2GO3A

Crystal structure of aquifex aeolicus lpxc complexed with imidazole.
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 91
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go3A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go3A02
5DROA 4IS9A 5DRQA 4FW6A 3P3CA 4MQYA 4FW3A 1XXEA 3P3GA 4LCHA 2O3ZA 4U3DA 4U3BA 4LCFA 2IESA 3P3EA 4FW4A 1YHCA 3PS3A 4FW5A 4J3DA 3U1YA 4MDTA 2IERA 3P76A 3NZKA 1YH8A 2GO4A 5DRRA 2VESA 4ISAA 4FW7A 4LCGA 2GO3A 2JT2A 3PS1A 5DRPA 4OKGA 4OZEA 1P42A 3PS2A 2J65A 3UHMA
chains in the Genus database with same CATH superfamily
4N3OA 3QT5A 3JAMQ 3HULA 4DR6I 2CG9A 4LF4I 5BR8E 4DR5E 3K1JA 4HACB 1ELOA 1PKPA 4DV2E 2Q2EB 4K0KE 3ZKBA 4DR5I 5BR8I 2WP8B 5JEAF 1ZXNA 4MU0A 1MG7A 4FW7A 4DV2I 2WP8A 2JT2A 4DUZE 4K0KI 4Z7CA 5FWKA 1ZM9A 3T1YE 4DV1E 1XNRE 3UHMA 2HK2A 3B8HA 4DR4E 4FWGA 4DUZI 3QT8A 5C0XC 1I94E 4FW3A 3T1YI 4DV1I 1XNRI 2CZ9A 1KVKA 5K36E 4DR4I 5GMEA 4IFDB 1YHCA 4XTJA 1I94I 2UXBE 4IFDA 1YH8A 1B63A 2IOQA 1ZXMA 1VI7A 1Y5YA 5DRPA 4OZEA 2UXBI 2X7IA 4YHHE 2PNMA 1J5EE 1MU5A 2Z5BA 4IFDD 1U2RA 4JI1E 1PIEA 2PO1B 4USMA 2PO1A 2WW4A 4YHHI 5JEAE 4AIDA 1J5EI 4JI1I 2E5LE 4NXME 2HFUA 3PYDA 4WUBA 2HKJA 3M7ND 2NN6A 2O1WA 4P7AA 1OYRA 2E5LI 4NXMI 3M7NG 3JAMC 3J81Q 4JYAE 2NN6D 4MYTA 1B62A 1Z0GA 1A6FA 2WNRA 1HNXE 2ZBKB 5LL6R 4JYAI 3ZZUA 3WU4A 3GLLA 4URLA 4OO1B 4LF5E 5C0XB 1HNXI 5IT9Q 5JEAC 4Z7YA 4OO1A 2AJ4A 2IERA 3V5RA 2E1RA 1FJGE 4LF5I 3PRYA 1FKAE 1H72C 4M1KA 2J65A 2BV3A 1FJGI 4JI8E 2PNZA 4AQYE 3B82A 3PYEA 3ZKDA 2O3ZA 1BKNA 4JI8I 4AQYI 4DU7A 2BR2A 4PRXA 2Z5EA 4DPXA 2HHHE 3H4LA 4LFBI 4ZVIA 1NHHA 2CVEA 1Z5BA 4DPYA 1UDNA 4DPTA 2NN6E 5K36F 4X65E 4UTGA 3J7AM 2HHHI 4JI2E 1QZRA 2BA0D 4QNKA 1RREA 2ZITA 4FW6A 4X65I 1USUA 2BA0G 4JI2I 4MQYA 3GMEA 4FN5A 1UDOA 1OYSA 1KIJA 2VQFE 3J7AG 4R1FA 3LNUA 3J81C 4FW4A 4LFCE 3U1YA 4HACA 3P76A 3NZKA 2VQFI 2DEIA 1Y4SA 5IWAE 1IBLE 4X64E 4ISAA 5JEAB 4LFCI 4FWHA 1PVGA 1IBKE 4JI0E 1RR9A 2HKEA 4JI3E 2EFGA 3HJCA 5IWAI 3B4TA 4X64I 2O1VA 1IBLI 3D4JA 5IT9C 1DARA 3P3CA 3QT6A 1IBKI 4JI0I 1XXEA 4JI3I 1WUUA 2HFSA 2BM0A 4JI5E 1XHKA 2UUBE 1Z5CA 2UXCE 2X36A 1S4EA 5EL9A 4JI5I 4DXLA 3WU6A 2UUBI 2UXCI 2V2QA 3QT7A 4DV7E 4LF6E 1UDSA 1FI4A 3F0NA 3H1CA 1N34E 3J80Q 1KKHA 5DRQA 4LF7E 4DV3E 4DV7I 4LPFA 4IZKB 4LCHA 4LF6I 4IFDF 1N34I 4NBQA 4IZKA 1OYPA 4LF7I 4DV3I 3L7ZB 4PU9A 5K36C 1VISA 4DV0E 2JE6B 1XMOE 3L7ZA 1USVA 2JEBB 4LCGA 4EMDA 1H7UA 4DV6E 2JEBA 2O1TA 4BA2B 4DV0I 4JV5E 1XMOI 5DROA 4BA2A 4I3HA 1FWKA 4DV6I 4LF9E 2NN6F 2ZM6E 4JV5I 5LMUE 3WU3A 2IESA 2BA1D 2R3VA 4GKKE 3M6AA 2PNLA 4LOMA 2UU9E 4LF9I 4DV4E 2V2VA 5GMDA 2BA1G 4JI7I 4DUYE 1XNQE 2ZM6I 5C0XA 5LMUI 2VESA 1IBME 4JI4E 4GKKI 2UU9I 3Q6NA 4DV4I 1XNQI 2GS8A 1HNZE 4DUYI 4IFDE 4OO1D 5C0XD 4B3ME 5FLXQ 1IBMI 4JI4I 4UT4A 1Z0EA 1HNZI 4GKJE 3P3GA 4B3MI 3ZZTA 3K85A 1UEKA 4LFBE 3U1KA 1NHJA 3PS3A 3ZZ0A 1N36E 1ZM4A 2C39B 4GKJI 2NPFA 4DR2E 2OI2A 2GO4A 4JG4A 5EKWA 5ELWA 2V34A 3J80C 1N36I 3PS1A 5K36B 4DR2I 2VF3A 1FNMA 5A2QQ 2GQ0A 3GCMA 1D6TA 5LMNE 2IOPA 1E3PA 2BM1A 4IFDC 3DD6A 4DR1E 4DPUA 4DU8A 4MYUA 4DR7I 2F1DA 5LMNI 3P3EA 4LF8E 1ZM2A 1NHIA 2UXDE 4WUDA 4DR1I 1EI1A 1E3HA 1H7SA 3Q6MA 4LF8I 4OO1E 2UXDI 1Y60A 2A2DA 5JEAA 4IS9A 2NN6C 4NXNE 4JI6E 1Z0WA 4DPWA 1N0UA 5JEAD 4B3RE 5DNXA 1H73A 2A2CA 3WU5A 4NXNI 4JI6I 3M85D 4FW9A 1H74A 1Y4UA 3M85G 4MU1A 4B3RI 5FLXC 4B3SE 3KRNA 1RHYA 2PO2B 2PO0B 4FWDA 2GO3A 1HK7A 4OKGA 2PO0A 2PO2A 2XEXA 3B78A 4DR3E 4HYMA 4B3SI 3Q1QA 1XMQE 4OO1C 4PRVA 2Z5CB 2JEAB 4X66E 2F4VE 4DR3I 2JEAA 2Z5CA 2C37B 3CDJA 2V2ZA 2AE8A 1XMQI 4LCFA 1ZM3A 3PYGA 2C37A 4X66I 2LJPA 2F4VI 3OTOE 4FW5A 4AIMA 2V8PA 1Z0VA 4WUCA 5A2QC 1R6MA 4X62E 4HXZA 4OX9E 2Z5BB 1HNWE 3OTOI 4MU4A 5L3JA 2O1UA 1P42A 2JE6A 1Y6ZA 4X62I 4B3TE 4ED4A 1Z0CA 4OX9I 1HNWI 2UUAE 3CDIA 3PYFA 4BA1B 3CWVA 4KHPE 4U3BA 4BA1A 4JI7E 4B3TI 2NN6B 4DV5E 2UUAI 1R6LA 1FWLA 1Z0TA 4KQVA 4RPFA 4AM3A 1Z0BA 4KHPI 3GONA 3LTOA 4HY1A 4IZJB 4DV5I 1Z59A 1MX0A 2J7KA 4LFAE 2WNRB 3K17A 1KTVA 4IZJA 2R42A 4LFAI 3ZM7A 3V2UC 1K47A 1UDQA 4IZJD 1NZ0A 4U3DA 4OO1F 1N33E 5C0XF 2C38B 4J3DA 2VQEE 4MDTA 2C38A 1N33I 1Z5AA 2DEJA 2C39A 2VQEI 3T1HE 2CGEA 2PNZB 3PS2A 1N0VC 5K36A 4DR7E 1HR0E 3T1HI 2BR2B 1N32E 4QNJA 2UUCE 4P52A 5K36D 1EA6A 3LPSA 3P06A 4USKA 1HR0I 1N32I 2UUCI 4YY3E 1OJ4A 1S16A 5DRRA 4DR6E 4MU3A 2HK3A 4LF4E 3HKMA 5C0XE 5DNLA 4YY3I 4GQUA
chains in the Genus database with same CATH topology
5DROA 4IS9A 5DRQA 4FW6A 3P3CA 4MQYA 4FW3A 1XXEA 3P3GA 4LCHA 2O3ZA 4U3DA 4U3BA 4LCFA 2IESA 3P3EA 4FW4A 1YHCA 3PS3A 4FW5A 4J3DA 3U1YA 4MDTA 2IERA 3P76A 3NZKA 1YH8A 2GO4A 5DRRA 2VESA 4ISAA 4FW7A 4LCGA 2GO3A 2JT2A 3PS1A 5DRPA 4OKGA 4OZEA 1P42A 3PS2A 2J65A 3UHMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5DRO A;  4IS9 A;  5DRQ A;  4FW6 A;  3P3C A;  4MQY A;  4FW3 A;  1XXE A;  3P3G A;  4LCH A;  2O3Z A;  4U3D A;  4U3B A;  4LCF A;  2IES A;  3P3E A;  4FW4 A;  1YHC A;  3PS3 A;  4FW5 A;  4J3D A;  3U1Y A;  4MDT A;  2IER A;  3P76 A;  3NZK A;  1YH8 A;  2GO4 A;  5DRR A;  2VES A;  4ISA A;  4FW7 A;  4LCG A;  2GO3 A;  2JT2 A;  3PS1 A;  5DRP A;  4OKG A;  4OZE A;  1P42 A;  3PS2 A;  2J65 A;  3UHM A; 
#chains in the Genus database with same CATH topology
 4N3O A;  3QT5 A;  3JAM Q;  3HUL A;  4DR6 I;  2CG9 A;  4LF4 I;  5BR8 E;  4DR5 E;  3K1J A;  4HAC B;  1ELO A;  1PKP A;  4DV2 E;  2Q2E B;  4K0K E;  3ZKB A;  4DR5 I;  5BR8 I;  2WP8 B;  5JEA F;  1ZXN A;  4MU0 A;  1MG7 A;  4FW7 A;  4DV2 I;  2WP8 A;  2JT2 A;  4DUZ E;  4K0K I;  4Z7C A;  5FWK A;  1ZM9 A;  3T1Y E;  4DV1 E;  1XNR E;  3UHM A;  2HK2 A;  3B8H A;  4DR4 E;  4FWG A;  4DUZ I;  3QT8 A;  5C0X C;  1I94 E;  4FW3 A;  3T1Y I;  4DV1 I;  1XNR I;  2CZ9 A;  1KVK A;  5K36 E;  4DR4 I;  5GME A;  4IFD B;  1YHC A;  4XTJ A;  1I94 I;  2UXB E;  4IFD A;  1YH8 A;  1B63 A;  2IOQ A;  1ZXM A;  1VI7 A;  1Y5Y A;  5DRP A;  4OZE A;  2UXB I;  2X7I A;  4YHH E;  2PNM A;  1J5E E;  1MU5 A;  2Z5B A;  4IFD D;  1U2R A;  4JI1 E;  1PIE A;  2PO1 B;  4USM A;  2PO1 A;  2WW4 A;  4YHH I;  5JEA E;  4AID A;  1J5E I;  4JI1 I;  2E5L E;  4NXM E;  2HFU A;  3PYD A;  4WUB A;  2HKJ A;  3M7N D;  2NN6 A;  2O1W A;  4P7A A;  1OYR A;  2E5L I;  4NXM I;  3M7N G;  3JAM C;  3J81 Q;  4JYA E;  2NN6 D;  4MYT A;  1B62 A;  1Z0G A;  1A6F A;  2WNR A;  1HNX E;  2ZBK B;  5LL6 R;  4JYA I;  3ZZU A;  3WU4 A;  3GLL A;  4URL A;  4OO1 B;  4LF5 E;  5C0X B;  1HNX I;  5IT9 Q;  5JEA C;  4Z7Y A;  4OO1 A;  2AJ4 A;  2IER A;  3V5R A;  2E1R A;  1FJG E;  4LF5 I;  3PRY A;  1FKA E;  1H72 C;  4M1K A;  2J65 A;  2BV3 A;  1FJG I;  4JI8 E;  2PNZ A;  4AQY E;  3B82 A;  3PYE A;  3ZKD A;  2O3Z A;  1BKN A;  4JI8 I;  4AQY I;  4DU7 A;  2BR2 A;  4PRX A;  2Z5E A;  4DPX A;  2HHH E;  3H4L A;  4LFB I;  4ZVI A;  1NHH A;  2CVE A;  1Z5B A;  4DPY A;  1UDN A;  4DPT A;  2NN6 E;  5K36 F;  4X65 E;  4UTG A;  3J7A M;  2HHH I;  4JI2 E;  1QZR A;  2BA0 D;  4QNK A;  1RRE A;  2ZIT A;  4FW6 A;  4X65 I;  1USU A;  2BA0 G;  4JI2 I;  4MQY A;  3GME A;  4FN5 A;  1UDO A;  1OYS A;  1KIJ A;  2VQF E;  3J7A G;  4R1F A;  3LNU A;  3J81 C;  4FW4 A;  4LFC E;  3U1Y A;  4HAC A;  3P76 A;  3NZK A;  2VQF I;  2DEI A;  1Y4S A;  5IWA E;  1IBL E;  4X64 E;  4ISA A;  5JEA B;  4LFC I;  4FWH A;  1PVG A;  1IBK E;  4JI0 E;  1RR9 A;  2HKE A;  4JI3 E;  2EFG A;  3HJC A;  5IWA I;  3B4T A;  4X64 I;  2O1V A;  1IBL I;  3D4J A;  5IT9 C;  1DAR A;  3P3C A;  3QT6 A;  1IBK I;  4JI0 I;  1XXE A;  4JI3 I;  1WUU A;  2HFS A;  2BM0 A;  4JI5 E;  1XHK A;  2UUB E;  1Z5C A;  2UXC E;  2X36 A;  1S4E A;  5EL9 A;  4JI5 I;  4DXL A;  3WU6 A;  2UUB I;  2UXC I;  2V2Q A;  3QT7 A;  4DV7 E;  4LF6 E;  1UDS A;  1FI4 A;  3F0N A;  3H1C A;  1N34 E;  3J80 Q;  1KKH A;  5DRQ A;  4LF7 E;  4DV3 E;  4DV7 I;  4LPF A;  4IZK B;  4LCH A;  4LF6 I;  4IFD F;  1N34 I;  4NBQ A;  4IZK A;  1OYP A;  4LF7 I;  4DV3 I;  3L7Z B;  4PU9 A;  5K36 C;  1VIS A;  4DV0 E;  2JE6 B;  1XMO E;  3L7Z A;  1USV A;  2JEB B;  4LCG A;  4EMD A;  1H7U A;  4DV6 E;  2JEB A;  2O1T A;  4BA2 B;  4DV0 I;  4JV5 E;  1XMO I;  5DRO A;  4BA2 A;  4I3H A;  1FWK A;  4DV6 I;  4LF9 E;  2NN6 F;  2ZM6 E;  4JV5 I;  5LMU E;  3WU3 A;  2IES A;  2BA1 D;  2R3V A;  4GKK E;  3M6A A;  2PNL A;  4LOM A;  2UU9 E;  4LF9 I;  4DV4 E;  2V2V A;  5GMD A;  2BA1 G;  4JI7 I;  4DUY E;  1XNQ E;  2ZM6 I;  5C0X A;  5LMU I;  2VES A;  1IBM E;  4JI4 E;  4GKK I;  2UU9 I;  3Q6N A;  4DV4 I;  1XNQ I;  2GS8 A;  1HNZ E;  4DUY I;  4IFD E;  4OO1 D;  5C0X D;  4B3M E;  5FLX Q;  1IBM I;  4JI4 I;  4UT4 A;  1Z0E A;  1HNZ I;  4GKJ E;  3P3G A;  4B3M I;  3ZZT A;  3K85 A;  1UEK A;  4LFB E;  3U1K A;  1NHJ A;  3PS3 A;  3ZZ0 A;  1N36 E;  1ZM4 A;  2C39 B;  4GKJ I;  2NPF A;  4DR2 E;  2OI2 A;  2GO4 A;  4JG4 A;  5EKW A;  5ELW A;  2V34 A;  3J80 C;  1N36 I;  3PS1 A;  5K36 B;  4DR2 I;  2VF3 A;  1FNM A;  5A2Q Q;  2GQ0 A;  3GCM A;  1D6T A;  5LMN E;  2IOP A;  1E3P A;  2BM1 A;  4IFD C;  3DD6 A;  4DR1 E;  4DPU A;  4DU8 A;  4MYU A;  4DR7 I;  2F1D A;  5LMN I;  3P3E A;  4LF8 E;  1ZM2 A;  1NHI A;  2UXD E;  4WUD A;  4DR1 I;  1EI1 A;  1E3H A;  1H7S A;  3Q6M A;  4LF8 I;  4OO1 E;  2UXD I;  1Y60 A;  2A2D A;  5JEA A;  4IS9 A;  2NN6 C;  4NXN E;  4JI6 E;  1Z0W A;  4DPW A;  1N0U A;  5JEA D;  4B3R E;  5DNX A;  1H73 A;  2A2C A;  3WU5 A;  4NXN I;  4JI6 I;  3M85 D;  4FW9 A;  1H74 A;  1Y4U A;  3M85 G;  4MU1 A;  4B3R I;  5FLX C;  4B3S E;  3KRN A;  1RHY A;  2PO2 B;  2PO0 B;  4FWD A;  2GO3 A;  1HK7 A;  4OKG A;  2PO0 A;  2PO2 A;  2XEX A;  3B78 A;  4DR3 E;  4HYM A;  4B3S I;  3Q1Q A;  1XMQ E;  4OO1 C;  4PRV A;  2Z5C B;  2JEA B;  4X66 E;  2F4V E;  4DR3 I;  2JEA A;  2Z5C A;  2C37 B;  3CDJ A;  2V2Z A;  2AE8 A;  1XMQ I;  4LCF A;  1ZM3 A;  3PYG A;  2C37 A;  4X66 I;  2LJP A;  2F4V I;  3OTO E;  4FW5 A;  4AIM A;  2V8P A;  1Z0V A;  4WUC A;  5A2Q C;  1R6M A;  4X62 E;  4HXZ A;  4OX9 E;  2Z5B B;  1HNW E;  3OTO I;  4MU4 A;  5L3J A;  2O1U A;  1P42 A;  2JE6 A;  1Y6Z A;  4X62 I;  4B3T E;  4ED4 A;  1Z0C A;  4OX9 I;  1HNW I;  2UUA E;  3CDI A;  3PYF A;  4BA1 B;  3CWV A;  4KHP E;  4U3B A;  4BA1 A;  4JI7 E;  4B3T I;  2NN6 B;  4DV5 E;  2UUA I;  1R6L A;  1FWL A;  1Z0T A;  4KQV A;  4RPF A;  4AM3 A;  1Z0B A;  4KHP I;  3GON A;  3LTO A;  4HY1 A;  4IZJ B;  4DV5 I;  1Z59 A;  1MX0 A;  2J7K A;  4LFA E;  2WNR B;  3K17 A;  1KTV A;  4IZJ A;  2R42 A;  4LFA I;  3ZM7 A;  3V2U C;  1K47 A;  1UDQ A;  4IZJ D;  1NZ0 A;  4U3D A;  4OO1 F;  1N33 E;  5C0X F;  2C38 B;  4J3D A;  2VQE E;  4MDT A;  2C38 A;  1N33 I;  1Z5A A;  2DEJ A;  2C39 A;  2VQE I;  3T1H E;  2CGE A;  2PNZ B;  3PS2 A;  1N0V C;  5K36 A;  4DR7 E;  1HR0 E;  3T1H I;  2BR2 B;  1N32 E;  4QNJ A;  2UUC E;  4P52 A;  5K36 D;  1EA6 A;  3LPS A;  3P06 A;  4USK A;  1HR0 I;  1N32 I;  2UUC I;  4YY3 E;  1OJ4 A;  1S16 A;  5DRR A;  4DR6 E;  4MU3 A;  2HK3 A;  4LF4 E;  3HKM A;  5C0X E;  5DNL A;  4YY3 I;  4GQU A; 
#chains in the Genus database with same CATH homology
 5DRO A;  4IS9 A;  5DRQ A;  4FW6 A;  3P3C A;  4MQY A;  4FW3 A;  1XXE A;  3P3G A;  4LCH A;  2O3Z A;  4U3D A;  4U3B A;  4LCF A;  2IES A;  3P3E A;  4FW4 A;  1YHC A;  3PS3 A;  4FW5 A;  4J3D A;  3U1Y A;  4MDT A;  2IER A;  3P76 A;  3NZK A;  1YH8 A;  2GO4 A;  5DRR A;  2VES A;  4ISA A;  4FW7 A;  4LCG A;  2GO3 A;  2JT2 A;  3PS1 A;  5DRP A;  4OKG A;  4OZE A;  1P42 A;  3PS2 A;  2J65 A;  3UHM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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