3NZK | Genus

Total Genus 94

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	94
sequence length	298
structure length	298
Chain Sequence	MIKQRTLKRIVQATGVGLHTGKKVTLTMRPAPANTGVIYRRTDLNPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIIIEVNAPEVPIMDGSASPFVYLLLDAGIEELNSAKKFLRLKETVRVEDGDKWAELSPFNGFRLDFTIDFNHPAIDSSTQRYRLDFSADSFVRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVVDDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVLAKQEAWEFVTFQDEAEMPLAFK

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Yersinia enterocolitica
publication title	Structure of the Metal-Dependent Deacetylase LpxC from Yersinia enterocolitica Complexed with the Potent Inhibitor CHIR-090 . pubmed doi rcsb
molecule keywords	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus	94
structure length	298
sequence length	298
chains with identical sequence	B
ec nomenclature	ec 3.5.1.33: N-acetylglucosamine deacetylase.
pdb deposition date	2010-07-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03331	LpxC	UDP-3-O-acyl N-acetylglycosamine deacetylase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.230.20	Alpha Beta	2-Layer Sandwich	Ribosomal Protein S5; domain 2	lpxc deacetylase, domain 1	3nzkA01
3.30.1700.10	Alpha Beta	2-Layer Sandwich	lpxc deacetylase, domain 1	lpxc deacetylase, domain 2	3nzkA02

4LCGA 4FW7A 4U3DA 5DRPA 5DRQA 4LCHA 4LCFA 3U1YA 3P3EA 1XXEA 3P3GA 2IESA 4FW4A 3PS1A 3P3CA 2GO3A 1YH8A 2GO4A 5DROA 2VESA 3UHMA 3PS3A 4MQYA 3NZKA 2JT2A 4OZEA 3PS2A 1YHCA 4FW5A 4J3DA 3P76A 4FW3A 4IS9A 2IERA 4MDTA 4FW6A 4ISAA 4U3BA 5DRRA 4OKGA 2J65A 1P42A 2O3ZA
chains in the Genus database with same CATH superfamily

3T1YI 1PKPA 4FW7A 1OYSA 4DV1E 4OO1B 2IESA 4LFCE 4IFDE 3GCMA 2GO3A 4DV1I 5GMDA 4GKJE 4LFCI 1XNRE 4JI5E 2WW4A 4MQYA 2NPFA 4GKJI 1MU5A 1XNRI 3ZKDA 4JI5I 1YHCA 2PNZA 5K36C 2JEBB 2NN6D 3PYGA 1QZRA 3M7ND 2IERA 1K47A 4DPTA 2PO1A 2IOPA 3WU6A 3M85D 4MU4A 4USKA 2V8PA 1NHJA 5BR8E 2IOQA 4N3OA 4X65E 5C0XE 1NHIA 4X65I 2WNRB 4MYUA 3OTOE 1MX0A 3HKMA 3T1HE 3K1JA 4IZJA 1S4EA 2JEAA 3OTOI 3T1HI 2Q2EB 1P42A 4B3RI 4DV2E 1Z0EA 1USUA 2XEXA 4OO1C 5DRQA 1ZM3A 5DNXA 4DV2I 1HR0E 1N0UA 4LF7E 1HR0I 4YY3E 1FJGE 4LF7I 1Z0WA 3ZZUA 2BM1A 2JEBA 4YY3I 4RPFA 1FJGI 4AIDA 1KTVA 1N0VC 4HACB 1H73A 5DNLA 3J81Q 4FW6A 4IZJD 2A2CA 1UEKA 4FW9A 2R42A 1HNWE 5JEAB 3M85G 1ZM9A 4LF6E 4JI7I 4R1FA 5IT9C 4IFDB 4DPUA 4LPFA 1B62A 1HNWI 1Z0VA 2DEIA 4LF6I 5FLXQ 4URLA 1HNXE 5DROA 3LPSA 4JYAE 1NHHA 1HNXI 4M1KA 3U1KA 3K17A 4MU3A 1H74A 4JYAI 5K36B 2R3VA 1U2RA 3J80Q 5JEAF 4DU7A 5FWKA 2V2VA 2V34A 3PYFA 3HJCA 4DR4I 1FWLA 1KKHA 4DV6E 4P7AA 2LJPA 4I3HA 4ED4A 5IWAE 4DV6I 1HNZI 5IWAI 4JV5E 4DV5E 5ELWA 4DV4E 2JT2A 4HACA 4JV5I 4DV5I 4DV3E 1N32E 4Z7CA 3LTOA 4DV4I 5K36F 2BA1G 4IS9A 2CVEA 1XMQE 1N33E 3P06A 3Q1QA 1Y4UA 2AE8A 4OKGA 5JEAA 1XMQI 4IZKB 1N33I 4IFDC 4JI8E 4JI6E 1IBLE 3QT6A 1UDOA 3ZM7A 1RREA 2VQFE 1KVKA 4JI8I 1IBLI 4JI6I 3DD6A 5LL6R 2CG9A 1USVA 1Y6ZA 2GO4A 3PS3A 2VQFI 3WU3A 4DR1E 5K36A 2V2ZA 3L7ZB 3HULA 2NN6E 4DR1I 4U3BA 4DR6E 3WU4A 1PIEA 4PRVA 1Z0BA 4ZVIA 4DR6I 5JEAD 1H72C 4B3TE 3J7AM 1UDSA 4OO1F 2UXCI 5L3JA 4B3TI 3KRNA 4YHHE 5C0XC 1KIJA 4UT4A 2ZITA 4YHHI 4OZEA 4OX9E 1XHKA 5K36D 4OX9I 4IZKA 4B3RE 3QT5A 5LMUE 1RR9A 5LMUI 2UUCE 4OO1A 3J81C 4HY1A 3WU5A 4LFAI 2UXBE 2HK2A 2UUCI 4BA2B 3CWVA 4GQUA 3CDIA 1YH8A 2UXBI 2Z5CB 1ZM4A 3L7ZA 1OYRA 2PO2B 4AM3A 5FLXC 4LF4I 4FW5A 1NZ0A 3ZKBA 4ISAA 4DR2E 4BA1B 4WUBA 3M7NG 2BR2B 4DR2I 4LF5E 4X64I 4JI7E 1MG7A 3J80C 4OO1D 4LF5I 3P3GA 2BA0D 2E1RA 2WP8B 2WNRA 2F1DA 1UDNA 2C38B 4DR5E 1H7UA 3ZZTA 4NBQA 4DR5I 2HFUA 4NXME 1Y60A 2CGEA 4LF8E 4DR4E 4BA2A 4KHPE 4NXMI 2VF3A 4LF8I 4QNJA 5EKWA 4IFDF 2O1TA 2Z5CA 4KHPI 1A6FA 1H7SA 2PO2A 2HFSA 1ZXNA 5C0XB 2C39B 2UU9E 1FNMA 4BA1A 4FW3A 3QT7A 1Y4SA 1WUUA 5LMNE 1RHYA 2ZBKB 2BR2A 4DPYA 1XMOE 2UU9I 3ZZ0A 5GMEA 5LMNI 1I94E 1XMOI 1XNQE 2O3ZA 4LF9E 1I94I 4IFDA 1E3HA 1XNQI 2WP8A 4B3SE 4LF9I 3B78A 3M6AA 3P3CA 3H4LA 4DUYE 4B3SI 2BA0G 3LNUA 5C0XF 2C38A 3V2UC 3NZKA 4DXLA 1ZXMA 4DUYI 4AQYE 4XTJA 4DV0E 2X36A 4MU0A 2NN6C 2ZM6E 1IBKE 4AQYI 4DV0I 3F0NA 3H1CA 2ZM6I 1J5EE 3J7AG 1IBKI 2JE6B 1B63A 1HK7A 3PYDA 1J5EI 2BM0A 1D6TA 3PRYA 5JEAE 2UXCE 4U3DA 4FWDA 4JI2E 4DU8A 2V2QA 4IFDD 4GKKE 4MU1A 2X7IA 4DUZE 4WUDA 4JI2I 3GONA 2UUAE 5C0XA 4Z7YA 4GKKI 2C39A 4DUZI 5A2QQ 3Q6NA 2UUAI 4EMDA 4JI4E 2E5LE 3JAMQ 4JI4I 5K36E 2E5LI 1EA6A 2Z5BB 4WUCA 2J65A 4JG4A 4DPWA 4FWGA 4LFAE 1Z0CA 2Z5EA 2O1VA 3P3EA 2UUBE 1ELOA 1R6MA 4B3ME 2PNLA 4UTGA 2A2DA 2UUBI 1VI7A 2VESA 2EFGA 1Z59A 1ZM2A 4LFBE 5C0XD 4B3MI 4JI1E 5BR8I 3B82A 4LF4E 3B8HA 2JE6A 4LFBI 4JI1I 4PRXA 2DEJA 2O1WA 1Z0GA 4JI3E 4P52A 1EI1A 1UDQA 1BKNA 4X64E 2HHHE 4JI3I 4DR7E 3PYEA 3GLLA 1FKAE 2HHHI 2HK3A 4LCFA 4DR7I 1R6LA 1FI4A 2O1UA 4X66E 4OO1E 4FW4A 3PS1A 4DV7E 2PO0B 4PU9A 4X66I 1E3PA 2C37B 4DV7I 2BA1D 4AIMA 2HKJA 2Z5BA 4JI0E 3P76A 2BV3A 1OJ4A 1Y5YA 1S16A 2NN6B 4JI0I 4HYMA 3GMEA 1FWKA 2J7KA 2VQEE 2F4VE 5DRPA 3B4TA 2VQEI 3V5RA 3CDJA 3U1YA 2F4VI 1XXEA 3K85A 4K0KE 4HXZA 1DARA 4DPXA 4K0KI 1OYPA 1N34E 3PS2A 3QT8A 2NN6F 1N34I 1Z5AA 2PNMA 2AJ4A 4MDTA 2PNZB 1Z5BA 1IBME 4NXNE 2UXDE 3D4JA 1PVGA 2CZ9A 5IT9Q 4NXNI 1IBMI 2UXDI 1N36E 2PO1B 4LCGA 2PO0A 4LCHA 1VISA 1N36I 4QNKA 2C37A 2GS8A 4FWHA 3Q6MA 2GQ0A 5EL9A 3UHMA 1Z0TA 4FN5A 2HKEA 2NN6A 4LOMA 4DR3E 4X62E 4MYTA 4J3DA 5A2QC 4DV3I 1N32I 1Z5CA 2OI2A 4X62I 4DR3I 1HNZE 3JAMC 5DRRA 3T1YE 4KQVA 5JEAC 4USMA 2JEAB 4IZJB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4LCG A;  4FW7 A;  4U3D A;  5DRP A;  5DRQ A;  4LCH A;  4LCF A;  3U1Y A;  3P3E A;  1XXE A;  3P3G A;  2IES A;  4FW4 A;  3PS1 A;  3P3C A;  2GO3 A;  1YH8 A;  2GO4 A;  5DRO A;  2VES A;  3UHM A;  3PS3 A;  4MQY A;  3NZK A;  2JT2 A;  4OZE A;  3PS2 A;  1YHC A;  4FW5 A;  4J3D A;  3P76 A;  4FW3 A;  4IS9 A;  2IER A;  4MDT A;  4FW6 A;  4ISA A;  4U3B A;  5DRR A;  4OKG A;  2J65 A;  1P42 A;  2O3Z A; 
#chains in the Genus database with same CATH topology
 3T1Y I;  1PKP A;  4FW7 A;  1OYS A;  4DV1 E;  4OO1 B;  2IES A;  4LFC E;  4IFD E;  3GCM A;  2GO3 A;  4DV1 I;  5GMD A;  4GKJ E;  4LFC I;  1XNR E;  4JI5 E;  2WW4 A;  4MQY A;  2NPF A;  4GKJ I;  1MU5 A;  1XNR I;  3ZKD A;  4JI5 I;  1YHC A;  2PNZ A;  5K36 C;  2JEB B;  2NN6 D;  3PYG A;  1QZR A;  3M7N D;  2IER A;  1K47 A;  4DPT A;  2PO1 A;  2IOP A;  3WU6 A;  3M85 D;  4MU4 A;  4USK A;  2V8P A;  1NHJ A;  5BR8 E;  2IOQ A;  4N3O A;  4X65 E;  5C0X E;  1NHI A;  4X65 I;  2WNR B;  4MYU A;  3OTO E;  1MX0 A;  3HKM A;  3T1H E;  3K1J A;  4IZJ A;  1S4E A;  2JEA A;  3OTO I;  3T1H I;  2Q2E B;  1P42 A;  4B3R I;  4DV2 E;  1Z0E A;  1USU A;  2XEX A;  4OO1 C;  5DRQ A;  1ZM3 A;  5DNX A;  4DV2 I;  1HR0 E;  1N0U A;  4LF7 E;  1HR0 I;  4YY3 E;  1FJG E;  4LF7 I;  1Z0W A;  3ZZU A;  2BM1 A;  2JEB A;  4YY3 I;  4RPF A;  1FJG I;  4AID A;  1KTV A;  1N0V C;  4HAC B;  1H73 A;  5DNL A;  3J81 Q;  4FW6 A;  4IZJ D;  2A2C A;  1UEK A;  4FW9 A;  2R42 A;  1HNW E;  5JEA B;  3M85 G;  1ZM9 A;  4LF6 E;  4JI7 I;  4R1F A;  5IT9 C;  4IFD B;  4DPU A;  4LPF A;  1B62 A;  1HNW I;  1Z0V A;  2DEI A;  4LF6 I;  5FLX Q;  4URL A;  1HNX E;  5DRO A;  3LPS A;  4JYA E;  1NHH A;  1HNX I;  4M1K A;  3U1K A;  3K17 A;  4MU3 A;  1H74 A;  4JYA I;  5K36 B;  2R3V A;  1U2R A;  3J80 Q;  5JEA F;  4DU7 A;  5FWK A;  2V2V A;  2V34 A;  3PYF A;  3HJC A;  4DR4 I;  1FWL A;  1KKH A;  4DV6 E;  4P7A A;  2LJP A;  4I3H A;  4ED4 A;  5IWA E;  4DV6 I;  1HNZ I;  5IWA I;  4JV5 E;  4DV5 E;  5ELW A;  4DV4 E;  2JT2 A;  4HAC A;  4JV5 I;  4DV5 I;  4DV3 E;  1N32 E;  4Z7C A;  3LTO A;  4DV4 I;  5K36 F;  2BA1 G;  4IS9 A;  2CVE A;  1XMQ E;  1N33 E;  3P06 A;  3Q1Q A;  1Y4U A;  2AE8 A;  4OKG A;  5JEA A;  1XMQ I;  4IZK B;  1N33 I;  4IFD C;  4JI8 E;  4JI6 E;  1IBL E;  3QT6 A;  1UDO A;  3ZM7 A;  1RRE A;  2VQF E;  1KVK A;  4JI8 I;  1IBL I;  4JI6 I;  3DD6 A;  5LL6 R;  2CG9 A;  1USV A;  1Y6Z A;  2GO4 A;  3PS3 A;  2VQF I;  3WU3 A;  4DR1 E;  5K36 A;  2V2Z A;  3L7Z B;  3HUL A;  2NN6 E;  4DR1 I;  4U3B A;  4DR6 E;  3WU4 A;  1PIE A;  4PRV A;  1Z0B A;  4ZVI A;  4DR6 I;  5JEA D;  1H72 C;  4B3T E;  3J7A M;  1UDS A;  4OO1 F;  2UXC I;  5L3J A;  4B3T I;  3KRN A;  4YHH E;  5C0X C;  1KIJ A;  4UT4 A;  2ZIT A;  4YHH I;  4OZE A;  4OX9 E;  1XHK A;  5K36 D;  4OX9 I;  4IZK A;  4B3R E;  3QT5 A;  5LMU E;  1RR9 A;  5LMU I;  2UUC E;  4OO1 A;  3J81 C;  4HY1 A;  3WU5 A;  4LFA I;  2UXB E;  2HK2 A;  2UUC I;  4BA2 B;  3CWV A;  4GQU A;  3CDI A;  1YH8 A;  2UXB I;  2Z5C B;  1ZM4 A;  3L7Z A;  1OYR A;  2PO2 B;  4AM3 A;  5FLX C;  4LF4 I;  4FW5 A;  1NZ0 A;  3ZKB A;  4ISA A;  4DR2 E;  4BA1 B;  4WUB A;  3M7N G;  2BR2 B;  4DR2 I;  4LF5 E;  4X64 I;  4JI7 E;  1MG7 A;  3J80 C;  4OO1 D;  4LF5 I;  3P3G A;  2BA0 D;  2E1R A;  2WP8 B;  2WNR A;  2F1D A;  1UDN A;  2C38 B;  4DR5 E;  1H7U A;  3ZZT A;  4NBQ A;  4DR5 I;  2HFU A;  4NXM E;  1Y60 A;  2CGE A;  4LF8 E;  4DR4 E;  4BA2 A;  4KHP E;  4NXM I;  2VF3 A;  4LF8 I;  4QNJ A;  5EKW A;  4IFD F;  2O1T A;  2Z5C A;  4KHP I;  1A6F A;  1H7S A;  2PO2 A;  2HFS A;  1ZXN A;  5C0X B;  2C39 B;  2UU9 E;  1FNM A;  4BA1 A;  4FW3 A;  3QT7 A;  1Y4S A;  1WUU A;  5LMN E;  1RHY A;  2ZBK B;  2BR2 A;  4DPY A;  1XMO E;  2UU9 I;  3ZZ0 A;  5GME A;  5LMN I;  1I94 E;  1XMO I;  1XNQ E;  2O3Z A;  4LF9 E;  1I94 I;  4IFD A;  1E3H A;  1XNQ I;  2WP8 A;  4B3S E;  4LF9 I;  3B78 A;  3M6A A;  3P3C A;  3H4L A;  4DUY E;  4B3S I;  2BA0 G;  3LNU A;  5C0X F;  2C38 A;  3V2U C;  3NZK A;  4DXL A;  1ZXM A;  4DUY I;  4AQY E;  4XTJ A;  4DV0 E;  2X36 A;  4MU0 A;  2NN6 C;  2ZM6 E;  1IBK E;  4AQY I;  4DV0 I;  3F0N A;  3H1C A;  2ZM6 I;  1J5E E;  3J7A G;  1IBK I;  2JE6 B;  1B63 A;  1HK7 A;  3PYD A;  1J5E I;  2BM0 A;  1D6T A;  3PRY A;  5JEA E;  2UXC E;  4U3D A;  4FWD A;  4JI2 E;  4DU8 A;  2V2Q A;  4IFD D;  4GKK E;  4MU1 A;  2X7I A;  4DUZ E;  4WUD A;  4JI2 I;  3GON A;  2UUA E;  5C0X A;  4Z7Y A;  4GKK I;  2C39 A;  4DUZ I;  5A2Q Q;  3Q6N A;  2UUA I;  4EMD A;  4JI4 E;  2E5L E;  3JAM Q;  4JI4 I;  5K36 E;  2E5L I;  1EA6 A;  2Z5B B;  4WUC A;  2J65 A;  4JG4 A;  4DPW A;  4FWG A;  4LFA E;  1Z0C A;  2Z5E A;  2O1V A;  3P3E A;  2UUB E;  1ELO A;  1R6M A;  4B3M E;  2PNL A;  4UTG A;  2A2D A;  2UUB I;  1VI7 A;  2VES A;  2EFG A;  1Z59 A;  1ZM2 A;  4LFB E;  5C0X D;  4B3M I;  4JI1 E;  5BR8 I;  3B82 A;  4LF4 E;  3B8H A;  2JE6 A;  4LFB I;  4JI1 I;  4PRX A;  2DEJ A;  2O1W A;  1Z0G A;  4JI3 E;  4P52 A;  1EI1 A;  1UDQ A;  1BKN A;  4X64 E;  2HHH E;  4JI3 I;  4DR7 E;  3PYE A;  3GLL A;  1FKA E;  2HHH I;  2HK3 A;  4LCF A;  4DR7 I;  1R6L A;  1FI4 A;  2O1U A;  4X66 E;  4OO1 E;  4FW4 A;  3PS1 A;  4DV7 E;  2PO0 B;  4PU9 A;  4X66 I;  1E3P A;  2C37 B;  4DV7 I;  2BA1 D;  4AIM A;  2HKJ A;  2Z5B A;  4JI0 E;  3P76 A;  2BV3 A;  1OJ4 A;  1Y5Y A;  1S16 A;  2NN6 B;  4JI0 I;  4HYM A;  3GME A;  1FWK A;  2J7K A;  2VQE E;  2F4V E;  5DRP A;  3B4T A;  2VQE I;  3V5R A;  3CDJ A;  3U1Y A;  2F4V I;  1XXE A;  3K85 A;  4K0K E;  4HXZ A;  1DAR A;  4DPX A;  4K0K I;  1OYP A;  1N34 E;  3PS2 A;  3QT8 A;  2NN6 F;  1N34 I;  1Z5A A;  2PNM A;  2AJ4 A;  4MDT A;  2PNZ B;  1Z5B A;  1IBM E;  4NXN E;  2UXD E;  3D4J A;  1PVG A;  2CZ9 A;  5IT9 Q;  4NXN I;  1IBM I;  2UXD I;  1N36 E;  2PO1 B;  4LCG A;  2PO0 A;  4LCH A;  1VIS A;  1N36 I;  4QNK A;  2C37 A;  2GS8 A;  4FWH A;  3Q6M A;  2GQ0 A;  5EL9 A;  3UHM A;  1Z0T A;  4FN5 A;  2HKE A;  2NN6 A;  4LOM A;  4DR3 E;  4X62 E;  4MYT A;  4J3D A;  5A2Q C;  4DV3 I;  1N32 I;  1Z5C A;  2OI2 A;  4X62 I;  4DR3 I;  1HNZ E;  3JAM C;  5DRR A;  3T1Y E;  4KQV A;  5JEA C;  4USM A;  2JEA B;  4IZJ B; 
#chains in the Genus database with same CATH homology
 4LCG A;  4FW7 A;  4U3D A;  5DRP A;  5DRQ A;  4LCH A;  4LCF A;  3U1Y A;  3P3E A;  1XXE A;  3P3G A;  2IES A;  4FW4 A;  3PS1 A;  3P3C A;  2GO3 A;  1YH8 A;  2GO4 A;  5DRO A;  2VES A;  3UHM A;  3PS3 A;  4MQY A;  3NZK A;  2JT2 A;  4OZE A;  3PS2 A;  1YHC A;  4FW5 A;  4J3D A;  3P76 A;  4FW3 A;  4IS9 A;  2IER A;  4MDT A;  4FW6 A;  4ISA A;  4U3B A;  5DRR A;  4OKG A;  2J65 A;  1P42 A;  2O3Z A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3NZKA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations