3P3C | Genus

Total Genus 86

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	86
sequence length	272
structure length	272
Chain Sequence	GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQKLTRDL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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reading 272 atoms

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272 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
source organism	Aquifex aeolicus
publication title	Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design. pubmed doi rcsb
molecule keywords	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus	86
structure length	272
sequence length	272
ec nomenclature	ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date	2010-10-04

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03331	LpxC	UDP-3-O-acyl N-acetylglycosamine deacetylase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.230.20	Alpha Beta	2-Layer Sandwich	Ribosomal Protein S5; domain 2	lpxc deacetylase, domain 1	3p3cA01
3.30.1700.10	Alpha Beta	2-Layer Sandwich	lpxc deacetylase, domain 1	lpxc deacetylase, domain 2	3p3cA02

4FW4A 4LCGA 4OKGA 2JT2A 4MQYA 5DRQA 3P3EA 3UHMA 4FW3A 2GO3A 2O3ZA 4ISAA 4LCFA 3PS1A 3U1YA 4IS9A 2IESA 4MDTA 4U3BA 1YH8A 4LCHA 4U3DA 3NZKA 1YHCA 3PS2A 4FW6A 3P3CA 5DRPA 3P3GA 1XXEA 3P76A 3PS3A 4OZEA 2J65A 1P42A 2GO4A 4J3DA 5DROA 2VESA 4FW7A 5DRRA 2IERA 4FW5A
chains in the Genus database with same CATH superfamily

4MYTA 2ZBKB 4MQYA 4DV3I 1PVGA 2PO2B 4MU4A 3PS1A 4DR1I 2PNZA 2O1VA 4IFDA 4LF8I 2HK2A 5C0XE 1PIEA 4P7AA 4JI0I 1UEKA 2GO4A 2ZITA 3QT8A 4IZJD 4FWDA 5JEAF 1UDOA 5K36E 4DUYI 2WNRA 2O3ZA 1HR0I 1KTVA 2UUCE 5IT9Q 2Z5EA 2V8PA 5A2QC 2A2DA 1EA6A 1PKPA 2EFGA 1N0UA 4DV5I 4NXMI 1IBME 2UXCE 4KHPI 3WU4A 2BM0A 4IFDB 2CZ9A 1ZXNA 1U2RA 1ZM4A 1I94E 1FJGE 2C39A 4FW4A 1RR9A 1USUA 2Z5BA 4DXLA 1Z0BA 1Y5YA 4JYAE 4LFAI 5IWAI 1RREA 4DV6E 4B3SI 2O1WA 3M85D 4K0KI 3HJCA 4LF5E 2IESA 2X7IA 4GQUA 4JI6E 5LMUI 1VISA 2V2QA 2NPFA 3K85A 1IBKI 4DPYA 4PU9A 4QNJA 3B82A 4FWGA 1UDSA 4HXZA 5JEAE 1IBLI 1N32E 3B78A 3ZZ0A 5EKWA 4DU8A 1H73A 2R3VA 1EI1A 4LF7E 1Z0VA 4RPFA 4M1KA 4DV7E 4MU3A 3WU6A 4X64E 4OKGA 2WP8B 3F0NA 1XHKA 4JG4A 4JI8I 5BR8E 4MU1A 4JI5E 3OTOI 4DPTA 3CWVA 2JEAA 4I3HA 4UT4A 2C38A 4LCHA 2UUBI 4OO1C 4JI2E 4JV5E 1NHIA 4B3RI 4LFBI 1KIJA 4OO1A 2VESA 4Z7CA 3J80C 5DRRA 2AE8A 3ZZUA 4DR5E 4LOMA 1N36E 2XEXA 4ED4A 2VQFE 2PO1A 3K17A 3GMEA 4QNKA 4U3DA 4R1FA 1Y4SA 2DEJA 4LF9I 4PRXA 2F4VI 4UTGA 2V2VA 1HNZI 2UXDE 1KKHA 3L7ZB 1XXEA 4X66I 2NN6C 1FWLA 4GKKI 1S16A 4AIMA 4DV2I 2JE6A 3T1YE 3M7NG 1FNMA 1D6TA 3K1JA 1KVKA 4WUDA 4DR2I 5DRQA 2NN6A 2OI2A 2BA0G 4LF6E 5K36C 4HACA 4JI7E 1XMQI 4IZJB 2PNMA 1ZM9A 3ZKDA 4IFDF 1H74A 2J7KA 3T1HI 4DR4E 3P3CA 2PO1B 4OO1D 3PS3A 3PYGA 3J81Q 4IZKB 5LMNI 3HKMA 1ZM3A 4YY3I 4P52A 1ZM2A 4LF8E 2BA1D 1QZRA 1OJ4A 4DR6E 2VQEI 1XMOI 4DR3I 4AM3A 4BA1A 4GKJI 1OYPA 3P3GA 5GMEA 4DV1I 1Z5CA 4DUYE 3H1CA 1MU5A 3P76A 2PNZB 1HR0E 1P42A 1RHYA 4LFCI 4EMDA 4LF4I 3QT6A 1Z0CA 5C0XD 4IFDE 2NN6D 2GQ0A 4HY1A 4DV5E 2HK3A 4AQYE 4JI4I 1XNRI 1Y4UA 3J7AM 4KHPE 3P06A 1FKAE 1Z0GA 1N34I 4OX9E 3U1YA 4IS9A 3WU3A 1FJGI 3PRYA 3LNUA 4X65E 2HFUA 1XNQE 5K36D 3ZZTA 2WNRB 4B3ME 1B62A 4YHHE 2ZM6I 4LFAE 4KQVA 2UUAI 3M6AA 4B3SE 1HNWE 4FW7A 5A2QQ 2E1RA 1IBKE 2UU9I 4FW5A 1IBLE 3LTOA 5FLXC 3H4LA 1HNXI 4LF7I 2C39B 1Z59A 2Z5BB 1Y60A 5BR8I 2IOQA 4DUZI 4JI8E 3QT7A 3KRNA 4XTJA 4OO1F 4JI3E 3OTOE 2J65A 2E5LI 3HULA 4JI1I 5JEAD 1E3HA 2O1UA 4MU0A 4JV5I 1OYRA 2HHHE 2CG9A 1Z0EA 2BR2A 4LFBE 4NXNI 4FW3A 2JEBA 4ISAA 1N0VC 1Z5BA 4Z7YA 4X62E 3NZKA 1YHCA 3B4TA 5L3JA 1ZXMA 1N33I 5FLXQ 4B3TE 1N36I 2JEAB 2C38B 2PO0A 4DR7I 4DV0E 5GMDA 5C0XC 4DPXA 3Q6NA 4DV4I 4LF9E 2NN6F 1J5EI 2AJ4A 2JT2A 4N3OA 5EL9A 2UXDI 3DD6A 1HNZE 5C0XA 4OO1B 1VI7A 4OO1E 1USVA 2PNLA 3J80Q 2UXBI 2BR2B 5K36F 1A6FA 3CDJA 1ELOA 5K36A 4DV3E 3D4JA 5IT9C 1XMQE 1B63A 1NZ0A 2WW4A 4WUCA 2IERA 4DR1E 4DR4I 3T1HE 2PO0B 1R6LA 1E3PA 3LPSA 4IFDC 1NHJA 2X36A 3M7ND 2JE6B 1Z0WA 3WU5A 4JI0E 3J7AG 5C0XB 1NHHA 5LMNE 1H72C 2NN6B 2IOPA 5FWKA 2BA0D 4YY3E 4FW6A 4DR6I 3GLLA 5DRPA 4HACB 2HKEA 1R6MA 2NN6E 4FN5A 2VQEE 1XMOE 4DPUA 5JEAC 2HFSA 5DNXA 2UUCI 4DR3E 3B8HA 5K36B 1WUUA 3M85G 4GKJE 3ZM7A 5JEAA 1BKNA 1IBMI 3GONA 2UXCI 1UDQA 4NXME 4DV1E 1FWKA 1Z5AA 2DEIA 4U3BA 4LFCE 2CVEA 4LF4E 3ZKBA 1I94I 4AQYI 4JYAI 1XNRE 4JI4E 2C37A 2WP8A 4DV6I 5IWAE 4OX9I 5DROA 3PYDA 1UDNA 4X65I 4BA1B 4LF5I 1N34E 3V5RA 1XNQI 4JI6I 4K0KE 5LMUE 2F1DA 4LCGA 1DARA 4B3MI 4YHHI 1N32I 2ZM6E 2Q2EB 2V2ZA 2UUAE 1HNWI 4USKA 1K47A 1Y6ZA 4IFDD 2V34A 4MDTA 5JEAB 4DV7I 2UU9E 4X64I 2Z5CA 3CDIA 1HK7A 4BA2A 4JI5I 3V2UC 1HNXE 4NBQA 3JAMC 2CGEA 1Z0TA 2R42A 3PYFA 4USMA 1MG7A 2C37B 4LPFA 2UUBE 4JI2I 4DUZE 4WUBA 4JI3I 3P3EA 4B3RE 3UHMA 5LL6R 4PRVA 4AIDA 1MX0A 3L7ZA 2E5LE 4JI1E 1S4EA 5DNLA 2HHHI 2O1TA 4NXNE 1H7UA 2VF3A 4DR5I 4OZEA 2VQFI 4MYUA 2Z5CB 4URLA 4X62I 4BA2B 2A2CA 2PO2A 3Q6MA 4IZJA 5C0XF 4ZVIA 2BM1A 4B3TI 2F4VE 3Q1QA 3PYEA 1N33E 3QT5A 2GO3A 4DV0I 1H7SA 4DR7E 3JAMQ 3J81C 4LCFA 3U1KA 4X66E 1YH8A 3T1YI 1OYSA 4GKKE 3PS2A 2GS8A 4IZKA 4DPWA 4DV2E 4DV4E 1J5EE 2BV3A 4DU7A 2JEBB 1FI4A 4FW9A 4DR2E 4LF6I 4FWHA 2HKJA 2BA1G 3GCMA 4JI7I 4J3DA 5ELWA 2UXBE 4HYMA 2LJPA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4FW4 A;  4LCG A;  4OKG A;  2JT2 A;  4MQY A;  5DRQ A;  3P3E A;  3UHM A;  4FW3 A;  2GO3 A;  2O3Z A;  4ISA A;  4LCF A;  3PS1 A;  3U1Y A;  4IS9 A;  2IES A;  4MDT A;  4U3B A;  1YH8 A;  4LCH A;  4U3D A;  3NZK A;  1YHC A;  3PS2 A;  4FW6 A;  3P3C A;  5DRP A;  3P3G A;  1XXE A;  3P76 A;  3PS3 A;  4OZE A;  2J65 A;  1P42 A;  2GO4 A;  4J3D A;  5DRO A;  2VES A;  4FW7 A;  5DRR A;  2IER A;  4FW5 A; 
#chains in the Genus database with same CATH topology
 4MYT A;  2ZBK B;  4MQY A;  4DV3 I;  1PVG A;  2PO2 B;  4MU4 A;  3PS1 A;  4DR1 I;  2PNZ A;  2O1V A;  4IFD A;  4LF8 I;  2HK2 A;  5C0X E;  1PIE A;  4P7A A;  4JI0 I;  1UEK A;  2GO4 A;  2ZIT A;  3QT8 A;  4IZJ D;  4FWD A;  5JEA F;  1UDO A;  5K36 E;  4DUY I;  2WNR A;  2O3Z A;  1HR0 I;  1KTV A;  2UUC E;  5IT9 Q;  2Z5E A;  2V8P A;  5A2Q C;  2A2D A;  1EA6 A;  1PKP A;  2EFG A;  1N0U A;  4DV5 I;  4NXM I;  1IBM E;  2UXC E;  4KHP I;  3WU4 A;  2BM0 A;  4IFD B;  2CZ9 A;  1ZXN A;  1U2R A;  1ZM4 A;  1I94 E;  1FJG E;  2C39 A;  4FW4 A;  1RR9 A;  1USU A;  2Z5B A;  4DXL A;  1Z0B A;  1Y5Y A;  4JYA E;  4LFA I;  5IWA I;  1RRE A;  4DV6 E;  4B3S I;  2O1W A;  3M85 D;  4K0K I;  3HJC A;  4LF5 E;  2IES A;  2X7I A;  4GQU A;  4JI6 E;  5LMU I;  1VIS A;  2V2Q A;  2NPF A;  3K85 A;  1IBK I;  4DPY A;  4PU9 A;  4QNJ A;  3B82 A;  4FWG A;  1UDS A;  4HXZ A;  5JEA E;  1IBL I;  1N32 E;  3B78 A;  3ZZ0 A;  5EKW A;  4DU8 A;  1H73 A;  2R3V A;  1EI1 A;  4LF7 E;  1Z0V A;  4RPF A;  4M1K A;  4DV7 E;  4MU3 A;  3WU6 A;  4X64 E;  4OKG A;  2WP8 B;  3F0N A;  1XHK A;  4JG4 A;  4JI8 I;  5BR8 E;  4MU1 A;  4JI5 E;  3OTO I;  4DPT A;  3CWV A;  2JEA A;  4I3H A;  4UT4 A;  2C38 A;  4LCH A;  2UUB I;  4OO1 C;  4JI2 E;  4JV5 E;  1NHI A;  4B3R I;  4LFB I;  1KIJ A;  4OO1 A;  2VES A;  4Z7C A;  3J80 C;  5DRR A;  2AE8 A;  3ZZU A;  4DR5 E;  4LOM A;  1N36 E;  2XEX A;  4ED4 A;  2VQF E;  2PO1 A;  3K17 A;  3GME A;  4QNK A;  4U3D A;  4R1F A;  1Y4S A;  2DEJ A;  4LF9 I;  4PRX A;  2F4V I;  4UTG A;  2V2V A;  1HNZ I;  2UXD E;  1KKH A;  3L7Z B;  1XXE A;  4X66 I;  2NN6 C;  1FWL A;  4GKK I;  1S16 A;  4AIM A;  4DV2 I;  2JE6 A;  3T1Y E;  3M7N G;  1FNM A;  1D6T A;  3K1J A;  1KVK A;  4WUD A;  4DR2 I;  5DRQ A;  2NN6 A;  2OI2 A;  2BA0 G;  4LF6 E;  5K36 C;  4HAC A;  4JI7 E;  1XMQ I;  4IZJ B;  2PNM A;  1ZM9 A;  3ZKD A;  4IFD F;  1H74 A;  2J7K A;  3T1H I;  4DR4 E;  3P3C A;  2PO1 B;  4OO1 D;  3PS3 A;  3PYG A;  3J81 Q;  4IZK B;  5LMN I;  3HKM A;  1ZM3 A;  4YY3 I;  4P52 A;  1ZM2 A;  4LF8 E;  2BA1 D;  1QZR A;  1OJ4 A;  4DR6 E;  2VQE I;  1XMO I;  4DR3 I;  4AM3 A;  4BA1 A;  4GKJ I;  1OYP A;  3P3G A;  5GME A;  4DV1 I;  1Z5C A;  4DUY E;  3H1C A;  1MU5 A;  3P76 A;  2PNZ B;  1HR0 E;  1P42 A;  1RHY A;  4LFC I;  4EMD A;  4LF4 I;  3QT6 A;  1Z0C A;  5C0X D;  4IFD E;  2NN6 D;  2GQ0 A;  4HY1 A;  4DV5 E;  2HK3 A;  4AQY E;  4JI4 I;  1XNR I;  1Y4U A;  3J7A M;  4KHP E;  3P06 A;  1FKA E;  1Z0G A;  1N34 I;  4OX9 E;  3U1Y A;  4IS9 A;  3WU3 A;  1FJG I;  3PRY A;  3LNU A;  4X65 E;  2HFU A;  1XNQ E;  5K36 D;  3ZZT A;  2WNR B;  4B3M E;  1B62 A;  4YHH E;  2ZM6 I;  4LFA E;  4KQV A;  2UUA I;  3M6A A;  4B3S E;  1HNW E;  4FW7 A;  5A2Q Q;  2E1R A;  1IBK E;  2UU9 I;  4FW5 A;  1IBL E;  3LTO A;  5FLX C;  3H4L A;  1HNX I;  4LF7 I;  2C39 B;  1Z59 A;  2Z5B B;  1Y60 A;  5BR8 I;  2IOQ A;  4DUZ I;  4JI8 E;  3QT7 A;  3KRN A;  4XTJ A;  4OO1 F;  4JI3 E;  3OTO E;  2J65 A;  2E5L I;  3HUL A;  4JI1 I;  5JEA D;  1E3H A;  2O1U A;  4MU0 A;  4JV5 I;  1OYR A;  2HHH E;  2CG9 A;  1Z0E A;  2BR2 A;  4LFB E;  4NXN I;  4FW3 A;  2JEB A;  4ISA A;  1N0V C;  1Z5B A;  4Z7Y A;  4X62 E;  3NZK A;  1YHC A;  3B4T A;  5L3J A;  1ZXM A;  1N33 I;  5FLX Q;  4B3T E;  1N36 I;  2JEA B;  2C38 B;  2PO0 A;  4DR7 I;  4DV0 E;  5GMD A;  5C0X C;  4DPX A;  3Q6N A;  4DV4 I;  4LF9 E;  2NN6 F;  1J5E I;  2AJ4 A;  2JT2 A;  4N3O A;  5EL9 A;  2UXD I;  3DD6 A;  1HNZ E;  5C0X A;  4OO1 B;  1VI7 A;  4OO1 E;  1USV A;  2PNL A;  3J80 Q;  2UXB I;  2BR2 B;  5K36 F;  1A6F A;  3CDJ A;  1ELO A;  5K36 A;  4DV3 E;  3D4J A;  5IT9 C;  1XMQ E;  1B63 A;  1NZ0 A;  2WW4 A;  4WUC A;  2IER A;  4DR1 E;  4DR4 I;  3T1H E;  2PO0 B;  1R6L A;  1E3P A;  3LPS A;  4IFD C;  1NHJ A;  2X36 A;  3M7N D;  2JE6 B;  1Z0W A;  3WU5 A;  4JI0 E;  3J7A G;  5C0X B;  1NHH A;  5LMN E;  1H72 C;  2NN6 B;  2IOP A;  5FWK A;  2BA0 D;  4YY3 E;  4FW6 A;  4DR6 I;  3GLL A;  5DRP A;  4HAC B;  2HKE A;  1R6M A;  2NN6 E;  4FN5 A;  2VQE E;  1XMO E;  4DPU A;  5JEA C;  2HFS A;  5DNX A;  2UUC I;  4DR3 E;  3B8H A;  5K36 B;  1WUU A;  3M85 G;  4GKJ E;  3ZM7 A;  5JEA A;  1BKN A;  1IBM I;  3GON A;  2UXC I;  1UDQ A;  4NXM E;  4DV1 E;  1FWK A;  1Z5A A;  2DEI A;  4U3B A;  4LFC E;  2CVE A;  4LF4 E;  3ZKB A;  1I94 I;  4AQY I;  4JYA I;  1XNR E;  4JI4 E;  2C37 A;  2WP8 A;  4DV6 I;  5IWA E;  4OX9 I;  5DRO A;  3PYD A;  1UDN A;  4X65 I;  4BA1 B;  4LF5 I;  1N34 E;  3V5R A;  1XNQ I;  4JI6 I;  4K0K E;  5LMU E;  2F1D A;  4LCG A;  1DAR A;  4B3M I;  4YHH I;  1N32 I;  2ZM6 E;  2Q2E B;  2V2Z A;  2UUA E;  1HNW I;  4USK A;  1K47 A;  1Y6Z A;  4IFD D;  2V34 A;  4MDT A;  5JEA B;  4DV7 I;  2UU9 E;  4X64 I;  2Z5C A;  3CDI A;  1HK7 A;  4BA2 A;  4JI5 I;  3V2U C;  1HNX E;  4NBQ A;  3JAM C;  2CGE A;  1Z0T A;  2R42 A;  3PYF A;  4USM A;  1MG7 A;  2C37 B;  4LPF A;  2UUB E;  4JI2 I;  4DUZ E;  4WUB A;  4JI3 I;  3P3E A;  4B3R E;  3UHM A;  5LL6 R;  4PRV A;  4AID A;  1MX0 A;  3L7Z A;  2E5L E;  4JI1 E;  1S4E A;  5DNL A;  2HHH I;  2O1T A;  4NXN E;  1H7U A;  2VF3 A;  4DR5 I;  4OZE A;  2VQF I;  4MYU A;  2Z5C B;  4URL A;  4X62 I;  4BA2 B;  2A2C A;  2PO2 A;  3Q6M A;  4IZJ A;  5C0X F;  4ZVI A;  2BM1 A;  4B3T I;  2F4V E;  3Q1Q A;  3PYE A;  1N33 E;  3QT5 A;  2GO3 A;  4DV0 I;  1H7S A;  4DR7 E;  3JAM Q;  3J81 C;  4LCF A;  3U1K A;  4X66 E;  1YH8 A;  3T1Y I;  1OYS A;  4GKK E;  3PS2 A;  2GS8 A;  4IZK A;  4DPW A;  4DV2 E;  4DV4 E;  1J5E E;  2BV3 A;  4DU7 A;  2JEB B;  1FI4 A;  4FW9 A;  4DR2 E;  4LF6 I;  4FWH A;  2HKJ A;  2BA1 G;  3GCM A;  4JI7 I;  4J3D A;  5ELW A;  2UXB E;  4HYM A;  2LJP A; 
#chains in the Genus database with same CATH homology
 4FW4 A;  4LCG A;  4OKG A;  2JT2 A;  4MQY A;  5DRQ A;  3P3E A;  3UHM A;  4FW3 A;  2GO3 A;  2O3Z A;  4ISA A;  4LCF A;  3PS1 A;  3U1Y A;  4IS9 A;  2IES A;  4MDT A;  4U3B A;  1YH8 A;  4LCH A;  4U3D A;  3NZK A;  1YHC A;  3PS2 A;  4FW6 A;  3P3C A;  5DRP A;  3P3G A;  1XXE A;  3P76 A;  3PS3 A;  4OZE A;  2J65 A;  1P42 A;  2GO4 A;  4J3D A;  5DRO A;  2VES A;  4FW7 A;  5DRR A;  2IER A;  4FW5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3P3CA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations