The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
25
|
sequence length |
158
|
structure length |
155
|
Chain Sequence |
PFVSCQRGYRGVWRGDGIMHTRCHCGAEITGHVKNGTMRIVGPRTCRNMWSGTFPINAYTTGPCTPLPAPNYKFALWRVSAEEYVEIRRVGDFHYVSGMTTDNLKCPCQIPSPEFFTELDGVRLHRFAPPCKPLLREVSFRVHEYPVGSQLPCEP
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
The Crystal Structure of Ns5A Domain 1 from Genotype 1A Reveals New Clues to the Mechanism of Action for Dimeric Hcv Inhibitors.
pubmed doi rcsb |
| molecule keywords |
NON-STRUCTURAL PROTEIN 5A
|
| molecule tags |
Viral protein
|
| source organism |
Hepatitis c virus (isolate h77)
|
| total genus |
25
|
| structure length |
155
|
| sequence length |
158
|
| chains with identical sequence |
B, C, D
|
| ec nomenclature | |
| pdb deposition date | 2014-01-10 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF08300 | HCV_NS5a_1a | Hepatitis C virus non-structural 5a zinc finger domain |
| A | PF08301 | HCV_NS5a_1b | Hepatitis C virus non-structural 5a domain 1b |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Single Sheet | N-terminal domain of TfIIb | N-terminal domain of TfIIb | ||
| Mainly Beta | Single Sheet | N-terminal domain of TfIIb | N-terminal domain of TfIIb |
#chains in the Genus database with same CATH superfamily 1ZH1 A; 4CL1 A; 3FQQ A; 3FQM A; #chains in the Genus database with same CATH topology 2QRE B; 2QRC B; 2JA8 I; 2QLV B; 1VQM 1; 3S15 I; 2R93 I; 5IT9 b; 1QVF Z; 2E2I I; 4HGZ A; 3S2H I; 3MZK B; 2V8I A; 3J81 f; 2AKL A; 4CL1 A; 3TDH B; 3H0G I; 4X6A I; 4MON A; 2JIQ A; 1Q7Y 1; 4BXX I; 2P28 A; 3ESW A; 1K73 1; 3CC7 Z; 2RIQ A; 4E31 A; 3NH8 A; 3JAM b; 1WW9 A; 3CCQ Z; 3CCS 1; 2JIO A; 4QTU A; 1WZN A; 5D1O B; 1ZB9 A; 1P9N A; 1VQK Z; 2DE5 A; 2OTL Z; 1YHQ Z; 3I56 1; 1YI2 1; 1VQN Z; 2R92 I; 2JA5 I; 4NBG A; 3LUS A; 1YJ9 1; 2W04 A; 3IF8 A; 1KD1 2; 2RHB A; 1Q86 1; 5C4J I; 3M3Y I; 1NJI 2; 3GTG I; 2E9H A; 1VQ8 1; 3NFZ A; 3BG0 B; 2GTI A; 3HOX I; 1VQ9 Z; 1YJN Z; 2OTJ 1; 4RVD A; 2K3R A; 2RT9 A; 2YAD A; 4E2Z A; 3OW2 Y; 3FQM A; 3CC2 1; 1RO2 A; 2JIR A; 3VTN A; 3NH5 A; 4A3J I; 2Y0S A; 1JJ2 Y; 4DK1 A; 3GTJ I; 1KQS Z; 2VPX A; 4DQY B; 4E32 A; 2HU9 A; 3CXC Y; 3GTK I; 4A3G I; 1Y1V S; 1TWG I; 2YU9 I; 4AYB A; 3CCU 1; 1Q7Y 2; 2JUB A; 2RBL A; 4MD8 A; 1K73 2; 4NOZ A; 5C3E I; 2JNY A; 3PO3 I; 1W2B Y; 1QVG Y; 4RVF A; 3HOV I; 4MH4 A; 3G71 Z; 3D6W A; 2OOX B; 2O4H A; 2EGT A; 1VQ7 1; 3CPW Z; 3CD6 1; 3VMG A; 1YUA A; 2E7Z A; 3NDI A; 1YIT 1; 3FKI I; 5A2Q f; 1Q81 1; 5IP7 I; 2QRD B; 3S14 I; 2WB1 A; 1M1K 2; 1VQP 1; 4MXU A; 4RS4 A; 1L1O C; 1Z01 A; 3KIF A; 2JS4 A; 4A93 I; 3CCV Z; 3M4O I; 2QR1 B; 2VPZ A; 3CCM 1; 3I55 Z; 5FLX f; 1ML8 A; 3J80 f; 4E2X A; 1VQL 1; 3G6E Z; 2KI7 B; 1YIJ 1; 1S72 Z; 1VQO Z; 3CME 1; 3CC7 1; 2KPI A; 2NVQ I; 5T6B A; 2F4M A; 4RV9 A; 4BY1 I; 4EWC A; 3CCQ 1; 5IT9 f; 1VQK 1; 1RLY A; 3CMA Z; 3CCJ Z; 2IZ4 A; 1YJW Z; 1VQN 1; 4A3K I; 1QF8 A; 2PMZ A; 1USP B; 1AA6 A; 3CCR Z; 2LIY A; 1K83 I; 3GTM S; 2QA4 Z; 3S1M I; 2JMO A; 3HOU I; 5D1O A; 2R7Z I; 1Q81 2; 3NDJ A; 1VQ9 1; 3GTQ I; 3HOZ I; 2NVT I; 1X3W A; 4A3I I; 1VQM Z; 3CQZ I; 1Y1V I; 1Z03 A; 3T4N B; 1R9T I; 2OOY B; 3CC4 Z; 2HF1 A; 3MZL B; 3K7A I; 2VPY A; 2E2J I; 2V8J A; 3CCL Z; 2RPR A; 4RVG A; 4E30 A; 3Q87 A; 2BJO A; 3EER A; 3CCS Z; 4HGY A; 2JR6 A; 1VQ5 1; 3S2D I; 5C4X I; 1TWA I; 4DGL A; 3I56 Z; 2DE6 A; 3CCE Z; 1YI2 Z; 1Z02 A; 4QTT A; 1RO0 A; 4Y52 I; 1YJ9 Z; 3P5J B; 1S7M A; 1PFT A; 3GCF A; 3S1N I; 3D2L A; 1JJ2 Z; 3VMI A; 4E33 A; 4XX2 A; 1N8R 1; 2JA7 I; 1VQ4 Z; 2VPW A; 3CCV 1; 3CXC Z; 4BBR I; 3F3F C; 3HKZ A; 3I55 1; 2G2K A; 1W2B Z; 2M48 A; 3F3P C; 3CC2 Z; 1DL6 A; 1ZH1 A; 1VQ6 1; 1VLA A; 1SFO I; 1S72 1; 1VQO 1; 1Q86 2; 3I07 A; 1LQL A; 3RZD I; 1RO4 A; 1RQF A; 3VB9 A; 3NH4 A; 3CCU Z; 1Y1W I; 3U50 C; 1I50 I; 2IZ3 A; 3GTM I; 2DE7 A; 5C44 I; 5FLM I; 1I3Q I; 1YJW 1; 4A3D I; 2VUG A; 1KD1 1; 2PK7 A; 4A3L I; 2F4O A; 5T64 A; 2QEX Z; 4S1T A; 3CCR 1; 1Q82 1; 1VQ7 Z; 4MD9 A; 2M6N A; 1QVF Y; 2GU2 A; 2NVY I; 4NBA A; 2V3V A; 1YIT Z; 1X0T A; 5FLX b; 3J80 b; 1FDO A; 1QYP A; 2OTL 1; 4NBC A; 1YHQ 1; 1VQP Z; 2PM9 A; 3G4S Z; 4BY7 I; 4A3C I; 4A3E I; 1SIW A; 3S17 I; 4NH1 C; 4RVH A; 1N8R 2; 1USP A; 4A3B I; 3CCM Z; 3KIH A; 3JAM f; 3GTL I; 1RNI A; 4NBH A; 1ZB8 A; 3J81 b; 3J7A 4; 1X3Z A; 1TFI A; 3CC4 1; 3HOW I; 2W03 A; 3I4N I; 1VQL Z; 2J6A A; 2QKD A; 4A3M I; 4HH4 A; 1YIJ Z; 3CME Z; 1YJN 1; 3CCL 1; 3EED A; 3S16 I; 1JWH C; 2B63 I; 1K9M 1; 3D9X A; 2WAQ A; 1WJ2 A; 1K8A 1; 3CCE 1; 1NUI A; 3GTO I; 4NB8 A; 2GTH A; 5LL6 f; 2LEX A; 1TWF I; 2VUM I; 1M1K 1; 1WCM I; 2V45 A; 1Q82 2; 1WII A; 3G71 1; 2R6M A; 4NB9 A; 4E2Y A; 1KQS Y; 1VQ4 1; 2V8K A; 1KC8 1; 1M90 1; 4MD7 A; 2I3C A; 2Q51 A; 3IX0 A; 4NFR A; 4NBE A; 2LFU A; 3OW2 Z; 1KRL A; 5CM2 M; 3GKQ A; 1VQ8 Z; 1FDI A; 2IV2 X; 3MON A; 3CPW Y; 2OTJ Z; 4NBB A; 1TWH I; 1QVG Z; 3HOY I; 2Q4Z A; 1N2F A; 3PO2 I; 1VQ5 Z; 3FQQ A; 4A3F I; 2JIP A; 3G6E 1; 2ZAE B; 4Y7N I; 1K9M 2; 3S1Q I; 3IFU A; 2QEX 1; 1K8A 2; 1TWC I; 3TE5 B; 5A2Q b; 3BG1 B; 2OZK A; 1Y8C A; 5D1P A; 1Q16 A; 4MRI A; 3IR7 A; 2NAP A; 2JA6 I; 3CMA 1; 3CCJ 1; 3RZO I; 5AN9 F; 1QXF A; 3G4S 1; 1YUK A; 3PO3 S; 3GTP I; 4TNU A; 4NBF A; 4BBS I; 2NVX I; 2O53 A; 3I4M I; 2QA4 1; 4NBD A; 5T67 A; 3CD6 Z; 1NP6 A; 1KC8 2; 1M90 2; 3QWU A; 1NJI 1; 1I6H I; 4E2W A; 2P3Y A; 2AYD A; 5IP9 I; 2JIM A; 3H3V J; 2H85 A; 1VQ6 Z; 2K5R A; 2E2H I; 3VMH A; 3S1R I; 2VF1 A; #chains in the Genus database with same CATH homology 2QRE B; 2QRC B; 2JA8 I; 2QLV B; 1VQM 1; 3S15 I; 2R93 I; 5IT9 b; 1QVF Z; 2E2I I; 4HGZ A; 3S2H I; 3MZK B; 2V8I A; 3J81 f; 2AKL A; 4CL1 A; 3TDH B; 3H0G I; 4X6A I; 4MON A; 1Q7Y 1; 4BXX I; 2P28 A; 3ESW A; 1K73 1; 3CC7 Z; 2RIQ A; 4E31 A; 3NH8 A; 3JAM b; 1WW9 A; 3CCQ Z; 3CCS 1; 4QTU A; 5D1O B; 1ZB9 A; 1P9N A; 1VQK Z; 2DE5 A; 2OTL Z; 1YHQ Z; 3I56 1; 1YI2 1; 1VQN Z; 2R92 I; 2JA5 I; 4NBG A; 3LUS A; 1YJ9 1; 2W04 A; 3IF8 A; 1KD1 2; 2RHB A; 1Q86 1; 5C4J I; 3M3Y I; 1NJI 2; 3GTG I; 2E9H A; 1VQ8 1; 3NFZ A; 3BG0 B; 2GTI A; 3HOX I; 1VQ9 Z; 1YJN Z; 2OTJ 1; 4RVD A; 2K3R A; 2RT9 A; 2YAD A; 4E2Z A; 3OW2 Y; 3FQM A; 3CC2 1; 1RO2 A; 3VTN A; 3NH5 A; 4A3J I; 2Y0S A; 1JJ2 Y; 4DK1 A; 3GTJ I; 1KQS Z; 4DQY B; 4E32 A; 2HU9 A; 3CXC Y; 3GTK I; 4A3G I; 1Y1V S; 1TWG I; 2YU9 I; 4AYB A; 3CCU 1; 1Q7Y 2; 2JUB A; 2RBL A; 4MD8 A; 1K73 2; 4NOZ A; 5C3E I; 2JNY A; 3PO3 I; 1W2B Y; 1QVG Y; 4RVF A; 3HOV I; 4MH4 A; 3G71 Z; 3D6W A; 2OOX B; 2O4H A; 2EGT A; 1VQ7 1; 3CPW Z; 3CD6 1; 3VMG A; 1YUA A; 3NDI A; 1YIT 1; 3FKI I; 5A2Q f; 1Q81 1; 5IP7 I; 2QRD B; 3S14 I; 2WB1 A; 1M1K 2; 1VQP 1; 4MXU A; 4RS4 A; 1L1O C; 1Z01 A; 3KIF A; 2JS4 A; 4A93 I; 3CCV Z; 3M4O I; 2QR1 B; 3CCM 1; 3I55 Z; 5FLX f; 1ML8 A; 3J80 f; 4E2X A; 1VQL 1; 3G6E Z; 2KI7 B; 1YIJ 1; 1S72 Z; 1VQO Z; 3CME 1; 3CC7 1; 2KPI A; 2NVQ I; 5T6B A; 2F4M A; 4RV9 A; 4BY1 I; 4EWC A; 3CCQ 1; 5IT9 f; 1VQK 1; 1RLY A; 3CMA Z; 3CCJ Z; 2IZ4 A; 1YJW Z; 1VQN 1; 4A3K I; 1QF8 A; 2PMZ A; 1USP B; 3CCR Z; 2LIY A; 1K83 I; 3GTM S; 2QA4 Z; 3S1M I; 2JMO A; 3HOU I; 5D1O A; 2R7Z I; 1Q81 2; 3NDJ A; 1VQ9 1; 3GTQ I; 3HOZ I; 2NVT I; 1X3W A; 4A3I I; 1VQM Z; 3CQZ I; 1Y1V I; 1Z03 A; 3T4N B; 1R9T I; 2OOY B; 3CC4 Z; 2HF1 A; 3MZL B; 3K7A I; 2E2J I; 2V8J A; 3CCL Z; 2RPR A; 4RVG A; 4E30 A; 3Q87 A; 2BJO A; 3EER A; 3CCS Z; 4HGY A; 2JR6 A; 1VQ5 1; 3S2D I; 5C4X I; 1TWA I; 4DGL A; 3I56 Z; 2DE6 A; 3CCE Z; 1YI2 Z; 1Z02 A; 4QTT A; 1RO0 A; 4Y52 I; 1YJ9 Z; 3P5J B; 1S7M A; 1PFT A; 3GCF A; 3S1N I; 1JJ2 Z; 3VMI A; 4E33 A; 4XX2 A; 1N8R 1; 2JA7 I; 1VQ4 Z; 3CCV 1; 3CXC Z; 4BBR I; 3F3F C; 3HKZ A; 3I55 1; 2G2K A; 1W2B Z; 2M48 A; 3F3P C; 3CC2 Z; 1DL6 A; 1ZH1 A; 1VQ6 1; 1VLA A; 1SFO I; 1S72 1; 1VQO 1; 1Q86 2; 3I07 A; 1LQL A; 3RZD I; 1RO4 A; 1RQF A; 3VB9 A; 3NH4 A; 3CCU Z; 1Y1W I; 3U50 C; 1I50 I; 2IZ3 A; 3GTM I; 2DE7 A; 5C44 I; 5FLM I; 1I3Q I; 1YJW 1; 4A3D I; 2VUG A; 1KD1 1; 2PK7 A; 4A3L I; 2F4O A; 5T64 A; 2QEX Z; 4S1T A; 3CCR 1; 1Q82 1; 1VQ7 Z; 4MD9 A; 2M6N A; 1QVF Y; 2GU2 A; 2NVY I; 4NBA A; 1YIT Z; 1X0T A; 5FLX b; 3J80 b; 1QYP A; 2OTL 1; 4NBC A; 1YHQ 1; 1VQP Z; 2PM9 A; 3G4S Z; 4BY7 I; 4A3C I; 4A3E I; 3S17 I; 4NH1 C; 4RVH A; 1N8R 2; 1USP A; 4A3B I; 3CCM Z; 3KIH A; 3JAM f; 3GTL I; 1RNI A; 4NBH A; 1ZB8 A; 3J81 b; 3J7A 4; 1X3Z A; 1TFI A; 3CC4 1; 3HOW I; 2W03 A; 3I4N I; 1VQL Z; 2J6A A; 2QKD A; 4A3M I; 4HH4 A; 1YIJ Z; 3CME Z; 1YJN 1; 3CCL 1; 3EED A; 3S16 I; 1JWH C; 2B63 I; 1K9M 1; 3D9X A; 2WAQ A; 1K8A 1; 3CCE 1; 1NUI A; 3GTO I; 4NB8 A; 2GTH A; 5LL6 f; 1TWF I; 2VUM I; 1M1K 1; 1WCM I; 1Q82 2; 1WII A; 3G71 1; 2R6M A; 4NB9 A; 4E2Y A; 1KQS Y; 1VQ4 1; 2V8K A; 1KC8 1; 1M90 1; 4MD7 A; 2I3C A; 2Q51 A; 3IX0 A; 4NFR A; 4NBE A; 2LFU A; 3OW2 Z; 1KRL A; 5CM2 M; 3GKQ A; 1VQ8 Z; 3MON A; 3CPW Y; 2OTJ Z; 4NBB A; 1TWH I; 1QVG Z; 3HOY I; 2Q4Z A; 1N2F A; 3PO2 I; 1VQ5 Z; 3FQQ A; 4A3F I; 3G6E 1; 2ZAE B; 4Y7N I; 1K9M 2; 3S1Q I; 3IFU A; 2QEX 1; 1K8A 2; 1TWC I; 3TE5 B; 5A2Q b; 3BG1 B; 2OZK A; 5D1P A; 4MRI A; 2JA6 I; 3CMA 1; 3CCJ 1; 3RZO I; 5AN9 F; 3G4S 1; 1YUK A; 3PO3 S; 3GTP I; 4TNU A; 4NBF A; 4BBS I; 2NVX I; 2O53 A; 3I4M I; 2QA4 1; 4NBD A; 5T67 A; 3CD6 Z; 1NP6 A; 1KC8 2; 1M90 2; 3QWU A; 1NJI 1; 1I6H I; 4E2W A; 2P3Y A; 5IP9 I; 3H3V J; 2H85 A; 1VQ6 Z; 2K5R A; 2E2H I; 3VMH A; 3S1R I; 2VF1 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
