2GO4A

Crystal structure of aquifex aeolicus lpxc complexed with tu-514
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
266
structure length
266
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic Inferences from the Binding of Ligands to LpxC, a Metal-Dependent Deacetylase
pubmed doi rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 88
structure length 266
sequence length 266
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2go4A01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2go4A02
2J65A 3PS3A 4U3DA 2IERA 3UHMA 3PS2A 4J3DA 4MDTA 4FW3A 4LCFA 1P42A 2O3ZA 5DRQA 3P3CA 5DRPA 4FW4A 4FW7A 3P3GA 4OKGA 3P76A 1YH8A 4OZEA 2IESA 3NZKA 5DROA 4IS9A 4FW6A 2GO4A 2VESA 3PS1A 2GO3A 4FW5A 1YHCA 4MQYA 4U3BA 3U1YA 5DRRA 3P3EA 4ISAA 2JT2A 4LCHA 4LCGA 1XXEA
chains in the Genus database with same CATH superfamily
1ZM4A 2J7KA 3UHMA 2ZM6E 2AE8A 4B3SI 4AIDA 3GLLA 4FW4A 3T1HI 1XNQE 4P7AA 1Y5YA 4IFDC 4Z7YA 4DV7I 1YH8A 3F0NA 4MU3A 1H73A 4DV6E 1I94E 4IZJB 4X65E 2XEXA 4IFDB 3HKMA 5BR8I 2CZ9A 4B3SE 4X62I 1ZXNA 1H7UA 1Z0VA 1USVA 3T1HE 1K47A 4YHHI 4X64I 2WNRA 5C0XC 4LCFA 4DV2I 3K85A 5GMDA 4FW7A 5IT9C 1FNMA 4IZKB 2A2CA 1HNXI 5BR8E 5LL6R 4PRXA 5JEAD 5C0XB 4X62E 4JV5I 2BA1D 2R3VA 4R1FA 4YHHE 4X64E 4MYUA 1Z5AA 4DV2E 4EMDA 3PYGA 4USKA 4DPUA 3PS2A 1IBLI 2Z5CB 1XHKA 2VQEI 2BM0A 4LF6I 4FWHA 4YY3I 1HNXE 1NHIA 3QT6A 5DRQA 4JI6I 1N36I 5K36A 2VQFI 1OYSA 4JV5E 5IT9Q 3B4TA 1Y4SA 1Z59A 3B8HA 4WUBA 2PO0A 4NBQA 5JEAA 4FN5A 3U1YA 2NN6F 3QT5A 1IBLE 2VQEE 4M1KA 2UUBI 2C39A 3J80Q 4YY3E 4LF6E 2LJPA 2WP8A 1UDOA 1XNRI 4WUDA 4JI6E 1N36E 2E5LI 2VQFE 1XMOI 4ED4A 4LF5I 4N3OA 4QNKA 2UXCI 2CVEA 5EL9A 4LF7I 4LFCI 5L3JA 2BA0G 4LPFA 1EI1A 2O1UA 1ZM9A 4DV4I 2GS8A 3LNUA 1USUA 1NHHA 2X36A 2UUBE 4B3MI 1XNRE 1UDQA 4DV1I 3D4JA 2E5LE 1PIEA 1XMOE 3U1KA 4LF5E 3T1YI 1ZXMA 4LF7E 2UXCE 1RR9A 4LFCE 1RREA 1XMQI 1Z0TA 4DV4E 2UXBI 2V2QA 3GMEA 2O3ZA 4DUZI 1UDNA 4P52A 4OKGA 4B3ME 4DV5I 1ELOA 3GONA 4DV1E 1N0VC 2EFGA 2NN6C 4DU8A 3Q1QA 2GO3A 3T1YE 4OO1D 2PNZA 3P3EA 1XMQE 4LF9I 2NN6E 5LMUI 2UXBE 2UUAI 3ZKBA 4IZJD 1N32E 4KHPI 4JI2I 4DUZE 2NN6B 4DPTA 4X65I 4IFDD 1ZM2A 4DV5E 3DD6A 5FWKA 5DNLA 3PRYA 5ELWA 2BR2A 4DR6I 1IBKI 4LF9E 4BA1A 5LMUE 5DNXA 2UUAE 1Y4UA 2E1RA 4OO1A 4KHPE 4JI2E 5IWAI 1E3HA 1Z0WA 2BA1G 5K36F 5C0XD 4JI4I 3J7AG 2Z5EA 4DV3E 3V2UC 2HK3A 4DPWA 2UUCI 4AM3A 4JYAI 2J65A 4FW9A 4IFDA 5JEAF 1HK7A 3KRNA 2PO1A 1FKAE 2HHHI 4DR6E 3HULA 2JEBA 1IBKE 5DRPA 5IWAE 2C38A 4DR5I 4DPXA 1H74A 1VI7A 2PO2B 2NPFA 1MX0A 3PYEA 4JI4E 2VESA 4IZKA 1Y60A 2UUCE 4JYAE 1S4EA 3M6AA 5C0XA 2HHHE 4NXNI 2WNRB 3WU3A 1HR0I 1KTVA 2F1DA 2GQ0A 4U3DA 4DR1I 1Z0CA 4DR5E 2DEIA 4LOMA 1J5EI 1NZ0A 4AQYI 2A2DA 3LPSA 3J7AM 1H72C 4HYMA 4WUCA 4NXNE 4DXLA 5K36C 1HR0E 1Z0EA 3ZZ0A 4DR1E 2HFSA 4Z7CA 3OTOI 5K36E 4DR7E 4U3BA 1D6TA 1J5EE 1H7SA 4AQYE 3PS3A 5JEAE 5K36B 3J81C 4JG4A 3WU6A 1KIJA 1UEKA 2CGEA 3B82A 4HXZA 2PO0B 4XTJA 4BA2A 4LFAI 3OTOE 2GO4A 2C39B 4FW5A 1MG7A 1Z0GA 4DR3I 3GCMA 4MU0A 2O1VA 1HNWI 1EA6A 2R42A 4OO1F 4JI3I 4MDTA 1QZRA 3J81Q 1FI4A 4LFAE 1N32I 2C37B 2AJ4A 2BM1A 3M85G 5FLXC 4JI0I 2JE6A 3P06A 3PYDA 3CDJA 4DR3E 4IFDF 2ZBKB 2Z5BA 4IS9A 3HJCA 5A2QC 1HNWE 1YHCA 4MQYA 3CDIA 2V34A 2JT2A 4JI3E 2HFUA 2IOPA 3WU4A 4LF8I 1R6MA 2IERA 3L7ZB 3JAMC 4JI0E 1KKHA 4HACA 1FJGI 3QT8A 4JI8I 3B78A 5C0XF 4RPFA 4DR4I 2X7IA 3M85D 2PNZB 4B3TI 1FWKA 4PU9A 2JEAB 2V2ZA 4UT4A 4AIMA 3WU5A 1IBMI 4LF8E 5EKWA 3ZZTA 4NXME 3CWVA 4OX9I 4IZJA 1FJGE 4OO1C 4JI8E 4MU4A 4DV0I 4DR4E 2BV3A 2BR2B 1MU5A 4OO1E 4B3TE 3JAMQ 4USMA 4GKKI 4BA1B 2VF3A 2V8PA 2F4VI 1VISA 4OO1B 2PNLA 4ZVIA 2UU9I 5LMNI 1IBME 4URLA 1KVKA 3M7ND 4IFDE 4HY1A 4OX9E 3PS1A 1ZM3A 1B63A 1HNZI 2O1WA 2PO2A 4DV0E 2PO1B 2CG9A 1PVGA 4GKKE 4ISAA 1DARA 2JEBB 4B3RI 2F4VE 2Q2EB 4JI7I 3PYFA 4DV7E 2C38B 2UU9E 5LMNE 1P42A 4JI5I 4DR7I 3LTOA 1Z5BA 3P3GA 2ZITA 5C0XE 2HKJA 3P76A 5K36D 1HNZE 2Z5CA 1WUUA 1PKPA 2HK2A 2IESA 1NHJA 1Z0BA 1UDSA 4MYTA 4B3RE 1OYPA 4FWGA 5DRRA 4GQUA 3V5RA 3J80C 4JI7E 4QNJA 1E3PA 4FWDA 1N0UA 1RHYA 1XXEA 5JEAC 4JI5E 3K17A 4KQVA 3Q6NA 1S16A 4DR2I 1N33I 5GMEA 5JEAB 4GKJI 2WW4A 4MU1A 4X66I 4I3HA 4PRVA 1R6LA 1OYRA 1N34I 4UTGA 3Q6MA 1BKNA 2WP8B 1B62A 1A6FA 2OI2A 4DR2E 1N33E 2V2VA 2IOQA 4GKJE 1Z5CA 4FW3A 4DPYA 4X66E 4JI1I 4BA2B 4DUYI 4LF4I 1N34E 2NN6D 1I94I 1U2RA 2C37A 2HKEA 3NZKA 3ZKDA 5DROA 4DU7A 2DEJA 4FW6A 3QT7A 2PNMA 4LFBI 3K1JA 1OJ4A 3H1CA 4K0KI 4LCHA 4JI1E 4DUYE 4LF4E 2O1TA 2UXDI 1FWLA 4J3DA 4NXMI 2BA0D 2JE6B 4DV3I 3P3CA 2NN6A 2Z5BB 3L7ZA 2ZM6I 4LFBE 4OZEA 1Y6ZA 5FLXQ 1XNQI 3M7NG 4K0KE 3ZZUA 5A2QQ 2UXDE 2JEAA 3H4LA 3ZM7A 4DV6I 4LCGA 4HACB
chains in the Genus database with same CATH topology
2J65A 3PS3A 4U3DA 2IERA 3UHMA 3PS2A 4J3DA 4MDTA 4FW3A 4LCFA 1P42A 2O3ZA 5DRQA 3P3CA 5DRPA 4FW4A 4FW7A 3P3GA 4OKGA 3P76A 1YH8A 4OZEA 2IESA 3NZKA 5DROA 4IS9A 4FW6A 2GO4A 2VESA 3PS1A 2GO3A 4FW5A 1YHCA 4MQYA 4U3BA 3U1YA 5DRRA 3P3EA 4ISAA 2JT2A 4LCHA 4LCGA 1XXEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J65 A;  3PS3 A;  4U3D A;  2IER A;  3UHM A;  3PS2 A;  4J3D A;  4MDT A;  4FW3 A;  4LCF A;  1P42 A;  2O3Z A;  5DRQ A;  3P3C A;  5DRP A;  4FW4 A;  4FW7 A;  3P3G A;  4OKG A;  3P76 A;  1YH8 A;  4OZE A;  2IES A;  3NZK A;  5DRO A;  4IS9 A;  4FW6 A;  2GO4 A;  2VES A;  3PS1 A;  2GO3 A;  4FW5 A;  1YHC A;  4MQY A;  4U3B A;  3U1Y A;  5DRR A;  3P3E A;  4ISA A;  2JT2 A;  4LCH A;  4LCG A;  1XXE A; 
#chains in the Genus database with same CATH topology
 1ZM4 A;  2J7K A;  3UHM A;  2ZM6 E;  2AE8 A;  4B3S I;  4AID A;  3GLL A;  4FW4 A;  3T1H I;  1XNQ E;  4P7A A;  1Y5Y A;  4IFD C;  4Z7Y A;  4DV7 I;  1YH8 A;  3F0N A;  4MU3 A;  1H73 A;  4DV6 E;  1I94 E;  4IZJ B;  4X65 E;  2XEX A;  4IFD B;  3HKM A;  5BR8 I;  2CZ9 A;  4B3S E;  4X62 I;  1ZXN A;  1H7U A;  1Z0V A;  1USV A;  3T1H E;  1K47 A;  4YHH I;  4X64 I;  2WNR A;  5C0X C;  4LCF A;  4DV2 I;  3K85 A;  5GMD A;  4FW7 A;  5IT9 C;  1FNM A;  4IZK B;  2A2C A;  1HNX I;  5BR8 E;  5LL6 R;  4PRX A;  5JEA D;  5C0X B;  4X62 E;  4JV5 I;  2BA1 D;  2R3V A;  4R1F A;  4YHH E;  4X64 E;  4MYU A;  1Z5A A;  4DV2 E;  4EMD A;  3PYG A;  4USK A;  4DPU A;  3PS2 A;  1IBL I;  2Z5C B;  1XHK A;  2VQE I;  2BM0 A;  4LF6 I;  4FWH A;  4YY3 I;  1HNX E;  1NHI A;  3QT6 A;  5DRQ A;  4JI6 I;  1N36 I;  5K36 A;  2VQF I;  1OYS A;  4JV5 E;  5IT9 Q;  3B4T A;  1Y4S A;  1Z59 A;  3B8H A;  4WUB A;  2PO0 A;  4NBQ A;  5JEA A;  4FN5 A;  3U1Y A;  2NN6 F;  3QT5 A;  1IBL E;  2VQE E;  4M1K A;  2UUB I;  2C39 A;  3J80 Q;  4YY3 E;  4LF6 E;  2LJP A;  2WP8 A;  1UDO A;  1XNR I;  4WUD A;  4JI6 E;  1N36 E;  2E5L I;  2VQF E;  1XMO I;  4ED4 A;  4LF5 I;  4N3O A;  4QNK A;  2UXC I;  2CVE A;  5EL9 A;  4LF7 I;  4LFC I;  5L3J A;  2BA0 G;  4LPF A;  1EI1 A;  2O1U A;  1ZM9 A;  4DV4 I;  2GS8 A;  3LNU A;  1USU A;  1NHH A;  2X36 A;  2UUB E;  4B3M I;  1XNR E;  1UDQ A;  4DV1 I;  3D4J A;  2E5L E;  1PIE A;  1XMO E;  3U1K A;  4LF5 E;  3T1Y I;  1ZXM A;  4LF7 E;  2UXC E;  1RR9 A;  4LFC E;  1RRE A;  1XMQ I;  1Z0T A;  4DV4 E;  2UXB I;  2V2Q A;  3GME A;  2O3Z A;  4DUZ I;  1UDN A;  4P52 A;  4OKG A;  4B3M E;  4DV5 I;  1ELO A;  3GON A;  4DV1 E;  1N0V C;  2EFG A;  2NN6 C;  4DU8 A;  3Q1Q A;  2GO3 A;  3T1Y E;  4OO1 D;  2PNZ A;  3P3E A;  1XMQ E;  4LF9 I;  2NN6 E;  5LMU I;  2UXB E;  2UUA I;  3ZKB A;  4IZJ D;  1N32 E;  4KHP I;  4JI2 I;  4DUZ E;  2NN6 B;  4DPT A;  4X65 I;  4IFD D;  1ZM2 A;  4DV5 E;  3DD6 A;  5FWK A;  5DNL A;  3PRY A;  5ELW A;  2BR2 A;  4DR6 I;  1IBK I;  4LF9 E;  4BA1 A;  5LMU E;  5DNX A;  2UUA E;  1Y4U A;  2E1R A;  4OO1 A;  4KHP E;  4JI2 E;  5IWA I;  1E3H A;  1Z0W A;  2BA1 G;  5K36 F;  5C0X D;  4JI4 I;  3J7A G;  2Z5E A;  4DV3 E;  3V2U C;  2HK3 A;  4DPW A;  2UUC I;  4AM3 A;  4JYA I;  2J65 A;  4FW9 A;  4IFD A;  5JEA F;  1HK7 A;  3KRN A;  2PO1 A;  1FKA E;  2HHH I;  4DR6 E;  3HUL A;  2JEB A;  1IBK E;  5DRP A;  5IWA E;  2C38 A;  4DR5 I;  4DPX A;  1H74 A;  1VI7 A;  2PO2 B;  2NPF A;  1MX0 A;  3PYE A;  4JI4 E;  2VES A;  4IZK A;  1Y60 A;  2UUC E;  4JYA E;  1S4E A;  3M6A A;  5C0X A;  2HHH E;  4NXN I;  2WNR B;  3WU3 A;  1HR0 I;  1KTV A;  2F1D A;  2GQ0 A;  4U3D A;  4DR1 I;  1Z0C A;  4DR5 E;  2DEI A;  4LOM A;  1J5E I;  1NZ0 A;  4AQY I;  2A2D A;  3LPS A;  3J7A M;  1H72 C;  4HYM A;  4WUC A;  4NXN E;  4DXL A;  5K36 C;  1HR0 E;  1Z0E A;  3ZZ0 A;  4DR1 E;  2HFS A;  4Z7C A;  3OTO I;  5K36 E;  4DR7 E;  4U3B A;  1D6T A;  1J5E E;  1H7S A;  4AQY E;  3PS3 A;  5JEA E;  5K36 B;  3J81 C;  4JG4 A;  3WU6 A;  1KIJ A;  1UEK A;  2CGE A;  3B82 A;  4HXZ A;  2PO0 B;  4XTJ A;  4BA2 A;  4LFA I;  3OTO E;  2GO4 A;  2C39 B;  4FW5 A;  1MG7 A;  1Z0G A;  4DR3 I;  3GCM A;  4MU0 A;  2O1V A;  1HNW I;  1EA6 A;  2R42 A;  4OO1 F;  4JI3 I;  4MDT A;  1QZR A;  3J81 Q;  1FI4 A;  4LFA E;  1N32 I;  2C37 B;  2AJ4 A;  2BM1 A;  3M85 G;  5FLX C;  4JI0 I;  2JE6 A;  3P06 A;  3PYD A;  3CDJ A;  4DR3 E;  4IFD F;  2ZBK B;  2Z5B A;  4IS9 A;  3HJC A;  5A2Q C;  1HNW E;  1YHC A;  4MQY A;  3CDI A;  2V34 A;  2JT2 A;  4JI3 E;  2HFU A;  2IOP A;  3WU4 A;  4LF8 I;  1R6M A;  2IER A;  3L7Z B;  3JAM C;  4JI0 E;  1KKH A;  4HAC A;  1FJG I;  3QT8 A;  4JI8 I;  3B78 A;  5C0X F;  4RPF A;  4DR4 I;  2X7I A;  3M85 D;  2PNZ B;  4B3T I;  1FWK A;  4PU9 A;  2JEA B;  2V2Z A;  4UT4 A;  4AIM A;  3WU5 A;  1IBM I;  4LF8 E;  5EKW A;  3ZZT A;  4NXM E;  3CWV A;  4OX9 I;  4IZJ A;  1FJG E;  4OO1 C;  4JI8 E;  4MU4 A;  4DV0 I;  4DR4 E;  2BV3 A;  2BR2 B;  1MU5 A;  4OO1 E;  4B3T E;  3JAM Q;  4USM A;  4GKK I;  4BA1 B;  2VF3 A;  2V8P A;  2F4V I;  1VIS A;  4OO1 B;  2PNL A;  4ZVI A;  2UU9 I;  5LMN I;  1IBM E;  4URL A;  1KVK A;  3M7N D;  4IFD E;  4HY1 A;  4OX9 E;  3PS1 A;  1ZM3 A;  1B63 A;  1HNZ I;  2O1W A;  2PO2 A;  4DV0 E;  2PO1 B;  2CG9 A;  1PVG A;  4GKK E;  4ISA A;  1DAR A;  2JEB B;  4B3R I;  2F4V E;  2Q2E B;  4JI7 I;  3PYF A;  4DV7 E;  2C38 B;  2UU9 E;  5LMN E;  1P42 A;  4JI5 I;  4DR7 I;  3LTO A;  1Z5B A;  3P3G A;  2ZIT A;  5C0X E;  2HKJ A;  3P76 A;  5K36 D;  1HNZ E;  2Z5C A;  1WUU A;  1PKP A;  2HK2 A;  2IES A;  1NHJ A;  1Z0B A;  1UDS A;  4MYT A;  4B3R E;  1OYP A;  4FWG A;  5DRR A;  4GQU A;  3V5R A;  3J80 C;  4JI7 E;  4QNJ A;  1E3P A;  4FWD A;  1N0U A;  1RHY A;  1XXE A;  5JEA C;  4JI5 E;  3K17 A;  4KQV A;  3Q6N A;  1S16 A;  4DR2 I;  1N33 I;  5GME A;  5JEA B;  4GKJ I;  2WW4 A;  4MU1 A;  4X66 I;  4I3H A;  4PRV A;  1R6L A;  1OYR A;  1N34 I;  4UTG A;  3Q6M A;  1BKN A;  2WP8 B;  1B62 A;  1A6F A;  2OI2 A;  4DR2 E;  1N33 E;  2V2V A;  2IOQ A;  4GKJ E;  1Z5C A;  4FW3 A;  4DPY A;  4X66 E;  4JI1 I;  4BA2 B;  4DUY I;  4LF4 I;  1N34 E;  2NN6 D;  1I94 I;  1U2R A;  2C37 A;  2HKE A;  3NZK A;  3ZKD A;  5DRO A;  4DU7 A;  2DEJ A;  4FW6 A;  3QT7 A;  2PNM A;  4LFB I;  3K1J A;  1OJ4 A;  3H1C A;  4K0K I;  4LCH A;  4JI1 E;  4DUY E;  4LF4 E;  2O1T A;  2UXD I;  1FWL A;  4J3D A;  4NXM I;  2BA0 D;  2JE6 B;  4DV3 I;  3P3C A;  2NN6 A;  2Z5B B;  3L7Z A;  2ZM6 I;  4LFB E;  4OZE A;  1Y6Z A;  5FLX Q;  1XNQ I;  3M7N G;  4K0K E;  3ZZU A;  5A2Q Q;  2UXD E;  2JEA A;  3H4L A;  3ZM7 A;  4DV6 I;  4LCG A;  4HAC B; 
#chains in the Genus database with same CATH homology
 2J65 A;  3PS3 A;  4U3D A;  2IER A;  3UHM A;  3PS2 A;  4J3D A;  4MDT A;  4FW3 A;  4LCF A;  1P42 A;  2O3Z A;  5DRQ A;  3P3C A;  5DRP A;  4FW4 A;  4FW7 A;  3P3G A;  4OKG A;  3P76 A;  1YH8 A;  4OZE A;  2IES A;  3NZK A;  5DRO A;  4IS9 A;  4FW6 A;  2GO4 A;  2VES A;  3PS1 A;  2GO3 A;  4FW5 A;  1YHC A;  4MQY A;  4U3B A;  3U1Y A;  5DRR A;  3P3E A;  4ISA A;  2JT2 A;  4LCH A;  4LCG A;  1XXE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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