2F1DA

X-ray structure of imidazoleglycerol-phosphate dehydratase
Total Genus 54
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
54
sequence length
183
structure length
183
Chain Sequence
GRIGEVKRVTKETNVSVKINLDGTGVADSSSGIPFLDHMLDQLASHGLFDVHVRATGDVHIDDHHTNEDIALAIGTALLKALGERKGINRFGDFTAPLDEALIHVSLDLSGRPYLGYNLEIPTQRVGTYDTQLVEHFFQSLVNTSGMTLHIRQLAGENSHHIIEATFKAFARALRQATETDPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of imidazoleglycerol-phosphate dehydratase.
pubmed doi rcsb
molecule tags Lyase
source organism Arabidopsis thaliana
molecule keywords Imidazoleglycerol-phosphate dehydratase 1
total genus 54
structure length 183
sequence length 183
chains with identical sequence B, C, D, E, F, G, H, I, J, K, L, M, N, O, P
ec nomenclature ec 4.2.1.19: Imidazoleglycerol-phosphate dehydratase.
pdb deposition date 2005-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00475 IGPD Imidazoleglycerol-phosphate dehydratase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 2f1dA01
3.30.230.40 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 Imidazole glycerol phosphate dehydratase; domain 1 2f1dA02
4MU3A 4QNKA 1RHYA 5EL9A 5ELWA 4LOMA 4MU1A 2F1DA 4LPFA 5DNLA 2AE8A 4GQUA 5DNXA 4QNJA 4MU4A 4MU0A 5EKWA
chains in the Genus database with same CATH superfamily
3ZKBA 3D4JA 2WP8A 3P06A 4LF4E 5IT9Q 1MX0A 4FWGA 4X64E 1S4EA 2F1DA 4DR2I 1ZM4A 4DV1I 4DR1E 5DRPA 4LFBE 4OZEA 3M85D 4MU1A 2A2DA 2C38A 2V8PA 3LPSA 4DV6I 4LF7I 4DV3I 1HK7A 4DV0E 4USKA 2ZITA 1N32I 2CGEA 4FW3A 2BA0G 5JEAC 3M7NG 3T1HE 4LF8E 1UDQA 3WU6A 4HACB 4DR7E 4N3OA 1EA6A 3GMEA 4DPWA 5C0XF 3F0NA 1HNZI 1KVKA 2J65A 1XHKA 1Z0EA 1N36E 3OTOE 1FWLA 4LF6I 4WUCA 4NXME 1QZRA 1IBMI 2R3VA 2GO3A 3B8HA 3QT5A 3J81Q 5C0XE 2HFSA 2VQEE 2V2QA 4M1KA 4JI1E 5FWKA 3ZKDA 3ZM7A 4JI5I 2BA1G 1ELOA 1Z0TA 3ZZTA 4PRVA 2HHHI 1USUA 4DV4I 1K47A 4K0KE 2UU9I 4LPFA 4AQYI 4FN5A 4DV5E 4X62E 4OX9E 1USVA 5DROA 1N33I 3JAMC 4DXLA 2R42A 1S16A 5FLXC 3P76A 4LF5I 4IFDD 3Q6MA 5JEAB 4RPFA 1FJGI 4JI3E 2GS8A 4OO1D 3Q6NA 4B3RI 4DV2E 3J7AM 1Z59A 5ELWA 2V2VA 4B3ME 4ZVIA 4JI0E 1OYSA 3L7ZB 2LJPA 4UTGA 2C37A 4LFAE 4JI8E 4MYUA 1Z0BA 2IESA 4IZJB 1RR9A 2UUBI 4Z7YA 4ED4A 2E5LE 2VESA 1N36I 1I94I 2UXDI 1EI1A 4EMDA 1KIJA 1NHIA 2JEBA 5IWAE 2UXCI 5LMUI 4J3DA 4B3SI 4DR4I 1BKNA 1VISA 1NHHA 4GKJI 4X66E 3UHMA 4YHHI 1XNQE 5A2QC 4X65I 1J5EI 3P3CA 4HACA 1WUUA 2JE6A 2C37B 3B78A 1MU5A 2UUCI 2HKJA 4IFDC 5GMDA 2ZM6I 4YY3E 3QT8A 4LF9E 1OYPA 3V5RA 2VQFI 1UDNA 4OO1C 2C39A 1A6FA 5K36E 3HULA 4JG4A 4KHPI 2NN6D 2V2ZA 3Q1QA 2UXBE 4B3TE 2CZ9A 3CDIA 5DNLA 5IT9C 2JEBB 1Z0CA 4AM3A 1XMQI 2Z5CA 2O1VA 3H4LA 3LNUA 2X36A 4DR3I 4MU4A 1H7SA 2AJ4A 1XMOE 5EL9A 4NXNE 2JE6B 4IS9A 4IFDA 2Z5EA 1B62A 3T1YE 2F4VE 3HKMA 2IERA 1N34I 1OJ4A 1VI7A 4IZKA 4OO1A 4JI7E 1FKAE 1HR0I 1IBKI 2J7KA 5BR8I 2BR2A 2C39B 1HNXI 2E5LI 4JI4I 1XNRE 4HXZA 5JEAF 2CVEA 5LMNI 4JI2E 4DR6I 4AIMA 4DUYE 4HYMA 2Z5CB 5JEAA 1E3PA 2PO2A 4DR5I 4JYAE 2UUAI 2PO0A 4MU3A 3J81C 4IFDB 1E3HA 1Z0VA 4BA2A 4FW7A 4QNJA 4XTJA 4I3HA 4JI6E 5EKWA 2NN6C 4DV7I 3L7ZA 3PS1A 4OO1B 4IZKB 5K36D 4DU7A 2HK3A 1YH8A 2A2CA 2BR2B 4FW6A 4IZJA 4LF4I 4LF9I 4U3BA 4X64I 3PS3A 4JV5E 4DR1I 4LFBI 4LFCE 4MQYA 4LCGA 4DPTA 5GMEA 1UEKA 1H7UA 3CDJA 2PO2B 4DV0I 2PO0B 1ZXMA 5FLXQ 1YHCA 4BA2B 2NN6A 4P7AA 3M85G 3T1HI 4LF8I 2JEAB 3K85A 4DR7I 1XXEA 4NXNI 4DR2E 4DV1E 1Y4SA 3B82A 3WU4A 1B63A 4MYTA 3PYDA 3T1YI 3WU5A 1HNWE 2X7IA 3NZKA 4AIDA 4DV6E 2EFGA 4LF7E 4FW4A 4DV3E 4P52A 3HJCA 2BM1A 1N32E 3OTOI 3KRNA 1RHYA 1Z5AA 5C0XD 4NXMI 1IBLE 2O3ZA 2PNMA 4USMA 3QT7A 5K36C 1Z0GA 2VQEI 2NN6B 5DRRA 4JI1I 3P3EA 4DU8A 1NZ0A 4UT4A 4LF6E 2VF3A 3J80C 1IBME 4K0KI 2WNRA 4MDTA 4R1FA 1ZM9A 4GKKE 2AE8A 4DV5I 2ZBKB 4X62I 4OX9I 2PNZA 4LCHA 4OKGA 4FW5A 3P3GA 3DD6A 4GQUA 4JI5E 2O1TA 3PYFA 2DEJA 2HHHE 1H72C 1U2RA 2E1RA 3CWVA 2HKEA 4DV4E 4JI3I 1FI4A 2UU9E 1RREA 4IFDF 4AQYE 4DV2I 3PRYA 2GO4A 1Z0WA 4B3MI 1H74A 3M6AA 4OO1F 1N33E 4JI0I 2WNRB 5C0XC 4LF5E 1Y60A 4LFAI 4JI8I 2HFUA 4HY1A 1HNWI 1FJGE 1Z5BA 1H73A 3J7AG 1UDOA 2PNZB 4IFDE 4B3RE 1ZM2A 4DUZE 3QT6A 4WUDA 1OYRA 2GQ0A 2BV3A 5K36B 1PIEA 4OO1E 1IBLI 5IWAI 4DPYA 4FWHA 1PVGA 1MG7A 2WP8B 3GLLA 2V34A 2UUBE 1N0UA 2PO1A 4X66I 5C0XA 1XNQI 1I94E 3U1YA 2UXDE 1ZXNA 2JEAA 5JEAE 2PNLA 2IOQA 2DEIA 1R6LA 2C38B 5L3JA 3PYGA 3PYEA 4YY3I 4GKKI 2UXCE 1N0VC 5LMUE 4ISAA 4B3SE 4DR4E 1ZM3A 4GKJE 2UXBI 4YHHE 2IOPA 3K17A 4B3TI 3U1KA 4X65E 1J5EE 2UUCE 2O1UA 2NN6F 4FWDA 4PRXA 2Q2EB 4DPUA 3JAMQ 2ZM6E 2PO1B 2CG9A 3V2UC 5C0XB 1XMOI 2OI2A 1FNMA 3GONA 4MU0A 2VQFE 4QNKA 3PS2A 4NBQA 4KHPE 1Y4UA 3ZZUA 2BA0D 3M7ND 2NPFA 4U3DA 2F4VI 4KQVA 4JI7I 1XMQE 1PKPA 2NN6E 2O1WA 2Z5BA 4DR3E 1UDSA 2XEXA 1KTVA 3B4TA 1KKHA 4DUZI 1XNRI 1Z5CA 1P42A 4JI2I 3WU3A 4Z7CA 2BM0A 4DUYI 5DNXA 4BA1A 1DARA 5LL6R 1N34E 1HNZE 1HR0E 3LTOA 2HK2A 1IBKE 4JYAI 5JEAD 5BR8E 1Y6ZA 3K1JA 1HNXE 4JI4E 1D6TA 1FWKA 4JI6I 5LMNE 4DR6E 2JT2A 4PU9A 4DPXA 2BA1D 4LOMA 5DRQA 4URLA 2Z5BB 5A2QQ 4FW9A 4LCFA 2WW4A 4WUBA 4DR5E 2UUAE 5K36F 1Y5YA 3J80Q 4IZJD 1R6MA 4JV5I 4LFCI 3GCMA 1NHJA 5K36A 3H1CA 3ZZ0A 4BA1B 4DV7E
chains in the Genus database with same CATH topology
4MU3A 4QNKA 1RHYA 5EL9A 5ELWA 4LOMA 4MU1A 2F1DA 4LPFA 5DNLA 2AE8A 4GQUA 5DNXA 4QNJA 4MU4A 4MU0A 5EKWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4MU3 A;  4QNK A;  1RHY A;  5EL9 A;  5ELW A;  4LOM A;  4MU1 A;  2F1D A;  4LPF A;  5DNL A;  2AE8 A;  4GQU A;  5DNX A;  4QNJ A;  4MU4 A;  4MU0 A;  5EKW A; 
#chains in the Genus database with same CATH topology
 3ZKB A;  3D4J A;  2WP8 A;  3P06 A;  4LF4 E;  5IT9 Q;  1MX0 A;  4FWG A;  4X64 E;  1S4E A;  2F1D A;  4DR2 I;  1ZM4 A;  4DV1 I;  4DR1 E;  5DRP A;  4LFB E;  4OZE A;  3M85 D;  4MU1 A;  2A2D A;  2C38 A;  2V8P A;  3LPS A;  4DV6 I;  4LF7 I;  4DV3 I;  1HK7 A;  4DV0 E;  4USK A;  2ZIT A;  1N32 I;  2CGE A;  4FW3 A;  2BA0 G;  5JEA C;  3M7N G;  3T1H E;  4LF8 E;  1UDQ A;  3WU6 A;  4HAC B;  4DR7 E;  4N3O A;  1EA6 A;  3GME A;  4DPW A;  5C0X F;  3F0N A;  1HNZ I;  1KVK A;  2J65 A;  1XHK A;  1Z0E A;  1N36 E;  3OTO E;  1FWL A;  4LF6 I;  4WUC A;  4NXM E;  1QZR A;  1IBM I;  2R3V A;  2GO3 A;  3B8H A;  3QT5 A;  3J81 Q;  5C0X E;  2HFS A;  2VQE E;  2V2Q A;  4M1K A;  4JI1 E;  5FWK A;  3ZKD A;  3ZM7 A;  4JI5 I;  2BA1 G;  1ELO A;  1Z0T A;  3ZZT A;  4PRV A;  2HHH I;  1USU A;  4DV4 I;  1K47 A;  4K0K E;  2UU9 I;  4LPF A;  4AQY I;  4FN5 A;  4DV5 E;  4X62 E;  4OX9 E;  1USV A;  5DRO A;  1N33 I;  3JAM C;  4DXL A;  2R42 A;  1S16 A;  5FLX C;  3P76 A;  4LF5 I;  4IFD D;  3Q6M A;  5JEA B;  4RPF A;  1FJG I;  4JI3 E;  2GS8 A;  4OO1 D;  3Q6N A;  4B3R I;  4DV2 E;  3J7A M;  1Z59 A;  5ELW A;  2V2V A;  4B3M E;  4ZVI A;  4JI0 E;  1OYS A;  3L7Z B;  2LJP A;  4UTG A;  2C37 A;  4LFA E;  4JI8 E;  4MYU A;  1Z0B A;  2IES A;  4IZJ B;  1RR9 A;  2UUB I;  4Z7Y A;  4ED4 A;  2E5L E;  2VES A;  1N36 I;  1I94 I;  2UXD I;  1EI1 A;  4EMD A;  1KIJ A;  1NHI A;  2JEB A;  5IWA E;  2UXC I;  5LMU I;  4J3D A;  4B3S I;  4DR4 I;  1BKN A;  1VIS A;  1NHH A;  4GKJ I;  4X66 E;  3UHM A;  4YHH I;  1XNQ E;  5A2Q C;  4X65 I;  1J5E I;  3P3C A;  4HAC A;  1WUU A;  2JE6 A;  2C37 B;  3B78 A;  1MU5 A;  2UUC I;  2HKJ A;  4IFD C;  5GMD A;  2ZM6 I;  4YY3 E;  3QT8 A;  4LF9 E;  1OYP A;  3V5R A;  2VQF I;  1UDN A;  4OO1 C;  2C39 A;  1A6F A;  5K36 E;  3HUL A;  4JG4 A;  4KHP I;  2NN6 D;  2V2Z A;  3Q1Q A;  2UXB E;  4B3T E;  2CZ9 A;  3CDI A;  5DNL A;  5IT9 C;  2JEB B;  1Z0C A;  4AM3 A;  1XMQ I;  2Z5C A;  2O1V A;  3H4L A;  3LNU A;  2X36 A;  4DR3 I;  4MU4 A;  1H7S A;  2AJ4 A;  1XMO E;  5EL9 A;  4NXN E;  2JE6 B;  4IS9 A;  4IFD A;  2Z5E A;  1B62 A;  3T1Y E;  2F4V E;  3HKM A;  2IER A;  1N34 I;  1OJ4 A;  1VI7 A;  4IZK A;  4OO1 A;  4JI7 E;  1FKA E;  1HR0 I;  1IBK I;  2J7K A;  5BR8 I;  2BR2 A;  2C39 B;  1HNX I;  2E5L I;  4JI4 I;  1XNR E;  4HXZ A;  5JEA F;  2CVE A;  5LMN I;  4JI2 E;  4DR6 I;  4AIM A;  4DUY E;  4HYM A;  2Z5C B;  5JEA A;  1E3P A;  2PO2 A;  4DR5 I;  4JYA E;  2UUA I;  2PO0 A;  4MU3 A;  3J81 C;  4IFD B;  1E3H A;  1Z0V A;  4BA2 A;  4FW7 A;  4QNJ A;  4XTJ A;  4I3H A;  4JI6 E;  5EKW A;  2NN6 C;  4DV7 I;  3L7Z A;  3PS1 A;  4OO1 B;  4IZK B;  5K36 D;  4DU7 A;  2HK3 A;  1YH8 A;  2A2C A;  2BR2 B;  4FW6 A;  4IZJ A;  4LF4 I;  4LF9 I;  4U3B A;  4X64 I;  3PS3 A;  4JV5 E;  4DR1 I;  4LFB I;  4LFC E;  4MQY A;  4LCG A;  4DPT A;  5GME A;  1UEK A;  1H7U A;  3CDJ A;  2PO2 B;  4DV0 I;  2PO0 B;  1ZXM A;  5FLX Q;  1YHC A;  4BA2 B;  2NN6 A;  4P7A A;  3M85 G;  3T1H I;  4LF8 I;  2JEA B;  3K85 A;  4DR7 I;  1XXE A;  4NXN I;  4DR2 E;  4DV1 E;  1Y4S A;  3B82 A;  3WU4 A;  1B63 A;  4MYT A;  3PYD A;  3T1Y I;  3WU5 A;  1HNW E;  2X7I A;  3NZK A;  4AID A;  4DV6 E;  2EFG A;  4LF7 E;  4FW4 A;  4DV3 E;  4P52 A;  3HJC A;  2BM1 A;  1N32 E;  3OTO I;  3KRN A;  1RHY A;  1Z5A A;  5C0X D;  4NXM I;  1IBL E;  2O3Z A;  2PNM A;  4USM A;  3QT7 A;  5K36 C;  1Z0G A;  2VQE I;  2NN6 B;  5DRR A;  4JI1 I;  3P3E A;  4DU8 A;  1NZ0 A;  4UT4 A;  4LF6 E;  2VF3 A;  3J80 C;  1IBM E;  4K0K I;  2WNR A;  4MDT A;  4R1F A;  1ZM9 A;  4GKK E;  2AE8 A;  4DV5 I;  2ZBK B;  4X62 I;  4OX9 I;  2PNZ A;  4LCH A;  4OKG A;  4FW5 A;  3P3G A;  3DD6 A;  4GQU A;  4JI5 E;  2O1T A;  3PYF A;  2DEJ A;  2HHH E;  1H72 C;  1U2R A;  2E1R A;  3CWV A;  2HKE A;  4DV4 E;  4JI3 I;  1FI4 A;  2UU9 E;  1RRE A;  4IFD F;  4AQY E;  4DV2 I;  3PRY A;  2GO4 A;  1Z0W A;  4B3M I;  1H74 A;  3M6A A;  4OO1 F;  1N33 E;  4JI0 I;  2WNR B;  5C0X C;  4LF5 E;  1Y60 A;  4LFA I;  4JI8 I;  2HFU A;  4HY1 A;  1HNW I;  1FJG E;  1Z5B A;  1H73 A;  3J7A G;  1UDO A;  2PNZ B;  4IFD E;  4B3R E;  1ZM2 A;  4DUZ E;  3QT6 A;  4WUD A;  1OYR A;  2GQ0 A;  2BV3 A;  5K36 B;  1PIE A;  4OO1 E;  1IBL I;  5IWA I;  4DPY A;  4FWH A;  1PVG A;  1MG7 A;  2WP8 B;  3GLL A;  2V34 A;  2UUB E;  1N0U A;  2PO1 A;  4X66 I;  5C0X A;  1XNQ I;  1I94 E;  3U1Y A;  2UXD E;  1ZXN A;  2JEA A;  5JEA E;  2PNL A;  2IOQ A;  2DEI A;  1R6L A;  2C38 B;  5L3J A;  3PYG A;  3PYE A;  4YY3 I;  4GKK I;  2UXC E;  1N0V C;  5LMU E;  4ISA A;  4B3S E;  4DR4 E;  1ZM3 A;  4GKJ E;  2UXB I;  4YHH E;  2IOP A;  3K17 A;  4B3T I;  3U1K A;  4X65 E;  1J5E E;  2UUC E;  2O1U A;  2NN6 F;  4FWD A;  4PRX A;  2Q2E B;  4DPU A;  3JAM Q;  2ZM6 E;  2PO1 B;  2CG9 A;  3V2U C;  5C0X B;  1XMO I;  2OI2 A;  1FNM A;  3GON A;  4MU0 A;  2VQF E;  4QNK A;  3PS2 A;  4NBQ A;  4KHP E;  1Y4U A;  3ZZU A;  2BA0 D;  3M7N D;  2NPF A;  4U3D A;  2F4V I;  4KQV A;  4JI7 I;  1XMQ E;  1PKP A;  2NN6 E;  2O1W A;  2Z5B A;  4DR3 E;  1UDS A;  2XEX A;  1KTV A;  3B4T A;  1KKH A;  4DUZ I;  1XNR I;  1Z5C A;  1P42 A;  4JI2 I;  3WU3 A;  4Z7C A;  2BM0 A;  4DUY I;  5DNX A;  4BA1 A;  1DAR A;  5LL6 R;  1N34 E;  1HNZ E;  1HR0 E;  3LTO A;  2HK2 A;  1IBK E;  4JYA I;  5JEA D;  5BR8 E;  1Y6Z A;  3K1J A;  1HNX E;  4JI4 E;  1D6T A;  1FWK A;  4JI6 I;  5LMN E;  4DR6 E;  2JT2 A;  4PU9 A;  4DPX A;  2BA1 D;  4LOM A;  5DRQ A;  4URL A;  2Z5B B;  5A2Q Q;  4FW9 A;  4LCF A;  2WW4 A;  4WUB A;  4DR5 E;  2UUA E;  5K36 F;  1Y5Y A;  3J80 Q;  4IZJ D;  1R6M A;  4JV5 I;  4LFC I;  3GCM A;  1NHJ A;  5K36 A;  3H1C A;  3ZZ0 A;  4BA1 B;  4DV7 E; 
#chains in the Genus database with same CATH homology
 4MU3 A;  4QNK A;  1RHY A;  5EL9 A;  5ELW A;  4LOM A;  4MU1 A;  2F1D A;  4LPF A;  5DNL A;  2AE8 A;  4GQU A;  5DNX A;  4QNJ A;  4MU4 A;  4MU0 A;  5EKW A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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