  4DPX A;  4GQU A;  4AM3 A;  4JI3 I;  3B78 A;  3LPS A;  4P52 A;  3J7A M;  4PRX A;  2HKJ A;  4JI3 E;  1HNW E;  1FKA E;  2JE6 B;  3QT8 A;  4B3T I;  5JEA A;  2J7K A;  4X64 E;  4YY3 E;  4LF5 E;  1NHH A;  4OZE A;  4JI8 I;  2JEB B;  4DU8 A;  2A2D A;  1IBK E;  2UU9 E;  4B3T E;  5C0X F;  3J80 C;  4DR6 E;  5DNL A;  4IZJ D;  5FWK A;  3M7N G;  3PYD A;  4DV1 E;  2JE6 A;  1D6T A;  1H72 C;  1XXE A;  1Z5B A;  1IBL I;  3ZM7 A;  2JEB A;  1MX0 A;  3H1C A;  2NPF A;  1PVG A;  1BKN A;  5LMN E;  2PNZ B;  2CG9 A;  4FW3 A;  4DR7 I;  4Z7C A;  5LMU I;  4DPY A;  4JV5 E;  4LFC I;  1MG7 A;  2IOQ A;  3PRY A;  4JI2 I;  4DR7 E;  5LMU E;  2HKE A;  5BR8 I;  2F1D A;  3WU6 A;  4LFC E;  4DV0 E;  4JI4 E;  2Z5C B;  3GLL A;  5K36 D;  4JI2 E;  3JAM C;  5K36 C;  4M1K A;  4X66 E;  4DXL A;  1KKH A;  4AID A;  4MYU A;  2EFG A;  2PNZ A;  5K36 E;  3M85 G;  1Z0E A;  2UUC E;  4DR1 I;  3K17 A;  2GQ0 A;  3K1J A;  2E5L I;  2BV3 A;  2J65 A;  5IWA I;  3DD6 A;  4LF9 I;  3PS2 A;  1I94 E;  3LNU A;  4LFB E;  4I3H A;  2X7I A;  2UXD E;  4K0K E;  4P7A A;  1H7U A;  2C39 B;  2Z5C A;  5K36 A;  2UXB E;  3B82 A;  4BA1 A;  4DV4 I;  5IWA E;  4FW7 A;  1ZM9 A;  1N36 I;  1XNQ I;  4HXZ A;  1XMO E;  1YH8 A;  4DV7 I;  1HR0 I;  2R42 A;  2ZM6 E;  3OTO I;  3Q1Q A;  1N36 E;  3M7N D;  3V2U C;  4NBQ A;  4DU7 A;  4DV7 E;  2Q2E B;  2JEA B;  2UUA I;  3JAM Q;  1HNX I;  1MU5 A;  1UEK A;  3CDJ A;  2V2V A;  4NXM E;  4B3S E;  1N33 I;  2C39 A;  4Z7Y A;  2CZ9 A;  2GS8 A;  2UUA E;  3T1H I;  5IT9 C;  1Z0V A;  1HNX E;  3Q6N A;  4FWG A;  4B3M E;  4LF7 I;  4MU4 A;  2VF3 A;  4JI1 E;  1N32 E;  1N33 E;  3B8H A;  3T1H E;  2PO0 B;  4BA2 A;  4DV5 E;  4HYM A;  4LCF A;  4XTJ A;  4LF7 E;  2JEA A;  5JEA D;  4N3O A;  4GKK I;  1UDO A;  1Y4U A;  1B62 A;  5JEA C;  2A2C A;  1YHC A;  3PS3 A;  1OYP A;  1UDS A;  1H7S A; 
#chains in the Genus database with same CATH homology
 4MU3 A;  4QNK A;  4MU4 A;  2AE8 A;  4LOM A;  4MU1 A;  5EL9 A;  5EKW A;  1RHY A;  5DNL A;  4GQU A;  5ELW A;  4MU0 A;  4QNJ A;  4LPF A;  5DNX A;  2F1D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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