2F1DA

X-ray structure of imidazoleglycerol-phosphate dehydratase
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
183
structure length
183
Chain Sequence
GRIGEVKRVTKETNVSVKINLDGTGVADSSSGIPFLDHMLDQLASHGLFDVHVRATGDVHIDDHHTNEDIALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGENSHHIIEATFKAFARALRQATETDPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of imidazoleglycerol-phosphate dehydratase.
pubmed doi rcsb
molecule tags Lyase
source organism Arabidopsis thaliana
molecule keywords Imidazoleglycerol-phosphate dehydratase 1
total genus 54
structure length 183
sequence length 183
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2005-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 2f1dA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 2f1dA02
2AE8A 4LPFA 4MU3A 2F1DA 4MU4A 5EL9A 4MU1A 4LOMA 4QNJA 5EKWA 4QNKA 4MU0A 5DNLA 4GQUA 5DNXA 5ELWA 1RHYA
chains in the Genus database with same CATH superfamily
4B3RI 2OI2A 2HFSA 4DUZI 4JI1I 1S4EA 3PYFA 4DU8A 2Z5EA 4URLA 2HHHE 5K36B 4X62I 4IZKB 4DR7E 1R6LA 4WUDA 2C38B 4DR2E 3J81C 2JT2A 4JI7E 4LF5I 4MU3A 3J7AG 4B3TI 3HJCA 1ZM2A 4LCHA 1H7SA 5BR8E 1PKPA 2J65A 4JI0I 4JI5E 1ZM4A 5LMNE 3OTOI 3V5RA 4DR5E 1FWLA 2ZBKB 4JYAI 4M1KA 4MDTA 4DPUA 4LF6I 2UXDI 1HNZE 1Z0BA 3QT8A 4MYTA 5JEAA 4GQUA 5LMUI 4IS9A 4FN5A 4OX9I 1YHCA 3PYGA 2JE6B 5FLXC 1N36I 3HULA 1USUA 1EI1A 4FWGA 5GMEA 5C0XA 3Q6NA 4GKJE 1RHYA 2VQFI 4XTJA 1IBMI 4DR3E 4IZJB 2E5LE 4USMA 2IESA 1N32I 4QNKA 1KVKA 2ZM6I 2WP8B 3CWVA 2GS8A 1VI7A 1ZXMA 4FWHA 4ZVIA 4DV0E 4PRXA 3GMEA 1XMOI 2HKJA 5FLXQ 2BA0G 1FJGI 1NZ0A 2BR2A 2UUCE 4HXZA 3KRNA 1N0UA 3WU3A 4DPTA 1XMQI 1FKAE 5DRPA 4K0KE 2AE8A 2UXCI 3ZZUA 4X65E 1XNRI 3J81Q 1E3HA 5K36A 4OZEA 1D6TA 4DV4E 2JEBB 2UXBI 1FWKA 4P7AA 4IZKA 1Z0TA 2C38A 4LF9E 1N33I 5JEAB 1H72C 3ZZ0A 3K85A 4FW6A 4LFCI 4DV1E 3T1HE 1I94I 1H74A 3LPSA 3K1JA 4USKA 3ZKDA 4AQYE 4NBQA 3PYDA 4IFDE 4JI4I 1ZM9A 1Z0WA 1J5EI 5ELWA 1HNXE 4X66I 1UDSA 4UT4A 2UU9I 5DROA 2X7IA 2BR2B 3H1CA 3WU5A 2VQEI 4YY3I 4JI6E 2XEXA 4X64I 3B4TA 2AJ4A 3LNUA 4GKKI 4RPFA 1UDQA 3D4JA 2NN6C 4OO1B 4I3HA 2GO4A 2A2DA 4DV3I 1IBKE 1Y6ZA 2WP8A 4MYUA 2PO0A 4DR1I 2UUBE 2WNRA 1MU5A 2PNZB 4B3SE 1IBLI 3U1YA 4KHPE 2HK2A 1Z5BA 1Z0GA 3ZZTA 5C0XF 4JI3E 4FW7A 2HHHI 4DR6E 5C0XE 4ISAA 4MU1A 2IERA 1MX0A 3P06A 1A6FA 3QT5A 4IFDC 4JI7I 4DPXA 3WU6A 1NHIA 2GO3A 3K17A 2JEBA 5BR8I 1HNWE 2NN6D 5EKWA 2UUAE 4JI5I 4DPWA 4LF4E 1EA6A 5LMNI 2PNLA 1FNMA 4DR5I 1UDOA 4DU7A 3OTOE 2NPFA 4MU4A 1Z0VA 1ELOA 5K36F 3ZM7A 1HNZI 4U3DA 4DPYA 4AM3A 1HR0E 4LCFA 5K36E 2BA0D 4J3DA 2CG9A 3J7AM 2F4VE 3CDJA 1Z0CA 2PO0B 4GKJI 2WNRB 4DR3I 2V2VA 2E5LI 4IFDD 5LL6R 4NXNE 1WUUA 2Z5CB 4DV0I 2F1DA 1Y4SA 1XNQE 4QNJA 4DV2E 4OO1A 4DR4E 2O1WA 4HY1A 3B8HA 2UUCI 3ZKBA 3PS2A 4DV6E 3GLLA 2NN6B 5GMDA 3P3CA 3L7ZB 5DRRA 2O1TA 2BA1G 2PNZA 1B63A 3M7ND 4LFAE 4K0KI 4MQYA 3U1KA 4BA2A 1XMQE 1P42A 1Y5YA 1BKNA 1MG7A 4X65I 1OYPA 2PO1A 3P3EA 1PVGA 4DV4I 3M7NG 1HK7A 1Y4UA 1Z5CA 1OYSA 4EMDA 3T1YE 4WUCA 4JV5E 3V2UC 4HACB 3GCMA 4LF9I 4LF8E 4B3ME 1UDNA 4IFDB 4DV1I 3T1HI 1Z0EA 1PIEA 2JEAB 4JI2E 1U2RA 2E1RA 2V8PA 4DV7E 4DUYE 3NZKA 2DEJA 3P3GA 3CDIA 4JG4A 1FI4A 4NXME 1S16A 1HNXI 4FW9A 4JI8E 3JAMC 4YHHE 4DV5E 2BM1A 3HKMA 3F0NA 4LF7E 4JI6I 5IT9C 4LFBE 5JEAF 4BA1B 1IBKI 1N34E 5IWAE 1ZXNA 4BA2B 2Z5CA 5JEAE 2BM0A 2UUBI 1OYRA 4B3SI 4B3RE 2Q2EB 2PO1B 1Z59A 1KIJA 1Z5AA 4DUZE 4KHPI 1KTVA 2O1UA 4JI1E 2CGEA 4DR7I 4JI3I 2LJPA 2NN6A 4FW4A 1VISA 3L7ZA 4DR2I 4LOMA 4DR6I 4X62E 2Z5BA 1Y60A 2A2CA 4IZJD 4LPFA 4Z7CA 2C39B 2J7KA 2VESA 4KQVA 4LF5E 4B3TE 1H7UA 4OO1F 5JEAC 1K47A 2PO2A 5A2QC 1HNWI 3P76A 4OO1E 4JI0E 4PU9A 2R3VA 4FWDA 2BV3A 1RREA 1XXEA 5C0XC 2UUAI 3QT6A 4AIDA 4LF4I 4HACA 3DD6A 2HFUA 4JYAE 5EL9A 1DARA 4IFDA 3B78A 4LF6E 4AIMA 2UXDE 2EFGA 1ZM3A 1KKHA 5LMUE 1UEKA 4OX9E 4OKGA 4FW3A 3UHMA 2JEAA 2HKEA 1HR0I 1N36E 3Q1QA 3JAMQ 2F4VI 5L3JA 1IBME 2VQFE 2C37B 3Q6MA 4UTGA 4OO1C 1N32E 5IT9Q 2ZM6E 2BA1D 1QZRA 3J80C 4NXNI 3M6AA 5JEAD 3B82A 1RR9A 2DEIA 1XMOE 5DNLA 5K36C 1XNQI 1FJGE 4DV2I 1XHKA 5C0XD 4DR4I 2Z5BB 2O3ZA 4BA1A 1N0VC 5DRQA 2ZITA 3M85D 4DV6I 1NHJA 3PYEA 1R6MA 4N3OA 4LFAI 4MU0A 1B62A 2IOPA 2UXCE 2PO2B 4DXLA 2CVEA 4LCGA 4P52A 3M85G 1XNRE 3GONA 2IOQA 4WUBA 2HK3A 2UXBE 1OJ4A 1USVA 1H73A 4FW5A 4OO1D 4Z7YA 3PS3A 5A2QQ 3WU4A 3T1YI 2C39A 4JV5I 1N33E 3QT7A 4LF8I 4B3MI 4LFCE 4PRVA 1I94E 2R42A 4U3BA 4AQYI 2V2QA 5K36D 3H4LA 2NN6F 1IBLE 2VF3A 4R1FA 4JI2I 2GQ0A 2NN6E 2V34A 4DV7I 5DNXA 4DUYI 5C0XB 4JI4E 1YH8A 1J5EE 5FWKA 4X66E 4NXMI 2UU9E 1NHHA 2CZ9A 4HYMA 4JI8I 3PS1A 4YHHI 4DV5I 2VQEE 3J80Q 4YY3E 4X64E 4LF7I 2V2ZA 4GKKE 2C37A 2X36A 4DV3E 1E3PA 4LFBI 2JE6A 3PRYA 1N34I 5IWAI 2O1VA 4IFDF 2PNMA 4DR1E 4IZJA 2WW4A 3LTOA 4ED4A
chains in the Genus database with same CATH topology
2AE8A 4LPFA 4MU3A 2F1DA 4MU4A 5EL9A 4MU1A 4LOMA 4QNJA 5EKWA 4QNKA 4MU0A 5DNLA 4GQUA 5DNXA 5ELWA 1RHYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AE8 A;  4LPF A;  4MU3 A;  2F1D A;  4MU4 A;  5EL9 A;  4MU1 A;  4LOM A;  4QNJ A;  5EKW A;  4QNK A;  4MU0 A;  5DNL A;  4GQU A;  5DNX A;  5ELW A;  1RHY A; 
#chains in the Genus database with same CATH topology
 4B3R I;  2OI2 A;  2HFS A;  4DUZ I;  4JI1 I;  1S4E A;  3PYF A;  4DU8 A;  2Z5E A;  4URL A;  2HHH E;  5K36 B;  4X62 I;  4IZK B;  4DR7 E;  1R6L A;  4WUD A;  2C38 B;  4DR2 E;  3J81 C;  2JT2 A;  4JI7 E;  4LF5 I;  4MU3 A;  3J7A G;  4B3T I;  3HJC A;  1ZM2 A;  4LCH A;  1H7S A;  5BR8 E;  1PKP A;  2J65 A;  4JI0 I;  4JI5 E;  1ZM4 A;  5LMN E;  3OTO I;  3V5R A;  4DR5 E;  1FWL A;  2ZBK B;  4JYA I;  4M1K A;  4MDT A;  4DPU A;  4LF6 I;  2UXD I;  1HNZ E;  1Z0B A;  3QT8 A;  4MYT A;  5JEA A;  4GQU A;  5LMU I;  4IS9 A;  4FN5 A;  4OX9 I;  1YHC A;  3PYG A;  2JE6 B;  5FLX C;  1N36 I;  3HUL A;  1USU A;  1EI1 A;  4FWG A;  5GME A;  5C0X A;  3Q6N A;  4GKJ E;  1RHY A;  2VQF I;  4XTJ A;  1IBM I;  4DR3 E;  4IZJ B;  2E5L E;  4USM A;  2IES A;  1N32 I;  4QNK A;  1KVK A;  2ZM6 I;  2WP8 B;  3CWV A;  2GS8 A;  1VI7 A;  1ZXM A;  4FWH A;  4ZVI A;  4DV0 E;  4PRX A;  3GME A;  1XMO I;  2HKJ A;  5FLX Q;  2BA0 G;  1FJG I;  1NZ0 A;  2BR2 A;  2UUC E;  4HXZ A;  3KRN A;  1N0U A;  3WU3 A;  4DPT A;  1XMQ I;  1FKA E;  5DRP A;  4K0K E;  2AE8 A;  2UXC I;  3ZZU A;  4X65 E;  1XNR I;  3J81 Q;  1E3H A;  5K36 A;  4OZE A;  1D6T A;  4DV4 E;  2JEB B;  2UXB I;  1FWK A;  4P7A A;  4IZK A;  1Z0T A;  2C38 A;  4LF9 E;  1N33 I;  5JEA B;  1H72 C;  3ZZ0 A;  3K85 A;  4FW6 A;  4LFC I;  4DV1 E;  3T1H E;  1I94 I;  1H74 A;  3LPS A;  3K1J A;  4USK A;  3ZKD A;  4AQY E;  4NBQ A;  3PYD A;  4IFD E;  4JI4 I;  1ZM9 A;  1Z0W A;  1J5E I;  5ELW A;  1HNX E;  4X66 I;  1UDS A;  4UT4 A;  2UU9 I;  5DRO A;  2X7I A;  2BR2 B;  3H1C A;  3WU5 A;  2VQE I;  4YY3 I;  4JI6 E;  2XEX A;  4X64 I;  3B4T A;  2AJ4 A;  3LNU A;  4GKK I;  4RPF A;  1UDQ A;  3D4J A;  2NN6 C;  4OO1 B;  4I3H A;  2GO4 A;  2A2D A;  4DV3 I;  1IBK E;  1Y6Z A;  2WP8 A;  4MYU A;  2PO0 A;  4DR1 I;  2UUB E;  2WNR A;  1MU5 A;  2PNZ B;  4B3S E;  1IBL I;  3U1Y A;  4KHP E;  2HK2 A;  1Z5B A;  1Z0G A;  3ZZT A;  5C0X F;  4JI3 E;  4FW7 A;  2HHH I;  4DR6 E;  5C0X E;  4ISA A;  4MU1 A;  2IER A;  1MX0 A;  3P06 A;  1A6F A;  3QT5 A;  4IFD C;  4JI7 I;  4DPX A;  3WU6 A;  1NHI A;  2GO3 A;  3K17 A;  2JEB A;  5BR8 I;  1HNW E;  2NN6 D;  5EKW A;  2UUA E;  4JI5 I;  4DPW A;  4LF4 E;  1EA6 A;  5LMN I;  2PNL A;  1FNM A;  4DR5 I;  1UDO A;  4DU7 A;  3OTO E;  2NPF A;  4MU4 A;  1Z0V A;  1ELO A;  5K36 F;  3ZM7 A;  1HNZ I;  4U3D A;  4DPY A;  4AM3 A;  1HR0 E;  4LCF A;  5K36 E;  2BA0 D;  4J3D A;  2CG9 A;  3J7A M;  2F4V E;  3CDJ A;  1Z0C A;  2PO0 B;  4GKJ I;  2WNR B;  4DR3 I;  2V2V A;  2E5L I;  4IFD D;  5LL6 R;  4NXN E;  1WUU A;  2Z5C B;  4DV0 I;  2F1D A;  1Y4S A;  1XNQ E;  4QNJ A;  4DV2 E;  4OO1 A;  4DR4 E;  2O1W A;  4HY1 A;  3B8H A;  2UUC I;  3ZKB A;  3PS2 A;  4DV6 E;  3GLL A;  2NN6 B;  5GMD A;  3P3C A;  3L7Z B;  5DRR A;  2O1T A;  2BA1 G;  2PNZ A;  1B63 A;  3M7N D;  4LFA E;  4K0K I;  4MQY A;  3U1K A;  4BA2 A;  1XMQ E;  1P42 A;  1Y5Y A;  1BKN A;  1MG7 A;  4X65 I;  1OYP A;  2PO1 A;  3P3E A;  1PVG A;  4DV4 I;  3M7N G;  1HK7 A;  1Y4U A;  1Z5C A;  1OYS A;  4EMD A;  3T1Y E;  4WUC A;  4JV5 E;  3V2U C;  4HAC B;  3GCM A;  4LF9 I;  4LF8 E;  4B3M E;  1UDN A;  4IFD B;  4DV1 I;  3T1H I;  1Z0E A;  1PIE A;  2JEA B;  4JI2 E;  1U2R A;  2E1R A;  2V8P A;  4DV7 E;  4DUY E;  3NZK A;  2DEJ A;  3P3G A;  3CDI A;  4JG4 A;  1FI4 A;  4NXM E;  1S16 A;  1HNX I;  4FW9 A;  4JI8 E;  3JAM C;  4YHH E;  4DV5 E;  2BM1 A;  3HKM A;  3F0N A;  4LF7 E;  4JI6 I;  5IT9 C;  4LFB E;  5JEA F;  4BA1 B;  1IBK I;  1N34 E;  5IWA E;  1ZXN A;  4BA2 B;  2Z5C A;  5JEA E;  2BM0 A;  2UUB I;  1OYR A;  4B3S I;  4B3R E;  2Q2E B;  2PO1 B;  1Z59 A;  1KIJ A;  1Z5A A;  4DUZ E;  4KHP I;  1KTV A;  2O1U A;  4JI1 E;  2CGE A;  4DR7 I;  4JI3 I;  2LJP A;  2NN6 A;  4FW4 A;  1VIS A;  3L7Z A;  4DR2 I;  4LOM A;  4DR6 I;  4X62 E;  2Z5B A;  1Y60 A;  2A2C A;  4IZJ D;  4LPF A;  4Z7C A;  2C39 B;  2J7K A;  2VES A;  4KQV A;  4LF5 E;  4B3T E;  1H7U A;  4OO1 F;  5JEA C;  1K47 A;  2PO2 A;  5A2Q C;  1HNW I;  3P76 A;  4OO1 E;  4JI0 E;  4PU9 A;  2R3V A;  4FWD A;  2BV3 A;  1RRE A;  1XXE A;  5C0X C;  2UUA I;  3QT6 A;  4AID A;  4LF4 I;  4HAC A;  3DD6 A;  2HFU A;  4JYA E;  5EL9 A;  1DAR A;  4IFD A;  3B78 A;  4LF6 E;  4AIM A;  2UXD E;  2EFG A;  1ZM3 A;  1KKH A;  5LMU E;  1UEK A;  4OX9 E;  4OKG A;  4FW3 A;  3UHM A;  2JEA A;  2HKE A;  1HR0 I;  1N36 E;  3Q1Q A;  3JAM Q;  2F4V I;  5L3J A;  1IBM E;  2VQF E;  2C37 B;  3Q6M A;  4UTG A;  4OO1 C;  1N32 E;  5IT9 Q;  2ZM6 E;  2BA1 D;  1QZR A;  3J80 C;  4NXN I;  3M6A A;  5JEA D;  3B82 A;  1RR9 A;  2DEI A;  1XMO E;  5DNL A;  5K36 C;  1XNQ I;  1FJG E;  4DV2 I;  1XHK A;  5C0X D;  4DR4 I;  2Z5B B;  2O3Z A;  4BA1 A;  1N0V C;  5DRQ A;  2ZIT A;  3M85 D;  4DV6 I;  1NHJ A;  3PYE A;  1R6M A;  4N3O A;  4LFA I;  4MU0 A;  1B62 A;  2IOP A;  2UXC E;  2PO2 B;  4DXL A;  2CVE A;  4LCG A;  4P52 A;  3M85 G;  1XNR E;  3GON A;  2IOQ A;  4WUB A;  2HK3 A;  2UXB E;  1OJ4 A;  1USV A;  1H73 A;  4FW5 A;  4OO1 D;  4Z7Y A;  3PS3 A;  5A2Q Q;  3WU4 A;  3T1Y I;  2C39 A;  4JV5 I;  1N33 E;  3QT7 A;  4LF8 I;  4B3M I;  4LFC E;  4PRV A;  1I94 E;  2R42 A;  4U3B A;  4AQY I;  2V2Q A;  5K36 D;  3H4L A;  2NN6 F;  1IBL E;  2VF3 A;  4R1F A;  4JI2 I;  2GQ0 A;  2NN6 E;  2V34 A;  4DV7 I;  5DNX A;  4DUY I;  5C0X B;  4JI4 E;  1YH8 A;  1J5E E;  5FWK A;  4X66 E;  4NXM I;  2UU9 E;  1NHH A;  2CZ9 A;  4HYM A;  4JI8 I;  3PS1 A;  4YHH I;  4DV5 I;  2VQE E;  3J80 Q;  4YY3 E;  4X64 E;  4LF7 I;  2V2Z A;  4GKK E;  2C37 A;  2X36 A;  4DV3 E;  1E3P A;  4LFB I;  2JE6 A;  3PRY A;  1N34 I;  5IWA I;  2O1V A;  4IFD F;  2PNM A;  4DR1 E;  4IZJ A;  2WW4 A;  3LTO A;  4ED4 A; 
#chains in the Genus database with same CATH homology
 2AE8 A;  4LPF A;  4MU3 A;  2F1D A;  4MU4 A;  5EL9 A;  4MU1 A;  4LOM A;  4QNJ A;  5EKW A;  4QNK A;  4MU0 A;  5DNL A;  4GQU A;  5DNX A;  5ELW A;  1RHY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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