3P76 | Genus

Total Genus 91

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	91
sequence length	267
structure length	267
Chain Sequence	GLEKTVKEKLSFEGVGIHTGEYSKLIIHPEKEGTGIRFFKNGVYIPARHEFVVHTNHSTDLGFKGQRIKTVEHILSVLHLLEITNVTIEVIGNEIPILDGSGWEFYEAIRKNILNQNREIDYFVVEEPIIVEDEGRLIKAEPSDTLEVTYEGEFKNFLGRQKFTFVEGNEEEIVLARTFAFDWEIEHIKKVGLGKGGSLKNTLVLGKDKVYNPEGLRYENEPVRHKVFDLIGDLYLLGSPVKGKFYSFRGGHSLNVKLVKELAKKQK

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hydrolase
publication title	Design and synthesis of potent Gram-negative specific LpxC inhibitors. pubmed doi rcsb
molecule keywords	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus	91
structure length	267
sequence length	267
ec nomenclature	ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date	2010-10-12

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF03331	LpxC	UDP-3-O-acyl N-acetylglycosamine deacetylase

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.230.20	Alpha Beta	2-Layer Sandwich	Ribosomal Protein S5; domain 2	lpxc deacetylase, domain 1	3p76A01
3.30.1700.10	Alpha Beta	2-Layer Sandwich	lpxc deacetylase, domain 1	lpxc deacetylase, domain 2	3p76A02

4FW6A 2O3ZA 4LCGA 3U1YA 2IERA 4FW5A 3PS1A 2J65A 4U3BA 2JT2A 1YH8A 5DRQA 5DRRA 3P3EA 4FW3A 4ISAA 2IESA 3UHMA 1XXEA 1YHCA 1P42A 5DRPA 4FW7A 3PS3A 4U3DA 2GO3A 3NZKA 2VESA 4LCFA 4IS9A 4J3DA 4OZEA 5DROA 3PS2A 4LCHA 3P3GA 2GO4A 3P76A 4MDTA 3P3CA 4FW4A 4MQYA 4OKGA
chains in the Genus database with same CATH superfamily

1S16A 1UEKA 4LCGA 2BM0A 4DV5I 2E5LE 2IERA 5EKWA 4FW5A 4DR2E 3P3EA 1B62A 4WUBA 3ZZ0A 4JI6E 1PVGA 4AQYI 5DNXA 3WU3A 1XMOI 2DEIA 1N34I 4MU4A 5IT9C 3ZKBA 2F4VI 1UDSA 1VISA 1N36I 4MYUA 4JI0I 1HR0I 2UUBI 2UUAI 2C39A 3QT6A 1Z0BA 2WW4A 1Z5AA 4DR4I 4DR5I 4DR6I 2HKEA 3M85D 4FN5A 2PNLA 4GKKI 1USVA 5JEAD 1Y5YA 4DV6E 1RREA 4DUYI 4GKJI 5A2QQ 2JT2A 1IBKE 1N0VC 4FWDA 5BR8I 4LF4I 4I3HA 2BA0D 1I94E 4FW7A 4B3RE 2O1VA 4EMDA 1XNRE 4JI8I 2Z5CB 5K36B 5LMUE 2CZ9A 2R42A 1MU5A 1OYPA 4XTJA 5C0XF 3PRYA 2HK3A 1DARA 2PO2B 4JI3E 1XHKA 3U1YA 5K36C 5FLXC 1XNQI 2CGEA 1PIEA 2V8PA 4B3TE 1NZ0A 3CWVA 3J80Q 4DPYA 3B8HA 2HHHI 4IFDA 4NBQA 3CDIA 4IZKA 3LPSA 4NXMI 4OO1D 3HJCA 5K36E 1ELOA 1PKPA 4DV7I 5K36F 4MU1A 1UDOA 2Z5BA 5LMNE 5IWAI 2PO1B 4HXZA 3M7ND 2C37A 5JEAB 3WU4A 4DR1E 2PO0A 1FWLA 1H7SA 4LOMA 5JEAC 4JI4E 1H7UA 2VQEE 1A6FA 2V2VA 1IBME 3J80C 2BA0G 2JEAB 1YHCA 2BV3A 4AIDA 4P52A 4DV4E 1B63A 4N3OA 4PRVA 5JEAE 2C38A 3K17A 2UXCE 4JI2I 4JV5I 3Q6MA 2UXDE 4LFCE 5EL9A 1D6TA 2VQFI 4DV2E 3F0NA 4IFDB 2EFGA 4K0KE 4OO1B 4LF6I 4X65E 3WU5A 3H1CA 4IFDC 3Q1QA 4OO1C 3NZKA 4JI1I 4DUZE 2VESA 4LCFA 1HNXI 4J3DA 4LFAI 3M7NG 3OTOE 1ZXNA 4FWGA 3T1HE 4IFDE 4MQYA 4FW6A 4OO1E 1Z0WA 1J5EE 4OO1F 4DV0E 2WNRB 4DPWA 2JE6A 2E5LI 1Z0EA 4LF7E 1XMQE 4DR2I 3QT7A 4LF8E 2E1RA 2O1WA 4JI6I 4DR3E 2NN6A 1HK7A 2A2DA 1Z0CA 4FW9A 4ED4A 4MDTA 4NXNE 2AE8A 1HNZE 4B3ME 2ZM6E 4IZJA 4USKA 5DRRA 5GMDA 4HACB 2UU9E 5ELWA 4DV6I 3GMEA 2PNZA 2JEBB 3P06A 2UUCE 5DRPA 1RR9A 1IBKI 3K1JA 1N33E 4R1FA 1R6LA 3PYFA 3V2UC 1KVKA 1I94I 3LTOA 1R6MA 4BA2A 1MX0A 4B3RI 4QNJA 1VI7A 4HYMA 4MU3A 1XNRI 5LMUI 4X64E 3DD6A 4URLA 2HKJA 4YY3E 5DRQA 2WP8A 4DR7E 4DPXA 5A2QC 1OJ4A 3T1YE 4JI3I 1HNWE 5GMEA 4IFDD 4OX9E 2C39B 3PS3A 4B3TI 4B3SE 1Y4SA 2Q2EB 3J81Q 4LFBE 1N32E 2LJPA 4LPFA 3PYDA 5LMNI 3M85G 1UDNA 3B82A 3L7ZA 4M1KA 2V34A 4DR1I 4BA1A 1E3PA 4JI4I 4U3DA 2VQEI 1IBMI 3Q6NA 5JEAF 4QNKA 1Z5CA 3PYEA 4AM3A 3P3GA 3J81C 4WUDA 4JI5E 3P3CA 4DV4I 2WP8B 2HK2A 4KHPE 3KRNA 2UXCI 3GLLA 2UXDI 3PS1A 1E3HA 1U2RA 5LL6R 4LF5E 2DEJA 4IZKB 4LFCI 2Z5EA 3M6AA 1Z0TA 3J7AG 4JYAE 4DV2I 4AIMA 2Z5BB 3K85A 2X36A 4K0KI 4JI7E 3U1KA 2C37B 1FNMA 3HKMA 1RHYA 1IBLE 4X65I 2PO0B 2CVEA 4HY1A 4OZEA 4LF9E 3B4TA 3ZZUA 1Z5BA 4DU7A 4DUZI 2PNMA 4X62E 3HULA 4IFDF 1EA6A 5C0XA 2UXBE 2OI2A 4X66E 3OTOI 4DV3E 3T1HI 3ZM7A 4PRXA 4X62I 2GS8A 2X7IA 4DV1E 4YHHE 2V2QA 1J5EI 4DV0I 2C38B 1FJGE 2GO3A 4DV5E 1ZM4A 4IS9A 1Z0GA 2GQ0A 4LF7I 1XMQI 2NN6D 4LF8I 5K36A 3P76A 4WUCA 4UTGA 1Y6ZA 2IOPA 4AQYE 1OYRA 1XMOE 4DR3I 1N34E 2HFUA 2F4VE 2BA1D 2PO2A 1ZM9A 2R3VA 1H72C 1N36E 2UUBE 4JI0E 4NXNI 4IZJD 1HR0E 2UUAE 4FW3A 1EI1A 3PYGA 1HNZI 4B3MI 2ZM6I 1XXEA 3QT5A 4DR5E 4DR4E 4DR6E 2UU9I 4GKKE 1MG7A 4DUYE 3PS2A 4GKJE 5C0XB 2UUCI 3B78A 4P7AA 3H4LA 1UDQA 2PO1A 5FLXQ 5JEAA 5BR8E 1N33I 4LF4E 4RPFA 2JE6B 4Z7YA 5L3JA 5C0XC 4USMA 4KQVA 4JI8E 5DNLA 2ZITA 1S4EA 3CDJA 2A2CA 4DU8A 3QT8A 4X64I 1Y4UA 3GONA 4YY3I 2V2ZA 2ZBKB 2NN6B 4DR7I 3ZKDA 5C0XE 3T1YI 2JEAA 1HNWI 5DROA 1XNQE 4OX9I 1NHIA 2O1TA 1KKHA 3V5RA 4DXLA 1KTVA 2NN6C 4DPUA 4B3SI 2VF3A 2HHHE 2O3ZA 4IZJB 4NXME 2HFSA 4LFBI 3GCMA 4DV7E 1N32I 2PNZB 2BA1G 5FWKA 2IOQA 5IWAE 2NN6E 4OO1A 1H73A 2NN6F 4PU9A 1P42A 1Z0VA 4BA2B 2BR2A 3J7AM 1FKAE 1BKNA 1K47A 4MYTA 2NPFA 2GO4A 4JG4A 4FW4A 1ZM3A 3LNUA 3JAMQ 3D4JA 2J65A 1NHJA 1N0UA 1YH8A 4JI5I 1Y60A 4GQUA 4ISAA 4KHPI 2WNRA 4JI2E 4JV5E 2IESA 1OYSA 2F1DA 1FI4A 2AJ4A 4LF5I 1QZRA 4Z7CA 2VQFE 1ZM2A 4JYAI 2J7KA 4MU0A 4LCHA 4JI7I 2BM1A 4LF6E 3L7ZB 2CG9A 1KIJA 3JAMC 1IBLI 4BA1B 4LF9I 4FWHA 4U3BA 1Z59A 5C0XD 1NHHA 1ZXMA 1WUUA 4JI1E 3WU6A 2BR2B 1HNXE 5IT9Q 4LFAE 3UHMA 4HACA 2UXBI 4X66I 4DPTA 4ZVIA 2XEXA 4DV3I 1FWKA 2JEBA 4DV1I 3ZZTA 4YHHI 1USUA 2O1UA 1FJGI 4UT4A 2Z5CA 1H74A 5K36D 4OKGA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4FW6 A;  2O3Z A;  4LCG A;  3U1Y A;  2IER A;  4FW5 A;  3PS1 A;  2J65 A;  4U3B A;  2JT2 A;  1YH8 A;  5DRQ A;  5DRR A;  3P3E A;  4FW3 A;  4ISA A;  2IES A;  3UHM A;  1XXE A;  1YHC A;  1P42 A;  5DRP A;  4FW7 A;  3PS3 A;  4U3D A;  2GO3 A;  3NZK A;  2VES A;  4LCF A;  4IS9 A;  4J3D A;  4OZE A;  5DRO A;  3PS2 A;  4LCH A;  3P3G A;  2GO4 A;  3P76 A;  4MDT A;  3P3C A;  4FW4 A;  4MQY A;  4OKG A; 
#chains in the Genus database with same CATH topology
 1S16 A;  1UEK A;  4LCG A;  2BM0 A;  4DV5 I;  2E5L E;  2IER A;  5EKW A;  4FW5 A;  4DR2 E;  3P3E A;  1B62 A;  4WUB A;  3ZZ0 A;  4JI6 E;  1PVG A;  4AQY I;  5DNX A;  3WU3 A;  1XMO I;  2DEI A;  1N34 I;  4MU4 A;  5IT9 C;  3ZKB A;  2F4V I;  1UDS A;  1VIS A;  1N36 I;  4MYU A;  4JI0 I;  1HR0 I;  2UUB I;  2UUA I;  2C39 A;  3QT6 A;  1Z0B A;  2WW4 A;  1Z5A A;  4DR4 I;  4DR5 I;  4DR6 I;  2HKE A;  3M85 D;  4FN5 A;  2PNL A;  4GKK I;  1USV A;  5JEA D;  1Y5Y A;  4DV6 E;  1RRE A;  4DUY I;  4GKJ I;  5A2Q Q;  2JT2 A;  1IBK E;  1N0V C;  4FWD A;  5BR8 I;  4LF4 I;  4I3H A;  2BA0 D;  1I94 E;  4FW7 A;  4B3R E;  2O1V A;  4EMD A;  1XNR E;  4JI8 I;  2Z5C B;  5K36 B;  5LMU E;  2CZ9 A;  2R42 A;  1MU5 A;  1OYP A;  4XTJ A;  5C0X F;  3PRY A;  2HK3 A;  1DAR A;  2PO2 B;  4JI3 E;  1XHK A;  3U1Y A;  5K36 C;  5FLX C;  1XNQ I;  2CGE A;  1PIE A;  2V8P A;  4B3T E;  1NZ0 A;  3CWV A;  3J80 Q;  4DPY A;  3B8H A;  2HHH I;  4IFD A;  4NBQ A;  3CDI A;  4IZK A;  3LPS A;  4NXM I;  4OO1 D;  3HJC A;  5K36 E;  1ELO A;  1PKP A;  4DV7 I;  5K36 F;  4MU1 A;  1UDO A;  2Z5B A;  5LMN E;  5IWA I;  2PO1 B;  4HXZ A;  3M7N D;  2C37 A;  5JEA B;  3WU4 A;  4DR1 E;  2PO0 A;  1FWL A;  1H7S A;  4LOM A;  5JEA C;  4JI4 E;  1H7U A;  2VQE E;  1A6F A;  2V2V A;  1IBM E;  3J80 C;  2BA0 G;  2JEA B;  1YHC A;  2BV3 A;  4AID A;  4P52 A;  4DV4 E;  1B63 A;  4N3O A;  4PRV A;  5JEA E;  2C38 A;  3K17 A;  2UXC E;  4JI2 I;  4JV5 I;  3Q6M A;  2UXD E;  4LFC E;  5EL9 A;  1D6T A;  2VQF I;  4DV2 E;  3F0N A;  4IFD B;  2EFG A;  4K0K E;  4OO1 B;  4LF6 I;  4X65 E;  3WU5 A;  3H1C A;  4IFD C;  3Q1Q A;  4OO1 C;  3NZK A;  4JI1 I;  4DUZ E;  2VES A;  4LCF A;  1HNX I;  4J3D A;  4LFA I;  3M7N G;  3OTO E;  1ZXN A;  4FWG A;  3T1H E;  4IFD E;  4MQY A;  4FW6 A;  4OO1 E;  1Z0W A;  1J5E E;  4OO1 F;  4DV0 E;  2WNR B;  4DPW A;  2JE6 A;  2E5L I;  1Z0E A;  4LF7 E;  1XMQ E;  4DR2 I;  3QT7 A;  4LF8 E;  2E1R A;  2O1W A;  4JI6 I;  4DR3 E;  2NN6 A;  1HK7 A;  2A2D A;  1Z0C A;  4FW9 A;  4ED4 A;  4MDT A;  4NXN E;  2AE8 A;  1HNZ E;  4B3M E;  2ZM6 E;  4IZJ A;  4USK A;  5DRR A;  5GMD A;  4HAC B;  2UU9 E;  5ELW A;  4DV6 I;  3GME A;  2PNZ A;  2JEB B;  3P06 A;  2UUC E;  5DRP A;  1RR9 A;  1IBK I;  3K1J A;  1N33 E;  4R1F A;  1R6L A;  3PYF A;  3V2U C;  1KVK A;  1I94 I;  3LTO A;  1R6M A;  4BA2 A;  1MX0 A;  4B3R I;  4QNJ A;  1VI7 A;  4HYM A;  4MU3 A;  1XNR I;  5LMU I;  4X64 E;  3DD6 A;  4URL A;  2HKJ A;  4YY3 E;  5DRQ A;  2WP8 A;  4DR7 E;  4DPX A;  5A2Q C;  1OJ4 A;  3T1Y E;  4JI3 I;  1HNW E;  5GME A;  4IFD D;  4OX9 E;  2C39 B;  3PS3 A;  4B3T I;  4B3S E;  1Y4S A;  2Q2E B;  3J81 Q;  4LFB E;  1N32 E;  2LJP A;  4LPF A;  3PYD A;  5LMN I;  3M85 G;  1UDN A;  3B82 A;  3L7Z A;  4M1K A;  2V34 A;  4DR1 I;  4BA1 A;  1E3P A;  4JI4 I;  4U3D A;  2VQE I;  1IBM I;  3Q6N A;  5JEA F;  4QNK A;  1Z5C A;  3PYE A;  4AM3 A;  3P3G A;  3J81 C;  4WUD A;  4JI5 E;  3P3C A;  4DV4 I;  2WP8 B;  2HK2 A;  4KHP E;  3KRN A;  2UXC I;  3GLL A;  2UXD I;  3PS1 A;  1E3H A;  1U2R A;  5LL6 R;  4LF5 E;  2DEJ A;  4IZK B;  4LFC I;  2Z5E A;  3M6A A;  1Z0T A;  3J7A G;  4JYA E;  4DV2 I;  4AIM A;  2Z5B B;  3K85 A;  2X36 A;  4K0K I;  4JI7 E;  3U1K A;  2C37 B;  1FNM A;  3HKM A;  1RHY A;  1IBL E;  4X65 I;  2PO0 B;  2CVE A;  4HY1 A;  4OZE A;  4LF9 E;  3B4T A;  3ZZU A;  1Z5B A;  4DU7 A;  4DUZ I;  2PNM A;  4X62 E;  3HUL A;  4IFD F;  1EA6 A;  5C0X A;  2UXB E;  2OI2 A;  4X66 E;  3OTO I;  4DV3 E;  3T1H I;  3ZM7 A;  4PRX A;  4X62 I;  2GS8 A;  2X7I A;  4DV1 E;  4YHH E;  2V2Q A;  1J5E I;  4DV0 I;  2C38 B;  1FJG E;  2GO3 A;  4DV5 E;  1ZM4 A;  4IS9 A;  1Z0G A;  2GQ0 A;  4LF7 I;  1XMQ I;  2NN6 D;  4LF8 I;  5K36 A;  3P76 A;  4WUC A;  4UTG A;  1Y6Z A;  2IOP A;  4AQY E;  1OYR A;  1XMO E;  4DR3 I;  1N34 E;  2HFU A;  2F4V E;  2BA1 D;  2PO2 A;  1ZM9 A;  2R3V A;  1H72 C;  1N36 E;  2UUB E;  4JI0 E;  4NXN I;  4IZJ D;  1HR0 E;  2UUA E;  4FW3 A;  1EI1 A;  3PYG A;  1HNZ I;  4B3M I;  2ZM6 I;  1XXE A;  3QT5 A;  4DR5 E;  4DR4 E;  4DR6 E;  2UU9 I;  4GKK E;  1MG7 A;  4DUY E;  3PS2 A;  4GKJ E;  5C0X B;  2UUC I;  3B78 A;  4P7A A;  3H4L A;  1UDQ A;  2PO1 A;  5FLX Q;  5JEA A;  5BR8 E;  1N33 I;  4LF4 E;  4RPF A;  2JE6 B;  4Z7Y A;  5L3J A;  5C0X C;  4USM A;  4KQV A;  4JI8 E;  5DNL A;  2ZIT A;  1S4E A;  3CDJ A;  2A2C A;  4DU8 A;  3QT8 A;  4X64 I;  1Y4U A;  3GON A;  4YY3 I;  2V2Z A;  2ZBK B;  2NN6 B;  4DR7 I;  3ZKD A;  5C0X E;  3T1Y I;  2JEA A;  1HNW I;  5DRO A;  1XNQ E;  4OX9 I;  1NHI A;  2O1T A;  1KKH A;  3V5R A;  4DXL A;  1KTV A;  2NN6 C;  4DPU A;  4B3S I;  2VF3 A;  2HHH E;  2O3Z A;  4IZJ B;  4NXM E;  2HFS A;  4LFB I;  3GCM A;  4DV7 E;  1N32 I;  2PNZ B;  2BA1 G;  5FWK A;  2IOQ A;  5IWA E;  2NN6 E;  4OO1 A;  1H73 A;  2NN6 F;  4PU9 A;  1P42 A;  1Z0V A;  4BA2 B;  2BR2 A;  3J7A M;  1FKA E;  1BKN A;  1K47 A;  4MYT A;  2NPF A;  2GO4 A;  4JG4 A;  4FW4 A;  1ZM3 A;  3LNU A;  3JAM Q;  3D4J A;  2J65 A;  1NHJ A;  1N0U A;  1YH8 A;  4JI5 I;  1Y60 A;  4GQU A;  4ISA A;  4KHP I;  2WNR A;  4JI2 E;  4JV5 E;  2IES A;  1OYS A;  2F1D A;  1FI4 A;  2AJ4 A;  4LF5 I;  1QZR A;  4Z7C A;  2VQF E;  1ZM2 A;  4JYA I;  2J7K A;  4MU0 A;  4LCH A;  4JI7 I;  2BM1 A;  4LF6 E;  3L7Z B;  2CG9 A;  1KIJ A;  3JAM C;  1IBL I;  4BA1 B;  4LF9 I;  4FWH A;  4U3B A;  1Z59 A;  5C0X D;  1NHH A;  1ZXM A;  1WUU A;  4JI1 E;  3WU6 A;  2BR2 B;  1HNX E;  5IT9 Q;  4LFA E;  3UHM A;  4HAC A;  2UXB I;  4X66 I;  4DPT A;  4ZVI A;  2XEX A;  4DV3 I;  1FWK A;  2JEB A;  4DV1 I;  3ZZT A;  4YHH I;  1USU A;  2O1U A;  1FJG I;  4UT4 A;  2Z5C A;  1H74 A;  5K36 D;  4OKG A; 
#chains in the Genus database with same CATH homology
 4FW6 A;  2O3Z A;  4LCG A;  3U1Y A;  2IER A;  4FW5 A;  3PS1 A;  2J65 A;  4U3B A;  2JT2 A;  1YH8 A;  5DRQ A;  5DRR A;  3P3E A;  4FW3 A;  4ISA A;  2IES A;  3UHM A;  1XXE A;  1YHC A;  1P42 A;  5DRP A;  4FW7 A;  3PS3 A;  4U3D A;  2GO3 A;  3NZK A;  2VES A;  4LCF A;  4IS9 A;  4J3D A;  4OZE A;  5DRO A;  3PS2 A;  4LCH A;  3P3G A;  2GO4 A;  3P76 A;  4MDT A;  3P3C A;  4FW4 A;  4MQY A;  4OKG A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3P76A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations