2O3ZA

X-ray crystal structure of lpxc complexed with 3-heptyloxybenzoate
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
267
structure length
267
Chain Sequence
GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Amphipathic benzoic acid derivatives: synthesis and binding in the hydrophobic tunnel of the zinc deacetylase LpxC.
pubmed doi rcsb
molecule tags Hydrolase
source organism Aquifex aeolicus
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 91
structure length 267
sequence length 267
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2006-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 2o3zA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 2o3zA02
4OKGA 2VESA 1YH8A 3PS1A 3PS2A 1XXEA 4ISAA 3P3EA 4U3BA 1P42A 4FW5A 2IERA 5DRQA 3P3CA 4J3DA 4FW3A 3U1YA 4MQYA 4FW4A 3P76A 3UHMA 1YHCA 2J65A 4LCFA 4LCGA 2GO3A 4LCHA 2JT2A 4IS9A 5DROA 2GO4A 5DRPA 4FW6A 4OZEA 3P3GA 3PS3A 3NZKA 4MDTA 5DRRA 4FW7A 2IESA 2O3ZA 4U3DA
chains in the Genus database with same CATH superfamily
4X64I 2CVEA 4AIDA 1NHIA 1N36E 2PNZA 2BR2B 4HACA 4ISAA 2ZBKB 3OTOI 1P42A 4FW5A 3B4TA 2X7IA 2OI2A 3PYEA 3F0NA 2C39B 4OO1B 2UUAE 1IBME 4NXNI 3DD6A 1Z5BA 5C0XA 2UU9E 4DUYE 3P06A 4KHPI 4DU8A 3T1HE 4DPUA 4DV5E 1N33E 2CGEA 4LOMA 2JE6A 5JEAA 2E1RA 4MYUA 2DEJA 3L7ZB 1UEKA 4UTGA 4DPWA 4JI3E 1H73A 3ZM7A 4X62E 4DR6I 1J5EE 2F4VI 5IWAE 4MU4A 4DV0I 4IZJB 1N36I 4JI2I 2GQ0A 4OO1D 3J80Q 4LCFA 2HK2A 4JI0I 5DROA 2WP8B 2VQEE 4YHHE 4LFCE 3WU3A 2IESA 2O3ZA 2X36A 1PKPA 1N33I 4MU3A 3P3EA 1USUA 1FI4A 2Z5EA 2GS8A 3M7NG 4FWDA 4NXME 4OX9I 4J3DA 2V2ZA 2BA1D 1XMQI 4DUZI 4IZJD 1IBLE 4EMDA 4HY1A 4LFBE 4OZEA 2WNRB 2JEAA 4DV4E 4USKA 4LFAE 4FW6A 1HR0E 2C38B 1XXEA 2F1DA 4JI4E 4LF9I 4U3BA 1H72C 3CWVA 3V5RA 5LMNI 1OYRA 1VI7A 1VISA 4LF4E 1Z0GA 4LF8E 5IT9C 3T1YI 1Z0BA 2GO3A 4X64E 2PO0B 4DV7E 4FN5A 4DPTA 3PS3A 4NBQA 3Q6MA 3OTOE 3CDIA 2R3VA 2AJ4A 2Z5CB 2V2VA 1N32I 4MU1A 4NXNE 2NN6C 1KIJA 4GKKI 2NN6E 3GCMA 5DRQA 4DV2E 4B3TI 4KHPE 4JI1E 4WUDA 3ZZ0A 4AQYI 1XMOI 2HHHI 5LL6R 2VF3A 2JT2A 2J7KA 4OO1F 2UXBE 1DARA 1N34E 4DR6E 5ELWA 3J7AG 2IOPA 4DV0E 1ZXMA 4LPFA 1NZ0A 2VESA 4DV7I 4JI2E 2UUCI 3QT8A 2JEBA 5K36C 4JI0E 1Z0VA 4URLA 4IFDC 5K36E 4YY3E 1ELOA 5IT9Q 4IFDE 4JI8E 3M85D 1YHCA 4B3RE 1S4EA 4DV2I 3M6AA 4JI1I 4P52A 4X66I 2XEXA 3LNUA 2PO2B 2NN6B 1D6TA 3UHMA 1Y4UA 4X65I 4OX9E 3PYGA 1XMQE 4DUZE 4LF5I 2UXBI 1N34I 1H7UA 2C37B 2UUBE 1Y60A 4UT4A 4GQUA 1MG7A 2BM0A 4FW4A 2UXDI 4BA2B 4B3MI 4DV1I 4JYAI 2Z5BB 4YY3I 1FKAE 4BA1B 4LF9E 1QZRA 4JI8I 1EA6A 1XNQI 1HNXE 1Z59A 4B3RI 2A2DA 3HKMA 5LMNE 3B8HA 2NN6D 5K36B 3KRNA 3QT6A 4IFDB 1S16A 2LJPA 1U2RA 3Q1QA 3QT7A 2BR2A 3T1YE 1EI1A 1BKNA 4DR7E 3JAMC 2C39A 4OO1A 4MYTA 2BM1A 3D4JA 5C0XC 2UUBI 3V2UC 5FWKA 5LMUI 1FNMA 1FJGE 2R42A 4JI5I 1HNZE 1N32E 5DRRA 2PO1B 1Z5CA 5JEAC 4GKKE 1N0UA 5GMDA 4B3SE 4B3TE 1PIEA 4DPYA 2HFSA 3L7ZA 3M7ND 1Z0EA 4AQYE 1XMOE 5K36D 1HNXI 2HHHE 4IFDD 4XTJA 1R6LA 4DR1I 1UDSA 5DNXA 2AE8A 3GMEA 4IZJA 1IBKI 3CDJA 4DR7I 4IZKB 1XNRI 4M1KA 2PNZB 2WW4A 2UUCE 2WP8A 4HACB 3GLLA 1Y5YA 1FJGI 4DU7A 1FWKA 4DPXA 4HXZA 2A2CA 2BA0G 1HNZI 1Z0CA 4ED4A 4LF6I 2IERA 3P3CA 4B3SI 3JAMQ 2ZM6I 5C0XB 4MU0A 1HK7A 4PU9A 1Z0WA 4JI6I 1N0VC 4MQYA 4X66E 3LPSA 4AM3A 3PYDA 2JE6B 5JEAB 2HKEA 4X65E 3Q6NA 2O1TA 4DR4I 4LF5E 4GKJI 4MDTA 1ZXNA 4HYMA 2NPFA 2WNRA 3PS1A 1YH8A 3PS2A 5L3JA 3H1CA 1WUUA 2UXDE 2O1UA 2C38A 4B3ME 4DV1E 3J81C 2NN6F 4JYAE 1Z0TA 3U1YA 1RR9A 4DR5I 5C0XD 2J65A 1XNQE 1K47A 3ZZTA 4KQVA 4DR3E 4DV6I 3HJCA 5EL9A 5JEAD 4LF7I 1KVKA 2PO0A 4PRXA 1B62A 2IOQA 4AIMA 5A2QC 4K0KI 3WU5A 2VQFI 2Z5CA 3ZZUA 1KTVA 5GMEA 5DNLA 5LMUE 4JG4A 1USVA 5BR8I 2CG9A 4JI5E 3H4LA 1I94I 2PNLA 5K36F 3K85A 4IFDF 1RREA 2JEAB 4LCHA 2HK3A 1H7SA 1MX0A 1MU5A 1E3PA 4P7AA 1PVGA 4DR2I 2HFUA 4FW7A 2E5LE 2Q2EB 3QT5A 4WUBA 1KKHA 4DR3I 4JV5I 3K1JA 4DR1E 1UDOA 3HULA 4FW9A 3J81Q 5EKWA 4R1FA 3J7AM 1IBKE 2BA1G 3GONA 4I3HA 3PYFA 4JI7E 5FLXC 1XNRE 2DEIA 2UUAI 4IS9A 1IBMI 2GO4A 4PRVA 5DRPA 4ZVIA 4Z7YA 5C0XE 3P3GA 2BV3A 3NZKA 1XHKA 4LF6E 2UU9I 5A2QQ 2UXCE 4DUYI 1Z5AA 4U3DA 3T1HI 4DV5I 2PO2A 5JEAE 2ZM6E 2O1VA 2NN6A 4JI6E 1FWLA 1UDNA 4QNKA 3ZKBA 4DXLA 1HNWE 1B63A 2E5LI 2PNMA 4WUCA 4JI3I 3B82A 4DV3E 4X62I 1J5EI 4DR4E 2C37A 4RPFA 4GKJE 3P76A 1R6MA 5IWAI 4BA2A 5C0XF 4JI7I 3WU6A 2V8PA 2Z5BA 4QNJA 4BA1A 2VQEI 4YHHI 1ZM3A 5JEAF 2JEBB 4LFCI 2HKJA 1Y4SA 4DR5E 1UDQA 5FLXQ 2UXCI 5K36A 4FWHA 2O1WA 2EFGA 4IFDA 4DV6E 3ZKDA 1RHYA 1ZM2A 2V34A 4LF7E 1HNWI 4NXMI 4OO1C 4LCGA 1E3HA 3WU4A 4OO1E 4FWGA 4DV3I 3LTOA 4K0KE 1Y6ZA 1NHHA 1IBLI 2VQFE 1A6FA 1OYSA 1OJ4A 4N3OA 4LFBI 2BA0D 4OKGA 2PO1A 5BR8E 1I94E 4DV4I 4LFAI 2ZITA 3U1KA 3B78A 1HR0I 4FW3A 1NHJA 4JI4I 2CZ9A 3PRYA 4DR2E 3M85G 1ZM4A 3K17A 1ZM9A 1H74A 2V2QA 4JV5E 3J80C 4USMA 4Z7CA 2F4VE 4LF4I 4LF8I 1OYPA 4IZKA
chains in the Genus database with same CATH topology
4OKGA 2VESA 1YH8A 3PS1A 3PS2A 1XXEA 4ISAA 3P3EA 4U3BA 1P42A 4FW5A 2IERA 5DRQA 3P3CA 4J3DA 4FW3A 3U1YA 4MQYA 4FW4A 3P76A 3UHMA 1YHCA 2J65A 4LCFA 4LCGA 2GO3A 4LCHA 2JT2A 4IS9A 5DROA 2GO4A 5DRPA 4FW6A 4OZEA 3P3GA 3PS3A 3NZKA 4MDTA 5DRRA 4FW7A 2IESA 2O3ZA 4U3DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OKG A;  2VES A;  1YH8 A;  3PS1 A;  3PS2 A;  1XXE A;  4ISA A;  3P3E A;  4U3B A;  1P42 A;  4FW5 A;  2IER A;  5DRQ A;  3P3C A;  4J3D A;  4FW3 A;  3U1Y A;  4MQY A;  4FW4 A;  3P76 A;  3UHM A;  1YHC A;  2J65 A;  4LCF A;  4LCG A;  2GO3 A;  4LCH A;  2JT2 A;  4IS9 A;  5DRO A;  2GO4 A;  5DRP A;  4FW6 A;  4OZE A;  3P3G A;  3PS3 A;  3NZK A;  4MDT A;  5DRR A;  4FW7 A;  2IES A;  2O3Z A;  4U3D A; 
#chains in the Genus database with same CATH topology
 4X64 I;  2CVE A;  4AID A;  1NHI A;  1N36 E;  2PNZ A;  2BR2 B;  4HAC A;  4ISA A;  2ZBK B;  3OTO I;  1P42 A;  4FW5 A;  3B4T A;  2X7I A;  2OI2 A;  3PYE A;  3F0N A;  2C39 B;  4OO1 B;  2UUA E;  1IBM E;  4NXN I;  3DD6 A;  1Z5B A;  5C0X A;  2UU9 E;  4DUY E;  3P06 A;  4KHP I;  4DU8 A;  3T1H E;  4DPU A;  4DV5 E;  1N33 E;  2CGE A;  4LOM A;  2JE6 A;  5JEA A;  2E1R A;  4MYU A;  2DEJ A;  3L7Z B;  1UEK A;  4UTG A;  4DPW A;  4JI3 E;  1H73 A;  3ZM7 A;  4X62 E;  4DR6 I;  1J5E E;  2F4V I;  5IWA E;  4MU4 A;  4DV0 I;  4IZJ B;  1N36 I;  4JI2 I;  2GQ0 A;  4OO1 D;  3J80 Q;  4LCF A;  2HK2 A;  4JI0 I;  5DRO A;  2WP8 B;  2VQE E;  4YHH E;  4LFC E;  3WU3 A;  2IES A;  2O3Z A;  2X36 A;  1PKP A;  1N33 I;  4MU3 A;  3P3E A;  1USU A;  1FI4 A;  2Z5E A;  2GS8 A;  3M7N G;  4FWD A;  4NXM E;  4OX9 I;  4J3D A;  2V2Z A;  2BA1 D;  1XMQ I;  4DUZ I;  4IZJ D;  1IBL E;  4EMD A;  4HY1 A;  4LFB E;  4OZE A;  2WNR B;  2JEA A;  4DV4 E;  4USK A;  4LFA E;  4FW6 A;  1HR0 E;  2C38 B;  1XXE A;  2F1D A;  4JI4 E;  4LF9 I;  4U3B A;  1H72 C;  3CWV A;  3V5R A;  5LMN I;  1OYR A;  1VI7 A;  1VIS A;  4LF4 E;  1Z0G A;  4LF8 E;  5IT9 C;  3T1Y I;  1Z0B A;  2GO3 A;  4X64 E;  2PO0 B;  4DV7 E;  4FN5 A;  4DPT A;  3PS3 A;  4NBQ A;  3Q6M A;  3OTO E;  3CDI A;  2R3V A;  2AJ4 A;  2Z5C B;  2V2V A;  1N32 I;  4MU1 A;  4NXN E;  2NN6 C;  1KIJ A;  4GKK I;  2NN6 E;  3GCM A;  5DRQ A;  4DV2 E;  4B3T I;  4KHP E;  4JI1 E;  4WUD A;  3ZZ0 A;  4AQY I;  1XMO I;  2HHH I;  5LL6 R;  2VF3 A;  2JT2 A;  2J7K A;  4OO1 F;  2UXB E;  1DAR A;  1N34 E;  4DR6 E;  5ELW A;  3J7A G;  2IOP A;  4DV0 E;  1ZXM A;  4LPF A;  1NZ0 A;  2VES A;  4DV7 I;  4JI2 E;  2UUC I;  3QT8 A;  2JEB A;  5K36 C;  4JI0 E;  1Z0V A;  4URL A;  4IFD C;  5K36 E;  4YY3 E;  1ELO A;  5IT9 Q;  4IFD E;  4JI8 E;  3M85 D;  1YHC A;  4B3R E;  1S4E A;  4DV2 I;  3M6A A;  4JI1 I;  4P52 A;  4X66 I;  2XEX A;  3LNU A;  2PO2 B;  2NN6 B;  1D6T A;  3UHM A;  1Y4U A;  4X65 I;  4OX9 E;  3PYG A;  1XMQ E;  4DUZ E;  4LF5 I;  2UXB I;  1N34 I;  1H7U A;  2C37 B;  2UUB E;  1Y60 A;  4UT4 A;  4GQU A;  1MG7 A;  2BM0 A;  4FW4 A;  2UXD I;  4BA2 B;  4B3M I;  4DV1 I;  4JYA I;  2Z5B B;  4YY3 I;  1FKA E;  4BA1 B;  4LF9 E;  1QZR A;  4JI8 I;  1EA6 A;  1XNQ I;  1HNX E;  1Z59 A;  4B3R I;  2A2D A;  3HKM A;  5LMN E;  3B8H A;  2NN6 D;  5K36 B;  3KRN A;  3QT6 A;  4IFD B;  1S16 A;  2LJP A;  1U2R A;  3Q1Q A;  3QT7 A;  2BR2 A;  3T1Y E;  1EI1 A;  1BKN A;  4DR7 E;  3JAM C;  2C39 A;  4OO1 A;  4MYT A;  2BM1 A;  3D4J A;  5C0X C;  2UUB I;  3V2U C;  5FWK A;  5LMU I;  1FNM A;  1FJG E;  2R42 A;  4JI5 I;  1HNZ E;  1N32 E;  5DRR A;  2PO1 B;  1Z5C A;  5JEA C;  4GKK E;  1N0U A;  5GMD A;  4B3S E;  4B3T E;  1PIE A;  4DPY A;  2HFS A;  3L7Z A;  3M7N D;  1Z0E A;  4AQY E;  1XMO E;  5K36 D;  1HNX I;  2HHH E;  4IFD D;  4XTJ A;  1R6L A;  4DR1 I;  1UDS A;  5DNX A;  2AE8 A;  3GME A;  4IZJ A;  1IBK I;  3CDJ A;  4DR7 I;  4IZK B;  1XNR I;  4M1K A;  2PNZ B;  2WW4 A;  2UUC E;  2WP8 A;  4HAC B;  3GLL A;  1Y5Y A;  1FJG I;  4DU7 A;  1FWK A;  4DPX A;  4HXZ A;  2A2C A;  2BA0 G;  1HNZ I;  1Z0C A;  4ED4 A;  4LF6 I;  2IER A;  3P3C A;  4B3S I;  3JAM Q;  2ZM6 I;  5C0X B;  4MU0 A;  1HK7 A;  4PU9 A;  1Z0W A;  4JI6 I;  1N0V C;  4MQY A;  4X66 E;  3LPS A;  4AM3 A;  3PYD A;  2JE6 B;  5JEA B;  2HKE A;  4X65 E;  3Q6N A;  2O1T A;  4DR4 I;  4LF5 E;  4GKJ I;  4MDT A;  1ZXN A;  4HYM A;  2NPF A;  2WNR A;  3PS1 A;  1YH8 A;  3PS2 A;  5L3J A;  3H1C A;  1WUU A;  2UXD E;  2O1U A;  2C38 A;  4B3M E;  4DV1 E;  3J81 C;  2NN6 F;  4JYA E;  1Z0T A;  3U1Y A;  1RR9 A;  4DR5 I;  5C0X D;  2J65 A;  1XNQ E;  1K47 A;  3ZZT A;  4KQV A;  4DR3 E;  4DV6 I;  3HJC A;  5EL9 A;  5JEA D;  4LF7 I;  1KVK A;  2PO0 A;  4PRX A;  1B62 A;  2IOQ A;  4AIM A;  5A2Q C;  4K0K I;  3WU5 A;  2VQF I;  2Z5C A;  3ZZU A;  1KTV A;  5GME A;  5DNL A;  5LMU E;  4JG4 A;  1USV A;  5BR8 I;  2CG9 A;  4JI5 E;  3H4L A;  1I94 I;  2PNL A;  5K36 F;  3K85 A;  4IFD F;  1RRE A;  2JEA B;  4LCH A;  2HK3 A;  1H7S A;  1MX0 A;  1MU5 A;  1E3P A;  4P7A A;  1PVG A;  4DR2 I;  2HFU A;  4FW7 A;  2E5L E;  2Q2E B;  3QT5 A;  4WUB A;  1KKH A;  4DR3 I;  4JV5 I;  3K1J A;  4DR1 E;  1UDO A;  3HUL A;  4FW9 A;  3J81 Q;  5EKW A;  4R1F A;  3J7A M;  1IBK E;  2BA1 G;  3GON A;  4I3H A;  3PYF A;  4JI7 E;  5FLX C;  1XNR E;  2DEI A;  2UUA I;  4IS9 A;  1IBM I;  2GO4 A;  4PRV A;  5DRP A;  4ZVI A;  4Z7Y A;  5C0X E;  3P3G A;  2BV3 A;  3NZK A;  1XHK A;  4LF6 E;  2UU9 I;  5A2Q Q;  2UXC E;  4DUY I;  1Z5A A;  4U3D A;  3T1H I;  4DV5 I;  2PO2 A;  5JEA E;  2ZM6 E;  2O1V A;  2NN6 A;  4JI6 E;  1FWL A;  1UDN A;  4QNK A;  3ZKB A;  4DXL A;  1HNW E;  1B63 A;  2E5L I;  2PNM A;  4WUC A;  4JI3 I;  3B82 A;  4DV3 E;  4X62 I;  1J5E I;  4DR4 E;  2C37 A;  4RPF A;  4GKJ E;  3P76 A;  1R6M A;  5IWA I;  4BA2 A;  5C0X F;  4JI7 I;  3WU6 A;  2V8P A;  2Z5B A;  4QNJ A;  4BA1 A;  2VQE I;  4YHH I;  1ZM3 A;  5JEA F;  2JEB B;  4LFC I;  2HKJ A;  1Y4S A;  4DR5 E;  1UDQ A;  5FLX Q;  2UXC I;  5K36 A;  4FWH A;  2O1W A;  2EFG A;  4IFD A;  4DV6 E;  3ZKD A;  1RHY A;  1ZM2 A;  2V34 A;  4LF7 E;  1HNW I;  4NXM I;  4OO1 C;  4LCG A;  1E3H A;  3WU4 A;  4OO1 E;  4FWG A;  4DV3 I;  3LTO A;  4K0K E;  1Y6Z A;  1NHH A;  1IBL I;  2VQF E;  1A6F A;  1OYS A;  1OJ4 A;  4N3O A;  4LFB I;  2BA0 D;  4OKG A;  2PO1 A;  5BR8 E;  1I94 E;  4DV4 I;  4LFA I;  2ZIT A;  3U1K A;  3B78 A;  1HR0 I;  4FW3 A;  1NHJ A;  4JI4 I;  2CZ9 A;  3PRY A;  4DR2 E;  3M85 G;  1ZM4 A;  3K17 A;  1ZM9 A;  1H74 A;  2V2Q A;  4JV5 E;  3J80 C;  4USM A;  4Z7C A;  2F4V E;  4LF4 I;  4LF8 I;  1OYP A;  4IZK A; 
#chains in the Genus database with same CATH homology
 4OKG A;  2VES A;  1YH8 A;  3PS1 A;  3PS2 A;  1XXE A;  4ISA A;  3P3E A;  4U3B A;  1P42 A;  4FW5 A;  2IER A;  5DRQ A;  3P3C A;  4J3D A;  4FW3 A;  3U1Y A;  4MQY A;  4FW4 A;  3P76 A;  3UHM A;  1YHC A;  2J65 A;  4LCF A;  4LCG A;  2GO3 A;  4LCH A;  2JT2 A;  4IS9 A;  5DRO A;  2GO4 A;  5DRP A;  4FW6 A;  4OZE A;  3P3G A;  3PS3 A;  3NZK A;  4MDT A;  5DRR A;  4FW7 A;  2IES A;  2O3Z A;  4U3D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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