2O3ZA

X-ray crystal structure of lpxc complexed with 3-heptyloxybenzoate
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC.
pubmed doi rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 91
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2o3zA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2o3zA02
1YHCA 1P42A 3U1YA 1YH8A 2IESA 4LCGA 2GO3A 4FW5A 3P3GA 3PS2A 4LCHA 2GO4A 2JT2A 3NZKA 5DROA 3UHMA 4U3BA 2J65A 4LCFA 4MQYA 4OZEA 5DRRA 2IERA 3P76A 5DRPA 4ISAA 4FW4A 4FW3A 2VESA 4J3DA 3PS3A 4MDTA 1XXEA 4FW7A 4FW6A 4IS9A 4OKGA 4U3DA 5DRQA 3P3CA 3PS1A 2O3ZA 3P3EA
chains in the Genus database with same CATH superfamily
1USVA 1H7UA 4LFAI 2PO2B 2V2ZA 4HYMA 2GO3A 2CZ9A 4GKKE 2UUBI 2NN6D 5IT9Q 5GMEA 5C0XF 2LJPA 1KVKA 4YY3E 2UU9E 4KHPE 4DV4I 2CG9A 1UDQA 1Z59A 1E3PA 1RHYA 3K1JA 4FW7A 5FWKA 5LMNE 4NXME 4HXZA 1UDNA 2UXDE 1IBMI 4B3TI 1Y4SA 4NBQA 2X7IA 2C38B 2BA1D 3L7ZA 2PO0B 5A2QC 4BA1B 4BA2B 4NXNI 2XEXA 3WU5A 3U1YA 1HNXI 2R42A 1ZM4A 2BM0A 2AJ4A 1BKNA 4FW5A 3B4TA 4JI7I 2NN6F 1HNWE 3T1HI 1Y4UA 3Q1QA 5C0XE 4X66E 4DV3I 1Z0VA 3LNUA 4WUCA 1PVGA 3B78A 4JI2E 4IS9A 1IBLI 1HK7A 1NHIA 1FWKA 3QT5A 2WNRB 1XMOE 4MU4A 5C0XA 2VQEI 4GQUA 1UEKA 3WU4A 3WU3A 2WP8B 2CGEA 1YH8A 2V34A 2E5LE 4LF6E 4LPFA 4WUBA 3T1HE 4JI0E 3KRNA 3J80Q 4FN5A 2GO4A 4IZJD 1D6TA 3ZZ0A 3GMEA 4LF7E 2NN6E 2HHHE 4LF9E 1OYRA 2PNZA 1IBLE 2HKEA 4MU3A 1N32I 1IBKI 4MU0A 4B3MI 4DUZE 1N34I 1FWLA 2NN6A 3PS1A 3LPSA 1NZ0A 1Z0CA 5LMUE 2E1RA 1YHCA 5EKWA 3GCMA 1MU5A 4EMDA 4LCGA 1FJGE 5K36C 4DR5I 1HNZE 3P3GA 4OX9I 4OO1F 1VI7A 2JT2A 1Z0BA 1N32E 2ZBKB 1ZM3A 2BM1A 4UTGA 1OJ4A 5DNLA 1USUA 2PNLA 1QZRA 2V8PA 1ZM2A 1N34E 1H7SA 3LTOA 2CVEA 4WUDA 2JEBB 4AIMA 2DEJA 4DPWA 4IZKA 2V2VA 3ZM7A 2O3ZA 2PO1B 4JI1I 4DR5E 4B3RE 1B62A 2ZM6E 4YHHI 2Z5CA 1MG7A 4JI4E 2VQFE 4X62I 2JEAB 5FLXC 1S4EA 1H72C 3OTOI 3H4LA 5JEAD 4MYUA 4OZEA 3QT8A 4DV7E 1XNRE 1N33I 3PYGA 2VESA 4R1FA 1Y5YA 4DV5E 4JI6E 1OYSA 3HULA 2UXCE 4OO1A 4K0KI 2C37B 4IZJA 3PRYA 3DD6A 3T1YE 2X36A 4DV0I 3ZKDA 2UUAE 4IFDD 4JYAE 4I3HA 4Z7CA 3GONA 4JI8I 2IOPA 2C39B 4RPFA 4DR7I 4X64E 5EL9A 1N36E 1E3HA 1XHKA 4FWHA 2NPFA 4PRXA 4GKJE 5JEAF 4MQYA 3CDIA 1DARA 4MYTA 5BR8E 4DV1I 4UT4A 4DV6E 3K17A 1XNQE 4LFAE 2A2DA 4IFDF 5IWAI 5C0XC 3B82A 2V2QA 2UUBE 5K36B 1HR0I 1R6MA 4DV4E 4LCFA 3V2UC 3ZZUA 4MU1A 4DR3I 5DRPA 4DPXA 5JEAE 4JI5I 1IBME 1U2RA 1XXEA 4FW6A 4OKGA 4B3TE 4U3DA 5DRQA 3P3CA 1NHHA 2NN6C 4NXNE 1HNXE 5JEAA 4P7AA 1RR9A 4AQYI 1P42A 4IFDE 4JI7E 3Q6NA 3M85G 2A2CA 4LCHA 4LF8I 4OO1D 1FKAE 4DV3E 4ED4A 4IFDA 4QNJA 4HACA 4B3SI 1Z5BA 3J81Q 4LFCI 1Y60A 3U1KA 1J5EI 2BV3A 1K47A 1OYPA 2VQEE 2JE6A 2PNMA 2BR2A 2UUCI 3L7ZB 3M6AA 2EFGA 3JAMC 3HJCA 3QT7A 4X65I 3PS2A 1KKHA 5DROA 5GMDA 4FWDA 1J5EE 3K85A 3PYDA 1IBKE 4B3ME 2F4VI 3Q6MA 4FW3A 4ZVIA 1EA6A 1N0UA 1KIJA 1PKPA 5C0XB 1I94I 2UXBI 4LF5I 2PO2A 3WU6A 4OX9E 1WUUA 4DR6I 4LF4I 4JI3I 1ELOA 2R3VA 4AIDA 3J7AM 2J65A 1KTVA 1R6LA 5IT9C 1FNMA 1PIEA 1S16A 4OO1E 4HY1A 2PNZB 4DPTA 5LL6R 2IERA 4LFBI 3P76A 4DV2I 2OI2A 4JV5I 1VISA 4DR1I 2NN6B 4JI1E 3B8HA 4DUYI 1H73A 3PYEA 4YHHE 1MX0A 4BA2A 4JI3E 2C38A 2PO0A 4X62E 4BA1A 4DR4I 4P52A 3OTOE 1NHJA 4DXLA 3J7AG 4USMA 4KQVA 1N33E 2HK3A 4GKKI 1RREA 1N0VC 1ZXNA 4DR1E 4FW4A 3PS3A 3V5RA 4DU8A 4YY3I 2UU9I 4K0KE 4KHPI 2DEIA 4IZKB 4DV0E 5LMNI 4Z7YA 4NXMI 2WNRA 4JI8E 4DR7E 2UXDI 5JEAC 5ELWA 4AM3A 2IOQA 2WP8A 2Z5CB 4DR2I 5FLXQ 1ZM9A 1Z0TA 3M85D 3J80C 1Z0WA 2HKJA 4DV1E 1HNWI 4IFDC 3J81C 3M7NG 4MDTA 4PU9A 2ZITA 4X66I 4OO1B 1XMQI 5IWAE 2GQ0A 1EI1A 4IZJB 4JI2I 2HK2A 3CWVA 2VF3A 4DR2E 3H1CA 3ZKBA 1XMOI 1HR0E 2O1TA 4USKA 4XTJA 1FI4A 4DR3E 2E5LI 4U3BA 4LF6I 4LOMA 4JI5E 4JI0I 4JG4A 2AE8A 5DNXA 1XMQE 4LF7I 2HHHI 4LF9I 4DPYA 5K36D 4URLA 2JEBA 2WW4A 2BA1G 4AQYE 4DUZI 3ZZTA 2PO1A 5A2QQ 5LMUI 4LF8E 2Q2EB 3F0NA 2Z5BA 2JEAA 4DU7A 3NZKA 3CDJA 1UDSA 2O1WA 3UHMA 4B3SE 1FJGI 1HNZI 4LFCE 1Y6ZA 4M1KA 1UDOA 2GS8A 1Z0GA 4ISAA 3HKMA 4J3DA 5K36F 1A6FA 2UUCE 2C37A 4OO1C 2F1DA 1Z0EA 4N3OA 3P3EA 5JEAB 3GLLA 3QT6A 4X65E 1H74A 2C39A 4B3RI 2ZM6I 2HFSA 2HFUA 4JI4I 2VQFI 2F4VE 4IFDB 4HACB 5DRRA 3P06A 4DV7I 1XNRI 1I94E 2JE6B 2UXBE 5K36E 4JI6I 4DV5I 2BA0D 4LF5E 2BR2B 4DR6E 2UXCI 3JAMQ 4LF4E 2J7KA 3T1YI 1ZXMA 2O1UA 4JYAI 2UUAI 4FW9A 2O1VA 2IESA 2Z5BB 1B63A 5K36A 3D4JA 4FWGA 4QNKA 2Z5EA 4PRVA 4X64I 3PYFA 4LFBE 5C0XD 1N36I 4DV2E 4JV5E 4GKJI 1Z5CA 5L3JA 2BA0G 4DUYE 5BR8I 4DPUA 3M7ND 1Z5AA 4DV6I 1XNQI 4DR4E
chains in the Genus database with same CATH topology
1YHCA 1P42A 3U1YA 1YH8A 2IESA 4LCGA 2GO3A 4FW5A 3P3GA 3PS2A 4LCHA 2GO4A 2JT2A 3NZKA 5DROA 3UHMA 4U3BA 2J65A 4LCFA 4MQYA 4OZEA 5DRRA 2IERA 3P76A 5DRPA 4ISAA 4FW4A 4FW3A 2VESA 4J3DA 3PS3A 4MDTA 1XXEA 4FW7A 4FW6A 4IS9A 4OKGA 4U3DA 5DRQA 3P3CA 3PS1A 2O3ZA 3P3EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YHC A;  1P42 A;  3U1Y A;  1YH8 A;  2IES A;  4LCG A;  2GO3 A;  4FW5 A;  3P3G A;  3PS2 A;  4LCH A;  2GO4 A;  2JT2 A;  3NZK A;  5DRO A;  3UHM A;  4U3B A;  2J65 A;  4LCF A;  4MQY A;  4OZE A;  5DRR A;  2IER A;  3P76 A;  5DRP A;  4ISA A;  4FW4 A;  4FW3 A;  2VES A;  4J3D A;  3PS3 A;  4MDT A;  1XXE A;  4FW7 A;  4FW6 A;  4IS9 A;  4OKG A;  4U3D A;  5DRQ A;  3P3C A;  3PS1 A;  2O3Z A;  3P3E A; 
#chains in the Genus database with same CATH topology
 1USV A;  1H7U A;  4LFA I;  2PO2 B;  2V2Z A;  4HYM A;  2GO3 A;  2CZ9 A;  4GKK E;  2UUB I;  2NN6 D;  5IT9 Q;  5GME A;  5C0X F;  2LJP A;  1KVK A;  4YY3 E;  2UU9 E;  4KHP E;  4DV4 I;  2CG9 A;  1UDQ A;  1Z59 A;  1E3P A;  1RHY A;  3K1J A;  4FW7 A;  5FWK A;  5LMN E;  4NXM E;  4HXZ A;  1UDN A;  2UXD E;  1IBM I;  4B3T I;  1Y4S A;  4NBQ A;  2X7I A;  2C38 B;  2BA1 D;  3L7Z A;  2PO0 B;  5A2Q C;  4BA1 B;  4BA2 B;  4NXN I;  2XEX A;  3WU5 A;  3U1Y A;  1HNX I;  2R42 A;  1ZM4 A;  2BM0 A;  2AJ4 A;  1BKN A;  4FW5 A;  3B4T A;  4JI7 I;  2NN6 F;  1HNW E;  3T1H I;  1Y4U A;  3Q1Q A;  5C0X E;  4X66 E;  4DV3 I;  1Z0V A;  3LNU A;  4WUC A;  1PVG A;  3B78 A;  4JI2 E;  4IS9 A;  1IBL I;  1HK7 A;  1NHI A;  1FWK A;  3QT5 A;  2WNR B;  1XMO E;  4MU4 A;  5C0X A;  2VQE I;  4GQU A;  1UEK A;  3WU4 A;  3WU3 A;  2WP8 B;  2CGE A;  1YH8 A;  2V34 A;  2E5L E;  4LF6 E;  4LPF A;  4WUB A;  3T1H E;  4JI0 E;  3KRN A;  3J80 Q;  4FN5 A;  2GO4 A;  4IZJ D;  1D6T A;  3ZZ0 A;  3GME A;  4LF7 E;  2NN6 E;  2HHH E;  4LF9 E;  1OYR A;  2PNZ A;  1IBL E;  2HKE A;  4MU3 A;  1N32 I;  1IBK I;  4MU0 A;  4B3M I;  4DUZ E;  1N34 I;  1FWL A;  2NN6 A;  3PS1 A;  3LPS A;  1NZ0 A;  1Z0C A;  5LMU E;  2E1R A;  1YHC A;  5EKW A;  3GCM A;  1MU5 A;  4EMD A;  4LCG A;  1FJG E;  5K36 C;  4DR5 I;  1HNZ E;  3P3G A;  4OX9 I;  4OO1 F;  1VI7 A;  2JT2 A;  1Z0B A;  1N32 E;  2ZBK B;  1ZM3 A;  2BM1 A;  4UTG A;  1OJ4 A;  5DNL A;  1USU A;  2PNL A;  1QZR A;  2V8P A;  1ZM2 A;  1N34 E;  1H7S A;  3LTO A;  2CVE A;  4WUD A;  2JEB B;  4AIM A;  2DEJ A;  4DPW A;  4IZK A;  2V2V A;  3ZM7 A;  2O3Z A;  2PO1 B;  4JI1 I;  4DR5 E;  4B3R E;  1B62 A;  2ZM6 E;  4YHH I;  2Z5C A;  1MG7 A;  4JI4 E;  2VQF E;  4X62 I;  2JEA B;  5FLX C;  1S4E A;  1H72 C;  3OTO I;  3H4L A;  5JEA D;  4MYU A;  4OZE A;  3QT8 A;  4DV7 E;  1XNR E;  1N33 I;  3PYG A;  2VES A;  4R1F A;  1Y5Y A;  4DV5 E;  4JI6 E;  1OYS A;  3HUL A;  2UXC E;  4OO1 A;  4K0K I;  2C37 B;  4IZJ A;  3PRY A;  3DD6 A;  3T1Y E;  2X36 A;  4DV0 I;  3ZKD A;  2UUA E;  4IFD D;  4JYA E;  4I3H A;  4Z7C A;  3GON A;  4JI8 I;  2IOP A;  2C39 B;  4RPF A;  4DR7 I;  4X64 E;  5EL9 A;  1N36 E;  1E3H A;  1XHK A;  4FWH A;  2NPF A;  4PRX A;  4GKJ E;  5JEA F;  4MQY A;  3CDI A;  1DAR A;  4MYT A;  5BR8 E;  4DV1 I;  4UT4 A;  4DV6 E;  3K17 A;  1XNQ E;  4LFA E;  2A2D A;  4IFD F;  5IWA I;  5C0X C;  3B82 A;  2V2Q A;  2UUB E;  5K36 B;  1HR0 I;  1R6M A;  4DV4 E;  4LCF A;  3V2U C;  3ZZU A;  4MU1 A;  4DR3 I;  5DRP A;  4DPX A;  5JEA E;  4JI5 I;  1IBM E;  1U2R A;  1XXE A;  4FW6 A;  4OKG A;  4B3T E;  4U3D A;  5DRQ A;  3P3C A;  1NHH A;  2NN6 C;  4NXN E;  1HNX E;  5JEA A;  4P7A A;  1RR9 A;  4AQY I;  1P42 A;  4IFD E;  4JI7 E;  3Q6N A;  3M85 G;  2A2C A;  4LCH A;  4LF8 I;  4OO1 D;  1FKA E;  4DV3 E;  4ED4 A;  4IFD A;  4QNJ A;  4HAC A;  4B3S I;  1Z5B A;  3J81 Q;  4LFC I;  1Y60 A;  3U1K A;  1J5E I;  2BV3 A;  1K47 A;  1OYP A;  2VQE E;  2JE6 A;  2PNM A;  2BR2 A;  2UUC I;  3L7Z B;  3M6A A;  2EFG A;  3JAM C;  3HJC A;  3QT7 A;  4X65 I;  3PS2 A;  1KKH A;  5DRO A;  5GMD A;  4FWD A;  1J5E E;  3K85 A;  3PYD A;  1IBK E;  4B3M E;  2F4V I;  3Q6M A;  4FW3 A;  4ZVI A;  1EA6 A;  1N0U A;  1KIJ A;  1PKP A;  5C0X B;  1I94 I;  2UXB I;  4LF5 I;  2PO2 A;  3WU6 A;  4OX9 E;  1WUU A;  4DR6 I;  4LF4 I;  4JI3 I;  1ELO A;  2R3V A;  4AID A;  3J7A M;  2J65 A;  1KTV A;  1R6L A;  5IT9 C;  1FNM A;  1PIE A;  1S16 A;  4OO1 E;  4HY1 A;  2PNZ B;  4DPT A;  5LL6 R;  2IER A;  4LFB I;  3P76 A;  4DV2 I;  2OI2 A;  4JV5 I;  1VIS A;  4DR1 I;  2NN6 B;  4JI1 E;  3B8H A;  4DUY I;  1H73 A;  3PYE A;  4YHH E;  1MX0 A;  4BA2 A;  4JI3 E;  2C38 A;  2PO0 A;  4X62 E;  4BA1 A;  4DR4 I;  4P52 A;  3OTO E;  1NHJ A;  4DXL A;  3J7A G;  4USM A;  4KQV A;  1N33 E;  2HK3 A;  4GKK I;  1RRE A;  1N0V C;  1ZXN A;  4DR1 E;  4FW4 A;  3PS3 A;  3V5R A;  4DU8 A;  4YY3 I;  2UU9 I;  4K0K E;  4KHP I;  2DEI A;  4IZK B;  4DV0 E;  5LMN I;  4Z7Y A;  4NXM I;  2WNR A;  4JI8 E;  4DR7 E;  2UXD I;  5JEA C;  5ELW A;  4AM3 A;  2IOQ A;  2WP8 A;  2Z5C B;  4DR2 I;  5FLX Q;  1ZM9 A;  1Z0T A;  3M85 D;  3J80 C;  1Z0W A;  2HKJ A;  4DV1 E;  1HNW I;  4IFD C;  3J81 C;  3M7N G;  4MDT A;  4PU9 A;  2ZIT A;  4X66 I;  4OO1 B;  1XMQ I;  5IWA E;  2GQ0 A;  1EI1 A;  4IZJ B;  4JI2 I;  2HK2 A;  3CWV A;  2VF3 A;  4DR2 E;  3H1C A;  3ZKB A;  1XMO I;  1HR0 E;  2O1T A;  4USK A;  4XTJ A;  1FI4 A;  4DR3 E;  2E5L I;  4U3B A;  4LF6 I;  4LOM A;  4JI5 E;  4JI0 I;  4JG4 A;  2AE8 A;  5DNX A;  1XMQ E;  4LF7 I;  2HHH I;  4LF9 I;  4DPY A;  5K36 D;  4URL A;  2JEB A;  2WW4 A;  2BA1 G;  4AQY E;  4DUZ I;  3ZZT A;  2PO1 A;  5A2Q Q;  5LMU I;  4LF8 E;  2Q2E B;  3F0N A;  2Z5B A;  2JEA A;  4DU7 A;  3NZK A;  3CDJ A;  1UDS A;  2O1W A;  3UHM A;  4B3S E;  1FJG I;  1HNZ I;  4LFC E;  1Y6Z A;  4M1K A;  1UDO A;  2GS8 A;  1Z0G A;  4ISA A;  3HKM A;  4J3D A;  5K36 F;  1A6F A;  2UUC E;  2C37 A;  4OO1 C;  2F1D A;  1Z0E A;  4N3O A;  3P3E A;  5JEA B;  3GLL A;  3QT6 A;  4X65 E;  1H74 A;  2C39 A;  4B3R I;  2ZM6 I;  2HFS A;  2HFU A;  4JI4 I;  2VQF I;  2F4V E;  4IFD B;  4HAC B;  5DRR A;  3P06 A;  4DV7 I;  1XNR I;  1I94 E;  2JE6 B;  2UXB E;  5K36 E;  4JI6 I;  4DV5 I;  2BA0 D;  4LF5 E;  2BR2 B;  4DR6 E;  2UXC I;  3JAM Q;  4LF4 E;  2J7K A;  3T1Y I;  1ZXM A;  2O1U A;  4JYA I;  2UUA I;  4FW9 A;  2O1V A;  2IES A;  2Z5B B;  1B63 A;  5K36 A;  3D4J A;  4FWG A;  4QNK A;  2Z5E A;  4PRV A;  4X64 I;  3PYF A;  4LFB E;  5C0X D;  1N36 I;  4DV2 E;  4JV5 E;  4GKJ I;  1Z5C A;  5L3J A;  2BA0 G;  4DUY E;  5BR8 I;  4DPU A;  3M7N D;  1Z5A A;  4DV6 I;  1XNQ I;  4DR4 E; 
#chains in the Genus database with same CATH homology
 1YHC A;  1P42 A;  3U1Y A;  1YH8 A;  2IES A;  4LCG A;  2GO3 A;  4FW5 A;  3P3G A;  3PS2 A;  4LCH A;  2GO4 A;  2JT2 A;  3NZK A;  5DRO A;  3UHM A;  4U3B A;  2J65 A;  4LCF A;  4MQY A;  4OZE A;  5DRR A;  2IER A;  3P76 A;  5DRP A;  4ISA A;  4FW4 A;  4FW3 A;  2VES A;  4J3D A;  3PS3 A;  4MDT A;  1XXE A;  4FW7 A;  4FW6 A;  4IS9 A;  4OKG A;  4U3D A;  5DRQ A;  3P3C A;  3PS1 A;  2O3Z A;  3P3E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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