The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
30
|
sequence length |
160
|
structure length |
160
|
Chain Sequence |
LGVPFFSCQRGYKGVWRGDGIMQTTCPCGAQITGHVKNGSMRIVGPRTCSNTWHGTFPINAYTTGPCTPSPAPNYSRALWRVAAEEYVEVTRVGDFHYVTGMTTDNVKCPCQVPAPEFFTEVDGVRLHRYAPACKPLLREEVTFLVGLNQYLVGSQLPCE
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Crystal structure of a novel dimeric form of NS5A domain I protein from hepatitis C virus
pubmed doi rcsb |
| molecule tags |
Metal binding protein
|
| source organism |
Hepatitis c virus (isolate con1)
|
| molecule keywords |
Non-structural protein 5A
|
| total genus |
30
|
| structure length |
160
|
| sequence length |
160
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
2.7.7.48: RNA-directed RNA polymerase. |
| pdb deposition date | 2009-01-07 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF08300 | HCV_NS5a_1a | Hepatitis C virus non-structural 5a zinc finger domain |
| A | PF08301 | HCV_NS5a_1b | Hepatitis C virus non-structural 5a domain 1b |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Single Sheet | N-terminal domain of TfIIb | N-terminal domain of TfIIb | ||
| Mainly Beta | Single Sheet | N-terminal domain of TfIIb | N-terminal domain of TfIIb |
#chains in the Genus database with same CATH superfamily 4CL1 A; 3FQM A; 3FQQ A; 1ZH1 A; #chains in the Genus database with same CATH topology 3G71 Z; 5IP9 I; 3CC7 1; 4NBE A; 1S72 1; 1K9M 2; 2JIQ A; 1ZB8 A; 3MON A; 5A2Q b; 4HGZ A; 2LEX A; 2R6M A; 2IV2 X; 2W04 A; 3CXC Z; 1NJI 2; 1K8A 1; 2WAQ A; 4A3E I; 2EGT A; 3HOV I; 3GTM S; 1N2F A; 3CMA 1; 3I4M I; 3S2D I; 2OTJ 1; 1L1O C; 1VQK 1; 3IX0 A; 4TNU A; 2G2K A; 3S14 I; 3BG1 B; 4RVD A; 1KQS Y; 3JAM b; 3GTQ I; 1Q82 2; 2JIR A; 3G4S 1; 3GKQ A; 3QWU A; 3CCU Z; 3G71 1; 2GTI A; 1VQL 1; 2R7Z I; 4BY7 I; 1Z03 A; 3CD6 Z; 3VMG A; 1TFI A; 1VQN Z; 4RS4 A; 3K7A I; 4RVG A; 3CCM Z; 4E2X A; 4HH4 A; 3M4O I; 1I3Q I; 3CCQ Z; 5D1O B; 3GTL I; 4E33 A; 3G6E Z; 2RBL A; 3IF8 A; 4BBS I; 1FDI A; 1VQ9 Z; 2E2J I; 2JR6 A; 3S15 I; 3KIH A; 1SFO I; 3BG0 B; 4NB9 A; 3CCU 1; 3MZL B; 2I3C A; 1RO0 A; 2JIP A; 3P5J B; 4NH1 C; 5T64 A; 4NB8 A; 2JS4 A; 1VQ4 Z; 2Q51 A; 1VQN 1; 4A3L I; 1VQ5 Z; 1SIW A; 2OOY B; 1Y8C A; 2PK7 A; 2V45 A; 2JUB A; 1WJ2 A; 3G6E 1; 4MD7 A; 2DE5 A; 4BXX I; 1X3W A; 5D1P A; 2QRD B; 1VQ9 1; 1TWG I; 2LIY A; 3Q87 A; 4Y52 I; 3D6W A; 2M48 A; 2K5R A; 4NBC A; 3CPW Y; 2VPZ A; 4MH4 A; 2WB1 A; 2V8J A; 3NH4 A; 3GTJ I; 1FDO A; 2OTJ Z; 2HF1 A; 3ESW A; 5FLM I; 1YJ9 Z; 3CPW Z; 2JA6 I; 1VQK Z; 3J7A 4; 1KRL A; 4MON A; 1USP A; 1VQ5 1; 4DGL A; 1VQP 1; 4BY1 I; 4CL1 A; 3G4S Z; 1WCM I; 1K8A 2; 3RZD I; 3RZO I; 3EED A; 5FLX f; 1YUK A; 4E2W A; 1VQL Z; 3PO2 I; 2KPI A; 1ZB9 A; 3IR7 A; 3HOX I; 3CXC Y; 4A3D I; 5T6B A; 2V8I A; 2VUM I; 1X3Z A; 2NAP A; 3F3P C; 1P9N A; 1RO2 A; 2E2I I; 4NBF A; 2JA7 I; 3NH5 A; 3VMI A; 1Y1W I; 3VTN A; 2P3Y A; 2DE6 A; 4RVF A; 1YJ9 1; 1Z02 A; 4XX2 A; 1W2B Y; 3GCF A; 3CQZ I; 3J80 b; 2NVX I; 2QR1 B; 2F4M A; 5CM2 M; 2QKD A; 3J81 b; 3D2L A; 1VQ7 1; 3GTK I; 1W2B Z; 3S16 I; 4A3F I; 1K73 1; 1Q16 A; 1WZN A; 2Y0S A; 4E30 A; 1VQ6 Z; 3PO3 I; 5AN9 F; 1Z01 A; 3CCE 1; 1NP6 A; 3EER A; 2O4H A; 4NOZ A; 2YU9 I; 2JMO A; 1LQL A; 5A2Q f; 1S7M A; 2IZ4 A; 2E7Z A; 1VLA A; 2B63 I; 5C4X I; 2OTL 1; 1YHQ Z; 1M90 1; 4RVH A; 2RPR A; 2R92 I; 3S1Q I; 2QEX 1; 3JAM f; 2PMZ A; 1VQ6 1; 5T67 A; 4MRI A; 4Y7N I; 3S1M I; 2JIO A; 2JA8 I; 3IFU A; 1VQP Z; 5IT9 b; 2E9H A; 1YI2 Z; 3CC4 1; 2PM9 A; 3CCL 1; 1KD1 1; 1Q7Y 1; 2M6N A; 1RO4 A; 2GU2 A; 3H3V J; 4E32 A; 4NFR A; 2E2H I; 1VQ8 Z; 3GTP I; 1YHQ 1; 4S1T A; 1Q86 1; 2K3R A; 1QYP A; 3CCJ 1; 3HOY I; 3NH8 A; 4E2Z A; 4X6A I; 2HU9 A; 3HOW I; 1VQM Z; 1TWC I; 1TWH I; 1QVF Y; 2NVT I; 3U50 C; 3LUS A; 3M3Y I; 2O53 A; 3TE5 B; 3CME Z; 2VPW A; 3VMH A; 3I55 1; 4QTT A; 1VQ7 Z; 1YI2 1; 1QVF Z; 5C3E I; 3GTG I; 4MD8 A; 5D1O A; 3KIF A; 1Q81 1; 3D9X A; 2LFU A; 2OOX B; 3CC2 Z; 1QVG Z; 3CCS Z; 1YIJ 1; 3CCR Z; 4DK1 A; 2W03 A; 2RIQ A; 1VQ8 1; 1X0T A; 1DL6 A; 3I4N I; 4E2Y A; 2IZ3 A; 1AA6 A; 5LL6 f; 1YJN Z; 1N8R 1; 3CCE Z; 1M1K 1; 1WII A; 2AYD A; 1NUI A; 3NDJ A; 1VQM 1; 1KC8 1; 4DQY B; 2V8K A; 1K73 2; 1ML8 A; 2VUG A; 4QTU A; 1VQO Z; 3PO3 S; 3CME 1; 4A3C I; 2OTL Z; 1TWF I; 3HKZ A; 2QRC B; 3H0G I; 2NVY I; 2YAD A; 3VB9 A; 3CC2 1; 4HGY A; 3CCS 1; 1K9M 1; 3CCR 1; 2QEX Z; 2QA4 Z; 4A3J I; 4MD9 A; 1R9T I; 2VPY A; 3T4N B; 1YJN 1; 3FQQ A; 1M90 2; 2JA5 I; 3S1N I; 2GTH A; 1K83 I; 3CC4 Z; 1NJI 1; 3CCL Z; 2VPX A; 3HOU I; 2H85 A; 1QF8 A; 1KQS Z; 1VQO 1; 3GTM I; 2QRE B; 4AYB A; 1YJW Z; 1USP B; 1ZH1 A; 1Q82 1; 3CCJ Z; 3I56 Z; 1RQF A; 4RV9 A; 1KD1 2; 4MXU A; 1Q7Y 2; 4A3I I; 3J80 f; 3FKI I; 3S17 I; 2RHB A; 4NBH A; 3J81 f; 2QA4 1; 1PFT A; 3CCV Z; 1JWH C; 4E31 A; 5IP7 I; 1I6H I; 3I55 Z; 2P28 A; 1Q86 2; 1YUA A; 3NFZ A; 2VF1 A; 3MZK B; 3CD6 1; 1YIT Z; 2R93 I; 1RLY A; 4NBA A; 4A93 I; 2QLV B; 1WW9 A; 1YIJ Z; 3I07 A; 3TDH B; 5FLX b; 1YJW 1; 2DE7 A; 5C44 I; 2J6A A; 2JIM A; 4NBB A; 3OW2 Y; 2KI7 B; 4A3M I; 3CCM 1; 4BBR I; 2Q4Z A; 3GTO I; 4EWC A; 3I56 1; 3CCQ 1; 3S2H I; 1Q81 2; 1RNI A; 3NDI A; 3OW2 Z; 3CC7 Z; 1S72 Z; 2RT9 A; 3FQM A; 1Y1V S; 3CCV 1; 5C4J I; 1JJ2 Y; 4A3B I; 1QVG Y; 4A3G I; 3F3F C; 2NVQ I; 3HOZ I; 1N8R 2; 1M1K 2; 3S1R I; 1I50 I; 1KC8 2; 1QXF A; 2BJO A; 1YIT 1; 1TWA I; 1JJ2 Z; 4A3K I; 4NBD A; 3CMA Z; 2ZAE B; 5IT9 f; 1VQ4 1; 2OZK A; 2V3V A; 1Y1V I; 4NBG A; 2AKL A; 2F4O A; 2JNY A; #chains in the Genus database with same CATH homology 3G71 Z; 5IP9 I; 3CC7 1; 4NBE A; 1S72 1; 1K9M 2; 1ZB8 A; 3MON A; 5A2Q b; 4HGZ A; 2R6M A; 2W04 A; 3CXC Z; 1NJI 2; 1K8A 1; 2WAQ A; 4A3E I; 2EGT A; 3HOV I; 3GTM S; 1N2F A; 3CMA 1; 3I4M I; 3S2D I; 2OTJ 1; 1L1O C; 1VQK 1; 3IX0 A; 4TNU A; 2G2K A; 3S14 I; 3BG1 B; 4RVD A; 1KQS Y; 3JAM b; 3GTQ I; 1Q82 2; 3G4S 1; 3GKQ A; 3QWU A; 3CCU Z; 3G71 1; 2GTI A; 1VQL 1; 2R7Z I; 4BY7 I; 1Z03 A; 3CD6 Z; 3VMG A; 1TFI A; 1VQN Z; 4RS4 A; 3K7A I; 4RVG A; 3CCM Z; 4E2X A; 4HH4 A; 3M4O I; 1I3Q I; 3CCQ Z; 5D1O B; 3GTL I; 4E33 A; 3G6E Z; 2RBL A; 3IF8 A; 4BBS I; 1VQ9 Z; 2E2J I; 2JR6 A; 3S15 I; 3KIH A; 1SFO I; 3BG0 B; 4NB9 A; 3CCU 1; 3MZL B; 2I3C A; 1RO0 A; 3P5J B; 4NH1 C; 5T64 A; 4NB8 A; 2JS4 A; 1VQ4 Z; 2Q51 A; 1VQN 1; 4A3L I; 1VQ5 Z; 2OOY B; 2PK7 A; 2JUB A; 3G6E 1; 4MD7 A; 2DE5 A; 4BXX I; 1X3W A; 5D1P A; 2QRD B; 1VQ9 1; 1TWG I; 2LIY A; 3Q87 A; 4Y52 I; 3D6W A; 2M48 A; 2K5R A; 4NBC A; 3CPW Y; 4MH4 A; 2WB1 A; 2V8J A; 3NH4 A; 3GTJ I; 2OTJ Z; 2HF1 A; 3ESW A; 5FLM I; 1YJ9 Z; 3CPW Z; 2JA6 I; 1VQK Z; 3J7A 4; 1KRL A; 4MON A; 1USP A; 1VQ5 1; 4DGL A; 1VQP 1; 4BY1 I; 4CL1 A; 3G4S Z; 1WCM I; 1K8A 2; 3RZD I; 3RZO I; 3EED A; 5FLX f; 1YUK A; 4E2W A; 1VQL Z; 3PO2 I; 2KPI A; 1ZB9 A; 3HOX I; 3CXC Y; 4A3D I; 5T6B A; 2V8I A; 2VUM I; 1X3Z A; 3F3P C; 1P9N A; 1RO2 A; 2E2I I; 4NBF A; 2JA7 I; 3NH5 A; 3VMI A; 1Y1W I; 3VTN A; 2P3Y A; 2DE6 A; 4RVF A; 1YJ9 1; 1Z02 A; 4XX2 A; 1W2B Y; 3GCF A; 3CQZ I; 3J80 b; 2NVX I; 2QR1 B; 2F4M A; 5CM2 M; 2QKD A; 3J81 b; 1VQ7 1; 3GTK I; 1W2B Z; 3S16 I; 4A3F I; 1K73 1; 2Y0S A; 4E30 A; 1VQ6 Z; 3PO3 I; 5AN9 F; 1Z01 A; 3CCE 1; 1NP6 A; 3EER A; 2O4H A; 4NOZ A; 2YU9 I; 2JMO A; 1LQL A; 5A2Q f; 1S7M A; 2IZ4 A; 1VLA A; 2B63 I; 5C4X I; 2OTL 1; 1YHQ Z; 1M90 1; 4RVH A; 2RPR A; 2R92 I; 3S1Q I; 2QEX 1; 3JAM f; 2PMZ A; 1VQ6 1; 5T67 A; 4MRI A; 4Y7N I; 3S1M I; 2JA8 I; 3IFU A; 1VQP Z; 5IT9 b; 2E9H A; 1YI2 Z; 3CC4 1; 2PM9 A; 3CCL 1; 1KD1 1; 1Q7Y 1; 2M6N A; 1RO4 A; 2GU2 A; 3H3V J; 4E32 A; 4NFR A; 2E2H I; 1VQ8 Z; 3GTP I; 1YHQ 1; 4S1T A; 1Q86 1; 2K3R A; 1QYP A; 3CCJ 1; 3HOY I; 3NH8 A; 4E2Z A; 4X6A I; 2HU9 A; 3HOW I; 1VQM Z; 1TWC I; 1TWH I; 1QVF Y; 2NVT I; 3U50 C; 3LUS A; 3M3Y I; 2O53 A; 3TE5 B; 3CME Z; 3VMH A; 3I55 1; 4QTT A; 1VQ7 Z; 1YI2 1; 1QVF Z; 5C3E I; 3GTG I; 4MD8 A; 5D1O A; 3KIF A; 1Q81 1; 3D9X A; 2LFU A; 2OOX B; 3CC2 Z; 1QVG Z; 3CCS Z; 1YIJ 1; 3CCR Z; 4DK1 A; 2W03 A; 2RIQ A; 1VQ8 1; 1X0T A; 1DL6 A; 3I4N I; 4E2Y A; 2IZ3 A; 5LL6 f; 1YJN Z; 1N8R 1; 3CCE Z; 1M1K 1; 1WII A; 1NUI A; 3NDJ A; 1VQM 1; 1KC8 1; 4DQY B; 2V8K A; 1K73 2; 1ML8 A; 2VUG A; 4QTU A; 1VQO Z; 3PO3 S; 3CME 1; 4A3C I; 2OTL Z; 1TWF I; 3HKZ A; 2QRC B; 3H0G I; 2NVY I; 2YAD A; 3VB9 A; 3CC2 1; 4HGY A; 3CCS 1; 1K9M 1; 3CCR 1; 2QEX Z; 2QA4 Z; 4A3J I; 4MD9 A; 1R9T I; 3T4N B; 1YJN 1; 3FQQ A; 1M90 2; 2JA5 I; 3S1N I; 2GTH A; 1K83 I; 3CC4 Z; 1NJI 1; 3CCL Z; 3HOU I; 2H85 A; 1QF8 A; 1KQS Z; 1VQO 1; 3GTM I; 2QRE B; 4AYB A; 1YJW Z; 1USP B; 1ZH1 A; 1Q82 1; 3CCJ Z; 3I56 Z; 1RQF A; 4RV9 A; 1KD1 2; 4MXU A; 1Q7Y 2; 4A3I I; 3J80 f; 3FKI I; 3S17 I; 2RHB A; 4NBH A; 3J81 f; 2QA4 1; 1PFT A; 3CCV Z; 1JWH C; 4E31 A; 5IP7 I; 1I6H I; 3I55 Z; 2P28 A; 1Q86 2; 1YUA A; 3NFZ A; 2VF1 A; 3MZK B; 3CD6 1; 1YIT Z; 2R93 I; 1RLY A; 4NBA A; 4A93 I; 2QLV B; 1WW9 A; 1YIJ Z; 3I07 A; 3TDH B; 5FLX b; 1YJW 1; 2DE7 A; 5C44 I; 2J6A A; 4NBB A; 3OW2 Y; 2KI7 B; 4A3M I; 3CCM 1; 4BBR I; 2Q4Z A; 3GTO I; 4EWC A; 3I56 1; 3CCQ 1; 3S2H I; 1Q81 2; 1RNI A; 3NDI A; 3OW2 Z; 3CC7 Z; 1S72 Z; 2RT9 A; 3FQM A; 1Y1V S; 3CCV 1; 5C4J I; 1JJ2 Y; 4A3B I; 1QVG Y; 4A3G I; 3F3F C; 2NVQ I; 3HOZ I; 1N8R 2; 1M1K 2; 3S1R I; 1I50 I; 1KC8 2; 2BJO A; 1YIT 1; 1TWA I; 1JJ2 Z; 4A3K I; 4NBD A; 3CMA Z; 2ZAE B; 5IT9 f; 1VQ4 1; 2OZK A; 1Y1V I; 4NBG A; 2AKL A; 2F4O A; 2JNY A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
